NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|695770566|ref|WP_032693528|]
View 

MULTISPECIES: TonB-dependent siderophore receptor [Klebsiella]

Protein Classification

TonB-dependent siderophore receptor( domain architecture ID 11486670)

TonB-dependent siderophore receptor acts as a channel to allow import of iron-siderophore complexes, such as Escherichia coli ferrienterobactin receptor, which is involved in the initial step of iron uptake by binding ferrienterobactin

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
1-749 0e+00

FepA family TonB-dependent siderophore receptor;


:

Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 1467.56  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   1 MNNRIKSLALLVNLGIYGAAFPLSAAETASDSKTATADETMVVTAAEQNLQAPGVSTITADEIRKRPPARDVSEIIRTMP 80
Cdd:PRK13524   1 MNKKIHSLALLVNLGIYGVAQAAEAEDAKTDDTPASHEDTIVVTAAEQNLQAPGVSTITAEDIRKRPPANDVSEIIRTMP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  81 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNSVRLGWRGERDTRGDTSWVPPELIERIEVIRGPAAARY 160
Cdd:PRK13524  81 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRYGWRGERDTRGDTNWVPPEMIERIEVLRGPAAARY 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 161 GNGAAGGVVNIITKKSDGEWHGSWNTYMNAPEHKEEGSTKRTNFSLSGPLGGDFSFRLLGNLDKTQADAWDINDGHQSER 240
Cdd:PRK13524 161 GNGAAGGVVNIITKKPTGEWHGSWNTYFNAPEHKAEGATKRTNFSLSGPLGDELSFRLYGNLNKTQADAWDINQGHQSAR 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 241 TGAYANTMPAGREGVKNKNINGVVRWDFAPMQSLEFESGYSRQGNLYAGDTQNTNTNDLVKENYGKETNRLYRQTYSVTW 320
Cdd:PRK13524 241 TGSYAGTLPAGREGVINKDINGLLRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDALVKSLYGKETNRMYRQNYALTH 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 321 NGGWDNGVTTSNWAQYERTRNSRKGEGLAGGTEGIFNSN--QFSDIDLADVMLHSEVNIPLDLVFNQNLTLGSEWNQQRM 398
Cdd:PRK13524 321 RGGWDNGVSTSNYAQYEHTRNSRLPEGLAGGTEGIFNEKatQFSTIDLDDVMLHSEVNLPFDLLVNQTLTLGTEWNQQRM 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 399 KDLASNTQTF-MGGDIDGYDSTGRSPYSKAEIFSLFAEDNVELTDTTMLTPALRFDHHTIVGNNWSPSLNLSQGLWDDFT 477
Cdd:PRK13524 401 KDPSSNTQALtSGGAIPGVSATGRSPYSKAEIFSLFAEDNMELTDSTMLTPGLRFDHHSIVGNNWSPSLNLSQGLGDDFT 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 478 LKMGIARAYKAPSLYQTNPNYILYSKGQGCYASGTgTGCYMMGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRDK 557
Cdd:PRK13524 481 LKMGIARAYKAPNLYQTNPNYILYSKGQGCYASAG-NGCYLQGNDDLKAETSVNKEIGLEFKRDGWLAGLTWFRNDYRNK 559
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 558 IEAGYAPIAHTSKGnvNTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNITYMLQSKNKETGDRLSIIPEYTLNSTLS 637
Cdd:PRK13524 560 IEAGYVPVGTNSVG--KTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNLTYMLQSKNKTTGDPLSIIPEYTLNSTLS 637
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 638 WQIQQDISVQSTFTWYGKQQPKKYNYKGEPAVGSETDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRHWRAGNAQTT 717
Cdd:PRK13524 638 WQATEDLSLQSTFTWYGKQKPKKYNYKGQPVTGSATKEVSPYSIVGLSATYDVTKNVSLTGGVDNLFDKRLWREGNAQTT 717
                        730       740       750
                 ....*....|....*....|....*....|..
gi 695770566 718 GSLtdvsyMAGAGANTYNESGRTWYLGVNTHF 749
Cdd:PRK13524 718 GDL-----IAGAGAYTYNEPGRTYYMSLNTHF 744
 
Name Accession Description Interval E-value
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
1-749 0e+00

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 1467.56  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   1 MNNRIKSLALLVNLGIYGAAFPLSAAETASDSKTATADETMVVTAAEQNLQAPGVSTITADEIRKRPPARDVSEIIRTMP 80
Cdd:PRK13524   1 MNKKIHSLALLVNLGIYGVAQAAEAEDAKTDDTPASHEDTIVVTAAEQNLQAPGVSTITAEDIRKRPPANDVSEIIRTMP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  81 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNSVRLGWRGERDTRGDTSWVPPELIERIEVIRGPAAARY 160
Cdd:PRK13524  81 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRYGWRGERDTRGDTNWVPPEMIERIEVLRGPAAARY 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 161 GNGAAGGVVNIITKKSDGEWHGSWNTYMNAPEHKEEGSTKRTNFSLSGPLGGDFSFRLLGNLDKTQADAWDINDGHQSER 240
Cdd:PRK13524 161 GNGAAGGVVNIITKKPTGEWHGSWNTYFNAPEHKAEGATKRTNFSLSGPLGDELSFRLYGNLNKTQADAWDINQGHQSAR 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 241 TGAYANTMPAGREGVKNKNINGVVRWDFAPMQSLEFESGYSRQGNLYAGDTQNTNTNDLVKENYGKETNRLYRQTYSVTW 320
Cdd:PRK13524 241 TGSYAGTLPAGREGVINKDINGLLRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDALVKSLYGKETNRMYRQNYALTH 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 321 NGGWDNGVTTSNWAQYERTRNSRKGEGLAGGTEGIFNSN--QFSDIDLADVMLHSEVNIPLDLVFNQNLTLGSEWNQQRM 398
Cdd:PRK13524 321 RGGWDNGVSTSNYAQYEHTRNSRLPEGLAGGTEGIFNEKatQFSTIDLDDVMLHSEVNLPFDLLVNQTLTLGTEWNQQRM 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 399 KDLASNTQTF-MGGDIDGYDSTGRSPYSKAEIFSLFAEDNVELTDTTMLTPALRFDHHTIVGNNWSPSLNLSQGLWDDFT 477
Cdd:PRK13524 401 KDPSSNTQALtSGGAIPGVSATGRSPYSKAEIFSLFAEDNMELTDSTMLTPGLRFDHHSIVGNNWSPSLNLSQGLGDDFT 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 478 LKMGIARAYKAPSLYQTNPNYILYSKGQGCYASGTgTGCYMMGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRDK 557
Cdd:PRK13524 481 LKMGIARAYKAPNLYQTNPNYILYSKGQGCYASAG-NGCYLQGNDDLKAETSVNKEIGLEFKRDGWLAGLTWFRNDYRNK 559
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 558 IEAGYAPIAHTSKGnvNTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNITYMLQSKNKETGDRLSIIPEYTLNSTLS 637
Cdd:PRK13524 560 IEAGYVPVGTNSVG--KTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNLTYMLQSKNKTTGDPLSIIPEYTLNSTLS 637
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 638 WQIQQDISVQSTFTWYGKQQPKKYNYKGEPAVGSETDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRHWRAGNAQTT 717
Cdd:PRK13524 638 WQATEDLSLQSTFTWYGKQKPKKYNYKGQPVTGSATKEVSPYSIVGLSATYDVTKNVSLTGGVDNLFDKRLWREGNAQTT 717
                        730       740       750
                 ....*....|....*....|....*....|..
gi 695770566 718 GSLtdvsyMAGAGANTYNESGRTWYLGVNTHF 749
Cdd:PRK13524 718 GDL-----IAGAGAYTYNEPGRTYYMSLNTHF 744
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
54-749 2.35e-130

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 401.06  E-value: 2.35e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  54 GVSTITADEIRKRPpARDVSEIIRTMPGVNLTGNStsgqRGNNRQIDIRGMGPENTLILIDGKPVTSRNSVRlgwrgerd 133
Cdd:cd01347    1 SVSVITAEDIEKQP-ATSLADLLRRIPGVSVTRGG----GGGGSTISIRGFGPDRTLVLVDGLPLASSNYGR-------- 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 134 tRGDTSWVPPELIERIEVIRGPAAARYGNGAAGGVVNIITKKSDGEWHGSWNTYMNAPehkEEGSTKRTNFSLSGPLGGD 213
Cdd:cd01347   68 -GVDLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSD---NSGSSGGGGFDVSGALADD 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 214 --FSFRLLGNLDKTQADAWDINdghqsertgayantmPAGREGVKNKNINGVVRWDFAPMQSLEFESGYSRQGNLYAGDT 291
Cdd:cd01347  144 gaFGARLYGAYRDGDGTIDGDG---------------QADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGT 208
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 292 QNTN-----------TNDLVKENYGKETNRLYRQTYSVTWNGGWDNGvTTSNWAQYERTRNSRKGEGLAGGTEG----IF 356
Cdd:cd01347  209 LPANgtgsslgggpsSNTNGDRDWDYRDRYRKRASLGLEHDLNDTGW-TLRANLSYSYTDNDGDPLILNGGNNAaggdLG 287
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 357 NSNQFSDIDLADVMLHSEVNIPLDLVF-NQNLTLGSEWNQQRmkdlasntqtfmggdidgydstgrspySKAEIFSLFAE 435
Cdd:cd01347  288 RSGYSSERDTTQLGFDAGLNAPFGTGPvAHTLTLGVEYRREE---------------------------LDEKQTALYAQ 340
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 436 DNVELTDTTMLTPALRFDHHTI--------------VGNNWSPSLNLSQGLWDDFTLKMGIARAYKAPSLYQTnpnyily 501
Cdd:cd01347  341 DTIELTDDLTLTLGLRYDHYDQdskdtiaggttakkSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGEL------- 413
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 502 skgqgcYASGTGTGCYMMGNDDLKAETSINKEIGLEFKRD-GWLAGVTWFRNDYRDKIEAgyapiahTSKGNVNTDIYQW 580
Cdd:cd01347  414 ------YGGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGdGLTLSAALFRIDIKNEIVS-------TPTNTGLGLVTVY 480
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 581 ENVPKAVVEGLEGTLNVPVSETVNWTNNITYM----LQSKNKETGDRLSIIPEYTLNSTLSWQI-QQDISVQSTFTWYGK 655
Cdd:cd01347  481 VNGGKARIRGVELEASYDLTDGLGLTGSYTYTdtevKRTDGATTGNRLPGIPKHTANLGLDYELpDEGLTAGGGVRYRGK 560
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 656 QQPKKYNykgepavGSETDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRHWRAGNAqttgsltdvsymAGAGANTYN 735
Cdd:cd01347  561 QYADTAN-------GNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSV------------RGSGLYGYY 621
                        730
                 ....*....|....
gi 695770566 736 ESGRTWYLGVNTHF 749
Cdd:cd01347  622 GPGRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
17-697 1.77e-117

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 366.87  E-value: 1.77e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  17 YGAAFPLSAAETASDSKTATADETMVVTA---AEQNLQAPG-VSTITADEIRKRPpARDVSEIIRTMPGVNLTgnsTSGQ 92
Cdd:COG4771    6 LLLLLALAAQAADALAEDATELEEVVVTAtrtEQSLSDAPAsVSVITAEEIEKLG-ATDLADALRLLPGVSVT---RSGG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  93 RGNNRQIDIRGMGPENTLILIDGKPVTSRNsvrlgwrgeRDTRGDTSWVPPELIERIEVIRGPAAARYGNGAAGGVVNII 172
Cdd:COG4771   82 RGGSSGISIRGLGGDRVLVLIDGVPVNNPA---------LGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINII 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 173 TKKSDGEWHGSWNTYMNAPEHkeegSTKRTNFSLSGPlGGDFSFRLLGNLDKTQADAWDINDGhqsertgayantmPAGR 252
Cdd:COG4771  153 TKKPTDELEGSVSLGYGSNGN----GTYSGSLSLGGP-GDKLSFLLSGSYRDRDGYLDYRNGG-------------FVGN 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 253 EGVKNKNINGVVRWDFAPMQSLEFESGYSRQGNLYAGDtqNTNTNDLVKENYGKETNRLYRQTYSVTWNGGWDNGVTTSn 332
Cdd:COG4771  215 SGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPP--TLGDTEISSDNAGDRDTTTDRGNYSLRYNGDLGDNLDLS- 291
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 333 wAQYERTRNSRKGEGLAGGTegifnsNQFSDIDLADVMLHSEVNIPLDlvFNQNLTLGSEWNQQRMKDlasntqtfmggd 412
Cdd:COG4771  292 -LYYSRTDRDSTNGSLGGST------GSFSDSDDTTYGLELDLTYPLG--GNHTLTLGAEYRYDDLDS------------ 350
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 413 idgyDSTGRSPYSKAEIFSLFAEDNVELTDTTMLTPALRFDHHTIVG----NNWSPSLNLSQGLWDDFTLKMGIARAYKA 488
Cdd:COG4771  351 ----SSFLGGADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAFSPRLGLRYDLSDNLTLRASYGRGFRA 426
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 489 PSLYQTNPNYILYSkgqgcyasgtgtGCYMMGNDDLKAETSINKEIGLEFK--RDGWLAGVTWFRNDYRDKIEAGYAPia 566
Cdd:COG4771  427 PSLAELYGSGTGTP------------GRYVLGNPDLKPETSDNYELGLEYRlgNGGLSLSLTGFYTDIKDLIVLVPVG-- 492
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 567 htskgNVNTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNITYmLQSKNK--ETGDRLSIIPEYTLNSTLSWQIQQDI 644
Cdd:COG4771  493 -----PGPGDVLQYENVGKARTYGLELELKYRLGKGLTLTASYTY-LDSKIDdgDTGEPLPNVPPHKANLGLDYRLPKWW 566
                        650       660       670       680       690
                 ....*....|....*....|....*....|....*....|....*....|...
gi 695770566 645 SVQSTFTWYGKQQPKKYNYkgepavgSETDEVSPYSIVGLSATWDVTKNVSLT 697
Cdd:COG4771  567 LLLLLTRYYGGRYVTPPSG-------RLEGYTPGYTLLDLRASYKLTKNLTLS 612
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
55-749 2.33e-117

