|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_like_2 |
cd13149 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
7-438 |
1.57e-133 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240554 [Multi-domain] Cd Length: 434 Bit Score: 391.67 E-value: 1.57e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 7 LLSQPIGRVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHA 86
Cdd:cd13149 2 LTEGSIPRHLIKLTLPMIFGILAMLIFNLTDTFFVGKLGTKELAAISFTFPVVLFLNSLTIGLGIGASAVISRAIGAGDR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 87 PKAKVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPA 166
Cdd:cd13149 82 NKAKRLATDSLILSLLLSVIVSLLGLFTIPPLFSLLGASGEILPLIVEYMAIWYLGLVFLVLPMVGNAIIRATGDTKRPS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 167 AILSLAALINLILDPLLIFGIGPFPRLEIQGAAVATLISWLVALSLSSYLLVVKRHMLVAAGWCFSRFADNWKQLAHIAQ 246
Cdd:cd13149 162 LVMLGAALVNVILDPILIFGFGPIPGMGIAGAAIATVISRALGLGAALYFLHYHHRLIDFSEPSLKALFRSWKDILSIGI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 247 PAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVL 326
Cdd:cd13149 242 PAALSNILTPLSAAFITALVATYGPAAVAAFGVATRIESFAFIIVMALSSALGPFVGQNWGAGQYERVQEGLKISLKFSL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 327 LFQTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLFLLMLPLA 406
Cdd:cd13149 322 IYGAILGIVLALFAGWLASLFSAEPEVIELITLYLLIVPIGYGGLGILIITSASFNALGKPLYSLGLNLIRVFLLYIPLA 401
|
410 420 430
....*....|....*....|....*....|..
gi 655375171 407 ALGAFLGGVKGLMLALPVTNILMGIASYYLAS 438
Cdd:cd13149 402 YVGSHLLGFAGVFIGALAGNLIAGILAYFIAK 433
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
7-436 |
2.92e-90 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 280.49 E-value: 2.92e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 7 LLSQPIGRVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHA 86
Cdd:COG0534 1 LTEGPILKLLLRLALPIILGNLLQSLYGLVDTIFVGRLGTAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGDR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 87 PKAKVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPA 166
Cdd:COG0534 81 EEARRVLGQALLLALLLGLLLTLLGLLFAPPLLRLLGADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 167 AILSLAALINLILDPLLIFGigpfPRLEIQGAAVATLISWLVALSLSSYLLVVKRHMLVAAGWCFSRFADNWKQLAHIAQ 246
Cdd:COG0534 161 IIMLIGNVLNIVLDPLLIFG----GGLGVAGAALATVISQAVSALLLLYYLFRKRSLLRLRLRDLRPDRKILKRILRIGL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 247 PAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVL 326
Cdd:COG0534 237 PAGLQQLAESLGFLVLNALVARLGTAAVAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGDYDRARRAARLALLLAL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 327 LFQTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLFLLMLPLA 406
Cdd:COG0534 317 GIGLLLALLLFLFPEPIIGLFTDDPEVIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLLRLWLVRLPLA 396
|
410 420 430
....*....|....*....|....*....|.
gi 655375171 407 ALGAFLG-GVKGLMLALPVTNILMGIASYYL 436
Cdd:COG0534 397 YLLAFLGlGLTGVWLALPIGEVLRALLLLLR 427
|
|
| MATE_like_4 |
cd13144 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
9-440 |
1.42e-77 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240549 [Multi-domain] Cd Length: 434 Bit Score: 247.92 E-value: 1.42e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 9 SQPIGRVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPK 88
Cdd:cd13144 3 SGPVLRLLLTMSIPAMISMLFQALYNIVDSIFVARLGENALTAVSLAFPIQNLMIAVAVGTGVGVNALLSRSLGEKDQKE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 89 AKVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAI 168
Cdd:cd13144 83 ANKAANNGLLLALLSYLLFLLLGLFGVKPFFRLFTDDPEILEYGYAYLSWCVIFSFGMFFQILCEKVLQSTGNTITPMIA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 169 LSLAALINLILDPLLIFGIGPFPRLEIQGAAVATLISWLVALSLSSYLLVVKRHMLVAAGWCFSRFADNWKQLAHIAQPA 248
Cdd:cd13144 163 QLIGAIINIILDPILIFGLFGFPAMGIAGAAIATVIGQILAMFLAFFFLLRKNKDVQPDLRLFRPSLRIIKEIYAVGLPS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 249 ALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLF 328
Cdd:cd13144 243 IIMQAISSVMVFGLNKILAGFGPTAVAVFGIYFKLQSFVFMPVFGLNNGLIPIVAYNYGAGNKDRIREAIKYAILIAVVI 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 329 QTLLYIPLALLAPQIAALFSTDPQVLEwLSFYVL-VLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLFLLMLPLAA 407
Cdd:cd13144 323 MLAGGLLFQLFPDQLLGLFNASEEMLA-IGVPALrIISLSFLFAALSIILSGLFQALGRGVYSLIISVARQLVVLLPLAW 401
|
410 420 430
....*....|....*....|....*....|...
gi 655375171 408 LGAFLGGVKGLMLALPVTNILMGIASYYLASNI 440
Cdd:cd13144 402 LLAKMFGLNGVWWSFPIAEIVSFLLSLLFLKRL 434
|
|
| MATE_like_12 |
cd13142 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
7-434 |
8.73e-75 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 240.94 E-value: 8.73e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 7 LLSQPIGRVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHA 86
Cdd:cd13142 4 ILEGSILRTLLKLAWPIIVSNLLQVAYNLADTFWLGRLGADAVAAPSISWPLIFLFISLGGGLTVAGTALVAQYTGAGDY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 87 PKAKVFLHDALLLTFILTAGLSLLGSLCIDPLF-SLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSP 165
Cdd:cd13142 84 DKANKVAGQTFSFVIILSLILAVLGYILSRPLLlLLIGAPEEVYPLALAYLRIIFLGLPFMFIFFVFNSLLRGIGDTKTP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 166 AAILSLAALINLILDPLLIFGIGPFPRLEIQGAAVATLISWLVALSLSSYLLVVKRHMLvAAGWCFSRFADNW-KQLAHI 244
Cdd:cd13142 164 MKIMFGSVLLNVILDPLLIFGIGPFPGLGVAGAALATVISRGIAAVIGLYLLFKGRVGL-KISLRDLKPDWEWlKKIFRI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 245 AQPAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKF 324
Cdd:cd13142 243 GLPSSIEQSARALGFTVMTALVAGFGTVVVAAYGIGNRIISLVFLPAFGLARATSTMVGQNLGAGQIDRAEEIVKKAALL 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 325 VLLFQTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLFLLMLP 404
Cdd:cd13142 323 IFLILVIGGVLAFLFAEPIVRVFINDPEVIKEGADFLRIVAPSFPFFGLFQVINGAFRGSGHTLTAMIISILRLWVIRIP 402
|
410 420 430
....*....|....*....|....*....|..
