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Conserved domains on  [gi|657054004|ref|WP_029296791|]
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MULTISPECIES: ABC transporter ATP-binding protein [Pseudomonas]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11467437)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including Fe(3+) ions and polyamines such as spermidine and putrescine

CATH:  3.40.50.300
EC:  7.-.-.-
Gene Ontology:  GO:0042626|GO:0140359|GO:0005524|GO:0016887
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 7-363 0e+00

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


:

Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 524.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   7 NDVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIG 86
Cdd:COG3842    2 AMPALELENVSKRY-GDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 MVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMD 166
Cdd:COG3842   81 MVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLD 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 167 EPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENN 246
Cdd:COG3842  161 EPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEAN 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 247 RLNGRLHSHTGERcvVELArGEKVEALAVNVGQIGGPVTLSVRPERVSLngSSESCSNRFSGRVAEFIYLGDHVRVRLEV 326
Cdd:COG3842  241 LLPGTVLGDEGGG--VRTG-GRTLEVPADAGLAAGGPVTVAIRPEDIRL--SPEGPENGLPGTVEDVVFLGSHVRYRVRL 315

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 657054004 327 CGKADFFVKQPIAELDPaLTVGDVVPIGWQVEHVRAL 363
Cdd:COG3842  316 GDGQELVVRVPNRAALP-LEPGDRVGLSWDPEDVVVL 351
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 7-363 0e+00

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 524.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   7 NDVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIG 86
Cdd:COG3842    2 AMPALELENVSKRY-GDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 MVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMD 166
Cdd:COG3842   81 MVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLD 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 167 EPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENN 246
Cdd:COG3842  161 EPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEAN 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 247 RLNGRLHSHTGERcvVELArGEKVEALAVNVGQIGGPVTLSVRPERVSLngSSESCSNRFSGRVAEFIYLGDHVRVRLEV 326
Cdd:COG3842  241 LLPGTVLGDEGGG--VRTG-GRTLEVPADAGLAAGGPVTVAIRPEDIRL--SPEGPENGLPGTVEDVVFLGSHVRYRVRL 315

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 657054004 327 CGKADFFVKQPIAELDPaLTVGDVVPIGWQVEHVRAL 363
Cdd:COG3842  316 GDGQELVVRVPNRAALP-LEPGDRVGLSWDPEDVVVL 351
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 11-243 3.84e-147

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 415.10  E-value: 3.84e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGEnLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQ 90
Cdd:cd03300    1 IELENVSKFYGGF-VALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRPVNTVFQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:cd03300   80 NYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLG 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 171 ALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIG 243
Cdd:cd03300  160 ALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1-355 3.40e-136

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 393.16  E-value: 3.40e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   1 MSEVDSNDVLVSFRGVQKSYDGeNLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP 80
Cdd:PRK09452   5 NKQPSSLSPLVELRGISKSFDG-KEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  81 HKRDIGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEP 160
Cdd:PRK09452  84 ENRHVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKP 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 161 QLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVAN 240
Cdd:PRK09452 164 KVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVAR 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 241 FIGENNRLNGRLHSHTGE-RCVVELARGEKV--EALAVNVGQIggpVTLSVRPERVSLNGSSE-SCSNRFSGRVAEFIYL 316
Cdd:PRK09452 244 FIGEINIFDATVIERLDEqRVRANVEGRECNiyVNFAVEPGQK---LHVLLRPEDLRVEEINDdEHAEGLIGYVRERNYK 320

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 657054004 317 G---DHVrVRLEVcGK----ADFFvkqpiAELDPAL--TVGDVVPIGW 355
Cdd:PRK09452 321 GmtlDSV-VELEN-GKmvmvSEFF-----NEDDPDFdhSLGQKVAVTW 361
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 42-363 5.36e-125

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 362.58  E-value: 5.36e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   42 LLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSER 121
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPPHLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPRAEIKPR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  122 VKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHD 201
Cdd:TIGR01187  81 VLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITFVFVTHD 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  202 QGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRLNGRLHSHTGERCV---VELARGEKVEALAVNVG 278
Cdd:TIGR01187 161 QEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINVFEATVIERKSEQVVlagVEGRRCDIYTDVPVEKD 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  279 QiggPVTLSVRPERVSLNGSSE-SCSNRFSGRVAEFIYLGD--HVRVRLEVCGKADFFVKQPIAELDPALTVGDVVPIGW 355
Cdd:TIGR01187 241 Q---PLHVVLRPEKIVIEEEDEaNSSNAIIGHVIDITYLGMtlEVHVRLETGQKVLVSEFFNEDDPHMSPSIGDRVGLTW 317


                  ....*...
gi 657054004  356 QVEHVRAL 363
Cdd:TIGR01187 318 HPGSEVVL 325
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
19-327 5.55e-96

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 289.67  E-value: 5.55e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  19 SYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQNYALFPHM 98
Cdd:NF040840   8 SKDWKEFKLRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLPPEKRGIAYVYQNYMLFPHK 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 TVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLRE 178
Cdd:NF040840  88 TVFENIAFGLKLRKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALDVQTRD 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 179 HMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRLNGRLHShTGE 258
Cdd:NF040840 168 ELIREMKRWHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVGFENIIEGVAEK-GGE 246

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657054004 259 RCVVElARGEKVEAlavnVGQIGGPVTLSVRPER--VSLNGSSESCSNRFSGRVAEFIYLGDHVRVRLEVC 327
Cdd:NF040840 247 GTILD-TGNIKIEL----PEEKKGKVRIGIRPEDitISTEKVKTSARNEFKGKVEEIEDLGPLVKLTLDVG 312
ABC_arch_GlcV NF040933
glucose ABC transporter ATP-binding protein GlcV;
27-322 3.52e-91

glucose ABC transporter ATP-binding protein GlcV;


Pssm-ID: 468866 [Multi-domain]  Cd Length: 357  Bit Score: 277.65  E-value: 3.52e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEI-----LLAGRSINNVPPHKRDIGMVFQNYALFPHMTVA 101
Cdd:NF040933  22 LDNVNLEIKSGEFFGILGPSGHGKTTFLRIIAGLEVPTDGEIyfddkLVASPGKIIVPPEDRNIGMVFQNWALYPNMTVF 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 102 ENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQ 181
Cdd:NF040933 102 DNIAFPLKIKKVPKDEIEKKVKEVAEILGISEVLDRYPRELSGGQQQRVALARALVKNPQVLLLDEPFSNLDARIRDSAR 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 182 MEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRLNGRLhshTGERCV 261
Cdd:NF040933 182 ALVKKIQRELKITTIIVSHDPADIFSLADRAGVINNGKFQQVGKPEEIYDNPANIFVARLIGDINLLEGKV---EEEGLV 258

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 262 VelarGEKVEALAVNVGQIGGPVTLSVRPERVSLNGSSESCSNRFS----GRVAEFIYLGDHVRV 322
Cdd:NF040933 259 D----GNDLKIPLPNPKLEAGEVIIGIRPEDIDISESDMRLPPGFVevgkGRVKVSSYAGGVFRV 319
ABC_ATP_SaoA NF040729
ABC transporter ATP-binding protein SaoA; SaoA is the ATP-binding subunit of an ABC ...
 11-220 6.10e-70

ABC transporter ATP-binding protein SaoA; SaoA is the ATP-binding subunit of an ABC transporter in which both the permease subunit SaoP, and the substrate-binding protein SaoB, are nearly always selenoproteins that were unrecognized as such until recently (2022). The SAO system is found in Clostridium difficile and various other anaerobic heterotrophs.


Pssm-ID: 468693 [Multi-domain]  Cd Length: 248  Bit Score: 219.61  E-value: 6.10e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDG---ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPhkrDIGM 87
Cdd:NF040729   2 LKIQNISKTFINnkkENEVLKDISFDVEEGEFVSLLGPSGCGKTTLLTIIAGFQNATSGEILVNGNEVTKPGP---DRGF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDE 167
Cdd:NF040729  79 VFQNYALFPWMTVKENIEYPMKQQKMPKQEREKRLNELLEMAQLTGKENLYPHQISGGMKQRTAVIRALACKPEVLLMDE 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 168 PLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVF--HQGEI 220
Cdd:NF040729 159 PLGAVDFQMRQILQEELESIWLKDKTTVLMVTHDVDEAVYLSDRVIVMsrDKGKI 213
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
25-212 1.68e-53

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 176.06  E-value: 1.68e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  25 LIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINN------VPPHKRDIGMVFQNYALFPHM 98
Cdd:NF038007  19 KVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVTNlsysqkIILRRELIGYIFQSFNLIPHL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 TVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALD-KQLR 177
Cdd:NF038007  99 SIFDNVALPLKYRGVAKKERIERVNQVLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPALLLADEPTGNLDsKNAR 178

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 657054004 178 EHMQmEIKHLHQRlGVTVVYVTHDQgEALTMSDRV 212
Cdd:NF038007 179 AVLQ-QLKYINQK-GTTIIMVTHSD-EASTYGNRI 210
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 27-168 5.13e-49

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 162.05  E-value: 5.13e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN--NVPPHKRDIGMVFQNYALFPHMTVAENL 104
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTddERKSLRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004  105 AFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQR----YPAQLSGGQQQRVALARALVFEPQLVLMDEP 168
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRpvgeRPGTLSGGQRQRVAIARALLTKPKLLLLDEP 148
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
27-212 3.86e-28

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 108.86  E-value: 3.86e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGrsinnvpphKRDIGMVFQnyalfpHMTVAEnlAF 106
Cdd:NF040873   8 LHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAG---------GARVAYVPQ------RSEVPD--SL 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 107 PLTVRG---------------LSKTDvSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGA 171
Cdd:NF040873  71 PLTVRDlvamgrwarrglwrrLTRDD-RAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTG 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 657054004 172 LDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRV 212
Cdd:NF040873 150 LDAESRERIIALLAEEHAR-GATVVVVTHDLELVRRADPCV 189
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
27-220 1.42e-17

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 84.41  E-value: 1.42e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINnvpPH----KRDIGMVFQNYALFPHMTVAE 102
Cdd:NF033858 282 VDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVD---AGdiatRRRVGYMSQAFSLYGELTVRQ 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 103 NLAfpLTVR--GLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLR--- 177
Cdd:NF033858 359 NLE--LHARlfHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARdmf 436

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 657054004 178 -EHMQmeikHLHQRLGVTVVYVTHDQGEALTmSDRVAVFHQGEI 220
Cdd:NF033858 437 wRLLI----ELSREDGVTIFISTHFMNEAER-CDRISLMHAGRV 475
GguA NF040905
sugar ABC transporter ATP-binding protein;
14-218 2.19e-12

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 67.89  E-value: 2.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYDGenliVK---DLNLDIRKGEFLTLLGPSGSGKTTsLM-MLAG------FEtptaGEILLAG-----RSINNv 78
Cdd:NF040905   5 RGITKTFPG----VKaldDVNLSVREGEIHALCGENGAGKST-LMkVLSGvyphgsYE----GEILFDGevcrfKDIRD- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  79 pPHKRDIGMVFQNYALFPHMTVAEN--LAFPLTVRGL-SKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARA 155
Cdd:NF040905  75 -SEALGIVIIHQELALIPYLSIAENifLGNERAKRGViDWNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKA 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 156 LVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQG 218
Cdd:NF040905 154 LSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDG 215
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
11-168 5.12e-12

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 67.46  E-value: 5.12e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNvPPHKRDIG---- 86
Cdd:NF033858   2 ARLEGVSHRY-GKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMAD-ARHRRAVCpria 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 -MVfQ----NyaLFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRyPA-QLSGGQQQRVALARALVFEP 160
Cdd:NF033858  80 yMP-QglgkN--LYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADR-PAgKLSGGMKQKLGLCCALIHDP 155


                 ....*...
gi 657054004 161 QLVLMDEP 168
Cdd:NF033858 156 DLLILDEP 163
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
11-233 7.03e-12

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 65.91  E-value: 7.03e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSlMMLAGFETPTAGEILLAGRS-INNVPPHKRDIGMVF 89
Cdd:NF000106  14 VEVRGLVKHF-GEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRRPWRF*TwCANRRALRRTIG*HR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 Q-NYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEP 168
Cdd:NF000106  92 PvR*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEP 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 657054004 169 LGALDKQLREHMQMEIKHLhQRLGVTVVYVTHDQGEA------LTMSDRVAVFHQGEIQQIAPP---RTLYEEP 233
Cdd:NF000106 172 TTGLDPRTRNEVWDEVRSM-VRDGATVLLTTQYMEEAeqlaheLTVIDRGRVIADGKVDELKTKvggRTLQIRP 244
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 36-217 3.40e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.07  E-value: 3.40e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    36 KGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGrsinnvpphkrdigmvfqnyalfphmtvaenlafpltvrglsk 115
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYID------------------------------------------- 37

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   116 tdvSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEI-----KHLHQR 190
Cdd:smart00382  38 ---GEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEelrllLLLKSE 114

                          170       180
                   ....*....|....*....|....*..
gi 657054004   191 LGVTVVYVTHDQGEALTMSDRVAVFHQ 217
Cdd:smart00382 115 KNLTVILTTNDEKDLGPALLRRRFDRR 141
GguA NF040905
sugar ABC transporter ATP-binding protein;
23-220 2.04e-07

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 52.48  E-value: 2.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  23 ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAG--FETPTAGEILLAGRSI--NNVPphkRDI--GMVF-----QN 91
Cdd:NF040905 272 ERKVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGrsYGRNISGTVFKDGKEVdvSTVS---DAIdaGLAYvtedrKG 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  92 YALFPHMTVAENLAFPlTVRGLSK---------TDVSERVKRVLSMVQLDAFAQryPAQLSGGQQQRVALARALVFEPQL 162
Cdd:NF040905 349 YGLNLIDDIKRNITLA-NLGKVSRrgvideneeIKVAEEYRKKMNIKTPSVFQK--VGNLSGGNQQKVVLSKWLFTDPDV 425

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 163 VLMDEP-----LGAldkqlrehmQMEIKHLHQRL---GVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:NF040905 426 LILDEPtrgidVGA---------KYEIYTIINELaaeGKGVIVISSELPELLGMCDRIYVMNEGRI 482
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 7-363 0e+00

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 524.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   7 NDVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIG 86
Cdd:COG3842    2 AMPALELENVSKRY-GDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 MVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMD 166
Cdd:COG3842   81 MVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLD 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 167 EPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENN 246
Cdd:COG3842  161 EPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEAN 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 247 RLNGRLHSHTGERcvVELArGEKVEALAVNVGQIGGPVTLSVRPERVSLngSSESCSNRFSGRVAEFIYLGDHVRVRLEV 326
Cdd:COG3842  241 LLPGTVLGDEGGG--VRTG-GRTLEVPADAGLAAGGPVTVAIRPEDIRL--SPEGPENGLPGTVEDVVFLGSHVRYRVRL 315

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 657054004 327 CGKADFFVKQPIAELDPaLTVGDVVPIGWQVEHVRAL 363
Cdd:COG3842  316 GDGQELVVRVPNRAALP-LEPGDRVGLSWDPEDVVVL 351
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 11-365 4.34e-156

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 442.59  E-value: 4.34e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQ 90
Cdd:COG3839    4 LELENVSKSY-GGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKDRNIAMVFQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:COG3839   83 SYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDEPLS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 171 ALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGEN--NRL 248
Cdd:COG3839  163 NLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEELYDRPANLFVAGFIGSPpmNLL 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 249 NGRLHSHTgercvVELArGEKVEALAVNVGQIGGPVTLSVRPERVSLngsSESCSNRFSGRVAEFIYLGDHVRVRLEVcG 328
Cdd:COG3839  243 PGTVEGGG-----VRLG-GVRLPLPAALAAAAGGEVTLGIRPEHLRL---ADEGDGGLEATVEVVEPLGSETLVHVRL-G 312

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 657054004 329 KADFFVKQPIaelDPALTVGDVVPIGWQVEHVRALDP 365
Cdd:COG3839  313 GQELVARVPG---DTRLRPGDTVRLAFDPERLHLFDA 346
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 11-243 3.84e-147

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 415.10  E-value: 3.84e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGEnLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQ 90
Cdd:cd03300    1 IELENVSKFYGGF-VALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRPVNTVFQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:cd03300   80 NYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLG 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 171 ALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIG 243
Cdd:cd03300  160 ALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1-355 3.40e-136

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 393.16  E-value: 3.40e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   1 MSEVDSNDVLVSFRGVQKSYDGeNLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP 80
Cdd:PRK09452   5 NKQPSSLSPLVELRGISKSFDG-KEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  81 HKRDIGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEP 160
Cdd:PRK09452  84 ENRHVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKP 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 161 QLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVAN 240
Cdd:PRK09452 164 KVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVAR 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 241 FIGENNRLNGRLHSHTGE-RCVVELARGEKV--EALAVNVGQIggpVTLSVRPERVSLNGSSE-SCSNRFSGRVAEFIYL 316
Cdd:PRK09452 244 FIGEINIFDATVIERLDEqRVRANVEGRECNiyVNFAVEPGQK---LHVLLRPEDLRVEEINDdEHAEGLIGYVRERNYK 320

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 657054004 317 G---DHVrVRLEVcGK----ADFFvkqpiAELDPAL--TVGDVVPIGW 355
Cdd:PRK09452 321 GmtlDSV-VELEN-GKmvmvSEFF-----NEDDPDFdhSLGQKVAVTW 361
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 14-360 2.03e-127

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 369.48  E-value: 2.03e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYDGENLiVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN-NVPPHKRDIGMVFQNY 92
Cdd:COG1118    6 RNISKRFGSFTL-LDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFtNLPPRERRVGFVFQHY 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  93 ALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGAL 172
Cdd:COG1118   85 ALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEPFGAL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 173 DKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRLNGRl 252
Cdd:COG1118  165 DAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPATPFVARFLGCVNVLRGR- 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 253 hshtgercvvelARGEKVEA----LAVNVGQIGGPVTLSVRPERVSLnGSSESCSNRFSGRVAEFIYLGDHVRVRLEVCG 328
Cdd:COG1118  244 ------------VIGGQLEAdgltLPVAEPLPDGPAVAGVRPHDIEV-SREPEGENTFPATVARVSELGPEVRVELKLED 310

                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 657054004 329 KADffvkQPI-AELDPA------LTVGDVVPIGWQVEHV 360
Cdd:COG1118  311 GEG----QPLeAEVTKEawaelgLAPGDPVYLRPRPARV 345
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 42-363 5.36e-125

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 362.58  E-value: 5.36e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   42 LLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSER 121
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPPHLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPRAEIKPR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  122 VKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHD 201
Cdd:TIGR01187  81 VLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITFVFVTHD 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  202 QGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRLNGRLHSHTGERCV---VELARGEKVEALAVNVG 278
Cdd:TIGR01187 161 QEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINVFEATVIERKSEQVVlagVEGRRCDIYTDVPVEKD 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  279 QiggPVTLSVRPERVSLNGSSE-SCSNRFSGRVAEFIYLGD--HVRVRLEVCGKADFFVKQPIAELDPALTVGDVVPIGW 355
Cdd:TIGR01187 241 Q---PLHVVLRPEKIVIEEEDEaNSSNAIIGHVIDITYLGMtlEVHVRLETGQKVLVSEFFNEDDPHMSPSIGDRVGLTW 317


                  ....*...
gi 657054004  356 QVEHVRAL 363
Cdd:TIGR01187 318 HPGSEVVL 325
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 7-326 1.96e-118

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 347.02  E-value: 1.96e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    7 NDVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIG 86
Cdd:TIGR03265   1 SSPYLSIDNIRKRF-GAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRLPPQKRDYG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   87 MVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMD 166
Cdd:TIGR03265  80 IVFQSYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLLD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  167 EPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENN 246
Cdd:TIGR03265 160 EPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGEVN 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  247 RLNGRLHSHTgercvvELARGEKVEALAVNVGQIGGPVTLSVRPERVSLNGSSEScSNRFSGRVAEFIYLGDHVRVRLEV 326
Cdd:TIGR03265 240 WLPGTRGGGS------RARVGGLTLACAPGLAQPGASVRLAVRPEDIRVSPAGNA-ANLLLARVEDMEFLGAFYRLRLRL 312
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 11-224 9.28e-115

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 332.18  E-value: 9.28e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQ 90
Cdd:cd03259    1 LELKGLSKTY-GSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPERRNIGMVFQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:cd03259   80 DYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLS 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 657054004 171 ALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIA 224
Cdd:cd03259  160 ALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
11-291 1.92e-113

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 334.50  E-value: 1.92e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQ 90
Cdd:PRK11650   4 LKLQAVRKSYDGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPADRDIAMVFQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:PRK11650  84 NYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFLFDEPLS 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 171 ALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGEN--NRL 248
Cdd:PRK11650 164 NLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEVYEKPASTFVASFIGSPamNLL 243

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 657054004 249 NGRLhshTGERCVVELARGEKVEALAVNVGQIGGPVTLSVRPE 291
Cdd:PRK11650 244 DGRV---SADGAAFELAGGIALPLGGGYRQYAGRKLTLGIRPE 283
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 11-224 3.58e-108

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 315.73  E-value: 3.58e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQ 90
Cdd:cd03301    1 VELENVTKRF-GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKDRDIAMVFQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:cd03301   80 NYALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLS 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 657054004 171 ALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIA 224
Cdd:cd03301  160 NLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
6-346 7.21e-105

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 312.42  E-value: 7.21e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   6 SNDVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDI 85
Cdd:PRK11432   2 TQKNFVVLKNITKRF-GSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQRDI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 GMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLM 165
Cdd:PRK11432  81 CMVFQSYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 166 DEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGEN 245
Cdd:PRK11432 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRFMASFMGDA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 246 NRLNGRLHSHTgercvVELARGEKVEALAVNVGQIGGPVTLSVRPERVSLN---GSSESCSnrfsgrVAEFIYLGDHVRV 322
Cdd:PRK11432 241 NIFPATLSGDY-----VDIYGYRLPRPAAFAFNLPDGECTVGVRPEAITLSeqgEESQRCT------IKHVAYMGPQYEV 309

                        330       340
                 ....*....|....*....|....
gi 657054004 323 RLEVCGKaDFFVKQPIAELDPALT 346
Cdd:PRK11432 310 TVDWHGQ-ELLLQVNATQLQPDLG 332
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
11-354 2.39e-103

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 309.27  E-value: 2.39e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQ 90
Cdd:PRK11000   4 VTLRNVTKAY-GDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAERGVGMVFQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:PRK11000  83 SYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 171 ALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIG--ENNRL 248
Cdd:PRK11000 163 NLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPANRFVAGFIGspKMNFL 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 249 NGRLHSHTGERCVVELARGEK----VEALAVNVGQiggPVTLSVRPERVSlngSSESCSNRFSGRVAEFIYLGDHVRVRL 324
Cdd:PRK11000 243 PVKVTATAIEQVQVELPNRQQvwlpVEGRGVQVGA---NMSLGIRPEHLL---PSDIADVTLEGEVQVVEQLGNETQIHI 316

                        330       340       350
                 ....*....|....*....|....*....|.
gi 657054004 325 EVCG-KADFFVKQPIAELdpaLTVGDVVPIG 354
Cdd:PRK11000 317 QIPAiRQNLVYRQNDVVL---VEEGATFAIG 344
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
10-323 1.73e-102

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 307.15  E-value: 1.73e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGENlIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVF 89
Cdd:PRK11607  19 LLEIRNLTKSFDGQH-AVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQRPINMMF 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 QNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPL 169
Cdd:PRK11607  98 QSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPM 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 170 GALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRLN 249
Cdd:PRK11607 178 GALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFE 257

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 250 GRLHSHTGERCVVE---LARGEKVEALAVNVGqiGGPVTLSVRPERVSL-NGSSESCSNRFSGRVAEFIYLGD----HVR 321
Cdd:PRK11607 258 GVLKERQEDGLVIDspgLVHPLKVDADASVVD--NVPVHVALRPEKIMLcEEPPADGCNFAVGEVIHIAYLGDlsiyHVR 335


                 ..
gi 657054004 322 VR 323
Cdd:PRK11607 336 LK 337
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 13-253 9.31e-102

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 302.78  E-value: 9.31e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  13 FRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGMVFQ 90
Cdd:COG1125    4 FENVTKRYPDGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRDLDPVElrRRIGYVIQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAfplTV---RGLSKTDVSERVKRVLSMVQLDA--FAQRYPAQLSGGQQQRVALARALVFEPQLVLM 165
Cdd:COG1125   84 QIGLFPHMTVAENIA---TVprlLGWDKERIRARVDELLELVGLDPeeYRDRYPHELSGGQQQRVGVARALAADPPILLM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 166 DEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGEn 245
Cdd:COG1125  161 DEPFGALDPITREQLQDELLRLQRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILANPANDFVADFVGA- 239


                 ....*...
gi 657054004 246 NRLNGRLH 253
Cdd:COG1125  240 DRGLRRLS 247
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-229 6.02e-101

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 298.93  E-value: 6.02e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   1 MSevdSNDVLVSFRGVQKSY---DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINN 77
Cdd:COG1116    1 MS---AAAPALELRGVSKRFptgGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  78 VPPhkrDIGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALV 157
Cdd:COG1116   78 PGP---DRGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALA 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004 158 FEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVF--HQGEIQQI-----APPRTL 229
Cdd:COG1116  155 NDPEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVLsaRPGRIVEEidvdlPRPRDR 233
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 11-244 7.73e-99

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 293.09  E-value: 7.73e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQ 90
Cdd:cd03296    3 IEVRNVSKRF-GDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQERNVGFVFQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAFPLTVR----GLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMD 166
Cdd:cd03296   82 HYALFRHMTVFDNVAFGLRVKprseRPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLD 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 167 EPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGE 244
Cdd:cd03296  162 EPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSFLGE 239
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
19-327 5.55e-96

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 289.67  E-value: 5.55e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  19 SYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQNYALFPHM 98
Cdd:NF040840   8 SKDWKEFKLRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLPPEKRGIAYVYQNYMLFPHK 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 TVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLRE 178
Cdd:NF040840  88 TVFENIAFGLKLRKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALDVQTRD 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 179 HMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRLNGRLHShTGE 258
Cdd:NF040840 168 ELIREMKRWHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVGFENIIEGVAEK-GGE 246

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657054004 259 RCVVElARGEKVEAlavnVGQIGGPVTLSVRPER--VSLNGSSESCSNRFSGRVAEFIYLGDHVRVRLEVC 327
Cdd:NF040840 247 GTILD-TGNIKIEL----PEEKKGKVRIGIRPEDitISTEKVKTSARNEFKGKVEEIEDLGPLVKLTLDVG 312
3a0106s01 TIGR00968
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
 16-248 5.28e-95

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]


Pssm-ID: 130041 [Multi-domain]  Cd Length: 237  Bit Score: 283.23  E-value: 5.28e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   16 VQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQNYALF 95
Cdd:TIGR00968   6 ISKRF-GSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQPDSGRIRLNGQDATRVHARDRKIGFVFQHYALF 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   96 PHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQ 175
Cdd:TIGR00968  85 KHLTVRDNIAFGLEIRKHPKAKIKARVEELLELVQLEGLGDRYPNQLSGGQRQRVALARALAVEPQVLLLDEPFGALDAK 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004  176 LREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRL 248
Cdd:TIGR00968 165 VRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFVMSFLGEVNVL 237
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 11-215 1.78e-94

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 280.90  E-value: 1.78e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSY---DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPhkrDIGM 87
Cdd:cd03293    1 LEVRNVSKTYgggGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGP---DRGY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDE 167
Cdd:cd03293   78 VFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDE 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 657054004 168 PLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVF 215
Cdd:cd03293  158 PFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL 205
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 11-245 1.73e-93

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 279.57  E-value: 1.73e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGMV 88
Cdd:cd03295    1 IEFENVTKRYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVElrRKIGYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLD--AFAQRYPAQLSGGQQQRVALARALVFEPQLVLMD 166
Cdd:cd03295   81 IQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLDpaEFADRYPHELSGGQQQRVGVARALAADPPLLLMD 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004 167 EPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGEN 245
Cdd:cd03295  161 EPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEFVGAD 239
ABC_arch_GlcV NF040933
glucose ABC transporter ATP-binding protein GlcV;
27-322 3.52e-91

glucose ABC transporter ATP-binding protein GlcV;


Pssm-ID: 468866 [Multi-domain]  Cd Length: 357  Bit Score: 277.65  E-value: 3.52e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEI-----LLAGRSINNVPPHKRDIGMVFQNYALFPHMTVA 101
Cdd:NF040933  22 LDNVNLEIKSGEFFGILGPSGHGKTTFLRIIAGLEVPTDGEIyfddkLVASPGKIIVPPEDRNIGMVFQNWALYPNMTVF 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 102 ENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQ 181
Cdd:NF040933 102 DNIAFPLKIKKVPKDEIEKKVKEVAEILGISEVLDRYPRELSGGQQQRVALARALVKNPQVLLLDEPFSNLDARIRDSAR 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 182 MEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRLNGRLhshTGERCV 261
Cdd:NF040933 182 ALVKKIQRELKITTIIVSHDPADIFSLADRAGVINNGKFQQVGKPEEIYDNPANIFVARLIGDINLLEGKV---EEEGLV 258

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 262 VelarGEKVEALAVNVGQIGGPVTLSVRPERVSLNGSSESCSNRFS----GRVAEFIYLGDHVRV 322
Cdd:NF040933 259 D----GNDLKIPLPNPKLEAGEVIIGIRPEDIDISESDMRLPPGFVevgkGRVKVSSYAGGVFRV 319
PhnT TIGR03258
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ...
 22-365 5.20e-91

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.