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 367.51  E-value: 2.33e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   55 VSTITADEIRKRPpARDVSEIIRTMPGVNLTGNSTSGQRGNnrqIDIRGMGPEntlILIDGkpvTSRNSVRLGWRGerdt 134
Cdd:TIGR01783   6 VSVITRQELEDQQ-AGSLSEALQRVPGVVVGGSGGTTQFGN---ITIRGFGLE---VDIDN---VYLDGVPLLSRG---- 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  135 rgDTSWVPPELIERIEVIRGPAAARYGNGAAGGVVNIITKKSDGEWHGSwntymnAPEHKEEGSTKRTNFSLSGPLGGDF 214
Cdd:TIGR01783  72 --NLAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGS------VTFGAGTRSGYRTAFDLGGPLGADG 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  215 SFRLLGNLDKTQADAWDINDGHQSeRTGAYANTMPAGREGvkNKNINGVVRWDFAPMQSLEFE-----SGYSRQGNLYAG 289
Cdd:TIGR01783 144 TFRGRLNGARQDGDSFYDGAGEET-RLGATATDWQLDDRT--LLRLGAYYQKERDRGGYGGLPasggtSGRDLSSDRYLG 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  290 DTQNTNTNDLVKENYGKETNRLYRQTYSVTWNGGWDNGVTTSNWAQYERTRNSrkgEGLAGGTEGIFNSNQ-FSDIDLAD 368
Cdd:TIGR01783 221 TSSNRNYDDREYLSYGLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASGYSSD---GGLFGRSLTVVNVKQdRVQIDAGL 297
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  369 VMLHSEVNIPLDLVFNQ-NLTLGSEWNQQrMKDLASN----TQTFMGGDIDGYDSTGRSPYSKAEIFSLFAEDNVELTDT 443
Cdd:TIGR01783 298 DGEFETGPIEHDLLLGVsYGQRTTNRFNN-TGYPSDNiyslTATSSARTDIGDSPKDRALSSTTKALNGVALQRILLADK 376
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  444 TMLTPALRFDHHTIVGNNwspSLNLSQGLWDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASGTGTgcymmGNDD 523
Cdd:TIGR01783 377 WTLTLGGRYDSVDVKSNN---GVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGN-----SGDI 448
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  524 LKAETSINKEIGLEFKR-DGWLAGVTWFRNDYRDKIEAGyapiahtSKGN---VNTDIYQWENVPKAVVEGLegTLNVPV 599
Cdd:TIGR01783 449 LEPEKGKNYELGVRYDLgDSLLATAALFRITKDNQLVQD-------PVNGtfsVNAGKTRNRGVELEARGYL--TPGLSL 519
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  600 SETVNWTNNITYMLqSKNKETGDRLSIIPEYTLNSTLSWQIQQDiSVQSTFTWYGKQQPKKYnykgepAVGSETDEVSPY 679
Cdd:TIGR01783 520 SAGYTYTDAEFTED-TNGDTQGNTVPFVPKHTASLWASYAPPVG-DNGLTLGGGVQYTGKAY------VDGGNTGKVPSY 591
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 695770566  680 SIVGLSATWDVT--KNVSLTGGVDNVFDKRHWRAgnaqttgsltdvSYMAGAGANTYNESGRTWYLGVNTHF 749
Cdd:TIGR01783 592 TVVDLSVRYDLTkkKNLTLALNVNNLFDRDYYTS------------GYRWGPSAYIYPGAPRTVGLSVSYDF 651
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
284-746 3.55e-44

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 166.10  E-value: 3.55e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  284 GNLYAGDTQNTNTNDLVKENYGKETNRLYRQTYSVTWNGGWDNGVTTSNWAQYERTR-NSRKGEGLAGGTEGIFNSNQFS 362
Cdd:pfam00593  35 DGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDgDYTSNSSGLSGAGDYLSDDRLY 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  363 DIDLADVMLHSEVNIPLDLVF-NQNLTLGSEWNQQRMKDLASNTQTfmggdidgYDSTGRSPYSKAEIFSLFAEDNVELT 441
Cdd:pfam00593 115 GLYGLDGDLELSLDLSHDLLLgVELRTAGLDYRRLDDDAYDPYDPA--------NPSSSSYSDTTTDSYGLYLQDNIKLT 186
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  442 DTTMLTPALRFDHHTIVGNN--------------WSPSLNLSQGLWDDFTLKMGIARAYKAPSLYQTNPNYilyskgqgc 507
Cdd:pfam00593 187 DRLTLTLGLRYDHYSTDGDDgngggdnfsrsysaFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSG--------- 257
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  508 yaSGTGTGCYMMGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRDKIEAGYAPiahtskGNVNTDIYQWENVPKAV 587
Cdd:pfam00593 258 --SGGGGGAVAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDG------PGLGGTVYTYTNVGKAR 329
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  588 VEGLEGTLNVPVSETVNWTNNITYMLQSKNKE---TGDRLSIIPEYTLNSTLSWQIQQD---ISVQSTFTWYGKQQPKKY 661
Cdd:pfam00593 330 IRGVELELSGRLWGLGLSGGGYTYTDADDDADaddTGNPLPNVPRHTANLGLTYDFPLGgwgARLGARYVGSGERRYGDA 409
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  662 NykgepavgsETDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRHWRAGNAqttgsltdvsymAGAGANTYNESGRTW 741
Cdd:pfam00593 410 A---------NTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSS------------GGGNLGGYPGPGRTF 468

                  ....*
gi 695770566  742 YLGVN 746
Cdd:pfam00593 469 YLGLS 473
 
Name Accession Description Interval E-value
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
1-749 0e+00

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 1467.56  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   1 MNNRIKSLALLVNLGIYGAAFPLSAAETASDSKTATADETMVVTAAEQNLQAPGVSTITADEIRKRPPARDVSEIIRTMP 80
Cdd:PRK13524   1 MNKKIHSLALLVNLGIYGVAQAAEAEDAKTDDTPASHEDTIVVTAAEQNLQAPGVSTITAEDIRKRPPANDVSEIIRTMP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  81 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNSVRLGWRGERDTRGDTSWVPPELIERIEVIRGPAAARY 160
Cdd:PRK13524  81 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRYGWRGERDTRGDTNWVPPEMIERIEVLRGPAAARY 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 161 GNGAAGGVVNIITKKSDGEWHGSWNTYMNAPEHKEEGSTKRTNFSLSGPLGGDFSFRLLGNLDKTQADAWDINDGHQSER 240
Cdd:PRK13524 161 GNGAAGGVVNIITKKPTGEWHGSWNTYFNAPEHKAEGATKRTNFSLSGPLGDELSFRLYGNLNKTQADAWDINQGHQSAR 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 241 TGAYANTMPAGREGVKNKNINGVVRWDFAPMQSLEFESGYSRQGNLYAGDTQNTNTNDLVKENYGKETNRLYRQTYSVTW 320
Cdd:PRK13524 241 TGSYAGTLPAGREGVINKDINGLLRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDALVKSLYGKETNRMYRQNYALTH 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 321 NGGWDNGVTTSNWAQYERTRNSRKGEGLAGGTEGIFNSN--QFSDIDLADVMLHSEVNIPLDLVFNQNLTLGSEWNQQRM 398
Cdd:PRK13524 321 RGGWDNGVSTSNYAQYEHTRNSRLPEGLAGGTEGIFNEKatQFSTIDLDDVMLHSEVNLPFDLLVNQTLTLGTEWNQQRM 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 399 KDLASNTQTF-MGGDIDGYDSTGRSPYSKAEIFSLFAEDNVELTDTTMLTPALRFDHHTIVGNNWSPSLNLSQGLWDDFT 477
Cdd:PRK13524 401 KDPSSNTQALtSGGAIPGVSATGRSPYSKAEIFSLFAEDNMELTDSTMLTPGLRFDHHSIVGNNWSPSLNLSQGLGDDFT 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 478 LKMGIARAYKAPSLYQTNPNYILYSKGQGCYASGTgTGCYMMGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRDK 557
Cdd:PRK13524 481 LKMGIARAYKAPNLYQTNPNYILYSKGQGCYASAG-NGCYLQGNDDLKAETSVNKEIGLEFKRDGWLAGLTWFRNDYRNK 559
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 558 IEAGYAPIAHTSKGnvNTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNITYMLQSKNKETGDRLSIIPEYTLNSTLS 637
Cdd:PRK13524 560 IEAGYVPVGTNSVG--KTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNLTYMLQSKNKTTGDPLSIIPEYTLNSTLS 637
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 638 WQIQQDISVQSTFTWYGKQQPKKYNYKGEPAVGSETDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRHWRAGNAQTT 717
Cdd:PRK13524 638 WQATEDLSLQSTFTWYGKQKPKKYNYKGQPVTGSATKEVSPYSIVGLSATYDVTKNVSLTGGVDNLFDKRLWREGNAQTT 717
                        730       740       750
                 ....*....|....*....|....*....|..
gi 695770566 718 GSLtdvsyMAGAGANTYNESGRTWYLGVNTHF 749
Cdd:PRK13524 718 GDL-----IAGAGAYTYNEPGRTYYMSLNTHF 744
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
4-749 0e+00

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 981.17  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   4 RIKSLALLVNLGIYGAAFPLSAAETASDSKTataDETMVVTAAEQNL-QAPGVSTITADEIRKRPPARDVSEIIRTMPGV 82
Cdd:PRK13528   4 RVNKILWLLTVLLVGLNSPVSAAESSDDDNG---ETMVVEATAEQELkQQPGVSIITAEDIKKRPPVNDLSDIIRKMPGV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  83 NLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNSVRLGWRGERDTRGDTSWVPPELIERIEVIRGPAAARYGN 162
Cdd:PRK13528  81 NLTGNSASGTRGNNRQIDIRGMGPENTLILIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEMVERIEVIRGPAAARYGS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 163 GAAGGVVNIITKKSDGEWHGSWNTYMNAPEHKEEGSTKRTNFSLSGPLGGD-FSFRLLGNLDKTQADAWDINDGHqsert 241
Cdd:PRK13528 161 GAAGGVVNIITKRPTNDWHGSLSLYTNQPESSKEGATRRANFSLSGPLAGDaLTMRLYGNLNKTDADSWDINSSA----- 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 242 gayANTMPAGREGVKNKNINGVVRWDFAPMQSLEFESGYSRQGNLYAGDTQNTNTNDLVKE--NYGKETNRLYRQTYSVT 319
Cdd:PRK13528 236 ---GTKNAAGREGVRNKDINGVLSWKMTPQQILDFEAGYSRQGNIYAGDTQNSNSSAVTESlaKSGKETNRLYRQNYGLT 312
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 320 WNGGWDNGvTTSNWAQYERTRNSRKGEGLAGGTEG-IFNSNQFSDIDLADVMLHSEVNIPLDLVFNQNLTLGSEWNQQRM 398
Cdd:PRK13528 313 HNGIWDWG-QSRLGFYYEKTNNTRMNEGLAGGGEGrITADQTFTTSRLESYRTSGELNVPLNWLFEQTLTVGAEWNRDEL 391
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 399 KDLASNTQTFMGGDIDG--YDSTGRSPYSKAEIFSLFAEDNVELTDTTMLTPALRFDHHTIVGNNWSPSLNLSQGLWDDF 476
Cdd:PRK13528 392 NDPSSTSLTVKDGDIGGisGSAADRSSKNKSEISALYVEDNIEPVPGTNLIPGLRFDYHSEFGSNWSPSLNLSQELGDYF 471
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 477 TLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASGTGTGCYMMGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRD 556
Cdd:PRK13528 472 KVKAGIARAFKAPNLYQSSEGYLLYSRGNGCPKDITSGGCYLVGNKNLDPEISVNKEIGLEFTVDDYHASVTYFRNDYQN 551
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 557 KIEAGYAPIAHTSKGNvntDIYQWENVPKAVVEGLEGTLNVPV-SETVNWTNNITYMLQSKNKETGDRLSIIPEYTLNST 635
Cdd:PRK13528 552 KIVAGDDVIGRTASGA---YILQWQNGGKAVVEGLEGNLLVPLmKDRLNWNTNATYMITSEQKDTGNPLSVIPKYTINST 628
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 636 LSWQIQQDISVQSTFTWYGKQQPKKYN-YKGEPAVGSETDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRHWRAGNa 714
Cdd:PRK13528 629 LDWQITQALSANVNWTLYGKQKPRTHAeSRSEETGGLSGKELGAYSLVGVNVNYDINKNLRLNVGVSNLFDKQIYREGE- 707
                        730       740       750
                 ....*....|....*....|....*....|....*
gi 695770566 715 qttgsltdvsymagaGANTYNESGRTWYLGVNTHF 749
Cdd:PRK13528 708 ---------------GANTYNEPGRAYYAGVTASF 727
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
54-749 2.35e-130

