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Conserved domains on  [gi|657349308|ref|WP_029405988|]
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MULTISPECIES: phosphopyruvate hydratase [Vibrio]

Protein Classification

phosphopyruvate hydratase( domain architecture ID 11414960)

phosphopyruvate hydratase (enolase) catalyzes the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways

CATH:  3.20.20.120|3.30.390.10
EC:  4.2.1.11
Gene Ontology:  GO:0004634|GO:0000015|GO:0006096|GO:0000287
PubMed:  8994873|8605183
SCOP:  3001064|3000476

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-431 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


:

Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 810.40  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308   1 MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAIEAVNGPIADALV 80
Cdd:COG0148    1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  81 GKDAKAQADVDQVMIDLDGTENKSQFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGtagqFSMPLPMMNIINGGEHA 160
Cdd:COG0148   81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNA----KTLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 161 DNNVDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKGYSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKD 240
Cdd:COG0148  157 DNNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 241 VTLAMDCAASEFFDKeaGIYNMKGEGKTFTSEEFNHYLAELANNFPIVSIEDGLDESDWDGFKHQTELLGDKLQIVGDDL 320
Cdd:COG0148  237 IALALDVAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDL 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 321 FVTNTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSR 400
Cdd:COG0148  315 FVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSR 394

                        410       420       430
                 ....*....|....*....|....*....|.
gi 657349308 401 SDRVAKYNQLIRIEEALGSKAPFNGLKEVKG 431
Cdd:COG0148  395 SERVAKYNQLLRIEEELGDAARYAGRSAFKR 425
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-431 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 810.40  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308   1 MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAIEAVNGPIADALV 80
Cdd:COG0148    1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  81 GKDAKAQADVDQVMIDLDGTENKSQFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGtagqFSMPLPMMNIINGGEHA 160
Cdd:COG0148   81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNA----KTLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 161 DNNVDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKGYSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKD 240
Cdd:COG0148  157 DNNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 241 VTLAMDCAASEFFDKeaGIYNMKGEGKTFTSEEFNHYLAELANNFPIVSIEDGLDESDWDGFKHQTELLGDKLQIVGDDL 320
Cdd:COG0148  237 IALALDVAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDL 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 321 FVTNTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSR 400
Cdd:COG0148  315 FVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSR 394

                        410       420       430
                 ....*....|....*....|....*....|.
gi 657349308 401 SDRVAKYNQLIRIEEALGSKAPFNGLKEVKG 431
Cdd:COG0148  395 SERVAKYNQLLRIEEELGDAARYAGRSAFKR 425
eno PRK00077
enolase; Provisional
 1-432 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 784.28  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308   1 MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAIEAVNGPIADALV 80
Cdd:PRK00077   1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  81 GKDAKAQADVDQVMIDLDGTENKSQFGANAILAVSLANAKAAAAAKGMPLYEHIaelnGTAGQFSMPLPMMNIINGGEHA 160
Cdd:PRK00077  81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYL----GGPNAKVLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 161 DNNVDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKGYSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKD 240
Cdd:PRK00077 157 DNNVDIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 241 VTLAMDCAASEFFDKeaGIYNMKGEGktFTSEEFNHYLAELANNFPIVSIEDGLDESDWDGFKHQTELLGDKLQIVGDDL 320
Cdd:PRK00077 237 IALALDCAASEFYKD--GKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDL 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 321 FVTNTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSR 400
Cdd:PRK00077 313 FVTNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSR 392

                        410       420       430
                 ....*....|....*....|....*....|..
gi 657349308 401 SDRVAKYNQLIRIEEALGSKAPFNGLKEVKGQ 432
Cdd:PRK00077 393 SERIAKYNQLLRIEEELGDAARYAGKKAFKNL 424
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 4-432 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 696.42  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308    4 IVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAIEAVNGPIADALVGKD 83
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308   84 AKAQADVDQVMIDLDGTENKSQFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGtagqFSMPLPMMNIINGGEHADNN 163
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNA----YVLPVPMMNIINGGAHADNN 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  164 VDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKGYSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKDVTL 243
Cdd:TIGR01060 157 LDFQEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVAL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  244 AMDCAASEFFDKEAGIYNMKGEGKTFTSEEFNHYLAELANNFPIVSIEDGLDESDWDGFKHQTELLGDKLQIVGDDLFVT 323
Cdd:TIGR01060 237 ALDCAASEFYDEEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVT 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  324 NTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDR 403
Cdd:TIGR01060 317 NTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSER 396