Pssm-ID: 132302 [Multi-domain]  Cd Length: 362  Bit Score: 277.65  E-value: 5.20e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETP--TAGEILLAGRSINNVPPHKRDIGMVFQNYALFPHMT 99
Cdd:TIGR03258  16 GANTVLDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFVKAagLTGRIAIADRDLTHAPPHKRGLALLFQNYALFPHLK 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  100 VAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREH 179
Cdd:TIGR03258  96 VEDNVAFGLRAQKMPKADIAERVADALKLVGLGDAAAHLPAQLSGGMQQRIAIARAIAIEPDVLLLDEPLSALDANIRAN 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  180 MQMEIKHLHQRL-GVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRLNGRLHSHTGE 258
Cdd:TIGR03258 176 MREEIAALHEELpELTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDAPADGFAAEFLGAANILPAIALGITEA 255

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  259 RCVVELARGEKVEALAVNVGQIGGPVTLSVRPERVSLNGSSeSCSNRFSGRVAEFIYLGDHVRVRLEVCGKADF-FVKQP 337
Cdd:TIGR03258 256 PGLVDVSCGGAVIFAFGDGRHDGRDKLACIRPEHLALTPRP-AGEGRFHATIASVEWHGAALHLLCDLDAACDEpMLVTM 334

                         330       340
                  ....*....|....*....|....*...
gi 657054004  338 IAELDPALTVGDVVPIGWQVEHVRALDP 365
Cdd:TIGR03258 335 LRGRGPAPERGAKLALDCEADDAVLIEP 362
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
15-253 2.46e-89

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 272.73  E-value: 2.46e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  15 GVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQNYAL 94
Cdd:PRK10851   7 NIKKSF-GRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVFQHYAL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  95 FPHMTVAENLAFPLTV----RGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:PRK10851  86 FRHMTVFDNIAFGLTVlprrERPNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFG 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 171 ALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRLNG 250
Cdd:PRK10851 166 ALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFMGEVNRLQG 245


                 ...
gi 657054004 251 RLH 253
Cdd:PRK10851 246 TIR 248
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 19-246 3.93e-89

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 268.05  E-value: 3.93e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  19 SYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQNYALFPHM 98
Cdd:cd03299    7 SKDWKEFKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEKRDISYVPQNYALFPHM 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 TVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLRE 178
Cdd:cd03299   87 TVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKE 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 179 HMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENN 246
Cdd:cd03299  167 KLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFLGFNN 234
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
8-220 3.93e-79

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 242.26  E-value: 3.93e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   8 DVLVSFRGVQKSY---DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRD 84
Cdd:COG1136    2 SPLLELRNLTKSYgtgEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 ------IGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVF 158
Cdd:COG1136   82 rlrrrhIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVN 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 657054004 159 EPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQgEALTMSDRVAVFHQGEI 220
Cdd:COG1136  162 RPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDP-ELAARADRVIRLRDGRI 222
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 6-242 1.82e-78

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 241.04  E-value: 1.82e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   6 SNDVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRD- 84
Cdd:COG1127    1 MSEPMIEVRNLTKSF-GDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELYe 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 ----IGMVFQNYALFPHMTVAENLAFPLTVRG-LSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFE 159
Cdd:COG1127   80 lrrrIGMLFQGGALFDSLTVFENVAFPLREHTdLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALD 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 160 PQLVLMDEP--------LGALDkQLrehmqmeIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLyE 231
Cdd:COG1127  160 PEILLYDEPtagldpitSAVID-EL-------IRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEEL-L 230

                        250
                 ....*....|.
gi 657054004 232 EPKNTFVANFI 242
Cdd:COG1127  231 ASDDPWVRQFL 241
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 10-235 2.95e-77

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 237.58  E-value: 2.95e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN----NVPPHKRDI 85
Cdd:COG1126    1 MIEIENLHKSF-GDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTdskkDINKLRRKV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 GMVFQNYALFPHMTVAENLAF-PLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVL 164
Cdd:COG1126   80 GMVFQQFNLFPHLTVLENVTLaPIKVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVML 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 657054004 165 MDEPLGALDKQL-REHMQMeIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKN 235
Cdd:COG1126  160 FDEPTSALDPELvGEVLDV-MRDLAKE-GMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFENPQH 229
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 2-234 5.39e-76

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 243.27  E-value: 5.39e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   2 SEVDSNDVLVSFRGVQKSYD----GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINN 77
Cdd:COG1123  252 PAAAAAEPLLEVRNLSKRYPvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTK 331

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  78 VP-----PHKRDIGMVFQN--YALFPHMTVAENLAFPLTVRG-LSKTDVSERVKRVLSMVQLDA-FAQRYPAQLSGGQQQ 148
Cdd:COG1123  332 LSrrslrELRRRVQMVFQDpySSLNPRMTVGDIIAEPLRLHGlLSRAERRERVAELLERVGLPPdLADRYPHELSGGQRQ 411

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 149 RVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRT 228
Cdd:COG1123  412 RVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEE 491


                 ....*.
gi 657054004 229 LYEEPK 234
Cdd:COG1123  492 VFANPQ 497
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 27-242 1.06e-75

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 234.85  E-value: 1.06e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP------HKRDIGMVFQNYALFPHMTV 100
Cdd:cd03294   40 VNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRkelrelRRKKISMVFQSFALLPHRTV 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 101 AENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHM 180
Cdd:cd03294  120 LENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREM 199

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 657054004 181 QMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFI 242
Cdd:cd03294  200 QDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFF 261
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
11-221 2.63e-75

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 232.25  E-value: 2.63e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINN-----VPPHKRDI 85
Cdd:COG2884    2 IRFENVSKRYPGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRlkrreIPYLRRRI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 GMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLM 165
Cdd:COG2884   82 GVVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLA 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004 166 DEPLGALDKQLRehmqMEI-KHLHQ--RLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQ 221
Cdd:COG2884  162 DEPTGNLDPETS----WEImELLEEinRRGTTVLIATHDLELVDRMPKRVLELEDGRLV 216
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 13-219 3.21e-75

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 230.54  E-value: 3.21e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  13 FRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN----NVPPHKRDIGMV 88
Cdd:cd03229    3 LKNVSKRY-GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTdledELPPLRRRIGMV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQNYALFPHMTVAENLAFPltvrglsktdvservkrvlsmvqldafaqrypaqLSGGQQQRVALARALVFEPQLVLMDEP 168
Cdd:cd03229   82 FQDFALFPHLTVLENIALG----------------------------------LSGGQQQRVALARALAMDPDVLLLDEP 127

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 657054004 169 LGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGE 219
Cdd:cd03229  128 TSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 11-220 6.53e-74

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 228.53  E-value: 6.53e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSY---DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRD--- 84
Cdd:cd03255    1 IELKNLSKTYgggGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAafr 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 ---IGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQ 161
Cdd:cd03255   81 rrhIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004 162 LVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQgEALTMSDRVAVFHQGEI 220
Cdd:cd03255  161 IILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDP-ELAEYADRIIELRDGKI 218
ProV COG4175
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 27-275 1.12e-73

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443334 [Multi-domain]  Cd Length: 389  Bit Score: 233.84  E-value: 1.12e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK------RDIGMVFQNYALFPHMTV 100
Cdd:COG4175   43 VNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPTAGEVLIDGEDITKLSKKElrelrrKKMSMVFQHFALLPHRTV 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 101 AENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHM 180
Cdd:COG4175  123 LENVAFGLEIQGVPKAERRERAREALELVGLAGWEDSYPDELSGGMQQRVGLARALATDPDILLMDEAFSALDPLIRREM 202

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 181 QMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRLN----------- 249
Cdd:COG4175  203 QDELLELQAKLKKTIVFITHDLDEALRLGDRIAIMKDGRIVQIGTPEEILTNPANDYVADFVEDVDRSKvltagsvmrpp 282

                        250       260
                 ....*....|....*....|....*..
gi 657054004 250 -GRLHSHTGERCVVELARGEKVEALAV 275
Cdd:COG4175  283 eAVVSEKDGPRVALRRMREEGISSLYV 309
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 11-234 7.11e-71

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 221.05  E-value: 7.11e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGMV 88
Cdd:COG1122    1 IELENLSFSYPGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRElrRKVGLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQN--YALFpHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMD 166
Cdd:COG1122   81 FQNpdDQLF-APTVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLD 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 167 EPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPK 234
Cdd:COG1122  160 EPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDYE 226
proV TIGR01186
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...
 22-243 3.00e-70

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130254 [Multi-domain]  Cd Length: 363  Bit Score: 223.96  E-value: 3.00e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP------HKRDIGMVFQNYALF 95
Cdd:TIGR01186   4 GGKKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMKQSPvelrevRRKKIGMVFQQFALF 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   96 PHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQ 175
Cdd:TIGR01186  84 PHMTILQNTSLGPELLGWPEQERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSALDPL 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004  176 LREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIG 243
Cdd:TIGR01186 164 IRDSMQDELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIG 231
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 11-241 4.66e-70

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 219.30  E-value: 4.66e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK-----RDI 85
Cdd:cd03261    1 IELRGLTKSF-GGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAElyrlrRRM 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 GMVFQNYALFPHMTVAENLAFPLTVRG-LSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVL 164
Cdd:cd03261   80 GMLFQSGALFDSLTVFENVAFPLREHTrLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 165 MDEPLGALD-KQLREHMQMeIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPkNTFVANF 241
Cdd:cd03261  160 YDEPTAGLDpIASGVIDDL-IRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRASD-DPLVRQF 235
ABC_ATP_SaoA NF040729
ABC transporter ATP-binding protein SaoA; SaoA is the ATP-binding subunit of an ABC ...
 11-220 6.10e-70

ABC transporter ATP-binding protein SaoA; SaoA is the ATP-binding subunit of an ABC transporter in which both the permease subunit SaoP, and the substrate-binding protein SaoB, are nearly always selenoproteins that were unrecognized as such until recently (2022). The SAO system is found in Clostridium difficile and various other anaerobic heterotrophs.


Pssm-ID: 468693 [Multi-domain]  Cd Length: 248  Bit Score: 219.61  E-value: 6.10e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDG---ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPhkrDIGM 87
Cdd:NF040729   2 LKIQNISKTFINnkkENEVLKDISFDVEEGEFVSLLGPSGCGKTTLLTIIAGFQNATSGEILVNGNEVTKPGP---DRGF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDE 167
Cdd:NF040729  79 VFQNYALFPWMTVKENIEYPMKQQKMPKQEREKRLNELLEMAQLTGKENLYPHQISGGMKQRTAVIRALACKPEVLLMDE 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 168 PLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVF--HQGEI 220
Cdd:NF040729 159 PLGAVDFQMRQILQEELESIWLKDKTTVLMVTHDVDEAVYLSDRVIVMsrDKGKI 213
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
13-244 3.36e-69

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 216.93  E-value: 3.36e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  13 FRGVQKSYDGENLivkDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQNY 92
Cdd:COG3840    4 LDDLTYRYGDFPL---RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAERPVSMLFQEN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  93 ALFPHMTVAENLAFPLTVRG-LSKTDvSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGA 171
Cdd:COG3840   81 NLFPHLTVAQNIGLGLRPGLkLTAEQ-RAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSA 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 172 LDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGE 244
Cdd:COG3840  160 LDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYLGI 232
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 28-224 6.91e-69

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 215.62  E-value: 6.91e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  28 KDLNLDIR---KGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN------NVPPHKRDIGMVFQNYALFPHM 98
Cdd:cd03297   11 PDFTLKIDfdlNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFdsrkkiNLPPQQRKIGLVFQQYALFPHL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 TVAENLAFPLtvRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLRE 178
Cdd:cd03297   91 NVRENLAFGL--KRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRL 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 657054004 179 HMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIA 224
Cdd:cd03297  169 QLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 11-220 7.92e-69

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 215.47  E-value: 7.92e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH----KRDIG 86
Cdd:cd03262    1 IEIKNLHKSF-GDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNinelRQKVG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 MVFQNYALFPHMTVAENLAF-PLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLM 165
Cdd:cd03262   80 MVFQQFNLFPHLTVLENITLaPIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLF 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 166 DEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03262  160 DEPTSALDPELVGEVLDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFMDDGRI 213
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 29-326 1.46e-67

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 216.89  E-value: 1.46e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  29 DLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGR------SINNVPPHKRDIGMVFQNYALFPHMTVAE 102
Cdd:COG4148   17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEvlqdsaRGIFLPPHRRRIGYVFQEARLFPHLSVRG 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 103 NLAFpltvrGLSKTDVSER---VKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREH 179
Cdd:COG4148   97 NLLY-----GRKRAPRAERrisFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAE 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 180 MQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRLNGRLHSHTGER 259
Cdd:COG4148  172 ILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPDLLPLAGGEEAGSVLEATVAAHDPDY 251

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 260 CVVELARGEKVEALAVNVGQIGGPVTLSVRPERVSL-----NGSseSCSNRFSGRVAEFIYLGD-HVRVRLEV 326
Cdd:COG4148  252 GLTRLALGGGRLWVPRLDLPPGTRVRVRIRARDVSLaleppEGS--SILNILPGRVVEIEPADGgQVLVRLDL 322
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
11-232 2.55e-67

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 212.23  E-value: 2.55e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH-KRDIGMVF 89
Cdd:COG1131    1 IEVRGLTKRY-GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEvRRRIGYVP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 QNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPL 169
Cdd:COG1131   80 QEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPT 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 170 GALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEE 232
Cdd:COG1131  160 SGLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKAR 221
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 10-235 3.58e-66

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 209.66  E-value: 3.58e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYD---GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP--HKRD 84
Cdd:COG1124    1 MLEVRNLSVSYGqggRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRkaFRRR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 IGMVFQNY--ALFPHMTVAENLAFPLTVRGLskTDVSERVKRVLSMVQLD-AFAQRYPAQLSGGQQQRVALARALVFEPQ 161
Cdd:COG1124   81 VQMVFQDPyaSLHPRHTVDRILAEPLRIHGL--PDREERIAELLEQVGLPpSFLDRYPHQLSGGQRQRVAIARALILEPE 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 162 LVLMDEPLGALDKqlreHMQMEI----KHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKN 235
Cdd:COG1124  159 LLLLDEPTSALDV----SVQAEIlnllKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGPKH 232
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 10-220 9.58e-66

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 207.74  E-value: 9.58e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGENL---IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVP-----PH 81
Cdd:cd03257    1 LLEVKNLSVSFPTGGGsvkALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSrrlrkIR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  82 KRDIGMVFQNY--ALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQL---DAFAQRYPAQLSGGQQQRVALARAL 156
Cdd:cd03257   81 RKEIQMVFQDPmsSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAVLLLLVGVglpEEVLNRYPHELSGGQRQRVAIARAL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 657054004 157 VFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03257  161 ALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKI 224
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
1-214 5.33e-65

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 207.02  E-value: 5.33e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   1 MSEVDSNDVLVSFRGvqksYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNvPP 80
Cdd:COG4525    1 MSMLTVRHVSVRYPG----GGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTG-PG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  81 HKRdiGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEP 160
Cdd:COG4525   76 ADR--GVVFQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADP 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 657054004 161 QLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAV 214
Cdd:COG4525  154 RFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVEEALFLATRLVV 207
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 10-219 3.21e-63

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 200.94  E-value: 3.21e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   10 LVSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH-----KRD 84
Cdd:TIGR02673   1 MIEFHNVSKAYPGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRGRqlpllRRR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   85 IGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVL 164
Cdd:TIGR02673  81 IGVVFQDFRLLPDRTVYENVALPLEVRGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLL 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 657054004  165 MDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGE 219
Cdd:TIGR02673 161 ADEPTGNLDPDLSERILDLLKRLNKR-GTTVIVATHDLSLVDRVAHRVIILDDGR 214
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 12-219 3.73e-63

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 200.77  E-value: 3.73e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  12 SFRGVQKSY-DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGMV 88
Cdd:cd03225    1 ELKNLSFSYpDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKElrRKVGLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQN--YALFpHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMD 166
Cdd:cd03225   81 FQNpdDQFF-GPTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLD 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 657054004 167 EPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGE 219
Cdd:cd03225  160 EPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
10-242 3.81e-63

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 201.86  E-value: 3.81e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDI---- 85
Cdd:PRK09493   1 MIEFKNVSKHF-GPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERLIrqea 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 GMVFQNYALFPHMTVAENLAF-PLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVL 164
Cdd:PRK09493  80 GMVFQQFYLFPHLTALENVMFgPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLML 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 165 MDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFI 242
Cdd:PRK09493 160 FDEPTSALDPELRHEVLKVMQDLAEE-GMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQEFL 236
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 10-234 5.67e-63

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 200.89  E-value: 5.67e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYD---GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK---- 82
Cdd:cd03258    1 MIELKNVSKVFGdtgGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKElrka 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  83 -RDIGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQ 161
Cdd:cd03258   81 rRRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPK 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 162 LVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPK 234
Cdd:cd03258  161 VLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFANPQ 233
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
11-271 2.40e-62

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 203.00  E-value: 2.40e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSY---DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK----- 82
Cdd:COG1135    2 IELENLSKTFptkGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERElraar 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  83 RDIGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQL 162
Cdd:COG1135   82 RKIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPKV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 163 VLMDEPLGALDKQ--------LREhmqmeikhLHQRLGVTVVYVTHDqgealtMS------DRVAVFHQGEIQQIAPPRT 228
Cdd:COG1135  162 LLCDEATSALDPEttrsildlLKD--------INRELGLTIVLITHE------MDvvrricDRVAVLENGRIVEQGPVLD 227

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 657054004 229 LYEEPKNTFVANFIGE------NNRLNGRLHSHTGERCVVELA-RGEKVE 271
Cdd:COG1135  228 VFANPQSELTRRFLPTvlndelPEELLARLREAAGGGRLVRLTfVGESAD 277
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 10-234 7.44e-62

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 206.68  E-value: 7.44e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSY-DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTT---SLMMLAGFETPTAGEILLAGRSINNVPPHKR-- 83
Cdd:COG1123    4 LLEVRDLSVRYpGGDVPAVDGVSLTIAPGETVALVGESGSGKSTlalALMGLLPHGGRISGEVLLDGRDLLELSEALRgr 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  84 DIGMVFQN--YALFPhMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQ 161
Cdd:COG1123   84 RIGMVFQDpmTQLNP-VTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPD 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 162 LVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPK 234
Cdd:COG1123  163 LLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQ 235
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
12-220 1.03e-60

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 194.26  E-value: 1.03e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  12 SFRGVQKSYDGENlIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGMVF 89
Cdd:COG4619    2 ELEGLSFRVGGKP-ILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEwrRQVAYVP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 QNYALFPhMTVAENLAFPLTVRGLSKTDvsERVKRVLSMVQLDA-FAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEP 168
Cdd:COG4619   81 QEPALWG-GTVRDNLPFPFQLRERKFDR--ERALELLERLGLPPdILDKPVERLSGGERQRLALIRALLLQPDVLLLDEP 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 657054004 169 LGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:COG4619  158 TSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 10-220 2.18e-60

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 194.89  E-value: 2.18e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP-----HKRD 84
Cdd:COG3638    2 MLELRNLSKRYPGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGralrrLRRR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 IGMVFQNYALFPHMTVAEN--------LAFPLTVRGL-SKTDVsERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARA 155
Cdd:COG3638   82 IGMIFQQFNLVPRLSVLTNvlagrlgrTSTWRSLLGLfPPEDR-ERALEALERVGLADKAYQRADQLSGGQQQRVAIARA 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 156 LVFEPQLVLMDEPLGALDKQL-REHMQMeIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:COG3638  161 LVQEPKLILADEPVASLDPKTaRQVMDL-LRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGRV 225
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 11-229 1.25e-59

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 192.01  E-value: 1.25e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFE-----TPTAGEILLAGRSIN----NVPPH 81
Cdd:cd03260    1 IELRDLNVYY-GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNdlipgAPDEGEVLLDGKDIYdldvDVLEL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  82 KRDIGMVFQNYALFPhMTVAENLAFPLTVRG-LSKTDVSERVKRVLSMVQL-DAFAQRYPA-QLSGGQQQRVALARALVF 158
Cdd:cd03260   80 RRRVGMVFQKPNPFP-GSIYDNVAYGLRLHGiKLKEELDERVEEALRKAALwDEVKDRLHAlGLSGGQQQRLCLARALAN 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657054004 159 EPQLVLMDEPLGALDKQLREHMQMEIKHLHQRlgVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTL 229
Cdd:cd03260  159 EPEVLLLDEPTSALDPISTAKIEELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 22-222 1.60e-59

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 191.16  E-value: 1.60e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETP---TAGEILLAGRSINNVPPHKRDIGMVFQNYALFPHM 98
Cdd:COG4136   12 GGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLLNGRRLTALPAEQRRIGILFQDDLLFPHL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 TVAENLAFPLTvRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLRE 178
Cdd:COG4136   92 SVGENLAFALP-PTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAALRA 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 657054004 179 HM-QMEIKHLHQRlGVTVVYVTHDQGEALTMSdrvAVFHQGEIQQ 222
Cdd:COG4136  171 QFrEFVFEQIRQR-GIPALLVTHDEEDAPAAG---RVLDLGNWQH 211
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 11-242 1.46e-58

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 189.84  E-value: 1.46e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN--NVPPHK------ 82
Cdd:PRK11124   3 IQLNGINCFY-GAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDfsKTPSDKairelr 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  83 RDIGMVFQNYALFPHMTVAENL-AFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQ 161
Cdd:PRK11124  82 RNVGMVFQQYNLWPHLTVQQNLiEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQ 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 162 LVLMDEPLGALDKQLREHMQMEIKHLhQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIApPRTLYEEPKNTFVANF 241
Cdd:PRK11124 162 VLLFDEPTAALDPEITAQIVSIIREL-AETGITQVIVTHEVEVARKTASRVVYMENGHIVEQG-DASCFTQPQTEAFKNY 239


                 .
gi 657054004 242 I 242
Cdd:PRK11124 240 L 240
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
11-220 7.80e-58

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 187.91  E-value: 7.80e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN-NVPPH-------K 82
Cdd:COG4161    3 IQLKNINCFY-GSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFDfSQKPSekairllR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  83 RDIGMVFQNYALFPHMTVAENL-AFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQ 161
Cdd:COG4161   82 QKVGMVFQQYNLWPHLTVMENLiEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQ 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004 162 LVLMDEPLGALDKQLREHMQMEIKHLHQrLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:COG4161  162 VLLFDEPTAALDPEITAQVVEIIRELSQ-TGITQVIVTHEVEFARKVASQVVYMEKGRI 219
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 6-226 4.13e-57

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 185.72  E-value: 4.13e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   6 SNDVLVSFRGVQKSY---DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK 82
Cdd:COG4181    4 SSAPIIELRGLTKTVgtgAGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  83 R------DIGMVFQNYALFPHMTVAENLAFPLTVRGLSktDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARAL 156
Cdd:COG4181   84 RarlrarHVGFVFQSFQLLPTLTALENVMLPLELAGRR--DARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAF 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 157 VFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALtMSDRVAVFHQGEIQQIAPP 226
Cdd:COG4181  162 ATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAA-RCDRVLRLRAGRLVEDTAA 230
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 10-234 7.30e-57

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 187.95  E-value: 7.30e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGENLIVK---DLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETP---TAGEILLAGRSINNVPPHK- 82
Cdd:COG0444    1 LLEVRNLKVYFPTRRGVVKavdGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLLKLSEKEl 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  83 -----RDIGMVFQN-Y-ALFPHMTVAENLAFPLTV-RGLSKTDVSERVKRVLSMVQLD---AFAQRYPAQLSGGQQQRVA 151
Cdd:COG0444   81 rkirgREIQMIFQDpMtSLNPVMTVGDQIAEPLRIhGGLSKAEARERAIELLERVGLPdpeRRLDRYPHELSGGMRQRVM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 152 LARALVFEPQLVLMDEPLGALD--------KQLREhmqmeikhLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQI 223
Cdd:COG0444  161 IARALALEPKLLIADEPTTALDvtiqaqilNLLKD--------LQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEE 232

                        250
                 ....*....|.
gi 657054004 224 APPRTLYEEPK 234
Cdd:COG0444  233 GPVEELFENPR 243
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 29-329 4.21e-56

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 187.24  E-value: 4.21e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   29 DLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINN------VPPHKRDIGMVFQNYALFPHMTVAE 102
Cdd:TIGR02142  15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDsrkgifLPPEKRRIGYVFQEARLFPHLSVRG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  103 NLAFpltvrGLSKTDVSERV---KRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREH 179
Cdd:TIGR02142  95 NLRY-----GMKRARPSERRisfERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYE 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  180 MQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPkntfVANFIGENNR---LNGRLHSHT 256
Cdd:TIGR02142 170 ILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASP----DLPWLAREDQgslIEGVVAEHD 245

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004  257 GERCVVELARGEKVEALAVNVGQIGGPVTLSVRPERVSLNGS---SESCSNRFSGRVAEfIYLGD--HVRVRLEVCGK 329
Cdd:TIGR02142 246 QHYGLTALRLGGGHLWVPENLGPTGARLRLRVPARDVSLALQkpeATSIRNILPARVVE-IEDSDigRVGVVLESGGK 322
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 6-234 7.95e-56

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 185.71  E-value: 7.95e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   6 SNDVLVSFRGVQKSYD-GENLI---------VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSI 75
Cdd:COG4608    3 MAEPLLEVRDLKKHFPvRGGLFgrtvgvvkaVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  76 NNVPPHK-----RDIGMVFQN-YA-LFPHMTVAENLAFPLTVRGL-SKTDVSERVKRVLSMVQLDA-FAQRYPAQLSGGQ 146
Cdd:COG4608   83 TGLSGRElrplrRRMQMVFQDpYAsLNPRMTVGDIIAEPLRIHGLaSKAERRERVAELLELVGLRPeHADRYPHEFSGGQ 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 147 QQRVALARALVFEPQLVLMDEPLGALDK----Q----LREhmqmeikhLHQRLGVTVVYVTHDqgeaLTM----SDRVAV 214
Cdd:COG4608  163 RQRIGIARALALNPKLIVCDEPVSALDVsiqaQvlnlLED--------LQDELGLTYLFISHD----LSVvrhiSDRVAV 230

                        250       260
                 ....*....|....*....|
gi 657054004 215 FHQGEIQQIAPPRTLYEEPK 234
Cdd:COG4608  231 MYLGKIVEIAPRDELYARPL 250
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 27-227 1.03e-55

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 182.28  E-value: 1.03e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPhkrDIGMVFQNYALFPHMTVAENLAF 106
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGP---DRMVVFQNYSLLPWLTVRENIAL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  107 PL--TVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEI 184
Cdd:TIGR01184  78 AVdrVLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEEL 157

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 657054004  185 KHLHQRLGVTVVYVTHDQGEALTMSDRVAVF------HQGEIQQIAPPR 227
Cdd:TIGR01184 158 MQIWEEHRVTVLMVTHDVDEALLLSDRVVMLtngpaaNIGQILEVPFPR 206
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 11-220 1.59e-55

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 181.07  E-value: 1.59e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINN-----VPPHKRDI 85
Cdd:cd03292    1 IEFINVTKTYPNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDlrgraIPYLRRKI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 GMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLM 165
Cdd:cd03292   81 GVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIA 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 166 DEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03292  161 DEPTGNLDPDTTWEIMNLLKKINKA-GTTVVVATHAKELVDTTRHRVIALERGKL 214
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 11-229 2.38e-55

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 180.78  E-value: 2.38e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSY-DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH-KRDIGMV 88
Cdd:cd03263    1 LQIRNLTKTYkKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAaRQSLGYC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEP 168
Cdd:cd03263   81 PQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEP 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657054004 169 LGALDKQLREHMQMEIkhLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTL 229
Cdd:cd03263  161 TSGLDPASRRAIWDLI--LEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQEL 219
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 7-224 3.14e-55

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 181.78  E-value: 3.14e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   7 NDVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKR-DI 85
Cdd:COG0411    1 SDPLLEVRGLTKRF-GGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIaRL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 GMV--FQNYALFPHMTVAENLA---------------FPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQ 148
Cdd:COG0411   80 GIArtFQNPRLFPELTVLENVLvaaharlgrgllaalLRLPRARREEREARERAEELLERVGLADRADEPAGNLSYGQQR 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 149 RVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIqqIA 224
Cdd:COG0411  160 RLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRV--IA 233
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 28-234 4.03e-55

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 182.27  E-value: 4.03e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   28 KDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN-----NVPPHKRDIGMVFQN--YALFpHMTV 100
Cdd:TIGR04521  22 DDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITakkkkKLKDLRKKVGLVFQFpeHQLF-EETV 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  101 AENLAFPLTVRGLSKTDVSERVKRVLSMVQLD-AFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREH 179
Cdd:TIGR04521 101 YKDIAFGPKNLGLSEEEAEERVKEALELVGLDeEYLERSPFELSGGQMRRVAIAGVLAMEPEVLILDEPTAGLDPKGRKE 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 657054004  180 MQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPK 234
Cdd:TIGR04521 181 ILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSDVD 235
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 14-220 2.26e-54

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 179.49  E-value: 2.26e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEiLLAGrsinNVPPH--KRDIGMVFQN 91
Cdd:PRK11247  16 NAVSKRY-GERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGE-LLAG----TAPLAeaREDTRLMFQD 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  92 YALFPHMTVAENLAFPLtvrglsKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGA 171
Cdd:PRK11247  90 ARLLPWKKVIDNVGLGL------KGQWRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGA 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 657054004 172 LDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:PRK11247 164 LDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 14-220 6.17e-54

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 177.63  E-value: 6.17e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYDGenLI-VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKR---DIGMVF 89
Cdd:cd03219    4 RGLTKRFGG--LVaLDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIarlGIGRTF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 QNYALFPHMTVAENL----------AFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFE 159
Cdd:cd03219   82 QIPRLFPELTVLENVmvaaqartgsGLLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATD 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657054004 160 PQLVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03219  162 PKLLLLDEPAAGLNPEETEELAELIRELRER-GITVLLVEHDMDVVMSLADRVTVLDQGRV 221
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 11-227 8.79e-54

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 178.39  E-value: 8.79e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   11 VSFRGVQKSY-DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAG---RSINNVPPHKRDIG 86
Cdd:TIGR04520   1 IEVENVSFSYpESEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGldtLDEENLWEIRKKVG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   87 MVFQNyalfPH-----MTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQ 161
Cdd:TIGR04520  81 MVFQN----PDnqfvgATVEDDVAFGLENLGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPD 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004  162 LVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALtMSDRVAVFHQGEIQQIAPPR 227
Cdd:TIGR04520 157 IIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAV-LADRVIVMNKGKIVAEGTPR 221
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
25-212 1.68e-53

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 176.06  E-value: 1.68e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  25 LIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINN------VPPHKRDIGMVFQNYALFPHM 98
Cdd:NF038007  19 KVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVTNlsysqkIILRRELIGYIFQSFNLIPHL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 TVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALD-KQLR 177
Cdd:NF038007  99 SIFDNVALPLKYRGVAKKERIERVNQVLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPALLLADEPTGNLDsKNAR 178

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 657054004 178 EHMQmEIKHLHQRlGVTVVYVTHDQgEALTMSDRV 212
Cdd:NF038007 179 AVLQ-QLKYINQK-GTTIIMVTHSD-EASTYGNRI 210
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 14-245 1.80e-53

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 176.97  E-value: 1.80e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH-KRDIGMVFQNY 92
Cdd:COG4555    5 ENLSKKY-GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREaRRQIGVLPDER 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  93 ALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGAL 172
Cdd:COG4555   84 GLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNGL 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 173 DKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIqqiapprtLYEEPKNTFVANFIGEN 245
Cdd:COG4555  164 DVMARRLLREILRALKKE-GKTVLFSSHIMQEVEALCDRVVILHKGKV--------VAQGSLDELREEIGEEN 227
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 10-229 2.33e-53

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 176.77  E-value: 2.33e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGeNLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGM 87
Cdd:COG1120    1 MLEAENLSVGYGG-RPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRElaRRIAY 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFPHMTVAENLA---FPLT--VRGLSKTDVsERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQL 162
Cdd:COG1120   80 VPQEPPAPFGLTVRELVAlgrYPHLglFGRPSAEDR-EAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPL 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657054004 163 VLMDEPLGALDkqLReHmQME----IKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTL 229
Cdd:COG1120  159 LLLDEPTSHLD--LA-H-QLEvlelLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEV 225
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 11-220 1.74e-52

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 171.81  E-value: 1.74e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP-HKRDIGMVF 89
Cdd:cd03230    1 IEVRNLSKRY-GKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEeVKRRIGYLP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 QNYALFPHMTVAENLafpltvrglsktdvservkrvlsmvqldafaqrypaQLSGGQQQRVALARALVFEPQLVLMDEPL 169
Cdd:cd03230   80 EEPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHDPELLILDEPT 123

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 657054004 170 GALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03230  124 SGLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 13-232 4.61e-51

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 170.44  E-value: 4.61e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  13 FRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK-----RDIGM 87
Cdd:cd03256    3 VENLSKTYPNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKAlrqlrRQIGM 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFPHMTVAEN-----LAFPLTVRGL----SKTDVsERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVF 158
Cdd:cd03256   83 IFQQFNLIERLSVLENvlsgrLGRRSTWRSLfglfPKEEK-QRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALMQ 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 159 EPQLVLMDEPLGALDKQL-REHMQMeIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEE 232
Cdd:cd03256  162 QPKLILADEPVASLDPASsRQVMDL-LKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAELTDE 235
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
20-209 1.88e-50

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 169.50  E-value: 1.88e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  20 YDGENlIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNvPPHKRdiGMVFQNYALFPHMT 99
Cdd:PRK11248  11 YGGKP-ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEG-PGAER--GVVFQNEGLLPWRN 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 100 VAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREH 179
Cdd:PRK11248  87 VQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQ 166

                        170       180       190
                 ....*....|....*....|....*....|
gi 657054004 180 MQMEIKHLHQRLGVTVVYVTHDQGEALTMS 209
Cdd:PRK11248 167 MQTLLLKLWQETGKQVLLITHDIEEAVFMA 196
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 10-201 2.51e-50

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 167.27  E-value: 2.51e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP-HKRDIGMV 88
Cdd:COG4133    2 MLEAENLSCRR-GERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREdYRRRLAYL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQNYALFPHMTVAENLAFPLTVRGLSKTDvsERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEP 168
Cdd:COG4133   81 GHADGLKPELTVRENLRFWAALYGLRADR--EAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEP 158

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 657054004 169 LGALDKQ----LREHMQmeiKHLHQrlGVTVVYVTHD 201
Cdd:COG4133  159 FTALDAAgvalLAELIA---AHLAR--GGAVLLTTHQ 190
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 15-212 2.80e-50

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 167.41  E-value: 2.80e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   15 GVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRS---INNVPPHK--RD-IGMV 88
Cdd:TIGR03608   3 NISKKF-GDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQEtppLNSKKASKfrREkLGYL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   89 FQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEP 168
Cdd:TIGR03608  82 FQNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADEP 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 657054004  169 LGALDKQLReHMQMEI-KHLHQRlGVTVVYVTHDQgEALTMSDRV 212
Cdd:TIGR03608 162 TGSLDPKNR-DEVLDLlLELNDE-GKTIIIVTHDP-EVAKQADRV 203
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
14-234 3.24e-50

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 168.83  E-value: 3.24e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSI--------NNVPPHKRDI 85
Cdd:COG4598   12 RDLHKSF-GDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIrlkpdrdgELVPADRRQL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 -------GMVFQNYALFPHMTVAENLAF-PLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALV 157
Cdd:COG4598   91 qrirtrlGMVFQSFNLWSHMTVLENVIEaPVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAAIARALA 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 158 FEPQLVLMDEPLGALDKQLrehmQMEIKHLHQRL---GVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPK 234
Cdd:COG4598  171 MEPEVMLFDEPTSALDPEL----VGEVLKVMRDLaeeGRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGNPK 246
ectoine_ehuA TIGR03005
ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ...
 11-242 5.25e-50

ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding protein of a conserved four gene ABC transporter operon found next to ectoine unilization operons and ectoine biosynthesis operons. Ectoine is a compatible solute that protects enzymes from high osmolarity. It is released by some species in response to hypoosmotic shock, and it is taken up by a number of bacteria as a compatible solute or for consumption. This family shows strong sequence similiarity to a number of amino acid ABC transporter ATP-binding proteins.


