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Conserved domains on  [gi|654552000|ref|WP_028019655|]
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MULTISPECIES: methyl-accepting chemotaxis protein [Enterobacter]

Protein Classification

methyl-accepting chemotaxis protein( domain architecture ID 1000955)

methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior

CATH:  1.10.287.950
Gene Ontology:  GO:0006935
PubMed:  18165013|20738376
SCOP:  4003862

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MCP_signal super family cl46910
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 3-515 2.64e-126

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


The actual alignment was detected with superfamily member PRK15048:

Pssm-ID: 481250 [Multi-domain]  Cd Length: 553  Bit Score: 379.74  E-value: 2.64e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000   3 MLRNFTIRFVMLTILGIFCLMWAGVGLYSTWSLSRVSDGNDVDRQLVKQMTVLSQGNDQYFRFVTRLSRA-----MEV-- 75
Cdd:PRK15048   1 MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSNQLREQQGELTSTWDLMLQTRINLSRSavrmmMDSsn 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000  76 -KAAGGTPDLASAQQALDNMGKKLAEMKAISPGPMDEQISAQVIGTWQALLdQGITPQMQQAKLETLDGY-RQQANNVTP 153
Cdd:PRK15048  81 qQSNAKVELLDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYY-TALTELIDYLDYGNTGAYfAQPTQGMQN 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 154 PLSRAFGAAAENFNNAAAKALDSTRVVVdNLTSMTRTVIITATIIGLLILLFTDRYlvaMLVKPLDRIRQQFRQIAQGDL 233
Cdd:PRK15048 160 AMGEAFAQYALSSEKLYRDIVTDNADDY-RFAQWQLAVIALVVVLILLVAWYGIRR---MLLTPLAKIIAHIREIAGGNL 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 234 SQPIEPFGRNCVGQLVPLLSAMQDSLREAVSTIRSGSENIWRGATEISSGNNDLSSRTEEQAAALEETAASMEQLTATVK 313
Cdd:PRK15048 236 ANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVK 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 314 LNAESARQASQLADVASTTASRGGSLVEEVVTTMSGISESSKKIAEITNVINSIAFQTNILALNAAVEAARAGEQGRGFA 393
Cdd:PRK15048 316 QNADNARQASQLAQSASDTAQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFA 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 394 VVAGEVRNLASRSANAAKEIEGLIADSVNRVEQGAQLVGDTGTTMDAILRDVTEVTTIMKQIASASEEQSKGISQVGIAI 473
Cdd:PRK15048 396 VVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRVTDIMGEIASASDEQSRGIDQVALAV 475

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|..
gi 654552000 474 TQMDGVTQQNASLVEEVSAAAAALERQTEDLQRSVQKFRLTA 515
Cdd:PRK15048 476 SEMDRVTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLAA 517
 
Name Accession Description Interval E-value
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 3-515 2.64e-126

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 379.74  E-value: 2.64e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000   3 MLRNFTIRFVMLTILGIFCLMWAGVGLYSTWSLSRVSDGNDVDRQLVKQMTVLSQGNDQYFRFVTRLSRA-----MEV-- 75
Cdd:PRK15048   1 MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSNQLREQQGELTSTWDLMLQTRINLSRSavrmmMDSsn 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000  76 -KAAGGTPDLASAQQALDNMGKKLAEMKAISPGPMDEQISAQVIGTWQALLdQGITPQMQQAKLETLDGY-RQQANNVTP 153
Cdd:PRK15048  81 qQSNAKVELLDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYY-TALTELIDYLDYGNTGAYfAQPTQGMQN 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 154 PLSRAFGAAAENFNNAAAKALDSTRVVVdNLTSMTRTVIITATIIGLLILLFTDRYlvaMLVKPLDRIRQQFRQIAQGDL 233
Cdd:PRK15048 160 AMGEAFAQYALSSEKLYRDIVTDNADDY-RFAQWQLAVIALVVVLILLVAWYGIRR---MLLTPLAKIIAHIREIAGGNL 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 234 SQPIEPFGRNCVGQLVPLLSAMQDSLREAVSTIRSGSENIWRGATEISSGNNDLSSRTEEQAAALEETAASMEQLTATVK 313
Cdd:PRK15048 236 ANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVK 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 314 LNAESARQASQLADVASTTASRGGSLVEEVVTTMSGISESSKKIAEITNVINSIAFQTNILALNAAVEAARAGEQGRGFA 393
Cdd:PRK15048 316 QNADNARQASQLAQSASDTAQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFA 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 394 VVAGEVRNLASRSANAAKEIEGLIADSVNRVEQGAQLVGDTGTTMDAILRDVTEVTTIMKQIASASEEQSKGISQVGIAI 473
Cdd:PRK15048 396 VVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRVTDIMGEIASASDEQSRGIDQVALAV 475