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 401.06  E-value: 2.35e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  54 GVSTITADEIRKRPpARDVSEIIRTMPGVNLTGNStsgqRGNNRQIDIRGMGPENTLILIDGKPVTSRNSVRlgwrgerd 133
Cdd:cd01347    1 SVSVITAEDIEKQP-ATSLADLLRRIPGVSVTRGG----GGGGSTISIRGFGPDRTLVLVDGLPLASSNYGR-------- 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 134 tRGDTSWVPPELIERIEVIRGPAAARYGNGAAGGVVNIITKKSDGEWHGSWNTYMNAPehkEEGSTKRTNFSLSGPLGGD 213
Cdd:cd01347   68 -GVDLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSD---NSGSSGGGGFDVSGALADD 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 214 --FSFRLLGNLDKTQADAWDINdghqsertgayantmPAGREGVKNKNINGVVRWDFAPMQSLEFESGYSRQGNLYAGDT 291
Cdd:cd01347  144 gaFGARLYGAYRDGDGTIDGDG---------------QADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGT 208
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 292 QNTN-----------TNDLVKENYGKETNRLYRQTYSVTWNGGWDNGvTTSNWAQYERTRNSRKGEGLAGGTEG----IF 356
Cdd:cd01347  209 LPANgtgsslgggpsSNTNGDRDWDYRDRYRKRASLGLEHDLNDTGW-TLRANLSYSYTDNDGDPLILNGGNNAaggdLG 287
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 357 NSNQFSDIDLADVMLHSEVNIPLDLVF-NQNLTLGSEWNQQRmkdlasntqtfmggdidgydstgrspySKAEIFSLFAE 435
Cdd:cd01347  288 RSGYSSERDTTQLGFDAGLNAPFGTGPvAHTLTLGVEYRREE---------------------------LDEKQTALYAQ 340
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 436 DNVELTDTTMLTPALRFDHHTI--------------VGNNWSPSLNLSQGLWDDFTLKMGIARAYKAPSLYQTnpnyily 501
Cdd:cd01347  341 DTIELTDDLTLTLGLRYDHYDQdskdtiaggttakkSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGEL------- 413
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 502 skgqgcYASGTGTGCYMMGNDDLKAETSINKEIGLEFKRD-GWLAGVTWFRNDYRDKIEAgyapiahTSKGNVNTDIYQW 580
Cdd:cd01347  414 ------YGGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGdGLTLSAALFRIDIKNEIVS-------TPTNTGLGLVTVY 480
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 581 ENVPKAVVEGLEGTLNVPVSETVNWTNNITYM----LQSKNKETGDRLSIIPEYTLNSTLSWQI-QQDISVQSTFTWYGK 655
Cdd:cd01347  481 VNGGKARIRGVELEASYDLTDGLGLTGSYTYTdtevKRTDGATTGNRLPGIPKHTANLGLDYELpDEGLTAGGGVRYRGK 560
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 656 QQPKKYNykgepavGSETDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRHWRAGNAqttgsltdvsymAGAGANTYN 735
Cdd:cd01347  561 QYADTAN-------GNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSV------------RGSGLYGYY 621
                        730
                 ....*....|....
gi 695770566 736 ESGRTWYLGVNTHF 749
Cdd:cd01347  622 GPGRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
17-697 1.77e-117

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 366.87  E-value: 1.77e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  17 YGAAFPLSAAETASDSKTATADETMVVTA---AEQNLQAPG-VSTITADEIRKRPpARDVSEIIRTMPGVNLTgnsTSGQ 92
Cdd:COG4771    6 LLLLLALAAQAADALAEDATELEEVVVTAtrtEQSLSDAPAsVSVITAEEIEKLG-ATDLADALRLLPGVSVT---RSGG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  93 RGNNRQIDIRGMGPENTLILIDGKPVTSRNsvrlgwrgeRDTRGDTSWVPPELIERIEVIRGPAAARYGNGAAGGVVNII 172
Cdd:COG4771   82 RGGSSGISIRGLGGDRVLVLIDGVPVNNPA---------LGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINII 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 173 TKKSDGEWHGSWNTYMNAPEHkeegSTKRTNFSLSGPlGGDFSFRLLGNLDKTQADAWDINDGhqsertgayantmPAGR 252
Cdd:COG4771  153 TKKPTDELEGSVSLGYGSNGN----GTYSGSLSLGGP-GDKLSFLLSGSYRDRDGYLDYRNGG-------------FVGN 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 253 EGVKNKNINGVVRWDFAPMQSLEFESGYSRQGNLYAGDtqNTNTNDLVKENYGKETNRLYRQTYSVTWNGGWDNGVTTSn 332
Cdd:COG4771  215 SGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPP--TLGDTEISSDNAGDRDTTTDRGNYSLRYNGDLGDNLDLS- 291
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 333 wAQYERTRNSRKGEGLAGGTegifnsNQFSDIDLADVMLHSEVNIPLDlvFNQNLTLGSEWNQQRMKDlasntqtfmggd 412
Cdd:COG4771  292 -LYYSRTDRDSTNGSLGGST------GSFSDSDDTTYGLELDLTYPLG--GNHTLTLGAEYRYDDLDS------------ 350
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 413 idgyDSTGRSPYSKAEIFSLFAEDNVELTDTTMLTPALRFDHHTIVG----NNWSPSLNLSQGLWDDFTLKMGIARAYKA 488
Cdd:COG4771  351 ----SSFLGGADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAFSPRLGLRYDLSDNLTLRASYGRGFRA 426
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 489 PSLYQTNPNYILYSkgqgcyasgtgtGCYMMGNDDLKAETSINKEIGLEFK--RDGWLAGVTWFRNDYRDKIEAGYAPia 566
Cdd:COG4771  427 PSLAELYGSGTGTP------------GRYVLGNPDLKPETSDNYELGLEYRlgNGGLSLSLTGFYTDIKDLIVLVPVG-- 492
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 567 htskgNVNTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNITYmLQSKNK--ETGDRLSIIPEYTLNSTLSWQIQQDI 644
Cdd:COG4771  493 -----PGPGDVLQYENVGKARTYGLELELKYRLGKGLTLTASYTY-LDSKIDdgDTGEPLPNVPPHKANLGLDYRLPKWW 566
                        650       660       670       680       690
                 ....*....|....*....|....*....|....*....|....*....|...
gi 695770566 645 SVQSTFTWYGKQQPKKYNYkgepavgSETDEVSPYSIVGLSATWDVTKNVSLT 697
Cdd:COG4771  567 LLLLLTRYYGGRYVTPPSG-------RLEGYTPGYTLLDLRASYKLTKNLTLS 612
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
55-749 2.33e-117

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 367.51  E-value: 2.33e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   55 VSTITADEIRKRPpARDVSEIIRTMPGVNLTGNSTSGQRGNnrqIDIRGMGPEntlILIDGkpvTSRNSVRLGWRGerdt 134
Cdd:TIGR01783   6 VSVITRQELEDQQ-AGSLSEALQRVPGVVVGGSGGTTQFGN---ITIRGFGLE---VDIDN---VYLDGVPLLSRG---- 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  135 rgDTSWVPPELIERIEVIRGPAAARYGNGAAGGVVNIITKKSDGEWHGSwntymnAPEHKEEGSTKRTNFSLSGPLGGDF 214
Cdd:TIGR01783  72 --NLAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGS------VTFGAGTRSGYRTAFDLGGPLGADG 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  215 SFRLLGNLDKTQADAWDINDGHQSeRTGAYANTMPAGREGvkNKNINGVVRWDFAPMQSLEFE-----SGYSRQGNLYAG 289
Cdd:TIGR01783 144 TFRGRLNGARQDGDSFYDGAGEET-RLGATATDWQLDDRT--LLRLGAYYQKERDRGGYGGLPasggtSGRDLSSDRYLG 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  290 DTQNTNTNDLVKENYGKETNRLYRQTYSVTWNGGWDNGVTTSNWAQYERTRNSrkgEGLAGGTEGIFNSNQ-FSDIDLAD 368
Cdd:TIGR01783 221 TSSNRNYDDREYLSYGLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASGYSSD---GGLFGRSLTVVNVKQdRVQIDAGL 297
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  369 VMLHSEVNIPLDLVFNQ-NLTLGSEWNQQrMKDLASN----TQTFMGGDIDGYDSTGRSPYSKAEIFSLFAEDNVELTDT 443
Cdd:TIGR01783 298 DGEFETGPIEHDLLLGVsYGQRTTNRFNN-TGYPSDNiyslTATSSARTDIGDSPKDRALSSTTKALNGVALQRILLADK 376
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  444 TMLTPALRFDHHTIVGNNwspSLNLSQGLWDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASGTGTgcymmGNDD 523
Cdd:TIGR01783 377 WTLTLGGRYDSVDVKSNN---GVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGN-----SGDI 448
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  524 LKAETSINKEIGLEFKR-DGWLAGVTWFRNDYRDKIEAGyapiahtSKGN---VNTDIYQWENVPKAVVEGLegTLNVPV 599
Cdd:TIGR01783 449 LEPEKGKNYELGVRYDLgDSLLATAALFRITKDNQLVQD-------PVNGtfsVNAGKTRNRGVELEARGYL--TPGLSL 519
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  600 SETVNWTNNITYMLqSKNKETGDRLSIIPEYTLNSTLSWQIQQDiSVQSTFTWYGKQQPKKYnykgepAVGSETDEVSPY 679
Cdd:TIGR01783 520 SAGYTYTDAEFTED-TNGDTQGNTVPFVPKHTASLWASYAPPVG-DNGLTLGGGVQYTGKAY------VDGGNTGKVPSY 591
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 695770566  680 SIVGLSATWDVT--KNVSLTGGVDNVFDKRHWRAgnaqttgsltdvSYMAGAGANTYNESGRTWYLGVNTHF 749
Cdd:TIGR01783 592 TVVDLSVRYDLTkkKNLTLALNVNNLFDRDYYTS------------GYRWGPSAYIYPGAPRTVGLSVSYDF 651
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
5-749 1.23e-104

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 334.93  E-value: 1.23e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   5 IKSLALLVNLGIYGA----AFPLSAAETASDsktatadeTMVVTAA--EQNLQ-APG-VSTITADEIrKRPPARDVSEII 76
Cdd:PRK10064   1 MFRLNPFVRVGLCASaiscAWPVLAVDDDGE--------TMVVTASavEQNLKdAPAsISVITQEDL-QRKPVQNLKDVL 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  77 RTMPGVNLTGNSTsgqrgNNRQIDIRGMGPENTLILIDGKPVTSRNSVRlgwrgeRDTRGDTSWVPPELIERIEVIRGPA 156
Cdd:PRK10064  72 KEVPGVQLTNEGD-----NRKGVSIRGLDSSYTLILIDGKRVNSRNAVF------RHNDFDLNWIPVDAIERIEVVRGPM 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 157 AARYGNGAAGGVVNIITKKSDGEWHGSWNTYMNAPEHKEEGSTKRTNFSLSGPL-GGDFSFRLLGNLDKTQAdawdinDG 235
Cdd:PRK10064 141 SSLYGSDALGGVVNIITKKIGQKWHGTVTVDTTIQEHRDRGDTYNGQFFTSGPLiDGVLGMKAYGSLAKREK------DD 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 236 HQSERTGAYANTMPAgrEGVKNKNINGVVRWdfAPMQSLEFESGysrqgnlYAGDTQNTNTNDLVKenygketNRLYRQT 315
Cdd:PRK10064 215 PQNSTTTDTGETPRI--EGFTSRDGNVEFAW--TPNQNHDFTAG-------YGFDRQDRDSDSLDK-------NRLERQN 276
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 316 YSVTWNGGWDNGvtTSNWAQY-ERTRNSrkgeglaggtegifNSNQFSDIDLADVMLHSEVNIPLDLVfNQNLTLGSEWN 394
Cdd:PRK10064 277 YSLSHNGRWDYG--NSELKYYgEKVENK--------------NPGNSSPITSESNSIDGKYTLPLTAI-NQFLTFGGEWR 339
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 395 QQRMKDLASNTqtfmGGdidGYDSTGRSPYskaeifSLFAEDNVELTDTTMLTPALRFDHHTIVGNNWSPSLNLSQGLWD 474
Cdd:PRK10064 340 HDKLSDAVNLT----GG---TSSKTSASQY------ALFVEDEWRIFEPLALTTGVRMDDHETYGDHWSPRAYLVYNATD 406
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 475 DFTLKMGIARAYKAPSLYQTNPNYILYSkgqgCyasgtGTGCYMMGNDDLKAETSINKEIGLEFK-RDGWLAGV----TW 549
Cdd:PRK10064 407 TVTVKGGWATAFKAPSLLQLSPDWTSNS----C-----RGACKIVGSPDLKPETSESWELGLYYMgEEGWLEGVessvTV 477
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 550 FRNDYRDKIEagyapIAHTSKGNV----------NTD-------IYQWENVPKAVVEGLEGTLNVPVSETVNWTNNITYm 612
Cdd:PRK10064 478 FRNDVDDRIS-----ISRTSDVNAapgyqnfvgfETNgrgrrvpVFRYYNVNKARIQGVETELKIPFNDEWKLSLNYTY- 551
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 613 LQSKNKETGDR--LSIIPEYTLNSTLSWQIQQdiSVQSTFTWYGkqqpkkyNYKGEPAVGSETDEVSP-YSIVGLSATWD 689
Cdd:PRK10064 552 NDGRDVSNGENkpLSDLPFHTANGTLDWKPLA--LEDWSFYVSG-------NYTGQKRADSATAKTPGgYTIWNTGAAWQ 622
                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 690 VTKNVSLTGGVDNVFDKrhwragnaqttgSLTDVSYmagaganTYNESGRTWYLGVNTHF 749
Cdd:PRK10064 623 VTKDVKLRAGVLNLGDK------------DLSRDDY-------SYNEDGRRYFMAVDYRF 663
PRK13483 PRK13483
ligand-gated channel protein;
19-749 3.92e-92

