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Conserved domains on  [gi|704419207|ref|WP_033469864|]
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amino acid ABC transporter permease [Bordetella bronchiseptica]

Protein Classification

amino acid ABC transporter permease( domain architecture ID 11468467)

amino acid ABC transporter permease such as Rhizobium leguminosarum general L-amino acid transport system permease protein AapQ, which is part of a binding-protein-dependent transport system for L-amino acids and affects the uptake as well as efflux of these amino acids

Gene Ontology:  GO:0043190|GO:0140359|GO:0042626|GO:0016020|GO:0006865
PubMed:  25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BatB COG4597
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 11-403 1.10e-176

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 443651 [Multi-domain]  Cd Length: 397  Bit Score: 497.75  E-value: 1.10e-176
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207  11 PDKRAARPLLSRLHDRKVRGVLLQLLLAALLLWLGYVGVSNAVANLKAANIASGFGFLASTAGFDINQSLIPYSgATSTY 90
Cdd:COG4597    6 DPPPPSPRLSSLLYDPRVRSILFQVLALALVVALVWYLVSNTLANLAARGIATGFGFLDRTAGFDISQSLIPYS-PTDTY 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207  91 GDAFVVGLLNTLLVAAIGIVLATLIGFLVGIARLSSNVVVAAVATLYVETLRNLPLLLQIFFWYSAVLVALPAARESLHL 170
Cdd:COG4597   85 GRAFLVGLLNTLLVAVLGIVLATILGFLVGIARLSSNWLVSKLATVYVEIFRNIPLLLQIFFWYFAVLEALPSPRQSLSL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 171 ADWVFLNNRGLYLPFVNIDGPAWPLWLALALAVLGYALARRLALRARLRGGRSYPARTMALGLFVVVLGGGLLAVDPAAS 250
Cdd:COG4597  165 FDGVFLNNRGLYLPAPVFEPGFGWVLAALLAAIVAAFVLRRWARRRQEATGQRFPVWWISLALLVGLPLLAFLLLGAPLS 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 251 LDLPRFRGFGFAGGLRIYPEMVALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIP 330
Cdd:COG4597  245 LDYPELKGFNFRGGLTLSPEFVALLLALSLYTAAFIAEIVRAGIQAVSKGQTEAARALGLRPGQTLRLVVLPQALRVIIP 324

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 704419207 331 PLTSQFLNLTKNSSLAVAIAYPDLVQVFMGTVLNQTGRAVEIVSITMAVYLAISLVTSALMGVYNRRVRLVER 403
Cdd:COG4597  325 PLTSQYLNLTKNSSLAVAIGYPDLVSVFAGTTLNQTGQAIEIIAITMAVYLTISLLISLLMNWYNRRVALVER 397
 
Name Accession Description Interval E-value
BatB COG4597
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 11-403 1.10e-176

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443651 [Multi-domain]  Cd Length: 397  Bit Score: 497.75  E-value: 1.10e-176
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207  11 PDKRAARPLLSRLHDRKVRGVLLQLLLAALLLWLGYVGVSNAVANLKAANIASGFGFLASTAGFDINQSLIPYSgATSTY 90
Cdd:COG4597    6 DPPPPSPRLSSLLYDPRVRSILFQVLALALVVALVWYLVSNTLANLAARGIATGFGFLDRTAGFDISQSLIPYS-PTDTY 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207  91 GDAFVVGLLNTLLVAAIGIVLATLIGFLVGIARLSSNVVVAAVATLYVETLRNLPLLLQIFFWYSAVLVALPAARESLHL 170
Cdd:COG4597   85 GRAFLVGLLNTLLVAVLGIVLATILGFLVGIARLSSNWLVSKLATVYVEIFRNIPLLLQIFFWYFAVLEALPSPRQSLSL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 171 ADWVFLNNRGLYLPFVNIDGPAWPLWLALALAVLGYALARRLALRARLRGGRSYPARTMALGLFVVVLGGGLLAVDPAAS 250
Cdd:COG4597  165 FDGVFLNNRGLYLPAPVFEPGFGWVLAALLAAIVAAFVLRRWARRRQEATGQRFPVWWISLALLVGLPLLAFLLLGAPLS 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 251 LDLPRFRGFGFAGGLRIYPEMVALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIP 330
Cdd:COG4597  245 LDYPELKGFNFRGGLTLSPEFVALLLALSLYTAAFIAEIVRAGIQAVSKGQTEAARALGLRPGQTLRLVVLPQALRVIIP 324

