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Conserved domains on  [gi|658751199|ref|WP_029771921|]
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MULTISPECIES: phosphopyruvate hydratase [Pseudoalteromonas]

Protein Classification

phosphopyruvate hydratase( domain architecture ID 11414960)

phosphopyruvate hydratase (enolase) catalyzes the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways

CATH:  3.20.20.120|3.30.390.10
EC:  4.2.1.11
Gene Ontology:  GO:0004634|GO:0000015|GO:0006096|GO:0000287
PubMed:  8994873|8605183
SCOP:  3001064|3000476

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-431 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


:

Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 845.84  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199   1 MSEIVKVIGREIMDSRGNPTVEADVYLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLNAVGFINNEIADALK 80
Cdd:COG0148    1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  81 GQNALEQSAVDKVMLDLDGTENKEKLGANAILAVSLATAKAAAQFKKVELYEHIADLNGtpgvYSMPLPMMNIINGGEHA 160
Cdd:COG0148   81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNA----KTLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 161 DNSVDIQEFMIQPVGAENFREGLRMGAEVFHSLAKVLKADGHSTAVGDEGGFAPNLASNEAALAAIKTAVANAGYELGKD 240
Cdd:COG0148  157 DNNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 241 ITLAMDCAASEFYDKeaNIYDLKGEGKKFTSEEFNYFLKDLTEQYPIVSIEDGLDESDWDGFAHQTKLMGDKIQLVGDDL 320
Cdd:COG0148  237 IALALDVAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDL 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 321 FVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDATIADLAVGTAAGQIKTGSLSR 400
Cdd:COG0148  315 FVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSR 394

                        410       420       430
                 ....*....|....*....|....*....|.
gi 658751199 401 SDRVAKYNQLLRIEEALGSKAPYNGLKEVKG 431
Cdd:COG0148  395 SERVAKYNQLLRIEEELGDAARYAGRSAFKR 425
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-431 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 845.84  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199   1 MSEIVKVIGREIMDSRGNPTVEADVYLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLNAVGFINNEIADALK 80
Cdd:COG0148    1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  81 GQNALEQSAVDKVMLDLDGTENKEKLGANAILAVSLATAKAAAQFKKVELYEHIADLNGtpgvYSMPLPMMNIINGGEHA 160
Cdd:COG0148   81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNA----KTLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 161 DNSVDIQEFMIQPVGAENFREGLRMGAEVFHSLAKVLKADGHSTAVGDEGGFAPNLASNEAALAAIKTAVANAGYELGKD 240
Cdd:COG0148  157 DNNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 241 ITLAMDCAASEFYDKeaNIYDLKGEGKKFTSEEFNYFLKDLTEQYPIVSIEDGLDESDWDGFAHQTKLMGDKIQLVGDDL 320
Cdd:COG0148  237 IALALDVAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDL 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 321 FVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDATIADLAVGTAAGQIKTGSLSR 400
Cdd:COG0148  315 FVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSR 394

                        410       420       430
                 ....*....|....*....|....*....|.
gi 658751199 401 SDRVAKYNQLLRIEEALGSKAPYNGLKEVKG 431
Cdd:COG0148  395 SERVAKYNQLLRIEEELGDAARYAGRSAFKR 425
eno PRK00077
enolase; Provisional
 1-432 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 814.32  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199   1 MSEIVKVIGREIMDSRGNPTVEADVYLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLNAVGFINNEIADALK 80
Cdd:PRK00077   1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  81 GQNALEQSAVDKVMLDLDGTENKEKLGANAILAVSLATAKAAAQFKKVELYEHIadlnGTPGVYSMPLPMMNIINGGEHA 160
Cdd:PRK00077  81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYL----GGPNAKVLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 161 DNSVDIQEFMIQPVGAENFREGLRMGAEVFHSLAKVLKADGHSTAVGDEGGFAPNLASNEAALAAIKTAVANAGYELGKD 240
Cdd:PRK00077 157 DNNVDIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 241 ITLAMDCAASEFYDKEanIYDLKGEGkkFTSEEFNYFLKDLTEQYPIVSIEDGLDESDWDGFAHQTKLMGDKIQLVGDDL 320
Cdd:PRK00077 237 IALALDCAASEFYKDG--KYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDL 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 321 FVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDATIADLAVGTAAGQIKTGSLSR 400
Cdd:PRK00077 313 FVTNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSR 392