gi 655375171 405 LAALGAFLG--GVKGLMLALPVTNILMGIASY 434
Cdd:cd13142 403 LAYLLAYVLglGVTGIWIAMAISNIVAALIAL 434
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
14-435 |
8.05e-71 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 230.48 E-value: 8.05e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 14 RVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKAKVFL 93
Cdd:cd13137 1 RRIWSLAWPVILENLLQTLVGLVDVFMVGRLGAEAIAAVGLATQVLWLLLVLNMALGTGTVALVSQSYGAGDYERARRAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 94 HDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSLAA 173
Cdd:cd13137 81 GQSLLLALLLSLPLALLGLLFAEPLLRLLGADPEVIALALTYLRIVLLGIPFFFLSLVGNAALRGAGDTKTPMYIMIIVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 174 LINLILDPLLIFGIGPFPRLEIQGAAVATLISWLVALSLSSYLLVVKRHMLVAAGWCFSRFADNWKQLAHIAQPAALMNM 253
Cdd:cd13137 161 VLNIVLDYVLIFGLWGFPGLGVAGAALATVISRVVGALLLLFLLLRGRLPIKISFKGFRLDRKIIKKLLRIGLPAGLEQL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 254 INPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLFQTLLY 333
Cdd:cd13137 241 LRSLGFLVLLAIVASYGTAALAAYQIGLRIESLAFMPGFGFSMAASTLVGQNLGAGDPDEARRYGKRALRLGVLFMGLLG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 334 IPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLFLLMLPLAALGAFL- 412
Cdd:cd13137 321 LLLFIFAPPLASLFTPDPEVIELGVLYLRIVALSQPFLAISFVLSGALRGAGDTRPPLIINLISMWLVRLPLAYLLGFVl 400
|
410 420
....*....|....*....|....
gi 655375171 413 -GGVKGLMLALPVTNILMGIASYY 435
Cdd:cd13137 401 gLGLTGIWLAMFVDTIVRAILLLY 424
|
|
| MATE_like_5 |
cd13145 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
7-440 |
1.09e-67 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 222.47 E-value: 1.09e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 7 LLSQPIGRVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHA 86
Cdd:cd13145 2 LTKGPIPKLIRKLAIPASVGFFFNTMFNVVDTFFAGKISTEALAALSLSFPIFFIIIAIGVGIGTGTTALIGNALGAGDR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 87 PKAKVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPA 166
Cdd:cd13145 82 RKARRYAAQGLSFGIILAILLTVIGLFAAPPLFRLLGAEGDYLDLALEYMDVIFAGSIFFLLNFGLNGILNAQGDTKSYR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 167 AILSLAALINLILDPLLIFGIGPFPRLEIQGAAVATLISWLVALslsSYLLVVKRHMLVAAGWCFSRFA---DNWKQLAH 243
Cdd:cd13145 162 NFLIIGFFLNIILDPLFIFGGGGIPAMGVSGIALATIISQFIGM---FYLLYKVRKSGIISGCRLRDFIprlDVYKEILK 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 244 IAQPAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALK 323
Cdd:cd13145 239 QGFPASLNMMTIGLGIFVITYFVGQFGDEAVAAYGIALRIEQILLLPTIGLNTAVLSIAGQNFGAKKYDRVRETYKKALK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 324 FVLLFQTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLFLLML 403
Cdd:cd13145 319 YGFVIMVVATVFLLFFAEPLMSLFTNDPAVIAIGAGYLRIDALIFYAYVVLFISVSVLQGLKRPIFALWIGLYRQLVGPA 398
|
410 420 430
....*....|....*....|....*....|....*....
gi 655375171 404 PLAAL--GAFLGGVKGLMLALPVTNILMGIASYYLASNI 440
Cdd:cd13145 399 LVFWLlvNVLGLGVTGIWWGIFTIVWSAAIIALLYTRRV 437
|
|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
11-436 |
2.65e-67 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 221.23 E-value: 2.65e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 11 PIGRVLLNMSVPNMLGILTVLGFNLVDTYFISKL-GTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKA 89
Cdd:cd13143 1 PIGKLFLKFALPAIIGMLVNGLYNIVDGIFVGHGvGALALAAVNLVFPIIMLLMALGLMIGVGGASLISRRLGAGDREKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 90 KVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAIL 169
Cdd:cd13143 81 NRIFSTALLLSLILGLLLTILGLLFLDPLLRLLGASGELLPYAVDYLRIILLGAPFTILSSVLNNLLRAEGKPKLAMLGM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 170 SLAALINLILDPLLIFGIGpfprLEIQGAAVATLISWLVALSLSSYLLVVKRHMLVAAGWCFSRFADNWKQLAHIAQPAA 249
Cdd:cd13143 161 LIGAVLNIILDPLFIFVLG----LGIAGAALATVIAQLISLLLLLLYFFRGKSLLKLSLLRFKLSLKIIKEILALGFPSF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 250 LMNMINPLANAAIMGMLARIDH-AAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLF 328
Cdd:cd13143 237 LMQLSSSVVTIVLNLTLLGYGGdIGVAAFGIVTRILTFLFLPLIGLSQGLQPIIGYNYGAGNYDRVKQALKLALIVALIY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 329 QTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLFLLMLPLAAL 408
Cdd:cd13143 317 GLVLFLILLLFPEQIVSLFTDDPELIALAARILRIFLLAFPLAGINIVLSGYFQAIGKAKRAALLSLLRQGLFLIPLLLI 396
|
410 420
....*....|....*....|....*...
gi 655375171 409 GAFLGGVKGLMLALPVTNILMGIASYYL 436
Cdd:cd13143 397 LPRLFGLDGIWLAFPLAEILTLLLALIL 424
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
12-436 |
1.69e-64 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 213.86 E-value: 1.69e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 12 IGRVLLNMSVPNMLGILTVLGFNLVDTYFISK-LGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKAK 90
Cdd:cd13138 1 ILKTLLLFALPLLLSNLLQQLYNLVDLLIVGQfLGVAALAAVSNGSPIIFLLTAIGMGLSMGGTILISQYIGAKDEEKAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 91 VFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILS 170
Cdd:cd13138 81 KAVGTLLVLFLILGIVLTILGLLFAPPILRLMNTPAEILELAVSYLRICFLGIPFIFGYNAYSAILRGLGDSKTPLYFVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 171 LAALINLILDPLLIFGigpfPRLEIQGAAVATLISWLVALSLSSYLLVVKRHMLVAAGWCFSRFADNWKQLAHIAQPAAL 250
Cdd:cd13138 161 IACVLNIILDLLFIAV----FHMGVAGAALATVIAQAISVLLALYYLRKKKLPFKLSLKDFRFDKEILKEILKIGLPSAL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 251 MNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLFQT 330
Cdd:cd13138 237 QQSLVSISFLIINSIVNSYGVVASAAYGIANKINSFAFLPPSAIGQAVSTFVAQNIGAGKIERAKKGLRTGIIISLIIGL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 331 LLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLFLLMLPLA-ALG 409
Cdd:cd13138 317 IIILLVFFFAPQLLGLFTSDPEVIEIGAEYLRIYSIDYILFGILFVFNGLFRGLGKTKFPMIISILRLWLVRIPLAyLLS 396
|
410 420
....*....|....*....|....*...
gi 655375171 410 AFLG-GVKGLMLALPVTNILMGIASYYL 436
Cdd:cd13138 397 RLTGlGLFGIWLAMPISNILSAIICIIY 424
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
20-436 |
4.69e-54 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 185.99 E-value: 4.69e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 20 SVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKAKVFLHDALLL 99
Cdd:cd12082 1 AAPLLLSMLLQTLYNLVDTFFLGRLLGDALAAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 100 TFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSLAALINLIL 179
Cdd:cd12082 81 AILLGLLLAALLLFFSPLILSLLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSNLLNILL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 180 DPLLIFGIGPfPRLEIQGAAVATLISWLVALSLSSYLLVVKRHMLVAAGWCFSRFADNWKQLAHIAQPAALMNMINPLAN 259
Cdd:cd12082 161 DPLLIFGLGP-PELGIAGAALATVISYVIGALLLLIYLRKGKKILKFKLSLLKPDLELLRRLLRIGLPSAIQNSLLSLGL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 260 AAIMGMLARI-DHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLFQTLLYIPLAL 338
Cdd:cd12082 240 LIIVAIVAAFgGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIGAVLGLLILL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 339 LAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLFLLMLPLAALGAFLG-GVKG 417
Cdd:cd12082 320 FPEPILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSLLSYWVVRLPLAYVLAYLGlGLYG 399
|
410
....*....|....*....
