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Conserved domains on  [gi|691141162|ref|WP_032054389|]
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MULTISPECIES: phosphatase PAP2 family protein [Acinetobacter]

Protein Classification

PgpB family protein( domain architecture ID 11430553)

PgpB family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 10-175 8.83e-22

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


:

Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 87.40  E-value: 8.83e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  10 ILDLDLRGCLYLNNFSHSQRVALFFKIISRVGDGPFWYLMLAIVWGMQGITYSLQIIYLLLGGSVGTAIYKFLKHKTTRP 89
Cdd:COG0671   20 LALALLALLLLLALLLLLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALLLLLLLLLLLLLKYLFGRP 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  90 RPYQVHQVIVLGERPlDHFSFPSGHTLHAVMVTIVLGYIQP--VLLAAMFPFMVLVALSRMVLGLHYPSDVIVGALIGAA 167
Cdd:COG0671  100 RPFVVPDLELLLGTA-GGYSFPSGHAAAAFALALVLALLLPrrWLAALLLALALLVGLSRVYLGVHYPSDVLAGALLGLA 178


                 ....*...
gi 691141162 168 VAAMIIFV 175
Cdd:COG0671  179 IALLLLAL 186
 
Name Accession Description Interval E-value
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 10-175 8.83e-22

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 87.40  E-value: 8.83e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  10 ILDLDLRGCLYLNNFSHSQRVALFFKIISRVGDGPFWYLMLAIVWGMQGITYSLQIIYLLLGGSVGTAIYKFLKHKTTRP 89
Cdd:COG0671   20 LALALLALLLLLALLLLLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALLLLLLLLLLLLLKYLFGRP 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  90 RPYQVHQVIVLGERPlDHFSFPSGHTLHAVMVTIVLGYIQP--VLLAAMFPFMVLVALSRMVLGLHYPSDVIVGALIGAA 167
Cdd:COG0671  100 RPFVVPDLELLLGTA-GGYSFPSGHAAAAFALALVLALLLPrrWLAALLLALALLVGLSRVYLGVHYPSDVLAGALLGLA 178


                 ....*...
gi 691141162 168 VAAMIIFV 175
Cdd:COG0671  179 IALLLLAL 186
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 65-173 6.79e-19

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 77.89  E-value: 6.79e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  65 IIYLLLGGSVGTAIYKFLKHKTTRPRPYQVHQVIVLGERPL---DHFSFPSGHTLHAVMVTIVLGYI------QPVLLAA 135
Cdd:cd01610    5 ALLLLLALLAGLLLTGVLKYLFGRPRPYFLLRCGPDGDPLLlteGGYSFPSGHAAFAFALALFLALLlprrllRLLLGLL 84

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 691141162 136 MFPFMVLVALSRMVLGLHYPSDVIVGALIGAAVAAMII 173
Cdd:cd01610   85 LLLLALLVGLSRVYLGVHYPSDVLAGALLGILVALLVL 122
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 67-170 4.30e-16

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 70.53  E-value: 4.30e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162   67 YLLLGGSVGTAIYKFLKHKTTRPRPYQVHQVIVLGERPLDHF----SFPSGHTLHAVMVTIVLGYIQP--------VLLA 134
Cdd:pfam01569   1 ILLLALALAGLLSSVLKDYFGRPRPFFLLLEGGLVPAPSTLPglgySFPSGHSATAFALALLLALLLRrlrkivrvLLAL 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 691141162  135 AMFPFMVLVALSRMVLGLHYPSDVIVGALIGAAVAA 170
Cdd:pfam01569  81 LLLVLALLVGLSRLYLGVHFPSDVLAGALIGILLAL 116
acidPPc smart00014
Acid phosphatase homologues;
81-170 6.76e-12

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 59.28  E-value: 6.76e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162    81 FLKHKTTRPRPYQV--HQVIVLGERPLDH---FSFPSGHTLHAVMVTIVLGYIQP------VLLAAMFPFMVLVALSRMV 149
Cdd:smart00014  13 VIKNYFGRPRPFFLsiGDACCTPNFLLTLeagYSFPSGHTAFAFAFALFLLLYLParagrkLLIFLLLLLALVVGFSRVY 92