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 301.69  E-value: 3.92e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  19 AAFPLSAAETASDSKTATaDETMVVTAA--EQNLQ-APG-VSTITADEIRKRPpARDVSEIIRTMPGVNLTGNstsgqrG 94
Cdd:PRK13483  15 LPAVFVTHALAQAAPDKT-METVVVTASgyEQQIRdAPAsISVITREDLENRF-YRDLTDALLDVPGVVVTGG------G 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  95 NNRQIDIRGMGPENTLILIDGKPVTSRNSvrlgwRGERDTRG-DTSWVPP-ELIERIEVIRGPAAARYGNGAAGGVVNII 172
Cdd:PRK13483  87 DRTDISLRGMGSQYTLILVDGKRQSSRET-----RPNSDGPGvEQAWTPPlAAIERIEVIRGPMSSLYGSDAIGGVINII 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 173 TKKSDGEWHGSWNTYMNAPEHKEEGSTKRTNFSLSGPLGGD-FSFRLLGNLDKTQADawDINDGHqsertgayantmpag 251
Cdd:PRK13483 162 TRKVPNEWQGEVRLDTTLQENSDSGNVYQANFFVNGPLIKDlLGLQLYGQYTQREED--DIEGGY--------------- 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 252 rEGVKNKNINGVVRWDFAPMQSLEFESGYSRQgnLYAGDTQNTNTNDLVKENYGKE------TNRLYRQTYSVTWNGGWD 325
Cdd:PRK13483 225 -RDKDARSLTAKLALTPNEDHDIMLEVGTSNQ--ERDSTVGKTVAPLAPGESCGRRgcpessTTEYERSTVSLSHTGRWD 301
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 326 NGVTTSnWAQYERTRN-SRKGEglaggtegIFNSNqfsdidladvmLHSEVNIPLDLvfNQNLTLGSEWNQQRMKDLASN 404
Cdd:PRK13483 302 FGTSDT-YIQHEEFDNkSREMK--------IKNTD-----------FQSSLVAPLGQ--EHTLTFGAAYNHQDLTDETSN 359
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 405 TqtfmggdIDGYDSTGRSPYSkaeifsLFAEDNVELTDTTMLTPALRFDHHTIVGNNWSPSLnlsQGLW---DDFTLKMG 481
Cdd:PRK13483 360 Q-------ISDLTDISRTQWA------VFSEDEWRIADDFALTGGLRLDHDENFGGHVSPRV---YGVWnlaPSWTVKGG 423
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 482 IARAYKAPSLYQTNPNYilyskGQgcyASGTGTgcyMMGNDDLKAETSINKEIGLEF-KRDGWLAGVTWFRNDYRDKIEA 560
Cdd:PRK13483 424 VSTGFRAPSLRQTTPDW-----GQ---VSRGGN---IYGNPDLKPETSLNKELGLYYdLGSGLTASLTVFYNEFKDKITR 492
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 561 GYAPIAHTSKG--NVNTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNITYMlQSKNKE---TGDRLSIIPEYTLNST 635
Cdd:PRK13483 493 VACPATQCTDGpnQFGADPTTYVNIDEAVTQGVEASLSYPITSTLSLSGNYTYT-DSEQKSgayKGSPLNQLPKHLFQAS 571
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 636 LSWQIQQDISvqstfTWygkqqpKKYNYKGE---PAVG-SETDEVSP-YSIVGLSATWDVTKNVSLTGGVDNVFDKrhwr 710
Cdd:PRK13483 572 LNWEPTDRLN-----SW------ARVNYRGEesqPTTGpSSSSFIAPsYTFLDLGANYQLTDNLKLSAGIYNLFDK---- 636
                        730       740       750
                 ....*....|....*....|....*....|....*....
gi 695770566 711 agnaqttgsltDVSYMAGAgantYNESGRTWYLGVNTHF 749
Cdd:PRK13483 637 -----------EINYEEYG----YVEDGRRYWLGMTYSF 660
PRK13513 PRK13513
ligand-gated channel protein;
1-707 5.43e-92

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 301.30  E-value: 5.43e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   1 MNNRIKSLALLVNLGIYGAAFplSAAETASdskTATADETMVVTAA--EQNLQ-APG-VSTITADEIRKRPpARDVSEII 76
Cdd:PRK13513   3 QRFRKTHKAALVIAAAISSQA--YAAEKTN---TATPTDTMVVTASgfQQRIQdAPAsISVVTREQLENKA-YRDVTDAL 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  77 RTMPGVNLTGNstsgqrGNNRQIDIRGMGPENTLILIDGKPVTSRNSvrlgwRGERDTRG-DTSWVPP-ELIERIEVIRG 154
Cdd:PRK13513  77 KDVPGVVVTGG------GSTSDISIRGMAAKYTLILVDGKRVDTRST-----RPNSDGSGiEQGWLPPlAAIERIEVVRG 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 155 PAAARYGNGAAGGVVNIITKKSDGEWHGSWNTYMNAPEHKEEGSTKRTNFSLSGPL-GGDFSFRLLGNLDKTQADawDIN 233
Cdd:PRK13513 146 PMSSLYGSDAMGGVINIITRKVQKEWHGSLRADATLQEDSKSGDIFQTNAYASGPLiDGLLGLKVSGLLSHRSED--KII 223
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 234 DGHQSERTGayantmpagregvknkniNGVVRWDFAP--MQSLEFESGYSRQgnlyagdTQNTNTNDLVKENYGKETNRL 311
Cdd:PRK13513 224 DGYNEQRMR------------------NGTATFSLTPddNNEFDFEIGRYVQ-------DRNSTPGRTLALNGTNSDTQY 278
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 312 YRQTYSVTWNGGWDNGVTTSnWAQYERTRNSRKgeglaggtegifnsnqfsDIDLADVMLHSEVNIPLDlvfNQNLTLGS 391
Cdd:PRK13513 279 DRNNYAITHNGYYDFGNSTS-YIQRDETRNPSR------------------QMKSVDTIFNTQTSFLLD---DHTLSLGG 336
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 392 EWNQQRMKDlaSNTQTFMGGDIDGYDStgrspYSKAeifsLFAEDNVELTDTTMLTPALRFDHHTIVGNNWSPSLnlsQG 471
Cdd:PRK13513 337 QYRYEELYD--KGNQLPSASDLNKLTR-----WSWA----LFAEDEWQMTNDFALTGGIRMDQDQNYGTHWTPRL---YG 402
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 472 LW---DDFTLKMGIARAYKAPSLYQTNPNYilyskGQgcyASGTGTGCYMM-GNDDLKAETSINKEIGLEF-KRDGWLAG 546
Cdd:PRK13513 403 VWhlaDQWTLKGGVSTGYRSPDLRQATDNW-----GQ---LTGGGGLPALIlGNSDLKPEKSISQEIGILWdNQENLNAS 474
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 547 VTWFRNDYRDKI-EAGYAPIAHTSK-----GNVNTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNITYMlQSKNKE- 619
Cdd:PRK13513 475 VTLFNTDFKDKItEVRNCDTTNTDGqcvfnGINYDFISDRINVDKANMRGVEATFNWDINQAWSLATNYTFT-QSEQKSg 553
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 620 --TGDRLSIIPEYTLNSTLSWQIQQDISvqstfTWygkqqpKKYNYKGEPAVG---SETDEVSP-YSIVGLSATWDVTKN 693
Cdd:PRK13513 554 afAGQPLNQMPKHMANATLNWQTTEDFA-----TW------IRINYRGKTSEYlnrTSMGSGTPsYTFVDLGASYQLTKE 622
                        730
                 ....*....|....
gi 695770566 694 VSLTGGVDNVFDKR 707
Cdd:PRK13513 623 LRLMGGVYNLLDKR 636
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
39-718 2.69e-76

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 258.99  E-value: 2.69e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  39 ETMVVTA---AEQNLQAPG-VSTITADEIRKRPpARDVSEIIRTMPGVNLTGNStsgqrGNNRQIDIRGMG--PENTLIL 112
Cdd:COG1629    2 EEVVVTAtrtDESLQDVPGsVSVISREQLEDQP-ATDLGDLLRRVPGVSVTSAG-----GGAGQISIRGFGggGNRVLVL 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 113 IDGKPVTSRnsvrlgwrgeRDTRGDTSWVPPELIERIEVIRGPAAARYGNGAAGGVVNIITKKSDGEWHGSWNTYMNApe 192
Cdd:COG1629   76 VDGVPLNDP----------SGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGS-- 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 193 hkeeGSTKRTNFSLSGPlGGDFSFRLlgNLDKTQADAWDINDghqsertgayantmpagreGVKNKNINGVVRWDFAPMQ 272
Cdd:COG1629  144 ----YGTYRASLSLSGG-NGKLAYRL--SASYRDSDGYRDNS-------------------DSDRYNLRAKLGYQLGDDT 197
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 273 SLEFESGYSRQGNLYAGDTQNTNT-------NDLVKENYGKETNRLYRQTYSVTWNGGWDNGVTTSNWAQYERTRNSRKG 345
Cdd:COG1629  198 RLTLSASYSDSDQDSPGYLTLAALrprgamdDGTNPYSNDTDDNTRDRYSLSLEYEHLGDGLKLSASAYYRYDDTDLDSD 277
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 346 EGLAGGTEGIFNSNQFSDIDLAdvmLHSEVNIPLDLVFNQNLTLGSEWNQQRMKdlASNTQTFMGGDIDGYDSTGRSPYS 425
Cdd:COG1629  278 FTPTPADGGTLEQTDFDNRTYG---LELRLTYDLGFGGKHTLLVGLDYQRQDLD--GSGYPLDLGSGSLPTLTSGADDDG 352
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 426 KAEIFSLFAEDNVELTDTTMLTPALRFDHHTIVG----------------NNWSPSLNLSQGLWDDFTLKMGIARAYKAP 489
Cdd:COG1629  353 TTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDVddtvtgtdsasgsrsySAFSPSLGLTYQLSPNLSLYASYSRGFRAP 432
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 490 SLYQTNPNyilyskgqgcyasgtGTGCYMMGNDDLKAETSINKEIGL--EFKRDGWLAGVTWFRNDYRDKIEAGYAPiah 567
Cdd:COG1629  433 TFGELYAN---------------GTDPYSVGNPDLKPETSTNYELGLryRLLDGRLSLSLALFYSDVDNEILSVPLP--- 494
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 568 tskgNVNTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNITYMlQSKNKE--------TGDRLSIIPEYTLNSTLSWQ 639
Cdd:COG1629  495 ----NDSGFSTYYTNAGKARSYGVELELSYQLTPGLSLNASYSYT-DAKFDDdtdgsadlDGNRLPGVPPLTANLGLTYE 569
                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 695770566 640 IQQDISVQSTFTWYGKQQPKKYNYKGEPavgsetdevSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRHWRAGNAQTTG 718
Cdd:COG1629  570 FPGGWSLGLGVRYVGDRYLDDANTQGAP---------GGYTLVDLGAGYRFGDNLTLSLGVDNLFDKKYATSLSVRASN 639
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
23-707 7.06e-73

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 250.69  E-value: 7.06e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  23 LSAAETASDSKtataDETMVVTA---AEQNLQAPG-VSTITADEIRKRPpARDVSEIIRTMPGVNLTGNStsgqrgNNRQ 98
Cdd:PRK13484  19 ISSGYASSDKK----EDTLVVTAsgfTQQLRNAPAsVSVITSEQLQKKP-VSDLVDAVKDVEGISITGGN------EKPD 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  99 IDIRGMGPENTLILIDGKPVTSRNSVRLGWRGErdtrgDTSWVPP-ELIERIEVIRGPAAARYGNGAAGGVVNIITKKSD 177
Cdd:PRK13484  88 ISIRGLSGDYTLILVDGRRQSGRESRPNGSGGF-----EAGFIPPvEAIERIEVIRGPMSSLYGSDAIGGVINIITKPVN 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 178 GE-WHGSWNTYMNAPEHKEEGSTKRTNFSLSGPLGGD-FSFRLLGNLDKTQADawdindghqsertgayanTMPAGREGV 255
Cdd:PRK13484 163 NQtWDGVLGLGGIIQEHGKFGNSTTNDFYLSGPLIKDkLGLQLYGGMNYRKED------------------SISQGTPAK 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 256 KNKNINGVVRWDFAPMQSLEFESGY-SRQGNLYAGDTQN--TNTNDLVKENYGKETNRlYRQTYSVTWNGGWDngVTTSN 332
Cdd:PRK13484 225 DNKNITATLQFTPTESQKFVFEYGKnNQVHTLTPGESLDawTMRGNLKQPNSKRETHN-SRSHWVAAWNAQGE--ILHPE 301
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 333 WAQY-ERTRNSRKGEGLAGGTEgifNSNQFSD--IDLADVMLHSEVNIPLDlvfNQNLTLGSEWNQQRMKDLASNtqtfm 409
Cdd:PRK13484 302 IAVYqEKVIREVKSGKKDKYNH---WDLNYESrkPEITNTIIDAKVTAFLP---ENVLTIGGQFQHAELRDDSAT----- 370
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 410 ggdidGYDSTGRSPYSkAEIFSLFAEDNVELTDTTMLTPALRFDHHTIVGNNWSPSLNLSQGLWDDFTLKMGIARAYKAP 489
Cdd:PRK13484 371 -----GKKTTETQSVS-IKQKAVFIENEYAATDSLALTGGLRLDNHEIYGSYWNPRLYAVYNLTDNLTLKGGIAKAFRAP 444
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 490 SLYQTNPNYilyskgqgcyasGTGT---GCYMMGNDDLKAETSINKEIGLEFKR-DGWLAGVTWFRNDYRDKIeAGYAPI 565
Cdd:PRK13484 445 SIREVSPGF------------GTLTqggASIMYGNRDLKPETSVTEEIGIIYSNdSGFSASATLFNTDFKNKL-TSYDIG 511
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 566 AHTSKGNVNTdiYQWENVPKAVVEGLEGTLNVPVSETVNWTNNITYmLQSKNKETGDRLS----------IIPEYTLNST 635
Cdd:PRK13484 512 TKDPVTGLNT--FIYDNVGEANIRGVELATQIPVYDKWHVSANYTF-TDSRRKSDDESLNgkslkgepleRTPRHAANAK 588
                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 695770566 636 LSWQIQQDISVQSTFTWYGKQ--QPKKYNYKGePAVGSEtdevspYSIVGLSATWDVTKNVSLTGGVDNVFDKR 707
Cdd:PRK13484 589 LEWDYTQDITFYSSLNYTGKQiwAAQRNGAKV-PRVRNG------FTSMDIGLNYQILPDTLINFAVLNVTDRK 655
OM_channels cd01345
Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in ...
462-746 3.23e-72

Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20), which associate as trimers. Maltoporin-like channels have specificities for various sugars and form 18 beta-stranded barrels (18,22), which associate as trimers. Ligand-gated protein channels cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force and they form monomeric, (22,24) barrels. The 150-200 N-terminal residues form a plug that blocks the channel from the periplasmic end.