Pssm-ID: 132050 [Multi-domain]  Cd Length: 252  Bit Score: 168.08  E-value: 5.25e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   11 VSFRGVQKSYdgENLIVKD-LNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK------- 82
Cdd:TIGR03005   1 VRFSDVTKRF--GILTVLDgLNFSVAAGEKVALIGPSGSGKSTILRILMTLEPIDEGQIQVEGEQLYHMPGRNgplvpad 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   83 --------RDIGMVFQNYALFPHMTVAENLAF-PLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALA 153
Cdd:TIGR03005  79 ekhlrqmrNKIGMVFQSFNLFPHKTVLDNVTEaPVLVLGMARAEAEKRAMELLDMVGLADKADHMPAQLSGGQQQRVAIA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  154 RALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEP 233
Cdd:TIGR03005 159 RALAMRPKVMLFDEVTSALDPELVGEVLNVIRRLASEHDLTMLLVTHEMGFAREFADRVCFFDKGRIVEQGKPDEIFRQP 238


                  ....*....
gi 657054004  234 KNTFVANFI 242
Cdd:TIGR03005 239 KEERTREFL 247
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 11-231 6.45e-50

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 178.10  E-value: 6.45e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDG-ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGM 87
Cdd:COG2274  474 IELENVSFRYPGdSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASlrRQIGV 553

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFpHMTVAENLAfpltvrgLSKTDVS-ERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARA 155
Cdd:COG2274  554 VLQDVFLF-SGTIRENIT-------LGDPDATdEEIIEAARLAGLHDFIEALPmgydtvvgeggSNLSGGQRQRLAIARA 625

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 156 LVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQrlGVTVVYVTHDQgEALTMSDRVAVFHQGEIQQIAPPRTLYE 231
Cdd:COG2274  626 LLRNPRILILDEATSALDAETEAIILENLRRLLK--GRTVIIIAHRL-STIRLADRIIVLDKGRIVEDGTHEELLA 698
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 6-229 7.26e-50

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 167.57  E-value: 7.26e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   6 SNDVLVSFRGVQKSYDGEnLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVpphKRDI 85
Cdd:COG1121    2 MMMPAIELENLTVSYGGR-PVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRA---RRRI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 GMVFQNYALfphmtvaeNLAFPLTV---------------RGLSKTDvSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRV 150
Cdd:COG1121   78 GYVPQRAEV--------DWDFPITVrdvvlmgrygrrglfRRPSRAD-REAVDEALERVGLEDLADRPIGELSGGQQQRV 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 151 ALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVA-----VFHQGEIQQIAP 225
Cdd:COG1121  149 LLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDRVLllnrgLVAHGPPEEVLT 227


                 ....
gi 657054004 226 PRTL 229
Cdd:COG1121  228 PENL 231
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 29-220 2.01e-49

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 165.36  E-value: 2.01e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  29 DLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQNYALFPHMTVAENLAFPL 108
Cdd:cd03298   16 HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADRPVSMLFQENNLFAHLTVEQNVGLGL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 109 tVRGLSKTDVS-ERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHL 187
Cdd:cd03298   96 -SPGLKLTAEDrQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLDL 174

                        170       180       190
                 ....*....|....*....|....*....|...
gi 657054004 188 HQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03298  175 HAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRI 207
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 27-168 5.13e-49

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 162.05  E-value: 5.13e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN--NVPPHKRDIGMVFQNYALFPHMTVAENL 104
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTddERKSLRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004  105 AFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQR----YPAQLSGGQQQRVALARALVFEPQLVLMDEP 168
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRpvgeRPGTLSGGQRQRVAIARALLTKPKLLLLDEP 148
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 5-232 7.90e-49

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 173.02  E-value: 7.90e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   5 DSNDVLVSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--K 82
Cdd:COG4988  331 AAGPPSIELEDVSFSYPGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPAswR 410

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  83 RDIGMVFQNYALFpHMTVAENLAfpltvrgLSKTDVS-ERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRV 150
Cdd:COG4988  411 RQIAWVPQNPYLF-AGTIRENLR-------LGRPDASdEELEAALEAAGLDEFVAALPdgldtplgeggRGLSGGQAQRL 482

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 151 ALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQrlGVTVVYVTHDQgEALTMSDRVAVFHQGEIQQIAPPRTLY 230
Cdd:COG4988  483 ALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAK--GRTVILITHRL-ALLAQADRILVLDDGRIVEQGTHEELL 559


                 ..
gi 657054004 231 EE 232
Cdd:COG4988  560 AK 561
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 10-232 8.17e-49

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 164.78  E-value: 8.17e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   10 LVSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK-----RD 84
Cdd:TIGR02315   1 MLEVENLSKVYPNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKlrklrRR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   85 IGMVFQNYALFPHMTVAEN-----LAFPLTVRGL----SKTDvSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARA 155
Cdd:TIGR02315  81 IGMIFQHYNLIERLTVLENvlhgrLGYKPTWRSLlgrfSEED-KERALSALERVGLADKAYQRADQLSGGQQQRVAIARA 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 657054004  156 LVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEE 232
Cdd:TIGR02315 160 LAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSELDDE 236
3a0107s01c2 TIGR00972
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ...
 20-242 1.33e-48

phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]


Pssm-ID: 273372 [Multi-domain]  Cd Length: 247  Bit Score: 164.39  E-value: 1.33e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   20 YDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSL-----MMLAGFETPTAGEILLAGRSIN----NVPPHKRDIGMVFQ 90
Cdd:TIGR00972  10 FYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLrslnrMNDLVPGVRIEGKVLFDGQDIYdkkiDVVELRRRVGMVFQ 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   91 NYALFPhMTVAENLAFPLTVRGL-SKTDVSERVKRVLSMVQL-DAFAQR---YPAQLSGGQQQRVALARALVFEPQLVLM 165
Cdd:TIGR00972  90 KPNPFP-MSIYDNIAYGPRLHGIkDKKELDEIVEESLKKAALwDEVKDRlhdSALGLSGGQQQRLCIARALAVEPEVLLL 168

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004  166 DEPLGALDKQlrehMQMEIKHLHQRL--GVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFI 242
Cdd:TIGR00972 169 DEPTSALDPI----ATGKIEELIQELkkKYTIVIVTHNMQQAARISDRTAFFYDGELVEYGPTEQIFTNPKEKRTEDYI 243
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 31-223 2.38e-48

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 162.72  E-value: 2.38e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   31 NLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQNYALFPHMTVAENLAFPLTv 110
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLAPYQRPVSMLFQENNLFAHLTVRQNIGLGLH- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  111 RGLSKTDVS-ERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQ 189
Cdd:TIGR01277  97 PGLKLNAEQqEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQLCS 176

                         170       180       190
                  ....*....|....*....|....*....|....
gi 657054004  190 RLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQI 223
Cdd:TIGR01277 177 ERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVV 210
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 14-220 4.75e-48

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 162.22  E-value: 4.75e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKR---DIGMVFQ 90
Cdd:cd03224    4 ENLNAGY-GKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERaraGIGYVPE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAfpLTVRGLSKTDVSERVKRVLSMV-QLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPL 169
Cdd:cd03224   83 GRRIFPELTVEENLL--LGAYARRRAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPS 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 657054004 170 GALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03224  161 EGLAPKIVEEIFEAIRELRDE-GVTILLVEQNARFALEIADRAYVLERGRV 210
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
22-241 7.84e-48

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 166.75  E-value: 7.84e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP------HKRDIGMVFQNYALF 95
Cdd:PRK10070  39 GLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDaelrevRRKKIAMVFQSFALM 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  96 PHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQ 175
Cdd:PRK10070 119 PHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPL 198

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 176 LREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANF 241
Cdd:PRK10070 199 IRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTF 264
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 7-234 1.65e-47

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 168.71  E-value: 1.65e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   7 NDVLVSF---RGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFEtPTAGEILLAGRSINNVP---- 79
Cdd:COG4172  279 RDLKVWFpikRGLFRRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFDGQDLDGLSrral 357

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  80 -PHKRDIGMVFQN-YA-LFPHMTVAENLAFPLTV--RGLSKTDVSERVKRVLSMVQLD-AFAQRYPAQLSGGQQQRVALA 153
Cdd:COG4172  358 rPLRRRMQVVFQDpFGsLSPRMTVGQIIAEGLRVhgPGLSAAERRARVAEALEEVGLDpAARHRYPHEFSGGQRQRIAIA 437

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 154 RALVFEPQLVLMDEPLGALDKQLrehmQMEI----KHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTL 229
Cdd:COG4172  438 RALILEPKLLVLDEPTSALDVSV----QAQIldllRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQV 513


                 ....*
gi 657054004 230 YEEPK 234
Cdd:COG4172  514 FDAPQ 518
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-242 3.90e-47

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 160.97  E-value: 3.90e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   1 MSEVDSN-DVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSL-----M--MLAGFETptAGEILLAG 72
Cdd:COG1117    1 MTAPASTlEPKIEVRNLNVYY-GDKQALKDINLDIPENKVTALIGPSGCGKSTLLrclnrMndLIPGARV--EGEILLDG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  73 RSIN----NVPPHKRDIGMVFQNYALFPhMTVAENLAFPLTVRGL-SKTDVSERVKRVLSMV--------QLDAFAQRyp 139
Cdd:COG1117   78 EDIYdpdvDVVELRRRVGMVFQKPNPFP-KSIYDNVAYGLRLHGIkSKSELDEIVEESLRKAalwdevkdRLKKSALG-- 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 140 aqLSGGQQQRVALARALVFEPQLVLMDEPLGALD-----------KQLREHMqmeikhlhqrlgvTVVYVTHDQGEALTM 208
Cdd:COG1117  155 --LSGGQQQRLCIARALAVEPEVLLMDEPTSALDpistakieeliLELKKDY-------------TIVIVTHNMQQAARV 219

                        250       260       270
                 ....*....|....*....|....*....|....
gi 657054004 209 SDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFI 242
Cdd:COG1117  220 SDYTAFFYLGELVEFGPTEQIFTNPKDKRTEDYI 253
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 14-243 7.74e-47

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 159.92  E-value: 7.74e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYDGENlIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILL------AGRSINN----VPPHKR 83
Cdd:PRK11264   7 KNLVKKFHGQT-VLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVgditidTARSLSQqkglIRQLRQ 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  84 DIGMVFQNYALFPHMTVAEN-LAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQL 162
Cdd:PRK11264  86 HVGFVFQNFNLFPHRTVLENiIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEV 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 163 VLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKN----TFV 238
Cdd:PRK11264 166 ILFDEPTSALDPELVGEVLNTIRQLAQE-KRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQprtrQFL 244


                 ....*
gi 657054004 239 ANFIG 243
Cdd:PRK11264 245 EKFLL 249
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 11-219 3.95e-46

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 155.23  E-value: 3.95e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDG-ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGM 87
Cdd:cd03228    1 IEFKNVSFSYPGrPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESlrKNIAY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFpHMTVAENLafpltvrglsktdvservkrvlsmvqldafaqrypaqLSGGQQQRVALARALVFEPQLVLMDE 167
Cdd:cd03228   81 VPQDPFLF-SGTIRENI-------------------------------------LSGGQRQRIAIARALLRDPPILILDE 122

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 657054004 168 PLGALDKQLREHMQMEIKHLHQrlGVTVVYVTHDQgEALTMSDRVAVFHQGE 219
Cdd:cd03228  123 ATSALDPETEALILEALRALAK--GKTVIVIAHRL-STIRDADRIIVLDDGR 171
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 13-220 4.24e-46

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 160.74  E-value: 4.24e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  13 FRGVQKSYDGENLIV---KDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH-----KRD 84
Cdd:PRK11153   4 LKNISKVFPQGGRTIhalNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKelrkaRRQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 IGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVL 164
Cdd:PRK11153  84 IGMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVLL 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 657054004 165 MDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDqgealtMS------DRVAVFHQGEI 220
Cdd:PRK11153 164 CDEATSALDPATTRSILELLKDINRELGLTIVLITHE------MDvvkricDRVAVIDAGRL 219
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 19-215 7.12e-46

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 156.15  E-value: 7.12e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  19 SYDGENlIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPphkRDIGMVFQNYALfphm 98
Cdd:cd03235    8 SYGGHP-VLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKER---KRIGYVPQRRSI---- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 tvaeNLAFPLTVR---------------GLSKTDvSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLV 163
Cdd:cd03235   80 ----DRDFPISVRdvvlmglyghkglfrRLSKAD-KAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLL 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 657054004 164 LMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVF 215
Cdd:cd03235  155 LLDEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLL 205
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 18-220 7.98e-46

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 156.38  E-value: 7.98e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  18 KSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH-KRDIGMVFQNYALFP 96
Cdd:cd03265    8 KKY-GDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREvRRRIGIVFQDLSVDD 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  97 HMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQL 176
Cdd:cd03265   87 ELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDPQT 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 657054004 177 REHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03265  167 RAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRI 210
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 12-219 1.67e-45

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 153.17  E-value: 1.67e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  12 SFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGMVF 89
Cdd:cd00267    1 EIENLSFRY-GGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEelRRRIGYVP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 QnyalfphmtvaenlafpltvrglsktdvservkrvlsmvqldafaqrypaqLSGGQQQRVALARALVFEPQLVLMDEPL 169
Cdd:cd00267   80 Q---------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPT 108

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 657054004 170 GALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGE 219
Cdd:cd00267  109 SGLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 14-220 1.92e-45

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 153.75  E-value: 1.92e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRdigmvfqnya 93
Cdd:cd03214    3 ENLSVGY-GGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKEL---------- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  94 lfphmtvAENLAFpltvrglsktdvserVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALD 173
Cdd:cd03214   72 -------ARKIAY---------------VPQALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLD 129

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 657054004 174 KqlreHMQME----IKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03214  130 I----AHQIEllelLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRI 176
cbiO PRK13650
energy-coupling factor transporter ATPase;
21-230 3.52e-45

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 156.43  E-value: 3.52e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  21 DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGR--SINNVPPHKRDIGMVFQNY-ALFPH 97
Cdd:PRK13650  17 DQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDllTEENVWDIRHKIGMVFQNPdNQFVG 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  98 MTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLR 177
Cdd:PRK13650  97 ATVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGR 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 657054004 178 EHMQMEIKHLHQRLGVTVVYVTHDQGEaLTMSDRVAVFHQGEIQQIAPPRTLY 230
Cdd:PRK13650 177 LELIKTIKGIRDDYQMTVISITHDLDE-VALSDRVLVMKNGQVESTSTPRELF 228
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
31-220 4.00e-45

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 154.74  E-value: 4.00e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  31 NLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQNYALFPHMTVAENLAFPLTv 110
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLN- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 111 RGLsKTDVSER--VKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLH 188
Cdd:PRK10771  98 PGL-KLNAAQRekLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQVC 176

                        170       180       190
                 ....*....|....*....|....*....|..
gi 657054004 189 QRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:PRK10771 177 QERQLTLLMVSHSLEDAARIAPRSLVVADGRI 208
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
16-242 1.19e-44

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 154.36  E-value: 1.19e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  16 VQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVpphkRD----------- 84
Cdd:PRK10619  11 LHKRY-GEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLV----RDkdgqlkvadkn 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 --------IGMVFQNYALFPHMTVAEN-LAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQ-RYPAQLSGGQQQRVALAR 154
Cdd:PRK10619  86 qlrllrtrLTMVFQHFNLWSHMTVLENvMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQgKYPVHLSGGQQQRVSIAR 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 155 ALVFEPQLVLMDEPLGALDKQLREhmqmEIKHLHQRL---GVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYE 231
Cdd:PRK10619 166 ALAMEPEVLLFDEPTSALDPELVG----EVLRIMQQLaeeGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFG 241

                        250
                 ....*....|.
gi 657054004 232 EPKNTFVANFI 242
Cdd:PRK10619 242 NPQSPRLQQFL 252
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
10-231 1.29e-44

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 154.79  E-value: 1.29e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSY-DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGR--SINNVPPHKRDIG 86
Cdd:PRK13635   5 IIRVEHISFRYpDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMvlSEETVWDVRRQVG 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 MVFQNY-ALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLM 165
Cdd:PRK13635  85 MVFQNPdNQFVGATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIIL 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 166 DEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTmSDRVAVFHQGEIQQIAPPRTLYE 231
Cdd:PRK13635 165 DEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIFK 229
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
10-220 1.81e-44

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 152.72  E-value: 1.81e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN-----NVPPHKRD 84
Cdd:PRK10908   1 MIRFEHVSKAYLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITrlknrEVPFLRRQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 IGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVL 164
Cdd:PRK10908  81 IGMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 165 MDEPLGALDKQLREHMqMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:PRK10908 161 ADEPTGNLDDALSEGI-LRLFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGHL 215
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
27-258 5.30e-44

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 153.07  E-value: 5.30e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN--NVPPHKRDIGMVFQ--NYALFPHMTVAE 102
Cdd:COG4167   29 VKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLEygDYKYRCKHIRMIFQdpNTSLNPRLNIGQ 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 103 NLAFPLtvRGLSKTDVSERVKRV---LSMVQLDA-FAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLRE 178
Cdd:COG4167  109 ILEEPL--RLNTDLTAEEREERIfatLRLVGLLPeHANFYPHMLSSGQKQRVALARALILQPKIIIADEALAALDMSVRS 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 179 HMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVAnfigennRLngrLHSHTGE 258
Cdd:COG4167  187 QIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEVFANPQHEVTK-------RL---IESHFGE 256
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 2-233 6.18e-44

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 159.55  E-value: 6.18e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   2 SEVDSNDVLVSFRGVQKSYDGENLIV-KDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP 80
Cdd:COG4987  325 PAPAPGGPSLELEDVSFRYPGAGRPVlDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDE 404

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  81 ---HKRdIGMVFQNYALFpHMTVAENLAfpltvrgLSKTDVS-ERVKRVLSMVQLDAFAQRYP-----------AQLSGG 145
Cdd:COG4987  405 ddlRRR-IAVVPQRPHLF-DTTLRENLR-------LARPDATdEELWAALERVGLGDWLAALPdgldtwlgeggRRLSGG 475

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 146 QQQRVALARALVFEPQLVLMDEPLGALDKQLREH-MQMEIKHLHQRlgvTVVYVTHDQgEALTMSDRVAVFHQGEIQQIA 224
Cdd:COG4987  476 ERRRLALARALLRDAPILLLDEPTEGLDAATEQAlLADLLEALAGR---TVLLITHRL-AGLERMDRILVLEDGRIVEQG 551


                 ....*....
gi 657054004 225 PPRTLYEEP 233
Cdd:COG4987  552 THEELLAQN 560
cbiO PRK13637
energy-coupling factor transporter ATPase;
27-232 6.48e-44

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 153.28  E-value: 6.48e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN----NVPPHKRDIGMVFQ--NYALFPHmTV 100
Cdd:PRK13637  23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITdkkvKLSDIRKKVGLVFQypEYQLFEE-TI 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 101 AENLAFPLTVRGLSKTDVSERVKRVLSMVQLD--AFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLRE 178
Cdd:PRK13637 102 EKDIAFGPINLGLSEEEIENRVKRAMNIVGLDyeDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRD 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 657054004 179 HMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEE 232
Cdd:PRK13637 182 EILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFKE 235
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
11-220 1.87e-43

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 158.40  E-value: 1.87e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGMV 88
Cdd:COG1132  340 IEFENVSFSYPGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESlrRQIGVV 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQNYALFpHMTVAENLAFpltvrglSKTDVS-ERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARAL 156
Cdd:COG1132  420 PQDTFLF-SGTIRENIRY-------GRPDATdEEVEEAAKAAQAHEFIEALPdgydtvvgergVNLSGGQRQRIAIARAL 491

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657054004 157 VFEPQLVLMDEPLGALD----KQLREHMQmeiKHLHQRlgvTVVYVTHDqgeaLT---MSDRVAVFHQGEI 220
Cdd:COG1132  492 LKDPPILILDEATSALDteteALIQEALE---RLMKGR---TTIVIAHR----LStirNADRILVLDDGRI 552
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 14-220 2.43e-43

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 150.00  E-value: 2.43e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKR---DIGMVFQ 90
Cdd:cd03218    4 ENLSKRY-GKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRarlGIGYLPQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:cd03218   83 EASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEPFA 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 657054004 171 ALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03218  163 GVDPIAVQDIQKIIKILKDR-GIGVLITDHNVRETLSITDRAYIIYEGKV 211
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 8-220 3.76e-43

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 149.75  E-value: 3.76e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   8 DVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKR---D 84
Cdd:COG0410    1 MPMLEVENLHAGY-GGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIarlG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 IGMVFQNYALFPHMTVAENLAFPLTVRGlSKTDVSERVKRVLSMV-QLDAFAQRYPAQLSGGQQQRVALARALVFEPQLV 163
Cdd:COG0410   80 IGYVPEGRRIFPSLTVEENLLLGAYARR-DRAEVRADLERVYELFpRLKERRRQRAGTLSGGEQQMLAIGRALMSRPKLL 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 164 LMDEP-LGaLDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:COG0410  159 LLDEPsLG-LAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRAYVLERGRI 214
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
10-225 1.24e-41

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 146.76  E-value: 1.24e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGENL--------IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVP-- 79
Cdd:PRK10419   3 LLNVSGLSHHYAHGGLsgkhqhqtVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNra 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  80 ---PHKRDIGMVFQNY--ALFPHMTVAENLAFPLT-VRGLSKTDVSERVKRVLSMVQLDA-FAQRYPAQLSGGQQQRVAL 152
Cdd:PRK10419  83 qrkAFRRDIQMVFQDSisAVNPRKTVREIIREPLRhLLSLDKAERLARASEMLRAVDLDDsVLDKRPPQLSGGQLQRVCL 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 153 ARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAP 225
Cdd:PRK10419 163 ARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQP 235
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 11-234 1.67e-41

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 152.53  E-value: 1.67e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGvqksYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKT-TSLMML----AGFETPTaGEILLAGRSINNVPPHK--- 82
Cdd:COG4172   14 VAFGQ----GGGTVEAVKGVSFDIAAGETLALVGESGSGKSvTALSILrllpDPAAHPS-GSILFDGQDLLGLSERElrr 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  83 ---RDIGMVFQN--YALFPHMTVAENLAFPLTV-RGLSKTDVSERVKRVLSMVQLDAFAQR---YPAQLSGGQQQRVALA 153
Cdd:COG4172   89 irgNRIAMIFQEpmTSLNPLHTIGKQIAEVLRLhRGLSGAAARARALELLERVGIPDPERRldaYPHQLSGGQRQRVMIA 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 154 RALVFEPQLVLMDEPLGALDKQLrehmQMEI----KHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTL 229
Cdd:COG4172  169 MALANEPDLLIADEPTTALDVTV----QAQIldllKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAEL 244


                 ....*
gi 657054004 230 YEEPK 234
Cdd:COG4172  245 FAAPQ 249
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 11-220 2.00e-41

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 144.28  E-value: 2.00e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQ 90
Cdd:cd03268    1 LKTNDLTKTY-GKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEALRRIGALIE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAFPLTVRGLSKtdvsERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:cd03268   80 APGFYPNLTARENLRLLARLLGIRK----KRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTN 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 657054004 171 ALD----KQLRehmqmEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03268  156 GLDpdgiKELR-----ELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKL 204
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
29-220 2.20e-41

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 148.48  E-value: 2.20e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  29 DLNLDIRkgefLTL--------LGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN------NVPPHKRDIGMVFQNYAL 94
Cdd:PRK11144  12 DLCLTVN----LTLpaqgitaiFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFdaekgiCLPPEKRRIGYVFQDARL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  95 FPHMTVAENLAFpltvrGLSKTDVSErVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALD- 173
Cdd:PRK11144  88 FPHYKVRGNLRY-----GMAKSMVAQ-FDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDl 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 657054004 174 --KqlREHMQMeIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:PRK11144 162 prK--RELLPY-LERLAREINIPILYVSHSLDEILRLADRVVVLEQGKV 207
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 11-296 4.63e-41

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 146.02  E-value: 4.63e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINnvPPHKRDIGmvfq 90
Cdd:COG4152    2 LELKGLTKRF-GDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLD--PEDRRRIG---- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 nY-----ALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLM 165
Cdd:COG4152   75 -YlpeerGLYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLIL 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 166 DEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQG---------EIQQIAPPRTLYEEPKNT 236
Cdd:COG4152  154 DEPFSGLDPVNVELLKDVIRELAAK-GTTVIFSSHQMELVEELCDRIVIINKGrkvlsgsvdEIRRQFGRNTLRLEADGD 232

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657054004 237 FvanfiGENNRLNG-RLHSHTGERCVVELARGEKVEALAVNVGQIGGPVTLSvrPERVSLN 296
Cdd:COG4152  233 A-----GWLRALPGvTVVEEDGDGAELKLEDGADAQELLRALLARGPVREFE--EVRPSLN 286
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 11-220 5.05e-41

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 143.58  E-value: 5.05e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINnvPPHKRDIGMVFQ 90
Cdd:cd03269    1 LEVENVTKRF-GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLD--IAARNRIGYLPE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:cd03269   78 ERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFS 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 657054004 171 ALDKQLREHMQMEIKHLhQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03269  158 GLDPVNVELLKDVIREL-ARAGKTVILSTHQMELVEELCDRVLLLNKGRA 206
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
6-222 4.99e-40

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 141.49  E-value: 4.99e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   6 SNDVLVSFRGVQKSYDGENL---IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP-- 80
Cdd:PRK11629   1 MNKILLQCDNLCKRYQEGSVqtdVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSaa 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  81 ----HKRDIGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARAL 156
Cdd:PRK11629  81 kaelRNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARAL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 157 VFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVfHQGEIQQ 222
Cdd:PRK11629 161 VNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEM-RDGRLTA 225
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
7-220 5.42e-40

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 147.86  E-value: 5.42e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   7 NDVLVSFRGVQKSYDGeNLIVKDLNLDIRKGEFLTLLGPSGSGKTTsLM-MLAGFETPTAGEILLAGRSINNVPPH---K 82
Cdd:COG1129    1 AEPLLEMRGISKSFGG-VKALDGVSLELRPGEVHALLGENGAGKST-LMkILSGVYQPDSGEILLDGEPVRFRSPRdaqA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  83 RDIGMVFQNYALFPHMTVAENLAF---PLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFE 159
Cdd:COG1129   79 AGIAIIHQELNLVPNLSVAENIFLgrePRRGGLIDWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRD 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 657054004 160 PQLVLMDEPLGALDKQlrehmqmEIKHLHQRL------GVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:COG1129  159 ARVLILDEPTASLTER-------EVERLFRIIrrlkaqGVAIIYISHRLDEVFEIADRVTVLRDGRL 218
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 14-234 7.11e-40

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 141.32  E-value: 7.11e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKR---DIGMVFQ 90
Cdd:COG1137    7 ENLVKSY-GKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHKRarlGIGYLPQ 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:COG1137   86 EASIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFILLDEPFA 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 171 ALD-------KQLrehmqmeIKHLHQR-LGvtvVYVT-HDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPK 234
Cdd:COG1137  166 GVDpiavadiQKI-------IRHLKERgIG---VLITdHNVRETLGICDRAYIISEGKVLAEGTPEEILNNPL 228
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
 14-248 2.40e-39

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 139.72  E-value: 2.40e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   14 RGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKR---DIGMVFQ 90
Cdd:TIGR04406   5 ENLIKSY-KKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDITHLPMHERarlGIGYLPQ 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   91 NYALFPHMTVAENLAFPLTVRG-LSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPL 169
Cdd:TIGR04406  84 EASIFRKLTVEENIMAVLEIRKdLDRAEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKFILLDEPF 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004  170 GALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVanFIGENNRL 248
Cdd:TIGR04406 164 AGVDPIAVGDIKKIIKHLKER-GIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPAEIVANEKVRRV--YLGEQFRL 239
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 10-220 2.83e-39

