|
Name |
Accession |
Description |
Interval |
E-value |
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
145-499 |
3.17e-59 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 200.55 E-value: 3.17e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 145 RVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVA 224
Cdd:COG5002 27 LLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 225 TMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLR-----MRQFITDASHELRTPLAAIQGY 299
Cdd:COG5002 107 LLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELErleqmRREFVANVSHELRTPLTSIRGY 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 300 AELTRQDSSDLPPTTEYALARIESEARRMTLLVdellllsrlsegEDL-------------ETEDLDLTDLV--INAVND 364
Cdd:COG5002 187 LELLLDGAADDPEERREYLEIILEEAERLSRLV------------NDLldlsrlesgelklEKEPVDLAELLeeVVEELR 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 365 AAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGpnapcVELSVTDDGPDIDPEI 444
Cdd:COG5002 255 PLAEEKGIELELDLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDDQ-----VRISVRDTGIGIPEED 329
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 685931000 445 LPHLFDRFVRASKSRS-NGSGHGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLP 499
Cdd:COG5002 330 LPRIFERFYRVDKSRSrETGGTGLGLAIVKHIVEAHGGRIWVESEPGKgTTFTITLP 386
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
267-503 |
9.18e-55 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 183.95 E-value: 9.18e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 267 ALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGE- 345
Cdd:COG2205 5 ALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLESGKl 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 346 DLETEDLDLTDLV--INAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTigITCHRTG 423
Cdd:COG2205 85 SLELEPVDLAELLeeAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTIT--ISARREG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 424 PNapcVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGsGHGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPMIE 502
Cdd:COG2205 163 DG---VRISVSDNGPGIPEEELERIFERFYRGDNSRGEG-GTGLGLAIVKRIVEAHGGTIWVESEPGGgTTFTVTLPLAE 238
|
.
gi 685931000 503 Q 503
Cdd:COG2205 239 S 239
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
173-500 |
3.16e-53 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 182.80 E-value: 3.16e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 173 LSLANQIIARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGI 252
Cdd:COG0642 1 LLLLLLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 253 VGHTLNRLLDNVDGALAHRV----DSDLRMRQFITDASHELRTPLAAIQGYAELTRQdssDLPPTTEYALARIESEARRM 328
Cdd:COG0642 81 LLLLLLLLLLLLLLLLLALLllleEANEAKSRFLANVSHELRTPLTAIRGYLELLLE---ELDEEQREYLETILRSADRL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 329 TLLVDELLLLSRLSEGE-DLETEDLDLTDLV--INAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWV 405
Cdd:COG0642 158 LRLINDLLDLSRLEAGKlELEPEPVDLAELLeeVVELFRPLAEEKGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAIK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 406 HTQPGVTVTIGITCHRTGpnapcVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGsGHGLGLAIVSSIVKAHRGSVTA 485
Cdd:COG0642 238 YTPEGGTVTVSVRREGDR-----VRISVEDTGPGIPPEDLERIFEPFFRTDPSRRGG-GTGLGLAIVKRIVELHGGTIEV 311
|
330
....*....|....*.
gi 685931000 486 ESGNGQ-TVFRVRLPM 500
Cdd:COG0642 312 ESEPGKgTTFTVTLPL 327
|
|
| phoR_proteo |
TIGR02966 |
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory ... |
229-498 |
3.42e-37 |
|
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems]
Pssm-ID: 274368 [Multi-domain] Cd Length: 333 Bit Score: 139.65 E-value: 3.42e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 229 TDDDHQISVRVRPGDtdpDNEVGIVGHTLNRLldnvdgalaHRVDsdlRMRQ-FITDASHELRTPLAAIQGYAELTRQDS 307
Cdd:TIGR02966 79 INSERVLEIRIAPYG---EEQKLLVARDVTRL---------RRLE---QMRRdFVANVSHELRTPLTVLRGYLETLADGP 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 308 SDLPPTTEYALARIESEARRMTLLVdellllsrlsegEDL------ETEDLDLTD---------LVINAVNDAAVAAPTH 372
Cdd:TIGR02966 144 DEDPEEWNRALEIMLEQSQRMQSLV------------EDLltlsrlESAASPLEDepvdmpallDHLRDEAEALSQGKNH 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 373 RWVKNLpDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIgitCHRTGPNApcVELSVTDDGPDIDPEILPHLFDRF 452
Cdd:TIGR02966 212 QITFEI-DGGVDVLGDEDELRSAFSNLVSNAIKYTPEGGTITV---RWRRDGGG--AEFSVTDTGIGIAPEHLPRLTERF 285
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 685931000 453 VRASKSRSNGS-GHGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRL 498
Cdd:TIGR02966 286 YRVDKSRSRDTgGTGLGLAIVKHVLSRHHARLEIESELGKgSTFSFIF 333
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
278-499 |
1.89e-34 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 135.68 E-value: 1.89e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 278 MRQFITDASHELRTPLAAIQGYAE-LTRQDSSDLPPTTEYALARIESEARRMTLLVdellllsrlsegEDL--------- 347
Cdd:COG4251 282 LEQFAYVASHDLREPLRKISGFSQlLEEDYGDKLDEEGREYLERIRDAAERMQALI------------DDLlaysrvgrq 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 348 --ETEDLDLTDL---VINAVNDAAVAAPTHRWVKNLPdepvWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRT 422
Cdd:COG4251 350 elEFEPVDLNELleeVLEDLEPRIEERGAEIEVGPLP----TVRGDPTLLRQVFQNLISNAIKYSRPGEPPRIEIGAERE 425
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 685931000 423 GPNapcVELSVTDDGPDIDPEILPHLFDRFVRASkSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLP 499
Cdd:COG4251 426 GGE---WVFSVRDNGIGIDPEYAEKIFEIFQRLH-SRDEYEGTGIGLAIVKKIVERHGGRIWVESEPGEgATFYFTLP 499
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
166-499 |
7.94e-34 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 133.28 E-value: 7.94e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 166 RLFVGVSLSLANQIIARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATmpltdddHQISVRVRPGDTD 245
Cdd:TIGR01386 145 QITVALDINAHTHLLDALRKWLILIAVLLVLLTALLGWWITRLGLEPLRRLSAVAARISP-------ESLDQRLDPSRAP 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 246 PdnEVGIVGHTLNRLLDNVDGALAhrvdsdlRMRQFITDASHELRTPLAAIQGYAE--LTRQDSSDlppttEY--ALARI 321
Cdd:TIGR01386 218 A--ELRELAQSFNAMLGRLEDAFQ-------RLSQFSADLAHELRTPLTNLLGQTQvaLSQPRTGE-----EYreVLESN 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 322 ESEARRMTLLVDELLLLSRLSEGE-DLETEDLDL-----------------TDLVINAVNDAAvaapthrwvknlpdepv 383
Cdd:TIGR01386 284 LEELERLSRMVSDMLFLARADNGQlALERVRLDLaaelakvaeyfeplaeeRGVRIRVEGEGL----------------- 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 384 wVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGItchrtGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSN-G 462
Cdd:TIGR01386 347 -VRGDPQMFRRAISNLLSNALRHTPDGGTITVRI-----ERRSDEVRVSVSNPGPGIPPEHLSRLFDRFYRVDPARSNsG 420
|
330 340 350
....*....|....*....|....*....|....*..