gi 655375171 418 LMLALPVTNILMGIASYYL 436
Cdd:cd12082 400 IWLALVISLILAALVLLLF 418
|
|
| MATE_like_14 |
cd13139 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
9-436 |
1.04e-44 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240544 [Multi-domain] Cd Length: 448 Bit Score: 161.63 E-value: 1.04e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 9 SQPIGRVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPK 88
Cdd:cd13139 9 SGSLNRAIFLLAIPMVLEMVMESLFAVVDLYFVSRLGALAIATVGLTESVLTIVYSIAIGLSMAATALVARRIGEKDPEG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 89 AKVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAI 168
Cdd:cd13139 89 AGFAAVQAILLGVALSLILSILGYFFAEDILSLMGASPAVIAEGYGYTRIMFGGNGFIMLLFLINGIFRGAGDAAIAMRS 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 169 LSLAALINLILDPLLIFGIGPFPRLEIQGAAVATLISWLVALSLSSYLLVVKRHMLVAAGWCFSRFADNWKQLAHIAQPA 248
Cdd:cd13139 169 LWLANGLNIILDPLFIFGLGPIPAMGVTGAAIATTIGRSIGVLYQLYHLFKGKGRIQIRRRHLKLDWAIIKKIIKIAVGG 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 249 ALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLF 328
Cdd:cd13139 249 ILQFLIASSSWIFLVRIIAEFGSTALAGYTIAIRIIMFALLPAWGLSNAAATLVGQNLGAGQPDRAEKSVWRAGKYNMVF 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 329 QTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLFLLMLPLAAL 408
Cdd:cd13139 329 LGIVSLVFFLFAEPLVSFFTTDPEVIAIAVEALRIISLGYIFYGYGMVLSQAFNGAGDTKTPTLINLVGFWLFQIPLAYL 408
|
410 420 430
....*....|....*....|....*....|
gi 655375171 409 GA--FLGGVKGLMLALPVTNILMGIASYYL 436
Cdd:cd13139 409 LArhLNLGPKGVFIAIPIAETVLAIAAIIL 438
|
|
| MATE_MJ0709_like |
cd13147 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, ... |
16-434 |
3.96e-44 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, similar to Methanocaldococcus jannaschii MJ0709; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240552 [Multi-domain] Cd Length: 441 Bit Score: 160.01 E-value: 3.96e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 16 LLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKAKVFLHD 95
Cdd:cd13147 11 IIKLSIPMIIAMLLQTLYNLVDAIWVAGLGADALAAIGFVFPLFMIIIGLGNGLGAGASSAISRRIGAKDKEGADNAAVH 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 96 ALLLTFILTAGLSLLGSLCIDPLFSLLGAKdDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSLAALI 175
Cdd:cd13147 91 SILLGLIISIILTIVLLPFLEPILVLMGAG-EVLDLAVDYGRIIFLGSIFLIFNNVAYGILRGEGDTKRAMYAMVAGSIL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 176 NLILDPLLIFGIGpfprLEIQGAAVATLISWLVALSLSSYLLVVKRHMLVAAGWCFSRFadNWKQLAHI---AQPAALMN 252
Cdd:cd13147 170 NIILDPIFIYTLG----LGIAGAAWATVISMLISSLVLLYWFFVKKDTYVSLSLKNFKF--DKKIVKDIlkvGIPASLEQ 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 253 MINPLANAAIMGMLARI-DHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLFQTL 331
Cdd:cd13147 244 LIMSVLMIILNLILVIVaGTDGVAVYTAGWRIVSFAIIPLIGIATAVTSVTGAAYGARNYEKLKTAYNYSIKLGLIIELI 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 332 LYIPLALLAPQIAALFSTD-------PQVLEWLSFYVLVLPAAygPLGvviIVATSL-NAYHRPMASLVLNLCRLFLLML 403
Cdd:cd13147 324 IAILIFIFAPQIAYLFTYSeesahlaPEIVAFLRIMCLFLPFV--PFG---MMSSSMfQGIGKGLTSLIITILRELIFQV 398
|
410 420 430
....*....|....*....|....*....|...
gi 655375171 404 PLAALGAF-LG-GVKGLMLALPVTNILMGIASY 434
Cdd:cd13147 399 LFAYLFAIvLGlGLFGVWWGIVLGNAIGSIVGY 431
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
22-364 |
9.47e-44 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 156.64 E-value: 9.47e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 22 PNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKAKVFLHDALLLTF 101
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHLGPVDLAAVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLLLAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 102 ILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSLAALINLILDP 181
Cdd:TIGR00797 81 LLGLPVLLVGYFFIDPLLSLMGADGEVAELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINIILNY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 182 LLIFGIgpFPRLEIQGAAVATLIS-WLVALSLSSYLLVVKRHMLVAAGWCFSRFADNWKQLAhIAQPAALMNMINPLANA 260
Cdd:TIGR00797 161 ILIFGK--FGFLGIVGAALATVISyWLMFLLLLYYIKKAKKIGLKWEGLLKPDWEVLKRLLK-LGLPIAFRVILESLSFA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 261 AIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLFQTLLYIPLALLA 340
Cdd:TIGR00797 238 LLALLVARLGSIALAAHQIALNVESLLFMPAFGFGIAVSILVGQALGAGDPKRAKEVARVALKLSLLLGLVLAIILILFR 317
|
330 340
....*....|....*....|....
