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Conserved domains on  [gi|655374811|ref|WP_028780310|]
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MULTISPECIES: transcriptional repressor AgaR [Shewanella]

Protein Classification

DeoR/GlpR family DNA-binding transcription regulator( domain architecture ID 11442564)

DeoR/GlpR family DNA-binding transcription regulator is a helix-turn-helix type transcriptional regulator that may be involved in sugar metabolism

Gene Ontology:  GO:0003700|GO:0003677
PubMed:  15808743

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AgaR super family cl48989
transcriptional repressor AgaR;
4-251 4.28e-119

transcriptional repressor AgaR;


The actual alignment was detected with superfamily member NF040755:

Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 340.40  E-value: 4.28e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   4 LNTIERQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGAMVNSDLIR--ELSLKEKGHCYSAL 81
Cdd:NF040755   2 KGTSERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALINDGFIPgaEPSVEDKSRLNTAV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811  82 KQELGKVAASLVNDGDRLLLDSGTTTQQVAANLLEHQDLIVMTNGLNIATELARSDDVEVMLTGGLLRKKSMSFYGSIAE 161
Cdd:NF040755  82 KRLIAAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVMTNGLNVANELLEAEGVEVLMTGGHLRRQSLSFYGDQAE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811 162 KSLRDYNFNKLILGVDGFDLKTGLTTHFEKEASLNRMMCEIASEIIVVTDSSKFDQQAFHVICASRQIQQLVTDSGIPER 241
Cdd:NF040755 162 QSLQNYHFDKLFLGVDGFDLERGITTHNEDEARLNRRMCEVAERIIAVTDSSKFGRSSLHKIRDTGRIDTLITDSGIPEE 241

                        250
                 ....*....|
gi 655374811 242 YVEELTKQGV 251
Cdd:NF040755 242 YLQGLRKLGV 251
 
Name Accession Description Interval E-value
AgaR NF040755
transcriptional repressor AgaR;
4-251 4.28e-119

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 340.40  E-value: 4.28e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   4 LNTIERQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGAMVNSDLIR--ELSLKEKGHCYSAL 81
Cdd:NF040755   2 KGTSERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALINDGFIPgaEPSVEDKSRLNTAV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811  82 KQELGKVAASLVNDGDRLLLDSGTTTQQVAANLLEHQDLIVMTNGLNIATELARSDDVEVMLTGGLLRKKSMSFYGSIAE 161
Cdd:NF040755  82 KRLIAAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVMTNGLNVANELLEAEGVEVLMTGGHLRRQSLSFYGDQAE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811 162 KSLRDYNFNKLILGVDGFDLKTGLTTHFEKEASLNRMMCEIASEIIVVTDSSKFDQQAFHVICASRQIQQLVTDSGIPER 241
Cdd:NF040755 162 QSLQNYHFDKLFLGVDGFDLERGITTHNEDEARLNRRMCEVAERIIAVTDSSKFGRSSLHKIRDTGRIDTLITDSGIPEE 241

                        250
                 ....*....|
gi 655374811 242 YVEELTKQGV 251
Cdd:NF040755 242 YLQGLRKLGV 251
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 5-257 1.55e-103

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 300.90  E-value: 1.55e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   5 NTIERQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGAMVNSDLIRELSLKEKGHCYSALKQE 84
Cdd:COG1349    2 LAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNAEEKRA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811  85 LGKVAASLVNDGDRLLLDSGTTTQQVAANLLEHQDLIVMTNGLNIATELARSDDVEVMLTGGLLRKKSMSFYGSIAEKSL 164
Cdd:COG1349   82 IARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEAL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811 165 RDYNFNKLILGVDGFDLKTGLTTHFEKEASLNRMMCEIASEIIVVTDSSKFDQQAFHVICASRQIQQLVTDSGIPERYVE 244
Cdd:COG1349  162 RRFRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPELLE 241

                        250
                 ....*....|...
gi 655374811 245 ELTKQGVQLHLID 257
Cdd:COG1349  242 ALEEAGVEVIVAE 254
PRK09802 PRK09802
DeoR family transcriptional regulator;
4-256 2.20e-86

