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Conserved domains on  [gi|654964286|ref|WP_028414037|]
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MULTISPECIES: type III polyketide synthase [Priestia]

Protein Classification

type III polyketide synthase( domain architecture ID 11465765)

type III polyketide synthase (PKS) is a homodimeric iterative PKS that contains two independent active sites each of which catalyzes single or multiple condensation reactions to generate polyketides of different lengths, similar to chalcone and stilbene synthase, which are involved in the synthesis of chalcone or stilbene, respectively, by catalyzing the addition of three molecules of malonyl-CoA to a starter CoA ester

CATH:  3.40.47.10
EC:  2.3.1.-
Gene Ontology:  GO:0016747|GO:0030639
PubMed:  12636085|12714063|27862822|11828424|10476972
SCOP:  4000864

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BH0617 COG3424
Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and ...
 1-361 2.62e-175

Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 442650 [Multi-domain]  Cd Length: 351  Bit Score: 490.81  E-value: 2.62e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286   1 MPKIISVGFGVPPYELTQQDTLLFAKELFSESFKDINRLLTVFQNGQIEKRNFAKDLSWFQEDHTFEEKNDAFIECAVEL 80
Cdd:COG3424    1 SARILSIATAVPPHRYTQEEIAEFAAELFGLDERDRRRLRRLFENSGIETRHSVLPLEWYLEPPSFGERNALYIEEALEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  81 GTKAIEECLTNkdyvsTPLPCGEIDAIFYVSTSGVATPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLSRAYEYCKA 160
Cdd:COG3424   81 AEEAARRALDK-----AGLDPEDIDHLVTVSCTGFAAPGLDARLINRLGLRPDVRRLPVGGMGCAAGAAGLRRAADFLRA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 161 FPRAKVLVLSVELCSLTFQRNDRSKSNLIGTSLFADGVAAALVAGDEaditfsRSKSFPYILHTQSTLMPNSEDVMGWEI 240
Cdd:COG3424  156 DPDAVVLVVCVELCSLTFQRDDDSKDNLVANALFGDGAAAVVVSGDP------RPGPGPRILAFRSYLIPDTEDVMGWDV 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 241 KNDGLFVVFSKDIPTIIDSWLGGEVESFLQTQNLTSRDLKHFVAHPGGKKVLEAYVSTLSLNENMIADSLDVLKNHGNMS 320
Cdd:COG3424  230 GDTGFRMVLSPEVPDLIAEHLAPAVEPLLARHGLTIEDIDHWAVHPGGPKVLDAVEEALGLPPEALAHSREVLREYGNMS 309

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 654964286 321 SATVLYVLDRFMKKEIPSK-EYGLLTALGPGFSSEMLLLEWR 361
Cdd:COG3424  310 SATVLFVLERLLEEGAPAPgERGLAMAFGPGFTAELVLLRWE 351
 
Name Accession Description Interval E-value
BH0617 COG3424
Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and ...
 1-361 2.62e-175

Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442650 [Multi-domain]  Cd Length: 351  Bit Score: 490.81  E-value: 2.62e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286   1 MPKIISVGFGVPPYELTQQDTLLFAKELFSESFKDINRLLTVFQNGQIEKRNFAKDLSWFQEDHTFEEKNDAFIECAVEL 80
Cdd:COG3424    1 SARILSIATAVPPHRYTQEEIAEFAAELFGLDERDRRRLRRLFENSGIETRHSVLPLEWYLEPPSFGERNALYIEEALEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  81 GTKAIEECLTNkdyvsTPLPCGEIDAIFYVSTSGVATPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLSRAYEYCKA 160
Cdd:COG3424   81 AEEAARRALDK-----AGLDPEDIDHLVTVSCTGFAAPGLDARLINRLGLRPDVRRLPVGGMGCAAGAAGLRRAADFLRA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 161 FPRAKVLVLSVELCSLTFQRNDRSKSNLIGTSLFADGVAAALVAGDEaditfsRSKSFPYILHTQSTLMPNSEDVMGWEI 240
Cdd:COG3424  156 DPDAVVLVVCVELCSLTFQRDDDSKDNLVANALFGDGAAAVVVSGDP------RPGPGPRILAFRSYLIPDTEDVMGWDV 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 241 KNDGLFVVFSKDIPTIIDSWLGGEVESFLQTQNLTSRDLKHFVAHPGGKKVLEAYVSTLSLNENMIADSLDVLKNHGNMS 320
Cdd:COG3424  230 GDTGFRMVLSPEVPDLIAEHLAPAVEPLLARHGLTIEDIDHWAVHPGGPKVLDAVEEALGLPPEALAHSREVLREYGNMS 309

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 654964286 321 SATVLYVLDRFMKKEIPSK-EYGLLTALGPGFSSEMLLLEWR 361
Cdd:COG3424  310 SATVLFVLERLLEEGAPAPgERGLAMAFGPGFTAELVLLRWE 351
CHS_like cd00831
Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, ...
 1-358 4.06e-117

Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy, after the starter molecule is loaded onto the active site cysteine, a carboxylative condensation reation extends the polyketide chain. Plant-specific PKS are dimeric iterative PKSs, using coenzyme A esters to deliver substrate to the active site, but they differ in the choice of starter molecule and the number of condensation reactions.


