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Conserved domains on  [gi|662109332|ref|WP_030064839|]
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MULTISPECIES: alpha/beta hydrolase [Staphylococcus]

Protein Classification

alpha/beta hydrolase( domain architecture ID 12114401)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

CATH:  3.40.50.1820
EC:  3.-.-.-
Gene Ontology:  GO:0016787
PubMed:  12369917|19508187|37582413

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 29-287 5.89e-64

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


:

Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 201.67  E-value: 5.89e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332   29 GIIHLFHGMAEHMDRYDELVNALNIQGYDVLRHNHRGHGKDidEVERGHFESMSQIADDAYEIVETLYGTELKVPYVVLG 108
Cdd:pfam12146   5 AVVVLVHGLGEHSGRYAHLADALAAQGFAVYAYDHRGHGRS--DGKRGHVPSFDDYVDDLDTFVDKIREEHPGLPLFLLG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  109 HSMGSIIARLFVMRYPEFADGLILTGTGMFPKWKgvPATFALKLITMILGKRRRvnwvnklvnksfNKRISNPLtESDWI 188
Cdd:pfam12146  83 HSMGGLIAALYALRYPDKVDGLILSAPALKIKPY--LAPPILKLLAKLLGKLFP------------RLRVPNNL-LPDSL 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  189 STRRDEVEKFVKDEYCGFKVSNQLIYQTVKFMMltiepKCLDKLNK-QLPILLISGKEDPFGDYGKGIkqlgKLYKKSGI 267
Cdd:pfam12146 148 SRDPEVVAAYAADPLVHGGISARTLYELLDAGE-----RLLRRAAAiTVPLLLLHGGADRVVDPAGSR----EFYERAGS 218

                         250       260
                  ....*....|....*....|
gi 662109332  268 KHITVQLYKNKRHEILFEDD 287
Cdd:pfam12146 219 TDKTLKLYPGLYHELLNEPD 238
 
Name Accession Description Interval E-value
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 29-287 5.89e-64

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 201.67  E-value: 5.89e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332   29 GIIHLFHGMAEHMDRYDELVNALNIQGYDVLRHNHRGHGKDidEVERGHFESMSQIADDAYEIVETLYGTELKVPYVVLG 108
Cdd:pfam12146   5 AVVVLVHGLGEHSGRYAHLADALAAQGFAVYAYDHRGHGRS--DGKRGHVPSFDDYVDDLDTFVDKIREEHPGLPLFLLG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  109 HSMGSIIARLFVMRYPEFADGLILTGTGMFPKWKgvPATFALKLITMILGKRRRvnwvnklvnksfNKRISNPLtESDWI 188
Cdd:pfam12146  83 HSMGGLIAALYALRYPDKVDGLILSAPALKIKPY--LAPPILKLLAKLLGKLFP------------RLRVPNNL-LPDSL 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  189 STRRDEVEKFVKDEYCGFKVSNQLIYQTVKFMMltiepKCLDKLNK-QLPILLISGKEDPFGDYGKGIkqlgKLYKKSGI 267
Cdd:pfam12146 148 SRDPEVVAAYAADPLVHGGISARTLYELLDAGE-----RLLRRAAAiTVPLLLLHGGADRVVDPAGSR----EFYERAGS 218

                         250       260
                  ....*....|....*....|
gi 662109332  268 KHITVQLYKNKRHEILFEDD 287
Cdd:pfam12146 219 TDKTLKLYPGLYHELLNEPD 238
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
1-301 7.10e-43

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 147.07  E-value: 7.10e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332   1 MSQSQFKITVEDGTMIEVKVDKAKKNTIGIIHLFHGMAEHMDRYDELVNALNIQGYDVLRHNHRGHGKdiDEVERGHFES 80
Cdd:COG2267    1 MTRRLVTLPTRDGLRLRGRRWRPAGSPRGTVVLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGR--SDGPRGHVDS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  81 MSQIADDAYEIVETLyGTELKVPYVVLGHSMGSIIARLFVMRYPEFADGLILTGTgmfpkwkgvpatfalklitmilgkr 160
Cdd:COG2267   79 FDDYVDDLRAALDAL-RARPGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAP------------------------- 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332 161 rrvnwvnklvnksfnkrisnpltesdwistrrdeveKFVKDEYCGFkvsnqliyqTVKFMMLTIEPKCLDKLnkQLPILL 240
Cdd:COG2267  133 ------------------------------------AYRADPLLGP---------SARWLRALRLAEALARI--DVPVLV 165