DeoR family transcriptional regulator;


Pssm-ID: 182086 [Multi-domain]  Cd Length: 269  Bit Score: 258.25  E-value: 2.20e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   4 LNTIERQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGAMV--NSDLIRELSLKEKGHCYSAL 81
Cdd:PRK09802  13 TGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALIcdSTTPSVEPSVEDKSALNTAM 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811  82 KQELGKVAASLVNDGDRLLLDSGTTTQQVAANLLEHQDLIVMTNGLNIATELARSDDVEVMLTGGLLRKKSMSFYGSIAE 161
Cdd:PRK09802  93 KRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAE 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811 162 KSLRDYNFNKLILGVDGFDLKTGLTTHFEKEASLNRMMCEIASEIIVVTDSSKFDQQAFHVICASRQIQQLVTDSGIPER 241
Cdd:PRK09802 173 QSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPAD 252

                        250
                 ....*....|....*
gi 655374811 242 YVEELTKQGVQLHLI 256
Cdd:PRK09802 253 SLEGLRKAGVEVILV 267
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 82-236 1.35e-61

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 191.19  E-value: 1.35e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   82 KQELGKVAASLVNDGDRLLLDSGTTTQQVAANLLEHQDLIVMTNGLNIATELARSDDVEVMLTGGLLRKKSMSFYGSIAE 161
Cdd:pfam00455   6 KRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFVGPLAE 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 655374811  162 KSLRDYNFNKLILGVDGFDLKTGLTTHFEKEASLNRMMCEIASEIIVVTDSSKFDQQAFHVICASRQIQQLVTDS 236
Cdd:pfam00455  86 EFLRQFNVDKAFIGANGIDLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITDK 160
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
9-59 2.51e-13

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 63.01  E-value: 2.51e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 655374811     9 RQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGA 59
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGA 51
 
Name Accession Description Interval E-value
AgaR NF040755
transcriptional repressor AgaR;
4-251 4.28e-119

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 340.40  E-value: 4.28e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   4 LNTIERQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGAMVNSDLIR--ELSLKEKGHCYSAL 81
Cdd:NF040755   2 KGTSERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALINDGFIPgaEPSVEDKSRLNTAV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811  82 KQELGKVAASLVNDGDRLLLDSGTTTQQVAANLLEHQDLIVMTNGLNIATELARSDDVEVMLTGGLLRKKSMSFYGSIAE 161
Cdd:NF040755  82 KRLIAAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVMTNGLNVANELLEAEGVEVLMTGGHLRRQSLSFYGDQAE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811 162 KSLRDYNFNKLILGVDGFDLKTGLTTHFEKEASLNRMMCEIASEIIVVTDSSKFDQQAFHVICASRQIQQLVTDSGIPER 241
Cdd:NF040755 162 QSLQNYHFDKLFLGVDGFDLERGITTHNEDEARLNRRMCEVAERIIAVTDSSKFGRSSLHKIRDTGRIDTLITDSGIPEE 241

                        250
                 ....*....|
gi 655374811 242 YVEELTKQGV 251
Cdd:NF040755 242 YLQGLRKLGV 251
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 5-257 1.55e-103

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 300.90  E-value: 1.55e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   5 NTIERQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGAMVNSDLIRELSLKEKGHCYSALKQE 84
Cdd:COG1349    2 LAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNAEEKRA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811  85 LGKVAASLVNDGDRLLLDSGTTTQQVAANLLEHQDLIVMTNGLNIATELARSDDVEVMLTGGLLRKKSMSFYGSIAEKSL 164
Cdd:COG1349   82 IARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEAL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811 165 RDYNFNKLILGVDGFDLKTGLTTHFEKEASLNRMMCEIASEIIVVTDSSKFDQQAFHVICASRQIQQLVTDSGIPERYVE 244
Cdd:COG1349  162 RRFRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPELLE 241

                        250
                 ....*....|...
gi 655374811 245 ELTKQGVQLHLID 257
Cdd:COG1349  242 ALEEAGVEVIVAE 254
PRK09802 PRK09802
DeoR family transcriptional regulator;
4-256 2.20e-86

