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Conserved domains on  [gi|692117566|ref|WP_032074436|]
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MULTISPECIES: amino acid ABC transporter permease [Pseudomonas]

Protein Classification

amino acid ABC transporter permease( domain architecture ID 11433582)

amino acid ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which binds and transports amino acids

Gene Ontology:  GO:0140359|GO:0042626|GO:0006865
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 1-215 9.02e-77

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 229.96  E-value: 9.02e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566   1 MMDFT-LWDILRNLLIGLQWTVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVALM 79
Cdd:COG0765    2 FFDFSvLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPLL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  80 GMNISPWAAAALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAPTVGFSVQVVKGTA 159
Cdd:COG0765   82 GIDLSPFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFISLLKDTS 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 692117566 160 VTSIIGFTELTKTGSMLANATFEPFMVYGFVALGYFILCYPLSLCARHLERRLHAS 215
Cdd:COG0765  162 LVSVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRLARG 217
 
Name Accession Description Interval E-value
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 1-215 9.02e-77

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 229.96  E-value: 9.02e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566   1 MMDFT-LWDILRNLLIGLQWTVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVALM 79
Cdd:COG0765    2 FFDFSvLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPLL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  80 GMNISPWAAAALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAPTVGFSVQVVKGTA 159
Cdd:COG0765   82 GIDLSPFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFISLLKDTS 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 692117566 160 VTSIIGFTELTKTGSMLANATFEPFMVYGFVALGYFILCYPLSLCARHLERRLHAS 215
Cdd:COG0765  162 LVSVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRLARG 217
PRK15100 PRK15100
cystine ABC transporter permease;
13-212 1.37e-40

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 137.96  E-value: 1.37e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  13 LLIGLQWTVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVALMGMNISPWAAAALA 92
Cdd:PRK15100  15 LLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYVSIFRGTPLIAQLFMIYYGLPQFGIELDPIPAAMIG 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  93 LTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAPTVGFSVQVVKGTAVTSIIGFTELTKT 172
Cdd:PRK15100  95 LSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKDTSLAATIQVPELFRQ 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 692117566 173 GSMLANATFEPFMVYGFVALGYFILCYPLSLCARHLERRL 212
Cdd:PRK15100 175 AQLITSRTLEVFTMYLAASLIYWIMATVLSALQNRFENQL 214
ectoine_ehuC TIGR03004
ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are ...
 9-212 2.14e-30

ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons. Permease subunits EhuC and EhuD are homologous.


Pssm-ID: 132049 [Multi-domain]  Cd Length: 214  Bit Score: 111.48  E-value: 2.14e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566    9 ILRNLLIGLQWTVALSLVAFIGGGLIGLLvmgmRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVALMGMNISPWAA 88
Cdd:TIGR03004   7 LLQGAWVTMQITLAGSVLATVLAFFAGLG----RVSGGPILRTVALCYIEVFRGTSLLVQLFWFYFVLPLIGLSLDPVTT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566   89 AALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAPTVGFSVQVVKGTAVTSIIGFTE 168
Cdd:TIGR03004  83 GVMVLGLHAGAYGAEIVRGALSSVSVQQLEACRALNFTRFQTLRRISLPQALVEMMPAFGNLAIELLKLTSLVSLISLAD 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 692117566  169 LTKTGSMLANATFEPFMVYGFVALGYFILCYPLSLCARHLERRL 212
Cdd:TIGR03004 163 LTFAAQSIRNLTLDTLSIFAITLLCYFVMALIIMLIMRVLERVV 206
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 17-197 7.53e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.53  E-value: 7.53e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  17 LQWTVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVALMG---MNISPWAAAALAL 93
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLgwgILPGLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  94 TLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAPTVGFSVQVVKGTAVTSIIGFTELTKTG 173
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170       180
                 ....*....|....*....|....
gi 692117566 174 SMLANATFEPFMVYGFVALGYFIL 197
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALI 184
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 56-212 2.69e-05

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 43.06  E-value: 2.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566   56 YIELFQGTPLLMqLFLVFFGVALMGMNISPWAAAALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVI 135
Cdd:pfam00528  23 LIDLLQALPSFV-LAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKII 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  136 LPQALRIAVAPTVGFSVQVVKGTAVTSIIGftELTKTGSMLANATFE---PFMVYGFVALG--YFILCYPLSLCARHLER 210
Cdd:pfam00528 102 LPNALPPILTGLALAFGGALGGAVLLEFLG--SWPGLGLLLIEAILGydyPEIQGPVLAAAliLLLLNLLVDILQRLLDP 179