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 704419207 331 PLTSQFLNLTKNSSLAVAIAYPDLVQVFMGTVLNQTGRAVEIVSITMAVYLAISLVTSALMGVYNRRVRLVER 403
Cdd:COG4597  325 PLTSQYLNLTKNSSLAVAIGYPDLVSVFAGTTLNQTGQAIEIIAITMAVYLTISLLISLLMNWYNRRVALVER 397
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 264-401 4.57e-17

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 79.33  E-value: 4.57e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 264 GLRIYPeMVALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIPPLTSQFLNLTKNS 343
Cdd:PRK09494  84 DLRIDP-FTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRRETLRYVIGPLALRRMLPPLGNQWIISIKDT 162

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 704419207 344 SLAVAIAYPDLV---QVFMGTVLnqtgRAVEIVSITMAVYLAISLVTSALMGVYNRRVRLV 401
Cdd:PRK09494 163 SLFIVIGVAELTrqgQEIIAGNF----RALEIWSAVAVIYLIITLVLSFILRRLERRMKIL 219
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 269-397 7.60e-13

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 67.19  E-value: 7.60e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207  269 PEMVALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIPPLTSQFLNLTKNSSLAVA 348
Cdd:TIGR03003  84 PALVAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLVAMFKETPVLSA 163

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 704419207  349 IAYPDLVQVfMGTVLNQTGRAVEIVSITMAVYLAISLVTSALMGVYNRR 397
Cdd:TIGR03003 164 ITVLELMNQ-AKSIGNSTFRYLEPMTLVGVFFLILSIISVFFLRRLEAR 211
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 271-399 1.73e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 48.06  E-value: 1.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207  271 MVALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIPPLTSQFLNLTKNSSLAVAI- 349
Cdd:pfam00528  52 ILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLg 131

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 704419207  350 AYPDLVQVFMGTVLN-QTGRAVEIVSITMAVYLAISLVTSALMGVYNRRVR 399
Cdd:pfam00528 132 SWPGLGLLLIEAILGyDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 273-387 3.52e-06

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 47.27  E-value: 3.52e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 273 ALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIPPLTSQFLNLTKNSSLAVAIAYP 352
Cdd:cd06261   75 PALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGG 154

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 704419207 353 DLVQVFMGTVLNQTGRAVEIVSITMAVYLAISLVT 387
Cdd:cd06261  155 EAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
 
Name Accession Description Interval E-value
BatB COG4597
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 11-403 1.10e-176

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443651 [Multi-domain]  Cd Length: 397  Bit Score: 497.75  E-value: 1.10e-176
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207  11 PDKRAARPLLSRLHDRKVRGVLLQLLLAALLLWLGYVGVSNAVANLKAANIASGFGFLASTAGFDINQSLIPYSgATSTY 90
Cdd:COG4597    6 DPPPPSPRLSSLLYDPRVRSILFQVLALALVVALVWYLVSNTLANLAARGIATGFGFLDRTAGFDISQSLIPYS-PTDTY 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207  91 GDAFVVGLLNTLLVAAIGIVLATLIGFLVGIARLSSNVVVAAVATLYVETLRNLPLLLQIFFWYSAVLVALPAARESLHL 170
Cdd:COG4597   85 GRAFLVGLLNTLLVAVLGIVLATILGFLVGIARLSSNWLVSKLATVYVEIFRNIPLLLQIFFWYFAVLEALPSPRQSLSL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 171 ADWVFLNNRGLYLPFVNIDGPAWPLWLALALAVLGYALARRLALRARLRGGRSYPARTMALGLFVVVLGGGLLAVDPAAS 250
Cdd:COG4597  165 FDGVFLNNRGLYLPAPVFEPGFGWVLAALLAAIVAAFVLRRWARRRQEATGQRFPVWWISLALLVGLPLLAFLLLGAPLS 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 251 LDLPRFRGFGFAGGLRIYPEMVALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIP 330
Cdd:COG4597  245 LDYPELKGFNFRGGLTLSPEFVALLLALSLYTAAFIAEIVRAGIQAVSKGQTEAARALGLRPGQTLRLVVLPQALRVIIP 324

