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Conserved domains on  [gi|695734550|ref|WP_032661025|]
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MULTISPECIES: helix-turn-helix domain-containing protein [Enterobacter]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 11443570)

helix-turn-helix domain-containing protein such as an XRE (Xenobiotic Response Element) family transcriptional regulator

Gene Ontology:  GO:0003677
PubMed:  37972151

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
74-121 3.74e-11

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


:

Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 55.39  E-value: 3.74e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 695734550  74 AWRILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYGC 121
Cdd:COG1396   14 ELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGV 61
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
74-121 3.74e-11

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 55.39  E-value: 3.74e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 695734550  74 AWRILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYGC 121
Cdd:COG1396   14 ELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGV 61
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 74-121 9.26e-11

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 53.71  E-value: 9.26e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 695734550  74 AWRILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYGC 121
Cdd:cd00093    6 ELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGV 53
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
73-122 5.81e-10

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 51.36  E-value: 5.81e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 695734550    73 AAWRILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYGCK 122
Cdd:smart00530   3 KELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVS 52
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 73-122 8.05e-10

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 51.00  E-value: 8.05e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 695734550   73 AAWRILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYGCK 122
Cdd:pfam01381   2 KELREELGLSQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVS 51
PRK09943 PRK09943
HTH-type transcriptional regulator PuuR;
73-120 8.57e-05

HTH-type transcriptional regulator PuuR;


Pssm-ID: 182158 [Multi-domain]  Cd Length: 185  Bit Score: 40.16  E-value: 8.57e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 695734550  73 AAWRILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYG 120
Cdd:PRK09943  13 SEIRQQQGLSQRRAAELSGLTHSAISTIEQDKVSPAISTLQKLLKVYG 60
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
 75-116 5.90e-04

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 37.71  E-value: 5.90e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 695734550   75 WRILRGMSQQEVAEKLGITQSAVSQLealdsrpQKRTREKLA 116
Cdd:TIGR02937 121 LRYLEGLSYKEIAEILGISVGTVKRR-------LKRARKKLR 155
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
74-121 3.74e-11

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 55.39  E-value: 3.74e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 695734550  74 AWRILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYGC 121
Cdd:COG1396   14 ELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGV 61
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 74-121 9.26e-11

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 53.71  E-value: 9.26e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 695734550  74 AWRILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYGC 121
Cdd:cd00093    6 ELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGV 53
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
73-122 5.81e-10

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 51.36  E-value: 5.81e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 695734550    73 AAWRILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYGCK 122
Cdd:smart00530   3 KELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVS 52
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
74-126 6.58e-10

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 51.77  E-value: 6.58e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 695734550  74 AWRILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYGCKQEQI 126
Cdd:COG1476   11 ELRKERGLTQEELAELLGVSRQTISAIENGKYNPSLELALKIARALGVSLEEL 63
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 73-122 8.05e-10

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 51.00  E-value: 8.05e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 695734550   73 AAWRILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYGCK 122
Cdd:pfam01381   2 KELREELGLSQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVS 51
aMBF1 COG1813
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ...
 76-122 1.73e-08

Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441418 [Multi-domain]  Cd Length: 70  Bit Score: 48.01  E-value: 1.73e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 695734550  76 RILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYGCK 122
Cdd:COG1813   21 REARGLSQEELAEKLGVSESTIRRIERGEATPSLDTLRKLEKALGIS 67
AF2118 COG3620
Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain ...
 62-128 8.80e-08

Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) [Transcription];


Pssm-ID: 442838 [Multi-domain]  Cd Length: 95  Bit Score: 46.94  E-value: 8.80e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 695734550  62 DVMHNE------NVSLQAAWRILR---GMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYGCKQEQISL 128
Cdd:COG3620    3 DLMSRDvvtvspDDTLGEALRLMRkelGLSQLPVAELVGVSQSDILRIESGKRDPTVSTLEKIAEALGKELSAVLV 78
AF0184 COG2522
Predicted transcriptional regulator, contains XRE-type HTH domain [Transcription];
79-99 9.16e-08

Predicted transcriptional regulator, contains XRE-type HTH domain [Transcription];


Pssm-ID: 442012 [Multi-domain]  Cd Length: 99  Bit Score: 46.74  E-value: 9.16e-08
                         10        20
                 ....*....|....*....|.
gi 695734550  79 RGMSQQEVAEKLGITQSAVSQ 99
Cdd:COG2522   27 RGLSQSEIAKLLGITQAAVSQ 47
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 73-126 1.06e-05

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 40.59  E-value: 1.06e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 695734550   73 AAWRILRGMSQQEVAEKLGITQSAVSQLEA-LDSRPQKRTREKLAAIYGCKQEQI 126
Cdd:pfam13560   7 RRLRERAGLSQEALARRLGVSRSTLSRLETgRRGRPSPAVVERLARALGVDGAER 61
PRK09943 PRK09943
HTH-type transcriptional regulator PuuR;
73-120 8.57e-05