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 139.04  E-value: 2.83e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYD---GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH-KRDI 85
Cdd:cd03266    1 MITADALTKRFRdvkKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAEaRRRL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 GMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLM 165
Cdd:cd03266   81 GFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLL 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 166 DEPLGALDKQLREHMQMEIKHLhQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03266  161 DEPTTGLDVMATRALREFIRQL-RALGKCILFSTHIMQEVERLCDRVVVLHRGRV 214
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
11-232 2.99e-39

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 141.48  E-value: 2.99e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRD-IGMVF 89
Cdd:PRK13537   8 IDFRNVEKRY-GDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQrVGVVP 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 QNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPL 169
Cdd:PRK13537  87 QFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPT 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 657054004 170 GALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQG-EIQQIAPPRTLYEE 232
Cdd:PRK13537 167 TGLDPQARHLMWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVIEEGrKIAEGAPHALIESE 229
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
22-228 5.23e-39

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 139.48  E-value: 5.23e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGMVFQNYAL-FPhM 98
Cdd:COG4559   12 GGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWElaRRRAVLPQHSSLaFP-F 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 TVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALV-------FEPQLVLMDEPLGA 171
Cdd:COG4559   91 TVEEVVALGRAPHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAqlwepvdGGPRWLFLDEPTSA 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 172 LDkqlrehmqmeIKHLHQ---------RLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRT 228
Cdd:COG4559  171 LD----------LAHQHAvlrlarqlaRRGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEE 226
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 20-242 7.79e-39

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 139.21  E-value: 7.79e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  20 YDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTslmMLAGF--------ETPTAGEILLAGRSINN--VPP--HKRDIGM 87
Cdd:PRK14267  13 YYGSNHVIKGVDLKIPQNGVFALMGPSGCGKST---LLRTFnrllelneEARVEGEVRLFGRNIYSpdVDPieVRREVGM 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFPHMTVAENLAFPLTVRGL--SKTDVSERVKRVLSMVQL-DAFAQR---YPAQLSGGQQQRVALARALVFEPQ 161
Cdd:PRK14267  90 VFQYPNPFPHLTIYDNVAIGVKLNGLvkSKKELDERVEWALKKAALwDEVKDRlndYPSNLSGGQRQRLVIARALAMKPK 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 162 LVLMDEPLGALD---KQLREHMQMEIKHLHqrlgvTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFV 238
Cdd:PRK14267 170 ILLMDEPTANIDpvgTAKIEELLFELKKEY-----TIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENPEHELT 244


                 ....
gi 657054004 239 ANFI 242
Cdd:PRK14267 245 EKYV 248
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 11-220 1.50e-38

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 137.34  E-value: 1.50e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDG-ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGM 87
Cdd:cd03245    3 IEFRNVSFSYPNqEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPAdlRRNIGY 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFpHMTVAENlafpLTVRGLSKTDvsERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARAL 156
Cdd:cd03245   83 VPQDVTLF-YGTLRDN----ITLGAPLADD--ERILRAAELAGVTDFVNKHPngldlqigergRGLSGGQRQAVALARAL 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 157 VFEPQLVLMDEPLGALDKQLrehmQMEIKHLHQRL--GVTVVYVTHDQgEALTMSDRVAVFHQGEI 220
Cdd:cd03245  156 LNDPPILLLDEPTSAMDMNS----EERLKERLRQLlgDKTLIIITHRP-SLLDLVDRIIVMDSGRI 216
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 22-228 2.19e-38

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 137.98  E-value: 2.19e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGMVFQNYAL-FPhM 98
Cdd:PRK13548  13 GGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAElaRRRAVLPQHSSLsFP-F 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 TVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALV------FEPQLVLMDEPLGAL 172
Cdd:PRK13548  92 TVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdGPPRWLLLDEPTSAL 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004 173 DkqLReHMQ--MEI-KHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRT 228
Cdd:PRK13548 172 D--LA-HQHhvLRLaRQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAE 227
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 23-233 3.87e-38

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 138.23  E-value: 3.87e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  23 ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN------NVPPHKRDIGMVFQnyalFP 96
Cdd:PRK13634  19 ERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITagkknkKLKPLRKKVGIVFQ----FP 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  97 -HM----TVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLD-AFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:PRK13634  95 eHQlfeeTVEKDICFGPMNFGVSEEDAKQKAREMIELVGLPeELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTA 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 657054004 171 ALDKQLR-EHMQMeIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEP 233
Cdd:PRK13634 175 GLDPKGRkEMMEM-FYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADP 237
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 5-226 4.80e-38

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 137.43  E-value: 4.80e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   5 DSNDVLVSFRGVQKSYDG-ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN--NVPPH 81
Cdd:PRK13632   2 KNKSVMIKVENVSFSYPNsENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISkeNLKEI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  82 KRDIGMVFQNY-ALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEP 160
Cdd:PRK13632  82 RKKIGIIFQNPdNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNP 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 161 QLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALtMSDRVAVFHQGEIQQIAPP 226
Cdd:PRK13632 162 EIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKLIAQGKP 226
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
10-227 6.56e-38

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 143.71  E-value: 6.56e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSY---DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP------ 80
Cdd:PRK10535   4 LLELKDIRRSYpsgEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDAdalaql 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  81 HKRDIGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEP 160
Cdd:PRK10535  84 RREHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGG 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 657054004 161 QLVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEAlTMSDRVAVFHQGEIQQIAPPR 227
Cdd:PRK10535 164 QVILADEPTGALDSHSGEEVMAILHQLRDR-GHTVIIVTHDPQVA-AQAERVIEIRDGEIVRNPPAQ 228
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 15-222 2.23e-37

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 133.86  E-value: 2.23e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  15 GVQKSYDGEnLIVKDLNLDIRKGeFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRD-IGMVFQNYA 93
Cdd:cd03264    5 NLTKRYGKK-RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRrIGYLPQEFG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  94 LFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALD 173
Cdd:cd03264   83 VYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLD 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 657054004 174 KQLRehmqMEIKHLHQRLG--VTVVYVTHDQGEALTMSDRVAVFHQGEIQQ 222
Cdd:cd03264  163 PEER----IRFRNLLSELGedRIVILSTHIVEDVESLCNQVAVLNKGKLVF 209
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 1-242 2.66e-37

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 135.04  E-value: 2.66e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   1 MSEVDSNDVLVSFRGVQksydgenlIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGF-----ETPTAGEILLAGRSI 75
Cdd:PRK14247   1 MNKIEIRDLKVSFGQVE--------VLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDI 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  76 NNVP--PHKRDIGMVFQNYALFPHMTVAENLAFPLTVRGL--SKTDVSERVKRVLSMVQL-DAFAQRYPA---QLSGGQQ 147
Cdd:PRK14247  73 FKMDviELRRRVQMVFQIPNPIPNLSIFENVALGLKLNRLvkSKKELQERVRWALEKAQLwDEVKDRLDApagKLSGGQQ 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 148 QRVALARALVFEPQLVLMDEPLGALDKQlrEHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPR 227
Cdd:PRK14247 153 QRLCIARALAFQPEVLLADEPTANLDPE--NTAKIESLFLELKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTR 230

                        250
                 ....*....|....*
gi 657054004 228 TLYEEPKNTFVANFI 242
Cdd:PRK14247 231 EVFTNPRHELTEKYV 245
cbiO PRK13640
energy-coupling factor transporter ATPase;
6-233 3.26e-37

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 135.70  E-value: 3.26e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   6 SNDVLVSFRGVQKSY-DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGE---ILLAGRSIN--NVP 79
Cdd:PRK13640   1 MKDNIVEFKHVSFTYpDSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPnskITVDGITLTakTVW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  80 PHKRDIGMVFQNY-ALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVF 158
Cdd:PRK13640  81 DIREKVGIVFQNPdNQFVGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAV 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 159 EPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEAlTMSDRVAVFHQGEIQQIAPPRTLYEEP 233
Cdd:PRK13640 161 EPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEIFSKV 234
nickel_nikD TIGR02770
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...
 26-236 6.27e-37

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131817 [Multi-domain]  Cd Length: 230  Bit Score: 133.26  E-value: 6.27e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETP----TAGEILLAGRSINNVPPHKRDIGMVFQN--YALFPHMT 99
Cdd:TIGR02770   1 LVQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPgltqTSGEILLDGRPLLPLSIRGRHIATIMQNprTAFNPLFT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  100 VAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQ---RYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQL 176
Cdd:TIGR02770  81 MGNHAIETLRSLGKLSKQARALILEALEAVGLPDPEEvlkKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDLDVVN 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  177 REHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNT 236
Cdd:TIGR02770 161 QARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHE 220
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 6-214 1.12e-36

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 138.62  E-value: 1.12e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   6 SNDVLVSFRGVQKSYDGenlIV--KDLNLDIRKGEFLTLLGPSGSGKTTsLM-MLAGFETPTAGEILLAGR--SINNvpP 80
Cdd:COG3845    1 MMPPALELRGITKRFGG---VVanDDVSLTVRPGEIHALLGENGAGKST-LMkILYGLYQPDSGEILIDGKpvRIRS--P 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  81 H---KRDIGMVFQNYALFPHMTVAENLAF---PLTVRGLSKTDVSERVKrvlsmvqldAFAQRYP---------AQLSGG 145
Cdd:COG3845   75 RdaiALGIGMVHQHFMLVPNLTVAENIVLglePTKGGRLDRKAARARIR---------ELSERYGldvdpdakvEDLSVG 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 146 QQQRVALARALVFEPQLVLMDEPLGALDKQlrehmqmEIKHLHQRL------GVTVVYVTHDQGEALTMSDRVAV 214
Cdd:COG3845  146 EQQRVEILKALYRGARILILDEPTAVLTPQ-------EADELFEILrrlaaeGKSIIFITHKLREVMAIADRVTV 213
cbiO PRK13644
energy-coupling factor transporter ATPase;
10-233 1.65e-36

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 133.57  E-value: 1.65e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRS---INNVPPHKRDIG 86
Cdd:PRK13644   1 MIRLENVSYSYPDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDtgdFSKLQGIRKLVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 MVFQN-YALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLM 165
Cdd:PRK13644  81 IVFQNpETQFVGRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIF 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 166 DEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQgEALTMSDRVAVFHQGEIQQIAPPRTLYEEP 233
Cdd:PRK13644 161 DEVTSMLDPDSGIAVLERIKKLHEK-GKTIVYITHNL-EELHDADRIIVMDRGKIVLEGEPENVLSDV 226
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 11-237 2.30e-36

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 138.30  E-value: 2.30e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSF---RGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFeTPTAGEILLAGRSINNVP-----PHK 82
Cdd:PRK15134 283 VAFpirKGILKRTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRL-INSQGEIWFDGQPLHNLNrrqllPVR 361

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  83 RDIGMVFQ--NYALFPHMTVAENLAFPLTV--RGLSKTDVSERVKRVLSMVQLDAFA-QRYPAQLSGGQQQRVALARALV 157
Cdd:PRK15134 362 HRIQVVFQdpNSSLNPRLNVLQIIEEGLRVhqPTLSAAQREQQVIAVMEEVGLDPETrHRYPAEFSGGQRQRIAIARALI 441

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 158 FEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTF 237
Cdd:PRK15134 442 LKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEY 521
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 23-220 3.61e-36

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 132.13  E-value: 3.61e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  23 ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKR--DIGMVFQNYAL--FPHM 98
Cdd:COG1101   18 EKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRakYIGRVFQDPMMgtAPSM 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 TVAENLA--------FPLTvRGLSKTDvSERVKRVLSMV------QLDAFAqrypAQLSGGQQQRVALARALVFEPQLVL 164
Cdd:COG1101   98 TIEENLAlayrrgkrRGLR-RGLTKKR-RELFRELLATLglglenRLDTKV----GLLSGGQRQALSLLMATLTKPKLLL 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 657054004 165 MDEPLGALDKQlREHMQMEI-KHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:COG1101  172 LDEHTAALDPK-TAALVLELtEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGRI 227
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 11-232 4.87e-36

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 131.12  E-value: 4.87e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDG--ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIG 86
Cdd:cd03249    1 IEFKNVSFRYPSrpDVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRwlRSQIG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 MVFQNYALFPhMTVAENLAFpltvrGLSKTDVSErVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARA 155
Cdd:cd03249   81 LVSQEPVLFD-GTIAENIRY-----GKPDATDEE-VEEAAKKANIHDFIMSLPdgydtlvgergSQLSGGQKQRIAIARA 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 657054004 156 LVFEPQLVLMDEPLGALDKQLREHMQMEIKHLhqRLGVTVVYVTHdQGEALTMSDRVAVFHQGEIQQIAPPRTLYEE 232
Cdd:cd03249  154 LLRNPKILLLDEATSALDAESEKLVQEALDRA--MKGRTTIVIAH-RLSTIRNADLIAVLQNGQVVEQGTHDELMAQ 227
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
10-210 1.03e-35

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 131.04  E-value: 1.03e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSyDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGrsiNNVPPHKRD----- 84
Cdd:PRK11831   7 LVDMRGVSFT-RGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDG---ENIPAMSRSrlytv 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 ---IGMVFQNYALFPHMTVAENLAFPLTvrglSKTDVSERVKRVLSMVQLDAF-----AQRYPAQLSGGQQQRVALARAL 156
Cdd:PRK11831  83 rkrMSMLFQSGALFTDMNVFDNVAYPLR----EHTQLPAPLLHSTVMMKLEAVglrgaAKLMPSELSGGMARRAALARAI 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 657054004 157 VFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSD 210
Cdd:PRK11831 159 ALEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIAD 212
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 25-218 1.38e-35

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 130.50  E-value: 1.38e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  25 LIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK-RDIGMV--FQNYALFPHMTVA 101
Cdd:PRK11300  19 LAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQiARMGVVrtFQHVRLFREMTVI 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 102 ENL--AFPLTVR-----GLSKT--------DVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMD 166
Cdd:PRK11300  99 ENLlvAQHQQLKtglfsGLLKTpafrraesEALDRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLD 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 657054004 167 EPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQG 218
Cdd:PRK11300 179 EPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQG 230
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 27-280 1.57e-35

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 131.75  E-value: 1.57e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEI--------------------------LLAGRSINNVPP 80
Cdd:PRK13651  23 LDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewifkdeknkkktkekekvleklviqKTRFKKIKKIKE 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  81 HKRDIGMVFQ--NYALFpHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLD-AFAQRYPAQLSGGQQQRVALARALV 157
Cdd:PRK13651 103 IRRRVGVVFQfaEYQLF-EQTIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGLDeSYLQRSPFELSGGQKRRVALAGILA 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 158 FEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIqqIAPPRTlYEEPKNTf 237
Cdd:PRK13651 182 MEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDLDNVLEWTKRTIFFKDGKI--IKDGDT-YDILSDN- 256

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 657054004 238 vaNFIGENNRLNGRLhshtgercvveLARGEKVEALAVNVGQI 280
Cdd:PRK13651 257 --KFLIENNMEPPKL-----------LNFVNKLEKKGIDVPKV 286
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 5-231 1.76e-35

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 130.64  E-value: 1.76e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   5 DSNDVLVSFRGVQKSYDG-ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN--NVPPH 81
Cdd:PRK13648   2 EDKNSIIVFKNVSFQYQSdASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITddNFEKL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  82 KRDIGMVFQN-YALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEP 160
Cdd:PRK13648  82 RKHIGIVFQNpDNQFVGSIVKYDVAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNP 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657054004 161 QLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTmSDRVAVFHQGEIQQIAPPRTLYE 231
Cdd:PRK13648 162 SVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFD 231
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 11-220 2.01e-35

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 136.92  E-value: 2.01e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   11 VSFRGVQKSYDG-ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGM 87
Cdd:TIGR03375 464 IEFRNVSFAYPGqETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPAdlRRNIGY 543

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   88 VFQNYALFpHMTVAENLAFpltvRGLSKTDvsERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARAL 156
Cdd:TIGR03375 544 VPQDPRLF-YGTLRDNIAL----GAPYADD--EEILRAAELAGVTEFVRRHPdgldmqigergRSLSGGQRQAVALARAL 616

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004  157 VFEPQLVLMDEPLGALDKQLREHMqmeIKHLHQRL-GVTVVYVTHdQGEALTMSDRVAVFHQGEI 220
Cdd:TIGR03375 617 LRDPPILLLDEPTSAMDNRSEERF---KDRLKRWLaGKTLVLVTH-RTSLLDLVDRIIVMDNGRI 677
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 8-220 4.52e-35

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 129.05  E-value: 4.52e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   8 DVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAG-EILLAGRSIN--NVPPHKRD 84
Cdd:COG1119    1 DPLLELRNVTVRR-GGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGERRGgeDVWELRKR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 IGMV---FQNYaLFPHMTVAEnlafplTV-----------RGLSKTDVsERVKRVLSMVQLDAFAQRYPAQLSGGQQQRV 150
Cdd:COG1119   80 IGLVspaLQLR-FPRDETVLD------VVlsgffdsiglyREPTDEQR-ERARELLELLGLAHLADRPFGTLSQGEQRRV 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 151 ALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:COG1119  152 LIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRV 221
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 27-234 4.83e-35

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 130.98  E-value: 4.83e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKR-----DIGMVFQN--YALFPHMT 99
Cdd:PRK15079  37 VDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWravrsDIQMIFQDplASLNPRMT 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 100 VAENLAFPLTVR--GLSKTDVSERVKRVLSMVQL-DAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQL 176
Cdd:PRK15079 117 IGEIIAEPLRTYhpKLSRQEVKDRVKAMMLKVGLlPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSI 196

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 177 REHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPK 234
Cdd:PRK15079 197 QAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPL 254
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 11-220 7.63e-35

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 125.62  E-value: 7.63e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTsLM-MLAGFETPTAGEILLAGRSINNVPP---HKRDIG 86
Cdd:cd03216    1 LELRGITKRF-GGVKALDGVSLSVRRGEVHALLGENGAGKST-LMkILSGLYKPDSGEILVDGKEVSFASPrdaRRAGIA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 MVFQnyalfphmtvaenlafpltvrglsktdvservkrvlsmvqldafaqrypaqLSGGQQQRVALARALVFEPQLVLMD 166
Cdd:cd03216   79 MVYQ---------------------------------------------------LSVGERQMVEIARALARNARLLILD 107

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 657054004 167 EPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03216  108 EPTAALTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRV 160
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 14-232 1.00e-34

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 133.77  E-value: 1.00e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   14 RGVQKSYDGenlivkdLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEI----------------LLAGRSinn 77
Cdd:TIGR03269 294 RGVVKAVDN-------VSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVnvrvgdewvdmtkpgpDGRGRA--- 363

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   78 vpphKRDIGMVFQNYALFPHMTVAENLAFPLtvrGLSKTDVSERVKRV--LSMVQLD-----AFAQRYPAQLSGGQQQRV 150
Cdd:TIGR03269 364 ----KRYIGILHQEYDLYPHRTVLDNLTEAI---GLELPDELARMKAVitLKMVGFDeekaeEILDKYPDELSEGERHRV 436

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  151 ALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLY 230
Cdd:TIGR03269 437 ALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEIV 516


                  ..
gi 657054004  231 EE 232
Cdd:TIGR03269 517 EE 518
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 19-220 1.64e-34

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 126.87  E-value: 1.64e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   19 SYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKR---DIGMVFQNYALF 95
Cdd:TIGR03410   8 VYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERaraGIAYVPQGREIF 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   96 PHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMvqLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQ 175
Cdd:TIGR03410  88 PRLTVEENLLTGLAALPRRSRKIPDEIYELFPV--LKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEPTEGIQPS 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 657054004  176 LREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:TIGR03410 166 IIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRV 210
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 11-201 1.82e-34

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 133.18  E-value: 1.82e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGMV 88
Cdd:TIGR02857 322 LEFSGVSVAYPGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADswRDQIAWV 401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   89 FQNYALFPHmTVAENLAfpltvrgLSKTDVSE-RVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARAL 156
Cdd:TIGR02857 402 PQHPFLFAG-TIAENIR-------LARPDASDaEIREALERAGLDEFVAALPqgldtpigeggAGLSGGQAQRLALARAF 473

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 657054004  157 VFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQrlGVTVVYVTHD 201
Cdd:TIGR02857 474 LRDAPLLLLDEPTAHLDAETEAEVLEALRALAQ--GRTVLLVTHR 516
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 26-201 2.75e-34

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 126.43  E-value: 2.75e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKR------DIGMVFQNYALFPHMT 99
Cdd:PRK10584  25 ILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARaklrakHVGFVFQSFMLIPTLN 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 100 VAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREH 179
Cdd:PRK10584 105 ALENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDK 184

                        170       180
                 ....*....|....*....|..
gi 657054004 180 MQMEIKHLHQRLGVTVVYVTHD 201
Cdd:PRK10584 185 IADLLFSLNREHGTTLILVTHD 206
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 14-240 2.92e-34

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 127.50  E-value: 2.92e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN-------NVpphKRDIG 86
Cdd:PRK13639   5 RDLKYSYPDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKydkksllEV---RKTVG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 MVFQNY--ALFPHmTVAENLAF-PLTVrGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLV 163
Cdd:PRK13639  82 IVFQNPddQLFAP-TVEEDVAFgPLNL-GLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEII 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 657054004 164 LMDEPLGALDKQLREHMqMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVAN 240
Cdd:PRK13639 160 VLDEPTSGLDPMGASQI-MKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDIETIRKAN 235
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 6-234 3.31e-34

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 128.54  E-value: 3.31e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   6 SNDVLVSFRGVQKSYD-------GENLiVKDLN---LDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSI 75
Cdd:PRK11308   1 SQQPLLQAIDLKKHYPvkrglfkPERL-VKALDgvsFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  76 NNVPPH-----KRDIGMVFQN-YA-LFPHMTVAENLAFPLTVrglsKTDVS--ERVKRVLSM---VQLDA-FAQRYPAQL 142
Cdd:PRK11308  80 LKADPEaqkllRQKIQIVFQNpYGsLNPRKKVGQILEEPLLI----NTSLSaaERREKALAMmakVGLRPeHYDRYPHMF 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 143 SGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQ 222
Cdd:PRK11308 156 SGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVE 235

                        250
                 ....*....|..
gi 657054004 223 IAPPRTLYEEPK 234
Cdd:PRK11308 236 KGTKEQIFNNPR 247
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 19-212 3.46e-34

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 125.06  E-value: 3.46e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  19 SYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRdIGMVFQN--YALFP 96
Cdd:cd03226    8 SYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKERRKS-IGYVMQDvdYQLFT 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  97 HmTVAENLAfpLTVRGLSktDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDkql 176
Cdd:cd03226   87 D-SVREELL--LGLKELD--AGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLD--- 158

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 657054004 177 REHMQM---EIKHLhQRLGVTVVYVTHDQGEALTMSDRV 212
Cdd:cd03226  159 YKNMERvgeLIREL-AAQGKAVIVITHDYEFLAKVCDRV 196
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 11-220 4.10e-34

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 123.87  E-value: 4.10e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRgvqksYDG-ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNV-PPHKRD-IGM 87
Cdd:cd03246    6 VSFR-----YPGaEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWdPNELGDhVGY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFPHmTVAENLafpltvrglsktdvservkrvlsmvqldafaqrypaqLSGGQQQRVALARALVFEPQLVLMDE 167
Cdd:cd03246   81 LPQDDELFSG-SIAENI-------------------------------------LSGGQRQRLGLARALYGNPRILVLDE 122

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 657054004 168 PLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHdQGEALTMSDRVAVFHQGEI 220
Cdd:cd03246  123 PNSHLDVEGERALNQAIAALKAA-GATRIVIAH-RPETLASADRILVLEDGRV 173
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 22-222 6.04e-33

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 122.52  E-value: 6.04e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP--HKRDIGMVFQNYALFPHmT 99
Cdd:PRK10247  18 GDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPeiYRQQVSYCAQTPTLFGD-T 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 100 VAENLAFPLTVRGlsKTDVSERVKRVLSMVQL-DAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLRE 178
Cdd:PRK10247  97 VYDNLIFPWQIRN--QQPDPAIFLDDLERFALpDTILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKH 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 657054004 179 HMQMEIKHLHQRLGVTVVYVTHDQGEaLTMSDRVAVF--HQGEIQQ 222
Cdd:PRK10247 175 NVNEIIHRYVREQNIAVLWVTHDKDE-INHADKVITLqpHAGEMQE 219
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 11-229 7.05e-33

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 122.33  E-value: 7.05e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGMV 88
Cdd:cd03254    3 IEFENVNFSYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKslRSMIGVV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQNYALFPHmTVAENLAFpltvRGLSKTDvsERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARALV 157
Cdd:cd03254   83 LQDTFLFSG-TIMENIRL----GRPNATD--EEVIEAAKEAGAHDFIMKLPngydtvlgengGNLSQGERQLLAIARAML 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 158 FEPQLVLMDEPLGALDKQLREHMQMEIKHLHQrlGVTVVYVTHdqgeALTM---SDRVAVFHQGEIQQIAPPRTL 229
Cdd:cd03254  156 RDPKILILDEATSNIDTETEKLIQEALEKLMK--GRTSIIIAH----RLSTiknADKILVLDDGKIIEEGTHDEL 224
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
11-232 8.91e-33

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 123.66  E-value: 8.91e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAG---RSINNVPPHKRDIGM 87
Cdd:PRK13633  10 VSYKYESNEESTEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGldtSDEENLWDIRNKAGM 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNyalfPH-----MTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQL 162
Cdd:PRK13633  90 VFQN----PDnqivaTIVEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPEC 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 163 VLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTmSDRVAVFHQGEIQQIAPPRTLYEE 232
Cdd:PRK13633 166 IIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIFKE 234
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 11-220 1.72e-32

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 121.57  E-value: 1.72e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDG-ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGM 87
Cdd:cd03251    1 VEFKNVTFRYPGdGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLAslRRQIGL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFpHMTVAENLAFpltvrglSKTDVS-ERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARA 155
Cdd:cd03251   81 VSQDVFLF-NDTVAENIAY-------GRPGATrEEVEEAARAANAHEFIMELPegydtvigergVKLSGGQRQRIAIARA 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 156 LVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQrlGVTVVYVTHdQGEALTMSDRVAVFHQGEI 220
Cdd:cd03251  153 LLKDPPILILDEATSALDTESERLVQAALERLMK--NRTTFVIAH-RLSTIENADRIVVLEDGKI 214
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 27-237 2.29e-32

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 128.05  E-value: 2.29e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK-----RDIGMVFQN-YA-LFPHMT 99
Cdd:PRK10261 340 VEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKlqalrRDIQFIFQDpYAsLDPRQT 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 100 VAENLAFPLTVRGLSKTDVS-ERVKRVLSMVQLDA-FAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLR 177
Cdd:PRK10261 420 VGDSIMEPLRVHGLLPGKAAaARVAWLLERVGLLPeHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIR 499

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 178 EHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTF 237
Cdd:PRK10261 500 GQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPY 559
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
27-220 2.95e-32

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 121.82  E-value: 2.95e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRD--IGMVFQN--YALFPHMTVAE 102
Cdd:PRK15112  29 VKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSYRSqrIRMIFQDpsTSLNPRQRISQ 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 103 NLAFPLTVR-GLSKTDVSERVKRVLSMVQLDA-FAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHM 180
Cdd:PRK15112 109 ILDFPLRLNtDLEPEQREKQIIETLRQVGLLPdHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQL 188

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 657054004 181 QMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:PRK15112 189 INLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEV 228
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 21-220 8.14e-32

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 119.56  E-value: 8.14e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  21 DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSinnVPPhkRDIGMVFQnyalfPHMTV 100
Cdd:cd03220   32 VGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRV---SSL--LGLGGGFN-----PELTG 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 101 AENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHM 180
Cdd:cd03220  102 RENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKC 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 657054004 181 QMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03220  182 QRRLRELLKQ-GKTVILVSHDPSSIKRLCDRALVLEKGKI 220
cbiO PRK13641
energy-coupling factor transporter ATPase;
29-234 1.37e-31

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 120.70  E-value: 1.37e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  29 DLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN------NVPPHKRDIGMVFQnyalFPHM---- 98
Cdd:PRK13641  25 NISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITpetgnkNLKKLRKKVSLVFQ----FPEAqlfe 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 -TVAENLAF-PLTVrGLSKTDVSERVKRVLSMVQL-DAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQ 175
Cdd:PRK13641 101 nTVLKDVEFgPKNF-GFSEDEAKEKALKWLKKVGLsEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPE 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004 176 LREHMqMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPK 234
Cdd:PRK13641 180 GRKEM-MQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDKE 237
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
8-232 2.28e-31

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 121.48  E-value: 2.28e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   8 DVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSinnVPPHKR---- 83
Cdd:PRK13536  39 TVAIDLAGVSKSY-GDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVP---VPARARlara 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  84 DIGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLV 163
Cdd:PRK13536 115 RIGVVPQFDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLL 194

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004 164 LMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEE 232
Cdd:PRK13536 195 ILDEPTTGLDPHARHLIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHALIDE 262
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 20-242 2.55e-31

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 119.38  E-value: 2.55e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  20 YDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGF------ETPTAGEILLAGRSINNVPPHK--RDIGMVFQN 91
Cdd:PRK14246  19 YINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLieiydsKIKVDGKVLYFGKDIFQIDAIKlrKEVGMVFQQ 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  92 YALFPHMTVAENLAFPLTVRGLS-----KTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMD 166
Cdd:PRK14246  99 PNPFPHLSIYDNIAYPLKSHGIKekreiKKIVEECLRKVGLWKEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMD 178

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 167 EPLGALDKQLREHMQMEIKHLHQRlgVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFI 242
Cdd:PRK14246 179 EPTSMIDIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEKYV 252
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 27-273 2.92e-31

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 120.58  E-value: 2.92e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSinnvpPHK------RDIGMVF-QNYALFPHMT 99
Cdd:COG4586   38 VDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGYV-----PFKrrkefaRRIGVVFgQRSQLWWDLP 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 100 VAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRyPA-QLSGGQQQRVALARALVFEPQLVLMDEP-LGaLD---- 173
Cdd:COG4586  113 AIDSFRLLKAIYRIPDAEYKKRLDELVELLDLGELLDT-PVrQLSLGQRMRCELAAALLHRPKILFLDEPtIG-LDvvsk 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 174 KQLREHmqmeIKHLHQRLGVTVVYVTHDQG--EALtmSDRVAVFHQGEI----------QQIAPPRTL---YEEPKNTFV 238
Cdd:COG4586  191 EAIREF----LKEYNRERGTTILLTSHDMDdiEAL--CDRVIVIDHGRIiydgsleelkERFGPYKTIvleLAEPVPPLE 264

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 657054004 239 ANFigennrlNGRLHSHTGERCVVELARGEKVEAL 273
Cdd:COG4586  265 LPR-------GGEVIEREGNRVRLEVDPRESLAEV 292
cbiO PRK13642
energy-coupling factor transporter ATPase;
16-230 3.26e-31