gi 655375171 341 PQIAALFSTDPQVLEWLSFYVLVL 364
Cdd:TIGR00797 318 EFIARLFTNDPEVLELAAIYLIFV 341
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
11-436 |
3.48e-43 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 157.30 E-value: 3.48e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 11 PIGRVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAIS----FTFPVTLVVSSIAIGIGAGVSTNlgrlIGAGHA 86
Cdd:cd13140 2 PILKTLLRLALPIMGTSFIQMAYNLTDMFWVGRLGSDAVAAVGtagfFVWLAYALALLSKIGAQVKVSQS----IGAKDE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 87 PKAKVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDD-ILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSP 165
Cdd:cd13140 78 KEARKYARNALQLNLLLGILYGLLLLLFAKPLIGFFNLGDAeVISLAITYLRIVALGLIFSFLNPVFTGIFNALGDSKTP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 166 AAILSLAALINLILDPLLIFGIGPFPRLEIQGAAVATLISWLVALSLssYLLVVKRHMLVAAGWCFSRFADN--WKQLAH 243
Cdd:cd13140 158 FIINAIGLVLNIILDPLLIFGFGPFPALGVAGAALATVLAQAIVFLL--FLYALKKKKGLFLKIRILKRPDRkyIKEILK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 244 IAQPAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERARE---ALLL 320
Cdd:cd13140 236 LGLPVALQSILFALISMILARIIASFGPVAIAAQKVGSQIESISWMTAEGFSTALAAFVGQNYGAGKYDRIRKgykTALK 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 321 ALKFVLLFQTLLYIplaLLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMA----SLVLNLC 396
Cdd:cd13140 316 IASAIGLFATLLLF---FFGEPLFSLFIPDPETIAIGVDYLRILGFSQLFMCLEITTTGAFNGLGRTKPpaiiSIVFNGL 392
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 655375171 397 RLFLLMLplaaLGAFLGGVKGLMLALPVTNILMGIASYYL 436
Cdd:cd13140 393 RIPLALL----LSPTGLGLNGIWWAISISSILKGIILTIW 428
|
|
| MATE_like_3 |
cd13148 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
4-431 |
3.31e-40 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240553 [Multi-domain] Cd Length: 441 Bit Score: 149.34 E-value: 3.31e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 4 RHGLLSQPIGRVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIG-IGAGVSTNLGRLIG 82
Cdd:cd13148 2 TRALLTAPILPTLLRLALPNILALLVQTLVGLAETYFVGQLGTDALAGVALVFPLLMLTQMMSNGaMGGGVSSAIARALG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 83 AGHAPKAKVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDT 162
Cdd:cd13148 82 AGDRERAEALVWHALVIALAGGLVFSLLFLLFGPALYRLLGGRGEALDAALAYSNVLFSGAILIWLVNLLAAALRGTGNM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 163 RSPAAILSLAALINLILDPLLIFGIGPFPRLEIQGAAVATLISW-LVALSLSSYLLV---VKRHMLVAAGWCFSRFADNW 238
Cdd:cd13148 162 RVPALVTLVGAVVQIPLSPGLILGWGPLPRLGVAGAAVAAVLYYaLAALVLLRYLASgrsRLRLRLRALRLERRLFRDIL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 239 KqlahIAQPAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREAL 318
Cdd:cd13148 242 R----VGLLAALSPLQTNLTVLLLTGLVGRFGTAALAGYGIGSRLEFLLIPLVFGLGAAMTAMVGMNIGAGQIARARRIA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 319 LLALKFVLLFQTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRL 398
Cdd:cd13148 318 WTGALMAAVLAGAIGLVLALFPELWLGLFTHDPAVLAAGASYLRIVGPFYGFFGLGLALYFASQGAGRMLWPVLAGTLRL 397
|
410 420 430
....*....|....*....|....*....|....
gi 655375171 399 FL-LMLPLAALGAFLGGVKGLMLALPVTNILMGI 431
Cdd:cd13148 398 LIaAGGGWIAVALFGAGLAGLFAAAAAAMVAYGL 431
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
14-435 |
1.79e-36 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 139.20 E-value: 1.79e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 14 RVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKAKVFL 93
Cdd:cd13133 5 REILKIALPLVLSMLSQTVMGFTDRAFLGRLSEVALAASGPAGVLYFAILMLFFGLSSGVQVFVAQYNGAGRYSRIGRVL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 94 HDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVlmvgNQGLRA----TGDTRSPAAIL 169
Cdd:cd13133 85 WQGLYFSLLLAPLLALLSALAAPLLFLLLGHSPEVQALEVEYFRIRILGAPFSLL----GAALRAffsgIGRTRVVMVAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 170 SLAALINLILDPLLIFGIGPFPRLEIQGAAVATLISWLVALSLSSYLLVVKRHM---LVAAGWCFSRfaDNWKQLAHIAQ 246
Cdd:cd13133 161 LVMVVVNIVLDYALIFGKLGFPAMGIAGAAIATVIAEAVSLLFFLLLLFRRKNRrrfGLRRAWRFDR--ELLRRILRLGL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 247 PAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVL 326
Cdd:cd13133 239 PSGLQFFLDVGAFTVFFLLIGRLGTTELAATNIVFSINSLAFLPMIGLGIAVSSLVGQALGAGRPDLAMRVTRRGLKLAL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 327 LFQTLLYIPLALLAPQIAALFST--DPQVLEWLSFYVLVLPAAYGPLGVVIIV-ATSLNAYHRPMASLVLNLCRLFLLML 403
Cdd:cd13133 319 AYMLLLGILFLLFPELLLSIFTPgaDFALIAELAVPLLRFVAAYILFDALALVfAGALRGAGDTRFVMLAELIVAWLYLL 398
|
410 420 430
....*....|....*....|....*....|...
gi 655375171 404 PLAALGAFLG-GVKGLMLALPVTNILMGIASYY 435
Cdd:cd13133 399 PPAYLLVVLGaGLAGAWTVETVYVIVLALIFLL 431
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
16-435 |
1.79e-35 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 136.48 E-value: 1.79e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 16 LLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKAKVFLHD 95
Cdd:cd13134 5 LFALAWPIFIELLLQMLLGTIDTFMLSRYSDNAVAAVGVANQILFLLILIFSFISTGTSILIAQYLGAKDKKKARQIAGV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 96 ALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSLAALI 175
Cdd:cd13134 85 ALLFNLLLGLVFSLLLLFFGAELLRLMGLPPELLALGSTYLRIVGGSLFLQALSLTLSAILRSHGRTKIPMYVSLIMNIL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 176 NLILDPLLIFGIGPFPRLEIQGAAVATLISWLVALSLSSYLLVVKRHMLVAAGWCFSRFADNWKQLAHIAQPAALMNMIN 255
Cdd:cd13134 165 NIVGNYLLIFGWFGLPKLGVAGVAISTVISRAVGLVLLFILLFRKLKIRFRLKDLRPFPKKLLKKILKIGLPSAGEELSY 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 256 PLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLFQTLLYIP 335
Cdd:cd13134 245 NLSQTVITAFIARLGTAALAARTYASNISMFVFLFSLAIGQATQIIVGHLVGAGDFDEAYKRVLKSLKIGLLVSLAVALL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 336 LALLAPQIAALFSTDPQVLEWLSfYVLVLPAAYGPLGVV-IIVATSLNAYHRPMASLVLNLCRLFLLMLPLAALGAFLG- 413
Cdd:cd13134 325 LALFREPILGLFTDDPEIIALGK-TLLLISILLEPGRAFnIVLIGSLRAAGDARFPVLIGIISMWGISVPLAYLLGIVLg 403
|
410 420
....*....|....*....|...
gi 655375171 414 -GVKGLMLALPVTNILMGIASYY 435
Cdd:cd13134 404 lGLLGVWIAFAADEWVRGIIMLW 426
|
|
| MATE_like_6 |
cd13146 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
7-436 |
4.70e-35 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240551 [Multi-domain] Cd Length: 433 Bit Score: 135.22 E-value: 4.70e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 7 LLSQPIGRVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEA---LAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGA 83
Cdd:cd13146 1 MFSGPISPLLIRLALPILIGQLFQLLYNITDTIWISMIDPSDpalVGGIGLVFPLGMIFLALGNGIQVGVSSLLARAIGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 84 GHAPKAKVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTR 163
Cdd:cd13146 81 QRAKELDQAADSGLALALLAATVIVVLGYIFAEPLLQLLGAKGLLLEYALEYFYYSLPGVPFIMLIGVLMGVLQGEGRTK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 164 SPAAILSLAALINLILDPLLIFGIgpfpRLEIQGAAVATLISWLVALSLSSYLLVVkRHMLVAAGWCFSRFADN-WKQLA 242
Cdd:cd13146 161 YMMMAMLIGTVVNIVLDPILIFVF----DMGVKGAALATVLAQAISLLYLLYVFLI-GKSNVTIHIKLSNISSSvIVEIL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 243 HIAQPAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLAL 322
Cdd:cd13146 236 RVGLPQMLLQLISSISFLIYNRIIIDIDPVAMTAFTLVGRLDQFILIPIFAISSALLTIAGQNWGRGNYDRMLQILMTAV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 323 KFVLLFQTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLFLLM 402
Cdd:cd13146 316 ILGIVVVLVLVLGYVLVAPWLFSLFTTVPEVVAYAVLQVRTMALALPFVAISILVTEFFQAIGKAWPSLLLTLIRHVFLS 395
|
410 420 430
....*....|....*....|....*....|....*.