                           90       100
                   ....*....|....*....|.
gi 691141162   150 LGLHYPSDVIVGALIGAAVAA 170
Cdd:smart00014  93 LGAHWPSDVLAGSLLGILIAA 113
PRK10699 PRK10699
phosphatidylglycerophosphatase B; Provisional
 108-176 2.33e-06

phosphatidylglycerophosphatase B; Provisional


Pssm-ID: 182658  Cd Length: 244  Bit Score: 46.18  E-value: 2.33e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 691141162 108 FSFPSGHTLHAV-MVTIVLGYIQP----VLLAAMFPFMVLVALSRMVLGLHYPSDVIVGALIGAAVAAMIIFVA 176
Cdd:PRK10699 157 FAFPSGHTMFAAsWALLAVGLLWPrrryKTVALLMLWATGVMGSRLLLGMHWPRDLVVATLISWLLVTVATWLA 230
 
Name Accession Description Interval E-value
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 10-175 8.83e-22

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 87.40  E-value: 8.83e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  10 ILDLDLRGCLYLNNFSHSQRVALFFKIISRVGDGPFWYLMLAIVWGMQGITYSLQIIYLLLGGSVGTAIYKFLKHKTTRP 89
Cdd:COG0671   20 LALALLALLLLLALLLLLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALLLLLLLLLLLLLKYLFGRP 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  90 RPYQVHQVIVLGERPlDHFSFPSGHTLHAVMVTIVLGYIQP--VLLAAMFPFMVLVALSRMVLGLHYPSDVIVGALIGAA 167
Cdd:COG0671  100 RPFVVPDLELLLGTA-GGYSFPSGHAAAAFALALVLALLLPrrWLAALLLALALLVGLSRVYLGVHYPSDVLAGALLGLA 178


                 ....*...
gi 691141162 168 VAAMIIFV 175
Cdd:COG0671  179 IALLLLAL 186
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 65-173 6.79e-19

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 77.89  E-value: 6.79e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  65 IIYLLLGGSVGTAIYKFLKHKTTRPRPYQVHQVIVLGERPL---DHFSFPSGHTLHAVMVTIVLGYI------QPVLLAA 135
Cdd:cd01610    5 ALLLLLALLAGLLLTGVLKYLFGRPRPYFLLRCGPDGDPLLlteGGYSFPSGHAAFAFALALFLALLlprrllRLLLGLL 84

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 691141162 136 MFPFMVLVALSRMVLGLHYPSDVIVGALIGAAVAAMII 173
Cdd:cd01610   85 LLLLALLVGLSRVYLGVHYPSDVLAGALLGILVALLVL 122
PAP2_like_1 cd03380
PAP2_like_1 proteins, a sub-family of PAP2, containing bacterial acid phosphatase, vanadium ...
 88-172 4.00e-17

PAP2_like_1 proteins, a sub-family of PAP2, containing bacterial acid phosphatase, vanadium chloroperoxidases and vanadium bromoperoxidases.


Pssm-ID: 239475  Cd Length: 209  Bit Score: 75.55  E-value: 4.00e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  88 RPRPYQVH----QVIVLGERPL-DHFSFPSGHTLHAVMVTIVLGYIQPVLLAAMFPFMVLVALSRMVLGLHYPSDVIVGA 162
Cdd:cd03380  118 RPRPFVAIrlqwLPICTPEEGTpKHPSYPSGHATFGGAAALVLAELFPERAAELLARAAEAGNSRVVAGVHWPSDVEAGR 197

                         90
                 ....*....|
gi 691141162 163 LIGAAVAAMI 172
Cdd:cd03380  198 ILGEAIAAAL 207
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 67-170 4.30e-16

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 70.53  E-value: 4.30e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162   67 YLLLGGSVGTAIYKFLKHKTTRPRPYQVHQVIVLGERPLDHF----SFPSGHTLHAVMVTIVLGYIQP--------VLLA 134
Cdd:pfam01569   1 ILLLALALAGLLSSVLKDYFGRPRPFFLLLEGGLVPAPSTLPglgySFPSGHSATAFALALLLALLLRrlrkivrvLLAL 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 691141162  135 AMFPFMVLVALSRMVLGLHYPSDVIVGALIGAAVAA 170
Cdd:pfam01569  81 LLLVLALLVGLSRLYLGVHFPSDVLAGALIGILLAL 116
PAP2_like_2 cd03392
PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 33-179 1.34e-15

PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239486  Cd Length: 182  Bit Score: 70.72  E-value: 1.34e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  33 FFKIISRVGDGPF---WYLMLAIVWGMQGitYSLQIIYLLLGGSVGTAIYKFLKHKTTRPRPYQVHQVIVLGerpldhFS 109
Cdd:cd03392   31 FMTAITFLGSPAVlliIVLLLALLLLLKR--RRRAALFLLLALLGGGALNTLLKLLVQRPRPPLHLLVPEGG------YS 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162 110 FPSGHTLHAVMVTIVLGYI-----------QPVLLAAMFpFMVLVALSRMVLGLHYPSDVIVGALIGAAVAAMIIFVAPL 178
Cdd:cd03392  103 FPSGHAMGATVLYGFLAYLlarrlprrrvrILLLILAAI-LILLVGLSRLYLGVHYPSDVLAGWLLGLAWLALLILLYRR 181


                 .
gi 691141162 179 L 179
Cdd:cd03392  182 L 182
PAP2_like_4 cd03395
PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 10-176 1.61e-15

PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239489  Cd Length: 177  Bit Score: 70.37  E-value: 1.61e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  10 ILDLDLRGCLYLNNFSHSQRVALFFKIISRVGDGPFWYLMLAIVWGMQGiTYSLQIIYLLLGGSVGTAIY---KFLKHKT 86
Cdd:cd03395    2 LEQIDVWLFLLLNGTLVHPLLDDLMPFLTGKKLSVPIFLLLALFILFRK-GPIGLLILLLVLLAVGFADQlasGFLKPLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  87 TRPRPYQVHQ---VIVLGERPlDHFSFPSGHT--LHAVMVTIVLGYIQPVLLAAMFPFMVLVALSRMVLGLHYPSDVIVG 161
Cdd:cd03395   81 ARLRPCNALDgvrLVVLGDQG-GSYSFASSHAanSFALALFIWLFFRRGLFSPVLLLWALLVGYSRVYVGVHYPGDVIAG 159

                        170
                 ....*....|....*
gi 691141162 162 ALIGAAVAAMIIFVA 176
Cdd:cd03395  160 ALIGIISGLLFYLLF 174
PAP2_acid_phosphatase cd03397
PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes ...
 88-170 2.15e-14

PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains to be determined.


Pssm-ID: 239491  Cd Length: 232  Bit Score: 68.52  E-value: 2.15e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  88 RPRPYQVH-QVIVLGE---RPLDHFSFPSGHTLHAVMVTIVLGYIQP----VLLAAMFPFmvlvALSRMVLGLHYPSDVI 159
Cdd:cd03397  126 RPRPFVLNdEPICTPPdesGLAKDGSYPSGHTAAGYAWALILAELVPeradEILARGSEY----GQSRIVCGVHWPSDVM 201

                         90
                 ....*....|.
gi 691141162 160 VGALIGAAVAA 170
Cdd:cd03397  202 GGRIMAAALVA 212
PAP2_lipid_A_1_phosphatase cd03389
PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from ...
 30-175 5.72e-13

PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from Francisella novicida selectively dephosphorylates lipid A at the 1-position. Lipid A is the membrane-anchor component of lipopolysaccharides (LPS), the major constituents of the outer membrane in many gram-negative bacteria.


Pssm-ID: 239483  Cd Length: 186  Bit Score: 63.88  E-value: 5.72e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  30 VALFFKIISRVGDGPfWYLMLAIV----------------WGMQGITYSLQIIYLLLGGSVGTAIYKFLKHKTTRPRPYQ 93
Cdd:cd03389   21 LAGFFRTITDFGKSG-WYLIPSLLlfllfrfgdlrglsapSRARFPKAAWAGLFLFATVALSGILVNLLKFIIGRARPKL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  94 VHQVIVLGerpLDHF-------SFPSGHTLHAVMVTIVLGYIQPVLLAAMFPFMVLVALSRMVLGLHYPSDVIVGALIGA 166
Cdd:cd03389  100 LFDDGLYG---FDPFhadyaftSFPSGHSATAGAAAAALALLFPRYRWAFILLALLIAFSRVIVGAHYPSDVIAGSLLGA 176