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|..
gi 654552000 474 TQMDGVTQQNASLVEEVSAAAAALERQTEDLQRSVQKFRLTA 515
Cdd:PRK15048 476 SEMDRVTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLAA 517
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
3-513 3.48e-93

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 293.85  E-value: 3.48e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000   3 MLRNFTIRFVMLTILGIFCLMWAGVGLYSTWSLSRVSDGNDVDRQLVKQMTVLSQGNDQYFRFVTRLSRAMEVKAAGGTP 82
Cdd:COG0840    1 LLILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000  83 DLASAQQALDNMGKKLAEMKAISPGPMDEQISAQVIGTWQALLDQGITPQMQQAKLETLDGYRQQAnnvtppLSRAFGAA 162
Cdd:COG0840   81 LLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALA------LLALALLA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 163 AENFNNAAAKALDSTRVVVDNLTSMTRTVIITATIIGLLILLFTDRYLVAMLVKPLDRIRQQFRQIAQGDLSQPIEPFGR 242
Cdd:COG0840  155 AAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSK 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 243 NCVGQLVPLLSAMQDSLREAVSTIRSGSENIWRGATEISSGNNDLSSRTEEQAAALEETAASMEQLTATVKLNAESARQA 322
Cdd:COG0840  235 DEIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQA 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 323 SQLADVASTTASRGGSLVEEVVT--------------TMSGISESSKKIAEITNVINSIAFQTNILALNAAVEAARAGEQ 388
Cdd:COG0840  315 AELAEEASELAEEGGEVVEEAVEgieeiresveetaeTIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEA 394

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 389 GRGFAVVAGEVRNLASRSANAAKEIEGLIADSVNRVEQGAQL--------------VGDTGTTMDAILRDVTEVTTIMKQ 454
Cdd:COG0840  395 GRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAmeegseeveegvelVEEAGEALEEIVEAVEEVSDLIQE 474

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 654552000 455 IASASEEQSKGISQVGIAITQMDGVTQQNASLVEEVSAAAAALERQTEDLQRSVQKFRL 513
Cdd:COG0840  475 IAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 265-512 4.23e-74

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 235.26  E-value: 4.23e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000   265 TIRSGSENIWRGATEISSGNNDLSSRTEEQAAALEETAASMEQLTATVKLNAESARQASQLADVASTTASRGGSLVEEVV 344
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000   345 TTMSGISESSKKIAEITNVINSIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSANAAKEIEGLIAD----- 419
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEiqeet 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000   420 ---------SVNRVEQGAQLVGDTGTTMDAILRDVTEVTTIMKQIASASEEQSKGISQVGIAITQMDGVTQQNASLVEEV 490
Cdd:smart00283 161 neavaameeSSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250       260
                   ....*....|....*....|..
gi 654552000   491 SAAAAALERQTEDLQRSVQKFR 512
Cdd:smart00283 241 SAAAEELSGLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 292-491 1.15e-61

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 200.54  E-value: 1.15e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 292 EEQAAALEETAASMEQLTATVKLNAESARQASQLADVASTTASRGGSLVEEVVTTMSGISESSKKIAEITNVINSIAFQT 371
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 372 NILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSANAAKEIEGLIADSVNRVEQGAQLVGDTGTTMDAILRDVTEVTTI 451
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 654552000 452 MKQIASASEEQSKGISQVGIAITQMDGVTQQNASLVEEVS 491
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 323-480 6.37e-55

