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Conserved domains on  [gi|657873431|ref|WP_029577992|]
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MULTISPECIES: muconolactone Delta-isomerase [Bordetella]

Protein Classification

muconolactone Delta-isomerase( domain architecture ID 10022251)

muconolactone Delta-isomerase that catalyzes the reversible conversion of (S)-muconolactone to (4,5-dihydro-5-oxofuran-2-yl)-acetate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
muco_delta TIGR03221
muconolactone delta-isomerase; Members of this protein family are muconolactone ...
 2-91 1.13e-56

muconolactone delta-isomerase; Members of this protein family are muconolactone delta-isomerase (EC 5.3.3.4), the CatC protein of the ortho cleavage pathway for metabolizing aromatic compounds by way of catechol. [Energy metabolism, Other]


:

Pssm-ID: 213786  Cd Length: 90  Bit Score: 169.16  E-value: 1.13e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657873431   2 LYMVEMQVNLPPDMPADKADKLKADEKALAQKLQHEGKWQSLWRVVGRYANVSIFNVDSHDELHQLLSSLPLFPYMDIRV 81
Cdd:TIGR03221  1 LFHVRMDVNLPVDMPAEKAAAIKAREKAYAQELQREGKWRHLWRVAGEYANYSIFDVESNDELHTLLSGLPLFPYMDIEV 80

                         90
                 ....*....|
gi 657873431  82 TALARHPSAI 91
Cdd:TIGR03221 81 TPLARHPSSI 90
 
Name Accession Description Interval E-value
muco_delta TIGR03221
muconolactone delta-isomerase; Members of this protein family are muconolactone ...
 2-91 1.13e-56

muconolactone delta-isomerase; Members of this protein family are muconolactone delta-isomerase (EC 5.3.3.4), the CatC protein of the ortho cleavage pathway for metabolizing aromatic compounds by way of catechol. [Energy metabolism, Other]


Pssm-ID: 213786  Cd Length: 90  Bit Score: 169.16  E-value: 1.13e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657873431   2 LYMVEMQVNLPPDMPADKADKLKADEKALAQKLQHEGKWQSLWRVVGRYANVSIFNVDSHDELHQLLSSLPLFPYMDIRV 81
Cdd:TIGR03221  1 LFHVRMDVNLPVDMPAEKAAAIKAREKAYAQELQREGKWRHLWRVAGEYANYSIFDVESNDELHTLLSGLPLFPYMDIEV 80

                         90
                 ....*....|
gi 657873431  82 TALARHPSAI 91
Cdd:TIGR03221 81 TPLARHPSSI 90
MIase pfam02426
Muconolactone delta-isomerase; This small enzyme forms a homodecameric complex, that catalyzes ...
 2-90 9.98e-51

Muconolactone delta-isomerase; This small enzyme forms a homodecameric complex, that catalyzes the third step in the catabolism of catechol to succinate- and acetyl-coa in the beta-ketoadipate pathway EC:5.3.3.4. The protein has a ferredoxin-like fold according to SCOP.


Pssm-ID: 426768  Cd Length: 89  Bit Score: 154.26  E-value: 9.98e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657873431   2 LYMVEMQVNLPPDMPADKADKLKADEKALAQKLQHEGKWQSLWRVVGRYANVSIFNVDSHDELHQLLSSLPLFPYMDIRV 81
Cdd:pfam02426  1 LFLVRMTVNVPPDMPAEEVDDLKAREKARAQELQRQGKWVHLWRVAGEYANISIFDVEDNDELHELLSSLPLFPYMTIEV 80


                 ....*....
gi 657873431  82 TALARHPSA 90
Cdd:pfam02426 81 TPLARHPSD 89
CatC1 COG4829
Muconolactone delta-isomerase [Secondary metabolites biosynthesis, transport and catabolism];
1-91 1.30e-50

Muconolactone delta-isomerase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443857  Cd Length: 96  Bit Score: 153.89  E-value: 1.30e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657873431  1 MLYMVEMQVNLPPDMPADKADKLKADEKALAQKLQHEGKWQSLWRVVGRYANVSIFNVDSHDELHQLLSSLPLFPYMDIR 80
Cdd:COG4829   1 MLFLVRMTVRIPPDMPAEEVDELKAREKAYAQELQRQGKWVHLWRVVGRYANISIFDVESNEELHAILSSLPLFPYMEIE 80

                        90
                ....*....|.
gi 657873431 81 VTALARHPSAI 91
Cdd:COG4829  81 VTPLAPHPSDI 91
 
Name Accession Description Interval E-value
muco_delta TIGR03221
muconolactone delta-isomerase; Members of this protein family are muconolactone ...
 2-91 1.13e-56

muconolactone delta-isomerase; Members of this protein family are muconolactone delta-isomerase (EC 5.3.3.4), the CatC protein of the ortho cleavage pathway for metabolizing aromatic compounds by way of catechol. [Energy metabolism, Other]


Pssm-ID: 213786  Cd Length: 90  Bit Score: 169.16  E-value: 1.13e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657873431   2 LYMVEMQVNLPPDMPADKADKLKADEKALAQKLQHEGKWQSLWRVVGRYANVSIFNVDSHDELHQLLSSLPLFPYMDIRV 81
Cdd:TIGR03221  1 LFHVRMDVNLPVDMPAEKAAAIKAREKAYAQELQREGKWRHLWRVAGEYANYSIFDVESNDELHTLLSGLPLFPYMDIEV 80

                         90
                 ....*....|
gi 657873431  82 TALARHPSAI 91
Cdd:TIGR03221 81 TPLARHPSSI 90
MIase pfam02426
Muconolactone delta-isomerase; This small enzyme forms a homodecameric complex, that catalyzes ...
 2-90 9.98e-51

Muconolactone delta-isomerase; This small enzyme forms a homodecameric complex, that catalyzes the third step in the catabolism of catechol to succinate- and acetyl-coa in the beta-ketoadipate pathway EC:5.3.3.4. The protein has a ferredoxin-like fold according to SCOP.


Pssm-ID: 426768  Cd Length: 89  Bit Score: 154.26  E-value: 9.98e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657873431   2 LYMVEMQVNLPPDMPADKADKLKADEKALAQKLQHEGKWQSLWRVVGRYANVSIFNVDSHDELHQLLSSLPLFPYMDIRV 81
Cdd:pfam02426  1 LFLVRMTVNVPPDMPAEEVDDLKAREKARAQELQRQGKWVHLWRVAGEYANISIFDVEDNDELHELLSSLPLFPYMTIEV 80


                 ....*....
gi 657873431  82 TALARHPSA 90
Cdd:pfam02426 81 TPLARHPSD 89
CatC1 COG4829
Muconolactone delta-isomerase [Secondary metabolites biosynthesis, transport and catabolism];
1-91 1.30e-50

Muconolactone delta-isomerase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443857  Cd Length: 96  Bit Score: 153.89  E-value: 1.30e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657873431  1 MLYMVEMQVNLPPDMPADKADKLKADEKALAQKLQHEGKWQSLWRVVGRYANVSIFNVDSHDELHQLLSSLPLFPYMDIR 80
Cdd:COG4829   1 MLFLVRMTVRIPPDMPAEEVDELKAREKAYAQELQRQGKWVHLWRVVGRYANISIFDVESNEELHAILSSLPLFPYMEIE 80

                        90
                ....*....|.
gi 657873431 81 VTALARHPSAI 91
Cdd:COG4829  81 VTPLAPHPSDI 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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