gi 655375171 403 LPLAALGAFL--GGVKGLMLALPVTNILMGIASYYL 436
Cdd:cd13146 396 VPVVYLLAYVfgKGITGVYFGIVSANFFTALLAMFW 431
|
|
| MATE_like_13 |
cd13141 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
5-439 |
6.02e-34 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240546 [Multi-domain] Cd Length: 443 Bit Score: 132.05 E-value: 6.02e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 5 HGLLSQPIGRVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAG 84
Cdd:cd13141 2 KDLTQGSIPKHIISMALPIAIGMIIQTLYFLVDLYFVGQLGDAALAGVSLAGNVMFFVMALTQVLNVGTAALVSHAVGRK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 85 HAPKAKVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRS 164
Cdd:cd13141 82 DQGEANAVFNQSLLLAAVLGLVVLVLGYLFGRLYLETLAADAATVEAATTYLYWFIPSLALQFILTVLGAALRGTGIVKP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 165 PAAILSLAALINLILDPLLIFGIGPFPRLEIQGAAVATLISWLVALSLSSYLLVVKRHMLVAAGWCFSRFADNWKQLAHI 244
Cdd:cd13141 162 FMVIQILAVLLNIILAPILITGWGTGRALGVAGAGLASSISVAIAVVLLLYYFLRLEKYLRLDLALWRPDLPTWKRLLKI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 245 AQPAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKF 324
Cdd:cd13141 242 GLPSGGEFLLTFVYMAVIYWALRPFGAAAQAGFGIGSRIMQSLFLPAMAIAFAAPAIAGQNFGAGNYDRVRETFRITAIL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 325 VLLFQTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLFLLMLP 404
Cdd:cd13141 322 TTALMLVLTLLCQLVPELLVTPFSDDAAVIAVAATFLRYVSWNFVAAGLVFTCSGMFQALGNTWPSLLSSASRLLTFALP 401
|
410 420 430
....*....|....*....|....*....|....*.
gi 655375171 405 LAALGAFLGGVKGLMLALPV-TNILMGIASYYLASN 439
Cdd:cd13141 402 VIWLSAQPDFRIEQIWYLSVaTTILQAALSLLLLRR 437
|
|
| MATE_NorM_like |
cd13131 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio ... |
14-437 |
1.38e-29 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.
Pssm-ID: 240536 [Multi-domain] Cd Length: 435 Bit Score: 119.91 E-value: 1.38e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 14 RVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKAKVFL 93
Cdd:cd13131 3 RALLRLALPILIAQLAQMAMGFVDTVMAGRLGADDLAAVALGSSLWFPVFTFGMGLLLAVTPLVAQAHGAGDRRRIRRAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 94 HDALLLTFILTAGLSLLGSLcIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSLAA 173
Cdd:cd13131 83 RQGLWLALLLSLPLMLLLWL-APPILPLMGQEPEVAAIARGYLLALAWGIPPALLFQVLRSFLDALGRTRPAMVITLLAL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 174 LINLILDPLLIFGIGPFPRLEIQGAAVATLIS-WLVALSLssyLLVVKRHMLVAAGWCFSRFA----DNWKQLAHIAQPA 248
Cdd:cd13131 162 VLNIPLNYVLIFGKFGLPALGGAGAGLATAIVyWLMFLAL---AFYIRRHKRFRRYRLFARFWrpdwARLKELLRLGLPI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 249 ALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLF 328
Cdd:cd13131 239 GLTIFFEVSLFAAVALLMGRLGTTVLAAHQIALNFASLLFMVPLGISMAATVRVGFALGAGDPADARRAGLVGLGLGVGF 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 329 QTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVlpAAYGPL--GVVIIVATSLNAYHRPMASLVLNLCRLFLLMLPLA 406
Cdd:cd13131 319 AALTALLLLLFPEQIAGLYTNDPAVIALAASLLVF--AALFQLfdGIQVVAAGALRGYKDTRVPFLLALISYWGIGLPLG 396
|
410 420 430
....*....|....*....|....*....|....*..
gi 655375171 407 ALGAF---LGGVK---GLMLALPVTNILMGIASYYLA 437
Cdd:cd13131 397 YLLAFttgLGAFGvwiGLIIGLALAAILLLWRFRRLQ 433
|
|
| MATE_eukaryotic |
cd13132 |
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral ... |
14-436 |
2.72e-25 |
|
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. This subfamily, which is restricted to eukaryotes, contains vertebrate solute transporters responsible for secretion of cationic drugs across the brush border membranes, yeast proteins located in the vacuole membrane, and plant proteins involved in disease resistance and iron homeostatis under osmotic stress.
Pssm-ID: 240537 [Multi-domain] Cd Length: 436 Bit Score: 107.27 E-value: 2.72e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 14 RVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVS-SIAIGIGAGVSTNLGRLIGAGHAPKAKVF 92
Cdd:cd13132 3 KKLLRLAAPLVLTSLLQYSLSVVSVVFVGHLGKLELAAASLASSFANVTGfSILLGLASALDTLCGQAFGAKNYKLVGVY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 93 LHDALLLTFILTAGLSLLGsLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSLA 172
Cdd:cd13132 83 LQRALVILLLCCVPISLLW-LNTEPILLLLGQDPEIARLAGEYLRWLIPGLFAYALFEPLKRYLQAQGIVLPLVYISLVA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 173 ALINLILDPLLIFGIGpfprLEIQGAAVATLIS-WLVALSLSSYLLVVKRHMLVAAGWCFSRFADnWKQLAHIAQPAALM 251
Cdd:cd13132 162 LLLNILLNYLLVFVLG----LGFIGAALATSISyWLIVVLLLLYIFFSKGHKATWGGFSREAFRG-WGPFLKLAIPSALM 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 252 NMINPLANAAIM---GMLAriDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLF 328
Cdd:cd13132 237 LCLEWWAFEILVllaGLLP--GTVALAAQSICLTTTSLLYMIPLGISIAASVRVGNELGAGNPKRAKLAAIVALILSLVI 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 329 QTLLYIPLALLAPQIAALFSTDPQVLEW---LSFYVLVLPAAYGPLGVV--IIVATSlnayhRPMASLVLNLCRLFLLML 403
Cdd:cd13132 315 GVVVAILLLVLRDVWAYLFTSDEEVIALvadLLPILALFQIFDGLQAVLsgVLRGCG-----RQKLGAYVNLVAYYLIGL 389
|
410 420 430
....*....|....*....|....*....|....*
gi 655375171 404 PLAALGAFL--GGVKGLMLALPVTNILMGIASYYL 436
Cdd:cd13132 390 PVGLLLAFVlgLGLKGLWIGLIAGLILQAVILLLI 424
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
16-384 |
1.39e-21 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 96.59 E-value: 1.39e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 16 LLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAI----SFTFPVTLVVSSIAIGIGAGVStnlgRLIGAGHAPKAKV 91
Cdd:cd13135 3 INHIAIPLILQNLVSQLQMLVDRAFLGRISIRYYSAVgnvtTPFNTITGFLGSISIGFTILGS----QSVGAKDIKRIND 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 92 FLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSL 171
Cdd:cd13135 79 YAISSIVYNSIIGVILFLLWLFGARIIFVLFGVDGQILGYSINYVRIFSIYLLLLGILFTFSSILQGIGETKPIMYGGII 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 172 AALINLILDPLLIFGIGPFPRLEIQGAAVATLISWLVALSLSSYLLVVKRHML--VAAGWCFSRFADNWKQLAHIAQPAA 249
Cdd:cd13135 159 KNLLNVILDYVLIFGNFGFPRLGIIGAAIATTIANVLNLIILVYLCRKIKKLTfkLSNTKVLKANIRPYKFTIKLGLPLG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 250 LMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLFQ 329
Cdd:cd13135 239 GEEFLWNIGNLAVIRILNRIGELALGIYTLVFGIENIVLMPMYGYSSAALTLVGESIGKKDLKEALRIGNICLGLGLLIY 318
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 655375171 330 TLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAY 384
Cdd:cd13135 319 IAAAIVFLAFPYKILSLFTNDPELINYSIPYLIFIIIILFFKSINIVYGFAIRAI 373
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
22-182 |
1.55e-21 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 90.70 E-value: 1.55e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 22 PNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKAKVFLHDALLLTF 101
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 102 ILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSLAALINLILDP 181
Cdd:pfam01554 81 LLSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNIPLNY 160
|
.