Pssm-ID: 238427 [Multi-domain]  Cd Length: 361  Bit Score: 343.44  E-value: 4.06e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286   1 MPKIISVGFGVPPYELTQQDTLLFAKELFSES--FKDINRLLTVFQNGQIEKRNFAKD--LSWFQE----DHTFEEKNDA 72
Cdd:cd00831    1 AATILAIGTAVPPHRVPQSELVDFYRRLFSSDhlPELKEKLKRLCAKTGIETRYLVLPggEETYAPrpemSPSLDERNDI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  73 FIECAVELGTKAIEECLTNkdyvsTPLPCGEIDAIFYVSTSGVATPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLS 152
Cdd:cd00831   81 ALEEARELAEEAARGALDE-----AGLRPSDIDHLVVNTSTGNPTPSLDAMLINRLGLRPDVKRYNLGGMGCSAGAIALD 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 153 RAYEYCKAFPRAKVLVLSVELCSLTFQRNDrSKSNLIGTSLFADGVAAALVAGDEADitFSRSKSFPYILHTQSTLMPNS 232
Cdd:cd00831  156 LAKDLLEANPGARVLVVSTELCSLWYRGPD-HRSMLVGNALFGDGAAAVLLSNDPRD--RRRERPLFELVRAASTLLPDS 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 233 EDVMGWEIKNDGLFVVFSKDIPTIIDSWLGGEVESFLQTQ--NLTSRDLKHFVAHPGGKKVLEAYVSTLSLNENMIADSL 310
Cdd:cd00831  233 EDAMGWHLGEEGLTFVLSRDVPRLVEKNLERVLRKLLARLgiGLFKLAFDHWCVHPGGRAVLDAVEKALGLSPEDLEASR 312

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 654964286 311 DVLKNHGNMSSATVLYVLDRFMKKEIPSK-EYGLLTALGPGFSSEMLLL 358
Cdd:cd00831  313 MVLRRYGNMSSSSVLYVLAYMEAKGRVKRgDRGLLIAFGPGFTCESAVW 361
PLN03169 PLN03169
chalcone synthase family protein; Provisional
 70-358 5.65e-31

chalcone synthase family protein; Provisional


Pssm-ID: 215612 [Multi-domain]  Cd Length: 391  Bit Score: 120.96  E-value: 5.65e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  70 NDAFIECAVELGTKAIEECltnkdyvstPLPCGEIDAIFYVSTSGVATPSIEARIMNKLAFSDHTKRIPIWGLGCAGGAS 149
Cdd:PLN03169 103 NEAVTQMAVEASLACIKEW---------GRPVSDITHLVYVSSSEARLPGGDLYLAKQLGLSPDVQRVMLYFLGCSGGVA 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 150 GLSRAYEYCKAFPRAKVLVLSVELCSLTFQ--RNDRSkSNLIGTSLFADGVAAALVAGDEADITFSrsksfPYI-LHT-- 224
Cdd:PLN03169 174 GLRVAKDIAENNPGSRVLLTTSETTILGFRppSPDRP-YDLVGAALFGDGAAAVIIGADPIPVSES-----PFFeLHTai 247

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 225 QSTLmPNSEDVMGWEIKNDGLFVVFSKDIPTIIDSwlggEVESFLQT----QNLTSRDL-KHFVA-HPGGKKVLEAYVST 298
Cdd:PLN03169 248 QQFL-PGTEKTIDGRLTEEGINFKLGRELPQKIED----NIEGFCKKlmkkAGLVEKDYnDLFWAvHPGGPAILNRLEKK 322

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 654964286 299 LSLNENMIADSLDVLKNHGNMSSATVLYVLDrFMKKEI-----PSKEYGLLTALGPGFSSEMLLL 358
Cdd:PLN03169 323 LKLAPEKLECSRRALMDYGNVSSNTIVYVLE-YMREELkkkgeEDEEWGLILAFGPGITFEGILA 386
Chal_sti_synt_C pfam02797
Chalcone and stilbene synthases, C-terminal domain; This domain of chalcone synthase is ...
 227-358 1.63e-17

Chalcone and stilbene synthases, C-terminal domain; This domain of chalcone synthase is reported to be structurally similar to domains in thiolase and beta-ketoacyl synthase. The differences in activity are accounted for by differences in the N-terminal domain.


Pssm-ID: 397089  Cd Length: 151  Bit Score: 78.65  E-value: 1.63e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  227 TLMPNSEDVMGWEIKNDGLFVVFSKDIPTIIDSwlggEVESFLQT--QNLTSRDLKH--FVAHPGGKKVLEAYVSTLSLN 302
Cdd:pfam02797   8 TFLPNTDGVIDGHLTEEGLTFHLGRDVPQKIEE----NIEEFLKKafEPLGISEWNSlfWIVHPGGPAILDRVETKLGLE 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 654964286  303 ENMIADSLDVLKNHGNMSSATVLYVLDRFMKKEI--------PSKEYGLLTALGPGFSSEMLLL 358
Cdd:pfam02797  84 PEKLEASRRALMDYGNVSSATVLFILDEMRKKSLkkglattgEGLDWGVLLAFGPGLTFETVVL 147
 
Name Accession Description Interval E-value
BH0617 COG3424
Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and ...
 1-361 2.62e-175

Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442650 [Multi-domain]  Cd Length: 351  Bit Score: 490.81  E-value: 2.62e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286   1 MPKIISVGFGVPPYELTQQDTLLFAKELFSESFKDINRLLTVFQNGQIEKRNFAKDLSWFQEDHTFEEKNDAFIECAVEL 80
Cdd:COG3424    1 SARILSIATAVPPHRYTQEEIAEFAAELFGLDERDRRRLRRLFENSGIETRHSVLPLEWYLEPPSFGERNALYIEEALEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  81 GTKAIEECLTNkdyvsTPLPCGEIDAIFYVSTSGVATPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLSRAYEYCKA 160
Cdd:COG3424   81 AEEAARRALDK-----AGLDPEDIDHLVTVSCTGFAAPGLDARLINRLGLRPDVRRLPVGGMGCAAGAAGLRRAADFLRA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 161 FPRAKVLVLSVELCSLTFQRNDRSKSNLIGTSLFADGVAAALVAGDEaditfsRSKSFPYILHTQSTLMPNSEDVMGWEI 240
Cdd:COG3424  156 DPDAVVLVVCVELCSLTFQRDDDSKDNLVANALFGDGAAAVVVSGDP------RPGPGPRILAFRSYLIPDTEDVMGWDV 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 241 KNDGLFVVFSKDIPTIIDSWLGGEVESFLQTQNLTSRDLKHFVAHPGGKKVLEAYVSTLSLNENMIADSLDVLKNHGNMS 320
Cdd:COG3424  230 GDTGFRMVLSPEVPDLIAEHLAPAVEPLLARHGLTIEDIDHWAVHPGGPKVLDAVEEALGLPPEALAHSREVLREYGNMS 309

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 654964286 321 SATVLYVLDRFMKKEIPSK-EYGLLTALGPGFSSEMLLLEWR 361
Cdd:COG3424  310 SATVLFVLERLLEEGAPAPgERGLAMAFGPGFTAELVLLRWE 351
CHS_like cd00831
Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, ...
 1-358 4.06e-117

Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy, after the starter molecule is loaded onto the active site cysteine, a carboxylative condensation reation extends the polyketide chain. Plant-specific PKS are dimeric iterative PKSs, using coenzyme A esters to deliver substrate to the active site, but they differ in the choice of starter molecule and the number of condensation reactions.