Pssm-ID: 238655 [Multi-domain]  Cd Length: 253  Bit Score: 235.79  E-value: 3.23e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 462 WSPSLNLSQGLW----DDFTLKMGIARAYKAPSLYQTNPNyilyskgqgcyasgtgtgcymmgNDDLKAETSINKEIGLE 537
Cdd:cd01345    7 FNPVLNIRQGLGqtpdDDLTLK*GYARANKAPSLYQTNPG-----------------------NDDAKAETSDGKEIGLE 63
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 538 FKR-DGWLAGVTWFRNDYRDKIEAGYAPIAHTSKGnvnTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNITYMLQSK 616
Cdd:cd01345   64 FKRdGGWLAGVTYARNDYTNKIEAGYVAVGQNAVG---TDLYQWDNVPKAVVEGLEGSLNVPVSETV*WTNNYTY*LKSE 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 617 NKetGDRLSIIPEYTLNSTLSWQIQQDISVQSTFTWYGKQQPKKYNykgepavgsetdEVSPYSIVGLSATWDVTKNVSL 696
Cdd:cd01345  141 NK--TTRLSIIPEYTLNVTLSWQAREDLS*QVTYTWYKKQQPKKYK------------EIDPYSIVGLSATWDVTKNVSL 206
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 695770566 697 TGGVDNVFDKRHWRAGNAQTTGsltDVSYMAGAGANTYNESGRTWYLGVN 746
Cdd:cd01345  207 TGGYDNLFDKRLWRAGNAQTTG---DANYIAGAGAYTYNEPGDTWY*GVN 253
PRK13486 PRK13486
TonB-dependent receptor;
29-749 2.09e-65

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 230.29  E-value: 2.09e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  29 ASDSKTATADETMVVTAA--EQNLQ--APGVSTITADEIRKRPpARDVSEIIRTMPGVNLtgNSTSGQRGNnRQIDIRGM 104
Cdd:PRK13486  16 FSASSIAAAEDVMIVSASgyEKKLTnaAASVSVISQEELQSSQ-YHDLAEALRSVEGVDV--ESGTGKTGG-LEISIRGM 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 105 GPENTLILIDGkpvtsrnsVRLGWRGERDTRG----DTSWVPP-ELIERIEVIRGPAAARYGNGAAGGVVNIITKKSDGE 179
Cdd:PRK13486  92 PASYTLILIDG--------VRQGGSSDVTPNGfsamNTGFMPPlAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNADK 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 180 WHGSWNTYMNAPEHKEEGSTKRTNFSLSGPL-GGDFSFRLLGNLDKTQADAwdindghQSERTGAYANTMPAGREGvKNK 258
Cdd:PRK13486 164 WLSSVNAGLNLQESNKWGNSSQFNFWSSGPLvDDSVSLQVRGSTQQRQGSS-------VTSLSDTAATRIPYPTES-QNY 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 259 NINGVVRWDFAPMQSLEFESGYSRQgNLYAGDTQNTNTNDLVKENYGKETNRL---YRQTYSV-TWNGGWDNGVTTSNWA 334
Cdd:PRK13486 236 NLGARLDWKASEQDVLWFDMDTTRQ-RYDNRDGQLGSLTGGYDRTLRYERNKIsagYDHTFTFgTWKSYLNWNETENKGR 314
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 335 QYERTRNSRKGEGLAGGTEGIFNSNqfsdidladVMLHSEVNIPLDLvfNQNLTLGSEWNQQRMKD---LASNTQTFmgg 411
Cdd:PRK13486 315 ELVRSVLKRDKWGLAGQPRELKESN---------LILNSLLLTPLGE--SHLVTVGGEFQSSSMKDgvvLASTGETF--- 380
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 412 didgydstgrspysKAEIFSLFAEDNVELTDTTMLTPALRFDHHTIVGNNWSPSLNLSQGLWDDFTLKMGIARAYKAPSL 491
Cdd:PRK13486 381 --------------RQKSWSVFAEDEWHLTDALALTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPRM 446
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 492 YQtnpnyiLYSKGQGcyASGTGTgCYMMGNDDLKAETSINKEIGLEFKR-DGWLAGVTWFRNDYRDKIeagyapIAHTSK 570
Cdd:PRK13486 447 GQ------LHKGISG--VSGQGK-TNLLGNPDLKPEESVSYEAGVYYDNpAGLNANVTGFMTDFSNKI------VSYSIN 511
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 571 GNVNTdiyqWENVPKAVVEGLEGTLNVPV-SETVNWTNNITYMlQSKNKE---TGDRLSIIPEYTLNSTLSWQIQQDISV 646
Cdd:PRK13486 512 DNTNS----YVNSGKARLHGVEFAGTLPLwSEDVTLSLNYTWT-RSEQRDgdnKGAPLSYTPEHMVNAKLNWQITEEVAS 586
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 647 QSTFTWYGKQQPKKYNYKGEPAVGSET-DEVSPY----SIVGLSATWDVTKNVSLTGGVDNVFDKRH-----WRAGNAQT 716
Cdd:PRK13486 587 WLGARYRGKTPRFTQNYSSLSAVQKKVyDEKGEYlkawTVVDAGLSWKMTDALTLNAAVNNLLNKDYsdvslYSAGKSTL 666
                        730       740       750
                 ....*....|....*....|....*....|...
gi 695770566 717 TGSltdVSYMAGAGANTYNESGRTWYLGVNTHF 749
Cdd:PRK13486 667 YAG---DYFQTGSSTTGYVIPERNYWMSLNYQF 696
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
39-718 6.10e-60

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 214.56  E-value: 6.10e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   39 ETMVVTAA--EQNLQ--APGVSTITADEIRKRPPaRDVSEIIRTMPGVNLTGnstsGQRGNNRQIDIRGMGPENTLILID 114
Cdd:TIGR01785   2 DTVTVTATrtRQVLSeaPASVSVISGEQIESKQA-NNLADALNTVPGVDVTG----GGRPPGQSINIRGLQDNRVLVVVD 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  115 GkpvtsrnsVRLGWRGERDTRGDTSWvPPELIERIEVIRGPAAARYGNGAAGGVVNIITKKSDGEWHGSWNTYMNApehk 194
Cdd:TIGR01785  77 G--------ARQNYQRGGAHNGSLFV-DPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAADLLRPGQLFGGLA---- 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  195 eegSTKRTNFSLSGPLGGDFSFRLLGNLDK-TQADAWDINDGHQSERTgayantmPAGREGVKNKNINGVVRWDFAPMQS 273
Cdd:TIGR01785 144 ---KLSYGSNNNSFGGSVAVAGRLDDNLDAlVAATYRDGGNYRNGNKE-------EATNSAYVQKNLLAKLGWQLDDAQR 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  274 LEFESGYsRQGNLYAGDTQNTNTNDLVKENYGKETNRLYRQTYSVTWN-----GGWDNgVTTSNWAQYERTRNSRKGEGL 348
Cdd:TIGR01785 214 LEFSYFT-TEGSLDEAQNSGPGTEYVLGSSSTLLASSTRDRSATLTYNwtpedNPWLD-ATASLYYNRTENDNDRSARGV 291
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  349 aggtegiFNSNQFSDIDL-ADVMLHSEvnipLDLVFNQNLTLGSEWNQQRMKdlasntqtfmgGDIDGYDSTGRSPY--- 424
Cdd:TIGR01785 292 -------GREEGYQYTTYgATLQNTSR----FDVASWSTLTYGVDWMKDKRR-----------TESFDPNSVTTIVPnpp 349
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  425 -SKAEIFSLFAEDNVELTDTTM-LTPALRFDHHTIVGNN-------------WSPSLNLSQGLWDDFTLKMGIARAYKAP 489
Cdd:TIGR01785 350 sAKEYFFGLFLQDNIPLLDDRLtLSAGLRYDHYKLSPKTtadteavdrsysrWSPSLGLSYKPVDWLTLYASYSQGFRAP 429
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  490 SLYQTnpnYILYskgqgcYASGTGTGCYMMGNDDLKAETSINKEIGLEFKRDGWLAG-------VTWFRNDYRDKIEAGY 562
Cdd:TIGR01785 430 SIDEL---YGTG------DHPGTPGGYTFAPNPNLKPETSKTWELGANLSFDNLLLDndqlqfkVAYFYNDVKDFIDLTI 500
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  563 APIAHTSKGNVNtdIYQWENVPKAVVEGLEGTLNVpvsETVNWTNNITYM-LQSKNKETGDRLSIIPEYTLNSTLSWQI- 640
Cdd:TIGR01785 501 GVTDNVTAGMNN--ITQYVNIDGARIRGIEASASY---DAGLWATGLSYGyTIGKDQNTNQWLSNIPPLKLVVTVGYRFp 575
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  641 QQDISVQSTFTWYGKQQPkkyNYKGEPAVGSETDEVSPYSIVGLSATWDVT--KNVSLTGGVDNVFDKRHWRAGNAQTTG 718
Cdd:TIGR01785 576 DRRLDLGAKAAYYERQSE---SPTTEDVAANGLLTTPGYTVVDLYATYQPNavKGLTVRFGVNNLTDRKYTPAQSVPGAG 652
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
39-749 1.94e-58

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 211.12  E-value: 1.94e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   39 ETMVVTAAEQNL--------QAPGVSTITADEIRKRPPaRDVSEIIRTMPGVNLTGnstsGQRGNNRQIDIRGMGPENTL 110
Cdd:TIGR01786   1 DTITVTATRTADpqrrdlsvTPASVSVISREQLKSQQV-RNLRDLLRYEPGVSVVE----GGRGGSQGINIRGLDKNRVA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  111 ILIDGkpvtsrnsVRLGWR--GERDTRGDTSWVPPELIERIEVIRGPAAARYGNGAAGGVVNIITK------KSDGEWHG 182
Cdd:TIGR01786  76 VLVDG--------IRQNTSygGQGSTFYAINSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKdaadllKPGKDLGG 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  183 -SWNTYmnapehkeegSTKRTNFSLSGPLGGdfsfrLLGNLDK-TQADAWDINDGHQSERTGAYANTMPAGREGVKNKNI 260
Cdd:TIGR01786 148 lSKLGY----------SSANNRFTQSVAAAG-----RNDDVDAlVQATYRRGHELKNGNKANIGNESKRSKPNPSDYKSQ 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  261 NGVVR--WDFAPMQSLEF------ESGYSRQGNLYAGDTQNTNTNDLV-KENYGKETNRLYRQTYSVTWNG--GWDNGVT 329
Cdd:TIGR01786 213 SFLAKlgWQLNDAHRLGLsleytqTDYDEPEMTNTSYLTKPLGAPLLSsTVVLGDSKTRDRRTGLDYELNPdnSWLDTVK 292
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  330 TSNWAQYERTRNsRKGEgLAGGTEGIFNSNQFsdIDLADVMLHSEVNIPLDLVFN---QNLTLGSEWNQQRMKDLASNTQ 406
Cdd:TIGR01786 293 LALDKQYIQLYN-YLNA-TSASDYPGVDKNGR--YKDKYDYYTLGFDTNNKIEFSvhsLSLTYGLDRFKDKVSTGDSRRN 368
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  407 TFMGGDIDGYDSTGRSPYsKAEIFSLFAEDNVELTDTTMLTPALRFDHHTIVG---------------NNWSPSLNLSQG 471
Cdd:TIGR01786 369 LPTAAYNLYGYEGENRPV-KGSNFGLFLQDNIKLGDWLSLSAGLRYDHYKTDPkadeskdygaisktySRWSPSLGLTYK 447
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  472 LWDDFTLKMGIARAYKAPSLYQtnpnyiLYskgqGCYASGTGTGCYMMGNDDLKAETSINKEIGLEFKRDgWLAG-VTWF 550
Cdd:TIGR01786 448 PTPWLTLYYSYSQGFRAPSFDE------LY----GTGAHPGGGPYTFLPNPNLKPETSKNWEIGINLHFD-QLDFkVSYF 516
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  551 RNDYRDKIEAGYAPIAHTSKGNV-NTDIYQWENVPKAVVEGLE--GTLNV----PVSETVNWTNNITYMlQSKNKETGDR 623
Cdd:TIGR01786 517 RNDYKDFIDLGIGVTAKGNMAQVgSNTITNYVNIDNARIRGIElsGRYDLgsffSGPDGWTTTLKYGYT-KGKDSDTNPW 595
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  624 LSIIPEYTLNSTLSWQIQQDI-SVQSTFTWYGKQQPKK---YNYKGEPAVGSETDEVSPYSIVGLSATWDVTKNVSLTGG 699
Cdd:TIGR01786 596 LNAITPLKVVLGLGYDHPDEKwGVGLTLTFSGAKDAVDayaTYYENGEAAKAGPLRTPSYTVVDLYGYYKPNKNLTLRFG 675
                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|
gi 695770566  700 VDNVFDKRHWRAGNAqttgsltdvsYMAGAGANTYNESGRTWYLGVNTHF 749
Cdd:TIGR01786 676 VYNLLDRKYTTWESA----------RQAGPLATGYTAPGRNYKASVEYKF 715
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
23-749 3.23e-52