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 662109332 241 ISGKEDPFGDyGKGIKQLGKLYKksgiKHITVQLYKNKRHEILFEDDYQTTWQHMFEWIEK 301
Cdd:COG2267  166 LHGGADRVVP-PEAARRLAARLS----PDVELVLLPGARHELLNEPAREEVLAAILAWLER 221
PHA02857 PHA02857
monoglyceride lipase; Provisional
 30-309 9.18e-16

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 75.69  E-value: 9.18e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  30 IIHLFHGMAEHMDRYDELVNALNIQGYDVLRHNHRGHGKDidEVERGHFESMSQIADDAYEIVETLYGTELKVPYVVLGH 109
Cdd:PHA02857  27 LVFISHGAGEHSGRYEELAENISSLGILVFSHDHIGHGRS--NGEKMMIDDFGVYVRDVVQHVVTIKSTYPGVPVFLLGH 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332 110 SMGSIIARLFVMRYPEFADGLILtgtgMFPKWKGVPATFALKLITMILGkrrrVNWVNKLVNKSFNKRISNPLtesdwis 189
Cdd:PHA02857 105 SMGATISILAAYKNPNLFTAMIL----MSPLVNAEAVPRLNLLAAKLMG----IFYPNKIVGKLCPESVSRDM------- 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332 190 trrDEVEKFVKDEY-CGFKVSNQLIYQtvkfmMLTIEPKCLDKLNK-QLPILLISGKEDPFGDYgkgikQLGKLYKKSGI 267
Cdd:PHA02857 170 ---DEVYKYQYDPLvNHEKIKAGFASQ-----VLKATNKVRKIIPKiKTPILILQGTNNEISDV-----SGAYYFMQHAN 236

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 662109332 268 KHITVQLYKNKRHEILFEDDyqTTWQHMFEWIEKQILKKNKV 309
Cdd:PHA02857 237 CNREIKIYEGAKHHLHKETD--EVKKSVMKEIETWIFNRVKV 276
 
Name Accession Description Interval E-value
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 29-287 5.89e-64

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 201.67  E-value: 5.89e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332   29 GIIHLFHGMAEHMDRYDELVNALNIQGYDVLRHNHRGHGKDidEVERGHFESMSQIADDAYEIVETLYGTELKVPYVVLG 108
Cdd:pfam12146   5 AVVVLVHGLGEHSGRYAHLADALAAQGFAVYAYDHRGHGRS--DGKRGHVPSFDDYVDDLDTFVDKIREEHPGLPLFLLG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  109 HSMGSIIARLFVMRYPEFADGLILTGTGMFPKWKgvPATFALKLITMILGKRRRvnwvnklvnksfNKRISNPLtESDWI 188
Cdd:pfam12146  83 HSMGGLIAALYALRYPDKVDGLILSAPALKIKPY--LAPPILKLLAKLLGKLFP------------RLRVPNNL-LPDSL 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  189 STRRDEVEKFVKDEYCGFKVSNQLIYQTVKFMMltiepKCLDKLNK-QLPILLISGKEDPFGDYGKGIkqlgKLYKKSGI 267
Cdd:pfam12146 148 SRDPEVVAAYAADPLVHGGISARTLYELLDAGE-----RLLRRAAAiTVPLLLLHGGADRVVDPAGSR----EFYERAGS 218

                         250       260
                  ....*....|....*....|
gi 662109332  268 KHITVQLYKNKRHEILFEDD 287
Cdd:pfam12146 219 TDKTLKLYPGLYHELLNEPD 238
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
1-301 7.10e-43

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 147.07  E-value: 7.10e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332   1 MSQSQFKITVEDGTMIEVKVDKAKKNTIGIIHLFHGMAEHMDRYDELVNALNIQGYDVLRHNHRGHGKdiDEVERGHFES 80
Cdd:COG2267    1 MTRRLVTLPTRDGLRLRGRRWRPAGSPRGTVVLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGR--SDGPRGHVDS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  81 MSQIADDAYEIVETLyGTELKVPYVVLGHSMGSIIARLFVMRYPEFADGLILTGTgmfpkwkgvpatfalklitmilgkr 160
Cdd:COG2267   79 FDDYVDDLRAALDAL-RARPGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAP------------------------- 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332 161 rrvnwvnklvnksfnkrisnpltesdwistrrdeveKFVKDEYCGFkvsnqliyqTVKFMMLTIEPKCLDKLnkQLPILL 240
Cdd:COG2267  133 ------------------------------------AYRADPLLGP---------SARWLRALRLAEALARI--DVPVLV 165