gi 685931000 463 SGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLP 499
Cdd:TIGR01386 421 EGTGLGLAIVRSIMEAHGGRASAESPDGKTRFILRFP 457
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
287-500 |
3.22e-33 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 129.53 E-value: 3.22e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 287 HELRTPLAAIQGYAELTRQDSSDLPPTTE--YALARIESEARRMtllvdellllsrlseGE------------DLETEDL 352
Cdd:COG4191 151 HEINNPLAAILGNAELLRRRLEDEPDPEElrEALERILEGAERA---------------AEivrslrafsrrdEEEREPV 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 353 DLTDLV--INAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNA--WVHTQPGVTVTIgitchRTGPNAPC 428
Cdd:COG4191 216 DLNELIdeALELLRPRLKARGIEVELDLPPDLPPVLGDPGQLEQVLLNLLINAidAMEEGEGGRITI-----STRREGDY 290
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 685931000 429 VELSVTDDGPDIDPEILPHLFDRFVrasKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPM 500
Cdd:COG4191 291 VVISVRDNGPGIPPEVLERIFEPFF---TTKPVGKGTGLGLSISYGIVEKHGGRIEVESEPGGgTTFTITLPL 360
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
387-500 |
4.95e-33 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 121.60 E-value: 4.95e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 387 GDHARLHQLVSNLLTNAWVHTQPGVTVTIgiTCHRTGPNapcVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHG 466
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITV--TLERDGDH---VEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRKIGGTG 75
|
90 100 110
....*....|....*....|....*....|....*
gi 685931000 467 LGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPM 500
Cdd:smart00387 76 LGLSIVKKLVELHGGEISVESEPGGgTTFTITLPL 110
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
287-504 |
4.01e-31 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 123.42 E-value: 4.01e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 287 HELRTPLAAIQGYAELTRQDSSDlPPTTEYaLARIESEARR-------MtllvdellllSRLSEGEDLETEDLDLTDLVI 359
Cdd:COG3852 144 HEIRNPLTGIRGAAQLLERELPD-DELREY-TQLIIEEADRlnnlvdrL----------LSFSRPRPPEREPVNLHEVLE 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 360 NAVNDAAVAAPTH-RWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHR-----TGPNAPCVELSV 433
Cdd:COG3852 212 RVLELLRAEAPKNiRIVRDYDPSLPEVLGDPDQLIQVLLNLVRNAAEAMPEGGTITIRTRVERqvtlgGLRPRLYVRIEV 291
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 685931000 434 TDDGPDIDPEILPHLFDRFVRaskSRSNGSGhgLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPMIEQQ 504
Cdd:COG3852 292 IDNGPGIPEEILDRIFEPFFT---TKEKGTG--LGLAIVQKIVEQHGGTIEVESEPGKgTTFRIYLPLEQAE 358
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
286-504 |
1.21e-29 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 120.45 E-value: 1.21e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 286 SHELRTPLAAIQGYAE-LTRQDSSDLPPTTEY---ALARIESEARRMtllvdellllsrlseGE------------DLET 349
Cdd:COG5000 209 AHEIKNPLTPIQLSAErLRRKLADKLEEDREDlerALDTIIRQVDRL---------------KRivdefldfarlpEPQL 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 350 EDLDLTDLV--INAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIgitchRTGPNAP 427
Cdd:COG5000 274 EPVDLNELLreVLALYEPALKEKDIRLELDLDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGGEIEV-----STRREDG 348
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 685931000 428 CVELSVTDDGPDIDPEILPHLFDRFVrasKSRSNGSGhgLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPMIEQQ 504
Cdd:COG5000 349 RVRIEVSDNGPGIPEEVLERIFEPFF---TTKPKGTG--LGLAIVKKIVEEHGGTIELESRPGGgTTFTIRLPLAEEA 421
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
387-500 |
4.63e-28 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 107.84 E-value: 4.63e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 387 GDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTgpnapcVELSVTDDGPDIDPEILPHLFDRFVRASKsrSNGSGHG 466
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLSEGGE------LTLTVEDNGIGIPPEDLPRIFEPFSTADK--RGGGGTG 72
|
90 100 110
....*....|....*....|....*....|....*
gi 685931000 467 LGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPM 500
Cdd:pfam02518 73 LGLSIVRKLVELLGGTITVESEPGGgTTVTLTLPL 107
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
194-484 |
4.42e-23 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 101.65 E-value: 4.42e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 194 ALVVTAALTVWVVGYALRPLRRVAataaevatmpltdddHQISVRvRPGDTDPDNEVGiVGHTLNRLLDNVDGALAHRVD 273
Cdd:PRK10337 170 ALPIMLIILMVLLGRELAPLKKLA---------------LALRMR-DPDSETPLNATG-VPSEVRPLVEALNQLFARTHA 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 274 SDLRMRQFITDASHELRTPLAAIQGYAELTrQDSSDLPPTTEYALARIES---EARRMTLLVDELLLLSRLSEGEDLETE 350
Cdd:PRK10337 233 MMVRERRFTSDAAHELRSPLAALKVQTEVA-QLSDDDPQARKKALLQLHAgidRATRLVDQLLTLSRLDSLDNLQDVAEI 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 351 DLD--LTDLVINAVNDAAVAAPTHRWvkNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRtgpnapc 428
Cdd:PRK10337 312 PLEdlLQSAVMDIYHTAQQAGIDVRL--TLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNARN------- 382
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 685931000 429 veLSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSghGLGLAIVSSIVKAHRGSVT 484
Cdd:PRK10337 383 --FTVRDNGPGVTPEALARIGERFYRPPGQEATGS--GLGLSIVRRIAKLHGMNVS 434
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
279-499 |
2.78e-22 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 99.31 E-value: 2.78e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 279 RQFITDASHELRTPLAAIQGYAELTrQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETED-LDLTD- 356
Cdd:PRK11006 205 RNFFANVSHELRTPLTVLQGYLEMM-QDQPLEGALREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTIDLNEkVDVPMm 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 357 LVINAVNDAAVAAPTHRWVKNLpDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIgitCHRTGPNAPCveLSVTDD 436
Cdd:PRK11006 284 LRVLEREAQTLSQGKHTITFEV-DNSLKVFGNEDQLRSAISNLVYNAVNHTPEGTHITV---RWQRVPQGAE--FSVEDN 357
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 685931000 437 GPDIDPEILPHLFDRFVRASKSRSNGS-GHGLGLAIVSSIVKAH--RGSVTAESGNGqTVFRVRLP 499
Cdd:PRK11006 358 GPGIAPEHIPRLTERFYRVDKARSRQTgGSGLGLAIVKHALSHHdsRLEIESEVGKG-TRFSFVLP 422
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
137-486 |
1.15e-21 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 97.59 E-value: 1.15e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 137 QVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQI-IARKKVTTVALVGAALVVTAALTVWVVGYALR-PLR 214
Cdd:NF012163 114 RFVVGPPDPVSDDGTRRPILVNGQEVGALGASPVERLTRNTDInFDSQQKRASWLIVALALLLAALAAFLLARGLLaPVK 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 215 RVAATAAEvatmpLTDDDHQISVRVRPGDtdpdnEVGIVGHTLNRLldnvdgalAHRVDSDLRMR-QFITDASHELRTPL 293
Cdd:NF012163 194 RLVEATHR-----LAAGDYTTRVTPTSND-----ELGKLAQDFNQL--------ASTLEKNEQMRrDFMADISHELRTPL 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 294 AAIQGYAELTrQDSsdLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGE-DLETEDLDLTDLvINAVNDAAVAAPTH 372
Cdd:NF012163 256 AVLRAELEAI-QDG--IRKFTPESLDSLQAEVGTLTKLVDDLHDLSMSDEGAlAYQKASVDLVPL-LEVEGGAFRERFAS 331
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 373 RWVK---NLPDEPVWVnGDHARLHQLVSNLLTNAWVHTQPGVTVTIgitchRTGPNAPCVELSVTDDGPDIDPEILPHLF 449
Cdd:NF012163 332 AGLElevSLPDSSLVF-GDRDRLMQLFNNLLENSLRYTDSGGSLHI-----SASQRPKEVTLTVADSAPGVSDEQLARLF 405
|
330 340 350
....*....|....*....|....*....|....*...
gi 685931000 450 DRFVRASKSRSNGS-GHGLGLAIVSSIVKAHRGSVTAE 486
Cdd:NF012163 406 ERFYRVEVSRNRASgGSGLGLAISLNIVQAHGGTLHAA 443
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
382-499 |
1.88e-21 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 97.15 E-value: 1.88e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 382 PVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIgitchRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRS- 460
Cdd:PRK09835 366 PCQVAGDPLMLRRAISNLLSNALRYTPAGEAITV-----RCQEVDHQVQLVVENPGTPIAPEHLPRLFDRFYRVDPSRQr 440
|
90 100 110
....*....|....*....|....*....|....*....
gi 685931000 461 NGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLP 499
Cdd:PRK09835 441 KGEGSGIGLAIVKSIVVAHKGTVAVTSDARGTRFVISLP 479
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
245-499 |
4.67e-21 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 95.44 E-value: 4.67e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 245 DPDNEVGIVGHTLNRLLDNVDGALAHRvdsdlrmRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESE 324
Cdd:PRK10604 186 DEGSSLERLGVAFNQMADNINALIASK-------KQLIDGIAHELRTPLVRLRYRLEMSDNLSAAESQALNRDIGQLEAL 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 325 ARRMTLLVDELLLLSrlsegeDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAW 404
Cdd:PRK10604 259 IEELLTYARLDRPQN------ELHLSEPDLPAWLSTHLADIQAVTPEKTVRLDTPHQGDYGALDMRLMERVLDNLLNNAL 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 405 VHTQPgvTVTIGITchRTGPNApCveLSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSG-HGLGLAIVSSIVKAHRGSV 483
Cdd:PRK10604 333 RYAHS--RVRVSLL--LDGNQA-C--LIVEDDGPGIPPEERERVFEPFVRLDPSRDRATGgCGLGLAIVHSIALAMGGSV 405
|
250
....*....|....*..