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 119.43  E-value: 3.26e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  16 VQKSYDGENLIVK-----DLN------LDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN--NVPPHK 82
Cdd:PRK13642   1 MNKILEVENLVFKyekesDVNqlngvsFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTaeNVWNLR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  83 RDIGMVFQNY-ALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQ 161
Cdd:PRK13642  81 RKIGMVFQNPdNQFVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPE 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004 162 LVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTmSDRVAVFHQGEIQQIAPPRTLY 230
Cdd:PRK13642 161 IIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELF 228
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 27-220 3.60e-31

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 116.38  E-value: 3.60e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKR-DIGMVF-----QNYALFPHMTV 100
Cdd:cd03215   16 VRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAiRAGIAYvpedrKREGLVLDLSV 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 101 AENLAFPltvrglsktdvservkrvlsmvqldafaqrypAQLSGGQQQRVALARALVFEPQLVLMDEP-----LGAldkq 175
Cdd:cd03215   96 AENIALS--------------------------------SLLSGGNQQKVVLARWLARDPRVLILDEPtrgvdVGA---- 139

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 657054004 176 lrehmqmeIKHLHQRL------GVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03215  140 --------KAEIYRLIreladaGKAVLLISSELDELLGLCDRILVMYEGRI 182
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 27-218 9.00e-31

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 118.30  E-value: 9.00e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN--NVPPHKRDIGMVFQNY--ALFPhMTVAE 102
Cdd:PRK13647  21 LKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNaeNEKWVRSKVGLVFQDPddQVFS-STVWD 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 103 NLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQM 182
Cdd:PRK13647 100 DVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQETLME 179

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 657054004 183 EIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQG 218
Cdd:PRK13647 180 ILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEG 214
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 10-233 1.17e-30

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 117.98  E-value: 1.17e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN--NVPPHKRDIGM 87
Cdd:PRK13652   3 LIETRDLCYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITkeNIREVRKFVGL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNY--ALFPhMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLM 165
Cdd:PRK13652  83 VFQNPddQIFS-PTVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVL 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 166 DEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEP 233
Cdd:PRK13652 162 DEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 1-250 1.30e-30

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 119.06  E-value: 1.30e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   1 MSEVDSNDVLVSFrgvqKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTS---LMMLAGFETPTAGEILLAGRSINN 77
Cdd:PRK09473  10 DALLDVKDLRVTF----STPDGDVTAVNDLNFSLRAGETLGIVGESGSGKSQTafaLMGLLAANGRIGGSATFNGREILN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  78 VPPHK------RDIGMVFQN--YALFPHMTVAENLAFPLTV-RGLSKTDVSERVKRVLSMVQLDAFAQR---YPAQLSGG 145
Cdd:PRK09473  86 LPEKElnklraEQISMIFQDpmTSLNPYMRVGEQLMEVLMLhKGMSKAEAFEESVRMLDAVKMPEARKRmkmYPHEFSGG 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 146 QQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAP 225
Cdd:PRK09473 166 MRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGN 245

                        250       260
                 ....*....|....*....|....*
gi 657054004 226 PRTLYEEPKNTFVANFIGENNRLNG 250
Cdd:PRK09473 246 ARDVFYQPSHPYSIGLLNAVPRLDA 270
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 27-221 1.75e-30

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 116.28  E-value: 1.75e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGrsinNVP-----PHKRDIGMVF-QNYALFPHMTV 100
Cdd:cd03267   37 LKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAG----LVPwkrrkKFLRRIGVVFgQKTQLWWDLPV 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 101 AENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHM 180
Cdd:cd03267  113 IDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENI 192

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 657054004 181 QMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQ 221
Cdd:cd03267  193 RNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLL 233
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 22-225 2.40e-30

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 121.78  E-value: 2.40e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP-----HkrdIGMVFQNYALFP 96
Cdd:COG4618  343 SKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDReelgrH---IGYLPQDVELFD 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  97 HmTVAENLA-FPltvrglsktDV-SERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARALVFEPQLV 163
Cdd:COG4618  420 G-TIAENIArFG---------DAdPEKVVAAAKLAGVHEMILRLPdgydtrigeggARLSGGQRQRIGLARALYGDPRLV 489

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 657054004 164 LMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGeALTMSDRVAVFHQGEIQQIAP 225
Cdd:COG4618  490 VLDEPNSNLDDEGEAALAAAIRALKAR-GATVVVITHRPS-LLAAVDKLLVLRDGRVQAFGP 549
cbiO PRK13649
energy-coupling factor transporter ATPase;
29-232 2.85e-30

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 116.77  E-value: 2.85e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  29 DLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINN------VPPHKRDIGMVFQnyalFPHM---- 98
Cdd:PRK13649  25 DVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITStsknkdIKQIRKKVGLVFQ----FPESqlfe 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 -TVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLD-AFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQL 176
Cdd:PRK13649 101 eTVLKDVAFGPQNFGVSQEEAEALAREKLALVGISeSLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDPKG 180

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 177 REHMQMEIKHLHQrLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEE 232
Cdd:PRK13649 181 RKELMTLFKKLHQ-SGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQD 235
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 14-229 8.36e-30

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 114.80  E-value: 8.36e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGMVFQN 91
Cdd:COG4604    5 KNVSKRY-GGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRElaKRLAILRQE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  92 YALFPHMTVAENLAF---PLTvRG-LSKTDVsERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDE 167
Cdd:COG4604   84 NHINSRLTVRELVAFgrfPYS-KGrLTAEDR-EIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVLLDE 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004 168 PLGALD-KQLREHMQMeIKHLHQRLGVTVVYVTHDQGEALTMSDRV------AVFHQGEIQQIAPPRTL 229
Cdd:COG4604  162 PLNNLDmKHSVQMMKL-LRRLADELGKTVVIVLHDINFASCYADHIvamkdgRVVAQGTPEEIITPEVL 229
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 41-243 9.38e-30

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 115.58  E-value: 9.38e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  41 TLLGPSGSGKTTSLMML-------AGFETptAGEILLAGRSINN---VPPHKRDIGMVFQNYALFPhMTVAENLAFPLTV 110
Cdd:PRK14271  51 SLMGPTGSGKTTFLRTLnrmndkvSGYRY--SGDVLLGGRSIFNyrdVLEFRRRVGMLFQRPNPFP-MSIMDNVLAGVRA 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 111 RGL-SKTDVSERVKRVLSMVQL-DAFAQRY---PAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIK 185
Cdd:PRK14271 128 HKLvPRKEFRGVAQARLTEVGLwDAVKDRLsdsPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIR 207

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 186 HLHQRLgvTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIG 243
Cdd:PRK14271 208 SLADRL--TVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHAETARYVA 263
cbiO PRK13643
energy-coupling factor transporter ATPase;
29-232 1.21e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 115.60  E-value: 1.21e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  29 DLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINN------VPPHKRDIGMVFQnyalFPHM---- 98
Cdd:PRK13643  24 DIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSStskqkeIKPVRKKVGVVFQ----FPESqlfe 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 -TVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDA-FAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQL 176
Cdd:PRK13643 100 eTVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLADeFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKA 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 177 REHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEE 232
Cdd:PRK13643 180 RIEMMQLFESIHQS-GQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQE 234
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 1-227 1.63e-29

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 117.64  E-value: 1.63e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   1 MSEVDSNDVLVSFrgvqksydGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP 80
Cdd:PRK09536   1 MPMIDVSDLSVEF--------GDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  81 HK--RDIGMVFQNYAL---FPHMTVAENLAFPLTVRGLSKTDVSER-VKRVLSMVQLDAFAQRYPAQLSGGQQQRVALAR 154
Cdd:PRK09536  73 RAasRRVASVPQDTSLsfeFDVRQVVEMGRTPHRSRFDTWTETDRAaVERAMERTGVAQFADRPVTSLSGGERQRVLLAR 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 155 ALVFEPQLVLMDEPLGALDKqlreHMQMEIKHLHQRL---GVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPR 227
Cdd:PRK09536 153 ALAQATPVLLLDEPTASLDI----NHQVRTLELVRRLvddGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPA 224
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 11-200 2.09e-29

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 119.14  E-value: 2.09e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQ-KSYDGEnLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLagrsinnvPPHKRdigMVF 89
Cdd:COG4178  363 LALEDLTlRTPDGR-PLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIAR--------PAGAR---VLF 430

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 ---QNYalFPHMTVAENLAFPLTVRGLSktdvSERVKRVLSMVQLDAFAQRY------PAQLSGGQQQRVALARALVFEP 160
Cdd:COG4178  431 lpqRPY--LPLGTLREALLYPATAEAFS----DAELREALEAVGLGHLAERLdeeadwDQVLSLGEQQRLAFARLLLHKP 504

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 657054004 161 QLVLMDEPLGALDKQLREHMqmeIKHLHQRL-GVTVVYVTH 200
Cdd:COG4178  505 DWLFLDEATSALDEENEAAL---YQLLREELpGTTVISVGH 542
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 11-229 2.48e-29

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 113.09  E-value: 2.48e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGMV 88
Cdd:cd03253    1 IEFENVTFAYDPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDslRRAIGVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQNYALFpHMTVAENLAFpltvrG-LSKTDvsERVKRVLSMVQLDAFAQRYPAQ-----------LSGGQQQRVALARAL 156
Cdd:cd03253   81 PQDTVLF-NDTIGYNIRY-----GrPDATD--EEVIEAAKAAQIHDKIMRFPDGydtivgerglkLSGGEKQRVAIARAI 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 157 VFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQrlGVTVVYVTHDQGEALTmSDRVAVFHQGEIQQIAPPRTL 229
Cdd:cd03253  153 LKNPPILLLDEATSALDTHTEREIQAALRDVSK--GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTHEEL 222
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 20-215 5.04e-29

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 113.34  E-value: 5.04e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  20 YDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLM-------MLAGFETptAGEILLAGRSIN--NVPPH--KRDIGMV 88
Cdd:PRK14243  19 YYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRcfnrlndLIPGFRV--EGKVTFHGKNLYapDVDPVevRRRIGMV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQNYALFPHmTVAENLAFPLTVRGLsKTDVSERVKRVLSMVQL-----DAFAQRYPAqLSGGQQQRVALARALVFEPQLV 163
Cdd:PRK14243  97 FQKPNPFPK-SIYDNIAYGARINGY-KGDMDELVERSLRQAALwdevkDKLKQSGLS-LSGGQQQRLCIARAIAVQPEVI 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 657054004 164 LMDEPLGALDKQLREHMQMEIKHLHQRLgvTVVYVTHDQGEALTMSDRVAVF 215
Cdd:PRK14243 174 LMDEPCSALDPISTLRIEELMHELKEQY--TIIIVTHNMQQAARVSDMTAFF 223
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 22-221 8.32e-29

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 117.06  E-value: 8.32e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGMVFQNYALFPHmT 99
Cdd:TIGR01842 329 GKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETfgKHIGYLPQDVELFPG-T 407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  100 VAENLAfpltvRGLSKTDvSERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARALVFEPQLVLMDEP 168
Cdd:TIGR01842 408 VAENIA-----RFGENAD-PEKIIEAAKLAGVHELILRLPdgydtvigpggATLSGGQRQRIALARALYGDPKLVVLDEP 481

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 657054004  169 LGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGeALTMSDRVAVFHQGEIQ 221
Cdd:TIGR01842 482 NSNLDEEGEQALANAIKALKAR-GITVVVITHRPS-LLGCVDKILVLQDGRIA 532
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 12-232 9.07e-29

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 112.10  E-value: 9.07e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  12 SFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSinnVPPhkRDIGMVFQn 91
Cdd:COG1134   27 LLLRRRRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRV---SAL--LELGAGFH- 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  92 yalfPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFA----QRYpaqlSGGQQQRVALARALVFEPQLVLMDE 167
Cdd:COG1134  101 ----PELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIdqpvKTY----SSGMRARLAFAVATAVDPDILLVDE 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 168 PLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRT---LYEE 232
Cdd:COG1134  173 VLAVGDAAFQKKCLARIRELRES-GRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEviaAYEA 239
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 20-242 2.07e-28

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 111.41  E-value: 2.07e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  20 YDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGF-----ETPTAGEILLAGRSI----NNVPPHKRDIGMVFQ 90
Cdd:PRK14239  14 YYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndlnpEVTITGSIVYNGHNIysprTDTVDLRKEIGMVFQ 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NYALFPhMTVAENLAFPLTVRGL-SKTDVSERVKRVLSMVQL-DAFAQRYPAQ---LSGGQQQRVALARALVFEPQLVLM 165
Cdd:PRK14239  94 QPNPFP-MSIYENVVYGLRLKGIkDKQVLDEAVEKSLKGASIwDEVKDRLHDSalgLSGGQQQRVCIARVLATSPKIILL 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 166 DEPLGALD----KQLREHMqMEIKHLHqrlgvTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANF 241
Cdd:PRK14239 173 DEPTSALDpisaGKIEETL-LGLKDDY-----TMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFMNPKHKETEDY 246


                 .
gi 657054004 242 I 242
Cdd:PRK14239 247 I 247
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
30-220 2.14e-28

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 111.64  E-value: 2.14e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  30 LNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFET---PTAGEILLAGRSINNVPPHKRDI-------GMVFQNYALFPHMT 99
Cdd:PRK09984  23 VDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITgdkSAGSHIELLGRTVQREGRLARDIrksrantGYIFQQFNLVNRLS 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 100 VAEN-LAFPLTVRGLSKTDVS-------ERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGA 171
Cdd:PRK09984 103 VLENvLIGALGSTPFWRTCFSwftreqkQRALQALTRVGMVHFAHQRVSTLSGGQQQRVAIARALMQQAKVILADEPIAS 182

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 657054004 172 LDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:PRK09984 183 LDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHV 231
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
27-232 3.57e-28

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 114.73  E-value: 3.57e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH---KRDIGMVFQN---YALFPHMTV 100
Cdd:COG1129  268 VRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRdaiRAGIAYVPEDrkgEGLVLDLSI 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 101 AENLAFPlTVRGLSKtdvservKRVLSMVQLDAFAQRY----------PAQ----LSGGQQQRVALARALVFEPQLVLMD 166
Cdd:COG1129  348 RENITLA-SLDRLSR-------GGLLDRRRERALAEEYikrlriktpsPEQpvgnLSGGNQQKVVLAKWLATDPKVLILD 419

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 657054004 167 EP-----LGAldKQlrehmqmEIKHLHQRL---GVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEE 232
Cdd:COG1129  420 EPtrgidVGA--KA-------EIYRLIRELaaeGKAVIVISSELPELLGLSDRILVMREGRIVGELDREEATEE 484
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
27-212 3.86e-28

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 108.86  E-value: 3.86e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGrsinnvpphKRDIGMVFQnyalfpHMTVAEnlAF 106
Cdd:NF040873   8 LHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAG---------GARVAYVPQ------RSEVPD--SL 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 107 PLTVRG---------------LSKTDvSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGA 171
Cdd:NF040873  71 PLTVRDlvamgrwarrglwrrLTRDD-RAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTG 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 657054004 172 LDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRV 212
Cdd:NF040873 150 LDAESRERIIALLAEEHAR-GATVVVVTHDLELVRRADPCV 189
cbiO PRK13645
energy-coupling factor transporter ATPase;
31-230 4.59e-28

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 111.25  E-value: 4.59e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  31 NLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAG-------RSINNVPPHKRDIGMVFQ--NYALFPHmTVA 101
Cdd:PRK13645  31 SLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDyaipanlKKIKEVKRLRKEIGLVFQfpEYQLFQE-TIE 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 102 ENLAFPLTVRGLSKTDVSERVKRVLSMVQL-DAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHM 180
Cdd:PRK13645 110 KDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDF 189

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 657054004 181 QMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLY 230
Cdd:PRK13645 190 INLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIF 239
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 13-201 1.07e-27

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 113.99  E-value: 1.07e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   13 FRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGMVFQ 90
Cdd:TIGR02868 337 LRDLSAGYPGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDevRRRVSVCAQ 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   91 NYALFpHMTVAENLAfpltvrgLSKTDVS-ERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARALVF 158
Cdd:TIGR02868 417 DAHLF-DTTVRENLR-------LARPDATdEELWAALERVGLADWLRALPdgldtvlgeggARLSGGERQRLALARALLA 488

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 657054004  159 EPQLVLMDEPLGALDKQLREHMqmeIKHLHQRL-GVTVVYVTHD 201
Cdd:TIGR02868 489 DAPILLLDEPTEHLDAETADEL---LEDLLAALsGRTVVLITHH 529
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 22-193 1.93e-27

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 107.06  E-value: 1.93e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH-KRDIGMVFQNYALFPHMTV 100
Cdd:TIGR01189  11 GERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEpHENILYLGHLPGLKPELSA 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  101 AENLAFPLTVRGLSKTDVSErvkrVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQ----- 175
Cdd:TIGR01189  91 LENLHFWAAIHGGAQRTIED----ALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAgvall 166

                         170       180
                  ....*....|....*....|....
gi 657054004  176 ---LREHMQ---MEIKHLHQRLGV 193
Cdd:TIGR01189 167 aglLRAHLArggIVLLTTHQDLGL 190
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 8-232 2.57e-27

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 109.17  E-value: 2.57e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   8 DVLVSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN----NVPPHKR 83
Cdd:PRK13636   3 DYILKVEELNYNYSDGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDysrkGLMKLRE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  84 DIGMVFQ--NYALFPhMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQ 161
Cdd:PRK13636  83 SVGMVFQdpDNQLFS-ASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPK 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657054004 162 LVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEE 232
Cdd:PRK13636 162 VLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVFAE 232
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
22-200 2.84e-27

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 106.81  E-value: 2.84e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRD----IGmvFQNyALFPH 97
Cdd:PRK13538  12 DERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEYHQdllyLG--HQP-GIKTE 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  98 MTVAENLAFPLTVRGLSKTDvseRVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQ-- 175
Cdd:PRK13538  89 LTALENLRFYQRLHGPGDDE---ALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQgv 165

                        170       180
                 ....*....|....*....|....*..
gi 657054004 176 --LREHMQmeiKHLHQrlGVTVVYVTH 200
Cdd:PRK13538 166 arLEALLA---QHAEQ--GGMVILTTH 187
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 10-233 6.92e-27

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 112.12  E-value: 6.92e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   10 LVSFRGVQKSYDG--ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDI 85
Cdd:TIGR00958 478 LIEFQDVSFSYPNrpDVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHylHRQV 557

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   86 GMVFQNYALFPHmTVAENLAFpltvrGLSKTDvSERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALAR 154
Cdd:TIGR00958 558 ALVGQEPVLFSG-SVRENIAY-----GLTDTP-DEEIMAAAKAANAHDFIMEFPngydtevgekgSQLSGGQKQRIAIAR 630

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004  155 ALVFEPQLVLMDEPLGALDKQLREHMQmeikHLHQRLGVTVVYVTHdQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEP 233
Cdd:TIGR00958 631 ALVRKPRVLILDEATSALDAECEQLLQ----ESRSRASRTVLLIAH-RLSTVERADQILVLKKGSVVEMGTHKQLMEDQ 704
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 11-220 7.09e-27

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 106.80  E-value: 7.09e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDG-ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGM 87
Cdd:cd03252    1 ITFEHVRFRYKPdGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAwlRRQVGV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFpHMTVAENLAfpLTVRGLSKtdvsERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARAL 156
Cdd:cd03252   81 VLQENVLF-NRSIRDNIA--LADPGMSM----ERVIEAAKLAGAHDFISELPegydtivgeqgAGLSGGQRQRIAIARAL 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 157 VFEPQLVLMDEPLGALDKQlREHMQMeiKHLHQRL-GVTVVYVTHdQGEALTMSDRVAVFHQGEI 220
Cdd:cd03252  154 IHNPRILIFDEATSALDYE-SEHAIM--RNMHDICaGRTVIIIAH-RLSTVKNADRIIVMEKGRI 214
NHLM_micro_ABC2 TIGR03797
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ...
 11-233 8.01e-27

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274789 [Multi-domain]  Cd Length: 686  Bit Score: 111.97  E-value: 8.01e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   11 VSFRgvqksYDGE-NLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN--NVPPHKRDIGM 87
Cdd:TIGR03797 457 VTFR-----YRPDgPLILDDVSLQIEPGEFVAIVGPSGSGKSTLLRLLLGFETPESGSVFYDGQDLAglDVQAVRRQLGV 531

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   88 VFQNYALFPHmTVAENLA--FPLTVrglsktdvsERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALAR 154
Cdd:TIGR03797 532 VLQNGRLMSG-SIFENIAggAPLTL---------DEAWEAARMAGLAEDIRAMPmgmhtviseggGTLSGGQRQRLLIAR 601

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  155 ALVFEPQLVLMDEPLGALDKQLREHMQMEIKhlhqRLGVTVVYVTHdqgealTMS-----DRVAVFHQGEIQQIAPPRTL 229
Cdd:TIGR03797 602 ALVRKPRILLFDEATSALDNRTQAIVSESLE----RLKVTRIVIAH------RLStirnaDRIYVLDAGRVVQQGTYDEL 671


                  ....
gi 657054004  230 YEEP 233
Cdd:TIGR03797 672 MARE 675
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 18-248 8.02e-27

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 106.52  E-value: 8.02e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  18 KSYDGENlIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH---KRDIGMVFQNYAL 94
Cdd:PRK10895  11 KAYKGRR-VVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHaraRRGIGYLPQEASI 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  95 FPHMTVAENLAFPLTVR-GLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALD 173
Cdd:PRK10895  90 FRRLSVYDNLMAVLQIRdDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVD 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 174 KQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVanFIGENNRL 248
Cdd:PRK10895 170 PISVIDIKRIIEHLRDS-GLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRV--YLGEDFRL 241
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 11-220 9.08e-27

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 104.94  E-value: 9.08e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENL-----IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTA--GEILLAGRsinNVPPH-- 81
Cdd:cd03213    4 LSFRNLTVTVKSSPSksgkqLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLGvsGEVLINGR---PLDKRsf 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  82 KRDIGMVFQNYALFPHMTVAENLAFPLTVRGlsktdvservkrvlsmvqldafaqrypaqLSGGQQQRVALARALVFEPQ 161
Cdd:cd03213   81 RKIIGYVPQDDILHPTLTVRETLMFAAKLRG-----------------------------LSGGERKRVSIALELVSNPS 131

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 162 LVLMDEPLGALDKQLREHMQMEIKHLHQrLGVTVVYVTHD-QGEALTMSDRVAVFHQGEI 220
Cdd:cd03213  132 LLFLDEPTSGLDSSSALQVMSLLRRLAD-TGRTIICSIHQpSSEIFELFDKLLLLSQGRV 190
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 6-220 1.03e-26

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 106.55  E-value: 1.03e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   6 SNDVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVP------ 79
Cdd:PRK11701   2 MDQPLLSVRGLTKLY-GPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDlyalse 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  80 PHKR-----DIGMVFQNYA--LFPHMTVAENLAFPLTVRGLSK-TDVSERVKRVLSMVQLDAfaQR---YPAQLSGGQQQ 148
Cdd:PRK11701  81 AERRrllrtEWGFVHQHPRdgLRMQVSAGGNIGERLMAVGARHyGDIRATAGDWLERVEIDA--ARiddLPTTFSGGMQQ 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 657054004 149 RVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:PRK11701 159 RLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRV 230
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
22-232 1.42e-26

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 106.25  E-value: 1.42e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGMVFQNYALFPHMT 99
Cdd:PRK11231  13 GTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQlaRRLALLPQHHLTPEGIT 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 100 VAENLAF---P-LTVRG-LSKTDvSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDK 174
Cdd:PRK11231  93 VRELVAYgrsPwLSLWGrLSAED-NARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDI 171

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 657054004 175 QlreHmQMEIKHLHQRL---GVTVVYVTHDQGEALTMSDRVAVFHQGE-IQQIAPPRTLYEE 232
Cdd:PRK11231 172 N---H-QVELMRLMRELntqGKTVVTVLHDLNQASRYCDHLVVLANGHvMAQGTPEEVMTPG 229
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 10-220 1.85e-26

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 106.07  E-value: 1.85e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   10 LVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRS-----INNVPPHKR- 83
Cdd:TIGR02323   3 LLQVSGLSKSY-GGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRSgaeleLYQLSEAERr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   84 -----DIGMVFQNYALFPHMTVAE--NLAFPLTVRGLSK-TDVSERVKRVLSMVQLD-AFAQRYPAQLSGGQQQRVALAR 154
Cdd:TIGR02323  82 rlmrtEWGFVHQNPRDGLRMRVSAgaNIGERLMAIGARHyGNIRATAQDWLEEVEIDpTRIDDLPRAFSGGMQQRLQIAR 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004  155 ALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:TIGR02323 162 NLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRV 227
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 3-248 1.96e-26

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 110.72  E-value: 1.96e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   3 EVDSNDVL------VSFRGVQKSYDGenliVKDLNLDIRKGEFLTLLGPSGSGKTT---SLMML---AGFETpTAGEILL 70
Cdd:PRK10261   6 ELDARDVLavenlnIAFMQEQQKIAA----VRNLSFSLQRGETLAIVGESGSGKSVtalALMRLleqAGGLV-QCDKMLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  71 AGRSINNVPPHKR-----------DIGMVFQN--YALFPHMTVAENLAFPLTV-RGLSKTDVSERVKRVLSMVQL---DA 133
Cdd:PRK10261  81 RRRSRQVIELSEQsaaqmrhvrgaDMAMIFQEpmTSLNPVFTVGEQIAESIRLhQGASREEAMVEAKRMLDQVRIpeaQT 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 134 FAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVA 213
Cdd:PRK10261 161 ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVL 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 657054004 214 VFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRL 248
Cdd:PRK10261 241 VMYQGEAVETGSVEQIFHAPQHPYTRALLAAVPQL 275
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 2-220 2.41e-26

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 110.30  E-value: 2.41e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   2 SEVDSNDVLVSFRGVQKSYDGENLIV-KDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP 80
Cdd:PRK11160 330 STAAADQVSLTLNNVSFTYPDQPQPVlKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSE 409

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  81 H--KRDIGMVFQNYALFPHmTVAENLAFPLTvrglSKTDvsERVKRVLSMVQLDAFAQRYPA----------QLSGGQQQ 148
Cdd:PRK11160 410 AalRQAISVVSQRVHLFSA-TLRDNLLLAAP----NASD--EALIEVLQQVGLEKLLEDDKGlnawlgeggrQLSGGEQR 482

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 149 RVALARALVFEPQLVLMDEPLGALDKQ--------LREHMQmeikhlhqrlGVTVVYVTHdQGEALTMSDRVAVFHQGEI 220
Cdd:PRK11160 483 RLGIARALLHDAPLLLLDEPTEGLDAEterqilelLAEHAQ----------NKTVLMITH-RLTGLEQFDRICVMDNGQI 551
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 10-220 5.40e-26

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 104.09  E-value: 5.40e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDG--ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPpHK---RD 84
Cdd:cd03248   11 IVKFQNVTFAYPTrpDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYE-HKylhSK 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 IGMVFQNYALFPHmTVAENLAFPLTvrglsktDVS-ERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVAL 152
Cdd:cd03248   90 VSLVGQEPVLFAR-SLQDNIAYGLQ-------SCSfECVKEAAQKAHAHSFISELAsgydtevgekgSQLSGGQKQRVAI 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 153 ARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRlgVTVVYVTHdQGEALTMSDRVAVFHQGEI 220
Cdd:cd03248  162 ARALIRNPQVLILDEATSALDAESEQQVQQALYDWPER--RTVLVIAH-RLSTVERADQILVLDGGRI 226
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 11-226 6.00e-26

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 103.73  E-value: 6.00e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSY-DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTslMMLAGFET--PTAGEILLAGRSINNVPPHK--RDI 85
Cdd:cd03244    3 IEFKNVSLRYrPNLPPVLKNISFSIKPGEKVGIVGRTGSGKSS--LLLALFRLveLSSGSILIDGVDISKIGLHDlrSRI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 GMVFQNYALFPHmTVAENLAfPLTVrglsKTDvsERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALAR 154
Cdd:cd03244   81 SIIPQDPVLFSG-TIRSNLD-PFGE----YSD--EELWQALERVGLKEFVESLPggldtvveeggENLSVGQRQLLCLAR 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 657054004 155 ALVFEPQLVLMDEPLGALDKQLREHMQMEIKhlHQRLGVTVVYVTHdQGEALTMSDRVAVFHQGEIQQIAPP 226
Cdd:cd03244  153 ALLRKSKILVLDEATASVDPETDALIQKTIR--EAFKDCTVLTIAH-RLDTIIDSDRILVLDKGRVVEFDSP 221
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 19-222 6.74e-26

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 108.78  E-value: 6.74e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  19 SYDGENLiVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFeTPTAGEILLAGRSINNVPPH--KRDIGMVFQNYALFp 96
Cdd:PRK11174 359 SPDGKTL-AGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGF-LPYQGSLKINGIELRELDPEswRKHLSWVGQNPQLP- 435

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  97 HMTVAENLAfpltvrgLSKTDVS-ERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARALVFEPQLVL 164
Cdd:PRK11174 436 HGTLRDNVL-------LGNPDASdEQLQQALENAWVSEFLPLLPqgldtpigdqaAGLSVGQAQRLALARALLQPCQLLL 508

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 165 MDEPLGALDKQLREHMQMEIKHLHQRLgvTVVYVTHdQGEALTMSDRVAVFHQGEIQQ 222
Cdd:PRK11174 509 LDEPTASLDAHSEQLVMQALNAASRRQ--TTLMVTH-QLEDLAQWDQIWVMQDGQIVQ 563
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 6-233 1.06e-25

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 105.32  E-value: 1.06e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   6 SNDVLVSFRGVQKSYD----GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEI------------- 68
Cdd:PRK13631  17 SDDIILRVKNLYCVFDekqeNELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIqvgdiyigdkknn 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  69 -----LLAGRSINNVPPHKRDIGMVFQ--NYALFPHmTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLD-AFAQRYPA 140
Cdd:PRK13631  97 helitNPYSKKIKNFKELRRRVSMVFQfpEYQLFKD-TIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLDdSYLERSPF 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 141 QLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQlREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:PRK13631 176 GLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPK-GEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKI 254

                        250
                 ....*....|...
gi 657054004 221 QQIAPPRTLYEEP 233
Cdd:PRK13631 255 LKTGTPYEIFTDQ 267
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 17-220 1.09e-25

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 103.12  E-value: 1.09e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  17 QKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAG---FETPTAGEILLAGRSINnvpPH--KRDIGMVFQN 91
Cdd:cd03234   13 AKNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGrveGGGTTSGQILFNGQPRK---PDqfQKCVAYVRQD 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  92 YALFPHMTVAENLAFPLTVRGLSKTDVSERVKRV----LSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDE 167
Cdd:cd03234   90 DILLPGLTVRETLTYTAILRLPRKSSDAIRKKRVedvlLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDE 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 657054004 168 PLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQG-EALTMSDRVAVFHQGEI 220
Cdd:cd03234  170 PTSGLDSFTALNLVSTLSQLARR-NRIVILTIHQPRsDLFRLFDRILLLSSGEI 222
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 8-232 1.62e-25

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 107.42  E-value: 1.62e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   8 DVLVSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK-RDIG 86
Cdd:COG3845  255 EVVLEVENLSVRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRErRRLG 334