Pssm-ID: 238427 [Multi-domain]  Cd Length: 361  Bit Score: 343.44  E-value: 4.06e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286   1 MPKIISVGFGVPPYELTQQDTLLFAKELFSES--FKDINRLLTVFQNGQIEKRNFAKD--LSWFQE----DHTFEEKNDA 72
Cdd:cd00831    1 AATILAIGTAVPPHRVPQSELVDFYRRLFSSDhlPELKEKLKRLCAKTGIETRYLVLPggEETYAPrpemSPSLDERNDI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  73 FIECAVELGTKAIEECLTNkdyvsTPLPCGEIDAIFYVSTSGVATPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLS 152
Cdd:cd00831   81 ALEEARELAEEAARGALDE-----AGLRPSDIDHLVVNTSTGNPTPSLDAMLINRLGLRPDVKRYNLGGMGCSAGAIALD 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 153 RAYEYCKAFPRAKVLVLSVELCSLTFQRNDrSKSNLIGTSLFADGVAAALVAGDEADitFSRSKSFPYILHTQSTLMPNS 232
Cdd:cd00831  156 LAKDLLEANPGARVLVVSTELCSLWYRGPD-HRSMLVGNALFGDGAAAVLLSNDPRD--RRRERPLFELVRAASTLLPDS 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 233 EDVMGWEIKNDGLFVVFSKDIPTIIDSWLGGEVESFLQTQ--NLTSRDLKHFVAHPGGKKVLEAYVSTLSLNENMIADSL 310
Cdd:cd00831  233 EDAMGWHLGEEGLTFVLSRDVPRLVEKNLERVLRKLLARLgiGLFKLAFDHWCVHPGGRAVLDAVEKALGLSPEDLEASR 312

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 654964286 311 DVLKNHGNMSSATVLYVLDRFMKKEIPSK-EYGLLTALGPGFSSEMLLL 358
Cdd:cd00831  313 MVLRRYGNMSSSSVLYVLAYMEAKGRVKRgDRGLLIAFGPGFTCESAVW 361
PLN03169 PLN03169
chalcone synthase family protein; Provisional
 70-358 5.65e-31

chalcone synthase family protein; Provisional


Pssm-ID: 215612 [Multi-domain]  Cd Length: 391  Bit Score: 120.96  E-value: 5.65e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  70 NDAFIECAVELGTKAIEECltnkdyvstPLPCGEIDAIFYVSTSGVATPSIEARIMNKLAFSDHTKRIPIWGLGCAGGAS 149
Cdd:PLN03169 103 NEAVTQMAVEASLACIKEW---------GRPVSDITHLVYVSSSEARLPGGDLYLAKQLGLSPDVQRVMLYFLGCSGGVA 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 150 GLSRAYEYCKAFPRAKVLVLSVELCSLTFQ--RNDRSkSNLIGTSLFADGVAAALVAGDEADITFSrsksfPYI-LHT-- 224
Cdd:PLN03169 174 GLRVAKDIAENNPGSRVLLTTSETTILGFRppSPDRP-YDLVGAALFGDGAAAVIIGADPIPVSES-----PFFeLHTai 247

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 225 QSTLmPNSEDVMGWEIKNDGLFVVFSKDIPTIIDSwlggEVESFLQT----QNLTSRDL-KHFVA-HPGGKKVLEAYVST 298
Cdd:PLN03169 248 QQFL-PGTEKTIDGRLTEEGINFKLGRELPQKIED----NIEGFCKKlmkkAGLVEKDYnDLFWAvHPGGPAILNRLEKK 322

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 654964286 299 LSLNENMIADSLDVLKNHGNMSSATVLYVLDrFMKKEI-----PSKEYGLLTALGPGFSSEMLLL 358
Cdd:PLN03169 323 LKLAPEKLECSRRALMDYGNVSSNTIVYVLE-YMREELkkkgeEDEEWGLILAFGPGITFEGILA 386
PLN03172 PLN03172
chalcone synthase family protein; Provisional
 100-358 3.52e-27

chalcone synthase family protein; Provisional


Pssm-ID: 178716  Cd Length: 393  Bit Score: 110.53  E-value: 3.52e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 100 PCGEIDAIFYVSTSGVATPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLSRAYEYCKAFPRAKVLVLSVELCSLTFQ 179
Cdd:PLN03172 120 PKSKITHLVFCTTSGVDMPGADYQLTKLLGLKPSVKRFMMYQQGCFAGGTVLRLAKDLAENNAGSRVLVVCSEITAVTFR 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 180 -RNDRSKSNLIGTSLFADGvAAALVAGDEADITFSRSksFPYILHTQSTLMPNSEDVMGWEIKNDGLFVVFSKDIPTIID 258
Cdd:PLN03172 200 gPSDTHLDSLVGQALFGDG-AAAVIIGADPDTKIERP--LFEIVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLIS 276

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 259 SWLGGEVESFLQTQNLTSRDLKHFVAHPGGKKVLEAYVSTLSLNENMIADSLDVLKNHGNMSSATVLYVLDRFMKKEIPS 338
Cdd:PLN03172 277 KNIEKSLVEAFAPIGINDWNSIFWIAHPGGPAILDQVEIKLDLKEEKLRATRHVLSDYGNMSSACVLFILDEMRKKSIEE 356