                 ....*....
gi 691141162 167 AVAAMIIFV 175
Cdd:cd03389  177 VTALALYQR 185
acidPPc smart00014
Acid phosphatase homologues;
81-170 6.76e-12

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 59.28  E-value: 6.76e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162    81 FLKHKTTRPRPYQV--HQVIVLGERPLDH---FSFPSGHTLHAVMVTIVLGYIQP------VLLAAMFPFMVLVALSRMV 149
Cdd:smart00014  13 VIKNYFGRPRPFFLsiGDACCTPNFLLTLeagYSFPSGHTAFAFAFALFLLLYLParagrkLLIFLLLLLALVVGFSRVY 92

                           90       100
                   ....*....|....*....|.
gi 691141162   150 LGLHYPSDVIVGALIGAAVAA 170
Cdd:smart00014  93 LGAHWPSDVLAGSLLGILIAA 113
PAP2_SPPase1 cd03388
PAP2_like proteins, sphingosine-1-phosphatase subfamily. Sphingosine-1-phosphatase is an ...
 32-170 5.41e-11

PAP2_like proteins, sphingosine-1-phosphatase subfamily. Sphingosine-1-phosphatase is an intracellular enzyme located in the endoplasmic reticulum, which regulates the level of sphingosine-1-phosphate (S1P), a bioactive lipid. S1P acts as a second messenger in the cell, and extracellularly by binding to G-protein coupled receptors of the endothelial differentiation gene family.


Pssm-ID: 239482  Cd Length: 151  Bit Score: 57.63  E-value: 5.41e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  32 LFFKIISRVGDGPFWYLMLAIVWGMQGITYSLQIIYLLlggSVGTAIYKFLKHKTTRPRPYQVHQV-IVLGERPLDhFSF 110
Cdd:cd03388    5 YYFAFTALLGTHTFYILFLPFLFWNGDPYVGRDLVVVL---ALGMYIGQFIKDLFCLPRPSSPPVVrLTMSSAALE-YGF 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 691141162 111 PSGHTLHAVMVTIVLG--------YIQPVLLAAMFPFMVLVALSRMVLGLHYPSDVIVGALIGAAVAA 170
Cdd:cd03388   81 PSTHAMNATAISFYLLiylydryqYPFVLGLILALFYSTLVCLSRIYMGMHSVLDVIAGSLIGVLILL 148
PAP2_containing_2_like cd03391
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. ...
 34-165 6.07e-11

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a membrane-associated phosphatidic acid phosphatase.


Pssm-ID: 239485 [Multi-domain]  Cd Length: 159  Bit Score: 57.71  E-value: 6.07e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  34 FKIISRVGDGPFWyLMLAIVWGMQGITYSLQ--IIYLLLGGSVGTAIYKFLKHKTTRPRPYQVHQVIVLgERPLDHFSFP 111
Cdd:cd03391   17 VKLLELSGHGIPW-LAGTISCLWISSSPAGQevLVNLLLGLLLDIITVAILKALVRRRRPAYNSPDMLD-YVAVDKYSFP 94

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 691141162 112 SGHTLHAVMVTIVLGYIQPV---LLAAMFPFMVLVALSRMVLGLHYPSDVIVGALIG 165
Cdd:cd03391   95 SGHASRAAFVARFLLNHLVLavpLRVLLVLWATVVGISRVLLGRHHVLDVLAGAFLG 151
PAP2_like_5 cd03394
PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 67-170 1.39e-09

PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239488 [Multi-domain]  Cd Length: 106  Bit Score: 53.10  E-value: 1.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  67 YLLLGGSVGTAIYKFLKHKTTRPRPYqvhqvivlgERPLDHFSFPSGHTLHAVMVTIVLGYIQPVLLAAMFPFMV--LVA 144
Cdd:cd03394    7 ILAEAAALTAAVTEGLKFAVGRARPD---------GSNNGYRSFPSGHTASAFAAATFLQYRYGWRWYGIPAYALasLVG 77

                         90       100
                 ....*....|....*....|....*.
gi 691141162 145 LSRMVLGLHYPSDVIVGALIGAAVAA 170
Cdd:cd03394   78 ASRVVANRHWLSDVLAGAAIGILVGY 103
PAP2_like_3 cd03393
PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 66-172 2.48e-09

PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria and archaea, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239487 [Multi-domain]  Cd Length: 125  Bit Score: 52.76  E-value: 2.48e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  66 IYLLLGGSVGTAIYKFLKHKTTRPRPYQVHQVIVLGERPLDHFSFPSGHTLHAVMV--TIVLGYIQPVLLAAMFPFMVLV 143
Cdd:cd03393   16 RYLGLALCASGYLNAALKEVFKIPRPFTYDGIQAIYEESAGGYGFPSGHAQTSATFwgSLMLHVRKKWFTLIGVVLVVLI 95

                         90       100
                 ....*....|....*....|....*....
gi 691141162 144 ALSRMVLGLHYPSDVIVGALIGAAVAAMI 172
Cdd:cd03393   96 SFSRLYLGVHWPSDVIGGVLIGLLVLVLG 124
PRK10699 PRK10699
phosphatidylglycerophosphatase B; Provisional
 108-176 2.33e-06

phosphatidylglycerophosphatase B; Provisional


Pssm-ID: 182658  Cd Length: 244  Bit Score: 46.18  E-value: 2.33e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 691141162 108 FSFPSGHTLHAV-MVTIVLGYIQP----VLLAAMFPFMVLVALSRMVLGLHYPSDVIVGALIGAAVAAMIIFVA 176
Cdd:PRK10699 157 FAFPSGHTMFAAsWALLAVGLLWPrrryKTVALLMLWATGVMGSRLLLGMHWPRDLVVATLISWLLVTVATWLA 230
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 109-173 2.45e-06

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


Pssm-ID: 239479  Cd Length: 150  Bit Score: 45.31  E-value: 2.45e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 691141162 109 SFPSGHTLHAV--MVTIVLgYIQ------------PVLLAAMFPFMVLVALSRMVLGLHYPSDVIVGALIGAAVAAMII 173
Cdd:cd03384   73 SFPSGHASLSMyaAVFLAL-YLQarlklrgsrllrPLLQFLLLALALYVGLSRISDYKHHWSDVLAGALLGSVIALFLV 150
PAP2_haloperoxidase cd03398
PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as ...
 107-172 3.51e-06

PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen peroxide forming dioxygen. They are likely to participate in the biosynthesis of halogenated natural products, such as volatile halogenated hydrocarbons, chiral halogenated terpenes, acetogenins and indoles.


Pssm-ID: 239492  Cd Length: 232  Bit Score: 45.49  E-value: 3.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162 107 HFSFPSGH---------TLHA----------VMVTIVLGYIQPVLL--AAMFPFMVLVALSRMVLGLHYPSDVIVGALIG 165
Cdd:cd03398  144 HPSYPSGHatfagaaatVLKAlfgsdkvpdtVSEPDEGGPSTGVTRvwAELNELADEVAISRVYAGVHFRSDDAAGAALG 223


                 ....*..
gi 691141162 166 AAVAAMI 172
Cdd:cd03398  224 EQIGAAA 230
PAP2_BcrC_like cd03385
PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as ...
 48-174 4.11e-06

PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from Bacillus subtilis posesses undecaprenyl pyrophosphate (UPP) phospatase activity, and it is hypothesized that it competes with bacitracin for UPP, increasing the cell's resistance to bacitracin.


Pssm-ID: 239480  Cd Length: 144  Bit Score: 44.56  E-value: 4.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  48 LMLAIVWGMQGITYSLQIIYLLLGGSVGTAIYKFLKHKTTRPRPYQVHQVIVLGERPLDHfSFPSGHTLHAVMVTIVL-- 125
Cdd:cd03385   18 LLLVVLWLWGGEKQRKVVLFATIAVAVALLINYIIGLLYFHPRPFVVGLGHNLLPHAADS-SFPSDHTTLFFSIAFSLll 96

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 691141162 126 -GYIQPVLLAAMFPFmvLVALSRMVLGLHYPSDVIVGALIGAAVAAMIIF 174
Cdd:cd03385   97 rRRKWAGWILLILAL--LVAWSRIYLGVHYPLDMLGAALVAVLSALLVFQ 144
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 109-172 1.91e-05