                  ..
gi 692117566  211 RL 212
Cdd:pfam00528 180 RV 181
 
Name Accession Description Interval E-value
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 1-215 9.02e-77

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 229.96  E-value: 9.02e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566   1 MMDFT-LWDILRNLLIGLQWTVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVALM 79
Cdd:COG0765    2 FFDFSvLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPLL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  80 GMNISPWAAAALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAPTVGFSVQVVKGTA 159
Cdd:COG0765   82 GIDLSPFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFISLLKDTS 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 692117566 160 VTSIIGFTELTKTGSMLANATFEPFMVYGFVALGYFILCYPLSLCARHLERRLHAS 215
Cdd:COG0765  162 LVSVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRLARG 217
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 2-214 1.16e-43

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 146.01  E-value: 1.16e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566   2 MDF-TLWDILRNLLIGLQWTVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVA--- 77
Cdd:COG4160    1 MDLdLLFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYYGLGqfe 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  78 ------LMGMNISPWAAAALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAPTVGFS 151
Cdd:COG4160   81 wvreswLWPLLRDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILPSALRRALPAYSNEV 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 692117566 152 VQVVKGTAVTSIIGFTELTKTGSMLANATFEPFMVYGFVALGYFILCYPLSLCARHLERRLHA 214
Cdd:COG4160  161 ILMLKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRLLR 223
PRK15100 PRK15100
cystine ABC transporter permease;
13-212 1.37e-40

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 137.96  E-value: 1.37e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  13 LLIGLQWTVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVALMGMNISPWAAAALA 92
Cdd:PRK15100  15 LLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYVSIFRGTPLIAQLFMIYYGLPQFGIELDPIPAAMIG 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  93 LTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAPTVGFSVQVVKGTAVTSIIGFTELTKT 172
Cdd:PRK15100  95 LSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKDTSLAATIQVPELFRQ 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 692117566 173 GSMLANATFEPFMVYGFVALGYFILCYPLSLCARHLERRL 212
Cdd:PRK15100 175 AQLITSRTLEVFTMYLAASLIYWIMATVLSALQNRFENQL 214
ectoine_ehuC TIGR03004
ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are ...
 9-212 2.14e-30

ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons. Permease subunits EhuC and EhuD are homologous.


Pssm-ID: 132049 [Multi-domain]  Cd Length: 214  Bit Score: 111.48  E-value: 2.14e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566    9 ILRNLLIGLQWTVALSLVAFIGGGLIGLLvmgmRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVALMGMNISPWAA 88
Cdd:TIGR03004   7 LLQGAWVTMQITLAGSVLATVLAFFAGLG----RVSGGPILRTVALCYIEVFRGTSLLVQLFWFYFVLPLIGLSLDPVTT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566   89 AALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAPTVGFSVQVVKGTAVTSIIGFTE 168
Cdd:TIGR03004  83 GVMVLGLHAGAYGAEIVRGALSSVSVQQLEACRALNFTRFQTLRRISLPQALVEMMPAFGNLAIELLKLTSLVSLISLAD 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 692117566  169 LTKTGSMLANATFEPFMVYGFVALGYFILCYPLSLCARHLERRL 212
Cdd:TIGR03004 163 LTFAAQSIRNLTLDTLSIFAITLLCYFVMALIIMLIMRVLERVV 206
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 2-213 8.05e-30

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 110.15  E-value: 8.05e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566   2 MDF---TLWDILRNLLIGLQWTVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVAL 78
Cdd:PRK09494   1 MQFdwsAIWPAIPLLLEGAKMTLWISVLGLAGGLVIGLLAGFARAYGGWIANHIALVFIELIRGTPIVVQVMFIYFALPM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  79 M--GMNISPWAAAALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAPTVGFSVQVVK 156
Cdd:PRK09494  81 AfnDLRIDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRRETLRYVIGPLALRRMLPPLGNQWIISIK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 692117566 157 GTAVTSIIGFTELTKTGSMLANATFEPFMVYGFVALGYFILCYPLSLCARHLERRLH 213
Cdd:PRK09494 161 DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVIYLIITLVLSFILRRLERRMK 217
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 9-212 3.53e-25