                         410       420
                  ....*....|....*....|....*....
gi 657349308  404 VAKYNQLIRIEEALGSKAPFNGLKEVKGQ 432
Cdd:TIGR01060 397 IAKYNQLLRIEEELGDSARYAGKNSFYRF 425
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 6-415 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 670.34  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308   6 KVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAIEAVNGPIADALVGKDAK 85
Cdd:cd03313    1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  86 AQADVDQVMIDLDGTENKSQFGANAILAVSLANAKAAAAAKGMPLYEHIAELNgtagQFSMPLPMMNIINGGEHADNNVD 165
Cdd:cd03313   81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLA----AYVLPVPMFNVINGGAHAGNKLD 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 166 IQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKG--YSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKDVTL 243
Cdd:cd03313  157 FQEFMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAI 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 244 AMDCAASEFFDKEAGIYNmKGEGKTFTSEEFNHYLAELANNFPIVSIEDGLDESDWDGFKHQTELLGDKLQIVGDDLFVT 323
Cdd:cd03313  237 ALDVAASEFYDEGKYVYD-SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVT 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 324 NTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDR 403
Cdd:cd03313  316 NPERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSER 395

                        410
                 ....*....|..
gi 657349308 404 VAKYNQLIRIEE 415
Cdd:cd03313  396 TAKYNQLLRIEE 407
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
144-432 4.72e-155

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 440.38  E-value: 4.72e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  144 FSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKGYS--TAVGDEGGFAPNLKSNAE 221
Cdd:pfam00113   2 YVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGQsaTNVGDEGGFAPNLQSNKE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  222 ALEVIAEAVAAAGYELgkDVTLAMDCAASEFFDKEAGIYNMKGEG------KTFTSEEFNHYLAELANNFPIVSIEDGLD 295
Cdd:pfam00113  82 ALDLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPFD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  296 ESDWDGFKHQTELLGDKLQIVGDDLFVTNTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGE 375
Cdd:pfam00113 160 EDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGE 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 657349308  376 TEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGSKAPFNGLKEVKGQ 432
Cdd:pfam00113 240 TEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-431 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 810.40  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308   1 MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAIEAVNGPIADALV 80
Cdd:COG0148    1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  81 GKDAKAQADVDQVMIDLDGTENKSQFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGtagqFSMPLPMMNIINGGEHA 160
Cdd:COG0148   81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNA----KTLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 161 DNNVDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKGYSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKD 240
Cdd:COG0148  157 DNNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 241 VTLAMDCAASEFFDKeaGIYNMKGEGKTFTSEEFNHYLAELANNFPIVSIEDGLDESDWDGFKHQTELLGDKLQIVGDDL 320
Cdd:COG0148  237 IALALDVAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDL 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 321 FVTNTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSR 400
Cdd:COG0148  315 FVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSR 394

                        410       420       430
                 ....*....|....*....|....*....|.
gi 657349308 401 SDRVAKYNQLIRIEEALGSKAPFNGLKEVKG 431
Cdd:COG0148  395 SERVAKYNQLLRIEEELGDAARYAGRSAFKR 425
eno PRK00077
enolase; Provisional
 1-432 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 784.28  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308   1 MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAIEAVNGPIADALV 80
Cdd:PRK00077   1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  81 GKDAKAQADVDQVMIDLDGTENKSQFGANAILAVSLANAKAAAAAKGMPLYEHIaelnGTAGQFSMPLPMMNIINGGEHA 160
Cdd:PRK00077  81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYL----GGPNAKVLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 161 DNNVDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKGYSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKD 240
Cdd:PRK00077 157 DNNVDIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 241 VTLAMDCAASEFFDKeaGIYNMKGEGktFTSEEFNHYLAELANNFPIVSIEDGLDESDWDGFKHQTELLGDKLQIVGDDL 320
Cdd:PRK00077 237 IALALDCAASEFYKD--GKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDL 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 321 FVTNTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSR 400
Cdd:PRK00077 313 FVTNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSR 392