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 662109332 241 ISGKEDPFGDyGKGIKQLGKLYKksgiKHITVQLYKNKRHEILFEDDYQTTWQHMFEWIEK 301
Cdd:COG2267  166 LHGGADRVVP-PEAARRLAARLS----PDVELVLLPGARHELLNEPAREEVLAAILAWLER 221
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 33-287 1.58e-18

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 82.94  E-value: 1.58e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332   33 LFHGMAEHMDRYDELVNALNIQGYDVLRHNHRGHGKDIDEVERGHFESMSqIADDAYEIVETLYGTELkvpyVVLGHSMG 112
Cdd:pfam00561   5 LLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQDDYRTDD-LAEDLEYILEALGLEKV----NLVGHSMG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  113 SIIARLFVMRYPEFADGLILTGTGM---------------FPKWK-GVPATFALKLITMILGKRRRVNWVNKLVNKSFNK 176
Cdd:pfam00561  80 GLIALAYAAKYPDRVKALVLLGALDppheldeadrfilalFPGFFdGFVADFAPNPLGRLVAKLLALLLLRLRLLKALPL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  177 RISNPLTESDWISTRRDevekfvkdeycGFKVSNQLIYQTVKFMmltiepKCLDKLNKqlPILLISGKEDPFGDYgKGIK 256
Cdd:pfam00561 160 LNKRFPSGDYALAKSLV-----------TGALLFIETWSTELRA------KFLGRLDE--PTLIIWGDQDPLVPP-QALE 219

                         250       260       270
                  ....*....|....*....|....*....|.
gi 662109332  257 QLGKLykksgIKHITVQLYKNKRHEILFEDD 287
Cdd:pfam00561 220 KLAQL-----FPNARLVVIPDAGHFAFLEGP 245
PHA02857 PHA02857
monoglyceride lipase; Provisional
 30-309 9.18e-16

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 75.69  E-value: 9.18e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  30 IIHLFHGMAEHMDRYDELVNALNIQGYDVLRHNHRGHGKDidEVERGHFESMSQIADDAYEIVETLYGTELKVPYVVLGH 109
Cdd:PHA02857  27 LVFISHGAGEHSGRYEELAENISSLGILVFSHDHIGHGRS--NGEKMMIDDFGVYVRDVVQHVVTIKSTYPGVPVFLLGH 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332 110 SMGSIIARLFVMRYPEFADGLILtgtgMFPKWKGVPATFALKLITMILGkrrrVNWVNKLVNKSFNKRISNPLtesdwis 189
Cdd:PHA02857 105 SMGATISILAAYKNPNLFTAMIL----MSPLVNAEAVPRLNLLAAKLMG----IFYPNKIVGKLCPESVSRDM------- 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332 190 trrDEVEKFVKDEY-CGFKVSNQLIYQtvkfmMLTIEPKCLDKLNK-QLPILLISGKEDPFGDYgkgikQLGKLYKKSGI 267
Cdd:PHA02857 170 ---DEVYKYQYDPLvNHEKIKAGFASQ-----VLKATNKVRKIIPKiKTPILILQGTNNEISDV-----SGAYYFMQHAN 236

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 662109332 268 KHITVQLYKNKRHEILFEDDyqTTWQHMFEWIEKQILKKNKV 309
Cdd:PHA02857 237 CNREIKIYEGAKHHLHKETD--EVKKSVMKEIETWIFNRVKV 276
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 1-134 3.71e-14

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 70.42  E-value: 3.71e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332   1 MSQSQFkITVeDGTMIEVKVDKAKKNTIgiiHLFHGMAEHMDRYDELVNALNiQGYDVLRHNHRGHGKDiDEVERGHfeS 80
Cdd:COG0596    1 MSTPRF-VTV-DGVRLHYREAGPDGPPV---VLLHGLPGSSYEWRPLIPALA-AGYRVIAPDLRGHGRS-DKPAGGY--T 71

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 662109332  81 MSQIADDAYEIVETLyGTElkvPYVVLGHSMGSIIARLFVMRYPEFADGLILTG 134
Cdd:COG0596   72 LDDLADDLAALLDAL-GLE---RVVLVGHSMGGMVALELAARHPERVAGLVLVD 121
PRK10749 PRK10749
lysophospholipase L2; Provisional
 30-141 4.79e-10

lysophospholipase L2; Provisional


Pssm-ID: 182697  Cd Length: 330  Bit Score: 59.63  E-value: 4.79e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  30 IIHLFHGMAEHMDRYDELVNALNIQGYDVLRHNHRGHGKD---IDEVERGHFESMSQIADDayeiVETLYGTELKV-PY- 104
Cdd:PRK10749  56 VVVICPGRIESYVKYAELAYDLFHLGYDVLIIDHRGQGRSgrlLDDPHRGHVERFNDYVDD----LAAFWQQEIQPgPYr 131