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 43.36  E-value: 1.91e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 691141162 109 SFPSGH--TLHAVMVTIVL---GYIQP--------VLLAAMFPFMV--LVALSRMVLGLHYPSDVIVGALIGAAVAAMI 172
Cdd:cd03390  111 SFPSGHssFAFAGLGFLSLylaGKLHIfdprgsswRLLLALLPLLLaiLVAVSRTRDYRHHFSDVIAGSLIGLIIAYLS 189
PAP2_like_6 cd03396
PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 61-172 3.21e-05

PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239490  Cd Length: 197  Bit Score: 42.67  E-value: 3.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  61 YSLQIIYLLLGGSVGTAIYKFLKHKTTRPRPYQVHQV------IVLGERPLD----HFSFPSGHT-------LHAVMVTI 123
Cdd:cd03396   65 RRRALLLLILVIGLGLLVVAILKSHWGRPRPWDLTEFggdapyTPLFSGPSNgcgkGCSFPSGHAsagfallALYFLFRR 144

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 691141162 124 VLGYIQPVLLAAMFPFMVLVALSRMVLGLHYPSDVIVGALIGAAVAAMI 172
Cdd:cd03396  145 RRPRLARLVLAAGLALGALMGLARMARGAHFLSDVLWSLLLVWLIALLL 193
PLN02525 PLN02525
phosphatidic acid phosphatase family protein
 33-170 3.08e-04

phosphatidic acid phosphatase family protein


Pssm-ID: 215288  Cd Length: 352  Bit Score: 40.11  E-value: 3.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  33 FFKIISRVGDGPFWYLMLAIV-WGMQGITYSLQIIYLLLGGSVGTAIykflKHKTTRPRPYQ--VHQVIVLG--ERPLDH 107
Cdd:PLN02525   8 FFSGLSCVVSVPFYTAFLPLLfWSGHGKLARQMTLLMAFCDYVGNCI----KDVVSAPRPSCppVRRVTATKdeEENAME 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 691141162 108 FSFPSGHTLHAV-----MVTIVLGYIQPV------LLAAMFPFMV-LVALSRMVLGLHYPSDVIVGALIGAAVAA 170
Cdd:PLN02525  84 YGLPSSHTLNTVclsgyLLHYVLSYLQNVdasvifAGLALFCLLVaLVGFGRLYLGMHSPIDIIAGLAIGLVILA 158
PAP2_3 pfam14378
PAP2 superfamily;
109-170 4.24e-04

PAP2 superfamily;


Pssm-ID: 433919  Cd Length: 190  Bit Score: 39.24  E-value: 4.24e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 691141162  109 SFPSGHTLHAVMVTIVLGYI--QPVLLAAMFPFMVLVALSRMVLGLHYPSDVIVGALIGAAVAA 170
Cdd:pfam14378 126 AMPSLHVAWALLCALALWRLrrTRILRWLAVAYNVLMIVSTVATGNHYLLDVVAGVALALAAIA 189
PAP2_dolichyldiphosphatase cd03382
PAP2_like proteins, dolichyldiphosphatase subfamily. Dolichyldiphosphatase is a ...
 59-171 1.01e-03

PAP2_like proteins, dolichyldiphosphatase subfamily. Dolichyldiphosphatase is a membrane-associated protein located in the endoplasmic reticulum and hydrolyzes dolichyl pyrophosphate, as well as dolichylmonophosphate at a low rate. The enzyme is necessary for maintaining proper levels of dolichol-linked oligosaccharides and protein N-glycosylation, and might play a role in re-utilization of the glycosyl carrier lipid for additional rounds of lipid intermediate biosynthesis after its release during protein N-glycosylation reactions.


Pssm-ID: 239477  Cd Length: 159  Bit Score: 38.02  E-value: 1.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691141162  59 ITYSLQIIYLLLGGSVGTAIYKFLKHKTTRPRPYQVHQVIVLGerpldhFSFPSGH--------TLHAVMVTIVLG---- 126
Cdd:cd03382   38 FRRELEAIYLFIGLLANEALNYVLKRIIKEPRPCSGAYFVRSG------YGMPSSHsqfmgffaVYLLLFIYLRLGrlns 111

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 691141162 127 YIQPVLLAAMFPFM-VLVALSRMVLGLHYPSDVIVGALIGAAVAAM 171
Cdd:cd03382  112 LVSRFLLSLGLLLLaLLVSYSRVYLGYHTVSQVVVGAIVGILLGIL 157
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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