                        410       420       430
                 ....*....|....*....|....*....|..
gi 657349308 401 SDRVAKYNQLIRIEEALGSKAPFNGLKEVKGQ 432
Cdd:PRK00077 393 SERIAKYNQLLRIEEELGDAARYAGKKAFKNL 424
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 4-432 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 696.42  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308    4 IVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAIEAVNGPIADALVGKD 83
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308   84 AKAQADVDQVMIDLDGTENKSQFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGtagqFSMPLPMMNIINGGEHADNN 163
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNA----YVLPVPMMNIINGGAHADNN 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  164 VDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKGYSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKDVTL 243
Cdd:TIGR01060 157 LDFQEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVAL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  244 AMDCAASEFFDKEAGIYNMKGEGKTFTSEEFNHYLAELANNFPIVSIEDGLDESDWDGFKHQTELLGDKLQIVGDDLFVT 323
Cdd:TIGR01060 237 ALDCAASEFYDEEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVT 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  324 NTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDR 403
Cdd:TIGR01060 317 NTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSER 396

                         410       420
                  ....*....|....*....|....*....
gi 657349308  404 VAKYNQLIRIEEALGSKAPFNGLKEVKGQ 432
Cdd:TIGR01060 397 IAKYNQLLRIEEELGDSARYAGKNSFYRF 425
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 6-415 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 670.34  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308   6 KVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAIEAVNGPIADALVGKDAK 85
Cdd:cd03313    1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  86 AQADVDQVMIDLDGTENKSQFGANAILAVSLANAKAAAAAKGMPLYEHIAELNgtagQFSMPLPMMNIINGGEHADNNVD 165
Cdd:cd03313   81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLA----AYVLPVPMFNVINGGAHAGNKLD 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 166 IQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKG--YSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKDVTL 243
Cdd:cd03313  157 FQEFMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAI 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 244 AMDCAASEFFDKEAGIYNmKGEGKTFTSEEFNHYLAELANNFPIVSIEDGLDESDWDGFKHQTELLGDKLQIVGDDLFVT 323
Cdd:cd03313  237 ALDVAASEFYDEGKYVYD-SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVT 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 324 NTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDR 403
Cdd:cd03313  316 NPERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSER 395

                        410
                 ....*....|..
gi 657349308 404 VAKYNQLIRIEE 415
Cdd:cd03313  396 TAKYNQLLRIEE 407
PTZ00081 PTZ00081
enolase; Provisional
 1-425 0e+00

enolase; Provisional


Pssm-ID: 240259 [Multi-domain]  Cd Length: 439  Bit Score: 531.93  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308   1 MSKIVKVLGREIIDSRGNPTVEAEVHLEGGfVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAIEAVNGPIADALV 80
Cdd:PTZ00081   1 MSTIKSIKAREILDSRGNPTVEVDLTTEKG-VFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  81 GKDAKAQADVDQVMID-LDGTEN-----KSQFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTAG-QFSMPLPMMNI 153
Cdd:PTZ00081  80 GKDVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQLAGKPTdKFVLPVPCFNV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 154 INGGEHADNNVDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKgY---STAVGDEGGFAPNLKSNAEALEVIAEAV 230
Cdd:PTZ00081 160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKK-YgldATNVGDEGGFAPNIKDPEEALDLLVEAI 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 231 AAAGYElGKdVTLAMDCAASEFFDKEAGIYNM-----KGEGKTF-TSEEFNHYLAELANNFPIVSIEDGLDESDWDGFKH 304
Cdd:PTZ00081 239 KKAGYE-GK-VKICMDVAASEFYDKEKKVYDLdfknpNNDKSNKlTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAK 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 305 QTELLGDKLQIVGDDLFVTNTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADL 384
Cdd:PTZ00081 317 LTAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADL 396