HTH-type transcriptional regulator PuuR;


Pssm-ID: 182158 [Multi-domain]  Cd Length: 185  Bit Score: 40.16  E-value: 8.57e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 695734550  73 AAWRILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYG 120
Cdd:PRK09943  13 SEIRQQQGLSQRRAAELSGLTHSAISTIEQDKVSPAISTLQKLLKVYG 60
YiaG COG2944
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
76-119 1.37e-04

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 37.61  E-value: 1.37e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 695734550  76 RILR---GMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIY 119
Cdd:COG2944   12 RALRerlGLSQAEFAALLGVSVSTVRRWEQGRRKPSGAALKLLRLLE 58
COG5606 COG5606
Predicted DNA-binding protein, XRE-type HTH domain [General function prediction only];
79-100 1.76e-04

Predicted DNA-binding protein, XRE-type HTH domain [General function prediction only];


Pssm-ID: 444337  Cd Length: 105  Bit Score: 38.33  E-value: 1.76e-04
                         10        20
                 ....*....|....*....|..
gi 695734550  79 RGMSQQEVAEKLGITQSAVSQL 100
Cdd:COG5606   44 RGLTQAEAAELLGITQPRVSDL 65
Sigma70_r4 pfam04545
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
 76-115 1.88e-04

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.


Pssm-ID: 461347 [Multi-domain]  Cd Length: 50  Bit Score: 37.02  E-value: 1.88e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 695734550   76 RILRGMSQQEVAEKLGITQSAVSQLEaldsrpqKRTREKL 115
Cdd:pfam04545  16 RYGEGLTLEEIGERLGISRERVRQIE-------KRALRKL 48
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
 76-120 3.67e-04

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 36.50  E-value: 3.67e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 695734550   76 RILRGMSQQEVAEKLGITQSAVSQLEALDSRPQKRTREKLAAIYG 120
Cdd:pfam12844   8 REERGLTQEELAERLGISRSQLSAIENGKSVPPAETLYKIAELLG 52
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
 75-115 3.71e-04

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 36.31  E-value: 3.71e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 695734550  75 WRILRGMSQQEVAEKLGITQSAVSQLEaldsrpqKRTREKL 115
Cdd:cd06171   21 LRFGEGLSYEEIAEILGISRSTVRQRL-------HRALKKL 54
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
 75-116 5.90e-04

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 37.71  E-value: 5.90e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 695734550   75 WRILRGMSQQEVAEKLGITQSAVSQLealdsrpQKRTREKLA 116
Cdd:TIGR02937 121 LRYLEGLSYKEIAEILGISVGTVKRR-------LKRARKKLR 155
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
 71-115 1.23e-03

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 37.52  E-value: 1.23e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 695734550  71 LQAAWRILRGMSQQEVAEKLGITQSAVSQ---------LEALDSRPQKRTREKL 115
Cdd:COG3415   29 LRAVLLLAEGLSVREIAERLGVSRSTVYRwlkryreggLAGLKDRPRGGRPSKL 82
DmsR COG3413
Predicted transcriptional regulator, contains HTH domain [General function prediction only];
79-99 1.83e-03

Predicted transcriptional regulator, contains HTH domain [General function prediction only];


Pssm-ID: 442639 [Multi-domain]  Cd Length: 143  Bit Score: 36.07  E-value: 1.83e-03
                         10        20
                 ....*....|....*....|.
gi 695734550  79 RGMSQQEVAEKLGITQSAVSQ 99
Cdd:COG3413  107 REATLEELAEELGISKSTLSE 127
RodZ COG1426
Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell ...
 71-102 1.86e-03

Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441035 [Multi-domain]  Cd Length: 71  Bit Score: 34.78  E-value: 1.86e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 695734550  71 LQAAwRILRGMSQQEVAEKLGITQSAVSQLEA 102
Cdd:COG1426   10 LRQA-REAKGLSLEDVAERTKISVSYLEAIEE 40
HTH_37 pfam13744
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain.
 79-101 2.01e-03

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain.


Pssm-ID: 433449 [Multi-domain]  Cd Length: 80  Bit Score: 34.89  E-value: 2.01e-03
                          10        20
                  ....*....|....*....|...
gi 695734550   79 RGMSQQEVAEKLGITQSAVSQLE 101
Cdd:pfam13744  30 RGLSQQEAAALLGIAQPKVSALL 52
COG1356 COG1356
Transcriptional regulator [Transcription];
79-116 2.28e-03

Transcriptional regulator [Transcription];


Pssm-ID: 440967 [Multi-domain]  Cd Length: 139  Bit Score: 35.60  E-value: 2.28e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 695734550  79 RGMSQQEVAEKLGITQSAVSQLEaldsrpqKRTREKLA 116
Cdd:COG1356   22 RGLTQQEIADILGTSRANVSSIE-------KSARENIE 52
VapI COG3093
Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense ...
 79-100 2.88e-03

Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense mechanisms];


Pssm-ID: 442327 [Multi-domain]  Cd Length: 87  Bit Score: 34.78  E-value: 2.88e-03
                         10        20
                 ....*....|....*....|..
gi 695734550  79 RGMSQQEVAEKLGITQSAVSQL 100
Cdd:COG3093   21 LGLSQTELAKALGVSRQRISEI 42
FliA COG1191
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA ...
 79-102 3.34e-03

DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA polymerase specialized sigma subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440804 [Multi-domain]  Cd Length: 236  Bit Score: 35.96  E-value: 3.34e-03
                         10        20
                 ....*....|....*....|....
gi 695734550  79 RGMSQQEVAEKLGITQSAVSQLEA 102
Cdd:COG1191  201 EELTLKEIAEVLGVSESRVSRLHK 224
MarR_2 pfam12802
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 73-100 4.18e-03

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 432797 [Multi-domain]  Cd Length: 60  Bit Score: 33.72  E-value: 4.18e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 695734550   73 AAWRILR------GMSQQEVAEKLGITQSAVSQL 100
Cdd:pfam12802   6 AQFRVLLalarnpGLTVAELARRLGISKQTVSRL 39
PRK09637 PRK09637
RNA polymerase sigma factor SigZ; Provisional
 78-115 6.41e-03

RNA polymerase sigma factor SigZ; Provisional


Pssm-ID: 236601 [Multi-domain]  Cd Length: 181  Bit Score: 34.96  E-value: 6.41e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 695734550  78 LRGMSQQEVAEKLGITQSavsqleALDSRPQkRTREKL 115
Cdd:PRK09637 120 LEGLSQKEIAEKLGLSLS------GAKSRVQ-RGRVKL 150
YozG COG3655
DNA-binding transcriptional regulator, XRE family [Transcription];
75-133 6.94e-03

DNA-binding transcriptional regulator, XRE family [Transcription];


Pssm-ID: 442872 [Multi-domain]  Cd Length: 69  Bit Score: 33.19  E-value: 6.94e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 695734550  75 WRIL--RGMSQQEVAEKLGITQSAVSQLEaldSRPQKRTR----EKLAAIYGCKQEQISLYLPKE 133
Cdd:COG3655    7 DELLaeRGMTKKELAEATGISRATLSRLK---NGKAKAVRldtlEKICKALDCQPGDLLEYVPDE 68
HTH_23 pfam13384
Homeodomain-like domain;
71-99 7.84e-03

Homeodomain-like domain;


Pssm-ID: 433164 [Multi-domain]  Cd Length: 50  Bit Score: 32.63  E-value: 7.84e-03
                          10        20
                  ....*....|....*....|....*....
gi 695734550   71 LQAAWRILRGMSQQEVAEKLGITQSAVSQ 99
Cdd:pfam13384   8 ARALLLLAEGLSVKEIAELLGVSRRTVYR 36
tfx PRK03975
putative transcriptional regulator; Provisional
 79-116 8.62e-03

putative transcriptional regulator; Provisional


Pssm-ID: 179690 [Multi-domain]  Cd Length: 141  Bit Score: 34.10  E-value: 8.62e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 695734550  79 RGMSQQEVAEKLGITQSAVSQLEaldsrpqKRTREKLA 116
Cdd:PRK03975  20 RGLTQQEIADILGTSRANVSSIE-------KRARENIE 50
KORA pfam16509
TrfB plasmid transcriptional repressor; KORA is a family of Gram-negative bacterial proteins ...
 70-101 8.71e-03

TrfB plasmid transcriptional repressor; KORA is a family of Gram-negative bacterial proteins that act as global repressors of genes involved in plasmid replication, conjugative transfer and stable inheritance in the IncP group of plasmids. KORA operates as a symmetric dimer, and contacts the DNA via the helix-turn-helix region at the N-terminus.


Pssm-ID: 435386  Cd Length: 84  Bit Score: 33.24  E-value: 8.71e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 695734550   70 SLQAAWRIL-RGMSQQEVAEKLGITQSAVSQLE 101
Cdd:pfam16509  19 TVEIARGVLvEGKRQAEIATELGLTKGAISQAV 51
PRK08215 PRK08215
RNA polymerase sporulation sigma factor SigG;
76-101 9.20e-03

RNA polymerase sporulation sigma factor SigG;


Pssm-ID: 181296 [Multi-domain]  Cd Length: 258  Bit Score: 34.54  E-value: 9.20e-03
                         10        20
                 ....*....|....*....|....*.
gi 695734550  76 RILRGMSQQEVAEKLGITQSAVSQLE 101
Cdd:PRK08215 221 RFFQGKTQMEVAEEIGISQAQVSRLE 246
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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