gi 685931000 484 TAESGN-GQTVFRVRLP 499
Cdd:PRK10604 406 NCDESElGGARFSFSWP 422
|
|
| MtrAB_MtrB |
NF040691 |
MtrAB system histidine kinase MtrB; |
156-499 |
9.66e-21 |
|
MtrAB system histidine kinase MtrB;
Pssm-ID: 468655 [Multi-domain] Cd Length: 507 Bit Score: 95.09 E-value: 9.66e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 156 QVDSSAAGADRLFVGVSLSLANQIIARKKvTTVALVGAALVVTAALTVWVVG-YALRPLRRVAataaevatmpltdddhQ 234
Cdd:NF040691 159 PVTLPVAGNYELYLLFPLEDEQSTLALVR-GTLLLGGLALVVLLGLIAWLVTrQVVAPVRSAA----------------R 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 235 ISVRVRPGDTDP------DNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSS 308
Cdd:NF040691 222 TAERFAAGDLSErmpvkgEDDLARLARSFNQMADSLQRQIRQLEELSRLQQRFVSDVSHELRTPLTTIRMAADVIHDSRD 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 309 DLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGE-DLETEDLDLTDLV--INAVNDAAVAAPTHRWVKNLPDEPVWV 385
Cdd:NF040691 302 DFDPATARSAELLHTELDRFESLLSDLLEISRFDAGAaELDVEPVDLRPLVrrVVDALRQLAERAGVELRVDAPGTPVVA 381
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 386 NGDHARLHQLVSNLLTNAWVHTQPG-VTVTIgitchrtGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGS- 463
Cdd:NF040691 382 EVDPRRVERVLRNLVVNAIEHGEGKpVVVTV-------AQDDTAVAVTVRDHGVGLKPGEVALVFDRFWRADPARARTTg 454
|
330 340 350
....*....|....*....|....*....|....*..
gi 685931000 464 GHGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLP 499
Cdd:NF040691 455 GTGLGLAIALEDARLHGGWLEAWGRPGQgSQFRLTLP 491
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-486 |
4.09e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 85.59 E-value: 4.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 388 DHARLHQLVSNLLTNAWVHTQPGVTVTIgitchRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGS-GHG 466
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRI-----RAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRASgGSG 75
|
90 100
....*....|....*....|
gi 685931000 467 LGLAIVSSIVKAHRGSVTAE 486
Cdd:cd16946 76 LGLAICHNIALAHGGTISAE 95
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
199-503 |
5.63e-20 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 92.39 E-value: 5.63e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 199 AALTVWVVGYA-LRPLRRvaataaevatmpLTDDDHQI-----SVRVRPGDTDpdnEVGIVGHTLNRLldnvdgalAHRV 272
Cdd:PRK10549 177 AALATFLLARGlLAPVKR------------LVEGTHKLaagdfTTRVTPTSRD---ELGRLAQDFNQL--------ASTL 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 273 DSDLRMRQ-FITDASHELRTPLAAIQGyaEL------TRQdssdlpPTTEyALARIESEARRMTLLVdellllsrlsegE 345
Cdd:PRK10549 234 EKNEQMRRdFMADISHELRTPLAVLRG--ELeaiqdgVRK------FTPE-SVASLQAEVGTLTKLV------------D 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 346 DLetEDLDLTD----------LVINAVNDAAVAAPTHRWVK-------NLPDEPVwVNGDHARLHQLVSNLLTNAWVHTQ 408
Cdd:PRK10549 293 DL--HQLSLSDegalayrktpVDLVPLLEVAGGAFRERFASrgltlqlSLPDSAT-VFGDPDRLMQLFNNLLENSLRYTD 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 409 PGVTVTigITCHRTGPNapcVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGS-GHGLGLAIVSSIVKAHRGSVTAE- 486
Cdd:PRK10549 370 SGGSLH--ISAEQRDKT---LRLTFADSAPGVSDEQLQKLFERFYRTEGSRNRASgGSGLGLAICLNIVEAHNGRIIAAh 444
|
330
....*....|....*..
gi 685931000 487 SGNGQTVFRVRLPMIEQ 503
Cdd:PRK10549 445 SPFGGVSITVELPLERD 461
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
181-499 |
1.07e-19 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 91.83 E-value: 1.07e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 181 ARKKVTTVA--LVGAALVVTAALTVWVVgyalRPLRRvaataaevatmpLTDddhqISVRVRPGDTDPDNEVGivGHTLN 258
Cdd:PRK11100 180 SERRILWAGalLLGIALLIGAGVVWWLN----RSIRR------------LTR----YADAVTEGKPVPLPKLG--SSELR 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 259 RLLDNVDgalahrvdsdlRMR------QFITD----ASHELRTPLAAIQGYAELTRQDssdLPPTT-EYALARIESEARR 327
Cdd:PRK11100 238 ELAQALE-----------SMRvklegkAYVEQyvqtLTHELKSPLAAIRGAAELLQED---PPPEDrARFTGNILTQSAR 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 328 MTLLVDELLLLSRLSEGEDLET-EDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVH 406
Cdd:PRK11100 304 LQQLIDRLLELARLEQRQELEVlEPVALAALLEELVEAREAQAAAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDF 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 407 TQPGVTVTIGITCHRTGpnapcVELSVTDDGPDIdPEI-LPHLFDRFVraSKSRSNG--SGHGLGLAIVSSIVKAHRGSV 483
Cdd:PRK11100 384 SPEGGTITLSAEVDGEQ-----VALSVEDQGPGI-PDYaLPRIFERFY--SLPRPANgrKSTGLGLAFVREVARLHGGEV 455
|
330
....*....|....*..
gi 685931000 484 TAESG-NGQTVFRVRLP 499
Cdd:PRK11100 456 TLRNRpEGGVLATLTLP 472
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
177-499 |
1.54e-19 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 90.03 E-value: 1.54e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 177 NQIIARKKVTTVALVGAALVVTAaltvWVVGYALRPLRRvaataaevatmpLTDDDHQISV-RVRPGDTDPD-NEVGIVG 254
Cdd:PRK10755 57 REAVASLLVPSLVMVSLTLLICF----QAVRWITRPLAE------------LQKELEARTAdNLTPIAIHSStLEIEAVT 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 255 HTLNRLLDNVDGALAhrvdsdlRMRQFITDASHELRTPLAAIQGYAEL-TRQDSSDLPPTteyaLARIEsearRMTllVD 333
Cdd:PRK10755 121 SALNQLVSRLTSTLD-------QERLFTADVAHELRTPLAGIRLHLELlEKQHHIDVAPL----IARLD----QMM--HT 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 334 ELLLLSRLSEGEDLET---EDLDLTDLVINAVNDAAVAAPTHR-----WVknLPDEPVWVNGDHARLHQLVSNLLTNAWV 405
Cdd:PRK10755 184 VEQLLQLARAGQSFSSghyQTVKLLEDVILPSQDELSEMLEQRqqtllLP--ESAADITVQGDATLLRLLLRNLVENAHR 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 406 HTQPGVTVTIGITCHRTGpnapcVELSVTDDGPDIDPEILPHLFDRFVRASkSRSNGSghGLGLAIVSSIVKAHRGSVTA 485
Cdd:PRK10755 262 YSPEGSTITIKLSQEDGG-----AVLAVEDEGPGIDESKCGELSKAFVRMD-SRYGGI--GLGLSIVSRITQLHHGQFFL 333
|
330
....*....|....*.
gi 685931000 486 ESGN--GQTVFRVRLP 499
Cdd:PRK10755 334 QNRQerSGTRAWVWLP 349
|
|
| HK_WalK |
NF033092 |
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in ... |
279-494 |
1.99e-18 |
|
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in Staphylococcus aureus (sp|Q2G2U4.1|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.
Pssm-ID: 467964 [Multi-domain] Cd Length: 594 Bit Score: 88.27 E-value: 1.99e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 279 RQFITDASHELRTPLAAIQGYAE-LTR---QDsSDLPPTTeyaLARIESEARRM----------------Tllvdellll 338
Cdd:NF033092 373 REFVANVSHELRTPLTTMRSYLEaLADgawKD-PELAPRF---LGVTQNETERMirlvndllqlsrmdskD--------- 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 339 srlsegEDLETEDLDLTDLV--INAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIG 416
Cdd:NF033092 440 ------YKLNKEWVNFNEFFnyIIDRFEMILKNKNITFKREFPKRDLWVEIDTDKITQVLDNIISNAIKYSPEGGTITFR 513
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 417 ITCHRTgpnapCVELSVTDDGPDIDPEILPHLFDRFVRASKSRS-NGSGHGLGLAIVSSIVKAHRGSVTAES--GNGQTV 493
Cdd:NF033092 514 LLETHN-----RIIISISDQGLGIPKKDLDKIFDRFYRVDKARSrKMGGTGLGLAIAKEVVEAHGGRIWAESeeGKGTTI 588
|
.