                        410       420       430
                 ....*....|....*....|....*....|..
gi 658751199 401 SDRVAKYNQLLRIEEALGSKAPYNGLKEVKGQ 432
Cdd:PRK00077 393 SERIAKYNQLLRIEEELGDAARYAGKKAFKNL 424
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 4-432 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 712.98  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199    4 IVKVIGREIMDSRGNPTVEADVYLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLNAVGFINNEIADALKGQN 83
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199   84 ALEQSAVDKVMLDLDGTENKEKLGANAILAVSLATAKAAAQFKKVELYEHIADLNGtpgvYSMPLPMMNIINGGEHADNS 163
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNA----YVLPVPMMNIINGGAHADNN 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  164 VDIQEFMIQPVGAENFREGLRMGAEVFHSLAKVLKADGHSTAVGDEGGFAPNLASNEAALAAIKTAVANAGYELGKDITL 243
Cdd:TIGR01060 157 LDFQEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVAL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  244 AMDCAASEFYDKEANIYDLKGEGKKFTSEEFNYFLKDLTEQYPIVSIEDGLDESDWDGFAHQTKLMGDKIQLVGDDLFVT 323
Cdd:TIGR01060 237 ALDCAASEFYDEEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVT 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  324 NTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDATIADLAVGTAAGQIKTGSLSRSDR 403
Cdd:TIGR01060 317 NTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSER 396

                         410       420
                  ....*....|....*....|....*....
gi 658751199  404 VAKYNQLLRIEEALGSKAPYNGLKEVKGQ 432
Cdd:TIGR01060 397 IAKYNQLLRIEEELGDSARYAGKNSFYRF 425
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 6-415 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 704.24  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199   6 KVIGREIMDSRGNPTVEADVYLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLNAVGFINNEIADALKGQNAL 85
Cdd:cd03313    1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  86 EQSAVDKVMLDLDGTENKEKLGANAILAVSLATAKAAAQFKKVELYEHIADLNGtpgvYSMPLPMMNIINGGEHADNSVD 165
Cdd:cd03313   81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAA----YVLPVPMFNVINGGAHAGNKLD 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 166 IQEFMIQPVGAENFREGLRMGAEVFHSLAKVLKADG--HSTAVGDEGGFAPNLASNEAALAAIKTAVANAGYELGKDITL 243
Cdd:cd03313  157 FQEFMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAI 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 244 AMDCAASEFYDKEANIYDlKGEGKKFTSEEFNYFLKDLTEQYPIVSIEDGLDESDWDGFAHQTKLMGDKIQLVGDDLFVT 323
Cdd:cd03313  237 ALDVAASEFYDEGKYVYD-SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVT 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 324 NTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDATIADLAVGTAAGQIKTGSLSRSDR 403
Cdd:cd03313  316 NPERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSER 395

                        410
                 ....*....|..
gi 658751199 404 VAKYNQLLRIEE 415
Cdd:cd03313  396 TAKYNQLLRIEE 407
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
144-432 8.65e-160