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 182.25  E-value: 6.37e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000  323 SQLADVASTTASRGGSLVEEVVTTMSGISESSKKIAEITNVINSIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNL 402
Cdd:pfam00015   1 SDLAQLASEEAQDGGKEVANVVGQMEQIAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000  403 ASRSANAAKEIEGLIA--------------DSVNRVEQGAQLVGDTGTTMDAILRDVTEVTTIMKQIASASEEQSKGISQ 468
Cdd:pfam00015  81 AERSAQAAKEIEALIIeiqkqtndstasieSTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQ 160

                         170
                  ....*....|..
gi 654552000  469 VGIAITQMDGVT 480
Cdd:pfam00015 161 VNQAVARMDQVT 172
 
Name Accession Description Interval E-value
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 3-515 2.64e-126

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 379.74  E-value: 2.64e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000   3 MLRNFTIRFVMLTILGIFCLMWAGVGLYSTWSLSRVSDGNDVDRQLVKQMTVLSQGNDQYFRFVTRLSRA-----MEV-- 75
Cdd:PRK15048   1 MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSNQLREQQGELTSTWDLMLQTRINLSRSavrmmMDSsn 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000  76 -KAAGGTPDLASAQQALDNMGKKLAEMKAISPGPMDEQISAQVIGTWQALLdQGITPQMQQAKLETLDGY-RQQANNVTP 153
Cdd:PRK15048  81 qQSNAKVELLDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYY-TALTELIDYLDYGNTGAYfAQPTQGMQN 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 154 PLSRAFGAAAENFNNAAAKALDSTRVVVdNLTSMTRTVIITATIIGLLILLFTDRYlvaMLVKPLDRIRQQFRQIAQGDL 233
Cdd:PRK15048 160 AMGEAFAQYALSSEKLYRDIVTDNADDY-RFAQWQLAVIALVVVLILLVAWYGIRR---MLLTPLAKIIAHIREIAGGNL 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 234 SQPIEPFGRNCVGQLVPLLSAMQDSLREAVSTIRSGSENIWRGATEISSGNNDLSSRTEEQAAALEETAASMEQLTATVK 313
Cdd:PRK15048 236 ANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVK 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 314 LNAESARQASQLADVASTTASRGGSLVEEVVTTMSGISESSKKIAEITNVINSIAFQTNILALNAAVEAARAGEQGRGFA 393
Cdd:PRK15048 316 QNADNARQASQLAQSASDTAQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFA 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 394 VVAGEVRNLASRSANAAKEIEGLIADSVNRVEQGAQLVGDTGTTMDAILRDVTEVTTIMKQIASASEEQSKGISQVGIAI 473
Cdd:PRK15048 396 VVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRVTDIMGEIASASDEQSRGIDQVALAV 475

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|..
gi 654552000 474 TQMDGVTQQNASLVEEVSAAAAALERQTEDLQRSVQKFRLTA 515
Cdd:PRK15048 476 SEMDRVTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLAA 517
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
180-513 2.49e-120

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 364.66  E-value: 2.49e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 180 VVDNLTSMTRTVIITATIIGLLILLFTDRYL--VAMLVKPLDRIRQQFRQIAQGDLSQPIEPFGRNCVGQLVPLLSAMQD 257
Cdd:PRK15041 182 VSDNNASYSQAMWILVGVMIVVLAVIFAVWFgiKASLVAPMNRLIDSIRHIAGGDLVKPIEVDGSNEMGQLAESLRHMQG 261

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 258 SLREAVSTIRSGSENIWRGATEISSGNNDLSSRTEEQAAALEETAASMEQLTATVKLNAESARQASQLADVASTTASRGG 337
Cdd:PRK15041 262 ELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGG 341

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 338 SLVEEVVTTMSGISESSKKIAEITNVINSIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSANAAKEIEGLI 417
Cdd:PRK15041 342 KVVDNVVQTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSLI 421

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 418 ADSVNRVEQGAQLVGDTGTTMDAILRDVTEVTTIMKQIASASEEQSKGISQVGIAITQMDGVTQQNASLVEEVSAAAAAL 497
Cdd:PRK15041 422 EDSVGKVDVGSTLVESAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAAL 501