DeoR family transcriptional regulator;


Pssm-ID: 182086 [Multi-domain]  Cd Length: 269  Bit Score: 258.25  E-value: 2.20e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   4 LNTIERQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGAMV--NSDLIRELSLKEKGHCYSAL 81
Cdd:PRK09802  13 TGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALIcdSTTPSVEPSVEDKSALNTAM 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811  82 KQELGKVAASLVNDGDRLLLDSGTTTQQVAANLLEHQDLIVMTNGLNIATELARSDDVEVMLTGGLLRKKSMSFYGSIAE 161
Cdd:PRK09802  93 KRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAE 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811 162 KSLRDYNFNKLILGVDGFDLKTGLTTHFEKEASLNRMMCEIASEIIVVTDSSKFDQQAFHVICASRQIQQLVTDSGIPER 241
Cdd:PRK09802 173 QSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPAD 252

                        250
                 ....*....|....*
gi 655374811 242 YVEELTKQGVQLHLI 256
Cdd:PRK09802 253 SLEGLRKAGVEVILV 267
srlR PRK10434
DNA-binding transcriptional repressor;
7-258 3.74e-73

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 223.80  E-value: 3.74e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   7 IERQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGAMVNSDLIrELSLKEKGHCYSALKQELG 86
Cdd:PRK10434   4 RQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEES-DPPIDHKTLINTHKKELIA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811  87 KVAASLVNDGDRLLLDSGTTTQQVAANLLEHQDLIVMTNGLNIATELARSD-DVEVMLTGGLLRKKSMSFYGSIAEKSLR 165
Cdd:PRK10434  83 EAAVSLIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSLHIVNALSELDnEQTILMPGGTFRKKSASFHGQLAENAFE 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811 166 DYNFNKLILGVDGFDLKTGLTThFEKEASLNRMMCEIASEIIVVTDSSKFDQQAFHVICASRQIQQLVTDSGIPERYVEE 245
Cdd:PRK10434 163 HFTFDKLFIGTDGIDLNAGVTT-FNEVYTVSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAGIDPAFRQA 241

                        250
                 ....*....|...
gi 655374811 246 LTKQGVQLHLIDK 258
Cdd:PRK10434 242 LEEKGIEVIITGE 254
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 82-236 1.35e-61

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 191.19  E-value: 1.35e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   82 KQELGKVAASLVNDGDRLLLDSGTTTQQVAANLLEHQDLIVMTNGLNIATELARSDDVEVMLTGGLLRKKSMSFYGSIAE 161
Cdd:pfam00455   6 KRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFVGPLAE 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 655374811  162 KSLRDYNFNKLILGVDGFDLKTGLTTHFEKEASLNRMMCEIASEIIVVTDSSKFDQQAFHVICASRQIQQLVTDS 236
Cdd:pfam00455  86 EFLRQFNVDKAFIGANGIDLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITDK 160
PRK10906 PRK10906
DeoR/GlpR family transcriptional regulator;
8-255 1.03e-31

DeoR/GlpR family transcriptional regulator;


Pssm-ID: 182827 [Multi-domain]  Cd Length: 252  Bit Score: 117.27  E-value: 1.03e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   8 ERQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGAMVNSDLIRElSLKEKGHCYSALKQELGK 87
Cdd:PRK10906   5 QRHDAIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNKILRHHGGAALPSSSVNT-PWHDRKATQTEEKERIAR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811  88 VAASLVNDGDRLLLDSGTTTQQVAANLLEHQDLIVMTNGLNIATELARSDDVEVMLTGGLLRKKSMSFYGSIAEKSLRDY 167
Cdd:PRK10906  84 KVASQIPNGATLFIDIGTTPEAVAHALLNHSNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATLDFISQF 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811 168 NFNKLILGVDGFDLKTGLTTHFEKEASLNRMMCEIASEIIVVTDSSKFDQQAFHVICASRQIQQLVTDSGIPERYVEELT 247
Cdd:PRK10906 164 RLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDQLPPASVMQVIE 243