                        250       260
                 ....*....|....*....|....*...
gi 654964286 339 K--------EYGLLTALGPGFSSEMLLL 358
Cdd:PLN03172 357 GkgstgeglEWGVLFGFGPGLTVETVVL 384
PLN03173 PLN03173
chalcone synthase; Provisional
 100-358 6.01e-27

chalcone synthase; Provisional


Pssm-ID: 178717 [Multi-domain]  Cd Length: 391  Bit Score: 110.17  E-value: 6.01e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 100 PCGEIDAIFYVSTSGVATPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLSRAYEYCKAFPRAKVLVLSVELCSLTFQ 179
Cdd:PLN03173 120 PKSKITHLVFCTTSGVDMPGADYQLTKLLGLRSSVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFR 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 180 -RNDRSKSNLIGTSLFADGVAAALVAGDEadiTFSRSKSFPYILHTQSTLMPNSEDVMGWEIKNDGLFVVFSKDIPTIID 258
Cdd:PLN03173 200 gPSDTHLDSLVGQALFGDGAAAIIIGSDP---VLGVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLIS 276

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 259 SWLGGEVESFLQTQNLTSRDLKHFVAHPGGKKVLEAYVSTLSLNENMIADSLDVLKNHGNMSSATVLYVLDRFMKKEIPS 338
Cdd:PLN03173 277 KNVEKSLTEAFKPLGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSAED 356

                        250       260
                 ....*....|....*....|....*...
gi 654964286 339 K--------EYGLLTALGPGFSSEMLLL 358
Cdd:PLN03173 357 GlkstgeglEWGVLFGFGPGLTVETVVL 384
PLN03170 PLN03170
chalcone synthase; Provisional
 100-358 7.12e-27

chalcone synthase; Provisional


Pssm-ID: 178714 [Multi-domain]  Cd Length: 401  Bit Score: 109.80  E-value: 7.12e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 100 PCGEIDAIFYVSTSGVATPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLSRAYEYCKAFPRAKVLVLSVELCSLTFQ 179
Cdd:PLN03170 124 PKSKITHLVFCTTSGVDMPGADYQLTKMLGLRPSVNRLMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEITAVTFR 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 180 RNDRSK-SNLIGTSLFADGVAAALVAGDEADITfsrSKSFPYILHTQSTLMPNSEDVMGWEIKNDGLFVVFSKDIPTIID 258
Cdd:PLN03170 204 GPSESHlDSMVGQALFGDGAAAVIVGADPDERV---ERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLIS 280

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 259 SWLGGEVESFLQTQNLTSRDLKHFVAHPGGKKVLEAYVSTLSLNENMIADSLDVLKNHGNMSSATVLYVLDRFMKKEIPS 338
Cdd:PLN03170 281 KNIERSLEEAFKPLGITDYNSIFWVAHPGGPAILDQVEAKVGLEKERMRATRHVLSEYGNMSSACVLFILDEMRKRSAED 360

                        250       260
                 ....*....|....*....|....*...
gi 654964286 339 K--------EYGLLTALGPGFSSEMLLL 358
Cdd:PLN03170 361 GqattgegfDWGVLFGFGPGLTVETVVL 388
PLN03168 PLN03168
chalcone synthase; Provisional
 77-358 1.72e-26

chalcone synthase; Provisional


Pssm-ID: 178712 [Multi-domain]  Cd Length: 389  Bit Score: 108.59  E-value: 1.72e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  77 AVELGTKAIEECLTNKDyvstplpcgEIDAIFYVSTSGVATPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLSRAYE 156
Cdd:PLN03168 105 AAEAAQKAIKEWGGRKS---------DITHIVFATTSGVNMPGADHALAKLLGLKPTVKRVMMYQTGCFGGASVLRVAKD 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 157 YCKAFPRAKVLVLSVELCSLTFQR-NDRSKSNLIGTSLFADGVAAALVAGDEADitfSRSKSFPYILHTQSTLMPNSEDV 235
Cdd:PLN03168 176 LAENNKGARVLAVASEVTAVTYRApSENHLDGLVGSALFGDGAGVYVVGSDPKP---EVEKALFEVHWAGETILPESDGA 252

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 236 MGWEIKNDGLFVVFSKDIPTIIDSWLGGEVESFLQTQNLTSRDLKHFVAHPGGKKVLEAYVSTLSLNENMIADSLDVLKN 315
Cdd:PLN03168 253 IDGHLTEAGLIFHLMKDVPGLISKNIEKFLNEARKCVGSPDWNEMFWAVHPGGPAILDQVEAKLKLTKDKMQGSRDILSE 332

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 654964286 316 HGNMSSATVLYVLDRFMKKEIP--------SKEYGLLTALGPGFSSEMLLL 358
Cdd:PLN03168 333 FGNMSSASVLFVLDQIRQRSVKmgastlgeGSEFGFFIGFGPGLTLEVLVL 383
PLN03171 PLN03171
chalcone synthase-like protein; Provisional
 71-358 8.94e-24

chalcone synthase-like protein; Provisional


Pssm-ID: 178715 [Multi-domain]  Cd Length: 399  Bit Score: 101.23  E-value: 8.94e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  71 DAFIECAVELGTKAIEECltnkdyvstPLPCGEIDAIFYVSTSGVATPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASG 150
Cdd:PLN03171 106 DAVPELAAEAAKKAIAEW---------GRPAADITHLVVTTNSGAHIPGVDFRLVPLLGLRPSVRRTMLHLNGCFAGAAA 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 151 LSRAYEYCKAFPRAKVLVLSVELCSLTFQRNDRSK-SNLIGTSLFADGVAAALVAGDEADItfsrSKSFPYILHTQSTLM 229
Cdd:PLN03171 177 LRLAKDLAENNRGARVLVVAAEITLLLFNGPDEGCfQTLLNQGLFGDGAAAVIVGADADAA----ERPLFEIVSAAQAII 252

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 230 PNSEDVMGWEIKNDGL-FVVFSKDIPTIIdswlGGEVESFLQTQ---------NLTSRDLkHFVAHPGGKKVLEAYVSTL 299
Cdd:PLN03171 253 PESDDAINMHFTEGGLdGNIGTRQVPGLI----GDNIERCLLDAfapllggdgGAEWNDL-FWAVHPGSSAILDQVDAAL 327

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 654964286 300 SLNENMIADSLDVLKNHGNMSSATVLYVLD---RFMKK-----EIPskEYGLLTALGPGFSSEMLLL 358
Cdd:PLN03171 328 GLEPEKLAASRRVLSDYGNMFGATVIFALDelrRQMEEaaaagAWP--ELGVMMAFGPGLTVDAMLL 392
KAS_III cd00830
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty ...
 3-358 6.07e-18

Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.