gi 685931000 494 F 494
Cdd:NF033092 589 Y 589
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
287-503 |
3.52e-18 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 87.72 E-value: 3.52e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 287 HELRTPLAAIQGYAELTrQDSSDLPPTTEYaLARIESEARRMtllvdellllsrlsegeDLETEDL-------------- 352
Cdd:PRK11360 399 HEIRNPLTAIRGYVQIW-RQQTSDPPSQEY-LSVVLREVDRL-----------------NKVIDQLlefsrpresqwqpv 459
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 353 DLTDLVinaVNDAAVAAPTHRWVK---------NLPdePVWVngDHARLHQLVSNLLTNAWVHTQPGVTVTIgiTCHRTG 423
Cdd:PRK11360 460 SLNALV---EEVLQLFQTAGVQARvdfeteldnELP--PIWA--DPELLKQVLLNILINAVQAISARGKIRI--RTWQYS 530
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 424 PNAPCVElsVTDDGPDIDPEILPHLFDRFVrASKSrsngSGHGLGLAIVSSIVKAHRGSVTAES--GNGqTVFRVRLPMI 501
Cdd:PRK11360 531 DGQVAVS--IEDNGCGIDPELLKKIFDPFF-TTKA----KGTGLGLALSQRIINAHGGDIEVESepGVG-TTFTLYLPIN 602
|
..
gi 685931000 502 EQ 503
Cdd:PRK11360 603 PQ 604
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
392-499 |
2.63e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 77.43 E-value: 2.63e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 392 LHQLVSNLLTNAWVHTQPGVTVTIGItchrtGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRsNGSGHGLGLAI 471
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPENTRIYITS-----FLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSR-NTEGAGLGLSI 74
|
90 100
....*....|....*....|....*...
gi 685931000 472 VSSIVKAHRGSVTAESGNGQTVFRVRLP 499
Cdd:cd16923 75 AKAIIELHGGSASAEYDDNHDLFKVRLP 102
|
|
| TMAO_torS |
TIGR02956 |
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the ... |
280-509 |
5.80e-17 |
|
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems]
Pssm-ID: 274362 [Multi-domain] Cd Length: 968 Bit Score: 84.44 E-value: 5.80e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 280 QFITDASHELRTPLAAIQGYAELTRQdsSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGE-DLETEDLDLTDLV 358
Cdd:TIGR02956 466 AFLATMSHEIRTPLNGILGTLELLGD--TGLTSQQQQYLQVINRSGESLLDILNDILDYSKIEAGHlSISPRPFDLNALL 543
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 359 --INAVNDAAVAAPTHRWVKNLPDE-PVWVNGDHARLHQLVSNLLTNAWVHTQPGvTVTIGITCHRTGPnapcVELSVTD 435
Cdd:TIGR02956 544 ddVHHLMVSRAQLKGIQLRLNIPEQlPNWWQGDGPRIRQVLINLVGNAIKFTDRG-SVVLRVSLNDDSS----LLFEVED 618
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 685931000 436 DGPDIDPEILPHLFDRFVRASKSRSNGsGHGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPMIEQQIATTA 509
Cdd:TIGR02956 619 TGCGIAEEEQATLFDAFTQADGRRRSG-GTGLGLAISQRLVEAMDGELGVESELGVgSCFWFTLPLTRGKPAEDS 692
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
392-500 |
5.96e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 76.38 E-value: 5.96e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 392 LHQLVSNLLTNAWVHTQPGvtvTIGITCHRTGPNAPCVEL--SVTDDGPDIDPEILPHLFDRFVRA--SKSRSNGsGHGL 467
Cdd:cd16922 1 LRQILLNLLGNAIKFTEEG---EVTLRVSLEEEEEDGVQLrfSVEDTGIGIPEEQQARLFEPFSQAdsSTTRKYG-GTGL 76
|
90 100 110
....*....|....*....|....*....|....
gi 685931000 468 GLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPM 500
Cdd:cd16922 77 GLAISKKLVELMGGDISVESEPGQgSTFTFTLPL 110
|
|
| marine_sort_HK |
TIGR03785 |
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is ... |
278-499 |
1.06e-16 |
|
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is paired with an adjacent response regulator (TIGR03787) gene. It co-occurs with a variant sortase enzyme (TIGR03784), usually in the same gene neighborhood, in proteobacterial species most of which are marine, and with an LPXTG motif-containing sortase target conserved protein (TIGR03788). Sortases and LPXTG proteins are far more common in Gram-positive bacteria, where sortase systems mediate attachment to the cell wall or cross-linking of pilin structures. We give this predicted sensor histidine kinase the gene symbol psdS, for Proteobacterial Dedicated Sortase system Sensor histidine kinase.
Pssm-ID: 163497 [Multi-domain] Cd Length: 703 Bit Score: 83.25 E-value: 1.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 278 MRQFITDASHELRTPLAAIQGYAE-LTRQDSSDLppTTEYA---------LARI---ESEARRMTLLVdellllsrlseg 344
Cdd:TIGR03785 485 LENMSSRLSHELRTPVAVVRSSLEnLELQALEQE--KQKYLeraregterLSMIlnnMSEATRLEQAI------------ 550
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 345 EDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGItcHRTGP 424
Cdd:TIGR03785 551 QSAEVEDFDLSEVLSGCMQGYQMTYPPQRFELNIPETPLVMRGSPELIAQMLDKLVDNAREFSPEDGLIEVGL--SQNKS 628
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 685931000 425 NApcvELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGH-GLGLAIVSSIVKAHRGSVTAE--SGNGQTVFRVRLP 499
Cdd:TIGR03785 629 HA---LLTVSNEGPPLPEDMGEQLFDSMVSVRDQGAQDQPHlGLGLYIVRLIADFHQGRIQAEnrQQNDGVVFRISLP 703
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
286-500 |
1.15e-16 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 83.16 E-value: 1.15e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 286 SHELRTPLAAIQGYAELTRQD-SSDLPPTTEYA-------------------LARIESEarrmtllvdellllsrlseGE 345
Cdd:PRK10490 672 SHDLRTPLTVLFGQAEILTLDlASEGSPHARQAseirqqvlnttrlvnnlldMARIQSG-------------------GF 732
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 346 DLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGpn 425
Cdd:PRK10490 733 NLRKEWLTLEEVVGSALQMLEPGLSGHPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAEIGIDAHVEGER-- 810
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 685931000 426 apcVELSVTDDGPDIDPEILPHLFDRFVRASKsRSNGSGHGLGLAIVSSIVKAHRGSVTAESG-NGQTVFRVRLPM 500
Cdd:PRK10490 811 ---LQLDVWDNGPGIPPGQEQLIFDKFARGNK-ESAIPGVGLGLAICRAIVEVHGGTIWAENRpEGGACFRVTLPL 882
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
392-499 |
1.24e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 75.18 E-value: 1.24e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 392 LHQLVSNLLTNAWVHTQPGVTVtigitchRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSnGSGHGLGLAI 471
Cdd:cd16950 1 LKRVLSNLVDNALRYGGGWVEV-------SSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNARG-TSGTGLGLAI 72
|
90 100
....*....|....*....|....*....
gi 685931000 472 VSSIVKAHRGSVT-AESGNGQTVFRVRLP 499
Cdd:cd16950 73 VQRISDAHGGSLTlANRAGGGLCARIELP 101
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
286-502 |
2.10e-16 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 81.50 E-value: 2.10e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 286 SHELRTPLAAIQGYAELtrqdssdLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDL-DLTDLVINAVND 364
Cdd:PRK09467 237 SHDLRTPLTRIRLATEM-------MSEEDGYLAESINKDIEECNAIIEQFIDYLRTGQEMPMEMADLnALLGEVIAAESG 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 365 AAVAAPTHrwvknLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRtgpnapcVELSVTDDGPDIDPEI 444
Cdd:PRK09467 310 YEREIETA-----LQPGPIEVPMNPIAIKRALANLVVNAARYGNGWIKVSSGTEGKR-------AWFQVEDDGPGIPPEQ 377
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 685931000 445 LPHLFDRFVRASKSRSnGSGHGLGLAIVSSIVKAHRGSVT-AESGNGQTVFRVRLPMIE 502
Cdd:PRK09467 378 LKHLFQPFTRGDSARG-SSGTGLGLAIVKRIVDQHNGKVElGNSEEGGLSARAWLPLTT 435
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
392-491 |
5.00e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 73.78 E-value: 5.00e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 392 LHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGpnapcVELSVTDDGPDIDPEILPHLFDRFVRASKSRS-NGSGHGLGLA 470
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQEESG-----ARLSVEDTGPGIPPEHIPRLTERFYRVDIERCrNTGGTGLGLA 75
|
90 100
....*....|....*....|.
gi 685931000 471 IVSSIVKAHRGSVTAESGNGQ 491
Cdd:cd16952 76 IVKHVMSRHDARLLIASELGK 96
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
392-500 |
7.42e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 73.13 E-value: 7.42e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 392 LHQLVSNLLTNAwVHTQPGvTVTIGITCHRTGpnapcVELSVTDDGPDIDPEILPHLFDRFVRASKSRS-NGSGHGLGLA 470
Cdd:cd16949 1 LARALENVLRNA-LRYSPS-KILLDISQDGDQ-----WTITITDDGPGVPEDQLEQIFLPFYRVDSARDrESGGTGLGLA 73
|
90 100 110
....*....|....*....|....*....|..
gi 685931000 471 IVSSIVKAHRGSVTAESG--NGQTVfRVRLPM 500
Cdd:cd16949 74 IAERAIEQHGGKIKASNRkpGGLRV-RIWLPA 104
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
392-499 |
7.92e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 73.13 E-value: 7.92e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 392 LHQLVSNLLTNAWVHTQPGVTVTIGITCHRTgPNAPcvELSVTDDGPDIDPEILPHLFDRFVRAsKSRSNGSGHGLGLAI 471
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRRPPRIEVGAEDV-GEEW--TFYVRDNGIGIDPEYAEKVFGIFQRL-HSREEYEGTGVGLAI 76
|
90 100
....*....|....*....|....*....
gi 685931000 472 VSSIVKAHRGSVTAESGNGQ-TVFRVRLP 499
Cdd:cd16921 77 VRKIIERHGGRIWLESEPGEgTTFYFTLP 105
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
392-499 |
9.42e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 73.20 E-value: 9.42e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 392 LHQLVSNLLTNAwVHTQPGVTVTI--------GITCHRTGPNAPCvELSVTDDGPDIDPEILPHLFDRFVrasKSRSNGS 463
Cdd:cd16918 1 LIQVFLNLVRNA-AQALAGSGGEIilrtrtqrQVTLGHPRHRLAL-RVSVIDNGPGIPPDLQDTIFYPMV---SGRENGT 75
|
90 100 110
....*....|....*....|....*....|....*.
gi 685931000 464 GhgLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLP 499
Cdd:cd16918 76 G--LGLAIAQNIVSQHGGVIECDSQPGHTVFSVSLP 109
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
238-486 |
1.28e-15 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 79.21 E-value: 1.28e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 238 RVRPGD--TDPDNEVGI-----VGHTLNRLLDnvdgALAHRVDSDLRMrqfITDASHELRTPLAAIQ-GYAELTRQ--DS 307
Cdd:PRK09470 203 EVAQGNlrQHPELETGPqefrqAGASFNQMVT----ALERMMTSQQRL---LSDISHELRTPLTRLQlATALLRRRqgES 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 308 SDLpptteyalARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLvinavndaavaapthrWV------------ 375
Cdd:PRK09470 276 KEL--------ERIETEAQRLDSMINDLLVLSRNQQKNHLERETFKANSL----------------WSevledakfeaeq 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 376 --KNL----PDEPVWVNGDHARLHQLVSNLLTNAWVHTQPgvTVTIGITCHRTGpnapcVELSVTDDGPDIDPEILPHLF 449
Cdd:PRK09470 332 mgKSLtvsaPPGPWPINGNPNALASALENIVRNALRYSHT--KIEVAFSVDKDG-----LTITVDDDGPGVPEEEREQIF 404
|
250 260 270
....*....|....*....|....*....|....*...
gi 685931000 450 DRFVRASKSRSNGSG-HGLGLAIVSSIVKAHRGSVTAE 486
Cdd:PRK09470 405 RPFYRVDEARDRESGgTGLGLAIVENAIQQHRGWVKAE 442
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
381-490 |
1.11e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 70.13 E-value: 1.11e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 381 EPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITchrtgpNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKsrS 460
Cdd:cd16940 3 ADIQVQGDALLLFLLLRNLVDNAVRYSPQGSRVEIKLS------ADDGAVIRVEDNGPGIDEEELEALFERFYRSDG--Q 74
|
90 100 110
....*....|....*....|....*....|
gi 685931000 461 NGSGHGLGLAIVSSIVKAHRGSVTAESGNG 490
Cdd:cd16940 75 NYGGSGLGLSIVKRIVELHGGQIFLGNAQG 104
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
286-499 |
3.17e-14 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 75.01 E-value: 3.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 286 SHELRTPLAAIQGYAELTrQDSSDlpptTEYA--LARIESEARRMtllvdellllsrlsegEDLETEDLDLT-------- 355
Cdd:COG5809 278 AHEIRNPLTSLKGFIQLL-KDTID----EEQKtyLDIMLSELDRI----------------ESIISEFLVLAkpqaikye 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 356 --DL------VINAVNDAAVAAPTHRWVKNLPDEPVwVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRtgPNAp 427
Cdd:COG5809 337 pkDLntlieeVIPLLQPQALLKNVQIELELEDDIPD-ILGDENQLKQVFINLLKNAIEAMPEGGNITIETKAED--DDK- 412
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 685931000 428 cVELSVTDDGPDIDPEILPHLFDRFVrASKSRsngsGHGLGLAIVSSIVKAHRGSVTAES--GNGqTVFRVRLP 499
Cdd:COG5809 413 -VVISVTDEGCGIPEERLKKLGEPFY-TTKEK----GTGLGLMVSYKIIEEHGGKITVESevGKG-TTFSITLP 479
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
390-499 |
3.37e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 68.60 E-value: 3.37e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 390 ARLHQLVSNLLTNAwVHTQPGV-TVTIgitchRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVrasKSRSNGSGHGLG 468
Cdd:cd16943 2 SQLNQVLLNLLVNA-AQAMEGRgRITI-----RTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFF---TTKPVGEGTGLG 72
|
90 100 110
....*....|....*....|....*....|..
gi 685931000 469 LAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLP 499
Cdd:cd16943 73 LSLSYRIIQKHGGTIRVASVPGGgTRFTIILP 104
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
392-500 |
3.65e-14 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 74.11 E-value: 3.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 392 LHQLVSNLLTNAWVHT--QPGVTVTIGITCHRTGPnapCVELSVTDDGPDIDPEILPHLFDRFVRaSKsrsNGSGHGLGL 469
Cdd:COG3290 282 LVTILGNLLDNAIEAVekLPEEERRVELSIRDDGD---ELVIEVEDSGPGIPEELLEKIFERGFS-TK---LGEGRGLGL 354
|
90 100 110
....*....|....*....|....*....|..
gi 685931000 470 AIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPM 500
Cdd:COG3290 355 ALVKQIVEKYGGTIEVESEEGEgTVFTVRLPK 386
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
392-499 |
1.36e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 66.65 E-value: 1.36e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 392 LHQLVSNLLTNAwVHTQPGVTVTIGITCHRTGPNAP-CVELSVTDDGPDIDPEILPHLFDRFVrASKSrsngSGHGLGLA 470
Cdd:cd16920 1 IQQVLINLVRNG-IEAMSEGGCERRELTIRTSPADDrAVTISVKDTGPGIAEEVAGQLFDPFY-TTKS----EGLGMGLS 74
|
90 100 110
....*....|....*....|....*....|
gi 685931000 471 IVSSIVKAHRGSVTAES-GNGQTVFRVRLP 499
Cdd:cd16920 75 ICRSIIEAHGGRLSVESpAGGGATFQFTLP 104
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
238-504 |
2.04e-13 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 72.79 E-value: 2.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 238 RVRPGDTDPDNEVGIVGHTLNRLLDNVD--------GALAHRVDSDLRMRQFITDAS---HELRTPLAAIQGYAELTRQD 306
Cdd:PRK13837 399 RQRYGLRPPAGELQLLELALDCLAHAIErrrleterDALERRLEHARRLEAVGTLASgiaHNFNNILGAILGYAEMALNK 478
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 307 SSDLPPTTEYALARIESEARRMTLLVDELLLLSRLsegeDLETEDLDLTDLVINAVNDAAVAAPTH-RWVKNLPDEPVWV 385
Cdd:PRK13837 479 LARHSRAARYIDEIISAGARARLIIDQILAFGRKG----ERNTKPFDLSELVTEIAPLLRVSLPPGvELDFDQDQEPAVV 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 386 NGDHARLHQLVSNLLTNAWVHTQPGVTVTI----------GITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVra 455
Cdd:PRK13837 555 EGNPAELQQVLMNLCSNAAQAMDGAGRVDIslsraklrapKVLSHGVLPPGRYVLLRVSDTGAGIDEAVLPHIFEPFF-- 632
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 685931000 456 sKSRSNGSghGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPMIEQQ 504
Cdd:PRK13837 633 -TTRAGGT--GLGLATVHGIVSAHAGYIDVQSTVGRgTRFDVYLPPSSKV 679
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
388-499 |
3.02e-13 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 65.98 E-value: 3.02e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 388 DHARLHQLVSNLLTNAWVHTQPGVTvtigITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRF--VRASKSRSNGsGH 465
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGR----IRCILEKFRLNRFLLTVSDSGPGIPPNLREEIFERFrqGDGSSTRAHG-GT 75
|
90 100 110
....*....|....*....|....*....|....*
gi 685931000 466 GLGLAIVSSIVKAHRGSVT-AESGNGQTVFRVRLP 499
Cdd:cd16925 76 GLGLSIVKEFVELHGGTVTvSDAPGGGALFQVELP 110
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
392-499 |
6.53e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 64.76 E-value: 6.53e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 392 LHQLVSNLLTNAWVHTQPgvTVTIGITChrtgpNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGS-GHGLGLA 470
Cdd:cd16939 1 MARALDNLLRNALRYAHR--TVRIALLV-----SGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATgGFGLGLA 73
|
90 100 110
....*....|....*....|....*....|
gi 685931000 471 IVSSIVKAHRGSVTA-ESGNGQTVFRVRLP 499
Cdd:cd16939 74 IVHRVALWHGGHVECdDSELGGACFRLTWP 103
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
281-500 |
7.95e-13 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 71.09 E-value: 7.95e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 281 FITDASHELRTPLAAIQGYAELTrQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETED-----LDLT 355
Cdd:PRK11466 447 FLAAMSHEIRTPLYGILGTAQLL-ADNPALNAQRDDLRAITDSGESLLTILNDILDYSAIEAGGKNVSVSDepfepRPLL 525
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 356 DLVINAVNDAAVAAPThRWVKNLPDE-PVWVNGDHARLHQLVSNLLTNAWVHTQPGVtvtigiTCHRTGPNAPCVELSVT 434
Cdd:PRK11466 526 ESTLQLMSGRVKGRPI-RLATDIADDlPTALMGDPRRIRQVITNLLSNALRFTDEGS------IVLRSRTDGEQWLVEVE 598
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 685931000 435 DDGPDIDPEILPHLFDRFVRASKSRsngSGHGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPM 500
Cdd:PRK11466 599 DSGCGIDPAKLAEIFQPFVQVSGKR---GGTGLGLTISSRLAQAMGGELSATSTPEVgSCFCLRLPL 662
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
286-504 |
1.47e-12 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 69.43 E-value: 1.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 286 SHELRTPLAAIQGYAELTRQDSsdlPPTTE-YALARI-ESEARRMTLLVDELLLLSRLSegeDLETEDLDLTDLV----- 358
Cdd:PRK10364 245 AHEIRNPLSSIKGLAKYFAERA---PAGGEaHQLAQVmAKEADRLNRVVSELLELVKPT---HLALQAVDLNDLInhslq 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 359 -INAVNDAAVAAPTHRWVKNLPDEPVwvngDHARLHQLVSNLLTNAwVHTQP-GVTVTIGITCHRTGpnapcVELSVTDD 436
Cdd:PRK10364 319 lVSQDANSREIQLRFTANDTLPEIQA----DPDRLTQVLLNLYLNA-IQAIGqHGVISVTASESGAG-----VKISVTDS 388
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 685931000 437 GPDIDPEILPHLFDRFVRasksrSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPMIEQQ 504
Cdd:PRK10364 389 GKGIAADQLEAIFTPYFT-----TKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKgATFTLWLPVNITR 452
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
277-329 |
2.15e-12 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 62.23 E-value: 2.15e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 685931000 277 RMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYaLARIESEARRMT 329
Cdd:cd00082 3 AKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREY-LERIREEAERLL 54
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
277-328 |
3.35e-12 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 61.46 E-value: 3.35e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 685931000 277 RMRQFITDASHELRTPLAAIQGYAELTRqdSSDLPPTTEYALARIESEARRM 328
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLR--DEKLDEEQREYLETILRSAERL 50
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
277-328 |
4.59e-12 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 61.04 E-value: 4.59e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 685931000 277 RMRQFITDASHELRTPLAAIQGYAELTRQDssDLPPTTEYALARIESEARRM 328
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDT--ELSEEQREYLETILREAERL 50
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
375-499 |
7.12e-12 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 67.45 E-value: 7.12e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 375 VKNLPDEPVWVNGDHARLHQLVSNLLTNAwVHTQP-GVTVTIGITchrtgPNAPCVELSVTDDGPDIDPEILPHLFDRFV 453
Cdd:COG5805 379 RLELLDEDPFIYCDENQIKQVFINLIKNA-IEAMPnGGTITIHTE-----EEDNSVIIRVIDEGIGIPEERLKKLGEPFF 452
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 685931000 454 RASKSrsngsGHGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLP 499
Cdd:COG5805 453 TTKEK-----GTGLGLMVSYKIIENHNGTIDIDSKVGKgTTFTITLP 494
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
377-498 |
7.15e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 62.65 E-value: 7.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 377 NLPDEPVWVnGDHARLHQLVSNLLTNA--WVHTQpgVTVTIgitchRTGPNApcVELSVTDDGPDIDPEILPHLFDRFVR 454
Cdd:cd16954 24 DISPELRFP-GERNDLMELLGNLLDNAckWCLEF--VEVTA-----RQTDGG--LHLIVDDDGPGVPESQRSKIFQRGQR 93
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 685931000 455 ASKSRSngsGHGLGLAIVSSIVKAHRGSVTAE-SGNGQTVFRVRL 498
Cdd:cd16954 94 LDEQRP---GQGLGLAIAKEIVEQYGGELSLSdSPLGGARFEVVF 135
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
392-499 |
1.14e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 61.43 E-value: 1.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 392 LHQLVSNLLTNAwVHTQPGVTVTIGItchRTGPNAPCVELSVTDDGPDIDPEILPHLFDRF-VRASKSRSNGSGHGLGLA 470
Cdd:cd16953 1 LGQVLRNLIGNA-ISFSPPDTGRITV---SAMPTGKMVTISVEDEGPGIPQEKLESIFDRFyTERPANEAFGQHSGLGLS 76
|
90 100 110
....*....|....*....|....*....|....
gi 685931000 471 IVSSIVKAHRGSVTAE--SGNGQTV---FRVRLP 499
Cdd:cd16953 77 ISRQIIEAHGGISVAEnhNQPGQVIgarFTVQLP 110
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
377-498 |
6.47e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 59.83 E-value: 6.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 377 NLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGvtVTIGITCHRTGPNapcVELSVTDDGPDIDPEILPHLFDRFVRAS 456
Cdd:cd16947 6 NIPDRPIYANANTEALQRILKNLISNAIKYGSDG--KFLGMTLREDEKH---VYIDIWDKGKGISETEKDHVFERLYTLE 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 685931000 457 KSRSNG-SGHGLGLAIVSSIVKAHRGSVTAESG-NGQTVFRVRL 498
Cdd:cd16947 81 DSRNSAkQGNGLGLTITKRLAESMGGSIYVNSKpYEKTVFTVTL 124
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
379-509 |
8.55e-11 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 64.61 E-value: 8.55e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 379 PDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGvTVTIGITCHRTgpnapCVELSVTDDGPDIDPEILPHLFDRFVRASKS 458
Cdd:PRK10841 550 PDVPVALNGDPMRLQQVISNLLSNAIKFTDTG-CIVLHVRVDGD-----YLSFRVRDTGVGIPAKEVVRLFDPFFQVGTG 623
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 685931000 459 -RSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPMIEQQIATTA 509
Cdd:PRK10841 624 vQRNFQGTGLGLAICEKLINMMDGDISVDSEPGMgSQFTIRIPLYGAQYPQKK 676
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
396-499 |
8.83e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 58.84 E-value: 8.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 396 VSNLLTNAWVHT----QPGVTVTIGITCHrtgpnAPCVELSVTDDGPDIDPEILPHLFDRFVraskSRSNGSGHGLGLAI 471
Cdd:cd16915 5 VGNLIDNALDALaatgAPNKQVEVFLRDE-----GDDLVIEVRDTGPGIAPELRDKVFERGV----STKGQGERGIGLAL 75
|
90 100
....*....|....*....|....*....
gi 685931000 472 VSSIVKAHRGSVTAESG-NGQTVFRVRLP 499
Cdd:cd16915 76 VRQSVERLGGSITVESEpGGGTTFSIRIP 104
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
272-506 |
1.73e-10 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 63.60 E-value: 1.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 272 VDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEyALARIESEARRMTLLVDELLLLSRLSEGE-DLETE 350
Cdd:PRK09959 706 INATVAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVE-AISLAYATGQSLLGLIGEILDVDKIESGNyQLQPQ 784
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 351 DLDLTDLVINAVNDAAVAAPTHRWV----KNLPDEPVwVNGDHARLHQLVSNLLTNAWVHTQPGvTVTIGITCHRTGPNA 426
Cdd:PRK09959 785 WVDIPTLVQNTCHSFGAIAASKSIAlscsSTFPDHYL-VKIDPQAFKQVLSNLLSNALKFTTEG-AVKITTSLGHIDDNH 862
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 427 PCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNgSGHGLGLAIVSSIVKAHRGSVTAESGNG-QTVFRVRLPM-IEQQ 504
Cdd:PRK09959 863 AVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQ-TGSGLGLMICKELIKNMQGDLSLESHPGiGTTFTITIPVeISQQ 941
|
..
gi 685931000 505 IA 506
Cdd:PRK09959 942 VA 943
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
385-491 |
5.51e-10 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 61.12 E-value: 5.51e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 385 VNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITcHRTGPNapcVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNgSG 464
Cdd:PRK09303 266 VYADQERIRQVLLNLLDNAIKYTPEGGTITLSML-HRTTQK---VQVSICDTGPGIPEEEQERIFEDRVRLPRDEGT-EG 340
|
90 100
....*....|....*....|....*..
gi 685931000 465 HGLGLAIVSSIVKAHRGSVTAESGNGQ 491
Cdd:PRK09303 341 YGIGLSVCRRIVRVHYGQIWVDSEPGQ 367
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-484 |
2.45e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 54.77 E-value: 2.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 388 DHARLHQLVSNLLTNAWVHTQPGVTVTIgitchRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGL 467
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIAL-----QLEADTEGIELLVFDEGSGIPDYALNRVFERFYSLPRPHSGQKSTGL 75
|
90
....*....|....*..
gi 685931000 468 GLAIVSSIVKAHRGSVT 484
Cdd:cd16945 76 GLAFVQEVAQLHGGRIT 92
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-486 |
8.39e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 53.23 E-value: 8.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 388 DHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTgpnapCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGL 467
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEE-----YLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSGGHYGM 75
|
90
....*....|....*....
gi 685931000 468 GLAIVSSIVKAHRGSVTAE 486
Cdd:cd16975 76 GLYIAKNLVEKHGGSLIIE 94
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
392-498 |
2.11e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 52.07 E-value: 2.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 392 LHQLVSNLLTNAW--VHTQPgvTVTIGITCHRTGPNapcVELSVTDDGPDIDPEILPHLFDRFVrasKSRSNGSGHGLGL 469
Cdd:cd16976 1 IQQVLMNLLQNALdaMGKVE--NPRIRIAARRLGGR---LVLVVRDNGPGIAEEHLSRVFDPFF---TTKPVGKGTGLGL 72
|
90 100 110
....*....|....*....|....*....|
gi 685931000 470 AIVSSIVKAHRGS-VTAESGNGQTVFRVRL 498
Cdd:cd16976 73 SISYGIVEEHGGRlSVANEEGAGARFTFDL 102
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
188-502 |
2.22e-08 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 56.96 E-value: 2.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 188 VALVgaALVVTAALTVWVVGYAL-RPLRRVAATAAEVATMPLtdddhqiSVRVrpgdtdPDN---EVGIVGHTLNRLLDN 263
Cdd:PRK15347 301 FALL--ILVLLTSVLFLLLRRYLaKPLWRFVDIINKTGPAAL-------EPRL------PENrldELGSIAKAYNQLLDT 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 264 VDG----------------ALAHRVDSDLRMRQ--FITDASHELRTPLAAIQGYAELTRQDSS-----DLPPT----TEY 316
Cdd:PRK15347 366 LNEqydtlenkvaertqalAEAKQRAEQANKRKseHLTTISHEIRTPLNGVLGALELLQNTPLtaeqmDLADTarqcTLS 445
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 317 ALA---------RIESEarRMTLLVDellllsrlsegedlETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNG 387
Cdd:PRK15347 446 LLAiinnlldfsRIESG--QMTLSLE--------------ETALLPLLDQAMLTIQGPAQSKSLTLRTFVGAHVPLYLHL 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 388 DHARLHQLVSNLLTNAWVHTQPGvtvTIGITCHRTGpNAPCveLSVTDDGPDIDPEILPHLFDRFVRASksrSNGSGHGL 467
Cdd:PRK15347 510 DSLRLRQILVNLLGNAVKFTETG---GIRLRVKRHE-QQLC--FTVEDTGCGIDIQQQQQIFTPFYQAD---THSQGTGL 580
|
330 340 350
....*....|....*....|....*....|....*.
gi 685931000 468 GLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLPMIE 502
Cdd:PRK15347 581 GLTIASSLAKMMGGELTLFSTPGVgSCFSLVLPLNE 616
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
378-499 |
9.11e-08 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 54.53 E-value: 9.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 378 LPDepvwvNGDHARLHQLVS---NLLTNAW--VHTQPGVTVTIGITcHRTGpnapCVELSVTDDGPDIDPEILPHLFDRF 452
Cdd:PRK11086 422 LPD-----SGDEDQVHELITilgNLIENALeaVGGEEGGEISVSLH-YRNG----WLHCEVSDDGPGIAPDEIDAIFDKG 491
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 685931000 453 VrASKsrsnGSGHGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLP 499
Cdd:PRK11086 492 Y-STK----GSNRGVGLYLVKQSVENLGGSIAVESEPGVgTQFFVQIP 534
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
429-506 |
5.98e-07 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 51.98 E-value: 5.98e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 429 VELSVTDDGPDIDPEILPHLFDRFVrasKSRSNGSGHGLGLAIVSSIVKAHRGSVTAES--GNGQTVfRVRLPMIEQQIA 506
Cdd:PRK13557 325 VSIAVTDTGSGMPPEILARVMDPFF---TTKEEGKGTGLGLSMVYGFAKQSGGAVRIYSevGEGTTV-RLYFPASDQAEN 400
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
280-487 |
1.08e-06 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 51.23 E-value: 1.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 280 QFITDASHELRTPLAAIQGY---AELTRQDSSDLPPTTeyALARIESEARRMTLLVDELLLLSRLSegeDLETEDLDLTD 356
Cdd:COG4192 435 QTMTSLAHELNQPLNAMSMYlfsAKKALEQENYAQLPT--SLDKIEGLIERMDKIIKSLRQFSRKS---DTPLQPVDLRQ 509
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 357 LVINAVNDAAVAAPTHRWVKNLPDEPvWVNGDHARLHQLVSNLLTNAW--VHTQPGVTVTIGItchrtgpNAPCVELSVT 434
Cdd:COG4192 510 VIEQAWELVESRAKPQQITLHIPDDL-MVQGDQVLLEQVLVNLLVNALdaVATQPQISVDLLS-------NAENLRVAIS 581
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 685931000 435 DDGPDIDpeILPHLFDRFVrASKSrsngSGHGLGLAIVSSIVKAHRGSVTAES 487
Cdd:COG4192 582 DNGNGWP--LVDKLFTPFT-TTKE----VGLGLGLSICRSIMQQFGGDLYLAS 627
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
414-503 |
1.63e-06 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 50.40 E-value: 1.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 414 TIGITCHRTGPNapcVELSVTDDGPDIDPEILPHLFDRFvrasksRSNGSGHGLGLAIVSSIVKAHRG---SVTAESGNG 490
Cdd:COG2972 361 TIRISIRKEGDR---LVITVEDNGVGMPEEKLEKLLEEL------SSKGEGRGIGLRNVRERLKLYYGeeyGLEIESEPG 431
|
90
....*....|....
gi 685931000 491 Q-TVFRVRLPMIEQ 503
Cdd:COG2972 432 EgTTVTIRIPLEEE 445
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
429-499 |
2.77e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 46.22 E-value: 2.77e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 685931000 429 VELSVTDDGPDIDPEILPHLFDRFVrasKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQ-TVFRVRLP 499
Cdd:cd16919 48 VCLEVSDTGSGMPAEVLRRAFEPFF---TTKEVGKGTGLGLSMVYGFVKQSGGHLRIYSEPGVgTTVRIYLP 116
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
281-505 |
3.00e-06 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 49.94 E-value: 3.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 281 FITDASHELRTPLAAIQGyaeLTRQ--DSsDLPPTTEYALARIESEA-----------------RRMTllvdellllsrl 341
Cdd:PRK11091 286 FISTISHELRTPLNGIVG---LSRIllDT-ELTAEQRKYLKTIHVSAitlgnifndiidmdkmeRRKL------------ 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 342 segeDLETEDLDLTDLVINavndaavaapthrwVKNL---------------PDEPV--WVNGDHARLHQLVSNLLTNAW 404
Cdd:PRK11091 350 ----QLDNQPIDFTDFLAD--------------LENLsglqaeqkglrfdlePLLPLphKVITDGTRLRQILWNLISNAV 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 405 VHTQPGvTVTIGITCHrtgpNAPCVELSVTDDGPDIDPEILPHLFDRF--VRASKSRSNGSGHGLGLAIVSSIVKAHRG- 481
Cdd:PRK11091 412 KFTQQG-GVTVRVRYE----EGDMLTFEVEDSGIGIPEDELDKIFAMYyqVKDSHGGKPATGTGIGLAVSKRLAQAMGGd 486
|
250 260
....*....|....*....|....*.
gi 685931000 482 -SVTAESGNGQT-VFRVRLPMIEQQI 505
Cdd:PRK11091 487 iTVTSEEGKGSCfTLTIHAPAVAEEV 512
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
388-499 |
4.73e-06 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 46.06 E-value: 4.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 388 DHARLHQLVSNLLTNAWVHTQPGV-TVTIGITCHRTGPnapCVELSVTDDGPDIDPEILPHLFDrfvrasksrsNGSGHG 466
Cdd:COG2172 31 DADDLVLAVSEAVTNAVRHAYGGDpDGPVEVELELDPD---GLEIEVRDEGPGFDPEDLPDPYS----------TLAEGG 97
|
90 100 110
....*....|....*....|....*....|...
gi 685931000 467 LGLAIVSSIVKahrgSVTAESGNGQTVFRVRLP 499
Cdd:COG2172 98 RGLFLIRRLMD----EVEYESDPGGTTVRLVKR 126
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
396-499 |
1.32e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 44.20 E-value: 1.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 396 VSNLLTNAWVHTQPGVTVTIGITCHRTGpnapcVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSI 475
Cdd:cd16948 10 IGQIVSNALKYSKQGGKIEIYSETNEQG-----VVLSIKDFGIGIPEEDLPRVFDKGFTGENGRNFQESTGMGLYLVKKL 84
|
90 100
....*....|....*....|....*
gi 685931000 476 VKAHRGSVTAESGNGQ-TVFRVRLP 499
Cdd:cd16948 85 CDKLGHKIDVESEVGEgTTFTITFP 109
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
381-502 |
1.43e-05 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 47.59 E-value: 1.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 381 EPVWVNGDHAR-----LHQLVSNLLTNAWVHTQPGvtvTIGITCHRTGPNapcVELSVTDDGPDIDPEILPhlfdrfvra 455
Cdd:COG3920 388 PDVELPADAAVplgliLNELVTNALKHAFLSGEGG---RIRVSWRREDGR---LRLTVSDNGVGLPEDVDP--------- 452
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 685931000 456 sksrsnGSGHGLGLAIVSSIVKAHRGSVTAESGNGqTVFRVRLPMIE 502
Cdd:COG3920 453 ------PARKGLGLRLIRALVRQLGGTLELDRPEG-TRVRITFPLAE 492
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
379-500 |
1.66e-05 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 47.54 E-value: 1.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 379 PDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGvTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRA--S 456
Cdd:PRK11107 396 PDVPDNVIGDPLRLQQIITNLVGNAIKFTESG-NIDILVELRALSNTKVQLEVQIRDTGIGISERQQSQLFQAFRQAdaS 474
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 685931000 457 KSRSNGsGHGLGLAIVSSIVKAHRG--SVTAESGNGQTvFRVRLPM 500
Cdd:PRK11107 475 ISRRHG-GTGLGLVITQKLVNEMGGdiSFHSQPNRGST-FWFHLPL 518
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
430-500 |
3.85e-05 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 45.84 E-value: 3.85e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 685931000 430 ELSVTDDGPDIDPEILPHLFDRFVRAsksRSNGSGhgLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPM 500
Cdd:PRK11073 282 RIDIEDNGPGIPPHLQDTLFYPMVSG---REGGTG--LGLSIARNLIDQHSGKIEFTSWPGHTEFSVYLPI 347
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
377-487 |
1.60e-04 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 44.24 E-value: 1.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 377 NLPDEPVWVnGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHrtgpnapCVELSVTDDGPDIDPEILPHLFDRFVRAS 456
Cdd:PRK10815 365 DISPEITFV-GEKNDFMEVMGNVLDNACKYCLEFVEISARQTDE-------HLHIVVEDDGPGIPESKRELIFDRGQRAD 436
|
90 100 110
....*....|....*....|....*....|.
gi 685931000 457 KSRSngsGHGLGLAIVSSIVKAHRGSVTAES 487
Cdd:PRK10815 437 TLRP---GQGLGLSVAREITEQYEGKISAGD 464
|
|
| HATPase_RsbW-like |
cd16936 |
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase ... |
395-476 |
2.84e-04 |
|
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.
Pssm-ID: 340413 [Multi-domain] Cd Length: 91 Bit Score: 39.94 E-value: 2.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 395 LVSNLLTNAWVHTQP-GVTVTIGITCHRTGpnaPCVELSVTDDGPDIDPEilphlfdrfvRASKSRSNGSGHGLGLAIVS 473
Cdd:cd16936 4 AVSEAVTNAVRHAYRhDGPGPVRLELDLDP---DRLRVEVTDSGPGFDPL----------RPADPDAGLREGGRGLALIR 70
|
...
gi 685931000 474 SIV 476
Cdd:cd16936 71 ALM 73
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
399-499 |
3.66e-04 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 42.30 E-value: 3.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 399 LLTNAWVHTQPG-VTVTIGITCHRtgpnapcVELSVTDDGPDIDPEILPhlfdrfvrasksrsngsGHGLGLAIVSSIVK 477
Cdd:COG4585 170 ALTNALKHAGATrVTVTLEVDDGE-------LTLTVRDDGVGFDPEAAP-----------------GGGLGLRGMRERAE 225
|
90 100
....*....|....*....|...
gi 685931000 478 AHRGSVTAESGNGQ-TVFRVRLP 499
Cdd:COG4585 226 ALGGTLTIGSAPGGgTRVRATLP 248
|
|
| ActS_PrrB_HisK |
NF033792 |
ActS/PrrB/RegB family redox-sensitive histidine kinase; This redox-responsive histidine kinase, ... |
285-471 |
7.16e-04 |
|
ActS/PrrB/RegB family redox-sensitive histidine kinase; This redox-responsive histidine kinase, found in alpha-proteobacteria, shows strong sequence conservation, including the notable motif [VA]AAAAHELGTPxTI. It always acts as a partner to an ActR/PrrA/RegA family global response regulator transcription factor in a two-component sensory transduction system. Lineage-specific names and gene symbols given to this histidine kinase reflect downstream regulator changes such as entry into stationary phase, anaerobic expression of photosynthesis genes, and survival of exposure to low pH.
Pssm-ID: 468186 [Multi-domain] Cd Length: 423 Bit Score: 42.12 E-value: 7.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 285 ASHELRTPLAAIQGYA-ELTRqdssDLPPTTEYA--LARIESEA-------RRMTLLVDEllllsrlsegEDLETEDLDL 354
Cdd:NF033792 209 AAHELGTPLATIALVAkELER----ELPDDPPLRedAELLRSQAercrdilRRLTSLGEE----------GDAHLDRLPL 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 355 TDLV-------------INAVNDAAVaapthrwvknlPDEPVwVNGDHARLHQLvSNLLTNAWVHTQPGVTVTIGITchr 421
Cdd:NF033792 275 SALIeeaaaphrgfgkeIEVVVAGDP-----------GEEPV-IRRNPEILYGL-GNLIENAVDFARSTVTVTASWD--- 338
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 685931000 422 tgpnAPCVELSVTDDGPDIDPEILPHLFDRFV---RASKSRSNGSGHGLGLAI 471
Cdd:NF033792 339 ----AESVTITIEDDGPGFPPDVLSRIGEPYVttrRGEERRPGGGGLGLGLFI 387
|
|
| PRK13560 |
PRK13560 |
hypothetical protein; Provisional |
395-500 |
1.01e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 106506 [Multi-domain] Cd Length: 807 Bit Score: 41.97 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 395 LVSNLLTNAWVHTQPGVTV-TIGITCHRTGPNApcVELSVTDDGPDidpeiLPHLFDrfVRASKSrsngsghgLGLAIVS 473
Cdd:PRK13560 715 IISELLSNALKHAFPDGAAgNIKVEIREQGDGM--VNLCVADDGIG-----LPAGFD--FRAAET--------LGLQLVC 777
|
90 100
....*....|....*....|....*..
gi 685931000 474 SIVKAHRGSVTAESGNGqTVFRVRLPM 500
Cdd:PRK13560 778 ALVKQLDGEIALDSRGG-ARFNIRFPM 803
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-486 |
1.61e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 38.29 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 388 DHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSrsngsGHGL 467
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIEGRPSDVGEVRIRVEADQDGRIVLIVCDNGKGFPREMRHRATEPYVTTRPK-----GTGL 75
|
90
....*....|....*....
gi 685931000 468 GLAIVSSIVKAHRGSVTAE 486
Cdd:cd16944 76 GLAIVKKIMEEHGGRISLS 94
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
429-499 |
3.17e-03 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 38.72 E-value: 3.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 685931000 429 VELSVTDDGPDIDP------------------------EILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHRGSVT 484
Cdd:cd16916 83 VVIEVSDDGRGIDRekirekaierglitadeaatlsddEVLNLIFAPGFSTAEQVTDVSGRGVGMDVVKRSIESLGGTIE 162
|
90
....*....|....*.
gi 685931000 485 AESGNGQ-TVFRVRLP 499
Cdd:cd16916 163 VESEPGQgTTFTIRLP 178
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