                        330
                 ....*....|....*.
gi 654552000 498 ERQTEDLQRSVQKFRL 513
Cdd:PRK15041 502 EEQASRLTEAVAVFRI 517
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
190-513 1.39e-113

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 346.29  E-value: 1.39e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 190 TVIITATIIGLLILLFTDRylvaMLVKPLDRIRQQFRQIAQGDLSQPIEPFGRNCVGQLVPLLSAMQDSLREAVSTIRSG 269
Cdd:PRK09793 194 SMIIVAAIYISSALWWTRK----MIVQPLAIIGSHFDSIAAGNLARPIAVYGRNEITAIFASLKTMQQALRGTVSDVRKG 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 270 SENIWRGATEISSGNNDLSSRTEEQAAALEETAASMEQLTATVKLNAESARQASQLADVASTTASRGGSLVEEVVTTMSG 349
Cdd:PRK09793 270 SQEMHIGIAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNARQASELAKNAATTAQAGGVQVSTMTHTMQE 349

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 350 ISESSKKIAEITNVINSIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSANAAKEIEGLIADSVNRVEQGAQ 429
Cdd:PRK09793 350 IATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKGLIEESVNRVQQGSK 429

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 430 LVGDTGTTMDAILRDVTEVTTIMKQIASASEEQSKGISQVGIAITQMDGVTQQNASLVEEVSAAAAALERQTEDLQRSVQ 509
Cdd:PRK09793 430 LVNNAAATMTDIVSSVTRVNDIMGEIASASEEQRRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRVA 509


                 ....
gi 654552000 510 KFRL 513
Cdd:PRK09793 510 VFTL 513
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
3-513 3.48e-93

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 293.85  E-value: 3.48e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000   3 MLRNFTIRFVMLTILGIFCLMWAGVGLYSTWSLSRVSDGNDVDRQLVKQMTVLSQGNDQYFRFVTRLSRAMEVKAAGGTP 82
Cdd:COG0840    1 LLILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000  83 DLASAQQALDNMGKKLAEMKAISPGPMDEQISAQVIGTWQALLDQGITPQMQQAKLETLDGYRQQAnnvtppLSRAFGAA 162
Cdd:COG0840   81 LLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALA------LLALALLA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 163 AENFNNAAAKALDSTRVVVDNLTSMTRTVIITATIIGLLILLFTDRYLVAMLVKPLDRIRQQFRQIAQGDLSQPIEPFGR 242
Cdd:COG0840  155 AAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSK 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 243 NCVGQLVPLLSAMQDSLREAVSTIRSGSENIWRGATEISSGNNDLSSRTEEQAAALEETAASMEQLTATVKLNAESARQA 322
Cdd:COG0840  235 DEIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQA 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 323 SQLADVASTTASRGGSLVEEVVT--------------TMSGISESSKKIAEITNVINSIAFQTNILALNAAVEAARAGEQ 388
Cdd:COG0840  315 AELAEEASELAEEGGEVVEEAVEgieeiresveetaeTIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEA 394

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 389 GRGFAVVAGEVRNLASRSANAAKEIEGLIADSVNRVEQGAQL--------------VGDTGTTMDAILRDVTEVTTIMKQ 454
Cdd:COG0840  395 GRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAmeegseeveegvelVEEAGEALEEIVEAVEEVSDLIQE 474

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 654552000 455 IASASEEQSKGISQVGIAITQMDGVTQQNASLVEEVSAAAAALERQTEDLQRSVQKFRL 513
Cdd:COG0840  475 IAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 265-512 4.23e-74

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 235.26  E-value: 4.23e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000   265 TIRSGSENIWRGATEISSGNNDLSSRTEEQAAALEETAASMEQLTATVKLNAESARQASQLADVASTTASRGGSLVEEVV 344
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000   345 TTMSGISESSKKIAEITNVINSIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSANAAKEIEGLIAD----- 419
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEiqeet 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000   420 ---------SVNRVEQGAQLVGDTGTTMDAILRDVTEVTTIMKQIASASEEQSKGISQVGIAITQMDGVTQQNASLVEEV 490
Cdd:smart00283 161 neavaameeSSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250       260
                   ....*....|....*....|..
gi 654552000   491 SAAAAALERQTEDLQRSVQKFR 512
Cdd:smart00283 241 SAAAEELSGLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 292-491 1.15e-61