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 452.32  E-value: 8.65e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  144 YSMPLPMMNIINGGEHADNSVDIQEFMIQPVGAENFREGLRMGAEVFHSLAKVLKADGHS--TAVGDEGGFAPNLASNEA 221
Cdd:pfam00113   2 YVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGQsaTNVGDEGGFAPNLQSNKE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  222 ALAAIKTAVANAGYELgkDITLAMDCAASEFYDKEANIYDLKGEG------KKFTSEEFNYFLKDLTEQYPIVSIEDGLD 295
Cdd:pfam00113  82 ALDLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPFD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  296 ESDWDGFAHQTKLMGDKIQLVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGE 375
Cdd:pfam00113 160 EDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGE 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 658751199  376 TEDATIADLAVGTAAGQIKTGSLSRSDRVAKYNQLLRIEEALGSKAPYNGLKEVKGQ 432
Cdd:pfam00113 240 TEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-431 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 845.84  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199   1 MSEIVKVIGREIMDSRGNPTVEADVYLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLNAVGFINNEIADALK 80
Cdd:COG0148    1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  81 GQNALEQSAVDKVMLDLDGTENKEKLGANAILAVSLATAKAAAQFKKVELYEHIADLNGtpgvYSMPLPMMNIINGGEHA 160
Cdd:COG0148   81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNA----KTLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 161 DNSVDIQEFMIQPVGAENFREGLRMGAEVFHSLAKVLKADGHSTAVGDEGGFAPNLASNEAALAAIKTAVANAGYELGKD 240
Cdd:COG0148  157 DNNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 241 ITLAMDCAASEFYDKeaNIYDLKGEGKKFTSEEFNYFLKDLTEQYPIVSIEDGLDESDWDGFAHQTKLMGDKIQLVGDDL 320
Cdd:COG0148  237 IALALDVAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDL 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 321 FVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDATIADLAVGTAAGQIKTGSLSR 400
Cdd:COG0148  315 FVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSR 394

                        410       420       430
                 ....*....|....*....|....*....|.
gi 658751199 401 SDRVAKYNQLLRIEEALGSKAPYNGLKEVKG 431
Cdd:COG0148  395 SERVAKYNQLLRIEEELGDAARYAGRSAFKR 425
eno PRK00077
enolase; Provisional
 1-432 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 814.32  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199   1 MSEIVKVIGREIMDSRGNPTVEADVYLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLNAVGFINNEIADALK 80
Cdd:PRK00077   1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  81 GQNALEQSAVDKVMLDLDGTENKEKLGANAILAVSLATAKAAAQFKKVELYEHIadlnGTPGVYSMPLPMMNIINGGEHA 160
Cdd:PRK00077  81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYL----GGPNAKVLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 161 DNSVDIQEFMIQPVGAENFREGLRMGAEVFHSLAKVLKADGHSTAVGDEGGFAPNLASNEAALAAIKTAVANAGYELGKD 240
Cdd:PRK00077 157 DNNVDIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 241 ITLAMDCAASEFYDKEanIYDLKGEGkkFTSEEFNYFLKDLTEQYPIVSIEDGLDESDWDGFAHQTKLMGDKIQLVGDDL 320
Cdd:PRK00077 237 IALALDCAASEFYKDG--KYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDL 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 321 FVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDATIADLAVGTAAGQIKTGSLSR 400
Cdd:PRK00077 313 FVTNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSR 392

                        410       420       430
                 ....*....|....*....|....*....|..
gi 658751199 401 SDRVAKYNQLLRIEEALGSKAPYNGLKEVKGQ 432
Cdd:PRK00077 393 SERIAKYNQLLRIEEELGDAARYAGKKAFKNL 424
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 4-432 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 712.98  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199    4 IVKVIGREIMDSRGNPTVEADVYLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLNAVGFINNEIADALKGQN 83
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199   84 ALEQSAVDKVMLDLDGTENKEKLGANAILAVSLATAKAAAQFKKVELYEHIADLNGtpgvYSMPLPMMNIINGGEHADNS 163
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNA----YVLPVPMMNIINGGAHADNN 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  164 VDIQEFMIQPVGAENFREGLRMGAEVFHSLAKVLKADGHSTAVGDEGGFAPNLASNEAALAAIKTAVANAGYELGKDITL 243
Cdd:TIGR01060 157 LDFQEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVAL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  244 AMDCAASEFYDKEANIYDLKGEGKKFTSEEFNYFLKDLTEQYPIVSIEDGLDESDWDGFAHQTKLMGDKIQLVGDDLFVT 323
Cdd:TIGR01060 237 ALDCAASEFYDEEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVT 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  324 NTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDATIADLAVGTAAGQIKTGSLSRSDR 403
Cdd:TIGR01060 317 NTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSER 396

