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Conserved domains on  [gi|658927403|ref|WP_029789237|]
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MULTISPECIES: GIY-YIG nuclease family protein [Vibrio]

Protein Classification

GIY-YIG nuclease family protein( domain architecture ID 10603114)

GIY-YIG nuclease family protein is involved in many cellular processes, including DNA repair and recombination, transfer of mobile genetic elements, and restriction of incoming foreign DNA; similar to Acanthamoeba polyphaga mimivirus protein R9 and protein R10

CATH:  3.40.1440.10
Gene Ontology:  GO:0004518
PubMed:  16646971
SCOP:  3000597

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MUG113 pfam13455
Meiotically up-regulated gene 113; This is a family of fungal proteins found to be ...
 311-399 9.17e-14

Meiotically up-regulated gene 113; This is a family of fungal proteins found to be up-regulated in meiosis.


:

Pssm-ID: 372608  Cd Length: 73  Bit Score: 65.77  E-value: 9.17e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658927403  311 YKVGFTDgNVEDRIKYAEKDKTFleaPVRIVMTTECYNiDAHKLETLVHGFLGKQRLNVTlkghdgqtynpREWFHVPLA 390
Cdd:pfam13455   1 YKIGRTR-NVEKRLKELNSQSPF---KFDVVASYESTN-DARKLERLLHRELKEYRLNGG-----------NEWFKLNLE 64


                  ....*....
gi 658927403  391 TVLEVIKHI 399
Cdd:pfam13455  65 QLKEVVKRI 73
 
Name Accession Description Interval E-value
MUG113 pfam13455
Meiotically up-regulated gene 113; This is a family of fungal proteins found to be ...
 311-399 9.17e-14

Meiotically up-regulated gene 113; This is a family of fungal proteins found to be up-regulated in meiosis.


Pssm-ID: 372608  Cd Length: 73  Bit Score: 65.77  E-value: 9.17e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658927403  311 YKVGFTDgNVEDRIKYAEKDKTFleaPVRIVMTTECYNiDAHKLETLVHGFLGKQRLNVTlkghdgqtynpREWFHVPLA 390
Cdd:pfam13455   1 YKIGRTR-NVEKRLKELNSQSPF---KFDVVASYESTN-DARKLERLLHRELKEYRLNGG-----------NEWFKLNLE 64


                  ....*....
gi 658927403  391 TVLEVIKHI 399
Cdd:pfam13455  65 QLKEVVKRI 73
T5orf172 smart00974
This entry represents the putative helicase A859L;
308-397 1.81e-12

This entry represents the putative helicase A859L;


Pssm-ID: 214947  Cd Length: 80  Bit Score: 62.35  E-value: 1.81e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658927403   308 ANLYKVGFTDGNVEDRIK-YAEKDKTFLEAPVRIVMTTEcyniDAHKLETLVHGFLGKQrlnvtlkghdGQTYNPREWFH 386
Cdd:smart00974   4 EGLVKIGYTTRDVERRLKeLSPTASVPLLFEVHALIEVE----DARKLEALLHRALADA----------GRRNPHREWFR 69

                           90
                   ....*....|.
gi 658927403   387 VPLATVLEVIK 397
Cdd:smart00974  70 LSLEEVKEVLK 80
 
Name Accession Description Interval E-value
MUG113 pfam13455
Meiotically up-regulated gene 113; This is a family of fungal proteins found to be ...
 311-399 9.17e-14

Meiotically up-regulated gene 113; This is a family of fungal proteins found to be up-regulated in meiosis.


Pssm-ID: 372608  Cd Length: 73  Bit Score: 65.77  E-value: 9.17e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658927403  311 YKVGFTDgNVEDRIKYAEKDKTFleaPVRIVMTTECYNiDAHKLETLVHGFLGKQRLNVTlkghdgqtynpREWFHVPLA 390
Cdd:pfam13455   1 YKIGRTR-NVEKRLKELNSQSPF---KFDVVASYESTN-DARKLERLLHRELKEYRLNGG-----------NEWFKLNLE 64


                  ....*....
gi 658927403  391 TVLEVIKHI 399
Cdd:pfam13455  65 QLKEVVKRI 73
T5orf172 pfam10544
T5orf172 domain; This domain was identified by Iyer and colleagues.
 289-399 1.10e-13

T5orf172 domain; This domain was identified by Iyer and colleagues.


Pssm-ID: 463143  Cd Length: 99  Bit Score: 66.72  E-value: 1.10e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658927403  289 GMVYVLATKSsesvldpYKANLYKVGFTDgNVEDRIKYAEKDKTFLEAPVRIVMTTECYNI-DAHKLETLVHGFLGKQRL 367
Cdd:pfam10544   1 GYIYILTNPS-------NPGLIFKIGRTS-NLQRRLRELSKSSTSVPFEFSVIYEIKVRKVpNAFRLERLIHKELADFRY 72

                          90       100       110
                  ....*....|....*....|....*....|..
gi 658927403  368 NVTLKGHdgqtynPREWFHVPLATVLEVIKHI 399
Cdd:pfam10544  73 RVNCPCG------HREWFEVSLEEVDEIVKRI 98
T5orf172 smart00974
This entry represents the putative helicase A859L;
308-397 1.81e-12

This entry represents the putative helicase A859L;


Pssm-ID: 214947  Cd Length: 80  Bit Score: 62.35  E-value: 1.81e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658927403   308 ANLYKVGFTDGNVEDRIK-YAEKDKTFLEAPVRIVMTTEcyniDAHKLETLVHGFLGKQrlnvtlkghdGQTYNPREWFH 386
Cdd:smart00974   4 EGLVKIGYTTRDVERRLKeLSPTASVPLLFEVHALIEVE----DARKLEALLHRALADA----------GRRNPHREWFR 69

                           90
                   ....*....|.
gi 658927403   387 VPLATVLEVIK 397
Cdd:smart00974  70 LSLEEVKEVLK 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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