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 192.84  E-value: 3.23e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  23 LSAAETASDSKTATADETMVVTA---AEQNLQA-PG-VSTITADEIRKRPPaRDVSEIIRTMPGVNLTGNSTSGQRGNnr 97
Cdd:COG4772    8 ALLLAAAAAAEAATTLETVVVTGsraAEARLKDvPGsVSVVDREELENQAA-TSLREVLRRVPGVNVQEEDGFGLRPN-- 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  98 qIDIRGMGPE---NTLILIDGKPVTSrnsvrlgwrgerDTRGDTSWV---PPELIERIEVIRGPAAARYGNGAAGGVVNI 171
Cdd:COG4772   85 -IGIRGLGPRrsrGITLLEDGIPIAP------------APYGDPAAYyfpDLERMERIEVLRGAAALRYGPQTVGGAINF 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 172 ITKKSDGEWH-------GSWNTYmnapehkeegstkRTNFSLSGPLgGDFSFRLLGNldKTQADAWdiNDGHQSERTGAY 244
Cdd:COG4772  152 VTRTIPTAFGgelrvtgGSFGYR-------------RTHASVGGTV-GNFGYLVEYS--RKRGDGF--RDNSGFDINDFN 213
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 245 ANtmpagregvknkningvVRWDFAPMQSLEFESGYSRQ-GNLYAGDT---------QNTNTNDlvkeNYGKETNRlYRQ 314
Cdd:COG4772  214 AK-----------------LGYRLSDRQELTLKFQYYDEdANTPGGLTdaqfdadprQSYRPAD----QFDTRRTQ-LSL 271
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 315 TYSVTWNGGWDngVTTSNWAqYERTRNSR-KGEGLAGGTEGIFNSNQFSDIDLADVMLHSEVNIPLDLVFNQnLTLGSEW 393
Cdd:COG4772  272 RYEHQLSDNTT--LTTTAYY-NDFSRNWYiRQNTADPNTPGLGLRGNPRGYRSYGIEPRLTHRFELGGVPHT-LEVGLRY 347
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 394 NQQRMKDLASNTQTFMGGDIDGYDSTGRSPyskAEIFSLFAEDNVELTDTTMLTPALRFDH-------HTIVGNN----- 461
Cdd:COG4772  348 HREEEDRKQYVNTYGQGRSGAGLRRDRRFS---ADALAAYAQNRFELTGRLTLTPGLRYEHirrdrtdRYSTRTGgddsg 424
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 462 ------WSPSLNLSQGLWDDFTLKMGIARAYKAPSLyqtnpnyilyskGQGCYASGtgtgcymmGNDDLKAETSINKEIG 535
Cdd:COG4772  425 snsyseFLPGLGLLYQLTDNLQLYANVSRGFEPPTF------------GDLAYGNG--------GNPDLKPEKSWNYELG 484
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 536 LEFKRDGWLAG-VTWFRNDYRDKIEAGYAPIAHTSkgnvntdiyQWENVPKAVVEGLEGTLNVPVSET----VNWTNNIT 610
Cdd:COG4772  485 TRGRIGNGLSAeVALFYIDYDNELGSCSAAGGDRS---------TFTNAGETRHQGLELALDYDLLKGgglgLPLFAAYT 555
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 611 YmLQSKNKET------GDRLSIIPEYTLNSTLSWQiQQDISVQSTFTWYGKQqpkkY-NYKGEPAVGSeTDEVSPYSIVG 683
Cdd:COG4772  556 Y-TDAEFTSDfgpvfaGNRLPYVPRHQLTAGLGYE-HGGWTANLNGRYVSEQ----FtDAANTVADGS-FGKIPSYTVLD 628
                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 695770566 684 LSATWDVTKNVSLTGGVDNVFDKRHW--RAGNAQTTgsltdvsYMAGAgantynesGRTWYLGVNTHF 749
Cdd:COG4772  629 LSASYDFGKNLSLFAGVNNLFDKRYIasRAPNYAAG-------IRPGP--------PRTVYAGLRLKF 681
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
7-749 1.19e-46

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 177.01  E-value: 1.19e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   7 SLALLVNLGIYGAAFPLSAAETASDSKTATADETMVVTA---AEQNLQAPG-----------------VSTITADEIRKR 66
Cdd:COG4773    1 AAALLAGSGLAAAAAGALAQAAAAAAAEATTLPEVTVTGtaeGTGGYTAKSsstatkldtplretpqsVSVVTRQLIEDQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  67 PpARDVSEIIRTMPGVNLTGNSTSGQRgnnrQIDIRGMGPENtlILIDGKPVTSRNSVRlgwrgerdtrgdtswVPPELI 146
Cdd:COG4773   81 G-ATTLDDALRNVPGVTVSSYDGGGRD----SFSIRGFSIDN--YLRDGLPLGGFGGGQ---------------PDTANL 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 147 ERIEVIRGPAAARYGNGAAGGVVNIITKKSDGEWH-------GSWNTYmnapehkeegstkRTNFSLSGPLG--GDFSFR 217
Cdd:COG4773  139 ERVEVLKGPAGLLYGAGSPGGLVNLVTKRPTAEPQgevslsaGSWDTY-------------RATADVGGPLNedGTLRYR 205
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 218 LlgNLDKTQADAWdindghqsertgayantmpagREGVKNKN--INGVVRWDFAPMQSLEFESGY--SRQGNLYAGDTQN 293
Cdd:COG4773  206 L--NAAYEDGDSF---------------------RDGVDNRRtlIAPSLDWDLTDDTTLTLGAEYqdDDSTGDRGFLPLD 262
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 294 TNTNDL-VKENYGKETNRLYRQTYSVTWNGGW--DNGVTTSNWAQYERTRNSRKGEGLAGGTE--------GIFNSNQFS 362
Cdd:COG4773  263 GTLLDLpRSTNLGEPWDYYDTETTTLFAELEHrfNDDWSLRANARYSDSDRDGRSAYAYGAPDaatgtltrYASARDGDS 342
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 363 DIDLADVMLHSEVNIpldLVFNQNLTLGSEWNQQRMKDLASNTQTF-----MGGDIDGYDSTGRSPYSKAEIFSLFAEDN 437
Cdd:COG4773  343 RSDSLDANLNGKFET---GGLEHTLLVGADYSRYDSDSDSATAGTIniynpVYGNLPEPDFDASDTDTTTRQTGLYAQDQ 419
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 438 VELTDTTMLTPALRFDHHTIVGNNWSPSLNLSQGLwDDFTLKMGIaraykapsLYQTNPN---YILYSKGqgcYASGTGT 514
Cdd:COG4773  420 ISLTDRLSLLLGGRYDWYETDSTNRLGGSTTSYDD-SAFTPRAGL--------VYDLTPGlslYASYSES---FEPQSGA 487
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 515 GcymMGNDDLKAETSINKEIGL--EFKRDGWLAGVTWFRndyrdkIEagyapiahtsKGNVNTDIYQWEN----VPKAVV 588
Cdd:COG4773  488 D---NNGNPLDPETGKQYEAGVkgELFDGRLNATLAVFD------IT----------QKNVATTDPDNPNfyvqVGEVRS 548
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 589 EGLEGTLNVPVSETVNWTNNITYM----LQSKNKETGDRLSIIPEYTLNSTLSWQIQQ----DISVQSTFTWYGKQQpkk 660
Cdd:COG4773  549 RGVELELSGELTPGLNLIAGYTYTdakiTKDADALEGKRLTNVPRHTASLWTTYRFPSgalkGLGLGGGVRYVGERY--- 625
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 661 ynykgepAVGSETDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRHWragnaqtTGSLTDVSYMAGAgantynesGRT 740
Cdd:COG4773  626 -------GDAANTFTLPSYTLVDAGARYDLGKNWTLQLNVNNLFDKKYY-------ASSGSRGYVYYGA--------PRN 683

                 ....*....
gi 695770566 741 WYLGVNTHF 749
Cdd:COG4773  684 VRLSLSYKF 692
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
55-749 1.21e-45

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 173.14  E-value: 1.21e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  55 VSTITADEIRKRPpARDVSEIIRTMPGVnltgnSTSGQRGNNR-QIDIRGMGPENTlILIDGKPVTSRNSVrlgwrgerd 133
Cdd:COG4774   13 VTVVTRELIEDQG-ATSLADALRNVPGV-----TFGAGEGGNGdSFSIRGFSASGD-IYVDGLRDPGQYRR--------- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 134 trgdtswvPPELIERIEVIRGPAAARYGNGAAGGVVNIITKKSDGEWH-------GSWNTYmnapehkeegstkRTNFSL 206
Cdd:COG4774   77 --------DTFNLERVEVLKGPASVLYGRGSPGGVINLVTKRPTDEPFtevtltyGSDGQR-------------RATLDV 135
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 207 SGPLGGDFSFRLlgNLDKTQADAWdindghqsertgayantmpagREGVKNKN--INGVVRWDFAPMQSLEFESGYSRQG 284
Cdd:COG4774  136 NGPLGDDLAYRL--NGMYRDSDSY---------------------RDGVDNDRwgIAPSLTWRLGDRTRLTLDYEYQDDD 192
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 285 NLYAGDTQNTNTNDLVKE----NYGKETNRLYRQTYSVTWNGGWD--NGVTTSNWAQYERT----RNSRKGEGLAGGT-- 352
Cdd:COG4774  193 RTPDYGVPAVANGRPVDVdrstFYGQPDDYSDSETDSATLRLEHDfnDNWTLRNALRYSDYdrdyRNTYPTGGNATGTvt 272
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 353 EGIFNSNQFSDIDLADVMLHSEVNIpldLVFNQNLTLGSEWNQQRMKDLASNTQTFM----------GGDIDGYDSTGRS 422
Cdd:COG4774  273 RSAYRRDQDNDTLSNQTDLTGKFDT---GGVKHTLLAGVEYSREDSDNARYSGGGTAptvnlynpvyGAPVTGPTLGGAD 349
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 423 PYSKAEIFSLFAEDNVELTDTTMLTPALRFDHHTIVGNNWSPSLNLSQGLWDDFTLKMGIaraykapsLYQTNPN---YI 499
Cdd:COG4774  350 NDSRTDTTGLYLQDTISLTDRWSLLAGLRYDRFDTDYTDRTTGATTSSYDDSAFSPRAGL--------VYKPTPNlslYA 421
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 500 LYSKGqgcYASGTGTGCYMMGNDDLKAETSINKEIGL--EFKRDGWLAGVTWFRNDYRDKIEAgyapiahtskGNVNTDI 577
Cdd:COG4774  422 SYSTS---FNPGGGAPSLSNAGQALDPEKSRQYEVGVkwDLLDGRLSLTAALFRIEKTNVRTT----------DPANPGV 488
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 578 YQweNVPKAVVEGLEGTLNVPVSETVNWTNNITYMlQSKNKET------GDRLSIIPEYTLNSTLSWQIQ-QDISVQSTF 650
Cdd:COG4774  489 YV--QTGEQRSRGVELEATGELTPGWSVLAGYTYL-DAEITKSanaanvGNRLPNVPRHSASLWTTYDLPlPGLTLGGGV 565
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 651 TWYGKQQpkkynykgepAVGSETDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRHWRAGNAQTtgsltdvSYMAGAg 730
Cdd:COG4774  566 RYVGSRY----------ADAANTVKLPSYTRFDAGASYRLNKNLTLRLNVNNLTDKRYYASAYGSG-------YVTPGA- 627
                        730
                 ....*....|....*....
gi 695770566 731 antynesGRTWYLGVNTHF 749
Cdd:COG4774  628 -------PRTVLLSASYRF 639
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
284-746 3.55e-44

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 166.10  E-value: 3.55e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  284 GNLYAGDTQNTNTNDLVKENYGKETNRLYRQTYSVTWNGGWDNGVTTSNWAQYERTR-NSRKGEGLAGGTEGIFNSNQFS 362
Cdd:pfam00593  35 DGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDgDYTSNSSGLSGAGDYLSDDRLY 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  363 DIDLADVMLHSEVNIPLDLVF-NQNLTLGSEWNQQRMKDLASNTQTfmggdidgYDSTGRSPYSKAEIFSLFAEDNVELT 441
Cdd:pfam00593 115 GLYGLDGDLELSLDLSHDLLLgVELRTAGLDYRRLDDDAYDPYDPA--------NPSSSSYSDTTTDSYGLYLQDNIKLT 186
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  442 DTTMLTPALRFDHHTIVGNN--------------WSPSLNLSQGLWDDFTLKMGIARAYKAPSLYQTNPNYilyskgqgc 507
Cdd:pfam00593 187 DRLTLTLGLRYDHYSTDGDDgngggdnfsrsysaFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSG--------- 257
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  508 yaSGTGTGCYMMGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRDKIEAGYAPiahtskGNVNTDIYQWENVPKAV 587
Cdd:pfam00593 258 --SGGGGGAVAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDG------PGLGGTVYTYTNVGKAR 329
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  588 VEGLEGTLNVPVSETVNWTNNITYMLQSKNKE---TGDRLSIIPEYTLNSTLSWQIQQD---ISVQSTFTWYGKQQPKKY 661
Cdd:pfam00593 330 IRGVELELSGRLWGLGLSGGGYTYTDADDDADaddTGNPLPNVPRHTANLGLTYDFPLGgwgARLGARYVGSGERRYGDA 409
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  662 NykgepavgsETDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRHWRAGNAqttgsltdvsymAGAGANTYNESGRTW 741
Cdd:pfam00593 410 A---------NTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSS------------GGGNLGGYPGPGRTF 468