                 ....*...
gi 655374811 248 KQGVQLHL 255
Cdd:PRK10906 244 DHHVQLEL 251
PRK13509 PRK13509
HTH-type transcriptional regulator UlaR;
4-256 1.11e-19

HTH-type transcriptional regulator UlaR;


Pssm-ID: 184100 [Multi-domain]  Cd Length: 251  Bit Score: 85.06  E-value: 1.11e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   4 LNTIERQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGA-MVNSDLIRELSLKEKGHCYSALK 82
Cdd:PRK13509   1 MTEAQRHQILLELLAQLGFVTVEKVIERLGISPATARRDINKLDESGKLKKVRNGAeAITQQRPRWTPMNIHQAQNHDEK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811  83 QELGKVAASLVNDGDRLLLDSGTTTQqVAANLLEHQDLIVMTNGLNIATELARSDDVEVMLTGGLLrKKSMSFYGSIAEK 162
Cdd:PRK13509  81 VRIAKAASQLCNPGESVVINCGSTAF-LLGRELCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQY-NKSQSITLSPQGS 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811 163 SLRDYNFNKLilgvdgFDLKTGLTTH-FEKEASLNRM----MCEIASEIIVVTDSSKFDQQAFHVICASRQIQQLVTDSG 237
Cdd:PRK13509 159 ENSLYAGHWM------FTSGKGLTADgLYKTDMLTAMaeqkMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKN 232

                        250
                 ....*....|....*....
gi 655374811 238 IPERYVEELTKQGVQLHLI 256
Cdd:PRK13509 233 ADPEVLQQLEAQGVSILLV 251
PRK10411 PRK10411
L-fucose operon activator;
8-235 7.57e-14

L-fucose operon activator;


Pssm-ID: 236684 [Multi-domain]  Cd Length: 240  Bit Score: 69.06  E-value: 7.57e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   8 ERQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGAMV----NSDLIRELSLKEKGHcySALKQ 83
Cdd:PRK10411   4 ARQQAIVDLLLNHTSLTTEALAEQLNVSKETIRRDLNELQTQGKILRNHGRAKYihrqNQDSGDPFHIRLKSH--YAHKA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811  84 ELGKVAASLVNDGDRLLLDSGTTTQQVAANLLEhQDLIVMTNGLNIATELARSDDVEVMLTGGLLRKKSMSFYGSIAEKS 163
Cdd:PRK10411  82 DIAREALAWIEEGMVIALDASSTCWYLARQLPD-INIQVFTNSHPICQELGKRERIQLISSGGTLERKYGCYVNPSLISQ 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 655374811 164 LRDYNFNKLILGVDGFDLKTGLTTHFEKEASLNRMMCEIASEIIVVTDSSKFDQQAFHVICASRQIQQLVTD 235
Cdd:PRK10411 161 LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISD 232
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
9-59 2.51e-13

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 63.01  E-value: 2.51e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 655374811     9 RQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGA 59
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGA 51
HTH_DeoR pfam08220
DeoR-like helix-turn-helix domain;
9-63 7.59e-13

DeoR-like helix-turn-helix domain;


Pssm-ID: 285436 [Multi-domain]  Cd Length: 57  Bit Score: 61.51  E-value: 7.59e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 655374811    9 RQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGGAMVNS 63
Cdd:pfam08220   1 RIQQILELLKQQGTLSVEELAELLGVSEMTIRRDLNELEEQGLLTRTHGGAVSNS 55
PRK10681 PRK10681
DNA-binding transcriptional repressor DeoR; Provisional
 9-253 2.60e-10