Pssm-ID: 238426 [Multi-domain]  Cd Length: 320  Bit Score: 83.36  E-value: 6.07e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286   3 KIISVGFGVPPYELTQQDtllFAKELFSESfkdinrlLTVFQNGQIEKRNFAKDLswfqedhtfeekndafiECAVELGT 82
Cdd:cd00830    3 RILGIGSYLPERVVTNDE---LEKRLDTSD-------EWIRTRTGIRERRIADPG-----------------ETTSDLAV 55

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  83 KAIEECLTNkdyvsTPLPCGEIDAIFYVSTSG-VATPSIEARIMNKL------AFsDHTkripiwgLGCAGGASGLSRAY 155
Cdd:cd00830   56 EAAKKALED-----AGIDADDIDLIIVATSTPdYLFPATACLVQARLgaknaaAF-DIN-------AACSGFLYGLSTAA 122

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 156 EYCKAFPRAKVLVLSVELCSLTFQRNDRSksnligTS-LFADGVAAALV-AGDEAD-ITFSRSKSFP------YILHTQS 226
Cdd:cd00830  123 GLIRSGGAKNVLVVGAETLSRILDWTDRS------TAvLFGDGAGAVVLeATEEDPgILDSVLGSDGsgadllTIPAGGS 196

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 227 TLMPNSEDVMGWEIKNDG--LFVVFSKDIPTIIdswlggevESFLQTQNLTSRDLKHFVAHPGGKKVLEAYVSTLSLNEN 304
Cdd:cd00830  197 RSPFEDAEGGDPYLVMDGreVFKFAVRLMPESI--------EEALEKAGLTPDDIDWFVPHQANLRIIEAVAKRLGLPEE 268

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 654964286 305 MIADSLDvlkNHGNMSSATVLYVLDRFMKK-EIPSKEYGLLTALGPGFSSEMLLL 358
Cdd:cd00830  269 KVVVNLD---RYGNTSAASIPLALDEAIEEgKLKKGDLVLLLGFGAGLTWGAALL 320
Chal_sti_synt_C pfam02797
Chalcone and stilbene synthases, C-terminal domain; This domain of chalcone synthase is ...
 227-358 1.63e-17

Chalcone and stilbene synthases, C-terminal domain; This domain of chalcone synthase is reported to be structurally similar to domains in thiolase and beta-ketoacyl synthase. The differences in activity are accounted for by differences in the N-terminal domain.


Pssm-ID: 397089  Cd Length: 151  Bit Score: 78.65  E-value: 1.63e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  227 TLMPNSEDVMGWEIKNDGLFVVFSKDIPTIIDSwlggEVESFLQT--QNLTSRDLKH--FVAHPGGKKVLEAYVSTLSLN 302
Cdd:pfam02797   8 TFLPNTDGVIDGHLTEEGLTFHLGRDVPQKIEE----NIEEFLKKafEPLGISEWNSlfWIVHPGGPAILDRVETKLGLE 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 654964286  303 ENMIADSLDVLKNHGNMSSATVLYVLDRFMKKEI--------PSKEYGLLTALGPGFSSEMLLL 358
Cdd:pfam02797  84 PEKLEASRRALMDYGNVSSATVLFILDEMRKKSLkkglattgEGLDWGVLLAFGPGLTFETVVL 147
Chal_sti_synt_N pfam00195
Chalcone and stilbene synthases, N-terminal domain; The C-terminal domain of Chalcone synthase ...
 65-206 1.58e-15

Chalcone and stilbene synthases, N-terminal domain; The C-terminal domain of Chalcone synthase is reported to be structurally similar to domains in thiolase and beta-ketoacyl synthase. The differences in activity are accounted for by differences in this N-terminal domain.


Pssm-ID: 395142  Cd Length: 225  Bit Score: 74.89  E-value: 1.58e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286   65 TFEEKNDAFIECAVELGTKAIEECLtnKDYVStplPCGEIDAIFYVSTSGVATPSIEARIMNKLAFSDHTKRIPIWGLGC 144
Cdd:pfam00195  87 SLDARLEIANAEVPELGAEAALKAI--KEWGQ---PKSKITHLVFCTTSGVRMPGADYQLAKLLGLRPSVKRVMLYFQGC 161

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 654964286  145 AGGASGLSRAYEYCKAFPRAKVLVLSVELCSLTFQ-RNDRSKSNLIGTSLFADGVAAALVAGD 206
Cdd:pfam00195 162 YGGATVLRTAKDIAENNPGARVLVVCSEITVLGFRgPSKDRLDSLVGAALFGDGAAAVIIGAD 224
PRK12879 PRK12879
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed
 75-360 1.81e-14

3-oxoacyl-(acyl carrier protein) synthase III; Reviewed


Pssm-ID: 237245 [Multi-domain]  Cd Length: 325  Bit Score: 73.36  E-value: 1.81e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  75 ECAVELGTKAIEECLTnkDYVSTPlpcGEIDAIFYVSTSGV-ATPSIEARIMNKLafsdHTKRIPIWGL--GCAGGASGL 151
Cdd:PRK12879  51 EYTSDLAIKAAERALA--RAGLDA---EDIDLIIVATTTPDyLFPSTASQVQARL----GIPNAAAFDInaACAGFLYGL 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 152 SRAyeycKAFPRA----KVLVLSVELCSLTFQRNDRSksnligTS-LFADGVAAALVAGDEADITF------SRSKSFPY 220
Cdd:PRK12879 122 ETA----NGLITSglykKVLVIGAERLSKVTDYTDRT------TCiLFGDGAGAVVLEATENEPGFidyvlgTDGDGGDI 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 221 ILHTQ-STLMPNSEDVMGWEIKNDGLfVVFSKDIPTIidswlGGEVESFLQTQNLTSRDLKHFVAHPGGKKVLEAYVSTL 299
Cdd:PRK12879 192 LYRTGlGTTMDRDALSGDGYIVQNGR-EVFKWAVRTM-----PKGARQVLEKAGLTKDDIDWVIPHQANLRIIESLCEKL 265