                  ....*
gi 695770566  742 YLGVN 746
Cdd:pfam00593 469 YLGLS 473
TonB-B12 TIGR01779
TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane ...
19-749 1.47e-37

TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane receptor found in gamma proteobacteria responsible for translocating the cobalt-containing vitamin B12 (cobalamin). [Transport and binding proteins, Other, Transport and binding proteins, Porins]


Pssm-ID: 273802 [Multi-domain]  Cd Length: 614  Bit Score: 148.86  E-value: 1.47e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   19 AAFPLSAAETASDSKTATADETMVVTA------AEQNLQApgVSTITADEIrKRPPARDVSEIIRTMPGVNLTGNstsGQ 92
Cdd:TIGR01779   9 ALASLLTLCSALHANEAQPLDTVVVTAnrfaqtASQTLAP--VTIITRQDI-ERTQAKSLPELLRRLPGVSIAQN---GG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   93 RGNNRQIDIRGMGPENTLILIDGkpvtsrnsVRLGwrgeRDTRG--DTSWVPPELIERIEVIRGPAAARYGNGAAGGVVN 170
Cdd:TIGR01779  83 RGQNTSLFLRGTESDHVLVLIDG--------IRFG----SAAAGaaDFQQLPVELVERIEYVRGPRSSLYGSEAIGGVIN 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  171 IITKKSDG----EWHGSWNTYmnapehkeegSTKRTNFSLSGPLGGDFSFRLLGNLDKTqadawdinDGHQSERTGAYAN 246
Cdd:TIGR01779 151 IITRRRSGgqgtTLSAGLGSL----------DYQEYSIASGVAIGENGWYSVALGTEST--------KGINVRPGGPGVY 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  247 TmpAGREGVKNKNINGVVRWdfapmqslEFESGYSRQGNLYAGDtqntNTNDLVKENYGketNRLY--RQTYSVTWNGG- 323
Cdd:TIGR01779 213 D--PDRDGFRSDSLLLGGGH--------RFDESWSLFVNALRYE----NRNDYDNYSFG---TRLYkeAEKGDQSFTGGr 275
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  324 ------WDNGVTTSNWAQYERTRNSRKGEGLaggtegifnsnqfsdiDLADVMLHSEVNIPLDLVFNQN--LTLGSEWNQ 395
Cdd:TIGR01779 276 qrqserDVSELTLSTGKSKDWDYAYSKGRYS----------------STSDTREQRNIQWQNDLLVGDGwvLAGGVDWQK 339
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  396 QRMKdlasntqtfmggdidgyDSTGRSPYSKAEIfSLFAEDNVELTDTTmLTPALRFDHHTIVGNNWSPSLNLSQGLWDD 475
Cdd:TIGR01779 340 DSII-----------------SSTADKEDDRSNT-AAFAQVLQQWGQQL-LEASLRRDDNQQFGSHTTGSIAWGYQFIEE 400
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  476 FTLKMGIARAYKAPSLYQT-NPNYilyskgqgcyasgtgtgcymmGNDDLKAETSINKEIGLEfkrdGWLAGVTWFRNDY 554
Cdd:TIGR01779 401 LRFTASYGTAFKAPNLNQLyYPSY---------------------GNPNLQPETSKSAELGFY----GLFSGGKWSISGY 455
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  555 RDKIEAGYAPIAHTSKgnvntdiyQWENVPKAVVEGLEGTLNvpvSETVNWTNNITY-MLQSKNKETGDRLSIIPEYTLN 633
Cdd:TIGR01779 456 RTKINDLIDYDSHPKG--------YPNNIGEARIKGVEATAE---FATGGWTHQLSVdLLDAQNVNTGNTLPRRARQMYK 524
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  634 STLSWQIQQdISVQSTFTWYGKQQPKKYNykgepAVGSETDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRHwragn 713
Cdd:TIGR01779 525 WNADRAFEQ-FDWGASYQYVGKRYDDDYN-----TYPTQNVRLGGYSLLDLRVSYYVTDSWTVQGRIANLFDKDY----- 593
                         730       740       750
                  ....*....|....*....|....*....|....*.
gi 695770566  714 aQTtgsltdvsymagagANTYNESGRTWYLGVNTHF 749
Cdd:TIGR01779 594 -ET--------------AYGYPQAGRAYYLSIRYQF 614
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
41-345 2.30e-36

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 138.08  E-value: 2.30e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  41 MVVTA--AEQNLQAPG--VSTITADEIRKRPpARDVSEIIRTMPGVNLtgnSTSGQRGNNRQIDIRGMGPENTLILIDGK 116
Cdd:COG4206    1 VVVTAtrLEQSKSDLTgsVTVIDAEELERSG-ATSLADALRRVPGVQV---SSSGGPGSAASISIRGLGSNQTLVLIDGV 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 117 PVtsrNSVRLGWRgerdtrgDTSWVPPELIERIEVIRGPAAARYGNGAAGGVVNIITKKSDGEWHGSWNTymnapehkEE 196
Cdd:COG4206   77 PL---NDPSLGGV-------DLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKGSVSA--------SY 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 197 GSTKRTNFSLSGpLGGDFSFRLLGNLDKTQADAWDINDGHQSERTgayantmpagreGVKNKNINGVVRWDFAPMQSLEF 276
Cdd:COG4206  139 GSFGTRRLSASL-SGGAGKFSYSLSASYRRSDGYRYNDPDLRNND------------GYENTSLNARLGYKLGDNGSLSL 205
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 695770566 277 ESGYSRQGNLYAGdTQNTNTNDLVKENYGKETNRLYRQTYSVTWNGGWDNGVTTSNWAQYERTRNSRKG 345
Cdd:COG4206  206 SGGYSDSERGYPG-AVGSDRNLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARAG 273
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
5-718 9.75e-33

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 134.35  E-value: 9.75e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   5 IKSLALLVNLGIygAAFPLSAAETASDsktatadeTMVVTAaeQNLQAPgVSTI-------TADEIrKRPPARDVSEIIR 77
Cdd:PRK10641   2 IKKASLLTALSV--TAFSGWAQDTSPD--------TLVVTA--NRFQQP-VSTVlapttvvTRDDI-DRWQSKSVNDVLR 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  78 TMPGVNLTGNSTSGQRGNnrqIDIRGMGPENTLILIDGKPVTsrnsvRLGWRGErdtrGDTSWVPPELIERIEVIRGPAA 157
Cdd:PRK10641  68 RLPGVDIAQNGGLGQLSS---LFIRGTNSSHVLVLIDGVRLN-----QAGISGS----ADLSQIPISLVQRIEYIRGPRS 135
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 158 ARYGNGAAGGVVNIITKKSD-------GEWHGSWNTYmnapehkeEGSTKRTnfslsgpLGGDFSFRLLGNLDKT----- 225
Cdd:PRK10641 136 AVYGSDAIGGVVNIITTRDKpgttlsaGWGSNGYQNY--------DGSTQQQ-------LGDNTRVTLAGDYTYTkgfdv 200
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 226 QADAwDINDGHQSERTGAYANTMPAGREGVKNKNINGVVRwdfapmqslefESGYSRQGNLYAGDTQNTNTNDLvkenyg 305
Cdd:PRK10641 201 VAYG-NTGTQAQPDRDGFMSKTLWGGLEHQFNDQWSGFVR-----------GYGYDNRTDYDAYYSPGSPLIDT------ 262
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 306 ketnrlyRQTYSVTWNGG--WDNGVTTSNW-AQYERTRN----SRKGEGLAGGTegifnsnqFSDIDLADVMLHSEVnip 378
Cdd:PRK10641 263 -------RQLYSQSWDAGlrYNGGIYSSQLiASYSHSKDynydPHYGRYDSSAT--------LDDMKQYNVQWGNTV--- 324
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 379 ldLVFNQNLTLGSEWNQQRmkdLASNTQTfmggDIDGY--DSTGrspyskaeifsLFAEDNVELTDTTmLTPALRFDHHT 456
Cdd:PRK10641 325 --QVGHGNISAGVDWQKQT---TTPGTGY----VPDGYdqRNTG-----------IYLTGQQQIGDVT-LEGAARSDDNS 383
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 457 IVGnnWSPSLNLSQGlW---DDFTLKMGIARAYKAPSLYQtnpnyiLYSKGqgcyasgtgtgcymmGNDDLKAETSINKE 533
Cdd:PRK10641 384 QFG--WHGTWQTSAG-WefiDGYRFIASYGTAFKAPNLGQ------LYGFY---------------GNPNLKPEESKQWE 439
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 534 IGLEfkrdGWLAGVTWFRNDYRDKIE--AGYAPIAhtskgnvntdiYQWENVPKAVVEGLEGTLNVpvsETVNWTNNITY 611
Cdd:PRK10641 440 GGFE----GLTGPVNWRLSGYRNDIDnlIDYDDHT-----------LKYYNVGKATIKGVEWTGNF---DTGPLTHQVTL 501
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 612 -MLQSKNKETGDRLSIIPEYTLNSTLSWQIqQDISVQSTFTWYGKQQPKKYNykgepAVGSETDEVSPYSIVGLSATWDV 690
Cdd:PRK10641 502 dYVDPRNAITDEPLARRAKQQVKYQLDWQL-YDFDWGVTYQYLGTRYDKDYS-----TYPYQTVKLGGVSLWDLAVSYPV 575
                        730       740
                 ....*....|....*....|....*...
gi 695770566 691 TKNVSLTGGVDNVFDKRHWRAGNAQTTG 718
Cdd:PRK10641 576 TSHLTVRGKIANLFDKDYETVYGYQTAG 603
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
55-168 3.89e-29

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 111.59  E-value: 3.89e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   55 VSTITADEIRKRPpARDVSEIIRTMPGVNltgnSTSGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNsvrlgwrgerDT 134
Cdd:pfam07715   9 VSVVTAEDIEDQG-ATNLADALRGVPGVS----VSSGGGGGGSSISIRGFGSNRVLVLVDGVPLNSGG----------GG 73
                          90       100       110
                  ....*....|....*....|....*....|....
gi 695770566  135 RGDTSWVPPELIERIEVIRGPAAARYGNGAAGGV 168
Cdd:pfam07715  74 SVDLNSIDPEDIERVEVLKGPASALYGSGAIGGV 107
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
55-749 3.47e-12

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 70.06  E-value: 3.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   55 VSTITADEIRKRPpARDVSEIIRTMPGVnltgnSTSGQRGNNRQIDIRGMGPENTLILIDGKPVTSrnsvrlgwrGERDT 134
Cdd:TIGR01782  27 VDVISAEDIGKLP-DVNVAEALQRVPGV-----SIERDQGEGRYVSVRGLGPSYNRTTLNGRTIAS---------TDSGG 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  135 RG-DTSWVPPELIERIEVIRGPAAARYGnGAAGGVVNIITKKSdGEWHGSWNTYMNAPEHKEEGSTKRTNFSLSGPLG-- 211
Cdd:TIGR01782  92 RAfSLDLLPSELVSGVEVYKTPTADMDE-GGIGGTVDLRTRSP-FDYDGRTLSGSAQGGYNDLAGKDKPGPRGAASYSwt 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  212 -GDFSFRLLGNLDKTQADawDINDGHQSERTGAYANTmPAGREGV---------------KNKNINGVVrwDFAPMQSLE 275
Cdd:TIGR01782 170 fGDGQFGVLLSASYQKRD--FAEDNVETENWGTYTSA-DGGAQGLyfprgvryrsyrndrERKGVNGSL--QWRPSDALE 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  276 F------------------------------------ESGYSRQGNLYAGDTQ-----NTNTNDL--------------- 299
Cdd:TIGR01782 245 LyldtlyskydddetrqqiefrtlnggstvitsnqtaTSGALVQGTVANLQILvearyNEEKETTtsltlggewtgdrwt 324
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  300 ------------VKENYGKETNRLYRQTYSVTWNGG------WD-NGVTTSNW--------AQYERTRNSRKGE------ 346
Cdd:TIGR01782 325 ldgdlgyskatrDRPDRVTRFFTAPTPGYDFDYRGGptltlgTPaDGDDASNYtnpangelRRTQISYQKAEDSedaaql 404
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  347 ---------GLAGG----------TEGIFNSNQFSDIDLADV--MLHSEVNIPLDLVFNQNLTLGSEWNQQRmkDLASNT 405
Cdd:TIGR01782 405 datfdgpftSLKFGvryrrrdktnRGSRYRRSIIGATGASGLagVPSDLAGAGLDGGLGGPLTGWDPADLDA--FLNAAR 482
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  406 QTFMGGDIDGYDSTGRSPYSKAE-IFSLFAEDNVELTDTTMLTPALRFDH--HTIVG----------------------- 459
Cdd:TIGR01782 483 GDAAGGGTYTYASTAPNTYTVTEdTTAAYAMANFDTGLRLRGNVGVRYERtdQTSDGwqsqpaangtgsvlvpvsadrdy 562
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  460 NNWSPSLNLSQGLWDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASGTGtgcymmGNDDLKAETSINKEIGLEFK 539
Cdd:TIGR01782 563 TDVLPSLNLAYDLTDDLVLRFAASKTITRPDFGDLAANTSLSDDGTGGTVTVSG------GNPDLKPYESDNLDLSLEWY 636
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  540 -RDGWLAGVTWFRNDyrdkieagyapiahtskgnVNTDIYQWENVPKAVVEGLEGTLNVPVSETVN-------------- 604
Cdd:TIGR01782 637 fGPGGLLSAAVFYKD-------------------IKNFIVTTTSTETNDGGGGLVVAGVLVSRPVNggkagkirgvelgy 697
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  605 ----------WTN-----NITYMLQSKNKETG------DRLSIIPEYTLNSTLSWQ---IQQDISvqstftwygkqqpkk 660
Cdd:TIGR01782 698 qqtfdflpgpLSGfgvqaNYTYVDSEADPSVDgvqrrkLPLPGLSKNTANATLYYEkggFSARLS--------------- 762
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  661 YNYKGEPAVGSETD-------EVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRHWRAGNaqttgsltDVSYMAGagant 733
Cdd:TIGR01782 763 YNYRSDYLLDVGGSninrldrYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTG--------GKQRPRE----- 829
                         890
                  ....*....|....*.
gi 695770566  734 YNESGRTWYLGVNTHF 749
Cdd:TIGR01782 830 YVETGRTYMLGLRYKF 845
PRK09840 PRK09840
catecholate siderophore receptor Fiu; Provisional
4-706 1.59e-11