DNA-binding transcriptional repressor DeoR; Provisional


Pssm-ID: 182644 [Multi-domain]  Cd Length: 252  Bit Score: 58.94  E-value: 2.60e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811   9 RQQEIVRLTQ---QQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVrsrGGAMVN----------SD----LIRElsl 71
Cdd:PRK10681   5 RDERIGQLLQalkRSDKLHLKDAAALLGVSEMTIRRDLNAHSAPVVLL---GGYIVLeprsashyllSDqksrLVEE--- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811  72 kekghcysalKQELGKVAASLVNDGDRLLLDSGTTTQQVAANLLEHQDLIVMTNGLNIATELARSDDVEVMLTGGLLRKK 151
Cdd:PRK10681  79 ----------KRRAAQLAATLVEPNQTLFFDCGTTTPWIIEAIDNELPFTAVCYSLNTFLALQEKPHCRAILCGGEFHAS 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655374811 152 SMSFYGSIAEKSLRDYNFNKLILGVDGFDLKTGLTT-HFEKEASLNRMMcEIASEIIVVTDSSKFDQQAFHVICASRQIQ 230
Cdd:PRK10681 149 NAIFKPLDFQQTLDNICPDIAFYSAAGVHVSKGATCfNLEELPVKHWAM-AMAQKHVLVVDHSKFGKVRPARMGDLTRFD 227

                        250       260
                 ....*....|....*....|...
gi 655374811 231 QLVTDSGIPERYVEELTKQGVQL 253
Cdd:PRK10681 228 TVVSDRCPDDEFVKYAQAQRIKL 250
YobV COG2378
Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains ...
 5-46 3.31e-06

Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains [Transcription];


Pssm-ID: 441945 [Multi-domain]  Cd Length: 314  Bit Score: 47.38  E-value: 3.31e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 655374811   5 NTIERQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVL 46
Cdd:COG2378    2 SRLERLLALLQLLQSRRGVTAAELAERLEVSERTIYRDIDAL 43
HTH_11 pfam08279
HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.
 10-58 2.11e-04

HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.


Pssm-ID: 429896 [Multi-domain]  Cd Length: 52  Bit Score: 38.18  E-value: 2.11e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 655374811   10 QQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGG 58
Cdd:pfam08279   1 LQILQLLLEARGPISGQELAEKLGVSRRTIRRDIKILEELGVPIEAEPG 49
COG2345 COG2345
Predicted transcriptional regulator, ArsR family [Transcription];
8-59 2.55e-03

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441914 [Multi-domain]  Cd Length: 217  Bit Score: 37.98  E-value: 2.55e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 655374811   8 ERQQEIVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRS--RGGA 59
Cdd:COG2345   13 PTRRRILELLKRAGPVTAAELAEALGLTPNAVRRHLDALEEEGLVEREteRRGR 66
MngR COG2188
DNA-binding transcriptional regulator, GntR family [Transcription];
24-57 3.98e-03

DNA-binding transcriptional regulator, GntR family [Transcription];


Pssm-ID: 441791 [Multi-domain]  Cd Length: 238  Bit Score: 37.53  E-value: 3.98e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 655374811  24 SVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRG 57
Cdd:COG2188   31 SERELAEEFGVSRMTVRKALDELVEEGLLERRQG 64
HTH_PafC pfam19187
PafC helix-turn-helix domain; This entry is an N-terminal HTH domain found in the PafC protein. ...
 18-46 5.17e-03

PafC helix-turn-helix domain; This entry is an N-terminal HTH domain found in the PafC protein. Transcriptional activator PafBC is responsible for upregulating the majority of genes induced by DNA damage.


Pssm-ID: 465990 [Multi-domain]  Cd Length: 115  Bit Score: 36.00  E-value: 5.17e-03
                          10        20
                  ....*....|....*....|....*....
gi 655374811   18 QQQGKVSVTELANRFGVSEVTIRSDLAVL 46
Cdd:pfam19187  14 RQHPGVSVAEAAARFGVTPAQLRADLDVL 42
MntR COG1321
Mn-dependent transcriptional regulator MntR, DtxR family [Transcription];
13-58 7.62e-03

Mn-dependent transcriptional regulator MntR, DtxR family [Transcription];


Pssm-ID: 440932 [Multi-domain]  Cd Length: 135  Bit Score: 35.95  E-value: 7.62e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 655374811  13 IVRLTQQQGKVSVTELANRFGVSEVTIRSDLAVLDQKQLLVRSRGG 58
Cdd:COG1321   15 IYELSEEGGPVRTSDIAERLGVSPPSVTEMLKKLEEKGLVEYEPYG 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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