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 654964286 300 SLNENMIADSLDvlkNHGNMSSATVLYVLDRFMKK-EIPSKEYGLLTALGPGFSSEMLLLEW 360
Cdd:PRK12879 266 GIPMEKTLVSVE---YYGNTSAATIPLALDLALEQgKIKPGDTLLLYGFGAGLTWAALLVKW 324
FabH COG0332
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ...
 75-360 2.38e-14

3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440101 [Multi-domain]  Cd Length: 323  Bit Score: 72.83  E-value: 2.38e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  75 ECAVELGTKAIEECLTNKDYvsTPlpcGEIDAIFYVSTSG-VATPSIEARIMNKLafsdHTKRIPIW--GLGCAGGASGL 151
Cdd:COG0332   49 ETTSDLAVEAARKALEAAGI--DP---EDIDLIIVATVTPdYLFPSTACLVQHKL----GAKNAAAFdiNAACSGFVYAL 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 152 SRAYEYCKAfPRAK-VLVLSVELCSLTFQRNDRSksnligTS-LFADGVAAALVAGDEADITFSRSK-----SFPYILHT 224
Cdd:COG0332  120 SVAAALIRS-GQAKnVLVVGAETLSRIVDWTDRS------TCvLFGDGAGAVVLEASEEGPGILGSVlgsdgSGADLLVV 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 225 --QSTLMPNSEDVMGWE-IKNDG--LFVVFSKDIPTIIdswlggevESFLQTQNLTSRDLKHFVAHPGGKKVLEAYVSTL 299
Cdd:COG0332  193 paGGSRNPPSPVDEGDHyLRMDGreVFKFAVRNLPEVI--------REALEKAGLTLDDIDWFIPHQANLRIIEAVAKRL 264

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 654964286 300 SLNENMIADSLDvlkNHGNMSSATVLYVLDRFMK-KEIPSKEYGLLTALGPGFSSEMLLLEW 360
Cdd:COG0332  265 GLPEEKVVVNID---RYGNTSAASIPLALDEALReGRIKPGDLVLLAGFGAGLTWGAAVLRW 323
init_cond_enzymes cd00827
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ...
 4-358 5.37e-12

"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.


Pssm-ID: 238423 [Multi-domain]  Cd Length: 324  Bit Score: 65.92  E-value: 5.37e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286   4 IISVGFGVPPYELTQQDtllFAKELFSESFKdinrlltvFQNGqIEKRNFAKDlswfqedhtfeekndafIECAVELGTK 83
Cdd:cd00827    4 IEAIGAYLPRYRVDNEE---LAEGLGVDPGK--------YTTG-IGQRHMAGD-----------------DEDVPTMAVE 54

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  84 AIEECLTNKDyvstpLPCGEIDAIFYVSTSGV-ATPSIEARIMNKLAFSDhtkripIWGL----GCAGGASGLSRAYEYC 158
Cdd:cd00827   55 AARRALERAG-----IDPDDIGLLIVATESPIdKGKSAATYLAELLGLTN------AEAFdlkqACYGGTAALQLAANLV 123

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 159 KAFPRAKVLVlsveLCSLTFQRNDRSKSNLIGTslFADGVAAALVaGDEADITFSRSKSfpYILHTQSTLMPNSEDVMG- 237
Cdd:cd00827  124 ESGPWRYALV----VASDIASYLLDEGSALEPT--LGDGAAAMLV-SRNPGILAAGIVS--THSTSDPGYDFSPYPVMDg 194

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 238 --WEIKNDGLFVVFSKDIP-TIIDSWLGGEVESFLQ---TQNLTSRDLKHFVAH-PGGKKVLEAYVSTLSLN-ENMIADS 309
Cdd:cd00827  195 gyPKPCKLAYAIRLTAEPAgRAVFEAAHKLIAKVVRkalDRAGLSEDIDYFVPHqPNGKKILEAVAKKLGGPpEKASQTR 274

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 654964286 310 LDVLKNHGNMSSATVLYVLDRFMK-KEIPSKEYGLLTALGPGFSSEMLLL 358
Cdd:cd00827  275 WILLRRVGNMYAASILLGLASLLEsGKLKAGDRVLLFSYGSGFTAEAFVL 324
ACP_syn_III_C pfam08541
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on ...
 269-360 1.30e-09

3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.41, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.


Pssm-ID: 430060  Cd Length: 90  Bit Score: 54.43  E-value: 1.30e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  269 LQTQNLTSRDLKHFVAHPGGKKVLEAYVSTLSLNENMIADSLDvlkNHGNMSSATVLYVLDRFMKK-EIPSKEYGLLTAL 347
Cdd:pfam08541   1 LEKAGLTPEDIDWFVPHQANLRIIDAVAKRLGLPPEKVVVNLD---EYGNTSAASIPLALDEAVEEgKLKPGDLVLLVGF 77

                          90
                  ....*....|...
gi 654964286  348 GPGFSSEMLLLEW 360
Cdd:pfam08541  78 GAGLTWGAALLRW 90
PLN00415 PLN00415
3-ketoacyl-CoA synthase
 118-361 6.95e-08

3-ketoacyl-CoA synthase


Pssm-ID: 177808  Cd Length: 466  Bit Score: 53.93  E-value: 6.95e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 118 PSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLSRAYEYCKAFPRAKVLVLSVELCSLTFQR-NDRSKsnLIGTSLFAD 196
Cdd:PLN00415 170 PSLSSMIVNRYKLKTDVKTYNLSGMGCSAGAISVDLATNLLKANPNTYAVIVSTENMTLSMYRgNDRSM--LVPNCLFRV 247