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 200.54  E-value: 1.15e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 292 EEQAAALEETAASMEQLTATVKLNAESARQASQLADVASTTASRGGSLVEEVVTTMSGISESSKKIAEITNVINSIAFQT 371
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 372 NILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSANAAKEIEGLIADSVNRVEQGAQLVGDTGTTMDAILRDVTEVTTI 451
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 654552000 452 MKQIASASEEQSKGISQVGIAITQMDGVTQQNASLVEEVS 491
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 323-480 6.37e-55

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 182.25  E-value: 6.37e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000  323 SQLADVASTTASRGGSLVEEVVTTMSGISESSKKIAEITNVINSIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNL 402
Cdd:pfam00015   1 SDLAQLASEEAQDGGKEVANVVGQMEQIAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000  403 ASRSANAAKEIEGLIA--------------DSVNRVEQGAQLVGDTGTTMDAILRDVTEVTTIMKQIASASEEQSKGISQ 468
Cdd:pfam00015  81 AERSAQAAKEIEALIIeiqkqtndstasieSTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQ 160

                         170
                  ....*....|..
gi 654552000  469 VGIAITQMDGVT 480
Cdd:pfam00015 161 VNQAVARMDQVT 172
HAMP smart00304
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
214-264 6.33e-06

HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;


Pssm-ID: 197640 [Multi-domain]  Cd Length: 53  Bit Score: 43.39  E-value: 6.33e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 654552000   214 LVKPLDRIRQQFRQIAQGDLSQPIEPFGRNCVGQLVPLLSAMQDSLREAVS 264
Cdd:smart00304   3 LLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
HAMP pfam00672
HAMP domain;
210-261 7.17e-06

HAMP domain;


Pssm-ID: 459898 [Multi-domain]  Cd Length: 53  Bit Score: 43.38  E-value: 7.17e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 654552000  210 LVAMLVKPLDRIRQQFRQIAQGDLSQPIEPFGRNCVGQLVPLLSAMQDSLRE 261
Cdd:pfam00672   2 LARRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
NtrY COG5000
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ...
 185-262 2.36e-05

Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];


Pssm-ID: 444024 [Multi-domain]  Cd Length: 422  Bit Score: 46.88  E-value: 2.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 185 TSMTRTVIITATIIGLLILLFTD---RYLVAMLVKPLDRIRQQFRQIAQGDLSQPIEPFGRNCVGQLVPLLSAMQDSLRE 261
Cdd:COG5000    1 SGLQILFLLLLLLIALLLLLLALwlaLLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAFNRMTDQLKE 80


                 .
gi 654552000 262 A 262
Cdd:COG5000   81 Q 81
HAMP cd06225
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ...
 215-259 3.82e-05

Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.


Pssm-ID: 381743 [Multi-domain]  Cd Length: 45  Bit Score: 40.89  E-value: 3.82e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 654552000 215 VKPLDRIRQQFRQIAQGDLSQPIEPFGRNCVGQLVPLLSAMQDSL 259
Cdd:cd06225    1 TRPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
NarQ COG3850
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ...
 187-502 4.06e-04

Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];


Pssm-ID: 443059 [Multi-domain]  Cd Length: 448  Bit Score: 42.95  E-value: 4.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 187 MTRTVIITATIIGLLILLFTDRYLVAMLVKPLDRIRQQFRQIAQGDLSQPIEPFGRNCVGQLVPLLSAMQDSLREAVSTI 266
Cdd:COG3850  115 INRKLALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARAFNRMADELQELYAEL 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 267 RSGSENIWRGATEISSGNNDLSSRTEEQAAALEETAASMEQLTATVKLNAESARQASQLADVASTTASRGGSLVEEVVTT 346
Cdd:COG3850  195 EEEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLLALLLLLL 274

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 347 MSGISESSKKIAEITNVINSIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSANAAKEIEGLIADSVNRVEQ 426
Cdd:COG3850  275 ASALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELASILALQAALE 354