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 MVF-----QNYALFPHMTVAENLAF------PLTVRG-LSKTDVSERVKRVLsmvqlDAFAQRYP------AQLSGGQQQ 148
Cdd:COG3845  335 VAYipedrLGRGLVPDMSVAENLILgryrrpPFSRGGfLDRKAIRAFAEELI-----EEFDVRTPgpdtpaRSLSGGNQQ 409

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 149 RVALARALVFEPQLVLMDEP-----LGAldkqlrehmqmeIKHLHQRL------GVTVVYVTHDQGEALTMSDRVAVFHQ 217
Cdd:COG3845  410 KVILARELSRDPKLLIAAQPtrgldVGA------------IEFIHQRLlelrdaGAAVLLISEDLDEILALSDRIAVMYE 477

                        250
                 ....*....|....*
gi 657054004 218 GEIQQIAPPRTLYEE 232
Cdd:COG3845  478 GRIVGEVPAAEATRE 492
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 27-241 1.62e-25

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 108.56  E-value: 1.62e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSI-NNVPPHKRDIGMVFQNYALFPHMTVAENLA 105
Cdd:TIGR01257  946 VDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIeTNLDAVRQSLGMCPQHNILFHHLTVAEHIL 1025

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   106 FPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIk 185
Cdd:TIGR01257 1026 FYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLL- 1104

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004   186 hLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLyeepKNTFVANF 241
Cdd:TIGR01257 1105 -LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFL----KNCFGTGF 1155
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 11-219 1.83e-25

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 101.78  E-value: 1.83e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGE----NLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRsinnvpphkrdIG 86
Cdd:cd03250    1 ISVEDASFTWDSGeqetSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS-----------IA 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 MVFQNYALFPhMTVAENLAFpltvrgLSKTDvSERVKRVLSMVQLDAFAQRYPAQ-----------LSGGQQQRVALARA 155
Cdd:cd03250   70 YVSQEPWIQN-GTIRENILF------GKPFD-EERYEKVIKACALEPDLEILPDGdlteigekginLSGGQKQRISLARA 141

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 156 LVFEPQLVLMDEPLGALDKQLREH-MQMEIKHlHQRLGVTVVYVTHdQGEALTMSDRVAVFHQGE 219
Cdd:cd03250  142 VYSDADIYLLDDPLSAVDAHVGRHiFENCILG-LLLNNKTRILVTH-QLQLLPHADQIVVLDNGR 204
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
26-226 1.91e-25

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 103.55  E-value: 1.91e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN----NVPPHKRDIGMVFQN--YALFpHMT 99
Cdd:PRK13638  16 VLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDyskrGLLALRQQVATVFQDpeQQIF-YTD 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 100 VAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRyPAQ-LSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLRE 178
Cdd:PRK13638  95 IDSDIAFSLRNLGVPEAEITRRVDEALTLVDAQHFRHQ-PIQcLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRT 173

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 657054004 179 HMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPP 226
Cdd:PRK13638 174 QMIAIIRRIVAQ-GNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAP 220
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 19-219 3.51e-25

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 102.81  E-value: 3.51e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  19 SYDGENlIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGF-----ETPTAGEILLAGRSIN----NVPPHKRDIGMVF 89
Cdd:PRK14258  16 YYDTQK-ILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMnelesEVRVEGRVEFFNQNIYerrvNLNRLRRQVSMVH 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 QNYALFPhMTVAENLAFPLTVRGL-SKTDVSERVKRVLSMVQL-DAFAQRY---PAQLSGGQQQRVALARALVFEPQLVL 164
Cdd:PRK14258  95 PKPNLFP-MSVYDNVAYGVKIVGWrPKLEIDDIVESALKDADLwDEIKHKIhksALDLSGGQQQRLCIARALAVKPKVLL 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 165 MDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGE 219
Cdd:PRK14258 174 MDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGNE 228
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 26-220 5.30e-25

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 101.68  E-value: 5.30e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFE--TPTAGEILLAGRSINNVPPHKR---DIGMVFQNYALFPHMTV 100
Cdd:COG0396   15 ILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPkyEVTSGSILLDGEDILELSPDERaraGIFLAFQYPVEIPGVSV 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 101 AENLAFPLTVRGLSKTDVSE---RVKRVLSMVQLDA-FAQRYPAQ-LSGGQQQRVALARALVFEPQLVLMDEPLGALD-- 173
Cdd:COG0396   95 SNFLRTALNARRGEELSAREflkLLKEKMKELGLDEdFLDRYVNEgFSGGEKKRNEILQMLLLEPKLAILDETDSGLDid 174

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 657054004 174 --KQLREhmqmEIKHLHQRlGVTVVYVTH-----DQGEAltmsDRVAVFHQGEI 220
Cdd:COG0396  175 alRIVAE----GVNKLRSP-DRGILIITHyqrilDYIKP----DFVHVLVDGRI 219
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 27-212 9.24e-25

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 100.59  E-value: 9.24e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILL--AGRSIN--NVPPH------KRDIGMVFQnyalF- 95
Cdd:COG4778   27 LDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVrhDGGWVDlaQASPReilalrRRTIGYVSQ----Fl 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  96 ---PHMT----VAEnlafPLTVRGLSKTDVSERVKRVLSMVQLDafaQR----YPAQLSGGQQQRVALARALVFEPQLVL 164
Cdd:COG4778  103 rviPRVSaldvVAE----PLLERGVDREEARARARELLARLNLP---ERlwdlPPATFSGGEQQRVNIARGFIADPPLLL 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 657054004 165 MDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRV 212
Cdd:COG4778  176 LDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRV 222
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 11-220 1.28e-24

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 98.92  E-value: 1.28e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGEN-LIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRD-IGMV 88
Cdd:cd03247    1 LSINNVSFSYPEQEqQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKALSSlISVL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQNYALFpHMTVAENLAfpltvrglsktdvservkrvlsmvqldafaqrypAQLSGGQQQRVALARALVFEPQLVLMDEP 168
Cdd:cd03247   81 NQRPYLF-DTTLRNNLG----------------------------------RRFSGGERQRLALARILLQDAPIVLLDEP 125

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 657054004 169 LGALDKQL-REHMQMEIKHLHQRlgvTVVYVTHdQGEALTMSDRVAVFHQGEI 220
Cdd:cd03247  126 TVGLDPITeRQLLSLIFEVLKDK---TLIWITH-HLTGIEHMDKILFLENGKI 174
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
9-220 1.63e-24

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 100.34  E-value: 1.63e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   9 VLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK---RDI 85
Cdd:PRK11614   4 VMLSFDKVSAHY-GKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKimrEAV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 GMVFQNYALFPHMTVAENLAfpltVRGL--SKTDVSERVKRVLSMVQ--LDAFAQRyPAQLSGGQQQRVALARALVFEPQ 161
Cdd:PRK11614  83 AIVPEGRRVFSRMTVEENLA----MGGFfaERDQFQERIKWVYELFPrlHERRIQR-AGTMSGGEQQMLAIGRALMSQPR 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004 162 LVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:PRK11614 158 LLLLDEPSLGLAPIIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHV 215
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 10-220 2.78e-24

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 103.98  E-value: 2.78e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGENlIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP---HKRDIG 86
Cdd:PRK15439  11 LLCARSISKQYSGVE-VLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPakaHQLGIY 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 MVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAqrypAQLSGGQQQRVALARALVFEPQLVLMD 166
Cdd:PRK15439  90 LVPQEPLLFPNLSVKENILFGLPKRQASMQKMKQLLAALGCQLDLDSSA----GSLEVADRQIVEILRGLMRDSRILILD 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 657054004 167 EPLGALDKQLREHMQMEIKHLhQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:PRK15439 166 EPTASLTPAETERLFSRIREL-LAQGVGIVFISHKLPEIRQLADRISVMRDGTI 218
cbiO PRK13646
energy-coupling factor transporter ATPase;
17-234 5.67e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 99.85  E-value: 5.67e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  17 QKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINN------VPPHKRDIGMVFQ 90
Cdd:PRK13646  13 QKGTPYEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHktkdkyIRPVRKRIGMVFQ 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 nyalFPHM-----TVAENLAFPLTVRGLSKTDVSERVKRVLsmVQLdAFA----QRYPAQLSGGQQQRVALARALVFEPQ 161
Cdd:PRK13646  93 ----FPESqlfedTVEREIIFGPKNFKMNLDEVKNYAHRLL--MDL-GFSrdvmSQSPFQMSGGQMRKIAIVSILAMNPD 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 162 LVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPK 234
Cdd:PRK13646 166 IIVLDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKK 238
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 22-174 7.19e-24

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 97.64  E-value: 7.19e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNvPPHKRDIGMVFQNYALFPHMTVA 101
Cdd:PRK13539  13 GGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDD-PDVAEACHYLGHRNAMKPALTVA 91

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 102 ENLAFPLTVRGLSKTDVSErvkrVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDK 174
Cdd:PRK13539  92 ENLEFWAAFLGGEELDIAA----ALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDA 160
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 7-237 7.60e-24

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 102.48  E-value: 7.60e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   7 NDVLVSFRgvqkSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKT-TSLMMLAGFETP----TAGEILLAGRSINNVPPH 81
Cdd:PRK15134   9 ENLSVAFR----QQQTVRTVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPpvvyPSGDIRFHGESLLHASEQ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  82 K------RDIGMVFQN--YALFPHMTVAENLAFPLTV-RGLSKTDVSERVKRVLSMVQLDAFAQR---YPAQLSGGQQQR 149
Cdd:PRK15134  85 TlrgvrgNKIAMIFQEpmVSLNPLHTLEKQLYEVLSLhRGMRREAARGEILNCLDRVGIRQAAKRltdYPHQLSGGERQR 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 150 VALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTL 229
Cdd:PRK15134 165 VMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATL 244


                 ....*...
gi 657054004 230 YEEPKNTF 237
Cdd:PRK15134 245 FSAPTHPY 252
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 11-173 1.32e-23

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 102.21  E-value: 1.32e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGMV 88
Cdd:COG5265  358 VRFENVSFGYDPERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQAslRAAIGIV 437

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQNYALFpHMTVAENLAFpltvrglSKTDVS-ERVKRVLSMVQLDAFAQRYPAQ-----------LSGGQQQRVALARAL 156
Cdd:COG5265  438 PQDTVLF-NDTIAYNIAY-------GRPDASeEEVEAAARAAQIHDFIESLPDGydtrvgerglkLSGGEKQRVAIARTL 509

                        170
                 ....*....|....*..
gi 657054004 157 VFEPQLVLMDEPLGALD 173
Cdd:COG5265  510 LKNPPILIFDEATSALD 526
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 30-220 3.24e-23

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 96.83  E-value: 3.24e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  30 LNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFeTPTAGEILLAGRSINNVPPHK--RDIGMVFQNYALFPHMTVAENLAFp 107
Cdd:COG4138   15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGL-LPGQGEILLNGRPLSDWSAAElaRHRAYLSQQQSPPFAMPVFQYLAL- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 108 ltvrGLSKTDVSERVKRVLSMV----QLDAFAQRYPAQLSGGQQQRVALARALV-------FEPQLVLMDEPL------- 169
Cdd:COG4138   93 ----HQPAGASSEAVEQLLAQLaealGLEDKLSRPLTQLSGGEWQRVRLAAVLLqvwptinPEGQLLLLDEPMnsldvaq 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 657054004 170 -GALDKQLREhmqmeikhLHQrLGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:COG4138  169 qAALDRLLRE--------LCQ-QGITVVMSSHDLNHTLRHADRVWLLKQGKL 211
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 22-220 3.29e-23

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 95.67  E-value: 3.29e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFE--TPTAGEILLAGRSINNVPPHKR---DIGMVFQNYALFP 96
Cdd:cd03217   11 GGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEILFKGEDITDLPPEERarlGIFLAFQYPPEIP 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  97 HMTVAENLafpltvRGLSKTdvservkrvlsmvqldafaqrypaqLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQL 176
Cdd:cd03217   91 GVKNADFL------RYVNEG-------------------------FSGGEKKRNEILQLLLLEPDLAILDEPDSGLDIDA 139

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 657054004 177 REHMQMEIKHLHQRlGVTVVYVTHDQGEALTM-SDRVAVFHQGEI 220
Cdd:cd03217  140 LRLVAEVINKLREE-GKSVLIITHYQRLLDYIkPDRVHVLYDGRI 183
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 22-193 2.20e-22

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 93.33  E-value: 2.20e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP-HKRDIGMVFQNYALFPHMTV 100
Cdd:cd03231   11 DGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDsIARGLLYLGHAPGIKTTLSV 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 101 AENLAFpltvrgLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDK------ 174
Cdd:cd03231   91 LENLRF------WHADHSDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKagvarf 164

                        170       180
                 ....*....|....*....|....
gi 657054004 175 --QLREHMQ---MEIKHLHQRLGV 193
Cdd:cd03231  165 aeAMAGHCArggMVVLTTHQDLGL 188
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
10-218 2.97e-22

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 97.93  E-value: 2.97e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGENLIvKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPP---HKRDIG 86
Cdd:PRK09700   5 YISMAGIGKSFGPVHAL-KSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHklaAQLGIG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 MVFQNYALFPHMTVAENL---AFPL-TVRGLSKTDVSERVKRVLSM-------VQLDAFAqrypAQLSGGQQQRVALARA 155
Cdd:PRK09700  84 IIYQELSVIDELTVLENLyigRHLTkKVCGVNIIDWREMRVRAAMMllrvglkVDLDEKV----ANLSISHKQMLEIAKT 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 156 LVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQG 218
Cdd:PRK09700 160 LMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDRYTVMKDG 221
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 10-232 4.03e-22

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 97.59  E-value: 4.03e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   10 LVSFRGVQKSYDGenliVKDLN---LDIRKGEFLTLLGPSGSGKTTSLMMLAGF--ETPTAGEILLAGRSInnVPPHKRD 84
Cdd:TIGR02633   1 LLEMKGIVKTFGG----VKALDgidLEVRPGECVGLCGENGAGKSTLMKILSGVypHGTWDGEIYWSGSPL--KASNIRD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   85 -----IGMVFQNYALFPHMTVAEN--LAFPLTVRG--LSKTDVSERVKRVLSMVQLDAFAQRYP-AQLSGGQQQRVALAR 154
Cdd:TIGR02633  75 teragIVIIHQELTLVPELSVAENifLGNEITLPGgrMAYNAMYLRAKNLLRELQLDADNVTRPvGDYGGGQQQLVEIAK 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004  155 ALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEE 232
Cdd:TIGR02633 155 ALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQHVATKDMSTMSED 231
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 33-240 4.08e-22

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 94.01  E-value: 4.08e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  33 DIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSInnvpphkrdigmvfqnyALFPHMTVAEnlaFPLTVRG 112
Cdd:cd03237   21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTV-----------------SYKPQYIKAD---YEGTVRD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 113 L--SKTD----VSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKH 186
Cdd:cd03237   81 LlsSITKdfytHPYFKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRR 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 187 LHQRLGVTVVYVTHDQGEALTMSDRVAVF--HQGEIQQIAPPRTLyEEPKNTFVAN 240
Cdd:cd03237  161 FAENNEKTAFVVEHDIIMIDYLADRLIVFegEPSVNGVANPPQSL-RSGMNRFLKN 215
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 28-220 3.72e-21

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 94.73  E-value: 3.72e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  28 KDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKR-DIGMVF-----QNYALFPHMTVA 101
Cdd:PRK15439 280 RNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQRlARGLVYlpedrQSSGLYLDAPLA 359

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 102 ENLA------FPLTVRGLSKTDVSERVKRVLSMVQLDAfaqRYPAQ-LSGGQQQRVALARALVFEPQLVLMDEPLGALDK 174
Cdd:PRK15439 360 WNVCalthnrRGFWIKPARENAVLERYRRALNIKFNHA---EQAARtLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDV 436

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 657054004 175 QLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:PRK15439 437 SARNDIYQLIRSIAAQ-NVAVLFISSDLEEIEQMADRVLVMHQGEI 481
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 26-234 3.84e-21

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 91.30  E-value: 3.84e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETP----TAGEILLAGRSINNVPPHKRDIGMVFQN--YALFPHMT 99
Cdd:PRK10418  18 LVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAgvrqTAGRVLLDGKPVAPCALRGRKIATIMQNprSAFNPLHT 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 100 VAENLAFPLTVRGlsKTDVSERVKRVLSMVQLD---AFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQL 176
Cdd:PRK10418  98 MHTHARETCLALG--KPADDATLTAALEAVGLEnaaRVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLDVVA 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 177 REHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPK 234
Cdd:PRK10418 176 QARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPK 233
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 10-217 4.26e-21

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 91.33  E-value: 4.26e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEIllagrsinnVPPHKRDIGMVF 89
Cdd:PRK09544   4 LVSLENVSVSF-GQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI---------KRNGKLRIGYVP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 QNYALFPHMtvaenlafPLTVR-------GLSKTDVSERVKRVLSMVQLDAFAQRypaqLSGGQQQRVALARALVFEPQL 162
Cdd:PRK09544  74 QKLYLDTTL--------PLTVNrflrlrpGTKKEDILPALKRVQAGHLIDAPMQK----LSGGETQRVLLARALLNRPQL 141

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 163 VLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQ 217
Cdd:PRK09544 142 LVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEVLCLNH 196
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 11-223 5.69e-21

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 94.27  E-value: 5.69e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGR--SINNVPPHKRDIGMV 88
Cdd:PRK10522 323 LELRNVTFAYQDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKpvTAEQPEDYRKLFSAV 402

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQNYALFPHMTVAENL-AFPLTVRG-LSKTDVSERVK----RVLSMvqldafaqrypaQLSGGQQQRVALARALVFEPQL 162
Cdd:PRK10522 403 FTDFHLFDQLLGPEGKpANPALVEKwLERLKMAHKLEledgRISNL------------KLSKGQKKRLALLLALAEERDI 470

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657054004 163 VLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQgEALTMSDRVAVFHQGEIQQI 223
Cdd:PRK10522 471 LLLDEWAADQDPHFRREFYQVLLPLLQEMGKTIFAISHDD-HYFIHADRLLEMRNGQLSEL 530
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 16-231 8.40e-21

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 93.71  E-value: 8.40e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   16 VQKSYDGENlIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFET--PTAGEIL----------------LAGRS--- 74
Cdd:TIGR03269   6 LTKKFDGKE-VLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQyePTSGRIIyhvalcekcgyverpsKVGEPcpv 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   75 ------------INNVPPHKRD----IGMVFQ-NYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQR 137
Cdd:TIGR03269  85 cggtlepeevdfWNLSDKLRRRirkrIAIMLQrTFALYGDDTVLDNVLEALEEIGYEGKEAVGRAVDLIEMVQLSHRITH 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  138 YPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQ 217
Cdd:TIGR03269 165 IARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKAIWLEN 244

                         250
                  ....*....|....
gi 657054004  218 GEIQQIAPPRTLYE 231
Cdd:TIGR03269 245 GEIKEEGTPDEVVA 258
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
12-218 1.98e-20

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 92.28  E-value: 1.98e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  12 SFRGVQKSYDGenliVK---DLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSInnVPPHKRD---- 84
Cdd:PRK11288   6 SFDGIGKTFPG----VKaldDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEM--RFASTTAalaa 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 -IGMVFQNYALFPHMTVAENL---AFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEP 160
Cdd:PRK11288  80 gVAIIYQELHLVPEMTVAENLylgQLPHKGGIVNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNA 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 161 QLVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQG 218
Cdd:PRK11288 160 RVIAFDEPTSSLSAREIEQLFRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDG 216
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
10-220 2.34e-20

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 92.33  E-value: 2.34e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGM 87
Cdd:PRK13657 334 AVEFDDVSFSYDNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRAslRRNIAV 413

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFpHMTVAENLAfpltvrgLSKTDVS-ERVKRVLSMVQLDAFAQRYPA-----------QLSGGQQQRVALARA 155
Cdd:PRK13657 414 VFQDAGLF-NRSIEDNIR-------VGRPDATdEEMRAAAERAQAHDFIERKPDgydtvvgergrQLSGGERQRLAIARA 485

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 156 LVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQrlGVTVVYVTHdQGEALTMSDRVAVFHQGEI 220
Cdd:PRK13657 486 LLKDPPILILDEATSALDVETEAKVKAALDELMK--GRTTFIIAH-RLSTVRNADRILVFDNGRV 547
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
11-220 3.65e-20

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 92.09  E-value: 3.65e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTT--SLMMlaGFETPTAGEILLAGRSINNVpPH---KRDI 85
Cdd:PRK10790 341 IDIDNVSFAYRDDNLVLQNINLSVPSRGFVALVGHTGSGKSTlaSLLM--GYYPLTEGEIRLDGRPLSSL-SHsvlRQGV 417

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 GMVFQNYALfphmtVAENLAFPLTV-RGLSKtdvsERVKRVLSMVQLDAFAQRYPA-----------QLSGGQQQRVALA 153
Cdd:PRK10790 418 AMVQQDPVV-----LADTFLANVTLgRDISE----EQVWQALETVQLAELARSLPDglytplgeqgnNLSVGQKQLLALA 488

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 657054004 154 RALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRlgVTVVYVTHdQGEALTMSDRVAVFHQGEI 220
Cdd:PRK10790 489 RVLVQTPQILILDEATANIDSGTEQAIQQALAAVREH--TTLVVIAH-RLSTIVEADTILVLHRGQA 552
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 10-219 6.30e-20

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 90.76  E-value: 6.30e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGenliVKDLN---LDIRKGEFLTLLGPSGSGKTTSLMMLAG------FEtptaGEILLAGRSInnVPP 80
Cdd:PRK13549   5 LLEMKNITKTFGG----VKALDnvsLKVRAGEIVSLCGENGAGKSTLMKVLSGvyphgtYE----GEIIFEGEEL--QAS 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  81 HKRD-----IGMVFQNYALFPHMTVAEN--LAFPLTVRGLSKTD-VSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVAL 152
Cdd:PRK13549  75 NIRDteragIAIIHQELALVKELSVLENifLGNEITPGGIMDYDaMYLRAQKLLAQLKLDINPATPVGNLGLGQQQLVEI 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 657054004 153 ARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGE 219
Cdd:PRK13549 155 AKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGR 220
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 1-221 1.00e-19

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 91.23  E-value: 1.00e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004     1 MSEVDSNDVLvSFRGVQKSYDGENLIVKD-LNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSI-NNV 78
Cdd:TIGR01257 1929 ISGGNKTDIL-RLNELTKVYSGTSSPAVDrLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSIlTNI 2007

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    79 PPHKRDIGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVF 158
Cdd:TIGR01257 2008 SDVHQNMGYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIG 2087

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004   159 EPQLVLMDEPLGALDKQLREHMQMEIKHLhQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQ 221
Cdd:TIGR01257 2088 CPPLVLLDEPTTGMDPQARRMLWNTIVSI-IREGRAVVLTSHSMEECEALCTRLAIMVKGAFQ 2149
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
1-229 1.19e-19

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 87.54  E-value: 1.19e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   1 MSEVDSNDVLVSFRGVQKSYDGENLIvKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN--NV 78
Cdd:PRK10575   2 QEYTNHSDTTFALRNVSFRVPGRTLL-HPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLEswSS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  79 PPHKRDIGMVFQNYALFPHMTVAENLA---FPL--TVRGLSKTDvSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALA 153
Cdd:PRK10575  81 KAFARKVAYLPQQLPAAEGMTVRELVAigrYPWhgALGRFGAAD-REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIA 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 154 RALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTL 229
Cdd:PRK10575 160 MLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEL 235
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 13-201 1.67e-19

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 89.74  E-value: 1.67e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  13 FRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEIllagrsinNVPPHKRdIGMVFQNY 92
Cdd:COG0488    1 LENLSKSF-GGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEV--------SIPKGLR-IGYLPQEP 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  93 ALFPHMTVAENLAFPLTVRG---------LSKTDVSE-----------------------RVKRVLSMVQLDAFAQRYP- 139
Cdd:COG0488   71 PLDDDLTVLDTVLDGDAELRaleaeleelEAKLAEPDedlerlaelqeefealggweaeaRAEEILSGLGFPEEDLDRPv 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 140 AQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQ----LREhmqmeikHLHQRLGvTVVYVTHD 201
Cdd:COG0488  151 SELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLEsiewLEE-------FLKNYPG-TVLVVSHD 208
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
22-229 2.24e-19

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 86.58  E-value: 2.24e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGMVFQNYALFPHMT 99
Cdd:PRK10253  18 GKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEvaRRIGLLAQNATTPGDIT 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 100 VAENLAF------PLTVRgLSKTDvSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALD 173
Cdd:PRK10253  98 VQELVARgryphqPLFTR-WRKED-EEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLD 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 174 KQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTL 229
Cdd:PRK10253 176 ISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEI 231
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 26-219 2.66e-19

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 86.83  E-value: 2.66e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRsinnvpphkrdIGMVFQNYALFPHmTVAENLA 105
Cdd:cd03291   52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR-----------ISFSSQFSWIMPG-TIKENII 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 106 FpltvrGLSKTDVseRVKRVLSMVQLDAFAQRYPAQ-----------LSGGQQQRVALARALVFEPQLVLMDEPLGALD- 173
Cdd:cd03291  120 F-----GVSYDEY--RYKSVVKACQLEEDITKFPEKdntvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFGYLDv 192

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 657054004 174 ---KQLREHMQMEIKHLHQRLGVTvvyvthDQGEALTMSDRVAVFHQGE 219
Cdd:cd03291  193 fteKEIFESCVCKLMANKTRILVT------SKMEHLKKADKILILHEGS 235
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 10-289 3.13e-19

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 88.91  E-value: 3.13e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGenliVKDLN---LDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN-NVPPHKRD- 84
Cdd:PRK10762   4 LLQLKGIDKAFPG----VKALSgaaLNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTfNGPKSSQEa 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 -IGMVFQNYALFPHMTVAENL----AFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFE 159
Cdd:PRK10762  80 gIGIIHQELNLIPQLTIAENIflgrEFVNRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 160 PQLVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEiqqiapprtlyeepkntfva 239
Cdd:PRK10762 160 SKVIIMDEPTDALTDTETESLFRVIRELKSQ-GRGIVYISHRLKEIFEICDDVTVFRDGQ-------------------- 218

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 657054004 240 nFIGEnnrlngRLHSHTGERCVVELARGEKVEALAVNVGQIGGPVTLSVR 289
Cdd:PRK10762 219 -FIAE------REVADLTEDSLIEMMVGRKLEDQYPRLDKAPGEVRLKVD 261
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 6-221 4.75e-19

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 88.20  E-value: 4.75e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   6 SNDVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAgrsinnvppHKRDI 85
Cdd:COG0488  311 LGKKVLELEGLSKSY-GDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLG---------ETVKI 380

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  86 GMVFQNYALF-PHMTVAENLAfpLTVRGLSKTDVSERVKRVLsmvqldaF----AQRYPAQLSGGQQQRVALARALVFEP 160
Cdd:COG0488  381 GYFDQHQEELdPDKTVLDELR--DGAPGGTEQEVRGYLGRFL-------FsgddAFKPVGVLSGGEKARLALAKLLLSPP 451

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 161 QLVLMDEPLGALDkqlrehMQM-EIkhLHQRL----GvTVVYVTHDQG--EALTmsDRVAVFHQGEIQ 221
Cdd:COG0488  452 NVLLLDEPTNHLD------IETlEA--LEEALddfpG-TVLLVSHDRYflDRVA--TRILEFEDGGVR 508
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 27-220 7.90e-19

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 87.75  E-value: 7.90e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--------------KRDiGMVFQny 92
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQdglangivyisedrKRD-GLVLG-- 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  93 alfphMTVAENLAfpLT-VRGLSKTDVSERVKRVLSMVQ--LDAFAQRYPAQ------LSGGQQQRVALARALVFEPQLV 163
Cdd:PRK10762 345 -----MSVKENMS--LTaLRYFSRAGGSLKHADEQQAVSdfIRLFNIKTPSMeqaiglLSGGNQQKVAIARGLMTRPKVL 417

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 164 LMDEPLGALDKQLREhmqmEIKHLHQRL---GVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:PRK10762 418 ILDEPTRGVDVGAKK----EIYQLINQFkaeGLSIILVSSEMPEVLGMSDRILVMHEGRI 473
NHLM_micro_ABC1 TIGR03796
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ...
 26-222 1.34e-18

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274788 [Multi-domain]  Cd Length: 710  Bit Score: 87.31  E-value: 1.34e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGMVFQNYALFpHMTVAEN 103
Cdd:TIGR03796 494 LIENFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLYQPWSGEILFDGIPREEIPREvlANSVAMVDQDIFLF-EGTVRDN 572

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  104 LAfpLTVRGLSKTDVSERVK------RVLSMV-QLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQL 176
Cdd:TIGR03796 573 LT--LWDPTIPDADLVRACKdaaihdVITSRPgGYDAELAEGGANLSGGQRQRLEIARALVRNPSILILDEATSALDPET 650

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 657054004  177 rEHMQMEikHLHQRlGVTVVYVTHdQGEALTMSDRVAVFHQGEIQQ 222
Cdd:TIGR03796 651 -EKIIDD--NLRRR-GCTCIIVAH-RLSTIRDCDEIIVLERGKVVQ 691
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 27-221 2.27e-18

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 86.42  E-value: 2.27e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAG-FETPTAGEILLAGRSINNVPPHK---RDIGMVFQN---YALFPHMT 99
Cdd:TIGR02633 276 VDDVSFSLRRGEILGVAGLVGAGRTELVQALFGaYPGKFEGNVFINGKPVDIRNPAQairAGIAMVPEDrkrHGIVPILG 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  100 VAENLAFPLTVR--GLSKTDVSERVKRVLSMVQ---LDAFAQRYP-AQLSGGQQQRVALARALVFEPQLVLMDEPLGALD 173
Cdd:TIGR02633 356 VGKNITLSVLKSfcFKMRIDAAAELQIIGSAIQrlkVKTASPFLPiGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVD 435

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 657054004  174 KQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQ 221
Cdd:TIGR02633 436 VGAKYEIYKLINQLAQE-GVAIIVVSSELAEVLGLSDRVLVIGEGKLK 482
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 11-202 2.85e-18

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 80.57  E-value: 2.85e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGeNLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLagrsinnvpPHKRDIGmvfq 90
Cdd:cd03221    1 IELENLSKTYGG-KLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTW---------GSTVKIG---- 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 nyalfphmtvaenlafpltvrglsktdvservkrvlsmvqldafaqrYPAQLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:cd03221   67 -----------------------------------------------YFEQLSGGEKMRLALAKLLLENPNLLLLDEPTN 99

                        170       180       190
                 ....*....|....*....|....*....|..
gi 657054004 171 ALDKQLREHMQMEIKHLHQrlgvTVVYVTHDQ 202
Cdd:cd03221  100 HLDLESIEALEEALKEYPG----TVILVSHDR 127
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
11-173 2.87e-18

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 86.23  E-value: 2.87e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDG-ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINN--VPPHKRDIGM 87
Cdd:PRK11176 342 IEFRNVTFTYPGkEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDytLASLRNQVAL 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFpHMTVAENLAFPLTVRgLSKTDVSERVKRVLSM-------VQLDAFAQRYPAQLSGGQQQRVALARALVFEP 160
Cdd:PRK11176 422 VSQNVHLF-NDTIANNIAYARTEQ-YSREQIEEAARMAYAMdfinkmdNGLDTVIGENGVLLSGGQRQRIAIARALLRDS 499