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 197 GVAAALVAGDEADITFSRSKsFPYILHTQS-------TLMPNSEDVMGWeikndgLFVVFSKDIPTIIDSWLGGEVES-- 267
Cdd:PLN00415 248 GGAAVMLSNRSQDRVRSKYE-LTHIVRTHKgssdkhyTCAEQKEDSKGI------VGVALSKELTVVAGDTLKTNLTAlg 320

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 268 --------------FLQTQNLTSRDL-----------KHFVAHPGGKKVLEAYVSTLSLNENMIADSLDVLKNHGNMSSA 322
Cdd:PLN00415 321 plvlplseklrfilFLVKSKLFRLKVspyvpdfklcfKHFCIHAGGRALLDAVEKGLGLSEFDLEPSRMTLHRFGNTSSS 400

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 654964286 323 TVLYVLDRFMKK-EIPSKEYGLLTALGPGFSSEMLLleWR 361
Cdd:PLN00415 401 SLWYELAYVEAKcRVKRGDRVWQLAFGSGFKCNSIV--WR 438
PLN02854 PLN02854
3-ketoacyl-CoA synthase
 117-328 3.84e-07

3-ketoacyl-CoA synthase


Pssm-ID: 215459  Cd Length: 521  Bit Score: 51.88  E-value: 3.84e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 117 TPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLSRAYEYCKAFPRAKVLVLSVELCSLT-FQRNDRSKsnLIGTSLFA 195
Cdd:PLN02854 223 TPSLSAMIVNHYKLRTDIKSYNLGGMGCSAGLISIDLANDLLKANPNSYAVVVSTENITLNwYFGNDRSM--LLCNCIFR 300

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 196 DGVAAALVAGDEADitfsRSKSFPYILHTQST----------LMPNSED---VMGWEIKNDgLFVVFSKDIPTIIDSwLG 262
Cdd:PLN02854 301 MGGAAVLLSNKARD----RKRSKYQLVHTVRThkgaddknynCVYQREDdkgTIGVSLARE-LMAVAGDALKTNITT-LG 374

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 263 GEV----ESFLQTQNLTSRDL----------------KHFVAHPGGKKVLEAYVSTLSLNENMIADSLDVLKNHGNMSSA 322
Cdd:PLN02854 375 PLVlplsEQFMFFVTLVRRKLlkakvkpyipdfklafEHFCIHAGGRAVLDELQKNLQLSDWHMEPSRMTLHRFGNTSSS 454


                 ....*.
gi 654964286 323 TVLYVL 328
Cdd:PLN02854 455 SLWYEL 460
PLN02932 PLN02932
3-ketoacyl-CoA synthase
 117-328 1.00e-06

3-ketoacyl-CoA synthase


Pssm-ID: 178520  Cd Length: 478  Bit Score: 50.42  E-value: 1.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 117 TPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLSRAYEYCKAFPRAKVLVLSVELCSLTFQRNdRSKSNLIGTSLFAD 196
Cdd:PLN02932 183 TPSLSSILVNKFKLRDNIKSLNLGGMGCSAGVIAIDAAKSLLQVHRNTYALVVSTENITQNLYLG-NNKSMLVTNCLFRI 261

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 197 GVAAALVAGDEADitfsRSKSFPYILHT---QSTLMPNSEDVMGWEIKNDGLF-VVFSKDIPTIIDSWLGGEVES----- 267
Cdd:PLN02932 262 GGAAILLSNRSRD----RKRAKYELVHTvrvHTGADDRSYECATQEEDEDGIVgVSLSKNLPMVAARTLKINIATlgplv 337

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 268 ------------FLQTQNLTSR------DLK----HFVAHPGGKKVLEAYVSTLSLNENMIADSLDVLKNHGNMSSATVL 325
Cdd:PLN02932 338 lplsekfhffvrFVKKKFFNPKlkhyipDFKlafeHFCIHAGGRALIDEMEKNLHLTPLDVEASRMTLHRFGNTSSSSIW 417


                 ...
gi 654964286 326 YVL 328
Cdd:PLN02932 418 YEL 420
FAE1_CUT1_RppA pfam08392
FAE1/Type III polyketide synthase-like protein; The members of this family are described as ...
 117-216 1.22e-06

FAE1/Type III polyketide synthase-like protein; The members of this family are described as 3-ketoacyl-CoA synthases, type III polyketide synthases, fatty acid elongases and fatty acid condensing enzymes, and are found in both prokaryotic and eukaryotic (mainly plant) species. The region featured in this family contains the active site residues, as well as motifs involved in substrate binding.


Pssm-ID: 429970  Cd Length: 290  Bit Score: 49.55  E-value: 1.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  117 TPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLSRAYEYCKAFPRAKVLVLSVELCSLTFQR-NDRSKsnLIGTSLFA 195
Cdd:pfam08392 118 TPSLSAMIVNRYKLRSDIKSYNLSGMGCSAGLISIDLAKNLLQVHPNTYALVVSTENITPNWYFgNDRSM--LLPNCLFR 195

                          90       100
                  ....*....|....*....|.
gi 654964286  196 DGVAAALVAGDEADitFSRSK 216
Cdd:pfam08392 196 MGGAAVLLSNRPAD--RRRAK 214
PLN02377 PLN02377
3-ketoacyl-CoA synthase
 117-328 7.39e-06

3-ketoacyl-CoA synthase


Pssm-ID: 166018  Cd Length: 502  Bit Score: 47.71  E-value: 7.39e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 117 TPSIEARIMNKLAFSDHTKRIPIWGLGCAGGASGLSRAYEYCKAFPRAKVLVLSVELCSLTFQRNDRsKSNLIGTSLFAD 196
Cdd:PLN02377 207 TPSLSAMIVNKYKLRGNIRSFNLGGMGCSAGVIAVDLAKDMLQVHRNTYAVVVSTENITQNWYFGNK-KSMLIPNCLFRV 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 197 GVAAALVAGDEADITFSR--------------SKSFPYILHTQS----TLMPNSEDVM---GWEIKND-----GLFVVFS 250
Cdd:PLN02377 286 GGSAVLLSNKSRDKRRSKyklvhvvrthrgadDKAFRCVYQEQDdagkTGVSLSKDLMaiaGEALKTNittlgPLVLPIS 365

