|
Name |
Accession |
Description |
Interval |
E-value |
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
7-518 |
0e+00 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 519.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 7 RLIVFICALLLGVGFSVPSLLETKGP------------KITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQ 74
Cdd:PRK05812 2 KYLLILLVLLIGLLYALPNLRGALAPatpewlpalgakPMKLGLDLRGGVHFLLEVDMDDALKKRLESLADDLRSLLREK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 75 NILLKdikssleGISFELLDEDEVKKLDALLLELQGhsqfeikkeagfysvkLTPLEQEELRKNTILQVIGIIRNRLDQF 154
Cdd:PRK05812 82 KIRYG-------GVEITFRDAEDRDKAIALLRKLSS----------------LTEAELKEITEEALEQAIEIIRNRVNEL 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 155 GLAEPVVIQQGREEISVQLPGIKtleEERRAKDLISRSAHLQMMAVDeehnkdamkmtdleaqklgsvllsdvemggkil 234
Cdd:PRK05812 139 GVAEPVIQRQGADRIVVELPGVQ---DTARAKEILGKTATLEFRLVP--------------------------------- 182
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 235 lkaiPILDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGNF 314
Cdd:PRK05812 183 ----VILTGDDITDASASFDQQGQPVVNITLDSEGAKKFADITKANIGKRMAIVLDGEVISAPVIQSAITGGSAQITGNF 258
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 315 SVAQASDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACLALVVNLFLIVA 394
Cdd:PRK05812 259 TAEEARDLALLLRAGALPAPLEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILYYRLFGLIANIALVANLVLILA 338
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 395 VMAIFGATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTG 474
Cdd:PRK05812 339 VLSLLGATLTLPGIAGIVLTIGMAVDANVLIFERIREELREGRSLRSAIEAGFKRAFSTILDSNITTLIAAIILYALGTG 418
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 727100692 475 AIKGFALTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFW 518
Cdd:PRK05812 419 PVKGFAVTLGIGILTSMFTAITVTRALVNLLYGRRKRLKKLSIG 462
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
104-502 |
4.08e-170 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 486.02 E-value: 4.08e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 104 LLLELQGHSQFEIKKEAG-FYSVKLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPVVIQQGREEISVQLPGIktlEEE 182
Cdd:TIGR01129 1 LGLDLRGGARVLLEVDMStAVVLKLSEAEVNAIRKDALEQVITILRNRVNALGVSEPVVQRQGKDRIVVELPGV---TDT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 183 RRAKDLISRSAHLQMMAVDEEHNKDAMKMTDLEAQklGSVLLSDVEMGGK-ILLKAIPILDGEMLTDAKVVYDQNN-QPV 260
Cdd:TIGR01129 78 SRAKDILGGTATLEFRLVDDESTSPDDALAGNVPA--GSELLDSRSGDPKyYLLKKSPVLTGDHITDATSSVDQRSgQPV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 261 VSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGNFSVAQASDLAIALRSGAMSAPIQVLEK 340
Cdd:TIGR01129 156 VSFSLDSEGARIFGDFTQANIGKRLAIVLDNKVVSAPTIQEAITGGSGQITGNFTAEEANDLALVLRSGALPAPLQILEE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 341 RIIGPSLGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVD 420
Cdd:TIGR01129 236 RTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVD 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 421 ANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFALTTGIGILASIITAIVGTQG 500
Cdd:TIGR01129 316 ANVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLFTALVFTRL 395
|
..
gi 727100692 501 IY 502
Cdd:TIGR01129 396 LL 397
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
1-506 |
3.35e-154 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 447.25 E-value: 3.35e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 1 MKLFNARLIVFICALLLGVGFSVPSLLETKgpkITLGLDLRGGLNMLLGVQTDEALKNkylslasaleynakkqnillkd 80
Cdd:COG0342 1 MKAKFLLWRLLLLLLVVALSLVAPNGPAKP---IKLGLDLQGGVHLLLEVDTDAALDE---------------------- 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 81 iksslegisfelldedevkkldalllelqghsqfeikkeagfysvklTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPV 160
Cdd:COG0342 56 -----------------------------------------------DGDGIREVTEEALDQAIEILRNRVNELGVSEPV 88
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 161 VIQQGREEISVQLPGIKTLEeerRAKDLISRSAHLQMMAVDEEHNKDAmkmtdleAQKLGSVLLSDVEmGGKILLKAIPI 240
Cdd:COG0342 89 IQRQGDDRIVVELPGVQDPA---EAKELLGKTAKLEFRLVDDSADAQA-------AVPAGSELLPCRD-GQPYLLLGPVV 157
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 241 LDGEMLTDAKVVYD-QNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGNFSVAQA 319
Cdd:COG0342 158 LTGDDLTDASAGFDqQTGQPVVSFTLDSEGAKKFADATRENVGKPLAIVLDGEVISAPVIQEPITGGSAQITGSFTVEEA 237
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 320 SDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACLALVVNLFLIVAVMAIF 399
Cdd:COG0342 238 QDLALLLRAGALPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYRLPGLVANIALALNVVLLLGVLSLL 317
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 400 GATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGF 479
Cdd:COG0342 318 GATLTLPGIAGIILTIGMAVDANVLIFERIREELRAGRSLRAAIEAGFKRAFSTILDANVTTLIAAVVLFVLGTGPVKGF 397
|
490 500
....*....|....*....|....*..