                        170
                 ....*....|...
gi 657054004 161 QLVLMDEPLGALD 173
Cdd:PRK11176 500 PILILDEATSALD 512
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
2-240 4.26e-18

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 85.63  E-value: 4.26e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   2 SEVDSNDVLVSFRGVQKSYDGENLIVKdlNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRsINNVPPH 81
Cdd:PRK13409 332 RDESERETLVEYPDLTKKLGDFSLEVE--GGEIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELK-ISYKPQY 408

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  82 -KRDigmvfqnyalfPHMTVAENLAFPLTVRGLS--KTDVSERvkrvlsmVQLDAFAQRYPAQLSGGQQQRVALARALVF 158
Cdd:PRK13409 409 iKPD-----------YDGTVEDLLRSITDDLGSSyyKSEIIKP-------LQLERLLDKNVKDLSGGELQRVAIAACLSR 470

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 159 EPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDqgeaLTM----SDRVAVFhQGE--IQQIAPPRTLYEE 232
Cdd:PRK13409 471 DADLYLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHD----IYMidyiSDRLMVF-EGEpgKHGHASGPMDMRE 545


                 ....*...
gi 657054004 233 PKNTFVAN 240
Cdd:PRK13409 546 GMNRFLKE 553
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 11-200 6.61e-18

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 80.28  E-value: 6.61e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLagrsinnvpPHKRDIGMVFQ 90
Cdd:cd03223    1 IELENLSLATPDGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGM---------PEGEDLLFLPQ 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 NyALFPHMTVAENLAFPLtvrglsktdvsERVkrvlsmvqldafaqrypaqLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:cd03223   72 R-PYLPLGTLREQLIYPW-----------DDV-------------------LSGGEQQRLAFARLLLHKPKFVFLDEATS 120

                        170       180       190
                 ....*....|....*....|....*....|
gi 657054004 171 ALDKQlrehMQMEIKHLHQRLGVTVVYVTH 200
Cdd:cd03223  121 ALDEE----SEDRLYQLLKELGITVISVGH 146
PLN03211 PLN03211
ABC transporter G-25; Provisional
 37-218 7.18e-18

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 84.93  E-value: 7.18e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  37 GEFLTLLGPSGSGKTTSLMMLAG--FETPTAGEILLAGRSINNvpPHKRDIGMVFQNYALFPHMTVAENLAF------PL 108
Cdd:PLN03211  94 GEILAVLGPSGSGKSTLLNALAGriQGNNFTGTILANNRKPTK--QILKRTGFVTQDDILYPHLTVRETLVFcsllrlPK 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 109 TVRGLSKTDVSERVKRVLSMVQLD--AFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKH 186
Cdd:PLN03211 172 SLTKQEKILVAESVISELGLTKCEntIIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLGS 251

                        170       180       190
                 ....*....|....*....|....*....|...
gi 657054004 187 LHQRlGVTVVYVTHD-QGEALTMSDRVAVFHQG 218
Cdd:PLN03211 252 LAQK-GKTIVTSMHQpSSRVYQMFDSVLVLSEG 283
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 34-237 8.48e-18

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 83.25  E-value: 8.48e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  34 IRKGEFLTLLGPSGSGKTTSLMMLAGF-ETP---TAGEILLAGRSINNVPPHKR------DIGMVFQN--YALFPHMTVA 101
Cdd:PRK11022  30 VKQGEVVGIVGESGSGKSVSSLAIMGLiDYPgrvMAEKLEFNGQDLQRISEKERrnlvgaEVAMIFQDpmTSLNPCYTVG 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 102 ENLAFPLTV-RGLSKTDVSERVKRVLSMVQLDAFAQR---YPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLR 177
Cdd:PRK11022 110 FQIMEAIKVhQGGNKKTRRQRAIDLLNQVGIPDPASRldvYPHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQ 189

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 178 EHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTF 237
Cdd:PRK11022 190 AQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRAPRHPY 249
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
27-220 1.42e-17

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 84.41  E-value: 1.42e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINnvpPH----KRDIGMVFQNYALFPHMTVAE 102
Cdd:NF033858 282 VDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVD---AGdiatRRRVGYMSQAFSLYGELTVRQ 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 103 NLAfpLTVR--GLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLR--- 177
Cdd:NF033858 359 NLE--LHARlfHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARdmf 436

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 657054004 178 -EHMQmeikHLHQRLGVTVVYVTHDQGEALTmSDRVAVFHQGEI 220
Cdd:NF033858 437 wRLLI----ELSREDGVTIFISTHFMNEAER-CDRISLMHAGRV 475
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 34-200 3.14e-17

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 83.17  E-value: 3.14e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   34 IRKGEFLTLLGPSGSGKTTSLMMLAGFETP---TAGEILLAGRSINNVPPHKRDiGMVFQNYALFPHMTVAENLAFPLTV 110
Cdd:TIGR00955  48 AKPGELLAVMGSSGAGKTTLMNALAFRSPKgvkGSGSVLLNGMPIDAKEMRAIS-AYVQQDDLFIPTLTVREHLMFQAHL 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  111 R---GLSKTDVSERVKRVLSMVQLDAFAQR---YPAQ---LSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQ 181
Cdd:TIGR00955 127 RmprRVTKKEKRERVDEVLQALGLRKCANTrigVPGRvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVV 206

                         170
                  ....*....|....*....
gi 657054004  182 MEIKHLHQRlGVTVVYVTH 200
Cdd:TIGR00955 207 QVLKGLAQK-GKTIICTIH 224
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 2-219 1.03e-16

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 81.37  E-value: 1.03e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   2 SEVDSNDVLVSFRGVQKSYDGENLIVKDLnlDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRsINNVPPH 81
Cdd:COG1245  333 RREKEEETLVEYPDLTKSYGGFSLEVEGG--EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLK-ISYKPQY 409

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  82 -KRDIgmvfqnyalfpHMTVAENLAFPLTVRGLSKTDVSERVKRvlsmVQLDAFAQRYPAQLSGGQQQRVALARALVFEP 160
Cdd:COG1245  410 iSPDY-----------DGTVEEFLRSANTDDFGSSYYKTEIIKP----LGLEKLLDKNVKDLSGGELQRVAIAACLSRDA 474

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 161 QLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDqgeaLTM----SDRVAVFHqGE 219
Cdd:COG1245  475 DLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDHD----IYLidyiSDRLMVFE-GE 532
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 30-218 1.27e-16

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 78.44  E-value: 1.27e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  30 LNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFeTPTAGEILLAGRSINNVPPHK--RDIGMVFQNYALFPHMTVAENLAFP 107
Cdd:PRK03695  15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPLEAWSAAElaRHRAYLSQQQTPPFAMPVFQYLTLH 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 108 LTVrGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALA-------RALVFEPQLVLMDEPLGALDKQLREHM 180
Cdd:PRK03695  94 QPD-KTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAavvlqvwPDINPAGQLLLLDEPMNSLDVAQQAAL 172

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 657054004 181 QMEIKHLHQrLGVTVVYVTHDQGEALTMSDRVAVFHQG 218
Cdd:PRK03695 173 DRLLSELCQ-QGIAVVMSSHDLNHTLRHADRVWLLKQG 209
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
27-223 1.80e-16

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 80.60  E-value: 1.80e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH---KRDIGMVFQNY---ALFPHMTV 100
Cdd:PRK09700 279 VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLdavKKGMAYITESRrdnGFFPNFSI 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 101 AENLAFPLTVR--------GLsktdVSERVKRVLSMVQLDAFAQRYPA------QLSGGQQQRVALARALVFEPQLVLMD 166
Cdd:PRK09700 359 AQNMAISRSLKdggykgamGL----FHEVDEQRTAENQRELLALKCHSvnqnitELSGGNQQKVLISKWLCCCPEVIIFD 434

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 167 EPLGALDKQLREhmqmEIKHLHQRL---GVTVVYVTHDQGEALTMSDRVAVFHQGEIQQI 223
Cdd:PRK09700 435 EPTRGIDVGAKA----EIYKVMRQLaddGKVILMVSSELPEIITVCDRIAVFCEGRLTQI 490
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 26-221 2.86e-16

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 79.97  E-value: 2.86e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAG-FETPTAGEILLAGRSINNVPPH---KRDIGMVFQN---YALFPHM 98
Cdd:PRK13549 277 RVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGaYPGRWEGEIFIDGKPVKIRNPQqaiAQGIAMVPEDrkrDGIVPVM 356

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  99 TVAENLAFPLTVR--GLSKTDVSERVKRVLSMVQ---LDAFAQRYP-AQLSGGQQQRVALARALVFEPQLVLMDEPLGAL 172
Cdd:PRK13549 357 GVGKNITLAALDRftGGSRIDDAAELKTILESIQrlkVKTASPELAiARLSGGNQQKAVLAKCLLLNPKILILDEPTRGI 436

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 657054004 173 DKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQ 221
Cdd:PRK13549 437 DVGAKYEIYKLINQLVQQ-GVAIIVISSELPEVLGLSDRVLVMHEGKLK 484
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 14-219 4.52e-16

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 79.39  E-value: 4.52e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYDGenliVKDL---NLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN---NVPPHKRDIGM 87
Cdd:PRK10982   2 SNISKSFPG----VKALdnvNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDfksSKEALENGISM 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNYALFPHMTVAENL---AFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVL 164
Cdd:PRK10982  78 VHQELNLVLQRSVMDNMwlgRYPTKGMFVDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVI 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 165 MDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGE 219
Cdd:PRK10982 158 MDEPTSSLTEKEVNHLFTIIRKLKER-GCGIVYISHKMEEIFQLCDEITILRDGQ 211
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 26-202 4.66e-16

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 76.15  E-value: 4.66e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFE--TPTAGEILLAGRSINNVPPhkrdigmvfqnyalfphmtVAEN 103
Cdd:COG2401   45 VLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDVPDNQFGREAS-------------------LIDA 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 104 LAfpltvrglSKTDVSErVKRVLSMVQL-DAFA-QRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQ 181
Cdd:COG2401  106 IG--------RKGDFKD-AVELLNAVGLsDAVLwLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVA 176

                        170       180
                 ....*....|....*....|.
gi 657054004 182 MEIKHLHQRLGVTVVYVTHDQ 202
Cdd:COG2401  177 RNLQKLARRAGITLVVATHHY 197
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 23-210 5.53e-16

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 75.76  E-value: 5.53e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  23 ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN-NVPPHKRDIGMVFQNYALFPHMTVA 101
Cdd:PRK13540  13 DQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKkDLCTYQKQLCFVGHRSGINPYLTLR 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 102 ENLAFPLTvrgLSKTDVSerVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQ 181
Cdd:PRK13540  93 ENCLYDIH---FSPGAVG--ITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTII 167

                        170       180
                 ....*....|....*....|....*....
gi 657054004 182 MEIKHlHQRLGVTVVYVTHdQGEALTMSD 210
Cdd:PRK13540 168 TKIQE-HRAKGGAVLLTSH-QDLPLNKAD 194
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 26-220 2.03e-15

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 74.22  E-value: 2.03e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAG----FETPTaGEILLAGRSIN-NVPPHKRDIGMVFQNYALFPHMTV 100
Cdd:cd03233   22 ILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANrtegNVSVE-GDIHYNGIPYKeFAEKYPGEIIYVSEEDVHFPTLTV 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 101 AENLAFPLTVRGlsktdvSERVKRVlsmvqldafaqrypaqlSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHM 180
Cdd:cd03233  101 RETLDFALRCKG------NEFVRGI-----------------SGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTALEI 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 657054004 181 QMEIKHLHQRLG-VTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:cd03233  158 LKCIRTMADVLKtTTFVSLYQASDEIYDLFDKVLVLYEGRQ 198
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
23-233 3.13e-15

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 77.06  E-value: 3.13e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  23 ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGMVFQNYALFPHmTV 100
Cdd:PRK10789 327 DHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDswRSRLAVVSQTPFLFSD-TV 405

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 101 AENLAfpltvrgLSKTDVS----ERVKRvLSMVQLDAF--AQRYPAQ-------LSGGQQQRVALARALVFEPQLVLMDE 167
Cdd:PRK10789 406 ANNIA-------LGRPDATqqeiEHVAR-LASVHDDILrlPQGYDTEvgergvmLSGGQKQRISIARALLLNAEILILDD 477

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 168 PLGALDKQlREHmqmEIKH-LHQ-RLGVTVVYVTHdQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEP 233
Cdd:PRK10789 478 ALSAVDGR-TEH---QILHnLRQwGEGRTVIISAH-RLSALTEASEILVMQHGHIAQRGNHDQLAQQS 540
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 26-218 3.53e-15

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 77.26  E-value: 3.53e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRsinnvpphkrdIGMVFQNYALFPHmTVAENLA 105
Cdd:TIGR01271  441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGR-----------ISFSPQTSWIMPG-TIKDNII 508

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   106 FpltvrGLSKTDVseRVKRVLSMVQLDAFAQRYPAQ-----------LSGGQQQRVALARALVFEPQLVLMDEPLGALD- 173
Cdd:TIGR01271  509 F-----GLSYDEY--RYTSVIKACQLEEDIALFPEKdktvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFTHLDv 581

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 657054004   174 ---KQLREHMQMEIKHLHQRLGVTvvyvthDQGEALTMSDRVAVFHQG 218
Cdd:TIGR01271  582 vteKEIFESCLCKLMSNKTRILVT------SKLEHLKKADKILLLHEG 623
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 17-216 4.56e-15

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 76.99  E-value: 4.56e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   17 QKSYDGENLIVKDLNldirkgEFlTLLGPSGSGKTTSLMmlagfetPTAGEILLAGRSI--NNVPPHKRDIGMVFQNYAL 94
Cdd:PTZ00265 1242 YQGDEEQNVGMKNVN------EF-SLTKEGGSGEDSTVF-------KNSGKILLDGVDIcdYNLKDLRNLFSIVSQEPML 1307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   95 FpHMTVAENLAFpltvrglSKTDVS-ERVKRVLSMVQLDAFAQRYPAQ-----------LSGGQQQRVALARALVFEPQL 162
Cdd:PTZ00265 1308 F-NMSIYENIKF-------GKEDATrEDVKRACKFAAIDEFIESLPNKydtnvgpygksLSGGQKQRIAIARALLREPKI 1379

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 657054004  163 VLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHdQGEALTMSDRVAVFH 216
Cdd:PTZ00265 1380 LLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAH-RIASIKRSDKIVVFN 1432
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 34-175 6.66e-15

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 72.28  E-value: 6.66e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  34 IRKGEFLTLLGPSGSGKTTSLMMLAGFETP--TAGEILLAGRSINnvPPHKRDIGMVFQNYALFPHMTVAENLAFPLTVR 111
Cdd:cd03232   30 VKPGTLTALMGESGAGKTTLLDVLAGRKTAgvITGEILINGRPLD--KNFQRSTGYVEQQDVHSPNLTVREALRFSALLR 107

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 657054004 112 GLSktdVSERvkrvlsmvqldafaqrypaqlsggqqQRVALARALVFEPQLVLMDEPLGALDKQ 175
Cdd:cd03232  108 GLS---VEQR--------------------------KRLTIGVELAAKPSILFLDEPTSGLDSQ 142
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 12-201 9.70e-15

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 75.36  E-value: 9.70e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   12 SFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAgrsinnvPPHKrdIGMVFQN 91
Cdd:TIGR03719   6 TMNRVSKVVPPKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQ-------PGIK--VGYLPQE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   92 YALFPHMTVAEN--LAFPLTVRGLSKTD-VSER-----------------------------VKRVLSMVqldAFAQRYP 139
Cdd:TIGR03719  77 PQLDPTKTVRENveEGVAEIKDALDRFNeISAKyaepdadfdklaaeqaelqeiidaadawdLDSQLEIA---MDALRCP 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004  140 ------AQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQmeiKHLHQRLGvTVVYVTHD 201
Cdd:TIGR03719 154 pwdadvTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLE---RHLQEYPG-TVVAVTHD 217
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 22-173 1.26e-14

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 72.75  E-value: 1.26e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  22 GENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFE--TPTAGEILLAGRSINNVPPHKRD---IGMVFQNYALFP 96
Cdd:CHL00131  18 NENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPayKILEGDILFKGESILDLEPEERAhlgIFLAFQYPIEIP 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  97 HMTVAENLAFPLTVR----GLSKTD---VSERVKRVLSMVQLDA-FAQRYPAQ-LSGGQQQRVALARALVFEPQLVLMDE 167
Cdd:CHL00131  98 GVSNADFLRLAYNSKrkfqGLPELDpleFLEIINEKLKLVGMDPsFLSRNVNEgFSGGEKKRNEILQMALLDSELAILDE 177


                 ....*.
gi 657054004 168 PLGALD 173
Cdd:CHL00131 178 TDSGLD 183
TOBE_2 pfam08402
TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the ...
 286-363 1.46e-14

TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the C-terminal strand of each domain is supplied by the partner. Probably involved in the recognition of small ligands such as molybdenum and sulphate. Found in ABC transporters immediately after the ATPase domain. In this family a strong RPE motif is found at the presumed N-terminus of the domain.


Pssm-ID: 462465 [Multi-domain]  Cd Length: 73  Bit Score: 68.03  E-value: 1.46e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004  286 LSVRPERVSLNGssesCSNRFSGRVAEFIYLGDHVRVRLEVCGKADFFVKQPIAELDPaLTVGDVVPIGWQVEHVRAL 363
Cdd:pfam08402   1 LAIRPEKIRLAA----AANGLSGTVTDVEYLGDHTRYHVELAGGEELVVRVPNAHARP-PAPGDRVGLGWDPEDAHVL 73
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 8-173 2.04e-14

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 74.20  E-value: 2.04e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    8 DVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLaGRSInnvpphkrDIGM 87
Cdd:TIGR03719 320 DKVIEAENLTKAF-GDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETV--------KLAY 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   88 VFQNY-ALFPHMTVAENLAFPLTVRGLSKTDVSERvkrvlsmVQLDAFA------QRYPAQLSGGQQQRVALARALVFEP 160
Cdd:TIGR03719 390 VDQSRdALDPNKTVWEEISGGLDIIKLGKREIPSR-------AYVGRFNfkgsdqQKKVGQLSGGERNRVHLAKTLKSGG 462

                         170
                  ....*....|...
gi 657054004  161 QLVLMDEPLGALD 173
Cdd:TIGR03719 463 NVLLLDEPTNDLD 475
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 12-229 3.38e-14

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 73.68  E-value: 3.38e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  12 SFRGVQKSY----DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSinnVPPHKRD--- 84
Cdd:COG4615  329 ELRGVTYRYpgedGDEGFTLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQP---VTADNREayr 405

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 --IGMVFQNYALFPHMTvaenlafpltvrGLSKTDVSERVKRVLSMVQLD--------AFAQRypaQLSGGQQQRVALAR 154
Cdd:COG4615  406 qlFSAVFSDFHLFDRLL------------GLDGEADPARARELLERLELDhkvsvedgRFSTT---DLSQGQRKRLALLV 470

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 155 ALVFEPQLVLMDE------PlgaldkQLREHMQMEIKHLHQRLGVTVVYVTHDQ---GEAltmsDRVAVFHQGEIQQIAP 225
Cdd:COG4615  471 ALLEDRPILVFDEwaadqdP------EFRRVFYTELLPELKARGKTVIAISHDDryfDLA----DRVLKMDYGKLVELTG 540


                 ....
gi 657054004 226 PRTL 229
Cdd:COG4615  541 PAAL 544
hmuV PRK13547
heme ABC transporter ATP-binding protein;
24-227 1.39e-13

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 70.24  E-value: 1.39e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  24 NLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAG-FETPTA-------GEILLAGRSINNVPPHKrdigmVFQNYALF 95
Cdd:PRK13547  14 RAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGdLTGGGAprgarvtGDVTLNGEPLAAIDAPR-----LARLRAVL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  96 PHmtvAENLAFPLTVR--------------GLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARAL----- 156
Cdd:PRK13547  89 PQ---AAQPAFAFSAReivllgrypharraGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLaqlwp 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 157 ----VFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPR 227
Cdd:PRK13547 166 phdaAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPA 240
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 33-216 1.67e-13

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 67.98  E-value: 1.67e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  33 DIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINnVPPHKRDigmvfqnyalfphmtvaenlafpltvrg 112
Cdd:cd03222   21 VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGITPV-YKPQYID---------------------------- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 113 lsktdvservkrvlsmvqldafaqrypaqLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRLG 192
Cdd:cd03222   72 -----------------------------LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGK 122

                        170       180
                 ....*....|....*....|....
gi 657054004 193 VTVVYVTHDQGEALTMSDRVAVFH 216
Cdd:cd03222  123 KTALVVEHDLAVLDYLSDRIHVFE 146
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 17-178 2.86e-13

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 67.97  E-value: 2.86e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  17 QKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVppHKRDIGMVFQNYALFP 96
Cdd:PRK13541   6 QLQFNIEQKNLFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNI--AKPYCTYIGHNLGLKL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  97 HMTVAENLAFPLTVrglskTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQL 176
Cdd:PRK13541  84 EMTVFENLKFWSEI-----YNSAETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKEN 158


                 ..
gi 657054004 177 RE 178
Cdd:PRK13541 159 RD 160
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
30-173 2.96e-13

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 68.34  E-value: 2.96e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  30 LNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSiNNVPPHKRDIGMVFQNYALFPHMTVAENLAFplt 109
Cdd:PRK13543  30 LDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKT-ATRGDRSRFMAYLGHLPGLKADLSTLENLHF--- 105

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 657054004 110 VRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALD 173
Cdd:PRK13543 106 LCGLHGRRAKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLD 169
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
31-220 4.56e-13

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 69.94  E-value: 4.56e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  31 NLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSIN-NVPPHKRDIGMVF-----QNYALFPHMTVAENL 104
Cdd:PRK11288 273 SFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDiRSPRDAIRAGIMLcpedrKAEGIIPVHSVADNI 352

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 105 AfpLTVRGLSKTD---VSERVKRVLSMVQLDAFAQRYPA------QLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQ 175
Cdd:PRK11288 353 N--ISARRHHLRAgclINNRWEAENADRFIRSLNIKTPSreqlimNLSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVG 430

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 657054004 176 LREhmqmEIKHLHQRL---GVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:PRK11288 431 AKH----EIYNVIYELaaqGVAVLFVSSDLPEVLGVADRIVVMREGRI 474
PTZ00243 PTZ00243
ABC transporter; Provisional
 26-221 1.78e-12

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 69.04  E-value: 1.78e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAG-FETpTAGEILlAGRSINNVPPHkrdigmvfqnyALFPHMTVAENL 104
Cdd:PTZ00243  675 LLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSqFEI-SEGRVW-AERSIAYVPQQ-----------AWIMNATVRGNI 741

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  105 AFpltvrgLSKTDvSERVKRVLSMVQLDAFAQRYPA-----------QLSGGQQQRVALARALVFEPQLVLMDEPLGALD 173
Cdd:PTZ00243  742 LF------FDEED-AARLADAVRVSQLEADLAQLGGgleteigekgvNLSGGQKARVSLARAVYANRDVYLLDDPLSALD 814

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 657054004  174 KQLREHMQME--IKHLHqrlGVTVVYVTHdQGEALTMSDRVAVFHQGEIQ 221
Cdd:PTZ00243  815 AHVGERVVEEcfLGALA---GKTRVLATH-QVHVVPRADYVVALGDGRVE 860
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
21-233 1.95e-12

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 67.24  E-value: 1.95e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  21 DGENLIVKDLNLDIRKGEFLTLLGPSGSGKttSLMMLA--GFETP----TAGEILLAGRSINNVPPHKR------DIGMV 88
Cdd:COG4170   17 QGRVKAVDRVSLTLNEGEIRGLVGESGSGK--SLIAKAicGITKDnwhvTADRFRWNGIDLLKLSPRERrkiigrEIAMI 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  89 FQN--YALFPHMTVAENLAFPL---TVRGL---SKTDVSERVKRVLSMVQL---DAFAQRYPAQLSGGQQQRVALARALV 157
Cdd:COG4170   95 FQEpsSCLDPSAKIGDQLIEAIpswTFKGKwwqRFKWRKKRAIELLHRVGIkdhKDIMNSYPHELTEGECQKVMIAMAIA 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 158 FEPQLVLMDEPLGALDKQlrehMQMEIKHLHQRL----GVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEP 233
Cdd:COG4170  175 NQPRLLIADEPTNAMEST----TQAQIFRLLARLnqlqGTSILLISHDLESISQWADTITVLYCGQTVESGPTEQILKSP 250
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 11-232 2.18e-12

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 68.82  E-value: 2.18e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    11 VSFRGVQKSY-DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH--KRDIGM 87
Cdd:TIGR00957 1285 VEFRNYCLRYrEDLDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHdlRFKITI 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    88 VFQNYALFPHmTVAENLAfPLTvrglSKTDvsERVKRVLSMVQLDAFAQRYPAQL-----------SGGQQQRVALARAL 156
Cdd:TIGR00957 1365 IPQDPVLFSG-SLRMNLD-PFS----QYSD--EEVWWALELAHLKTFVSALPDKLdhecaeggenlSVGQRQLVCLARAL 1436

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004   157 VFEPQLVLMDEPLGALDKQLREHMQMEIKhlHQRLGVTVVYVTHDQGEALTMSdRVAVFHQGEIQQIAPPRTLYEE 232
Cdd:TIGR00957 1437 LRKTKILVLDEATAAVDLETDNLIQSTIR--TQFEDCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNLLQQ 1509
GguA NF040905
sugar ABC transporter ATP-binding protein;
14-218 2.19e-12

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 67.89  E-value: 2.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  14 RGVQKSYDGenliVK---DLNLDIRKGEFLTLLGPSGSGKTTsLM-MLAG------FEtptaGEILLAG-----RSINNv 78
Cdd:NF040905   5 RGITKTFPG----VKaldDVNLSVREGEIHALCGENGAGKST-LMkVLSGvyphgsYE----GEILFDGevcrfKDIRD- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  79 pPHKRDIGMVFQNYALFPHMTVAEN--LAFPLTVRGL-SKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARA 155
Cdd:NF040905  75 -SEALGIVIIHQELALIPYLSIAENifLGNERAKRGViDWNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKA 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004 156 LVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQG 218
Cdd:NF040905 154 LSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDG 215
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
11-168 5.12e-12

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 67.46  E-value: 5.12e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNvPPHKRDIG---- 86
Cdd:NF033858   2 ARLEGVSHRY-GKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMAD-ARHRRAVCpria 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 -MVfQ----NyaLFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRyPA-QLSGGQQQRVALARALVFEP 160
Cdd:NF033858  80 yMP-QglgkN--LYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADR-PAgKLSGGMKQKLGLCCALIHDP 155


                 ....*...
gi 657054004 161 QLVLMDEP 168
Cdd:NF033858 156 DLLILDEP 163
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 12-201 5.50e-12

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 67.07  E-value: 5.50e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  12 SFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAgrsinnvPPHKrdIGMVFQN 91
Cdd:PRK11819   8 TMNRVSKVVPPKKQILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPA-------PGIK--VGYLPQE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  92 YALFPHMTVAENlafpltvrglsktdVSERVKRVLSMV-----------------------------QLDAF-------- 134
Cdd:PRK11819  79 PQLDPEKTVREN--------------VEEGVAEVKAALdrfneiyaayaepdadfdalaaeqgelqeIIDAAdawdldsq 144

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004 135 ------AQRYP------AQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQmeiKHLHQRLGvTVVYVTHD 201
Cdd:PRK11819 145 leiamdALRCPpwdakvTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLE---QFLHDYPG-TVVAVTHD 219
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
7-230 6.85e-12

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 65.29  E-value: 6.85e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   7 NDVLVSFRGVQKSydgenliVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVpphkrdig 86
Cdd:PRK15056  10 NDVTVTWRNGHTA-------LRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQA-------- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  87 mVFQNYALFPHMTVAENLAFPLTVRGL--------------SKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVAL 152
Cdd:PRK15056  75 -LQKNLVAYVPQSEEVDWSFPVLVEDVvmmgryghmgwlrrAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 153 ARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDrVAVFHQGEIQQIAPPRTLY 230
Cdd:PRK15056 154 ARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDE-GKTMLVSTHNLGSVTEFCD-YTVMVKGTVLASGPTETTF 229
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
11-233 7.03e-12

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 65.91  E-value: 7.03e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  11 VSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSlMMLAGFETPTAGEILLAGRS-INNVPPHKRDIGMVF 89
Cdd:NF000106  14 VEVRGLVKHF-GEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRRPWRF*TwCANRRALRRTIG*HR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 Q-NYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEP 168
Cdd:NF000106  92 PvR*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEP 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 657054004 169 LGALDKQLREHMQMEIKHLhQRLGVTVVYVTHDQGEA------LTMSDRVAVFHQGEIQQIAPP---RTLYEEP 233
Cdd:NF000106 172 TTGLDPRTRNEVWDEVRSM-VRDGATVLLTTQYMEEAeqlaheLTVIDRGRVIADGKVDELKTKvggRTLQIRP 244
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 35-201 2.96e-11

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 63.15  E-value: 2.96e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  35 RKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEillagrsiNNVPPHKRDI-----GMVFQNY-------ALFPHMTVAE 102
Cdd:cd03236   24 REGQVLGLVGPNGIGKSTALKILAGKLKPNLGK--------FDDPPDWDEIldefrGSELQNYftkllegDVKVIVKPQY 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 103 NLAFPLTVRG-----LSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLR 177
Cdd:cd03236   96 VDLIPKAVKGkvgelLKKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQR 175

                        170       180
                 ....*....|....*....|....
gi 657054004 178 EHMQMEIKHLHQRlGVTVVYVTHD 201
Cdd:cd03236  176 LNAARLIRELAED-DNYVLVVEHD 198
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 35-219 3.35e-11

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 64.42  E-value: 3.35e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  35 RKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEIllagrsinNVPPHKRDIGMVFQNYALFPHMT-VAEN---------- 103
Cdd:COG1245   97 KKGKVTGILGPNGIGKSTALKILSGELKPNLGDY--------DEEPSWDEVLKRFRGTELQDYFKkLANGeikvahkpqy 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 104 -----LAFPLTVRG-LSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDkqLR 177
Cdd:COG1245  169 vdlipKVFKGTVRElLEKVDERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLD--IY 246

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 657054004 178 EHMQME--IKHLhQRLGVTVVYVTHDqgeaLT----MSDRVAVFHqGE 219
Cdd:COG1245  247 QRLNVArlIREL-AEEGKYVLVVEHD----LAildyLADYVHILY-GE 288
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 13-173 4.44e-11

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 64.74  E-value: 4.44e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    13 FRGVQKSYDGENL-IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLA----GFETPTAGEILLAGRSINNVPPHKR-DIG 86
Cdd:TIGR00956   62 FRKLKKFRDTKTFdILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIAsntdGFHIGVEGVITYDGITPEEIKKHYRgDVV 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    87 MVFQNYALFPHMTVAENLAFPLTVR-------GLSKTDVSERVKRV------LSMVQLDAFAQRYPAQLSGGQQQRVALA 153
Cdd:TIGR00956  142 YNAETDVHFPHLTVGETLDFAARCKtpqnrpdGVSREEYAKHIADVymatygLSHTRNTKVGNDFVRGVSGGERKRVSIA 221