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 654552000 427 GAQLVGDTGTTMDAILRDVTEVTTIMKQIASASEEQSKGISQVGIAITQMDGVTQQNASLVEEVSAAAAALERQTE 502
Cdd:COG3850  355 AAAAGAALAAAAAAAGLARALAQAGADAAEALGLLAEASEGAAGQGAGLVDVEGGVAGEGGLVVLIVSIIAGGEAI 430
HAMP COG2770
HAMP domain [Signal transduction mechanisms];
9-509 6.55e-04

HAMP domain [Signal transduction mechanisms];


Pssm-ID: 442051 [Multi-domain]  Cd Length: 631  Bit Score: 42.41  E-value: 6.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000   9 IRFVMLTILGIFCLMWAGVGLYSTWSLSRVSDGNDVDRQLVKQMTVLSQGNDQYFRFVTRLSRAMEVKAAGGTPDLASAQ 88
Cdd:COG2770   31 ISLRLLLALLLLLLLLLALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALLLLLAALL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000  89 QALDNMGKKLAEMKAISPGPMDEQISAQVIGTWQALLDQGITPQMQQAKLETLDGYRQQANNVTPPLSRAFGAAAENFNN 168
Cdd:COG2770  111 LLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAALLAAL 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 169 AAAKALDSTRVVVDNLTSMTRTVIITATIIGLLILLFTDRYLVAMLVKPLDRIRQQFRQIAQGDLSQPIEPFGRNCVGQL 248
Cdd:COG2770  191 LLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSRKDEIGEL 270

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 249 VPLLSAMQDSLREAVSTIRSGSENIWRGATEISSGNNDLSSRTEEQAAALEETAASMEQLTATVKLNAESARQASQLADV 328
Cdd:COG2770  271 ARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADL 350

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 329 ASTTASRGGSLVEEVVTTMSGISESSKKIAEITNVINSIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAN 408
Cdd:COG2770  351 LLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAA 430

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 409 AAKEIEGLIADSVNRVEQGAQLVGDTGTTMDAILRDVTEVTTIMKQIASASEEQSKGISQVGIAITQMDGVTQQNASLVE 488
Cdd:COG2770  431 AEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAAEELAEELL 510

                        490       500
                 ....*....|....*....|.
gi 654552000 489 EVSAAAAALERQTEDLQRSVQ 509
Cdd:COG2770  511 LLEGLLLLLLLEAEALEVAEE 531
YesM COG2972
Sensor histidine kinase YesM [Signal transduction mechanisms];
185-261 3.42e-03

Sensor histidine kinase YesM [Signal transduction mechanisms];


Pssm-ID: 442211 [Multi-domain]  Cd Length: 445  Bit Score: 40.00  E-value: 3.42e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 654552000 185 TSMTRTVIITATIIGLLILLFTDRYLVAMLVKPLDRIRQQFRQIAQGDLSQpIEPFGRNCVGQLVPLLSAMQDSLRE 261
Cdd:COG2972  152 LFSLRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLVR-LEVSGNDEIGILARSFNEMVERIKE 227
COG4192 COG4192
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ...
 116-262 6.87e-03

Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];


Pssm-ID: 443346 [Multi-domain]  Cd Length: 640  Bit Score: 39.28  E-value: 6.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654552000 116 QVIGTWQALL--DQGItPQMQQAKLE---TLDGYRQQANNvtppLSRAFGAAAENFNNAAAKALDSTRVVVDNLTSMTRT 190
Cdd:COG4192  252 QLIDELLAIGsgEGGL-PSLRRDELAaqaTLEALAEENNS----ILEQLRTQISGLVGNSREQLVALNQETAQLVQQSGI 326

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 654552000 191 VIITATIIGLLILLFTDRYLV-AMLVKPLDRIRQQFRQIAQGDLSQPIEPFGRNCVGQLVPLLSAMQDSLREA 262
Cdd:COG4192  327 LLLAIALLSLLLAVLINYFYVrRRLVKRLNALSDAMAAIAAGDLDVPIPVDGNDEIGRIARLLRVFRDQAIEK 399
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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