gi 655375171 182 L 182
Cdd:pfam01554 161 L 161
|
|
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
16-374 |
9.41e-19 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 88.00 E-value: 9.41e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 16 LLNMSVPNMLGILTVLGFNLVDTYFISKLGTE------ALAAISFTFpVTLVVSSIAIGIGAGVSTNLGrligAGHAPKA 89
Cdd:cd13136 5 ILALALPAILSNITVPLLGLVDTAVVGHLGSAaylgavALGTTIFNT-LFWLFGFLRMGTTGLVAQALG----AGDREEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 90 KVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAIL 169
Cdd:cd13136 80 IALLVRALLLALAIGLLLILLQSPLLALALLLLGASAAVAALARQYLRIRILGAPAVLLNYVATGWFRGLQDTRTPLILQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 170 SLAALINLILDPLLIFGIGpfprLEIQGAAVATLISWLVALSLSSYLLVVKRHMLVAAGWCFSRFADNWKQLAHIAQPAA 249
Cdd:cd13136 160 IVGNVVNIVLDPLFVFGLG----WGVAGAALATVIAQYLGALLGLWLLRRRVRLLGKSLSRRLPSKAALKRLFKLNRDIF 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 250 LMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLFQ 329
Cdd:cd13136 236 IRTLALLAAFLFFTALAARLGDVILAANQILLQFWLLSSYFLDGFAYAAEALVGRALGAGDRKAARRVARRLLQWGLGLG 315
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 655375171 330 TLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLpAAYGPLGVV 374
Cdd:cd13136 316 VLLALLFFLGGEPIIRLFTDDPAVLALAATYLPWL-ALLPPIGAL 359
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
247-408 |
4.34e-13 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 66.82 E-value: 4.34e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 247 PAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVL 326
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 327 LFQTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRlFLLMLPLA 406
Cdd:pfam01554 81 LLSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIIS-LLLNIPLN 159
|
..
gi 655375171 407 AL 408
Cdd:pfam01554 160 YL 161
|
|
| PRK01766 |
PRK01766 |
multidrug efflux protein; Reviewed |
14-368 |
1.14e-12 |
|
multidrug efflux protein; Reviewed
Pssm-ID: 234981 [Multi-domain] Cd Length: 456 Bit Score: 69.46 E-value: 1.14e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 14 RVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAI----SFTFPVTLVVSSIAIGIGAGVStnlgRLIGAGHAPKA 89
Cdd:PRK01766 12 RQLLALALPILLAQVAQTAMGFVDTVMAGGVSATDLAAVaigtSIWLPVILFGHGLLLALTPIVA----QLNGAGRRERI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 90 KVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVgnqgLR----ATGDTRsP 165
Cdd:PRK01766 88 AHQVRQGLWLALFLSVLIMLVLYNAVPPILNMMNLEPEVADIAVGYLHALLWGIPAYLLYQV----LRsfidGLGKTK-P 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 166 AAILSLAAL-INLILDPLLIFGIGPFPRLEIQGAAVATLIS-WLVALSLSSYLLVVK--RHMLVAAGWCFSRFAdNWKQL 241
Cdd:PRK01766 163 TMVIGFLGLlINIPLNYIFIYGKFGFPELGGVGCGVATAIVyWVMFLAMLIYIKRARrfRDFRLFKGLYKPDWA-VIKRL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 242 AHIAQPAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLA 321
Cdd:PRK01766 242 LKLGLPIGLAIFFEVSLFAVVTLLVSPLGTVTVAAHQIALNFSSLLFMLPLSLAMALTIRVGFELGAGRTLDARQYAYIG 321
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 655375171 322 LKFVLLFQTLLYIPLALLAPQIAALFSTDPQVLEWLSfYVLVLPAAY 368
Cdd:PRK01766 322 LAVGLGMALLTAIFLVLFREQIALLYTDDPEVVALAS-HLLLFAALF 367
|
|
| vmrA |
PRK09575 |
MATE family efflux transporter; |
33-431 |
5.13e-09 |
|
MATE family efflux transporter;
Pssm-ID: 236576 [Multi-domain] Cd Length: 453 Bit Score: 58.08 E-value: 5.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 33 FNLVDTYFISK-LGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKAKVFLHDALLLTFILTAGLSLLG 111
Cdd:PRK09575 31 YQIVDGIFIGHyVGAEGLAGINMAWPVIGIILGIGLMVGMGTGSLLSIKRGEGDLEKAKRILTTGLLLLLLLGPIVSVIL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 112 SLCIDPLFSLLGAKDDILPLVHEYMNLWYLGApLLVVLMVGNQGLRATGDTRSPAAIL-SLAALINLILDPLLIFGIGpf 190
Cdd:PRK09575 111 FLFADDFLRAQGAEGRTLELALQYIQVLIWGC-LFTLGAIALPFLLRNDESPNLATGLmVIGALINIVLDYLFIGWLD-- 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 191 prLEIQGAAVATLISWLVALSLS-SYLLVVKRHMlvaaGWCFSRFADNWK---QLAHIAQPAALM----NMINPLANAAI 262
Cdd:PRK09575 188 --WGLTGAAIATALAQLVVTVLGlGYFFSSRANI----RLTLKELRFNWSlapKIVLLGSSSFFMylygSFVVALHNRLF 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 263 MGMLARIdhaAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLFQTLLYIPLALLAPQ 342
Cdd:PRK09575 262 MEYGSAL---TVGAYAIVGYLMVLYYLVAEGIAEGMQPPVSYYFGARQYDNIKKLLKLAMKVTVLAGIAWVLLLNLFPET 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 343 IAALF-STDPQVLEW------LSFYVLVLPaayGPLGVVIIVATSLNAYHRPMASLVLNLcrlfLLMLP-LAALGAFLgG 414
Cdd:PRK09575 339 MIALFnSGDSELIAEtivgirLHLFAMFLD---GFLVLASAYFMAVNQGGKALFISIGNM----LIQLPfLFILPKWL-G 410
|
410
....*....|....*..