                         410       420
                  ....*....|....*....|....*....
gi 658751199  404 VAKYNQLLRIEEALGSKAPYNGLKEVKGQ 432
Cdd:TIGR01060 397 IAKYNQLLRIEEELGDSARYAGKNSFYRF 425
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 6-415 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 704.24  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199   6 KVIGREIMDSRGNPTVEADVYLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLNAVGFINNEIADALKGQNAL 85
Cdd:cd03313    1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  86 EQSAVDKVMLDLDGTENKEKLGANAILAVSLATAKAAAQFKKVELYEHIADLNGtpgvYSMPLPMMNIINGGEHADNSVD 165
Cdd:cd03313   81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAA----YVLPVPMFNVINGGAHAGNKLD 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 166 IQEFMIQPVGAENFREGLRMGAEVFHSLAKVLKADG--HSTAVGDEGGFAPNLASNEAALAAIKTAVANAGYELGKDITL 243
Cdd:cd03313  157 FQEFMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAI 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 244 AMDCAASEFYDKEANIYDlKGEGKKFTSEEFNYFLKDLTEQYPIVSIEDGLDESDWDGFAHQTKLMGDKIQLVGDDLFVT 323
Cdd:cd03313  237 ALDVAASEFYDEGKYVYD-SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVT 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 324 NTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDATIADLAVGTAAGQIKTGSLSRSDR 403
Cdd:cd03313  316 NPERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSER 395

                        410
                 ....*....|..
gi 658751199 404 VAKYNQLLRIEE 415
Cdd:cd03313  396 TAKYNQLLRIEE 407
PTZ00081 PTZ00081
enolase; Provisional
 1-425 0e+00

enolase; Provisional


Pssm-ID: 240259 [Multi-domain]  Cd Length: 439  Bit Score: 567.76  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199   1 MSEIVKVIGREIMDSRGNPTVEADVYLADGSWgRAAAPSGASTGTREALELRDGDKARYLGKGVLNAVGFINNEIADALK 80
Cdd:PTZ00081   1 MSTIKSIKAREILDSRGNPTVEVDLTTEKGVF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  81 GQNALEQSAVDKVMLD-LDGTEN-----KEKLGANAILAVSLATAKAAAQFKKVELYEHIADLNGTPGV-YSMPLPMMNI 153
Cdd:PTZ00081  80 GKDVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQLAGKPTDkFVLPVPCFNV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 154 INGGEHADNSVDIQEFMIQPVGAENFREGLRMGAEVFHSLAKVLKAD-GHS-TAVGDEGGFAPNLASNEAALAAIKTAVA 231
Cdd:PTZ00081 160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKKyGLDaTNVGDEGGFAPNIKDPEEALDLLVEAIK 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 232 NAGYElGKdITLAMDCAASEFYDKEANIYDL------KGEGKKFTSEEFNYFLKDLTEQYPIVSIEDGLDESDWDGFAHQ 305
Cdd:PTZ00081 240 KAGYE-GK-VKICMDVAASEFYDKEKKVYDLdfknpnNDKSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAKL 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 306 TKLMGDKIQLVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDATIADLA 385
Cdd:PTZ00081 318 TAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADLV 397

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 658751199 386 VGTAAGQIKTGSLSRSDRVAKYNQLLRIEEALGSKAPYNG 425
Cdd:PTZ00081 398 VGLGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAG 437
PLN00191 PLN00191
enolase
 1-425 0e+00