catecholate siderophore receptor Fiu; Provisional


Pssm-ID: 182105 [Multi-domain]  Cd Length: 761  Bit Score: 67.91  E-value: 1.59e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   4 RIKSLALLVnlgiyGAAFPLSAAETASDSKTAT-ADETMVVTAAEQNLQAPGVS----------------TITADEIRKR 66
Cdd:PRK09840  11 QFHSLAFFA-----GLCIGITPVAQALAAEGQTnADDTLVVEASTPSLYAPDQSadpkfsqpladttqtiTVISEQVIKD 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  67 PPARDVSEIIRTMPGVNL-----TGNSTSGQrgnnrQIDIRGMGPENTlILIDGkpVTSRNSVrlgwrgERDTRGdtswv 141
Cdd:PRK09840  86 QGATNLTEALRNVPGVGTffageNGNTTTGD-----AIYMRGFDTSNS-IYVDG--IRDIGSI------SRDTFN----- 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 142 ppelIERIEVIRGPAAARYGNGAAGGVVNIITKKSdgewhgSWNTYMNAPEHKEEGSTKRTNFSLSGPLGGDFSFRLlgN 221
Cdd:PRK09840 147 ----TEQVEVIKGPSGTDYGRSAPTGSINMISKQP------RNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRL--N 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 222 LDKTQADAwdindghqsertgayantmpAGREGVKNKningvvRWDFAPmqSLEFESG----------YSRQGNLYAG-- 289
Cdd:PRK09840 215 VMGEKTHD--------------------AGRDKVKNE------RYGVAP--SVAFGLGtanrlylnylHVTQNNTPDGgi 266
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 290 -----------DTQNTNTNDLVKEN----YGKETN--RLYRQTYSVTWNGGWDNGVTTSNWAQYERTRNSRKGEGLAGGT 352
Cdd:PRK09840 267 ptiglpgysapSAGRAALNHAGKVDthnfYGTDSDydDSTTDTATMRFEHDINDNTTLRNTTRWSRVKQDYLLTAIMGGA 346
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 353 EGIFNSNQfSDI------------DLADVMLHSEVNIPLDL---VFNQNLTLGSEWNQQRMKDLASNTQTFMGGDI---- 413
Cdd:PRK09840 347 SNITTPTP-SDVntwtwsrtantkDVSNKILTNQTNLTSTFytgSIGHDVSTGVEFTRETQTNYGVNPVTLPAVNLyhpd 425
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 414 -----DGYDSTGRSPYSKAEIFSLFAEDNVELTDTTMLTPALRFDH-HT---------------IVGNNWSPSLNLsqgL 472
Cdd:PRK09840 426 ssihpGGLTRNGANANGQTDTFAIYAFDTLQLTRDWELNGGIRLDNyHTeydsatacggsgrgaITCPAGVAKGSP---V 502
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 473 WDDFTLKMGIARAYKAPSLYQTNPN---YILYSKGQ--------GCYASGTGTGCYMMGNDDLKAETSinkEIGLEF--- 538
Cdd:PRK09840 503 TTVDTAKSGNLVNWKAGALYKLTENgnvYINYAVSQqppggsnfALAQSGSGNSANRTDFKPQKANTS---EIGTKWqvl 579
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 539 -KRDGWLAGVtwFRNDYRDKIEAgyapiahtskgnvnTDIYQWENVPKAVVEGLEgtLNVPVSETVNWTNNITYMLQSKN 617
Cdd:PRK09840 580 dKRLLLTAAL--FRTDIENEVEQ--------------NDDGTYSQYGKKRVEGYE--LSVAGNITPAWQVIAGYTQQKAT 641
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 618 KETG--------DRLSIIPEYTLNSTLSWQIQQDISVQSTFTWYGKQQPKKynykgEPAVGSeTDEVSPYSIVGLSATWD 689
Cdd:PRK09840 642 VKNGkdvaqdgsSSLPYTPEHAFTLWSQYQATDDLSVGGGARYIGSMHRGS-----DGAVGT-PAFTEGYWVADAKLGYR 715
                        810
                 ....*....|....*..
gi 695770566 690 VTKNVSLTGGVDNVFDK 706
Cdd:PRK09840 716 VNRNLDLQLNVYNLFDT 732
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
55-618 1.30e-08

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 58.37  E-value: 1.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   55 VSTITADEIRKRPpardVSEIIRT----MPGVNLTgnSTSGQRGNNRQIDIRGM----GPENTLILIDGKPVTSrnsvrl 126
Cdd:TIGR04056  98 VSTVKAKELKKVP----VSNLSNAlqgkVAGVIIT--QSSGEPGGDAEIWIRGIssfgGNNSPLYVIDGVPRDN------ 165
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  127 gwrgerdtrgDTSWVPPELIERIEVIRGPAA-ARYGNGAAGGVVNIITKKS---------DGEWHGSWNT----YMNAPE 192
Cdd:TIGR04056 166 ----------GLSDLNPEDIESISVLKDASAtAIYGSRGANGVILITTKRGkegkpkisyNAEFGFSTPTrlpeMLNAYE 235
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  193 ----HKEEGSTK------------------------------------------RTNFSLSGplGGD------------- 213
Cdd:TIGR04056 236 yaelYNEALLNRgssppdiytdeeieayrngldpdlypntdwqdeifkrtafnqRHNLSVSG--GTEkaryyvslgyyne 313
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  214 -----------FSFRLlgNLD-----KTQADAwDINdGHQSERTGAYANTMpagregvknkNINGVVRwDFAPMQSLEFE 277
Cdd:TIGR04056 314 egilknsdykrYNFRA--NIDakltkTLKLSL-NVS-GSLSKYNNPGGSTS----------NIWGALM-LFPRGTPYSTP 378
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  278 SGYSRQGNLYAGDTQNTNTNDLVKENYGKETNRLYR--QTYSVTWN----------GGWDNgVTTSNWAQYERTRNSRKG 345
Cdd:TIGR04056 379 PVYSDGYYPAYNSGNTSLQNPYALLNRGYNENERNRlnGNASLEQKitkglklkgtFSYDY-SNYKNKKYYKNPYYYNAT 457
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  346 EGLAGGTEGIFNSNQFSdidladvmLHSEVNIPLDLVFNQ---NLTLGSEWNQQRMKDLASNTQTFMGGDIDGYDSTGRS 422
Cdd:TIGR04056 458 GGANNGYYSESNSRSRN--------YYLEATLNYNRTFGKhnvSALLGYSQQENKSSSYGGLLDDLPSLDAGTSDASVSG 529
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  423 PYSKAEIFSLFAEDNVELTDTTMLTPALR------FDHHTIVGNNWSPSL--NLSQGLW--------DDFTLKMGIARA- 485
Cdd:TIGR04056 530 SDSEYRLQSLFGRATYSYKDRYLLEFNFRydgssrFAKGNRWGFFPSVSLgwRISEEKFmkklkkwlSFLKLRASYGIVg 609
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  486 -----YKAPSLYQTNPNYILYSKGQGCYASGTGTGCYMMGNDDLKAETSINKEIGLEFK--RDGWLAGVTWFRNDYRDKI 558
Cdd:TIGR04056 610 ndnigDRYPYLSLYNLGDGGYNFGTNNGTSVTGITESRYGNPNLKWEKTKKWNLGLDLGffNNRLSLTVDYYYKKTKDIL 689
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 695770566  559 EAgyAPIAHTSKGNvntdiYQWENVPKAVVEGLEGTLNVPVSETVNWT----NNITYmlqSKNK 618
Cdd:TIGR04056 690 QS--RSLPSVTGYS-----SPYANIGKVKNKGVELSLNYRNKIGKDFSwsvrGNFTY---NKNK 743
PRK14050 PRK14050
TonB-dependent siderophore receptor;
25-179 4.20e-08

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 56.73  E-value: 4.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  25 AAETASDSKTATAdetmvVTAAEQNlqapgVSTITADEIRKRPPARDVSEIIRTMPGVnltgnsTSGQRGNNRQID---I 101
Cdd:PRK14050  63 AKATATGSKTDTP-----ITEIPQS-----VSVVGRQEMDDRGVTNKVDEALRYTPGV------LSQPFGTDGDTDwfyI 126
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 695770566 102 RGMGPENTLILIDGKPVTSrnsvrLGWRGERdtrgdtswVPPELIERIEVIRGPAAARYGNGAAGGVVNIITKKSDGE 179
Cdd:PRK14050 127 RGFDATQTGVFLDGLNLFS-----YGFGGFQ--------IDPFMLERVEVLKGPASVLYGGSNPGGIVNMVSKRPLDE 191
PRK10044 PRK10044
ferrichrome outer membrane transporter; Provisional
2-220 4.32e-08

ferrichrome outer membrane transporter; Provisional


Pssm-ID: 236643 [Multi-domain]  Cd Length: 727  Bit Score: 56.69  E-value: 4.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566   2 NNRIKSLALLVNLGIYGAAFPLSAAETAsdsktatADETMVVTAA-----------------------------EQNLQA 52
Cdd:PRK10044  10 NHSLRKIAVVVATAVSGMSVYAQAAVEP-------KEETITVTAApapqesawgpaatiaakrsatgtktdtpiEKTPQS 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  53 pgVSTITADEIRKRPPArDVSEIIRTMPGVnltgnsTSGQRGNNRQID---IRGMGPENTlilidgkpvtSRNSVRLGWR 129
Cdd:PRK10044  83 --ISVVTAEEMALHQPK-SVKEALSYTPGV------SVGTRGASNTYDhliIRGFAASGQ----------SQNNYLDGLK 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 130 GERDTRGDTSwVPPELIERIEVIRGPAAARYGNGAAGGVVNIITKKSDGE-------WHGSWNTYmnapehkeegstkRT 202
Cdd:PRK10044 144 LQGNFYNDAV-IDPYMLERAELMRGPVSVLYGKSNPGGLLNMVSKRPTTEplkevqfKMGTDNLF-------------QT 209
                        250       260
                 ....*....|....*....|
gi 695770566 203 NFSLSGPL--GGDFSFRLLG 220
Cdd:PRK10044 210 GFDFSDALddDGVYSYRLTG 229
PRK14049 PRK14049
ferrioxamine B receptor precursor protein; Provisional
50-220 5.91e-05

ferrioxamine B receptor precursor protein; Provisional


Pssm-ID: 172541 [Multi-domain]  Cd Length: 726  Bit Score: 46.43  E-value: 5.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  50 LQAP-GVSTITADEIRKRPPaRDVSEIIRTMPGVNltgnstsgqrgnnrqIDIRGMGPENTLILIDGKPVTSRNSVRlgw 128
Cdd:PRK14049  77 LETPqSISSVTEQQLKDRNP-QTLLETLAYTPGAR---------------VGAFGFDPRFDAFFVRGFDVTYTGVFR--- 137
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566 129 RGERDTRGDTSW--VPPELIERIEVIRGPAAARYGNGAAGGVVNIITKKSDGEwhgswntymnaPEHKEE---GSTKR-- 201
Cdd:PRK14049 138 DNLRQPGASSSIfkTEPYGLEGVSILRGPSSALYGASGAGGLFNLITKRPTEE-----------PLREVQvqyGTNNRyq 206
                        170       180
                 ....*....|....*....|.
gi 695770566 202 TNFSLSGPL--GGDFSFRLLG 220
Cdd:PRK14049 207 GQFDFSGPVneTDPVYYRLTG 227
OMP_b-brl_3 pfam14905
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ...
460-746 1.37e-03

Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.


Pssm-ID: 434300 [Multi-domain]  Cd Length: 407  Bit Score: 41.88  E-value: 1.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  460 NNWSPSLNLSQGLWDD--FTLKMGIARAYKAPSLYQTNPNYILYSKGQgcyasgtgtgcYMMGNDDLKAETSINKEIGLE 537
Cdd:pfam14905 157 FNLFPSASLSYKLNDNnsLQLSLYYRRIINRPSYWDLNPFRNYSDPYN-----------YSQGNPNLKPEYTNSFELGYT 225
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  538 FKrdgWLAGVTWFRNDYRDKIEAGYapiahTSKGNVNTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNIT-YMLQSK 616
Cdd:pfam14905 226 YK---WKLSLSLSYRYTNDVIQQTF-----ITDDNDNVTYTTYENLGKSNSYGLELSASFNPTKWWSLNGNLNgYYNKYK 297
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695770566  617 NKETGDRLSIIPEYTLNSTLSWQIQQDISVQSTFTWYGKQqpkkYNYKGepavgsetdEVSPYSIVGLSATWDVTKN-VS 695
Cdd:pfam14905 298 IDGSLNSDFSNFGFNWNLNNTFTLPKGWSLQLNGNYRSPR----VTGQG---------KIKPFYSLDLGLSKSFLKKkLT 364
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 695770566  696 LTGGVDNVFDKRHWRagnAQTTGSLTDVSYMagagaNTYNESgRTWYLGVN 746
Cdd:pfam14905 365 LSLNVNDIFNTRKFR---STTNYDNGFIQSY-----NNKWDS-RSVRLSLS 406
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH