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Conserved domains on  [gi|686156298|ref|WP_031788040|]
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DNA polymerase III subunit gamma/tau [Staphylococcus argenteus]

Protein Classification

DNA polymerase III subunit gamma/tau( domain architecture ID 11481115)

DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme; gamma and tau subunits are isoforms and either one or both may be present in the holoenzyme; gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-563 0e+00

DNA polymerase III subunits gamma and tau; Validated


:

Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 853.01  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK05563   1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK05563  81 AITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK05563 161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 241 TGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTADK----------DSDYRALM-N 309
Cdd:PRK05563 241 TGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPEleildestenDELFKELSeK 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 310 LDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLAElikgqsqvgtnvAEPVQIAATPSSDVLLQRMEQLEQELKVL 389
Cdd:PRK05563 321 LDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLCE------------QAAASPEYDTELEVLLQRVEQLEQELKQL 388
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 390 KAQGVTAAPTQKTSKKPIRGMQKSKNAFSMQQIAKVLDRANKADIKLLKDHWQEVIDHAKNNdKKSLVSLLQNSEPVAAS 469
Cdd:PRK05563 389 KAQPVGVAPEQKEKKKEKKKNKKKKYKVPRGKIYKVLKEATRQDLELLKNVWGEILESLKAQ-RKSLRALLVNSEPVAAS 467
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 470 EDHVLVKFEEEIHCEIVNKDDEKRNNIESVVCNIVNKNVKVVGVPSDQWQRVRTEYLQNRKHDNDEMPKQQVQqtDIAQK 549
Cdd:PRK05563 468 EDTVVLAFEYEIHFEKAMLDKELNDTIENILSKLLGKSVEIVAVPEDEWQKIREEFLQKHKNEEEEEEEEEEL--PLIPE 545
                        570
                 ....*....|....
gi 686156298 550 AKDLFGEETVHVID 563
Cdd:PRK05563 546 AKELFGEDLVEIID 559
 
Name Accession Description Interval E-value
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-563 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 853.01  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK05563   1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK05563  81 AITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK05563 161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 241 TGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTADK----------DSDYRALM-N 309
Cdd:PRK05563 241 TGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPEleildestenDELFKELSeK 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 310 LDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLAElikgqsqvgtnvAEPVQIAATPSSDVLLQRMEQLEQELKVL 389
Cdd:PRK05563 321 LDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLCE------------QAAASPEYDTELEVLLQRVEQLEQELKQL 388
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 390 KAQGVTAAPTQKTSKKPIRGMQKSKNAFSMQQIAKVLDRANKADIKLLKDHWQEVIDHAKNNdKKSLVSLLQNSEPVAAS 469
Cdd:PRK05563 389 KAQPVGVAPEQKEKKKEKKKNKKKKYKVPRGKIYKVLKEATRQDLELLKNVWGEILESLKAQ-RKSLRALLVNSEPVAAS 467
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 470 EDHVLVKFEEEIHCEIVNKDDEKRNNIESVVCNIVNKNVKVVGVPSDQWQRVRTEYLQNRKHDNDEMPKQQVQqtDIAQK 549
Cdd:PRK05563 468 EDTVVLAFEYEIHFEKAMLDKELNDTIENILSKLLGKSVEIVAVPEDEWQKIREEFLQKHKNEEEEEEEEEEL--PLIPE 545
                        570
                 ....*....|....
gi 686156298 550 AKDLFGEETVHVID 563
Cdd:PRK05563 546 AKELFGEDLVEIID 559
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
3-347 0e+00

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 515.96  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298    3 YQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGI 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   83 TQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKI 162
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  163 PPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNVTG 242
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  243 SVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTA----------DKDSDYRALMNLDL 312
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTpsnllavlesEQEFLKELALKLSL 320
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 686156298  313 EMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLA 347
Cdd:TIGR02397 321 EFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-348 1.66e-162

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 466.21  E-value: 1.66e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQAlyrmyrPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:COG2812    1 MSYQV------PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCR 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDA-ASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEP 159
Cdd:COG2812   75 AIAAGSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEP 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 160 HKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGdgtltLQDAln 239
Cdd:COG2812  155 QKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAFG-----LLDR-- 227
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 240 vtgsvhDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTADKD-----SDYRALM-----N 309
Cdd:COG2812  228 ------RELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAellvnEDERERLqelarR 301
                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 686156298 310 LDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLAE 348
Cdd:COG2812  302 LSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
20-179 5.11e-56

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 185.49  E-value: 5.11e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   20 GQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGITQGTNSDVIEIDAASNN 99
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  100 -GVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAI 178
Cdd:pfam13177  81 iKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160

                  .
gi 686156298  179 S 179
Cdd:pfam13177 161 S 161
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
178-242 3.06e-24

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 95.65  E-value: 3.06e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 686156298 178 ISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNVTG 242
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
41-176 6.17e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 49.29  E-value: 6.17e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298    41 YIFSGPRGTGKTSIAKVFAKAINCLNSN----DGEPcnecaICKGITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYaps 116
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPGGGviyiDGED-----ILEEVLDQLLLIIVGGKKASGSGELRLRLALALARK--- 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 686156298   117 eSKYKVYIIDEVHMLTTGAFNALL--------KTLEEPPAHAIFILATTEPHKIPPTIISRaqRFDFK 176
Cdd:smart00382  77 -LKPDVLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDLGPALLRR--RFDRR 141
 
Name Accession Description Interval E-value
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-563 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 853.01  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK05563   1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK05563  81 AITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK05563 161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 241 TGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTADK----------DSDYRALM-N 309
Cdd:PRK05563 241 TGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPEleildestenDELFKELSeK 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 310 LDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLAElikgqsqvgtnvAEPVQIAATPSSDVLLQRMEQLEQELKVL 389
Cdd:PRK05563 321 LDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLCE------------QAAASPEYDTELEVLLQRVEQLEQELKQL 388
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 390 KAQGVTAAPTQKTSKKPIRGMQKSKNAFSMQQIAKVLDRANKADIKLLKDHWQEVIDHAKNNdKKSLVSLLQNSEPVAAS 469
Cdd:PRK05563 389 KAQPVGVAPEQKEKKKEKKKNKKKKYKVPRGKIYKVLKEATRQDLELLKNVWGEILESLKAQ-RKSLRALLVNSEPVAAS 467
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 470 EDHVLVKFEEEIHCEIVNKDDEKRNNIESVVCNIVNKNVKVVGVPSDQWQRVRTEYLQNRKHDNDEMPKQQVQqtDIAQK 549
Cdd:PRK05563 468 EDTVVLAFEYEIHFEKAMLDKELNDTIENILSKLLGKSVEIVAVPEDEWQKIREEFLQKHKNEEEEEEEEEEL--PLIPE 545
                        570
                 ....*....|....
gi 686156298 550 AKDLFGEETVHVID 563
Cdd:PRK05563 546 AKELFGEDLVEIID 559
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
3-347 0e+00

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 515.96  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298    3 YQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGI 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   83 TQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKI 162
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  163 PPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNVTG 242
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  243 SVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTA----------DKDSDYRALMNLDL 312
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTpsnllavlesEQEFLKELALKLSL 320
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 686156298  313 EMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLA 347
Cdd:TIGR02397 321 EFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-348 1.66e-162

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 466.21  E-value: 1.66e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQAlyrmyrPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:COG2812    1 MSYQV------PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCR 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDA-ASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEP 159
Cdd:COG2812   75 AIAAGSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEP 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 160 HKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGdgtltLQDAln 239
Cdd:COG2812  155 QKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAFG-----LLDR-- 227
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 240 vtgsvhDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTADKD-----SDYRALM-----N 309
Cdd:COG2812  228 ------RELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAellvnEDERERLqelarR 301
                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 686156298 310 LDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLAE 348
Cdd:COG2812  302 LSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
1-559 2.84e-131

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 399.96  E-value: 2.84e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSND-GEPCNECaic 79
Cdd:PRK07133   3 MKYKALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCSHKTDlLEPCQEC--- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  80 kgITQGTNS-DVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTE 158
Cdd:PRK07133  80 --IENVNNSlDIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTE 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 159 PHKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDAL 238
Cdd:PRK07133 158 VHKIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNKITLKNVE 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 239 NVTGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIM-NKTADKD----SDYRALMNL--D 311
Cdd:PRK07133 238 ELFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLVKEFIIfNKTKDNSlleyYSEEDLEKLkiD 317
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 312 LEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLAELiKGQSQVGTNVAEPVQIAATPSSDVLLQRMEQLEQELKVLKA 391
Cdd:PRK07133 318 DDFAYKFIEILFDLLKDLKISDNPNDTLEILIIKLLAL-SELEEEDENEIKFKKIEENSIDNLDIKEKKIENENDIEGKS 396
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 392 QGVTAAPTQKTSKKPIRGMQKSKNAF-SMQQIAKVLDRANKADIKLLKDHWQEVIDHAKNNDKKSL--VSLLQNSEPVAA 468
Cdd:PRK07133 397 DTKNLEEGFETKDNKNKNSSFINKTEnILTNSPLKDELLEKTTEIINIENPQEFEFGQIGNDIISTeiAQLDENQNLIDT 476
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 469 SEDHVLVKFEEEIHCEIVNKDDE--KRNNIESVVCNIVNKNVKVVGVPSDQWQRVRTEYLQNRKHDNDEMPKQQVQQTDI 546
Cdd:PRK07133 477 GEFDLENNFSNSFNPENGNKIDEniNETFDTSTISANLSENKTNFAQSFNNKDTNLINSEIPIDLIKDTITINNSQKNVK 556
                        570
                 ....*....|...
gi 686156298 547 AQKAKDLFGEETV 559
Cdd:PRK07133 557 KNGNKDYLSVEEV 569
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
1-565 2.07e-125

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 380.31  E-value: 2.07e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSN-DGEPCNECAIC 79
Cdd:PRK14950   1 MTVQVLYRKWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTNDpKGRPCGTCEMC 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  80 KGITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEP 159
Cdd:PRK14950  81 RAIAEGSAVDVIEMDAASHTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 160 HKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALN 239
Cdd:PRK14950 161 HKVPATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGEISLSQVQS 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 240 VTGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDT-IMNKTADKD-----SDYRALM----- 308
Cdd:PRK14950 241 LLGISGDEEVKALAEALLAKDLKAALRTLNAVAADGADLRQFTRDLVEYLRQVmLLNSGADRSlldltADEKAALqkvsq 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 309 NLDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKL------AELIKGQSQVGTNVAEPVQIAATPSSDVLLQRMEQL 382
Cdd:PRK14950 321 IANLEALTKWVKAFSQLDFQLRTTSYGQLPLELAVIEAllvpvpAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPK 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 383 EQELKVLKAQGVT-------------AAPTQKTSKKPIRGMQKSKNAFSMQQIAKVLDrANKADIKLLKDHWQEVIDHAK 449
Cdd:PRK14950 401 EPVRETATPPPVPprpvappvphtpeSAPKLTRAAIPVDEKPKYTPPAPPKEEEKALI-ADGDVLEQLEAIWKQILRDVP 479
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 450 NNDKKslVSLLQNS--EPVAASEDHVLVKFEEEIHCEIVNKdDEKRNNIESVVCNIVNKNVKVVGVPSDQWQRVRTEYLQ 527
Cdd:PRK14950 480 PRSPA--VQALLSSgvRPVSVEKNTLTLSFKSKFHKDKIEE-PENRKITEELLSNFVGKTCAVRCTIEEKSEEPGDLREQ 556
                        570       580       590
                 ....*....|....*....|....*....|....*...
gi 686156298 528 NRKHDNDEMPKQqvqqtdiaqkAKDLFGEETVHVIDEE 565
Cdd:PRK14950 557 IREARKDHLVKA----------AQNIFDAQIISVEEKN 584
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
1-479 9.00e-125

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 378.32  E-value: 9.00e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK14965   1 MSYLVLARKYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHAFLFTGARGVGKTSTARILAKALNCEQGLTAEPCNVCPPCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14965  81 EITEGRSVDVFEIDGASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK14965 161 KVPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDVAEL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 241 TGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTADKDSD-----------YRALMN 309
Cdd:PRK14965 241 LGVVDRRLLLDISAAVFGRDTRALLEIVERVDEFGYNMRQFCQELIDHLRNLVVLRAVGEPGDlldlseaelaeLRAQAA 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 310 -LDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLAELIKGqSQVGTNVAEPVQI---AATPSSDVLLQRMEQLEQE 385
Cdd:PRK14965 321 aADAADLQRHLTLLLRAEGEMAHASFPRLVLEMALLKMATLAPG-APVSELLDRLEALergAPAPPSAAWGAPTPAAPAA 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 386 LKVLKAQGVT-AAPTQKTSKKPIRGMQKSKNAFSMQQIAKVLDRANKAdikllkDHWQEVIDHAKnNDKKSLVSLLQNSE 464
Cdd:PRK14965 400 PPPAAAPPVPpAAPARPAAARPAPAPAPPAAAAPPARSADPAAAASAG------DRWRAFVAFVK-GKKPALGASLEQGS 472
                        490
                 ....*....|....*
gi 686156298 465 PVAASEDHVLVKFEE 479
Cdd:PRK14965 473 PLGVSAGLLEIGFPE 487
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
1-454 3.80e-122

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 368.77  E-value: 3.80e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK14953   1 MMYIPFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14953  81 EIDKGSFPDLIEIDAASNRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYD 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK14953 161 KIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKVTIKVVEEF 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 241 TGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTADKDS------DYRALMNLDLEM 314
Cdd:PRK14953 241 LGIVSQESVRKFLNLLLESDVDEAIKFLRTLEEKGYNLNKFWKQLEEEIRNILLNKSLKNPEevfqveDFYRKLEKPLEA 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 315 LYHMIDLINDTLVSIR-FSVNQNVHFEVLLVKLAELIKGQSQVGtNVAEPVQIAATPssdvllQRMEQLEQELKVLKAQG 393
Cdd:PRK14953 321 LLYLEDVINKAFSEARtRDPLRAYELAILKLLYVKDIVPISELL-KEGSKQETKEQP------EKKEEEKEELDIDKIIL 393
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 686156298 394 VTAAPTQKTSKKPIRGMQ-KSKNAFSMQQIAKVLDRANKADIKLLK----DHWQEVIDHAKNNDKK 454
Cdd:PRK14953 394 QIIKNEGKIISAILKNAEiKEEEGKITIKVEKSEEDTLDLEIKSIKkyfpFIEFEEVKKEKEKEKE 459
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
3-407 3.46e-120

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 362.17  E-value: 3.46e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   3 YQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLN-SNDGEPCNECAICKG 81
Cdd:PRK06305   4 YQVSSRKYRPQTFSEILGQDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQNpTEDQEPCNQCASCKE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  82 ITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHK 161
Cdd:PRK06305  84 ISSGTSLDVLEIDGASHRGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHK 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 162 IPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNVT 241
Cdd:PRK06305 164 IPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKSLDPDSVAKAL 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 242 GSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTADKDSdyRALMNLDLEMLYHMIDL 321
Cdd:PRK06305 244 GLLSQDSLYTLDEAITTQNYAQALEPVTDAMNSGVAPAHFLHDLTLFFRNILLKQYNKQLS--SVATKYSSEQLLEIIDF 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 322 INDTLVSIRFSVNQNVHFEVLLVKLaelikgqsqvgtnvaepVQIAATPSSDVLLQRMEQLEQELKVL--KAQGVTAAPT 399
Cdd:PRK06305 322 LGESAKHIQLTIFEKTFLETVIIHL-----------------IRIYQRPTLSQLVSQIKSPAFTQLRLesCPPQIKSSNS 384

                 ....*...
gi 686156298 400 QKTSKKPI 407
Cdd:PRK06305 385 QQTVSSPQ 392
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
1-445 2.57e-119

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 365.82  E-value: 2.57e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSnDG---EPCNECA 77
Cdd:PRK14948   1 MAYEPLHHKYRPQRFDELVGQEAIATTLKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNCLNS-DKptpEPCGKCE 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  78 ICKGITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATT 157
Cdd:PRK14948  80 LCRAIAAGNALDVIEIDAASNTGVDNIRELIERAQFAPVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATT 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 158 EPHKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQaIAFGDGTLTLQDA 237
Cdd:PRK14948 160 DPQRVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQ-LSLLPGPITPEAV 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 238 LNVTGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTADKDSDYRALM--------- 308
Cdd:PRK14948 239 WDLLGAVPEQDLLNLLKALASNDPESLLDSCRQLLDRGREPLAILQGLAAFYRDLLLAKTAPNRPDLVAVSqqtwdelck 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 309 ---NLDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLAelikGQSQVGTNVAEPVQIAATPSSDVLLQRMEQLEQE 385
Cdd:PRK14948 319 lakQINLERILQWQQHLKGSEYQLKNSTQPRLWLEVTLLGLL----PSAFISEIANASAPANPTPAPNPSPPPAPIQPSA 394
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 386 LKVLKAQGVTAAPTQKTSKKPIrgmQKSKNAFSMQQIAKvlDRANKADIKLLKDHWQEVI 445
Cdd:PRK14948 395 PKTKQAATTPSPPPAKASPPIP---VPAEPTEPSPTPPA--NAANAPPSLNLEELWQQIL 449
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
4-286 3.19e-115

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 350.22  E-value: 3.19e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   4 QALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGIT 83
Cdd:PRK14962   2 EALYRKYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSID 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  84 QGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIP 163
Cdd:PRK14962  82 EGTFMDVIELDAASNRGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVP 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 164 PTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNVTGS 243
Cdd:PRK14962 162 PTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHEALGL 241
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 686156298 244 VHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMI 286
Cdd:PRK14962 242 IPIEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLIQQAI 284
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
2-487 1.15e-112

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 348.30  E-value: 1.15e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   2 NYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLN-SNDGEPCNECAICK 80
Cdd:PRK14971   3 NYIVSARKYRPSTFESVVGQEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCQNlTADGEACNECESCV 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14971  83 AFNEQRSYNIHELDAASNNSVDDIRNLIEQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKH 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALnv 240
Cdd:PRK14971 163 KILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVI-- 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 241 tgsvhdEALNHLFED--------IVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTAD-----------KD 301
Cdd:PRK14971 241 ------ENLNILDYDyyfrltdaLLAGKVSDSLLLFDEILNKGFDGSHFITGLASHFRDLLVCKDAAtlqllevgesiRQ 314
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 302 SDYRALMNLDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLAELIKG----------------------------- 352
Cdd:PRK14971 315 RYLEQAQKCPMSFLYRALKLCNQCDLNYRASKNKRLLVELTLIQLAQLTQKgddasggrgpkqhikpvftqpaaapqpsa 394
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 353 -------QSQVGTNVAEPVQIAATPSSDVLLQRMEQLEQELKVLKAQGV--TAAPTQKTSKKPIRGMQKSKNAFSMQQIA 423
Cdd:PRK14971 395 aaaaspsPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPPSTApqAVRPAQFKEEKKIPVSKVSSLGPSTLRPI 474
                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 686156298 424 KVLDRANKADIKL--------------LKDHWQEvIDHAKNNDKKSLVSLLQNSEPVAASEDHVLVKFEEEIHCEIVN 487
Cdd:PRK14971 475 QEKAEQATGNIKEaptgtqkeifteedLQYYWQE-FAGTRPQEEKALKETMINCRPKLLNGTTFEVAVDNELQEKELT 551
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
1-286 1.85e-110

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 343.77  E-value: 1.85e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK07994   1 MSYQVLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK07994  81 EIEQGRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK07994 161 KLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAM 240
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 686156298 241 TGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMI 286
Cdd:PRK07994 241 LGTLDDDQALSLLEALVEGDGERVMALINQLAERGPDWEGLLVELL 286
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
1-349 3.42e-108

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 335.20  E-value: 3.42e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK06647   1 MSYRGTATKRRPRDFNSLEGQDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCGECSSCK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK06647  81 SIDNDNSLDVIEIDGASNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK06647 161 KLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDSDITLEQIRSK 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 241 TGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTADK---------DSDYRALMNLD 311
Cdd:PRK06647 241 MGLTGDEFLEKLASSILNEDAKELLCVLDSVFLSGVSVEQFLLDCIEFFRELLFLKHGIKneafigikaERLPEKLREFD 320
                        330       340       350
                 ....*....|....*....|....*....|....*...
gi 686156298 312 LEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLAEL 349
Cdd:PRK06647 321 LSQIERAISVLLETYRDLQFSVNPRYELEINFSKILRL 358
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
1-498 3.18e-105

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 328.73  E-value: 3.18e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK05896   1 MSEITFYRKYRPHNFKQIIGQELIKKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK05896  81 SINTNQSVDIVELDAASNNGVDEIRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK05896 161 KIPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSEIDIEDINKT 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 241 TGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKtadKDSDYRALMNLDLEMLyHMID 320
Cdd:PRK05896 241 FGLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLLIDLLVYQ---KTKNINLLKKLSKEQL-KTLN 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 321 LINDTLVSIRFSVNqnvhfeVLLVKLAELIKGQSQVGTNVAEpVQIAATPSSDVLLQRMEQLEQELKVlKAQGVTAAPTQ 400
Cdd:PRK05896 317 LEKQKLLSIEFNTN------FLLNNFVSLINRLKASVNQVFE-FEIYLYKIINANPDKLENKKIEISI-KPEKKTINNSQ 388
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 401 KTSKKPIrgmqksknafsmqqiaKVLDRANKADIKLLKDHWQEVIDHAKNNDkkslvsllQNSEPVAASEDHVLVKFEEE 480
Cdd:PRK05896 389 IITTKKI----------------NIVEESNKNSVHFDTLYKTKIFYHKKKIN--------QNNKEQDIKKEELLEKEFVK 444
                        490
                 ....*....|....*...
gi 686156298 481 IHcEIVNKDDEKRNNIES 498
Cdd:PRK05896 445 KS-EKIPKNDELLDNLEL 461
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
3-265 4.58e-103

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 323.01  E-value: 4.58e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   3 YQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSnDG------EPCNEC 76
Cdd:PRK09111  11 YRVLARKYRPQTFDDLIGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEGP-DGdggptiDLCGVG 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  77 AICKGITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILAT 156
Cdd:PRK09111  90 EHCQAIMEGRHVDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFAT 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 157 TEPHKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLT--- 233
Cdd:PRK09111 170 TEIRKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIAHGAGEVTaea 249
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 686156298 234 ------LQDalnvTGSVHDealnhLFEDIVQGDVQSSF 265
Cdd:PRK09111 250 vrdmlgLAD----RARVID-----LFEALMRGDVAAAL 278
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
1-482 1.25e-102

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 322.66  E-value: 1.25e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDG--------EP 72
Cdd:PRK14954   1 MSYQVIARKYRPSKFADITAQEHITHTIQNSLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDpvylqevtEP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  73 CNECAICKGITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIF 152
Cdd:PRK14954  81 CGECESCRDFDAGTSLNISEFDAASNNSVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 153 ILATTEPHKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGT- 231
Cdd:PRK14954 161 IFATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIAFSVGSe 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 232 ----LTLQDALNVTGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKE----VNRLIND-----MIYFVRDT--IMNK 296
Cdd:PRK14954 241 aekvIAYQGVAELLNYIDDEQFFDVTDAIAENDAVKMLEVARFVIDNGYDeqdfLEKLIEHfrnflVLYNLRSTrlIERP 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 297 TADKDSDYRALMNLDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLAELIKGQSQVGTNVAE-------------- 362
Cdd:PRK14954 321 ESVKERYQQSAGGLTPAAVMQMTDFLMKTQGELKFQFEYQFRFELALLRLIELVRNDGGVAPSPAGspdvkkkapepdlp 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 363 -----------------------------PVQIAATPSSdVLLQRMEQLEQELKVLKAQGVT--AAPTQKTSKKPIRGMQ 411
Cdd:PRK14954 401 qpdrhpgpakpeapgarpaelpspasaptPEQQPPVARS-APLPPSPQASAPRNVASGKPGVdlGSWQGKFMNFTRNGSR 479
                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 686156298 412 KSKNAFSMQQIAKVLDRANKADIKLLKDHWQEVIDHAKNNDKKSLVSLLQNSEPVAASEDHVLV-------KFEEEIH 482
Cdd:PRK14954 480 KQPVQASSSDAAQTGVFEGVAELEKLRMEWNQFLEHLLKKGQKVLVTHLRSCELTSCSPHGVVVmtccrkfSYEELMQ 557
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
1-365 3.78e-100

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 308.75  E-value: 3.78e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDG--------EP 72
Cdd:PRK14955   1 MSYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDadylqevtEP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  73 CNECAICKGITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIF 152
Cdd:PRK14955  81 CGECESCRDFDAGTSLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 153 ILATTEPHKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAF----- 227
Cdd:PRK14955 161 IFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQVIAFsvese 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 228 GDGTLTLQDALNVTGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIM-----------NK 296
Cdd:PRK14955 241 GEGSIRYDKVAELLNYIDDEHFFAVTDAVADGDAVAMLDVAQFVIRNGYDEQDFLEKLIEHLRNFLVvhnlrstrlveRP 320
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 686156298 297 TADKDSDYRALMNLDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLAELIKGQSQVGTNVAEPVQ 365
Cdd:PRK14955 321 DAVRERYERDAAKFSPEVIMQMTDLLLQTQKELKFQFEYQFRFELALLKLIEIGHPAPTAAAAPTGGAQ 389
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
1-260 1.26e-99

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 317.42  E-value: 1.26e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK08691   1 MAYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK08691  81 QIDAGRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK08691 161 KVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQM 240
                        250       260
                 ....*....|....*....|
gi 686156298 241 TGSVHDEALNHLFEDIVQGD 260
Cdd:PRK08691 241 IGAVDKQYLYELLTGIINQD 260
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
1-260 2.78e-99

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 310.91  E-value: 2.78e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK14969   1 MSYQVLARKWRPKSFSELVGQEHVVRALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14969  81 EIDSGRFVDLIEVDAASNTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK14969 161 KIPVTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVNESEVRAM 240
                        250       260
                 ....*....|....*....|
gi 686156298 241 TGSVHDEALNHLFEDIVQGD 260
Cdd:PRK14969 241 LGAIDQDYLFALLEALLAQD 260
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
2-348 2.14e-97

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 304.56  E-value: 2.14e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   2 NYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKG 81
Cdd:PRK14956   4 THEVLSRKYRPQFFRDVIHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  82 ITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHK 161
Cdd:PRK14956  84 ITKGISSDVLEIDAASNRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHK 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 162 IPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNVT 241
Cdd:PRK14956 164 IPETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLTGVKIRKMI 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 242 GSVHDEALNHLFEDIVQGDVQS-SFKKYHQFIAEGKEVNRLINDMIYFVR--DTIMNKTADKDS-------------DYR 305
Cdd:PRK14956 244 GYHGIEFLTSFIKSLIDPDNHSkSLEILESLYQEGQDIYKFLWDSIEFTHtlNLIRDSLADRESvnfpkedlqkmksDFE 323
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 686156298 306 AL----MNLDLEMLYHMIDLINdtLVSIRFSVNQNVHFEVLLVKLAE 348
Cdd:PRK14956 324 NVdsskLNFLSGKLFEIYEKIK--TIRLRNSFEIKVFTEIQIKKLVE 368
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
5-275 4.61e-97

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 304.46  E-value: 4.61e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   5 ALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINClNSNDGEPCNECAICKGITQ 84
Cdd:PRK14963   3 ALYQRARPITFDEVVGQEHVKEVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNC-SGEDPKPCGECESCLAVRR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  85 GTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPP 164
Cdd:PRK14963  82 GAHPDVLEIDAASNNSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPP 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 165 TIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGdGTLTLQDALNVTGSV 244
Cdd:PRK14963 162 TILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERLLALG-TPVTRKQVEEALGLP 240
                        250       260       270
                 ....*....|....*....|....*....|.
gi 686156298 245 HDEALNHLFEDIVQGDVQSSFKKYHQFIAEG 275
Cdd:PRK14963 241 PQERLRGIAAALAQGDAAEALSGAAQLYRDG 271
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
4-559 1.34e-94

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 298.87  E-value: 1.34e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   4 QALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGIT 83
Cdd:PRK08451   2 QALALKYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPCDTCIQCQSAL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  84 QGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIP 163
Cdd:PRK08451  82 ENRHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLP 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 164 PTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNVTGS 243
Cdd:PRK08451 162 ATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADMLGL 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 244 VHDEALNHLFEDIVQGDVQSSFKKYHQFiaEGKEVNRLINDMIYFVRDtimnKTADKDSDYRALMnldLEMLYHMIDLIN 323
Cdd:PRK08451 242 LDPSKLEDFFQAILNQDKEKLFELLKEL--EDYEAEMVLDEMMLFLKE----KFLSKDSEFSILL---YERFFRILSSAK 312
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 324 DTLvsirfSVNQNVHFEVLLV--KLAELIKGQSqvgtnvaepvqiaatpssdvLLQRMEQLEQELKVLKAQGVTAAPTQK 401
Cdd:PRK08451 313 SLL-----KEGADDGFVLLLMlfKMKEALKLKE--------------------IDDAIEELEQEKTTAIIPLNTPAPIIP 367
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 402 TSKKPIRGMQKSKNAFSMQQiAKVLDRaN-------KADIKL--LKDHWQEVIDHAKNNDKKslvsLLQNSEPVAASEDH 472
Cdd:PRK08451 368 NTEKEEAKDRIFKNLFEQLL-DKIYDR-NyelgecfEKNIRFidFDSNTLTWESNAQGEDKE----LLRKGFKIIKEIVD 441
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 473 VLVKFEEEIhceIVNKDDEKRNNIESVVCNIVNKNVKVVGVPS-------DQWQRVRTEYLQNRKHDNDEMPKQQVQQTD 545
Cdd:PRK08451 442 EVFGKGAKI---KIQKALKSAENPLQSLKEFKPSNEKKKIDTEstaemleEEAKKDDEEVQETQLKEATELQEFMINNED 518
                        570
                 ....*....|....
gi 686156298 546 IAQKAKDLFGEETV 559
Cdd:PRK08451 519 LIEEAKELFGIKSI 532
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1-260 1.63e-92

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 298.33  E-value: 1.63e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSnDG------EPCN 74
Cdd:PRK12323   1 MSYQVLARKWRPRDFTTLVGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCTGA-DGeggitaQPCG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  75 ECAICKGITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFIL 154
Cdd:PRK12323  80 QCRACTEIDAGRFVDYIEMDAASNRGVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFIL 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 155 ATTEPHKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTL 234
Cdd:PRK12323 160 ATTDPQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGNVSE 239
                        250       260
                 ....*....|....*....|....*.
gi 686156298 235 QDALNVTGSVHDEALNHLFEDIVQGD 260
Cdd:PRK12323 240 EAVRGMLGAIDQSYLVRLLDALAAED 265
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
1-260 2.16e-92

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 295.86  E-value: 2.16e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSnDG------EPCN 74
Cdd:PRK14951   1 MSYLVLARKYRPRSFSEMVGQEHVVQALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCQGP-DGqggitaTPCG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  75 ECAICKGITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFIL 154
Cdd:PRK14951  80 VCQACRDIDSGRFVDYTELDAASNRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVL 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 155 ATTEPHKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTL 234
Cdd:PRK14951 160 ATTDPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGSGQLQE 239
                        250       260
                 ....*....|....*....|....*.
gi 686156298 235 QDALNVTGSVHDEALNHLFEDIVQGD 260
Cdd:PRK14951 240 AAVRQMLGSVDRSHVFRLIDALAQGD 265
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
8-349 3.88e-91

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 284.46  E-value: 3.88e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   8 RMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEpcnecaickgitQGTN 87
Cdd:PRK14970   9 RKYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQPGYDDPN------------EDFS 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  88 SDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTII 167
Cdd:PRK14970  77 FNIFELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTIL 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 168 SRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNVTGSVHDE 247
Cdd:PRK14970 157 SRCQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENLNILDYD 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 248 ALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKT-----------ADKDSDYRALMNLDLEMLY 316
Cdd:PRK14970 237 TYINVTDLILENKIPELLLAFNEILRKGFDGHHFIAGLASHFRDLMVSKTpatiallevgeQAKKRYEVQSQKVSQSFLL 316
                        330       340       350
                 ....*....|....*....|....*....|...
gi 686156298 317 HMIDLINDTLVSIRFSVNQNVHFEVLLVKLAEL 349
Cdd:PRK14970 317 SGIDIANDCDLKYKLSKNQRLLVELALMQLASI 349
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
1-280 3.99e-91

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 300.10  E-value: 3.99e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK14949   1 MSYQVLARKWRPATFEQMVGQSHVLHALTNALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGVTATPCGVCSSCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14949  81 EIAQGRFVDLIEVDAASRTKVDDTRELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK14949 161 KLPVTVLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFEAEALTLLAKAANGSMRDALSLTDQAIAFGGGQVMLTQVQTM 240
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 686156298 241 TGSVHDEALNHLFEDIVQGDV----QSSfKKYHQFIAEGKEVNR 280
Cdd:PRK14949 241 LGSIDEQHVIALLKALTDADIgvlmQTC-AQVLAFGADAQEVLR 283
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
10-303 3.77e-90

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 286.30  E-value: 3.77e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  10 YRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGITQGTNSD 89
Cdd:PRK14964   7 YRPSSFKDLVGQDVLVRILRNAFTLNKIPQSILLVGASGVGKTTCARIISLCLNCSNGPTSDPCGTCHNCISIKNSNHPD 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  90 VIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISR 169
Cdd:PRK14964  87 VIEIDAASNTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVTIISR 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 170 AQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNVTGSVHDEAL 249
Cdd:PRK14964 167 CQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNKISEKSVRDLLGCVDKHIL 246
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 686156298 250 NHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLIN--DMIYFVRDTIMNKTADKDSD 303
Cdd:PRK14964 247 EDLVEAILLGDAQSALNVFRELCNTSNPVIILEGmlQIIYEICYFSITKEIDFLLG 302
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
1-296 1.07e-88

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 278.23  E-value: 1.07e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK14961   1 MNYQILARKWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14961  81 EIEKGLCLDLIEIDAASRTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK14961 161 KIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGNINIKNVTDM 240
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 686156298 241 TGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNK 296
Cdd:PRK14961 241 LGLLNEKQSFLLTDALLKKDSKKTMLLLNKISSIGIEWENILIEMLRFLHHISMSQ 296
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
4-490 3.57e-87

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 281.00  E-value: 3.57e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   4 QALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGIT 83
Cdd:PRK14952   1 MALYRKYRPATFAEVVGQEHVTEPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESCVALA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  84 QGTNS--DVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHK 161
Cdd:PRK14952  81 PNGPGsiDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 162 IPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIA-FGDGTLTLQDALNV 240
Cdd:PRK14952 161 VLPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAgAADTHVTYQRALGL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 241 TGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTAdKDSDYRALMNLDLEMLYHMID 320
Cdd:PRK14952 241 LGATDVALIDDAVDALAADDAAALFGAIESVIDAGHDPRRFATDLLERFRDLIVLQAV-PDAAARGVVDAPEDVLERMRE 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 321 LindtlvSIRFSVNQNVHF-EVLLVKLAEL---IKGQSQVGTNVAEPVQIAATPSSDVLLQRMEQLEQEL-KVLKAQGVT 395
Cdd:PRK14952 320 Q------AARIGLATLTRYaEVVQAGLGEMrgaTAPRLLLEVVCARLLLPSASDAESALLQRVERIETRLdMSIPANLLH 393
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 396 AAPTQKTSKKPIRGMQKSKNAFSMQQIAKVLDRANKADIKLLKDHWQEVIDHAKNNDKKSLVsLLQNSEPVAASEDHVLV 475
Cdd:PRK14952 394 NAPQAAPAPSAAAPEPKHQPAPEPRPVLAPTPASGEPNAAAVRSMWSTVRDKVRQRSRTTEV-MLAGATVRALEGNTLVL 472
                        490
                 ....*....|....*....
gi 686156298 476 KFEEEIH----CEIVNKDD 490
Cdd:PRK14952 473 THESAPLarrlSEQRNADV 491
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
1-312 2.98e-86

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 280.03  E-value: 2.98e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK14959   1 MSHASLTARYRPQTFAEVAGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14959  81 KVTQGMHVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK14959 161 KFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESRLTIDGARGV 240
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 686156298 241 TGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTADKdsdyRALMNLDL 312
Cdd:PRK14959 241 LGLAGQELFLRLMEALAAQDCLGVANVVRELLDRGVDMGFFLRELVATWRNLFMLRQAGE----AALASLDL 308
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
5-249 4.63e-84

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 278.79  E-value: 4.63e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   5 ALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGI-T 83
Cdd:PRK07764   4 ALYRRYRPATFAEVIGQEHVTEPLSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTSTPCGECDSCVALaP 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  84 QGTNS-DVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKI 162
Cdd:PRK07764  84 GGPGSlDVTEIDAASHGGVDDARELRERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPDKV 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 163 PPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIA-FGDGTLTLQDALNVT 241
Cdd:PRK07764 164 IGTIRSRTHHYPFRLVPPEVMRGYLERICAQEGVPVEPGVLPLVIRAGGGSVRDSLSVLDQLLAgAGPEGVTYERAVALL 243

                 ....*...
gi 686156298 242 GsVHDEAL 249
Cdd:PRK07764 244 G-VTDSAL 250
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
3-286 2.29e-82

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 271.54  E-value: 2.29e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   3 YQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGI 82
Cdd:PRK14960   2 YQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKAV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  83 TQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKI 162
Cdd:PRK14960  82 NEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 163 PPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNVTG 242
Cdd:PRK14960 162 PITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEMLG 241
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 686156298 243 SVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMI 286
Cdd:PRK14960 242 LIDRTIIYDLILAVHQNQREKVSQLLLQFRYQALDVSLVLDQLI 285
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1-227 3.61e-82

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 274.03  E-value: 3.61e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK07003   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK07003  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAF 227
Cdd:PRK07003 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAY 227
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
1-260 9.26e-77

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 252.69  E-value: 9.26e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK14957   1 MSYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14957  81 AINNNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK14957 161 KIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQM 240
                        250       260
                 ....*....|....*....|
gi 686156298 241 TGSVHDEALNHLFEDIVQGD 260
Cdd:PRK14957 241 LGIIDSEEVYSIINAIIDND 260
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
2-345 4.11e-73

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 242.07  E-value: 4.11e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   2 NYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCL----NSNDGEPCNECA 77
Cdd:PRK06645   7 QYIPFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCSalitENTTIKTCEQCT 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  78 ICKGITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATT 157
Cdd:PRK06645  87 NCISFNNHNHPDIIEIDAASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATT 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 158 EPHKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFG---DGTLTL 234
Cdd:PRK06645 167 EVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASMSaksDNIISP 246
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 235 QDALNVTGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTADKDS-------DYRA- 306
Cdd:PRK06645 247 QVINQMLGLVDSSVIIEFVEYIIHRETEKAINLINKLYGSSVNLEIFIESVSDFIAYLNKVKMLPNYSlpiyesfNDRTk 326
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 686156298 307 --LMNLDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVK 345
Cdd:PRK06645 327 siLDKISLPHLSILWQIYNKGVGEIKISYNQLTETEMLVIK 367
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
1-407 1.36e-70

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 235.39  E-value: 1.36e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICK 80
Cdd:PRK14958   1 MAHQVLARKWRPRCFQEVIGQAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 GITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14958  81 EIDEGRFPDLFEVDAASRTKVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 161 KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNV 240
Cdd:PRK14958 161 KLPVTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGKVLIADVKTM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 241 TGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNKTA-----DKDSD-YRALMN-LDLE 313
Cdd:PRK14958 241 LGTIEPLLLFDILEALAAKAGDRLLGCVTRLVEQGVDFSNALADLLSLLHQIAIIQTVpealiENDSEqLRQLAKlLDRE 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 314 --MLYHMIDLINDTlvSIRFSVNQNVHFEVLLVK-LAELIKGQSQVGTNVAEPVQIAATPSSDvllqrMEQLEQELKVLK 390
Cdd:PRK14958 321 dvQLFYQIGLIGQR--DLAYSPTPQTGFEMTLLRmLAFYPSAANAIPETESKEAVVTPTPKSS-----ETSWPQLLSQLK 393
                        410
                 ....*....|....*..
gi 686156298 391 AQGVTAAPTQKTSKKPI 407
Cdd:PRK14958 394 LTGATLALAQQCSLKEL 410
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
21-349 6.10e-61

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 203.28  E-value: 6.10e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  21 QEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAiCKGITQGTNSDVIEIDAASNN- 99
Cdd:COG0470    1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCH-SRLMAAGNHPDLLELNPEEKSd 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 100 --GVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKA 177
Cdd:COG0470   80 qiGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRP 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 178 ISLDQIVERLkfvadaQALEYEEDALAFIAKASEGGMRDALSIMdQAIAFGDgtlTLQDALNVTGSVHD--EALNHLFED 255
Cdd:COG0470  160 PSEEEALAWL------REEGVDEDALEAILRLAGGDPRAAINLL-QALAGRK---ELLEDLAALLSRDRalELLDALLKA 229
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 256 IVQgdvqssfkkyhqfiaegkevnRLINDMIYFVRDTIMNKTADKDsdyralmnldlemLYHMIDLINDTLVSIRFSVNQ 335
Cdd:COG0470  230 EAL---------------------ELLDWLLKWLLDNLPLEYAGED-------------LARAYEALSEADRRLGRYAND 275
                        330
                 ....*....|....
gi 686156298 336 NVHFEVLLVKLAEL 349
Cdd:COG0470  276 RLLLEALLAKLGRL 289
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
26-212 1.66e-56

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 187.83  E-value: 1.66e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   26 KTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGITQGTNSDVIEIDAASNN-GVDEI 104
Cdd:TIGR00678   2 QQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQSiKVDQV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  105 RNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAISLDQIV 184
Cdd:TIGR00678  82 RELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEALL 161
                         170       180
                  ....*....|....*....|....*...
gi 686156298  185 ERLKfvadAQALEYEEDALAfiAKASEG 212
Cdd:TIGR00678 162 QWLI----RQGISEEAAELL--LALAGG 183
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
20-179 5.11e-56

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 185.49  E-value: 5.11e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   20 GQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGITQGTNSDVIEIDAASNN 99
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  100 -GVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAI 178
Cdd:pfam13177  81 iKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160

                  .
gi 686156298  179 S 179
Cdd:pfam13177 161 S 161
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
21-302 6.96e-43

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 156.24  E-value: 6.96e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  21 QEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGITQGTNSDVIEI--DAASN 98
Cdd:PRK08058  11 QPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDVHLVapDGQSI 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  99 NgVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAI 178
Cdd:PRK08058  91 K-KDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEFRPL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 179 SLDQIVERLkfvADAQALEYeedaLAFIAKASEGGMRDALSIMD-----QAIAfgdgtltlqdalnvtgsvhdeALNHLF 253
Cdd:PRK08058 170 PPESLIQRL---QEEGISES----LATLLAGLTNSVEEALALSEddwfaQARA---------------------LVIKLY 221
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 686156298 254 EDIVQGDVQSSFKKYHQFIAEGKEVNR--LINDMI-YFVRDTIMNKTADKDS 302
Cdd:PRK08058 222 EALHEKDLQSFVFVQEKWMPLFKEKDQqqLGLDLLlLIYRDLLYLQLGEEDR 273
rfc PRK00440
replication factor C small subunit; Reviewed
10-349 1.31e-36

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 138.47  E-value: 1.31e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  10 YRPQSFDDVVGQEHVTKTLRNAISKEKQSHaYIFSGPRGTGKTSIAKVFAKAINclnsndGEPCNEcaickgitqgtnsD 89
Cdd:PRK00440  11 YRPRTLDEIVGQEEIVERLKSYVKEKNMPH-LLFAGPPGTGKTTAALALARELY------GEDWRE-------------N 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  90 VIEIDAASNNGVDEIRN-IRDKVKYAPS-ESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTII 167
Cdd:PRK00440  71 FLELNASDERGIDVIRNkIKEFARTAPVgGAPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQ 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 168 SRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMdQAIAFGDGTLTLQDALNVTGSVHDE 247
Cdd:PRK00440 151 SRCAVFRFSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINAL-QAAAATGKEVTEEAVYKITGTARPE 229
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 248 ALNHLFEDIVQGDvqssfkkyhqFIAEGKEVNRLI-------NDMIyfvrdtimnktadkDSDYRALMNLDL--EMLYHM 318
Cdd:PRK00440 230 EIREMIELALNGD----------FTEAREKLRDLMidyglsgEDII--------------KQIHREVWSLDIpeELKVEL 285
                        330       340       350
                 ....*....|....*....|....*....|.
gi 686156298 319 IDLINDTLVSIRFSVNQNVHFEVLLVKLAEL 349
Cdd:PRK00440 286 IDAIGEADFRITEGANERIQLEALLAKLALL 316
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
15-212 2.56e-32

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 128.49  E-value: 2.56e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  15 FDDVVGQEHVTKTLRNAISKEKQ---------SHAYIFSGPRGTGKTSIAKVFAKAINClnSNDGEP-CNECAICKGITQ 84
Cdd:PRK07940   4 WDDLVGQEAVVAELRAAARAARAdvaaagsgmTHAWLFTGPPGSGRSVAARAFAAALQC--TDPDEPgCGECRACRTVLA 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  85 GTNSDV--IEIDAASNnGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKI 162
Cdd:PRK07940  82 GTHPDVrvVAPEGLSI-GVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDV 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 686156298 163 PPTIISRAQRFDFKAISLDQIVERLkfvADAQALEyEEDAlAFIAKASEG 212
Cdd:PRK07940 161 LPTIRSRCRHVALRTPSVEAVAEVL---VRRDGVD-PETA-RRAARASQG 205
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
7-243 1.34e-31

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 126.74  E-value: 1.34e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   7 YRMyRPQSFDDVVGQEHVT---KTLRNAISKEKQSHAyIFSGPRGTGKTSIAKVFAKAinclnsndgepcnecaickgit 83
Cdd:PRK13342   4 ERM-RPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSM-ILWGPPGTGKTTLARIIAGA---------------------- 59
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  84 qgTNSDVIEIDAAsNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHmlttgAFN-----ALLKTLEEppAHAIFILATTE 158
Cdd:PRK13342  60 --TDAPFEALSAV-TSGVKDLREVIEEARQRRSAGRRTILFIDEIH-----RFNkaqqdALLPHVED--GTITLIGATTE 129
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 159 -P-HKIPPTIISRAQRFDFKAISLDQIVERLKfvadaQALE--------YEEDALAFIAKASEGGMRDALSIMDQAIAFG 228
Cdd:PRK13342 130 nPsFEVNPALLSRAQVFELKPLSEEDIEQLLK-----RALEdkerglveLDDEALDALARLANGDARRALNLLELAALGV 204
                        250
                 ....*....|....*
gi 686156298 229 dGTLTLQDALNVTGS 243
Cdd:PRK13342 205 -DSITLELLEEALQK 218
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
10-261 2.81e-31

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 123.95  E-value: 2.81e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  10 YRPQSFDDVVGQEHVTKTLRNAISKEKQSHaYIFSGPRGTGKTSIAKVFAKAINclnsndGEPCNEcaickgitqgtnsD 89
Cdd:PRK12402   9 YRPALLEDILGQDEVVERLSRAVDSPNLPH-LLVQGPPGSGKTAAVRALARELY------GDPWEN-------------N 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  90 VIEIDAAS--NNGVDEIRN-----------------IRDKVK--------YAPSESKYKVYIIDEVHMLTTGAFNALLKT 142
Cdd:PRK12402  69 FTEFNVADffDQGKKYLVEdprfahflgtdkrirssKIDNFKhvlkeyasYRPLSADYKTILLDNAEALREDAQQALRRI 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 143 LEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALsIMD 222
Cdd:PRK12402 149 MEQYSRTCRFIIATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAI-LTL 227
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 686156298 223 QAIAFGDGTLTLQDALNVTGSV-HDEALNHLFEDIVQGDV 261
Cdd:PRK12402 228 QTAALAAGEITMEAAYEALGDVgTDEVIESLLDAAEAGDF 267
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
15-212 3.04e-31

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 123.47  E-value: 3.04e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  15 FDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAIncLNSNDGEPCNECAICKG------------I 82
Cdd:PRK07399   3 FANLIGQPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGL--LSQGSPSKNIRRRLEEGnhpdllwveptyQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  83 TQGT--NSDVIEIDAASNNG-----VDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEpPAHAIFILA 155
Cdd:PRK07399  81 HQGKliTASEAEEAGLKRKAppqirLEQIREIKRFLSRPPLEAPRKVVVIEDAETMNEAAANALLKTLEE-PGNGTLILI 159
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 686156298 156 TTEPHKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEG 212
Cdd:PRK07399 160 APSPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILNINFPELLALAQGSPG 216
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
14-348 1.95e-27

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 112.43  E-value: 1.95e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  14 SFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAInclnsndgepcnecaicKGITQGTNS-DVIE 92
Cdd:PRK05564   2 SFHTIIGHENIKNRIKNSIIKNRFSHAHIIVGEDGIGKSLLAKEIALKI-----------------LGKSQQREYvDIIE 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  93 IDAASNN--GVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRA 170
Cdd:PRK05564  65 FKPINKKsiGVDDIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRC 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 171 QRFDFKAISldqiverlkfvadaqaleyEEDALAFIAKASEGGMRDAlsiMDQAIAFGDGtltlqdalnVTGSV----HD 246
Cdd:PRK05564 145 QIYKLNRLS-------------------KEEIEKFISYKYNDIKEEE---KKSAIAFSDG---------IPGKVekfiED 193
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 247 EALNHL-------FEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIMNK---------TADKDSDYRAL-MN 309
Cdd:PRK05564 194 DSLKNIrnmsleiLKDIKKSNINILLKYENFLIKYKENWEEILTCILSYIRDSLLYKetgneeliiNIDKIEDIKHIsEK 273
                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 686156298 310 LDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLAE 348
Cdd:PRK05564 274 FSYKKLNKMIEIINDTRDNLSSNVNPTLVFDSMLIKMQE 312
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
7-242 5.30e-27

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 113.61  E-value: 5.30e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   7 YRMyRPQSFDDVVGQEHVT---KTLRNAIsKEKQSHAYIFSGPRGTGKTSIAKVFAKAinclnsndgepcnecaickgit 83
Cdd:COG2256   17 ERM-RPRTLDEVVGQEHLLgpgKPLRRAI-EAGRLSSMILWGPPGTGKTTLARLIANA---------------------- 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  84 qgTNSDVIEIDAASnNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHmlttgAFN-----ALLKTLEEppAHAIFILATTE 158
Cdd:COG2256   73 --TDAEFVALSAVT-SGVKDIREVIEEARERRAYGRRTILFVDEIH-----RFNkaqqdALLPHVED--GTITLIGATTE 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 159 -P-HKIPPTIISRAQRFDFKAISLDQIVERLK-FVAD------AQALEYEEDALAFIAKASEGGMRDALSIMDQAIAF-- 227
Cdd:COG2256  143 nPsFEVNSALLSRCRVFVLKPLSEEDLEQLLErALADderglgGYKLELDDEALEALARLADGDARRALNALELAVLSap 222
                        250
                 ....*....|....*..
gi 686156298 228 --GDGTLTLQDALNVTG 242
Cdd:COG2256  223 pdGVIEITLELVEEALQ 239
PLN03025 PLN03025
replication factor C subunit; Provisional
10-294 4.77e-25

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 105.97  E-value: 4.77e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  10 YRPQSFDDVVGQEHVTKTLRnAISKEKQSHAYIFSGPRGTGKTSiaKVFAKAINCLNSNDGEPcnecaickgitqgtnsd 89
Cdd:PLN03025   7 YRPTKLDDIVGNEDAVSRLQ-VIARDGNMPNLILSGPPGTGKTT--SILALAHELLGPNYKEA----------------- 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  90 VIEIDAASNNGVDEIRN-----IRDKVKYAPSesKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPP 164
Cdd:PLN03025  67 VLELNASDDRGIDVVRNkikmfAQKKVTLPPG--RHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIE 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 165 TIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMdQAIAFGDGTLTLQDALNVTGSV 244
Cdd:PLN03025 145 PIQSRCAIVRFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNL-QATHSGFGFVNQENVFKVCDQP 223
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 686156298 245 HDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVRDTIM 294
Cdd:PLN03025 224 HPLHVKNIVRNCLKGKFDDACDGLKQLYDLGYSPTDIITTLFRVVKNYDM 273
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
39-223 7.46e-25

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 105.56  E-value: 7.46e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  39 HAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGITQGTNSD--VIEIDAASNN-GVDEIRNIRDKVKYAP 115
Cdd:PRK05707  23 HAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDnfVLEPEEADKTiKVDQVRELVSFVVQTA 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 116 SESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAISLDQIVERLkfvadAQA 195
Cdd:PRK05707 103 QLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEESLQWL-----QQA 177
                        170       180
                 ....*....|....*....|....*....
gi 686156298 196 L-EYEEDALAFIAKASEGGMRDALSIMDQ 223
Cdd:PRK05707 178 LpESDERERIELLTLAGGSPLRALQLHEQ 206
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
178-242 3.06e-24

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 95.65  E-value: 3.06e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 686156298 178 ISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDGTLTLQDALNVTG 242
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
34-218 4.07e-23

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 100.61  E-value: 4.07e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  34 KEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSN-DGEPCNECAICKGITQGTNSD-------VIEIDAASNNG----- 100
Cdd:PRK06964  17 RARLPHALLLHGQAGIGKLDFAQHLAQGLLCETPQpDGEPCGTCAACNWFAQGNHPDyrivrpeALAAEAPGAADeakea 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 101 -----------------VDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIP 163
Cdd:PRK06964  97 dadeggkktkapskeikIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEEPPPGTVFLLVSARIDRLL 176
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 686156298 164 PTIISRAQRFDFKAISLDQIVERLKF--VADAQALEYEEDA--LAFIAkASEGGMRDAL 218
Cdd:PRK06964 177 PTILSRCRQFPMTVPAPEAAAAWLAAqgVADADALLAEAGGapLAALA-LASDENRPLR 234
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
35-234 2.11e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 98.40  E-value: 2.11e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  35 EKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDG-EPCNECAICKGITQGTNSDVIEIDAASN---NG-------VDE 103
Cdd:PRK08699  18 ERRPNAWLFAGKKGIGKTAFARFAAQALLCETPAPGhKPCGECMSCHLFGQGSHPDFYEITPLSDepeNGrkllqikIDA 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 104 IRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAISLDQI 183
Cdd:PRK08699  98 VREIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVLPAPSHEEA 177
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 184 VERLKF--VADAqaleyeEDALAFIAKA----SEGGMR-------------DALSIMDQAIAFGDGTLTL 234
Cdd:PRK08699 178 LAYLRErgVAEP------EERLAFHSGAplfdEEPELRalriklldilaepRLLKILDYAALFDKEKLPL 241
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
12-274 1.42e-21

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 96.26  E-value: 1.42e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  12 PQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAkvFAKAINCLNSND--------GEPCNECAICKGIT 83
Cdd:PRK09112  19 PSENTRLFGHEEAEAFLAQAYREGKLHHALLFEGPEGIGKATLA--FHLANHILSHPDpaeapetlADPDPASPVWRQIA 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  84 QGTNSDVIEID---------AASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFIL 154
Cdd:PRK09112  97 QGAHPNLLHITrpfdektgkFKTAITVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFIL 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 155 ATTEPHKIPPTIISRAQRFDFKAISLDQIVERLKFVADAQALeyEEDALAFIAKASEGGMRDALSIMDQaiafgdGTLTL 234
Cdd:PRK09112 177 ISHSSGRLLPTIRSRCQPISLKPLDDDELKKALSHLGSSQGS--DGEITEALLQRSKGSVRKALLLLNY------GGLEI 248
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 686156298 235 QDALN--VTGSVHDEALNHLFEDIVQGdvQSSFKKYHQFIAE 274
Cdd:PRK09112 249 IATIDqlLAGSGPDARKAHKLADALSG--RESEVQFDFFRDH 288
PRK04195 PRK04195
replication factor C large subunit; Provisional
10-242 1.74e-21

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 97.68  E-value: 1.74e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  10 YRPQSFDDVVGQEHVTKTLR---NAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINclnsndgepcnecaickgitqgt 86
Cdd:PRK04195   8 YRPKTLSDVVGNEKAKEQLRewiESWLKGKPKKALLLYGPPGVGKTSLAHALANDYG----------------------- 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  87 nSDVIEIDAASNNGVDEIRNIrdkVKYAPSES-----KYKVYIIDEVHMLT----TGAFNALLKTLEEPpAHAIfILATT 157
Cdd:PRK04195  65 -WEVIELNASDQRTADVIERV---AGEAATSGslfgaRRKLILLDEVDGIHgnedRGGARAILELIKKA-KQPI-ILTAN 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 158 EPHKIPP-TIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDAlsIMD-QAIAFGDGTLTLQ 235
Cdd:PRK04195 139 DPYDPSLrELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSA--INDlQAIAEGYGKLTLE 216

                 ....*..
gi 686156298 236 DALNVTG 242
Cdd:PRK04195 217 DVKTLGR 223
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
31-171 6.98e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 90.95  E-value: 6.98e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  31 AISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGITQGTNSDVIEIDAASNN--GVDEIRNIR 108
Cdd:PRK06871  17 AFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHILEPIDNKdiGVDQVREIN 96
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 686156298 109 DKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQ 171
Cdd:PRK06871  97 EKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQ 159
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
17-238 2.95e-19

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 89.70  E-value: 2.95e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  17 DVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAI--NCLNSNDGEPCN--------ECAICKGITQGT 86
Cdd:PRK07471  20 ALFGHAAAEAALLDAYRSGRLHHAWLIGGPQGIGKATLAYRMARFLlaTPPPGGDGAVPPptslaidpDHPVARRIAAGA 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  87 NSDVIEIDAASNNG---------VDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATT 157
Cdd:PRK07471 100 HGGLLTLERSWNEKgkrlrtvitVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSH 179
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 158 EPHKIPPTIISRAQRFDFKAISLDQIVErlkfVADAQALEYEEDALAFIAKASEGGMRDALSIMDqaiafGDGtLTLQDA 237
Cdd:PRK07471 180 APARLLPTIRSRCRKLRLRPLAPEDVID----ALAAAGPDLPDDPRAALAALAEGSVGRALRLAG-----GDG-LALYRR 249

                 .
gi 686156298 238 L 238
Cdd:PRK07471 250 L 250
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
32-176 1.00e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 83.91  E-value: 1.00e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  32 ISKEKQSHAYIFSGprGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGITQGTNSDVIEIdaASNNGVDEIRNIRDKV 111
Cdd:PRK07276  18 LEQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDVTVI--EPQGQVIKTDTIRELV 93
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 686156298 112 K-YAPS--ESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFK 176
Cdd:PRK07276  94 KnFSQSgyEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHFP 161
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
28-188 4.43e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 82.54  E-value: 4.43e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  28 LRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSNDgEPCNECAICKGITQGTNSD--VIEIDAASNN-GVDEI 104
Cdd:PRK06090  15 WKAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQNYQS-EACGFCHSCELMQSGNHPDlhVIKPEKEGKSiTVEQI 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 105 RNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAISLDQIV 184
Cdd:PRK06090  94 RQCNRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTPPSTAQAM 173

                 ....
gi 686156298 185 ERLK 188
Cdd:PRK06090 174 QWLK 177
44 PHA02544
clamp loader, small subunit; Provisional
1-347 5.52e-17

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 81.96  E-value: 5.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   1 MNYQALYRMYRPQSFDDVVGQEHVTKTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFakainclnsndgepCNEcaick 80
Cdd:PHA02544   6 PNEFMWEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPSPGTGKTTVAKAL--------------CNE----- 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  81 gitqgTNSDVIEIDAASNNgVDEIRNirDKVKYAPSES---KYKVYIIDEVHMLTTGAFNALLKTL-EEPPAHAIFILAT 156
Cdd:PHA02544  67 -----VGAEVLFVNGSDCR-IDFVRN--RLTRFASTVSltgGGKVIIIDEFDRLGLADAQRHLRSFmEAYSKNCSFIITA 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 157 TEPHKIPPTIISRAQRFDF------KAISL-DQIVERLKFVADAQALEYEEDALAFIAKASeggmrdalsimdqaiaFGD 229
Cdd:PHA02544 139 NNKNGIIEPLRSRCRVIDFgvptkeEQIEMmKQMIVRCKGILEAEGVEVDMKVLAALVKKN----------------FPD 202
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 230 --GTLTLQDALNVTGSVHDEALNHLFEDIVqGDVQSSFKkyhqfiaeGKEVNRlindmiyfVRDTIMNKTADKDSDYRAL 307
Cdd:PHA02544 203 frRTINELQRYASTGKIDAGILSEVTNSDI-DDVVEALK--------AKDFKA--------VRALAPNYANDYASFVGKL 265
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 686156298 308 MN-----LDLEMLYHMIDLINDTLVSIRFSVNQNVHFEVLLVKLA 347
Cdd:PHA02544 266 YDelypqVTPPSIIRLIEIIGENNQYHGFAADQEIHLLYLLTQLM 310
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
105-170 2.20e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 79.84  E-value: 2.20e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 686156298 105 RNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRA 170
Cdd:PRK05917  81 RAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRS 146
PRK04132 PRK04132
replication factor C small subunit; Provisional
91-229 3.10e-14

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 76.03  E-value: 3.10e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  91 IEIDAASNNGVDEIRN-IRDKVKYAP-SESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIIS 168
Cdd:PRK04132 600 LELNASDERGINVIREkVKEFARTKPiGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPIQS 679
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 686156298 169 RAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGD 229
Cdd:PRK04132 680 RCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQAAAALDD 740
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
26-224 3.45e-14

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 73.22  E-value: 3.45e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  26 KTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFakaINCLNSNDGEPCNECAICKGITQgtnSDVIEIDAASNNGVDEIR 105
Cdd:PRK07132   6 KFLDNSATQNKISHSFLLKSNYNEDIDEKILYF---LNKFNNLQITNLNEQELPANIIL---FDIFDKDLSKSEFLSAIN 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 106 NIrdkVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAISLDQIVE 185
Cdd:PRK07132  80 KL---YFSSFVQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKILA 156
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 686156298 186 rlKFVADAQALEYE----------EDALAFIAKASEGGMRDALSIMDQA 224
Cdd:PRK07132 157 --KLLSKNKEKEYNwfyayifsnfEQAEKYINKESENLLKKFEEALNKS 203
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
31-176 1.18e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 71.91  E-value: 1.18e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  31 AISKEKQSHAYIFSGPRGTGKTSIAkvFAKAINCLNSNDgEPCNECAICKGITQGTNSDVIEIDAASNNGVD-------- 102
Cdd:PRK08769  19 ALDAGRLGHGLLICGPEGLGKRAVA--LALAEHVLASGP-DPAAAQRTRQLIAAGTHPDLQLVSFIPNRTGDklrteivi 95
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 686156298 103 -EIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFK 176
Cdd:PRK08769  96 eQVREISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQRLEFK 170
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
19-169 1.64e-13

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 68.33  E-value: 1.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  19 VGQEHVTKTLRNAISKEKQSHaYIFSGPRGTGKTSIAKVFAKAINclnsndgepcnecaickgitqGTNSDVIEIDAASN 98
Cdd:cd00009    1 VGQEEAIEALREALELPPPKN-LLLYGPPGTGKTTLARAIANELF---------------------RPGAPFLYLNASDL 58
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  99 NGVDEIRNIRDKVKY-----APSESKYKVYIIDEVHMLTTGAFNALLKTLEE------PPAHAIFILATT--EPHKIPPT 165
Cdd:cd00009   59 LEGLVVAELFGHFLVrllfeLAEKAKPGVLFIDEIDSLSRGAQNALLRVLETlndlriDRENVRVIGATNrpLLGDLDRA 138

                 ....
gi 686156298 166 IISR 169
Cdd:cd00009  139 LYDR 142
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
39-169 2.06e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 71.64  E-value: 2.06e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  39 HAYIFSGPRGTGKTSIAKVFAKAINCLNSNDGEPCNECAICKGITQGTNSD--VIEIDAASNN-GVDEIRNIRDKVKYAP 115
Cdd:PRK07993  25 HALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDyyTLTPEKGKSSlGVDAVREVTEKLYEHA 104
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 686156298 116 SESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISR 169
Cdd:PRK07993 105 RLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSR 158
PRK13341 PRK13341
AAA family ATPase;
8-225 5.17e-13

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 72.01  E-value: 5.17e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   8 RMyRPQSFDDVVGQEHVT---KTLRNAISKEKQSHAyIFSGPRGTGKTSIAKVFAKAinclnsndgepcnecaickgitq 84
Cdd:PRK13341  21 RL-RPRTLEEFVGQDHILgegRLLRRAIKADRVGSL-ILYGPPGVGKTTLARIIANH----------------------- 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  85 gTNSDVIEIDAASNnGVDEIRNirdKVKYAPSESKY----KVYIIDEVHMLTTGAFNALLKTLEEppAHAIFILATTE-P 159
Cdd:PRK13341  76 -TRAHFSSLNAVLA-GVKDLRA---EVDRAKERLERhgkrTILFIDEVHRFNKAQQDALLPWVEN--GTITLIGATTEnP 148
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 686156298 160 H-KIPPTIISRAQRFDFKAIS---LDQIVERLkfVADAQ------ALEYEEDALAFIAKASEGGMRDALSIMDQAI 225
Cdd:PRK13341 149 YfEVNKALVSRSRLFRLKSLSdedLHQLLKRA--LQDKErgygdrKVDLEPEAEKHLVDVANGDARSLLNALELAV 222
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
41-173 4.28e-12

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 63.38  E-value: 4.28e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   41 YIFSGPRGTGKTSIAKVFAKAinclnsndgepcnecaickgitqgTNSDVIEIDAAS--NNGVDE-IRNIRDKVKYAPSE 117
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKE------------------------LGAPFIEISGSElvSKYVGEsEKRLRELFEAAKKL 56
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  118 SKyKVYIIDEVHMLTT-----------GAFNALLKTLEEPPAHA---IFILATTEPHKIPPTIISRAQRF 173
Cdd:pfam00004  57 AP-CVIFIDEIDALAGsrgsggdsesrRVVNQLLTELDGFTSSNskvIVIAATNRPDKLDPALLGRFDRI 125
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
8-236 9.53e-12

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 66.86  E-value: 9.53e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298   8 RMYRPQSFDDVVGQEHVTKTLRNAIS------------KEKQSHAYIFSGPRGTGKTSIAKVFAKAINclnsndgepcne 75
Cdd:COG0464  149 LELREAILDDLGGLEEVKEELRELVAlplkrpelreeyGLPPPRGLLLYGPPGTGKTLLARALAGELG------------ 216
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  76 caickgitqgtnSDVIEIDAAsnngvdEI---------RNIRDKVKYAPSESKYkVYIIDEVHMLTTG-----------A 135
Cdd:COG0464  217 ------------LPLIEVDLS------DLvskyvgeteKNLREVFDKARGLAPC-VLFIDEADALAGKrgevgdgvgrrV 277
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 136 FNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQR-FDFKAISLDQIVERLKFVADAQALEYEEDaLAFIAKASEGG- 213
Cdd:COG0464  278 VNTLLTEMEELRSDVVVIAATNRPDLLDPALLRRFDEiIFFPLPDAEERLEIFRIHLRKRPLDEDVD-LEELAEATEGLs 356
                        250       260
                 ....*....|....*....|....*..
gi 686156298 214 ---MRDAL-SIMDQAIAFGDGTLTLQD 236
Cdd:COG0464  357 gadIRNVVrRAALQALRLGREPVTTED 383
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
58-201 3.64e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 63.70  E-value: 3.64e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  58 FAKAINCLNSNdgEPCNECAICKGITQGTNSDVIEI-DAASNNGVDEIRNIRDKVKYaPSESKY--KVYIIDEVHMLTTG 134
Cdd:PRK05818  27 YLTSIVCTKAN--GFCKTCESCLKILNGKYNDFYLIfDQKNPIKKEDALSIINKLNR-PSVESNgkKIYIIYGIEKLNKQ 103
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 686156298 135 AFNALLKTLEEPPAHAIFILATTEPHKIPPTIISR---------AQRFDFKAISLDQIVERLK---FVADAQaLEYEED 201
Cdd:PRK05818 104 SANSLLKLIEEPPKNTYGIFTTRNENNILNTILSRcvqyvvlskEKKVPFKVESNDRYFQYILlsfYSVDEQ-LQAYNN 181
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
11-252 3.02e-10

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 61.69  E-value: 3.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  11 RPQSFDDVVGQEHVTKTLRNAIS-----KEKQSHAyIFSGPRGTGKTSIAKVFAkaiNCLNSNdgepcnecaiCKgITQG 85
Cdd:PRK00080  20 RPKSLDEFIGQEKVKENLKIFIEaakkrGEALDHV-LLYGPPGLGKTTLANIIA---NEMGVN----------IR-ITSG 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  86 TnsdVIE--ID-AASNNGVDEirniRDkvkyapseskykVYIIDEVHmlttgafnALLKTLEE----------------- 145
Cdd:PRK00080  85 P---ALEkpGDlAAILTNLEE----GD------------VLFIDEIH--------RLSPVVEEilypamedfrldimigk 137
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 146 -PPAHAI------FIL--ATTEPHKIPPTIISR---AQRFDF-KAISLDQIVERLkfvADAQALEYEEDALAFIAKASEG 212
Cdd:PRK00080 138 gPAARSIrldlppFTLigATTRAGLLTSPLRDRfgiVQRLEFyTVEELEKIVKRS---ARILGVEIDEEGALEIARRSRG 214
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 686156298 213 GMRDALS----IMDQAIAFGDGTLTLQDAlnvtgsvhDEALNHL 252
Cdd:PRK00080 215 TPRIANRllrrVRDFAQVKGDGVITKEIA--------DKALDML 250
HolA COG1466
DNA polymerase III, delta subunit [Replication, recombination and repair];
118-290 6.07e-10

DNA polymerase III, delta subunit [Replication, recombination and repair];


Pssm-ID: 441075 [Multi-domain]  Cd Length: 305  Bit Score: 60.65  E-value: 6.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 118 SKYKVYIIDEVHMLTTG--AFNALLKTLEEPPAHAIFILATTEP---HKIPPTIISRAQRFDFKAISLDQIVERLKFVAD 192
Cdd:COG1466   61 GERRLVIVRNAEFLKKPgeGLEALEAYLANPPPDTVLVLTAGKLdkrKKLFKALEKAGVVVECYPLKERELPAWIRQRLK 140
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 193 AQALEYEEDALAFIAKASEGGMRDALSIMDQ--AIAFGDGTLTLQDALNVTGSVHDEALNHLFEDIVQGDVQSSFKKYHQ 270
Cdd:COG1466  141 AAGLRIDPDAAQLLAERVGGDLLALAQELEKlaLYAGDGGTITLEDVEALVGDSAEFNVFDLADALLAGDAARALRILRR 220
                        170       180
                 ....*....|....*....|
gi 686156298 271 FIAEGKEVNRLINDMIYFVR 290
Cdd:COG1466  221 LLAEGEEPVLILAALARQFR 240
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
15-212 2.13e-09

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 58.36  E-value: 2.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  15 FDDVVGQEHVTKTLRNAISKEKQ-----------SHAYIFSGPRGTGKTSIAKVFAKAinclnsndgepcnecaickgit 83
Cdd:COG1223    1 LDDVVGQEEAKKKLKLIIKELRRrenlrkfglwpPRKILFYGPPGTGKTMLAEALAGE---------------------- 58
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  84 qgTNSDVIEI-----------DAASNngvdeIRNIRDKVKYAPSeskykVYIIDEVHMLT--------TG----AFNALL 140
Cdd:COG1223   59 --LKLPLLTVrldsligsylgETARN-----LRKLFDFARRAPC-----VIFFDEFDAIAkdrgdqndVGevkrVVNALL 126
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 686156298 141 KTLEEPPAHAIFILATTEPHKIPPTIISraqRFD----FKAISLDQIVERLKFVADAQALEYEEDALAfIAKASEG 212
Cdd:COG1223  127 QELDGLPSGSVVIAATNHPELLDSALWR---RFDevieFPLPDKEERKEILELNLKKFPLPFELDLKK-LAKKLEG 198
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
178-241 8.11e-09

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 52.15  E-value: 8.11e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 686156298 178 ISLDQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMdQAIAFGDGTLTLQDALNVT 241
Cdd:cd18140    1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDL-QAAAAGGGVITEEDVYEVA 63
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
26-176 2.86e-07

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 50.36  E-value: 2.86e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  26 KTLRNAISKEKQSHAYIFSGPRGTGKTSIAKVFAkainclnsndGEpcnecaickgitqgTNSDVIEIDAASNNGV---D 102
Cdd:cd19481   14 RGSRLRRYGLGLPKGILLYGPPGTGKTLLAKALA----------GE--------------LGLPLIVVKLSSLLSKyvgE 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 103 EIRNIRDKVKYApSESKYKVYIIDEVHML------------TTGAFNALLKTLEEPPA--HAIFILATTEPHKIPPTIIs 168
Cdd:cd19481   70 SEKNLRKIFERA-RRLAPCILFIDEIDAIgrkrdssgesgeLRRVLNQLLTELDGVNSrsKVLVIAATNRPDLLDPALL- 147

                 ....*...
gi 686156298 169 RAQRFDFK 176
Cdd:cd19481  148 RPGRFDEV 155
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
41-176 6.17e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 49.29  E-value: 6.17e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298    41 YIFSGPRGTGKTSIAKVFAKAINCLNSN----DGEPcnecaICKGITQGTNSDVIEIDAASNNGVDEIRNIRDKVKYaps 116
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPGGGviyiDGED-----ILEEVLDQLLLIIVGGKKASGSGELRLRLALALARK--- 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 686156298   117 eSKYKVYIIDEVHMLTTGAFNALL--------KTLEEPPAHAIFILATTEPHKIPPTIISRaqRFDFK 176
Cdd:smart00382  77 -LKPDVLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDLGPALLRR--RFDRR 141
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
116-176 1.26e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 49.26  E-value: 1.26e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 686156298 116 SESKYKVYIIdEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFK 176
Cdd:PRK08485  52 AESEEKIIVI-AAPSYGIEAQNALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLIIEKRK 111
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
11-60 1.42e-06

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 48.27  E-value: 1.42e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 686156298   11 RPQSFDDVVGQEHVTKTLRNAISKEKQ-----SHAyIFSGPRGTGKTSIAKVFAK 60
Cdd:pfam05496   2 RPRTLDEYIGQEKVKENLKIFIEAAKQrgealDHV-LLYGPPGLGKTTLANIIAN 55
PRK04132 PRK04132
replication factor C small subunit; Provisional
10-59 3.41e-06

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 50.22  E-value: 3.41e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 686156298  10 YRPQSFDDVVGQEHVTKTLRNAISKEKQSHaYIFSGPRGTGK--TSIAKVFA 59
Cdd:PRK04132  13 YRPQRLDDIVGQEHIVKRLKHYVKTGSMPH-LLFAGPPGVGKclTGDTKVIA 63
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
96-198 4.97e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 48.30  E-value: 4.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  96 ASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDF 175
Cdd:PRK06581  66 AKNISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRSRCFKINV 145
                         90       100
                 ....*....|....*....|....*..
gi 686156298 176 KAISL----DQIVERLKFVADAQALEY 198
Cdd:PRK06581 146 RSSILhaynELYSQFIQPIADNKTLDF 172
RuvB COG2255
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ...
11-252 5.43e-06

Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];


Pssm-ID: 441856 [Multi-domain]  Cd Length: 337  Bit Score: 48.54  E-value: 5.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  11 RPQSFDDVVGQEHVTKTLRNAISKEKQ-----SHAyIFSGPRGTGKTSIAKVFAkaiNCLNSNdgepcnecaiCKgITQG 85
Cdd:COG2255   23 RPKRLDEYIGQEKVKENLKIFIEAAKKrgealDHV-LLYGPPGLGKTTLAHIIA---NEMGVN----------IR-ITSG 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  86 TnsdVIEI--D-AA--SNngVDEirniRDkvkyapseskykVYIIDEVHMLTtgafnallKTLEE--------------- 145
Cdd:COG2255   88 P---AIEKpgDlAAilTN--LEE----GD------------VLFIDEIHRLS--------RVVEEilypamedfrldivi 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 146 ---PPAHAI------FIL--ATTEPHKIPPTIISR---AQRFDF-KAISLDQIVERlkfVADAQALEYEEDALAFIAKAS 210
Cdd:COG2255  139 gkgPAARSIrldlppFTLvgATTRAGLLTSPLRDRfgiVLRLEFyTVEELAEIVKR---SARILGVEIDEEGALEIARRS 215
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 686156298 211 EGGMRDALSIM----DQAIAFGDGTLTLQDAlnvtgsvhDEALNHL 252
Cdd:COG2255  216 RGTPRIANRLLrrvrDFAQVKGDGVITLEIA--------DAALELL 253
HLD_clamp cd18133
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ...
181-230 1.24e-05

helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.


Pssm-ID: 350838 [Multi-domain]  Cd Length: 65  Bit Score: 43.23  E-value: 1.24e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 686156298 181 DQIVERLKFVADAQALEYEEDALAFIAKASEGGMRDALSIMDQAIAFGDG 230
Cdd:cd18133    4 EQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGDD 53
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
14-174 4.25e-04

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 42.69  E-value: 4.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  14 SFDDVVGQEHVTKTLRNAISKE-KQSHAY-----------IFSGPRGTGKTSIAKVFAkainclnsndgepcNEcaickg 81
Cdd:COG1222   76 TFDDIGGLDEQIEEIREAVELPlKNPELFrkygieppkgvLLYGPPGTGKTLLAKAVA--------------GE------ 135
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  82 itqgTNSDVIEIDAasnngvDEI---------RNIRDKVKYApSESKYKVYIIDEV--------HMLTTGA----FNALL 140
Cdd:COG1222  136 ----LGAPFIRVRG------SELvskyigegaRNVREVFELA-REKAPSIIFIDEIdaiaarrtDDGTSGEvqrtVNQLL 204
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 686156298 141 KTLEE-PPAHAIFILATTE-PHKIPPTIIsRAQRFD 174
Cdd:COG1222  205 AELDGfESRGDVLIIAATNrPDLLDPALL-RPGRFD 239
TIP49 COG1224
DNA helicase TIP49, TBP-interacting protein [Transcription];
102-224 4.26e-04

DNA helicase TIP49, TBP-interacting protein [Transcription];


Pssm-ID: 440837 [Multi-domain]  Cd Length: 452  Bit Score: 43.04  E-value: 4.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298 102 DEIRNIRDK-VKYAPSESKYK----VYIIDEVHMLTTGAFNALLKTLEEPPAhAIFILAT---------TE---PHKIPP 164
Cdd:COG1224  270 SEVRKQVDElVKKWIEEGKAElvpgVLFIDDAHMLDIEAFSFLTRAMESELA-PIIILATnrgitkirgTDiesPHGIPL 348
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 686156298 165 TIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAK-ASEGGMRDALSIMDQA 224
Cdd:COG1224  349 DLLDRLLIIPTRPYTEDEIREIIKIRAEEEDIELSDDALEELTKiGVERSLRYAVQLLEPA 409
holA TIGR01128
DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) ...
137-347 8.24e-04

DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) subunits are distinct proteins encoded by separate genes. The delta prime subunit (holB) exhibits sequence homology to the tau and gamma subunits (dnaX), but the delta subunit (holA) does not demonstrate this same homology with dnaX. The delta, delta prime, gamma, chi and psi subunits form the gamma complex subassembly of DNA polymerase III holoenzyme, which couples ATP to assemble the ring-shaped beta subunit around DNA forming a DNA sliding clamp. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273455 [Multi-domain]  Cd Length: 302  Bit Score: 41.48  E-value: 8.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  137 NALLKTLEEPPAHAIFILATTEP---HKI--PPTIISRAQRFDFKAISLDQIVERLKFVADAQALEYEEDALAFIAKASE 211
Cdd:TIGR01128  65 KALEEYLANPPPDTLLLIEAPKLdkrKKLtkWLKALKNAEIVECKTPKEQELPRWIQARLKKLGLRIDPDAVQLLAELVE 144
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686156298  212 GGMRDALSIMDQAIAF-GDGTLTLQDALNVTGSVHDEALNHLFEDIVQGDVQSSFKKYHQFIAEGKEVNRLINDMIYFVR 290
Cdd:TIGR01128 145 GNLLAIAQELEKLALYaPDGKITLEDVEEAVSDSARFNVFDLTDALLEGKAARALRILKGLLGEGEEPLILLALLQRQLR 224
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 686156298  291 ---------DTIMNKTADKDS----DYR------ALMNLDLEMLYHMIDLINDTLVSIRFSVNQNVHFEV--LLVKLA 347
Cdd:TIGR01128 225 lllqlkrlaQQGGPLAQLASKlgiwPYRrklalkALRRLSLAKLEQALQELAEADLQLKGTGGGDPWLALerLLLKLA 302
TIP49 pfam06068
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and ...
122-170 2.91e-03

TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases.


Pssm-ID: 399217 [Multi-domain]  Cd Length: 347  Bit Score: 39.99  E-value: 2.91e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 686156298  122 VYIIDEVHMLTTGAFNALLKTLEEPPAhAIFILATT------------EPHKIPPTIISRA 170
Cdd:pfam06068 277 VLFIDEVHMLDIECFSFLNRALESDLA-PIVILATNrgictirgtdiiSPHGIPLDLLDRL 336
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
18-63 5.64e-03

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 37.87  E-value: 5.64e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 686156298   18 VVGQEHVTKTLRNAISK--EKQSHAYIFSGPRGTGKTSIAKVFAKAIN 63
Cdd:pfam13191   2 LVGREEELEQLLDALDRvrSGRPPSVLLTGEAGTGKTTLLRELLRALE 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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