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 97.62  E-value: 3.53e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566    9 ILRNLLIGLQWTVALSLVAFIGGGLIGL-LVMGMRTSEKTGPRVTAkLYIELFQGTPLLMQLFLVFFGVALMGMNISPWA 87
Cdd:TIGR03003   9 ILPTLIEGLKITILATALGFAIAAVLGLvFAILRRSAPTPISWPTS-FVVEFIRGTPLLVQLYFLYYVLPDIGIRLPALV 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566   88 AAALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAPTVGFSVQVVKGTAVTSIIGFT 167
Cdd:TIGR03003  88 AGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLVAMFKETPVLSAITVL 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 692117566  168 ELTKTGSMLANATFEPFMVYGFVALGYFILCYPLSLCARHLERRL 212
Cdd:TIGR03003 168 ELMNQAKSIGNSTFRYLEPMTLVGVFFLILSIISVFFLRRLEARL 212
HEQRo_perm_3TM TIGR01726
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ...
 9-107 2.68e-21

amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130787 [Multi-domain]  Cd Length: 99  Bit Score: 84.12  E-value: 2.68e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566    9 ILRNLLIGLQWTVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVALMGMNISPWAA 88
Cdd:TIGR01726   1 NLPFLLKGLLLTLLLSVLSILLGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIYFGLPLIGIRLSPLTA 80

                          90
                  ....*....|....*....
gi 692117566   89 AALALTLFTSAYLAEIWRG 107
Cdd:TIGR01726  81 AVIALTLFYGAYLAEIFRG 99
artM PRK11122
arginine ABC transporter permease ArtM;
6-211 7.52e-21

arginine ABC transporter permease ArtM;


Pssm-ID: 182978 [Multi-domain]  Cd Length: 222  Bit Score: 86.55  E-value: 7.52e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566   6 LWDILRNLLIGLQWTVALSLVAFIGGgLIGLLVMGMRTsektgPRVT--AKLYIELFQGTPLLMQLFLVFFG-------- 75
Cdd:PRK11122   5 LPELLKGLHTSLTLTVASLLVALVLA-LIFTIILTLKT-----PVLVwlVRGYITLFTGTPLLVQIFLIYYGpgqfpwlq 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  76 --VALMGMNISPWAAAALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRyVILPQALRIAVAPTVGFSVQ 153
Cdd:PRK11122  79 eyPWLWHLLSQPWLCAMLALALNSAAYSTQLFYGAVRAIPEGQWQSCAALGMSKKQTLR-ILLPYAFKRALSSYSNEVVL 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 692117566 154 VVKGTAVTSIIGFTELTKTGSMLANATFEpFMVYGFVALGYFILCYPLSLCARHLERR 211
Cdd:PRK11122 158 VFKSTSLAYTITLMDVMGYSQLLYGRTYD-VMVFGAAGIIYLVVNGLLTLLMRLIERK 214
PRK15069 PRK15069
histidine ABC transporter permease HisM;
4-211 1.36e-16

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 75.47  E-value: 1.36e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566   4 FTLWDILRnlLIGLQWTVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVALM---- 79
Cdd:PRK15069  12 LLWTDGYR--FTGLAITLWLLVASVVIGFVLAVPLAIARVSSNKWIRFPVWLYTYVFRGTPLYVQLLVFYTGMYSLeivr 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  80 -----------GMNISpwaaaALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAptv 148
Cdd:PRK15069  90 gtdlldaffrsGLNCT-----ILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALP--- 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 692117566 149 GFSVQVVKGTAVTSiIGFT----ELTKTGSMLANATFEPFMVYGFVALGYFILCYPLSLCARHLERR 211
Cdd:PRK15069 162 AYSNEVILMLHATT-LAFTatvpDILKIARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAERR 227
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
13-211 5.23e-16

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 73.71  E-value: 5.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  13 LLIGLQWTVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQL---FLVFFGVALMGMNISP---- 85
Cdd:PRK15107  16 LLDGLVITLKITVTAVVIGILWGTILAVMRLSSFKPVAWFAKAYVNVFRSIPLVMVLlwfYLIVPGFLQNVLGLSPktdi 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  86 -WAAAALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAPTVGFSVQVVKGTAVTSII 164
Cdd:PRK15107  96 rLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLTQGIVLFQDTSLVYVL 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 692117566 165 GFTELTKTGSMLANATFEPFMVYGFVALGYFILCYPLSLCARHLERR 211
Cdd:PRK15107 176 SLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSYLKKR 222
BatB COG4597
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 16-146 7.23e-16