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 662109332 105 --VVLGHSMGSIIARLFVMRYPEFADGLILTGTgMF------PKW 141
Cdd:PRK10749 132 krYALAHSMGGAILTLFLQRHPGVFDAIALCAP-MFgivlplPSW 175
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
24-301 7.88e-07

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 49.17  E-value: 7.88e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  24 KKNTIGIIhLFHGMAEHMDRYDELVNALNIQGYDVLRHNHRGHGKDIDEVERGHFESMSQIADDAYEIVETLYGtelKVp 103
Cdd:COG1647   12 EGGRKGVL-LLHGFTGSPAEMRPLAEALAKAGYTVYAPRLPGHGTSPEDLLKTTWEDWLEDVEEAYEILKAGYD---KV- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332 104 yVVLGHSMGSIIARLFVMRYPEFaDGLILTGTGMFPKWKGVPATFALKLITmilgkrrrvnwvnklvnksfnkrisnplt 183
Cdd:COG1647   87 -IVIGLSMGGLLALLLAARYPDV-AGLVLLSPALKIDDPSAPLLPLLKYLA----------------------------- 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332 184 esDWISTRRDEVEKFVKDEYCGFKVSNQLIYQTVKFMMLTiePKCLDKLNKqlPILLISGKEDPFGDYgkgiKQLGKLYK 263
Cdd:COG1647  136 --RSLRGIGSDIEDPEVAEYAYDRTPLRALAELQRLIREV--RRDLPKITA--PTLIIQSRKDEVVPP----ESARYIYE 205

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 662109332 264 KSGIKHITVQLYKNKRHEILFEDDYQTTWQHMFEWIEK 301
Cdd:COG1647  206 RLGSPDKELVWLEDSGHVITLDKDREEVAEEILDFLER 243
PLN02652 PLN02652
hydrolase; alpha/beta fold family protein
 29-303 1.24e-06

hydrolase; alpha/beta fold family protein


Pssm-ID: 215352 [Multi-domain]  Cd Length: 395  Bit Score: 49.51  E-value: 1.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  29 GIIHLFHGMAEHMDRYDELVNALNIQGYDVLRHNHRGHGKdiDEVERGHFESMSQIADDAYEIVETLYGTELKVPYVVLG 108
Cdd:PLN02652 137 GILIIIHGLNEHSGRYLHFAKQLTSCGFGVYAMDWIGHGG--SDGLHGYVPSLDYVVEDTEAFLEKIRSENPGVPCFLFG 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332 109 HSMGSIIArLFVMRYPEFAD---GLILTGTGMFPKwKGVPATFALKLITMILGKRRRVNWVNKL---VNK---SFNKRIS 179
Cdd:PLN02652 215 HSTGGAVV-LKAASYPSIEDkleGIVLTSPALRVK-PAHPIVGAVAPIFSLVAPRFQFKGANKRgipVSRdpaALLAKYS 292

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332 180 NPLTESDWISTRrdevekfvkdeyCGFKVSNQLIYQTVKFMMLTIepkcldklnkqlPILLISGKEDPFGDygkgikQLG 259
Cdd:PLN02652 293 DPLVYTGPIRVR------------TGHEILRISSYLTRNFKSVTV------------PFMVLHGTADRVTD------PLA 342

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 662109332 260 K--LYKKSGIKHITVQLYKNKRHEILFEDDYQTTWQHMFEWIEKQI 303
Cdd:PLN02652 343 SqdLYNEAASRHKDIKLYDGFLHDLLFEPEREEVGRDIIDWMEKRL 388
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 33-120 7.10e-06

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 44.05  E-value: 7.10e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332  33 LFHGMAEHMDRYDELVNALNIQGYDVLRHNHRGHGKDIDEverghfeSMSQIADDAYEIVETlYGTElKVpyVVLGHSMG 112
Cdd:COG1075   10 LVHGLGGSAASWAPLAPRLRAAGYPVYALNYPSTNGSIED-------SAEQLAAFVDAVLAA-TGAE-KV--DLVGHSMG 78


                 ....*...
gi 662109332 113 SIIARLFV 120
Cdd:COG1075   79 GLVARYYL 86
COG4757 COG4757
Predicted alpha/beta hydrolase [General function prediction only];
1-152 9.93e-06

Predicted alpha/beta hydrolase [General function prediction only];