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 704419207 331 PLTSQFLNLTKNSSLAVAIAYPDLVQVFMGTVLNQTGRAVEIVSITMAVYLAISLVTSALMGVYNRRVRLVER 403
Cdd:COG4597  325 PLTSQYLNLTKNSSLAVAIGYPDLVSVFAGTTLNQTGQAIEIIAITMAVYLTISLLISLLMNWYNRRVALVER 397
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 89-399 8.60e-47

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 159.47  E-value: 8.60e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207  89 TYGDAFVVGLLNTLLVAAIGIVLATLIGFLVGIARLSSNVVVAAVATLYVETLRNLPLLLQIFFWYSAVlvalpaaresl 168
Cdd:COG0765   10 DYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGL----------- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 169 hladwvflnnrglylpfvnidgpawplwlalalavlgyalarrlalrarlrggrsypartmalglfvvvlgggllavdPA 248
Cdd:COG0765   79 ------------------------------------------------------------------------------PL 80

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 249 ASLDLPRFrgfgfagglriypemVALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVI 328
Cdd:COG0765   81 LGIDLSPF---------------VAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRII 145

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 704419207 329 IPPLTSQFLNLTKNSSLAVAIAYPDLVQVfMGTVLNQTGRAVEIVSITMAVYLAISLVTSALMGVYNRRVR 399
Cdd:COG0765  146 LPPLGNEFISLLKDTSLVSVIGVPELTRA-AQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRLA 215
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 90-398 6.19e-18

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 82.06  E-value: 6.19e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207  90 YGDAFVVGLLNTLLVAAIGIVLATLIGFLVGIARLSSNVVVAAVATLYVETLRNLPLLLQIFFWYSAvLVALPAARESLH 169
Cdd:COG4160    9 YLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYYG-LGQFEWVRESWL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 170 ladWVFLNNrglylPFvnidgpawplwlalalavlgyalarrlalrarlrggrsYPArtmalglfvvvlgggllavdpaa 249
Cdd:COG4160   88 ---WPLLRD-----PW--------------------------------------FCA----------------------- 98

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 250 sldlprfrgfgfagglriypemvalVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVII 329
Cdd:COG4160   99 -------------------------LLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILPSALRRAL 153

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 704419207 330 PPLTSQFLNLTKNSSLAVAIAYPDLvqvfMG---TVLNQTGRAVEIVSITMAVYLAISLVTSALMGVYNRRV 398
Cdd:COG4160  154 PAYSNEVILMLKATALASTITVMDL----TGvarRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRL 221
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 264-401 4.57e-17

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 79.33  E-value: 4.57e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 264 GLRIYPeMVALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIPPLTSQFLNLTKNS 343
Cdd:PRK09494  84 DLRIDP-FTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRRETLRYVIGPLALRRMLPPLGNQWIISIKDT 162

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 704419207 344 SLAVAIAYPDLV---QVFMGTVLnqtgRAVEIVSITMAVYLAISLVTSALMGVYNRRVRLV 401
Cdd:PRK09494 163 SLFIVIGVAELTrqgQEIIAGNF----RALEIWSAVAVIYLIITLVLSFILRRLERRMKIL 219
PRK15100 PRK15100
cystine ABC transporter permease;
269-403 7.24e-17

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 79.02  E-value: 7.24e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 269 PEMVALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIPPLTSQFLNLTKNSSLAVA 348
Cdd:PRK15100  86 DPIPAAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKDTSLAAT 165

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 704419207 349 IAYPDLvqvFMGTVLnQTGRAVEIVSITMA---VYLAISLVTSALMGVYNRRVRLVER 403
Cdd:PRK15100 166 IQVPEL---FRQAQL-ITSRTLEVFTMYLAaslIYWIMATVLSALQNRFENQLNRQER 219
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
271-397 7.02e-15

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 73.33  E-value: 7.02e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 271 MVALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIPPLTSQFLNLTKNSSLAVAIA 350
Cdd:PRK15107  97 LISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLTQGIVLFQDTSLVYVLS 176

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 704419207 351 YPDLVQVfMGTVLNQTGRAVEIVSITMAVYLAISLVTSALMGVYNRR 397
Cdd:PRK15107 177 LADFFRT-ASTIGERDGTQVEMILFAGFVYFVISLSASLLVSYLKKR 222
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 269-397 7.60e-13

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 67.19  E-value: 7.60e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207  269 PEMVALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIPPLTSQFLNLTKNSSLAVA 348
Cdd:TIGR03003  84 PALVAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLVAMFKETPVLSA 163

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 704419207  349 IAYPDLVQVfMGTVLNQTGRAVEIVSITMAVYLAISLVTSALMGVYNRR 397
Cdd:TIGR03003 164 ITVLELMNQ-AKSIGNSTFRYLEPMTLVGVFFLILSIISVFFLRRLEAR 211
PRK11123 PRK11123
arginine ABC transporter permease ArtQ;
275-403 3.78e-12

arginine ABC transporter permease ArtQ;


Pssm-ID: 182979 [Multi-domain]  Cd Length: 238  Bit Score: 65.47  E-value: 3.78e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 275 VVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIPPLTSQFLNLTKNSSLAVAIAYPDL 354
Cdd:PRK11123 108 VIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPGLGNQWLVLLKDTALVSLISVNDL 187

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 704419207 355 VQVFMGTVLNqTGRAVEIVSITMAVYLAISLVTSALMGVYNRRVRLVER 403
Cdd:PRK11123 188 MLQTKSIATR-TQEPFTWYIIAAAIYLVITLISQYILKRIELRATRFER 235
HEQRo_perm_3TM TIGR01726
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ...
 93-154 3.86e-12

amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130787 [Multi-domain]  Cd Length: 99  Bit Score: 62.16  E-value: 3.86e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 704419207   93 AFVVGLLNTLLVAAIGIVLATLIGFLVGIARLSSNVVVAAVATLYVETLRNLPLLLQIFFWY 154
Cdd:TIGR01726   4 FLLKGLLLTLLLSVLSILLGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIY 65
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 271-399 1.73e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 48.06  E-value: 1.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207  271 MVALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIPPLTSQFLNLTKNSSLAVAI- 349
Cdd:pfam00528  52 ILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLg 131

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 704419207  350 AYPDLVQVFMGTVLN-QTGRAVEIVSITMAVYLAISLVTSALMGVYNRRVR 399
Cdd:pfam00528 132 SWPGLGLLLIEAILGyDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 273-387 3.52e-06

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 47.27  E-value: 3.52e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 273 ALVVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIPPLTSQFLNLTKNSSLAVAIAYP 352
Cdd:cd06261   75 PALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGG 154

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 704419207 353 DLVQVFMGTVLNQTGRAVEIVSITMAVYLAISLVT 387
Cdd:cd06261  155 EAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
PRK15069 PRK15069
histidine ABC transporter permease HisM;
275-397 3.34e-04

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 41.96  E-value: 3.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 275 VVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVITPQALRVIIPPLTSQFLNLTKNSSLAVAIAYPDL 354
Cdd:PRK15069 106 ILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALPAYSNEVILMLHATTLAFTATVPDI 185

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 704419207 355 VQVfMGTVLNQTGRAVEIVSITMAVYLAISLVTSALMGVYNRR 397
Cdd:PRK15069 186 LKI-ARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAERR 227
artM PRK11122
arginine ABC transporter permease ArtM;
275-403 6.11e-04

arginine ABC transporter permease ArtM;


Pssm-ID: 182978 [Multi-domain]  Cd Length: 222  Bit Score: 41.10  E-value: 6.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 704419207 275 VVALSTYTAAFIAEIVRAGIGAVGQGQREAAVALGLSPRHTQSLVItPQALRVIIPPLTSQFLNLTKNSSLAVAIAYPDL 354
Cdd:PRK11122  95 MLALALNSAAYSTQLFYGAVRAIPEGQWQSCAALGMSKKQTLRILL-PYAFKRALSSYSNEVVLVFKSTSLAYTITLMDV 173

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 704419207 355 vqvfMGTVLNQTGRA--VEIVSITMAVYLAISLVTSALMGVYNRRVRLVER 403
Cdd:PRK11122 174 ----MGYSQLLYGRTydVMVFGAAGIIYLVVNGLLTLLMRLIERKALAFER 220
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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