                          170       180
                   ....*....|....*....|
gi 657054004   154 RALVFEPQLVLMDEPLGALD 173
Cdd:TIGR00956  222 EASLGGAKIQCWDNATRGLD 241
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 8-173 5.07e-11

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 63.98  E-value: 5.07e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   8 DVLVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLaGRSInnvpphkrDIGM 87
Cdd:PRK11819 322 DKVIEAENLSKSF-GDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETV--------KLAY 391

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  88 VFQNY-ALFPHMTVAENLAFPLTVRGLSKTDVSERvkrvlsmVQLDAFA------QRYPAQLSGGQQQRVALARALVFEP 160
Cdd:PRK11819 392 VDQSRdALDPNKTVWEEISGGLDIIKVGNREIPSR-------AYVGRFNfkggdqQKKVGVLSGGERNRLHLAKTLKQGG 464

                        170
                 ....*....|...
gi 657054004 161 QLVLMDEPLGALD 173
Cdd:PRK11819 465 NVLLLDEPTNDLD 477
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 34-175 8.55e-11

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 63.59  E-value: 8.55e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    34 IRKGEFLTLLGPSGSGKTTSLMMLAGFETP---TAGEILLAGRSINNvpPHKRDIGMVFQNYALFPHMTVAENLAF---- 106
Cdd:TIGR00956  786 VKPGTLTALMGASGAGKTTLLNVLAERVTTgviTGGDRLVNGRPLDS--SFQRSIGYVQQQDLHLPTSTVRESLRFsayl 863

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657054004   107 --PLTVRGLSKTDVSERVKRVLSMVQL-DAFAQRYPAQLSGGQQQRVALARALVFEPQLVL-MDEPLGALDKQ 175
Cdd:TIGR00956  864 rqPKSVSKSEKMEYVEEVIKLLEMESYaDAVVGVPGEGLNVEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQ 936
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 27-200 1.12e-10

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 60.81  E-value: 1.12e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRD------IGMVFQNYALFpHMTV 100
Cdd:cd03290   17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRsrnrysVAYAAQKPWLL-NATV 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 101 AENLAF--PLTvrglsktdvSERVKRVLSMVQLDAFAQRYP-----------AQLSGGQQQRVALARALVFEPQLVLMDE 167
Cdd:cd03290   96 EENITFgsPFN---------KQRYKAVTDACSLQPDIDLLPfgdqteigergINLSGGQRQRICVARALYQNTNIVFLDD 166

                        170       180       190
                 ....*....|....*....|....*....|....
gi 657054004 168 PLGALDKQLREH-MQMEIKHLHQRLGVTVVYVTH 200
Cdd:cd03290  167 PFSALDIHLSDHlMQEGILKFLQDDKRTLVLVTH 200
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 15-201 1.14e-10

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 62.60  E-value: 1.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  15 GVQKSYDGENLIvKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAgrsinnvppHKRDIGMVFQNYAL 94
Cdd:PRK15064 324 NLTKGFDNGPLF-KNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWS---------ENANIGYYAQDHAY 393

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  95 -FPH-MTVAENLAF-------PLTVRGL------SKTDVSERVKrvlsmvqldafaqrypaQLSGGQQQRVALARALVFE 159
Cdd:PRK15064 394 dFENdLTLFDWMSQwrqegddEQAVRGTlgrllfSQDDIKKSVK-----------------VLSGGEKGRMLFGKLMMQK 456

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 657054004 160 PQLVLMDEPlgaldkqlREHMQME-IKHLHQRLGV---TVVYVTHD 201
Cdd:PRK15064 457 PNVLVMDEP--------TNHMDMEsIESLNMALEKyegTLIFVSHD 494
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 26-200 1.61e-10

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 62.46  E-value: 1.61e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFeTPTAGEILlagrsinnVPPHKRDIGMVFQNyalfPHMTVA---E 102
Cdd:TIGR00954 467 LIESLSFEVPSGNNLLICGPNGCGKSSLFRILGEL-WPVYGGRL--------TKPAKGKLFYVPQR----PYMTLGtlrD 533

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  103 NLAFPLTVRGLSKTDVSERV-KRVLSMVQLDAFAQR---------YPAQLSGGQQQRVALARALVFEPQLVLMDEPLGAL 172
Cdd:TIGR00954 534 QIIYPDSSEDMKRRGLSDKDlEQILDNVQLTHILEReggwsavqdWMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAV 613

                         170       180
                  ....*....|....*....|....*...
gi 657054004  173 DKQlrehMQMEIKHLHQRLGVTVVYVTH 200
Cdd:TIGR00954 614 SVD----VEGYMYRLCREFGITLFSVSH 637
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 26-226 2.90e-10

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 59.35  E-value: 2.90e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHK--RDIGMVFQNYALFPHmTVAEN 103
Cdd:cd03369   23 VLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDlrSSLTIIPQDPTLFSG-TIRSN 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 104 LafpltvrglsktDVSERvkrvLSMVQLDAfAQRYPA---QLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHM 180
Cdd:cd03369  102 L------------DPFDE----YSDEEIYG-ALRVSEgglNLSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALI 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 657054004 181 QMEIKHLHQrlGVTVVYVTHDQGEALTMsDRVAVFHQGEIQQIAPP 226
Cdd:cd03369  165 QKTIREEFT--NSTILTIAHRLRTIIDY-DKILVMDAGEVKEYDHP 207
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 11-259 3.41e-10

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 61.97  E-value: 3.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   11 VSFRGVQKSYDGEN--LIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLaGRSIN----NVPPHKRD 84
Cdd:PTZ00265  383 IQFKNVRFHYDTRKdvEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIII-NDSHNlkdiNLKWWRSK 461

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   85 IGMVFQNYALFPHmTVAENLAFPL-------------------TVRGLSK------------------------------ 115
Cdd:PTZ00265  462 IGVVSQDPLLFSN-SIKNNIKYSLyslkdlealsnyynedgndSQENKNKrnscrakcagdlndmsnttdsneliemrkn 540

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  116 ------TDVSERVKRVLSMVQLDAFAQRY-------PAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQM 182
Cdd:PTZ00265  541 yqtikdSEVVDVSKKVLIHDFVSALPDKYetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQK 620

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 657054004  183 EIKHLHQRLGVTVVYVTHdQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVANFIGENNRLNGRLHSHTGER 259
Cdd:PTZ00265  621 TINNLKGNENRITIIIAH-RLSTIRYANTIFVLSNRERGSTVDVDIIGEDPTKDNKENNNKNNKDDNNNNNNNNNNK 696
PLN03130 PLN03130
ABC transporter C family member; Provisional
 21-222 6.37e-10

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 60.91  E-value: 6.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   21 DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTtSLM--MLAGFETPTAGEILLAGrSINNVPphkrDIGMVFqnyalfpHM 98
Cdd:PLN03130  627 KAERPTLSNINLDVPVGSLVAIVGSTGEGKT-SLIsaMLGELPPRSDASVVIRG-TVAYVP----QVSWIF-------NA 693

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   99 TVAENLAFPLTVRglsktdvSERVKRVLSMVQLDAFAQRYPA-----------QLSGGQQQRVALARALVFEPQLVLMDE 167
Cdd:PLN03130  694 TVRDNILFGSPFD-------PERYERAIDVTALQHDLDLLPGgdlteigergvNISGGQKQRVSMARAVYSNSDVYIFDD 766

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004  168 PLGALDKQLREhmQMEIKHLHQRL-GVTVVYVThDQGEALTMSDRVAVFHQGEIQQ 222
Cdd:PLN03130  767 PLSALDAHVGR--QVFDKCIKDELrGKTRVLVT-NQLHFLSQVDRIILVHEGMIKE 819
PLN03232 PLN03232
ABC transporter C family member; Provisional
 23-222 8.82e-10

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 60.37  E-value: 8.82e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   23 ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPphkrDIGMVFqnyalfpHMTVAE 102
Cdd:PLN03232  629 SKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAETSSVVIRGSVAYVP----QVSWIF-------NATVRE 697

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  103 NLAFPltvrglSKTDvSERVKRVLSMV----QLDAFAQRYPAQL-------SGGQQQRVALARALVFEPQLVLMDEPLGA 171
Cdd:PLN03232  698 NILFG------SDFE-SERYWRAIDVTalqhDLDLLPGRDLTEIgergvniSGGQKQRVSMARAVYSNSDIYIFDDPLSA 770

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 657054004  172 LDKQL-REHMQMEIKHLHQrlGVTVVYVThDQGEALTMSDRVAVFHQGEIQQ 222
Cdd:PLN03232  771 LDAHVaHQVFDSCMKDELK--GKTRVLVT-NQLHFLPLMDRIILVSEGMIKE 819
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 23-173 1.04e-09

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 58.26  E-value: 1.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  23 ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFE--TPTAGEILLAGRSINNVPPHKR---DIGMVFQNYALFPh 97
Cdd:PRK09580  13 DKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLELSPEDRageGIFMAFQYPVEIP- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  98 mTVAENLAFPLTVRGLSK------------TDVSERVKRVLSMVQlDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLM 165
Cdd:PRK09580  92 -GVSNQFFLQTALNAVRSyrgqepldrfdfQDLMEEKIALLKMPE-DLLTRSVNVGFSGGEKKRNDILQMAVLEPELCIL 169


                 ....*...
gi 657054004 166 DEPLGALD 173
Cdd:PRK09580 170 DESDSGLD 177
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 30-278 1.10e-09

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 60.34  E-value: 1.10e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    30 LNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGrSINNVPPHkrdigmvfqnyALFPHMTVAENLAFplt 109
Cdd:TIGR00957  657 ITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKG-SVAYVPQQ-----------AWIQNDSLRENILF--- 721

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   110 vrglSKTDVSERVKRVLSMVQLDAFAQRYPA-----------QLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLRE 178
Cdd:TIGR00957  722 ----GKALNEKYYQQVLEACALLPDLEILPSgdrteigekgvNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGK 797

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   179 HMqmeIKHLHQRLGV----TVVYVTHDQgEALTMSDRVAVFHQGEIQQIAPPRTLYEepKNTFVANFIGENNRLNGRLHS 254
Cdd:TIGR00957  798 HI---FEHVIGPEGVlknkTRILVTHGI-SYLPQVDVIIVMSGGKISEMGSYQELLQ--RDGAFAEFLRTYAPDEQQGHL 871

                          250       260
                   ....*....|....*....|....
gi 657054004   255 htgERCVVELARGEKVEALAVNVG 278
Cdd:TIGR00957  872 ---EDSWTALVSGEGKEAKLIENG 892
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 16-173 1.40e-09

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 59.58  E-value: 1.40e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  16 VQKSYDGENLiVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEIllagrsinnvppH---KRDIGMvFQNY 92
Cdd:PRK11147 325 VNYQIDGKQL-VKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRI------------HcgtKLEVAY-FDQH 390

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  93 --ALFPHMTVAENLAfpltvRGLSKTDVSERVKRVLSMVQLDAFA---QRYPAQ-LSGGQQQRVALARALVFEPQLVLMD 166
Cdd:PRK11147 391 raELDPEKTVMDNLA-----EGKQEVMVNGRPRHVLGYLQDFLFHpkrAMTPVKaLSGGERNRLLLARLFLKPSNLLILD 465


                 ....*..
gi 657054004 167 EPLGALD 173
Cdd:PRK11147 466 EPTNDLD 472
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 27-223 1.52e-09

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 59.36  E-value: 1.52e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  27 VKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPH-------------KRDIGMvfqnYA 93
Cdd:PRK10982 264 IRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANeainhgfalvteeRRSTGI----YA 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  94 LFP--HMTVAENLAFPLTVRGLSKTdvservKRVLSMVQ--LDAFAQRYPAQ------LSGGQQQRVALARALVFEPQLV 163
Cdd:PRK10982 340 YLDigFNSLISNIRNYKNKVGLLDN------SRMKSDTQwvIDSMRVKTPGHrtqigsLSGGNQQKVIIGRWLLTQPEIL 413

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 164 LMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQI 223
Cdd:PRK10982 414 MLDEPTRGIDVGAKFEIYQLIAELAKK-DKGIIIISSEMPELLGITDRILVMSNGLVAGI 472
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 36-217 3.40e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.07  E-value: 3.40e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    36 KGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGrsinnvpphkrdigmvfqnyalfphmtvaenlafpltvrglsk 115
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYID------------------------------------------- 37

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   116 tdvSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEI-----KHLHQR 190
Cdd:smart00382  38 ---GEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEelrllLLLKSE 114

                          170       180
                   ....*....|....*....|....*..
gi 657054004   191 LGVTVVYVTHDQGEALTMSDRVAVFHQ 217
Cdd:smart00382 115 KNLTVILTTNDEKDLGPALLRRRFDRR 141
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
34-201 4.48e-09

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 57.90  E-value: 4.48e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  34 IRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEIllagrsinNVPPHKRDI-----GMVFQNY-----------ALFPH 97
Cdd:PRK13409  96 PKEGKVTGILGPNGIGKTTAVKILSGELIPNLGDY--------EEEPSWDEVlkrfrGTELQNYfkklyngeikvVHKPQ 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  98 MTVAENLAFPLTVRG-LSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDkqL 176
Cdd:PRK13409 168 YVDLIPKVFKGKVRElLKKVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLD--I 245

                        170       180
                 ....*....|....*....|....*..
gi 657054004 177 REHMQME--IKHLHQrlGVTVVYVTHD 201
Cdd:PRK13409 246 RQRLNVArlIRELAE--GKYVLVVEHD 270
PLN03140 PLN03140
ABC transporter G family member; Provisional
 26-173 5.37e-09

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 57.93  E-value: 5.37e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETP--TAGEILLAGRsinnvpPHKRDI-----GMVFQNYALFPHM 98
Cdd:PLN03140  895 LLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAGRKTGgyIEGDIRISGF------PKKQETfarisGYCEQNDIHSPQV 968

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   99 TVAENLAFPLTVR---GLSKTDVSERVKRVLSMVQLDAFAQR---YPA--QLSGGQQQRVALARALVFEPQLVLMDEPLG 170
Cdd:PLN03140  969 TVRESLIYSAFLRlpkEVSKEEKMMFVDEVMELVELDNLKDAivgLPGvtGLSTEQRKRLTIAVELVANPSIIFMDEPTS 1048


                  ...
gi 657054004  171 ALD 173
Cdd:PLN03140 1049 GLD 1051
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
29-237 5.51e-09

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 56.36  E-value: 5.51e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  29 DLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGrsinnvpphkrDIGMVFQNYALFPHMTVAENLAFPL 108
Cdd:PRK13546  42 DISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNG-----------EVSVIAISAGLSGQLTGIENIEFKM 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 109 TVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQLREHMQMEIKHLH 188
Cdd:PRK13546 111 LCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFK 190

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 657054004 189 QRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTL---YEEPKNTF 237
Cdd:PRK13546 191 EQ-NKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVlpkYEAFLNDF 241
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 121-212 2.00e-08

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 56.11  E-value: 2.00e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 121 RVKRVLSMVQLDAFAQRypAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQlrehmqmEIKHLHQRL---GVTVVY 197
Cdd:PRK11147 138 RINEVLAQLGLDPDAAL--SSLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDIE-------TIEWLEGFLktfQGSIIF 208

                         90
                 ....*....|....*
gi 657054004 198 VTHDQGEALTMSDRV 212
Cdd:PRK11147 209 ISHDRSFIRNMATRI 223
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
21-242 4.03e-08

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 54.42  E-value: 4.03e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  21 DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETP----TAGEILLAGRSINNVPPHKR------DIGMVFQ 90
Cdd:PRK15093  17 DGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDnwrvTADRMRFDDIDLLRLSPRERrklvghNVSMIFQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  91 --NYALFPHMTVAENL--AFP-LTVRGLSKTDVSERVKRVLSMVQL------DAFAQRYPAQLSGGQQQRVALARALVFE 159
Cdd:PRK15093  97 epQSCLDPSERVGRQLmqNIPgWTYKGRWWQRFGWRKRRAIELLHRvgikdhKDAMRSFPYELTEGECQKVMIAIALANQ 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 160 PQLVLMDEPLGALDKQLREHMQMEIKHLHQRLGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTFVA 239
Cdd:PRK15093 177 PRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTTPHHPYTQ 256


                 ...
gi 657054004 240 NFI 242
Cdd:PRK15093 257 ALI 259
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 18-222 6.47e-08

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 53.32  E-value: 6.47e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  18 KSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETpTAGEILLAGRSINNVPPHK--RDIGMVFQNYALF 95
Cdd:cd03289   11 KYTEGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDGVSWNSVPLQKwrKAFGVIPQKVFIF 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  96 PHmTVAENLafplTVRGLSKtdvSERVKRVLSMVQLDAFAQRYPAQL-----------SGGQQQRVALARALVFEPQLVL 164
Cdd:cd03289   90 SG-TFRKNL----DPYGKWS---DEEIWKVAEEVGLKSVIEQFPGQLdfvlvdggcvlSHGHKQLMCLARSVLSKAKILL 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 657054004 165 MDEPLGALDKQLREHMQMEIKHLHQrlGVTVVYVTHdQGEALTMSDRVAVFHQGEIQQ 222
Cdd:cd03289  162 LDEPSAHLDPITYQVIRKTLKQAFA--DCTVILSEH-RIEAMLECQRFLVIEENKVRQ 216
PTZ00243 PTZ00243
ABC transporter; Provisional
 13-237 1.92e-07

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 53.24  E-value: 1.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   13 FRGVQKSY-DGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINN--VPPHKRDIGMVF 89
Cdd:PTZ00243 1311 FEGVQMRYrEGLPLVLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAygLRELRRQFSMIP 1390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   90 QNYALFPHmTVAENL-----AFPLTV-RGLSKTDVSERVKRvlSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQ-L 162
Cdd:PTZ00243 1391 QDPVLFDG-TVRQNVdpfleASSAEVwAALELVGLRERVAS--ESEGIDSRVLEGGSNYSVGQRQLMCMARALLKKGSgF 1467

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004  163 VLMDEPLGALDKQLREHMQMEIKHLHQrlGVTVVYVTHdQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTF 237
Cdd:PTZ00243 1468 ILMDEATANIDPALDRQIQATVMSAFS--AYTVITIAH-RLHTVAQYDKIIVMDHGAVAEMGSPRELVMNRQSIF 1539
GguA NF040905
sugar ABC transporter ATP-binding protein;
23-220 2.04e-07

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 52.48  E-value: 2.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  23 ENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAG--FETPTAGEILLAGRSI--NNVPphkRDI--GMVF-----QN 91
Cdd:NF040905 272 ERKVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGrsYGRNISGTVFKDGKEVdvSTVS---DAIdaGLAYvtedrKG 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  92 YALFPHMTVAENLAFPlTVRGLSK---------TDVSERVKRVLSMVQLDAFAQryPAQLSGGQQQRVALARALVFEPQL 162
Cdd:NF040905 349 YGLNLIDDIKRNITLA-NLGKVSRrgvideneeIKVAEEYRKKMNIKTPSVFQK--VGNLSGGNQQKVVLSKWLFTDPDV 425

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 163 VLMDEP-----LGAldkqlrehmQMEIKHLHQRL---GVTVVYVTHDQGEALTMSDRVAVFHQGEI 220
Cdd:NF040905 426 LILDEPtrgidVGA---------KYEIYTIINELaaeGKGVIVISSELPELLGMCDRIYVMNEGRI 482
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 18-186 4.51e-07

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 51.83  E-value: 4.51e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    18 KSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETpTAGEILLAGRSINNVPPHK--RDIGMVFQNYALF 95
Cdd:TIGR01271 1226 KYTEAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGVSWNSVTLQTwrKAFGVIPQKVFIF 1304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004    96 PHmTVAENLafpltvrglsktDVSER-----VKRVLSMVQLDAFAQRYPAQL-----------SGGQQQRVALARALVFE 159
Cdd:TIGR01271 1305 SG-TFRKNL------------DPYEQwsdeeIWKVAEEVGLKSVIEQFPDKLdfvlvdggyvlSNGHKQLMCLARSILSK 1371

                          170       180
                   ....*....|....*....|....*..
gi 657054004   160 PQLVLMDEPLGALDKQLREHMQMEIKH 186
Cdd:TIGR01271 1372 AKILLLDEPSAHLDPVTLQIIRKTLKQ 1398
PLN03140 PLN03140
ABC transporter G family member; Provisional
 26-241 4.79e-07

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 51.77  E-value: 4.79e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPT---AGEILLAGRSINNVPPHKRDiGMVFQNYALFPHMTVAE 102
Cdd:PLN03140  180 ILKDASGIIKPSRMTLLLGPPSSGKTTLLLALAGKLDPSlkvSGEITYNGYRLNEFVPRKTS-AYISQNDVHVGVMTVKE 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  103 NLAFPLTVRGL-SKTD-VSERVKR-----VLSMVQLDAFAQRYPAQ--------------------------------LS 143
Cdd:PLN03140  259 TLDFSARCQGVgTRYDlLSELARRekdagIFPEAEVDLFMKATAMEgvksslitdytlkilgldickdtivgdemirgIS 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  144 GGQQQRVALARALVFEPQLVLMDEPLGALDK----QLREHMQmEIKHLHQrlGVTVVYVTHDQGEALTMSDRVAVFHQGE 219
Cdd:PLN03140  339 GGQKKRVTTGEMIVGPTKTLFMDEISTGLDSsttyQIVKCLQ-QIVHLTE--ATVLMSLLQPAPETFDLFDDIILLSEGQ 415

                         250       260
                  ....*....|....*....|..
gi 657054004  220 IqqiapprtLYEEPKNTFVANF 241
Cdd:PLN03140  416 I--------VYQGPRDHILEFF 429
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 10-173 9.34e-07

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 50.40  E-value: 9.34e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGfETPT--AGEILLAGR---SINNVPPHKRD 84
Cdd:PRK10938 260 RIVLNNGVVSY-NDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG-DHPQgySNDLTLFGRrrgSGETIWDIKKH 337

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 IGMVFQNYalfpHMTVAENLafplTVR-----------GLSKTdVSERVKRV----LSMVQLDAFAQRYPAQ-LSGGQQQ 148
Cdd:PRK10938 338 IGYVSSSL----HLDYRVST----SVRnvilsgffdsiGIYQA-VSDRQQKLaqqwLDILGIDKRTADAPFHsLSWGQQR 408

                        170       180
                 ....*....|....*....|....*
gi 657054004 149 RVALARALVFEPQLVLMDEPLGALD 173
Cdd:PRK10938 409 LALIVRALVKHPTLLILDEPLQGLD 433
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 10-221 1.23e-06

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 50.17  E-value: 1.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYdGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLA-GRSINNVPPHK----RD 84
Cdd:PRK10636 312 LLKMEKVSAGY-GDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAkGIKLGYFAQHQleflRA 390

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 IGMVFQNYALFPHMTVAENLAFPLTVRGLSKTDVSERVKRvlsmvqldafaqrypaqLSGGQQQRVALARALVFEPQLVL 164
Cdd:PRK10636 391 DESPLQHLARLAPQELEQKLRDYLGGFGFQGDKVTEETRR-----------------FSGGEKARLVLALIVWQRPNLLL 453

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 657054004 165 MDEPLGALDKQLRehmQMEIKHLHQRLGVTVVyVTHDQGEALTMSDRVAVFHQGEIQ 221
Cdd:PRK10636 454 LDEPTNHLDLDMR---QALTEALIDFEGALVV-VSHDRHLLRSTTDDLYLVHDGKVE 506
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 31-223 1.61e-06

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 49.63  E-value: 1.61e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  31 NLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSI------------------NN---VPPHKRDIGMvf 89
Cdd:PRK10938  23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQFSHItrlsfeqlqklvsdewqrNNtdmLSPGEDDTGR-- 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 qnyalfphmTVAENLafpltvrgLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPL 169
Cdd:PRK10938 101 ---------TTAEII--------QDEVKDPARCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPF 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 170 GALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVF------HQGEIQQI 223
Cdd:PRK10938 164 DGLDVASRQQLAELLASLHQS-GITLVLVLNRFDEIPDFVQFAGVLadctlaETGEREEI 222
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 18-222 2.60e-06

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 49.12  E-value: 2.60e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  18 KSYDGE-NLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSinnvpphkrdiGMVFQNYALFP 96
Cdd:PRK13545  30 RSKDGEyHYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSA-----------ALIAISSGLNG 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  97 HMTVAENLAFPLTVRGLSKTDVSERVKRVLSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQL 176
Cdd:PRK13545  99 QLTGIENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTF 178

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 657054004 177 REHMQMEIKHLHQRlGVTVVYVTHDQGEALTMSDRVAVFHQGEIQQ 222
Cdd:PRK13545 179 TKKCLDKMNEFKEQ-GKTIFFISHSLSQVKSFCTKALWLHYGQVKE 223
PLN03073 PLN03073
ABC transporter F family; Provisional
 10-173 5.24e-06

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 48.32  E-value: 5.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  10 LVSFRGVQKSYDGENLIVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILlagRSinnvpPHKRdiGMVF 89
Cdd:PLN03073 508 IISFSDASFGYPGGPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVF---RS-----AKVR--MAVF 577

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  90 QNYalfpHMTVAENLAFPLTVRGLSKTDVSERVKRVlsmvQLDAF------AQRYPAQLSGGQQQRVALARALVFEPQLV 163
Cdd:PLN03073 578 SQH----HVDGLDLSSNPLLYMMRCFPGVPEQKLRA----HLGSFgvtgnlALQPMYTLSGGQKSRVAFAKITFKKPHIL 649

                        170
                 ....*....|
gi 657054004 164 LMDEPLGALD 173
Cdd:PLN03073 650 LLDEPSNHLD 659
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 26-237 6.12e-06

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 47.21  E-value: 6.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  26 IVKDLNLDIRKGEFLTLLGPSGSGKTT-SLM---MLAGFEtptaGEILLAGRSINNVPPH--KRDIGMVFQNYALFPHmT 99
Cdd:cd03288   36 VLKHVKAYIKPGQKVGICGRTGSGKSSlSLAffrMVDIFD----GKIVIDGIDISKLPLHtlRSRLSIILQDPILFSG-S 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004 100 VAENLAfPltvrglSKTDVSERVKRVLSMVQLDAFAQRYPAQL-----------SGGQQQRVALARALVFEPQLVLMDEP 168
Cdd:cd03288  111 IRFNLD-P------ECKCTDDRLWEALEIAQLKNMVKSLPGGLdavvteggenfSVGQRQLFCLARAFVRKSSILIMDEA 183

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657054004 169 LGALDkqlrehmqMEIKHLHQRLGV------TVVYVTHDQGEALTmSDRVAVFHQGEIQQIAPPRTLYEEPKNTF 237
Cdd:cd03288  184 TASID--------MATENILQKVVMtafadrTVVTIAHRVSTILD-ADLVLVLSRGILVECDTPENLLAQEDGVF 249
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 142-201 3.68e-05

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 43.85  E-value: 3.68e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 657054004 142 LSGGQQQRVALARALVFEPQ--LVLMDEPLGALDKQLREHMQMEIKHLHQrLGVTVVYVTHD 201
Cdd:cd03238   88 LSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQDINQLLEVIKGLID-LGNTVILIEHN 148
PLN03073 PLN03073
ABC transporter F family; Provisional
 141-173 5.51e-05

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 45.24  E-value: 5.51e-05
                         10        20        30
                 ....*....|....*....|....*....|...
gi 657054004 141 QLSGGQQQRVALARALVFEPQLVLMDEPLGALD 173
Cdd:PLN03073 344 TFSGGWRMRIALARALFIEPDLLLLDEPTNHLD 376
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
 24-220 3.95e-04

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 41.47  E-value: 3.95e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  24 NLivKDLNLDIRKGEFLTLLGPSGSGKTTslmmLAgFETptageILLAG--RSINNVPPHKRD----------------- 84
Cdd:cd03270   10 NL--KNVDVDIPRNKLVVITGVSGSGKSS----LA-FDT-----IYAEGqrRYVESLSAYARQflgqmdkpdvdsiegls 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  85 --IGMVFQNYALFPHMTVAenlafplTVRGL--------SKTDVSERVkRVLSMVQLDAFA-QRYPAQLSGGQQQRVALA 153
Cdd:cd03270   78 paIAIDQKTTSRNPRSTVG-------TVTEIydylrllfARVGIRERL-GFLVDVGLGYLTlSRSAPTLSGGEAQRIRLA 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 657054004 154 RALvfEPQLV----LMDEPLGALDKQLREHMQMEIKHLhQRLGVTVVYVTHDQgEALTMSDRV------AVFHQGEI 220
Cdd:cd03270  150 TQI--GSGLTgvlyVLDEPSIGLHPRDNDRLIETLKRL-RDLGNTVLVVEHDE-DTIRAADHVidigpgAGVHGGEI 222
PLN03232 PLN03232
ABC transporter C family member; Provisional
 26-237 8.49e-04

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 41.50  E-value: 8.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004   26 IVKDLNLDIRKGEFLTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINN--VPPHKRDIGMVFQNYALFPHmTVAEN 103
Cdd:PLN03232 1251 VLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKfgLTDLRRVLSIIPQSPVLFSG-TVRFN 1329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  104 LAfPLTV-------RGLSKTDVSERVKRvlSMVQLDAFAQRYPAQLSGGQQQRVALARALVFEPQLVLMDEPLGALDKQL 176
Cdd:PLN03232 1330 ID-PFSEhndadlwEALERAHIKDVIDR--NPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDVRT 1406

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657054004  177 REHMQMEIKHLHQrlGVTVVYVTHdQGEALTMSDRVAVFHQGEIQQIAPPRTLYEEPKNTF 237
Cdd:PLN03232 1407 DSLIQRTIREEFK--SCTMLVIAH-RLNTIIDCDKILVLSSGQVLEYDSPQELLSRDTSAF 1464
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 136-212 1.26e-03

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 40.97  E-value: 1.26e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 657054004  136 QRYPAQLSGGQQQRVALARALVFEPQLV--LMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQgEALTMSDRV 212
Cdd:PRK00635  471 ERALATLSGGEQERTALAKHLGAELIGItyILDEPSIGLHPQDTHKLINVIKKLRDQ-GNTVLLVEHDE-QMISLADRI 547
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 137-234 2.17e-03

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 40.00  E-value: 2.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657054004  137 RYPAQLSGGQQQRVALARALVFEPQLVL--MDEPLGALDKQLREHMQMEIKHLhQRLGVTVVYVTHDQgEALTMSDRV-- 212
Cdd:TIGR00630 484 RAAGTLSGGEAQRIRLATQIGSGLTGVLyvLDEPSIGLHQRDNRRLINTLKRL-RDLGNTLIVVEHDE-DTIRAADYVid 561

                          90       100
                  ....*....|....*....|....*.
gi 657054004  213 ----AVFHQGEIQQIAPPRTLYEEPK 234
Cdd:TIGR00630 562 igpgAGEHGGEVVASGTPEEILANPD 587
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 141-202 5.08e-03

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 37.34  E-value: 5.08e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657054004 141 QLSGGQQQRVALARAL----VFEPQLVLMDEPLGALDKQLREHMQMEIKHLHQRlGVTVVYVTHDQ 202
Cdd:cd03227   77 QLSGGEKELSALALILalasLKPRPLYILDEIDRGLDPRDGQALAEAILEHLVK-GAQVIVITHLP 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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