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|.
gi 657349308 385 AVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGSKAPFNG 425
Cdd:PTZ00081 397 VVGLGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAG 437
PLN00191 PLN00191
enolase
 1-425 1.37e-178

enolase


Pssm-ID: 215095 [Multi-domain]  Cd Length: 457  Bit Score: 506.17  E-value: 1.37e-178
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308   1 MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFVgMAAAPSGASTGSREALELRDGDKsRFLGKGVLKAIEAVNGPIADALV 80
Cdd:PLN00191  25 MATITKVKARQIIDSRGNPTVEVDLHTSKGMF-RAAVPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPALI 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  81 GKDAKAQADVDQVMIDLDGTENKSQFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTAgQFSMPLPMMNIINGGEHA 160
Cdd:PLN00191 103 GMDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHIADLAGNK-KLVLPVPAFNVINGGSHA 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 161 DNNVDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSK--GYSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYElG 238
Cdd:PLN00191 182 GNKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYT-G 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 239 KdVTLAMDCAASEFFDKEaGIY--NMKGEGKT----FTSEEFNHYLAELANNFPIVSIEDGLDESDWDGFKHQTELlgDK 312
Cdd:PLN00191 261 K-IKIGMDVAASEFYTKD-KKYdlDFKEENNDgsnkKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSL--ED 336

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 313 LQIVGDDLFVTNTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQ 392
Cdd:PLN00191 337 VQIVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQ 416

                        410       420       430
                 ....*....|....*....|....*....|...
gi 657349308 393 IKTGSMSRSDRVAKYNQLIRIEEALGSKAPFNG 425
Cdd:PLN00191 417 IKTGAPCRSERLAKYNQLLRIEEELGDEAVYAG 449
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
144-432 4.72e-155

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 440.38  E-value: 4.72e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  144 FSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKGYS--TAVGDEGGFAPNLKSNAE 221
Cdd:pfam00113   2 YVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGQsaTNVGDEGGFAPNLQSNKE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  222 ALEVIAEAVAAAGYELgkDVTLAMDCAASEFFDKEAGIYNMKGEG------KTFTSEEFNHYLAELANNFPIVSIEDGLD 295
Cdd:pfam00113  82 ALDLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPFD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  296 ESDWDGFKHQTELLGDKLQIVGDDLFVTNTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGE 375
Cdd:pfam00113 160 EDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGE 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 657349308  376 TEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGSKAPFNGLKEVKGQ 432
Cdd:pfam00113 240 TEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
Enolase_N pfam03952
Enolase, N-terminal domain;
4-134 1.55e-72

Enolase, N-terminal domain;


Pssm-ID: 461105 [Multi-domain]  Cd Length: 131  Bit Score: 223.79  E-value: 1.55e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308    4 IVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAIEAVNGPIADALVGKD 83
Cdd:pfam03952   1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 657349308   84 AKAQADVDQVMIDLDGTENKSQFGANAILAVSLANAKAAAAAKGMPLYEHI 134
Cdd:pfam03952  81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
PRK08350 PRK08350
hypothetical protein; Provisional
 1-420 3.02e-10

hypothetical protein; Provisional


Pssm-ID: 169397 [Multi-domain]  Cd Length: 341  Bit Score: 61.36  E-value: 3.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308   1 MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFvGMAAAPSgastgsrealelrDGDKSRFLGKGvLKAIEAVNGPIADALV 80
Cdd:PRK08350   1 MTVIENIIGRVAVLRGGKYSVEVDVITDSGF-GRFAAPI-------------DENPSLYIAEA-HRAVSEVDEIIGPELI 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308  81 GKDAKAQADVDQVMIDLDGTENKSQFGANAILAVSLANAKAAAAAKGMPLYEHIaelngtAGQFS--MPLPMMNIINgGE 158
Cdd:PRK08350  66 GFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYI------GGTFTteLPVPILEFAE-DE 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 159 HADNNVDIQEFMiqpvgaktlkeglrigaEVFHNLAKVLKSKGYSTAVGDEGgfapnLKSNAEaleviaeavaAAGYELG 238
Cdd:PRK08350 139 NFEYYVLVRDLM-----------------EITDVVDAVNKILENSKEVSLEG-----LSKASE----------KAGDELG 186

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 239 KDVTLAMdcaaseffdkeagiyNMKGEGKTftsEEfnhyLAELANNFPIVSIEDGLDESDWdgfkhqTELLGDK--LQIV 316
Cdd:PRK08350 187 LEVALGI---------------AQKREMET---EK----VLNLVEDNNIAYIKPIGDEELF------LELIAGThgVFID 238

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 317 GDDLFVTNTKilaegIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIktg 396
Cdd:PRK08350 239 GEYLFRTRNI-----LDRRYYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLRCPAM--- 310

                        410       420
                 ....*....|....*....|....
gi 657349308 397 sMSRSDRVAKYNQLIRIEEALGSK 420
Cdd:PRK08350 311 -LIHKDSVEKINELNRIAEDLGER 333
enolase_like cd00308
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ...
 276-388 2.16e-09

Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.


Pssm-ID: 238188 [Multi-domain]  Cd Length: 229  Bit Score: 57.34  E-value: 2.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 276 HYLAElannFPIVSIEDGLDESDWDGFKHQTELLGdkLQIVGDDLFVTNTKILaEGIEKGVANSILIKFNQIGSLTETLA 355
Cdd:cd00308  115 RALEK----YGLAWIEEPCAPDDLEGYAALRRRTG--IPIAADESVTTVDDAL-EALELGAVDILQIKPTRVGGLTESRR 187

                         90       100       110
                 ....*....|....*....|....*....|....
gi 657349308 356 AIKMAKDAGYTAVISHRSG-ETEDATIADLAVGT 388
Cdd:cd00308  188 AADLAEAFGIRVMVHGTLEsSIGTAAALHLAAAL 221
PTZ00378 PTZ00378
hypothetical protein; Provisional
 128-420 2.88e-04

hypothetical protein; Provisional


Pssm-ID: 173571 [Multi-domain]  Cd Length: 518  Bit Score: 42.94  E-value: 2.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 128 MPLYEHIAELNGTAG---QFSMPLPMMNIINGGEHADNNVDIQEFMIQPV--GAKTLKEGLRIGAEVFHNLAKVlkskgY 202
Cdd:PTZ00378 168 VPLFQYLRALFGSLTsveTFSMPQLCITFFGPGNPSTARLALKSVLFSPVmpSGTVLRERMQKIFAAFHHFCQS-----H 242

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 203 STAVGDEGGFAPNLKSN-AEALEVIAEAVAAAGYELGKDVTLAMDCAASEFFDKEAG------IYNMKGEGKTF------ 269
Cdd:PTZ00378 243 NSSVRSDGSLHWDGFANlTDAVKLATEALRAVQLTPGTDVCLGLRMAASTTRVPATAvadggaWKEAKDDCEVLyslfpg 322

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657349308 270 ----TSEEFNHYLAELANNFP--IVSIEDGLDESDWDGFKHQTELLGDKLQIVGDDLFV-TNTKILAEGIEKGVANSILI 342
Cdd:PTZ00378 323 epdvTGDQLSEYVREQLQAVPdiVVYVEDTHCDEDTFGLQRLQAALGDSIVLSGVDVYArSEYKKVESGLRGLWTSNIVL 402

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 657349308 343 KFNQIGSLTETLAAIKMAK-DAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGSK 420
Cdd:PTZ00378 403 NPCAIGTLSDVVEIVRAVGeDEGRAVTVLVQTLAGNAATAAHLAVAMGARFLCSGGLFSAHQCEVVSQLASRQDELTHS 481
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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