gi 655375171 415 VKGLMLALPVTNILMGI 431
Cdd:PRK09575 411 VDGVWLAMPLSNIALSL 427
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
12-208 |
1.46e-08 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 56.75 E-value: 1.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 12 IGRVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKAKV 91
Cdd:cd13137 224 IIKKLLRIGLPAGLEQLLRSLGFLVLLAIVASYGTAALAAYQIGLRIESLAFMPGFGFSMAASTLVGQNLGAGDPDEARR 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 92 FLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSL 171
Cdd:cd13137 304 YGKRALRLGVLFMGLLGLLLFIFAPPLASLFTPDPEVIELGVLYLRIVALSQPFLAISFVLSGALRGAGDTRPPLIINLI 383
|
170 180 190
....*....|....*....|....*....|....*..
gi 655375171 172 AALINLIldpLLIFGIGPFPRLEIQGAAVATLISWLV 208
Cdd:cd13137 384 SMWLVRL---PLAYLLGFVLGLGLTGIWLAMFVDTIV 417
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
239-395 |
3.44e-08 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 55.59 E-value: 3.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 239 KQLAHIAQPAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREAL 318
Cdd:cd13134 3 LSLFALAWPIFIELLLQMLLGTIDTFMLSRYSDNAVAAVGVANQILFLLILIFSFISTGTSILIAQYLGAKDKKKARQIA 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 655375171 319 LLALKFVLLFQTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNL 395
Cdd:cd13134 83 GVALLFNLLLGLVFSLLLLFFGAELLRLMGLPPELLALGSTYLRIVGGSLFLQALSLTLSAILRSHGRTKIPMYVSL 159
|
|
| PRK10189 |
PRK10189 |
EmmdR/YeeO family multidrug/toxin efflux MATE transporter; |
19-205 |
1.51e-07 |
|
EmmdR/YeeO family multidrug/toxin efflux MATE transporter;
Pssm-ID: 182293 [Multi-domain] Cd Length: 478 Bit Score: 53.59 E-value: 1.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 19 MSVPNMLGILTVLGFNLVDTYFISKLGTEALAAI----SFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKAKVFLH 94
Cdd:PRK10189 34 LAVPIFIENLCVLLMGVLSTFLVSWLGKEAMAGVgladSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAARQSLV 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 95 DALLLTFILTAGLSLLGSLCIDPLFSllGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSLAAL 174
Cdd:PRK10189 114 IMTLFAVLLAVLIHFFGEQIIDLVAG--DATPEVKALALTYLELTVWSYPAAAITLIGSGALRGAGNTKIPLLINGGMNI 191
|
170 180 190
....*....|....*....|....*....|.
gi 655375171 175 INLILDPLLIFGIGPFPRLEIQGAAVATLIS 205
Cdd:PRK10189 192 LNIIISSILIYGLFSWQGLGFVGAGLGLTIS 222
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
247-437 |
1.21e-06 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 50.40 E-value: 1.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 247 PAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVL 326
Cdd:cd12082 3 PLLLSMLLQTLYNLVDTFFLGRLLGDALAAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIVLAI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 327 LFQTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLFLLMLPLA 406
Cdd:cd12082 83 LLGLLLAALLLFFSPLILSLLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSNLLNILLDP 162
|
170 180 190
....*....|....*....|....*....|....*
gi 655375171 407 AL----GAFLGGVKGLMLALPVTNILMGIASYYLA 437
Cdd:cd12082 163 LLifglGPPELGIAGAALATVISYVIGALLLLIYL 197
|
|
| PRK00187 |
PRK00187 |
NorM family multidrug efflux MATE transporter; |
15-411 |
4.11e-06 |
|
NorM family multidrug efflux MATE transporter;
Pssm-ID: 166843 [Multi-domain] Cd Length: 464 Bit Score: 48.97 E-value: 4.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 15 VLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHAPKAKVFLH 94
Cdd:PRK00187 11 AILRLAGPLIASQLAHMLMVFTDTLMMGRLGPEALAGGGLGAASYSFVSIFCVGVIAAVGTLVAIRHGAGDIEGATRLAQ 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 95 DALLltfiLTAGLSLLGSLCI---DPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSL 171
Cdd:PRK00187 91 AGLW----LAWLLALVAALLLwnlKPLLLLFGQAPQNVDAAMQFLHLLPFALPGYLSFMALRGFTSALGRAGPVMVISLA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 172 AALINLILDPLLIFGIGPFPRLEIQG-AAVATLISWLVALSLSSYllvVKRHMLVAAGWCFSRFAD-NW---KQLAHIAQ 246
Cdd:PRK00187 167 GAVANLLLNYALIEGWFGLPKLGLMGiGLVTALVSNGMALALALY---IRRHPAYAAYPLRKGLSRpSRaalRELWRLGL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 247 PAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVL 326
Cdd:PRK00187 244 PIGGTYAVEVGLFTFAALCMGALGSTQLAAHQIALQIVSVAFMVPVGLSYAVTMRVGQHYGAGRLLEARRAGRVGIGFGA 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 327 LFqTLLYIPLALLAP-QIAALF--STDPQVLEWLSFYV-LVLPAAYGPL--GVVIIVATSLNAYHRPMASLVLNLCRLFL 400
Cdd:PRK00187 324 VV-MLLFAGLFWLLPeAIIGLFldRNDPAFAEIVQLAVsLLAVAAWFELfdGTQTIAMGAIRGLKDARTTFLIGLACYWL 402
|
410
....*....|.