Pssm-ID: 443790 [Multi-domain]  Cd Length: 289  Bit Score: 46.42  E-value: 9.93e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332   1 MSQSQFKITVEDGTMIEVKVDKAKKNTIGIIhLFHG-MAEHMDRYDELVNALNIQGYDVLRHNHRGHGKDIDEVERGHFE 79
Cdd:COG4757    5 ASPESVTITAADGYPLAARLFPPAGPPRAVV-LINPaTGVPQRFYRPFARYLAERGFAVLTYDYRGIGLSRPGSLRGFDA 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 662109332  80 SMSQIA----DDAYEIVETLYGtelKVPYVVLGHSMGSIIARLfvMRYPEFADGLILTGTGmFPKWKGVPATFALKL 152
Cdd:COG4757   84 GYRDWGeldlPAVLDALRARFP---GLPLLLVGHSLGGQLLGL--APNAERVDRLVTVASG-SGYWRDYPPRRRLKV 154
GrsT COG3208
Surfactin synthase thioesterase subunit [Secondary metabolites biosynthesis, transport and ...
 65-116 5.37e-05

Surfactin synthase thioesterase subunit [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442441 [Multi-domain]  Cd Length: 237  Bit Score: 43.69  E-value: 5.37e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 662109332  65 GHGKDIDEVergHFESMSQIADDAYEIVETLygteLKVPYVVLGHSMGSIIA 116
Cdd:COG3208   42 GRGDRLGEP---PLTSLEELADDLAEELAPL----LDRPFALFGHSMGALLA 86
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
8-132 1.03e-04

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 42.70  E-value: 1.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332   8 ITVEDGTMIEVKVDKAKKNT-IGIIHLFHGMAEHMDR-YDELVNALNIQGYDVLRHNHRGHGKDIDEVERghfesmsQIA 85
Cdd:COG1506    2 FKSADGTTLPGWLYLPADGKkYPVVVYVHGGPGSRDDsFLPLAQALASRGYAVLAPDYRGYGESAGDWGG-------DEV 74

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 662109332  86 DDAYEIVETLygteLKVPYV------VLGHSMGSIIARLFVMRYPEFADGLIL 132
Cdd:COG1506   75 DDVLAAIDYL----AARPYVdpdrigIYGHSYGGYMALLAAARHPDRFKAAVA 123
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 33-165 2.80e-04

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 41.31  E-value: 2.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332   33 LFHGMAEHMDRYDELVNAlniqGYDVLRHNHRGHGKDIDEVErgHFESMSQIADdayeIVETLYGTElkvPYVVLGHSMG 112
Cdd:pfam12697   3 LVHGAGLSAAPLAALLAA----GVAVLAPDLPGHGSSSPPPL--DLADLADLAA----LLDELGAAR---PVVLVGHSLG 69

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 662109332  113 SIIARLFVMRYPefADGLILTGTGMFPKWkgvpATFALKLITMILGKRRRVNW 165
Cdd:pfam12697  70 GAVALAAAAAAL--VVGVLVAPLAAPPGL----LAALLALLARLGAALAAPAW 116
YheT COG0429
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
8-112 1.25e-03

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


Pssm-ID: 440198 [Multi-domain]  Cd Length: 323  Bit Score: 40.13  E-value: 1.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332   8 ITVEDGTMIEVKVDKAKKNTIGIIHLFHGMAEHMDR-Y-DELVNALNIQGYDVLRHNHRGHGKdidEVERghfesmSQIA 85
Cdd:COG0429   41 LELPDGDFVDLDWSDPPAPSKPLVVLLHGLEGSSDShYaRGLARALYARGWDVVRLNFRGCGG---EPNL------LPRL 111

                         90       100       110
                 ....*....|....*....|....*....|...
gi 662109332  86 ------DDAYEIVETLYGTELKVPYVVLGHSMG 112
Cdd:COG0429  112 yhsgdtEDLVWVLAHLRARYPYAPLYAVGFSLG 144
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 8-132 3.08e-03

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 38.36  E-value: 3.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662109332   8 ITVEDGTMI--EVKVDKAKKNTIGIIHLFHGMAEHMDRYDELVNALNIQGYDVLRHNHRGHGKdiDEVERGHFESMSQI- 84
Cdd:COG1073   15 FKSRDGIKLagDLYLPAGASKKYPAVVVAHGNGGVKEQRALYAQRLAELGFNVLAFDYRGYGE--SEGEPREEGSPERRd 92

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 662109332  85 ADDAYEIVETLYGtelkVPY---VVLGHSMGSIIARLFVMRYPEFAdGLIL 132
Cdd:COG1073   93 ARAAVDYLRTLPG----VDPeriGLLGISLGGGYALNAAATDPRVK-AVIL 138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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