enolase


Pssm-ID: 215095 [Multi-domain]  Cd Length: 457  Bit Score: 541.61  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199   1 MSEIVKVIGREIMDSRGNPTVEADVYLADGsWGRAAAPSGASTGTREALELRDGDKaRYLGKGVLNAVGFINNEIADALK 80
Cdd:PLN00191  25 MATITKVKARQIIDSRGNPTVEVDLHTSKG-MFRAAVPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPALI 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  81 GQNALEQSAVDKVMLDLDGTENKEKLGANAILAVSLATAKAAAQFKKVELYEHIADLNGTPGVySMPLPMMNIINGGEHA 160
Cdd:PLN00191 103 GMDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHIADLAGNKKL-VLPVPAFNVINGGSHA 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 161 DNSVDIQEFMIQPVGAENFREGLRMGAEVFHSLAKVLKAD--GHSTAVGDEGGFAPNLASNEAALAAIKTAVANAGYElG 238
Cdd:PLN00191 182 GNKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYT-G 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 239 KdITLAMDCAASEFYDKEaNIYDL------KGEGKKFTSEEFNYFLKDLTEQYPIVSIEDGLDESDWDGFAHQTKLmgDK 312
Cdd:PLN00191 261 K-IKIGMDVAASEFYTKD-KKYDLdfkeenNDGSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSL--ED 336

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 313 IQLVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDATIADLAVGTAAGQ 392
Cdd:PLN00191 337 VQIVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQ 416

                        410       420       430
                 ....*....|....*....|....*....|...
gi 658751199 393 IKTGSLSRSDRVAKYNQLLRIEEALGSKAPYNG 425
Cdd:PLN00191 417 IKTGAPCRSERLAKYNQLLRIEEELGDEAVYAG 449
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
144-432 8.65e-160

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 452.32  E-value: 8.65e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  144 YSMPLPMMNIINGGEHADNSVDIQEFMIQPVGAENFREGLRMGAEVFHSLAKVLKADGHS--TAVGDEGGFAPNLASNEA 221
Cdd:pfam00113   2 YVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGQsaTNVGDEGGFAPNLQSNKE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  222 ALAAIKTAVANAGYELgkDITLAMDCAASEFYDKEANIYDLKGEG------KKFTSEEFNYFLKDLTEQYPIVSIEDGLD 295
Cdd:pfam00113  82 ALDLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPFD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  296 ESDWDGFAHQTKLMGDKIQLVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGE 375
Cdd:pfam00113 160 EDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGE 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 658751199  376 TEDATIADLAVGTAAGQIKTGSLSRSDRVAKYNQLLRIEEALGSKAPYNGLKEVKGQ 432
Cdd:pfam00113 240 TEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
Enolase_N pfam03952
Enolase, N-terminal domain;
4-134 1.08e-80

Enolase, N-terminal domain;


Pssm-ID: 461105 [Multi-domain]  Cd Length: 131  Bit Score: 244.59  E-value: 1.08e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199    4 IVKVIGREIMDSRGNPTVEADVYLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLNAVGFINNEIADALKGQN 83
Cdd:pfam03952   1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 658751199   84 ALEQSAVDKVMLDLDGTENKEKLGANAILAVSLATAKAAAQFKKVELYEHI 134
Cdd:pfam03952  81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
PRK08350 PRK08350
hypothetical protein; Provisional
 1-420 2.89e-17

hypothetical protein; Provisional


Pssm-ID: 169397 [Multi-domain]  Cd Length: 341  Bit Score: 82.55  E-value: 2.89e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199   1 MSEIVKVIGREIMDSRGNPTVEADVyLADGSWGRAAAPSgastgtrealelrDGDKARYLGKGvLNAVGFINNEIADALK 80
Cdd:PRK08350   1 MTVIENIIGRVAVLRGGKYSVEVDV-ITDSGFGRFAAPI-------------DENPSLYIAEA-HRAVSEVDEIIGPELI 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199  81 GQNALEQSAVDKVMLDLDGTENKEKLGANAILAVSLATAKAAAQFKKVELYEHIADLNGTpgvySMPLPMMNIINgGEHA 160
Cdd:PRK08350  66 GFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYIGGTFTT----ELPVPILEFAE-DENF 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 161 DNSVDIQEFMiqpvgaenfreglrMGAEVFHSLAKVLKadghstavgdeggfapnlASNEAALAAIKTAVANAGYELGKD 240
Cdd:PRK08350 141 EYYVLVRDLM--------------EITDVVDAVNKILE------------------NSKEVSLEGLSKASEKAGDELGLE 188