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443651 [Multi-domain]  Cd Length: 397  Bit Score: 75.18  E-value: 7.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  16 GLQWTVALSLVAFIGGglIGLLVMGMRTSEKTGPRVTAKLY-IELFQGTPLLMqlfLVFFGVALM-------------GM 81
Cdd:COG4597  185 GFGWVLAALLAAIVAA--FVLRRWARRRQEATGQRFPVWWIsLALLVGLPLLA---FLLLGAPLSldypelkgfnfrgGL 259

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 692117566  82 NISP-WAAAALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAP 146
Cdd:COG4597  260 TLSPeFVALLLALSLYTAAFIAEIVRAGIQAVSKGQTEAARALGLRPGQTLRLVVLPQALRVIIPP 325
PRK11123 PRK11123
arginine ABC transporter permease ArtQ;
20-197 4.75e-15

arginine ABC transporter permease ArtQ;


Pssm-ID: 182979 [Multi-domain]  Cd Length: 238  Bit Score: 71.25  E-value: 4.75e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  20 TVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFG------------------------ 75
Cdd:PRK11123  14 TVGLAVCALIVGLALAMLFAVWESAKWRPVAWPGTALVTLLRGLPEILVVLFIYFGssqllltlsdgftlnlgfvqipvq 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  76 VALMGMNISPWAAAALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAptvGFSVQ-- 153
Cdd:PRK11123  94 MDIENFEVSPFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALP---GLGNQwl 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 692117566 154 -VVKGTAVTSIIGFTELTKTGSMLANATFEPFMVYGFVALGYFIL 197
Cdd:PRK11123 171 vLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIIAAAIYLVI 215
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 17-197 7.53e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.53  E-value: 7.53e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  17 LQWTVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVALMG---MNISPWAAAALAL 93
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLgwgILPGLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  94 TLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVAPTVGFSVQVVKGTAVTSIIGFTELTKTG 173
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170       180
                 ....*....|....*....|....
gi 692117566 174 SMLANATFEPFMVYGFVALGYFIL 197
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALI 184
PRK15135 PRK15135
histidine ABC transporter permease HisQ;
13-184 7.14e-11

histidine ABC transporter permease HisQ;


Pssm-ID: 185089 [Multi-domain]  Cd Length: 228  Bit Score: 59.42  E-value: 7.14e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  13 LLIGLQWTVALSLVAFIGGGLIGLLVMGMRTSEKTGPRVTAKLYIELFQGTPLLMQLFLVFFGVAL--------MGM--- 81
Cdd:PRK15135   9 ILQGALVTLELALSSVVLAVIIGLIGAGGKLSQNRLLGLIFEGYTTLIRGVPDLVLMLLIFYGLQIalnsvteaLGVgqi 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  82 NISPWAAAALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVILPQALRIAVaPTVGFSVQVV-KGTAV 160
Cdd:PRK15135  89 DIDPMVAGIITLGFIYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYAL-PGIGNNWQVIlKATAL 167

                        170       180
                 ....*....|....*....|....
gi 692117566 161 TSIIGFTELTKTGSMLANATFEPF 184
Cdd:PRK15135 168 VSLLGLEDVVKATQLAGKSTWEPF 191
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 56-212 2.69e-05

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 43.06  E-value: 2.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566   56 YIELFQGTPLLMqLFLVFFGVALMGMNISPWAAAALALTLFTSAYLAEIWRGCVESISKGQWEASASLAMTPFEQMRYVI 135
Cdd:pfam00528  23 LIDLLQALPSFV-LAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKII 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 692117566  136 LPQALRIAVAPTVGFSVQVVKGTAVTSIIGftELTKTGSMLANATFE---PFMVYGFVALG--YFILCYPLSLCARHLER 210
Cdd:pfam00528 102 LPNALPPILTGLALAFGGALGGAVLLEFLG--SWPGLGLLLIEAILGydyPEIQGPVLAAAliLLLLNLLVDILQRLLDP 179


                  ..
gi 692117566  211 RL 212
Cdd:pfam00528 180 RV 181
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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