gi 655375171 401 LMLPLAALGAF 411
Cdd:PRK00187 403 VGAPLAWLLAF 413
|
|
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
39-434 |
6.48e-05 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 44.94 E-value: 6.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 39 YFISKLGTEALAAISFTFPVTLVVSSIAigiGAGVSTNLGRLIGAGHAPKAKVFLHDALLLTFILTAGLSLLGSLCIDPL 118
Cdd:COG2244 28 LLARLLGPEEYGLFALALSIVALLSVLA---DLGLSTALVRFIAEYREEELRRLLSTALLLRLLLSLLLALLLLLLAPFI 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 119 FSLLGAkddilPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSLAALINLILDPLLIFGIGPFprleiqga 198
Cdd:COG2244 105 AALLGE-----PELALLLLLLALALLLSALSAVLLALLRGLERFKLLALINILSSLLSLLLALLLALLGLGL-------- 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 199 avatlisWLVALSLSSYLLVvkrhmlvaagwcfsrfadnwkqlahiaqpAALMNMINPLANAAIMGMLAriDHAAVAAFG 278
Cdd:COG2244 172 -------WGLVLKYSLPLLL-----------------------------SGLLGLLLTNLDRLLLGALL--GPAAVGIYS 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 279 AGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVLLFQTLLYIPLALLAPQIAALFSTDPQVLEWLS 358
Cdd:COG2244 214 AAYRLASLLLLLITALSQVLFPRLSRLLAEGDREELRRLYRKALRLLLLLGLPLALGLALLAPPLLSLLFGPEYAEAAPV 293
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 655375171 359 FYVLVLpaAYGPLGVVIIVATSLNAYHRPMASLVLNLCRLfLLMLPLAALGAFLGGVKGLMLALPVTNILMGIASY 434
Cdd:COG2244 294 LPILAL--GALFLALSGVLSNLLLALGRTRLLLIISLIGA-VLNLVLNLLLIPRYGLVGAAIATLLSYLVLLLLLL 366
|
|
| MurJ |
COG0728 |
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope ... |
16-303 |
6.61e-05 |
|
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440492 [Multi-domain] Cd Length: 503 Bit Score: 45.14 E-value: 6.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 16 LLNMSVPNMLGILTVLGFNLVDTYFISKLGTEALAAIS-----FTFPVTLvvssIAIGIGAGVSTNLGRLIGAGHAPKAK 90
Cdd:COG0728 224 VLKLMLPALLGVSVSQINLLVDTILASFLPEGSVSALYyadrlYQLPLGL----FGVAIGTALLPRLSRAAAAGDLEEFR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 91 VFLHDALLLTFILTAGLSLLGSLCIDPLFSLL---GAKDDILPLVHEYMNLWY-LGAPLLVVLMVGNQGLRATGDTRSPA 166
Cdd:COG0728 300 RTLSRGLRLVLLLTLPAAVGLIVLAEPIVRLLferGAFTAEDTALTALALAAYaLGLPAFALVKVLARAFYARQDTRTPV 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 167 AILSLAALINLILDPLLIfgigpfPRLEIQGAAVATLISWLVALSLSSYLLvvkrhmlvaagwcfsrfadnWKQLAHIAQ 246
Cdd:COG0728 380 RIAVIAVVVNIVLNLLLV------PPLGHAGLALATSLSALVNALLLLVLL--------------------RRRLGGLPL 433
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 655375171 247 PAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIA 303
Cdd:COG0728 434 RGILRTLLKLLLASLVMGAVLWLLLRLLGDWLGGGLLGRLLALALLILVGAAVYFAL 490
|
|
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
14-217 |
1.58e-04 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 43.68 E-value: 1.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 14 RVLLNMSVPNMLGILTVLGFNLVDTYFISK-LGTEALAAISFTFPVTLVVSSIAIGIGAGVSTNLGRLIGAGHApKAKVF 92
Cdd:cd13128 206 KELLRFSIPLALSGIFSLIYTRIDTIMLGYfLGDAAVGIYNAAYRIAELLLFIPSAISTALFPRISELYKNDKD-ELKKL 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 93 LHDALLLTFILTAGLSLLGSLCIDPLFSLLgAKDDILPLVhEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSPAAILSLA 172
Cdd:cd13128 285 LKKSFKYLFLISLPIAIGLFLFAEPIITLL-FGEEYLPAA-LVLQILAWGFLFIFLNGIFGSILQAIGKQKLTLKILLIG 362
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 655375171 173 ALINLILDPLLIfgigpfPRLEIQGAAVATLISWLVALSLSSYLL 217
Cdd:cd13128 363 ALLNVILNLLLI------PKYGIIGAAIATLISEFIIFILLLYLL 401
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
239-400 |
7.55e-04 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 41.89 E-value: 7.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 239 KQLAHIAQPAALMNMINPLANAAIMGMLARIDHAAVAAFGAGTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREAL 318
Cdd:cd13135 1 KKINHIAIPLILQNLVSQLQMLVDRAFLGRISIRYYSAVGNVTTPFNTITGFLGSISIGFTILGSQSVGAKDIKRINDYA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 319 LLALKFVLLFQTLLYIPLALLAPQIAALFSTDPQVLEWLSFYVLVLPAAYGPLGVVIIVATSLNAYHRP----MASLVLN 394
Cdd:cd13135 81 ISSIVYNSIIGVILFLLWLFGARIIFVLFGVDGQILGYSINYVRIFSIYLLLLGILFTFSSILQGIGETkpimYGGIIKN 160
|
....*.
gi 655375171 395 LCRLFL 400
Cdd:cd13135 161 LLNVIL 166
|
|
| PRK10367 |
PRK10367 |
DNA-damage-inducible SOS response protein; Provisional |
14-239 |
2.57e-03 |
|
DNA-damage-inducible SOS response protein; Provisional
Pssm-ID: 182413 [Multi-domain] Cd Length: 441 Bit Score: 40.11 E-value: 2.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 14 RVLLNMSVPNMLGILTVLGFNLVDTYFISKLGTEAL--------AAISFTFPVTLVVSSIAIGIGAgvstnlgRLIGAGH 85
Cdd:PRK10367 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVYlggvavgaTATSFLFMLLLFLRMSTTGLTA-------QAFGAKN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 86 APKAKVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMNLWYLGAPLLVVLMVGNQGLRATGDTRSP 165
Cdd:PRK10367 82 PQALARALVQPLLLALGAGALIALLRTPLIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAP 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 655375171 166 AAILSLAALINLILDPLLIFGIGpfprLEIQGAAVATLISWLVALSLSsylLVVKRHMLVAAGWCFSRFADNWK 239
Cdd:PRK10367 162 VILLVVGNILNIVLDLWLVMGLH----MNVQGAALATVIAEYATLLIG---LLMVRKVLKLRGISLEMLKTAWR 228
|
|
| MATE_SpoVB_like |
cd13124 |
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related ... |
12-217 |
7.78e-03 |
|
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240529 [Multi-domain] Cd Length: 434 Bit Score: 38.60 E-value: 7.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 12 IGRVLLNMSVPNMLGILTVLGFNLVDTYFISKL-----GTEALAAISF------TFPVTLVVSSIAIGIGAGVSTNLGRL 80
Cdd:cd13124 222 ILKELLSYAIPITLSSLILPLLQLIDSFTVPRRlqaagLSESEATALYgiltgrAQPLVQLPTVIATALSTSLVPAISEA 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 81 IGAGHAPKAKVFLHDALLLTFILTAGLSLLGSLCIDPLFSLLGAKDDILPLVHEYMnlwyLGAPLLVVLMVGNQGLRATG 160
Cdd:cd13124 302 YAKGDKKELRRRINQALRLTLLIGLPAAVGLAVLAEPINTLLFGDSEGGLILQILA----PSILFLSLQQVTAAILQGLG 377
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 655375171 161 DTRSPAAILSLAALINLILDPLLIfgigpfPRLEIQGAAVATLISWLVALSLSSYLL 217
Cdd:cd13124 378 KVKIPVINLLIGLLVKIVLNYVLI------PIFGIYGAAIATVIGFLVAALLNLRAL 428
|
|
| MATE_SpoVB_like |
cd13124 |
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related ... |
197-432 |
7.98e-03 |
|
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240529 [Multi-domain] Cd Length: 434 Bit Score: 38.60 E-value: 7.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 197 GAAVATLISWLVALSLSSYLLVVKRHMLVAAGWCFSRFADNW----KQLAHIAQPAALMNMINPLANAA----IMGMLAR 268
Cdd:cd13124 178 GATFGAVIGALAGLLVLLYYYRKKRRELKRLLRKSPRSKISTkeilKELLSYAIPITLSSLILPLLQLIdsftVPRRLQA 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 269 I---DHAAVAAFGA----GTRLESLLLIVVMGLSSSLVPFIAQNLGAGQKERAREALLLALKFVllfqTLLYIP----LA 337
Cdd:cd13124 258 AglsESEATALYGIltgrAQPLVQLPTVIATALSTSLVPAISEAYAKGDKKELRRRINQALRLT----LLIGLPaavgLA 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655375171 338 LLAPQIAALFSTDP---QVLEWLSFYVLvlpaaygPLGVVIIVAT---SLNAYHRPMASLVLNLCRLFLLMLPLAALGAF 411
Cdd:cd13124 334 VLAEPINTLLFGDSeggLILQILAPSIL-------FLSLQQVTAAilqGLGKVKIPVINLLIGLLVKIVLNYVLIPIFGI 406
|
250 260
....*....|....*....|.
gi 655375171 412 LGGVKGLMLALPVTNILMGIA 432
Cdd:cd13124 407 YGAAIATVIGFLVAALLNLRA 427
|
|
| |