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 251 KDI----PTIIDSWLGGEVESFLQTQNLTsrdLKHFVAHPGGKKVLEAYVSTLSLNENMIADSLDVLKNHGNMSSATVLY 326
Cdd:PLN02377 366 EQLlffaTLVVKKLFNKKMKPYIPDFKLA---FDHFCIHAGGRAVIDELEKNLQLLPVHVEASRMTLHRFGNTSSSSIWY 442


                 ..
gi 654964286 327 VL 328
Cdd:PLN02377 443 EL 444
fabH CHL00203
3-oxoacyl-acyl-carrier-protein synthase 3; Provisional
 144-361 1.40e-05

3-oxoacyl-acyl-carrier-protein synthase 3; Provisional


Pssm-ID: 164577 [Multi-domain]  Cd Length: 326  Bit Score: 46.48  E-value: 1.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 144 CAGGASGLSRAYEYCKAFPRAKVLVLSVELCSLTFQRNDRSKsnligTSLFADGVAAALVAG--DEADITFSRSKSFPYI 221
Cdd:CHL00203 111 CSGFILALVTATQFIQNGSYKNILVVGADTLSKWIDWSDRKT-----CILFGDGAGAAIIGAsyENSILGFKLCTDGKLN 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 222 LHTQSTLMP-NSEDVMGWEI------------KNDGLFVVFSkdIPTIIdswlggevESFLQTQNLTSRDLKHFVAHPGG 288
Cdd:CHL00203 186 SHLQLMNKPvNNQSFGTTKLpqgqyqsismngKEVYKFAVFQ--VPAVI--------IKCLNALNISIDEVDWFILHQAN 255

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 654964286 289 KKVLEAYVSTLSL-NENMIADsldvLKNHGNMSSATVLYVLDRFMK-KEIPSKEYGLLTALGPGFSSEMLLLEWR 361
Cdd:CHL00203 256 KRILEAIANRLSVpNSKMITN----LEKYGNTSAASIPLALDEAIQnNKIQPGQIIVLSGFGAGLTWGAIVLKWK 326
decarbox_cond_enzymes cd00825
decarboxylating condensing enzymes; Family of enzymes that catalyze the formation of a new ...
 143-358 1.85e-05

decarboxylating condensing enzymes; Family of enzymes that catalyze the formation of a new carbon-carbon bond by a decarboxylating Claisen-like condensation reaction. Members are involved in the synthesis of fatty acids and polyketides, a diverse group of natural products. Both pathways are an iterative series of additions of small carbon units, usually acetate, to a nascent acyl group. There are 2 classes of decarboxylating condensing enzymes, which can be distinguished by sequence similarity, type of active site residues and type of primer units (acetyl CoA or acyl carrier protein (ACP) linked units).


Pssm-ID: 238421 [Multi-domain]  Cd Length: 332  Bit Score: 46.09  E-value: 1.85e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 143 GCAGGASGLSRAYEYCKAFPRAKVLVLSVEL----CSLTFQ---------RNDRSKSNLIGTSLFADGvAAALVAGDEAD 209
Cdd:cd00825   95 ACAGSLHALSLAADAVQNGKQDIVLAGGSEElaapMDCEFDamgalstpeKASRTFDAAADGFVFGDG-AGALVVEELEH 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 210 ITFSRSKSFPYILHTQSTLMPNSEdvmgweikndGLFVVFSKDIPTIIDSWLGGevesflqtQNLTSRDLKHFVAHPGGK 289
Cdd:cd00825  174 ALARGAHIYAEIVGTAATIDGAGM----------GAFAPSAEGLARAAKEALAV--------AGLTVWDIDYLVAHGTGT 235

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 290 KVLEAYVSTLSLNENMIAD--SLDVLKNHGNMSSATVLYVLDRFMK----KEIPSKEY---------------------- 341
Cdd:cd00825  236 PIGDVKELKLLRSEFGDKSpaVSATKAMTGNLSSAAVVLAVDEAVLmlehGFIPPSIHieeldeaglnivtettprelrt 315

                        250
                 ....*....|....*..
gi 654964286 342 GLLTALGPGFSSEMLLL 358
Cdd:cd00825  316 ALLNGFGLGGTNATLVL 332
PRK09352 PRK09352
beta-ketoacyl-ACP synthase 3;
75-352 2.93e-05

beta-ketoacyl-ACP synthase 3;


Pssm-ID: 236475 [Multi-domain]  Cd Length: 319  Bit Score: 45.45  E-value: 2.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286  75 ECAVELGTKAIEECLTNkdyvsTPLPCGEIDAIFyVSTS--GVATPSIEARIMNKL------AFsDHTKripiwglGCAG 146
Cdd:PRK09352  50 ETTSDLATEAAKKALEA-----AGIDPEDIDLII-VATTtpDYAFPSTACLVQARLgaknaaAF-DLSA-------ACSG 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 147 GASGLSRAyeycKAFPRA----KVLVLSVElcslTFQR----NDRSksnligTS-LFADGVAAALV-AGDEADITfsrsk 216
Cdd:PRK09352 116 FVYALSTA----DQFIRSgaykNVLVIGAE----KLSRivdwTDRS------TCvLFGDGAGAVVLgASEEPGIL----- 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654964286 217 sfPYILHTQST-----LMPNSEDVMGWE---IKNDG--LFVVFSKDIPTIIdswlggevESFLQTQNLTSRDLKHFVAHP 286
Cdd:PRK09352 177 --STHLGSDGSygdllYLPGGGSRGPASpgyLRMEGreVFKFAVRELAKVA--------REALEAAGLTPEDIDWLVPHQ 246

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 654964286 287 GGKKVLEAYVSTLSLNENMIADSLDvlkNHGNMSSATVLYVLDRFMKK-EIPSKEYGLLTALGPGFS 352
Cdd:PRK09352 247 ANLRIIDATAKKLGLPMEKVVVTVD---KYGNTSAASIPLALDEAVRDgRIKRGDLVLLEGFGGGLT 310
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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