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 241 ITLAMdcaasefydkeaniydlkGEGKKFTSEEfnyfLKDLTEQYPIVSIED-GLDESDWDGFAHQTKLMGDkiqlvGDD 319
Cdd:PRK08350 189 VALGI------------------AQKREMETEK----VLNLVEDNNIAYIKPiGDEELFLELIAGTHGVFID-----GEY 241

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 320 LFVTNTKILKRgidngIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDATIADLAVGTAAGQIktgsLS 399
Cdd:PRK08350 242 LFRTRNILDRR-----YYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLRCPAM----LI 312

                        410       420
                 ....*....|....*....|.
gi 658751199 400 RSDRVAKYNQLLRIEEALGSK 420
Cdd:PRK08350 313 HKDSVEKINELNRIAEDLGER 333
enolase_like cd00308
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ...
 217-388 1.33e-11

Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.


Pssm-ID: 238188 [Multi-domain]  Cd Length: 229  Bit Score: 63.89  E-value: 1.33e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 217 ASNEAALAAIKTAVanagyelGKDITLAMDCAASEFYdKEAniydLKgegkkftseefnyFLKDLtEQYPIVSIEDGLDE 296
Cdd:cd00308   78 YGSIERVRAVREAF-------GPDARLAVDANGAWTP-KEA----IR-------------LIRAL-EKYGLAWIEEPCAP 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 297 SDWDGFAHQTKLMGdkIQLVGDDLFVTNTKILkRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSG-E 375
Cdd:cd00308  132 DDLEGYAALRRRTG--IPIAADESVTTVDDAL-EALELGAVDILQIKPTRVGGLTESRRAADLAEAFGIRVMVHGTLEsS 208

                        170
                 ....*....|...
gi 658751199 376 TEDATIADLAVGT 388
Cdd:cd00308  209 IGTAAALHLAAAL 221
PTZ00378 PTZ00378
hypothetical protein; Provisional
 107-420 1.44e-09

hypothetical protein; Provisional


Pssm-ID: 173571 [Multi-domain]  Cd Length: 518  Bit Score: 59.89  E-value: 1.44e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 107 GANAIL-AVSLATAKAAAQFKKVELYEHIADLNGTPG---VYSMPLPMMNIINGGEHADNSVDIQEFMIQPVGAEN--FR 180
Cdd:PTZ00378 146 VGSAVQwALSIVASLAAARCRSVPLFQYLRALFGSLTsveTFSMPQLCITFFGPGNPSTARLALKSVLFSPVMPSGtvLR 225

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 181 EGLRMGAEVFHSLAKVlkadgHSTAVGDEGGFAPNLASNEA-ALAAIKTAVANAGYELGKDITLAMDCAASEFYDKEANI 259
Cdd:PTZ00378 226 ERMQKIFAAFHHFCQS-----HNSSVRSDGSLHWDGFANLTdAVKLATEALRAVQLTPGTDVCLGLRMAASTTRVPATAV 300

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 260 YDL------KGEGKKF----------TSEEFNYFLKDLTEQYP--IVSIEDglDESDWDGFAHQTKLM--GDKIQLVGDD 319
Cdd:PTZ00378 301 ADGgawkeaKDDCEVLyslfpgepdvTGDQLSEYVREQLQAVPdiVVYVED--THCDEDTFGLQRLQAalGDSIVLSGVD 378

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658751199 320 LFV-TNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAK-DAGFTVVISHRSGETEDATIADLAVGTAAGQIKTGS 397
Cdd:PTZ00378 379 VYArSEYKKVESGLRGLWTSNIVLNPCAIGTLSDVVEIVRAVGeDEGRAVTVLVQTLAGNAATAAHLAVAMGARFLCSGG 458

                        330       340
                 ....*....|....*....|...
gi 658751199 398 LSRSDRVAKYNQLLRIEEALGSK 420
Cdd:PTZ00378 459 LFSAHQCEVVSQLASRQDELTHS 481
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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