gi 727100692 480 ALTTGIGILASIITAIVGTQGIYQALL 506
Cdd:COG0342 398 AVTLILGILISMFTAVPVTRPLLNLLL 424
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
8-523 |
5.77e-118 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 364.94 E-value: 5.77e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 8 LIVFICALLLGVGFSVPSLLETKgpKITLGLDLRGGLNMLLGVQtdealknkylslasaleynakkqnillkdikssleg 87
Cdd:PRK13024 7 VIFFLTLLLLIGIYYASPKFVTK--NINLGLDLQGGFEVLLEVS------------------------------------ 48
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 88 isfellDEDEVKKLDalllelqghsqfeikkeagfysvkltpleqeelrKNTILQVIGIIRNRLDQFGLAEPVVIQQGRE 167
Cdd:PRK13024 49 ------PADKGKKAD----------------------------------REALDSTVEVLRNRIDGLGVSEPNIQREGNN 88
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 168 EISVQLPGIKtleEERRAKDLISRSAHLQMMAVDEEHNKDAmkmtdlEAQKLGSVLLSDVEMGGKILLkaipilDGEMLT 247
Cdd:PRK13024 89 RIRVELPGVQ---DPERARELLGSTAKLTFRDVTDPPPPGV------GGPVVGPDEGKDTAVLNPVLL------SGDDLT 153
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 248 DAKVVYDQ--NNQPVVSFTLDAQGAKIFGDFSGANV-----GKRMAIVLDNKVYSAPVIRERIGGGSGQISGNFSVAQAS 320
Cdd:PRK13024 154 DAGAKFDQdqTNRPSVSLKLKSEGAKKWAKVTEKNSkkgppNNRIAIVLDPKVISAPTVNQPINGGSVQISGNFTVEEAK 233
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 321 DLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACLALVVNLFLIVAVMAIFG 400
Cdd:PRK13024 234 DLANLLNAGALPAPLKIIESRSVGPTLGQDAIDAGIIAGIIGFALIFLFMLVYYGLPGLIANIALLLYIFLTLGALSSLG 313
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 401 ATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA 480
Cdd:PRK13024 314 AVLTLPGIAGLVLGIGMAVDANVLIFERIKEELRKGKSLKKAFKKGFKNAFSTILDSNITTLIAAAILFFFGTGPVKGFA 393
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 727100692 481 LTTGIGILASIITAIVGTQGIYQALLPKltqTKSLYFWFGVNK 523
Cdd:PRK13024 394 TTLIIGILASLFTAVFLTRLLLELLVKR---GDKKPFLFGVKK 433
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
14-494 |
2.57e-98 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 315.89 E-value: 2.57e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 14 ALLLGVGFSVPSLLETK----------GPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKDIKS 83
Cdd:PRK14726 15 VVLAGVAIAAPNLLSEAqlaslpswlpHRQVTLGLDLQGGSHIVLKVERSDIVKDRLEETVANIRNALRDAGIRYTGLTG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 84 SLEGISFELLDEDEVKKLDALLLELQGHSQFEIKKEAGFYSVKLTPLEQEELRKN------------TILQVIGIIRNRL 151
Cdd:PRK14726 95 NGQTVQVRITDPAQTQAAVDALKPLTAPVSAGGLGGSSIQELTLQEGGEGQLRLQltdagidyrvssALTQSIEVVRRRV 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 152 DQFGLAEPVVIQQGREEISVQLPGiktLEEERRAKDLISRSAHLQMMAVDEEHN-KDAMkmtDLEAQKLGSVLLSDVEMG 230
Cdd:PRK14726 175 AELGTTEPLIRRQGDDRIVVQVPG---LVDPQRLKNLLNQPAKLSFRLVDSSMPaQEAL---NGRPPATSEVLYSLDDPP 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 231 GKILLKAIPILDGEMLTDAKVVYD-QNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQ 309
Cdd:PRK14726 249 VPYLVERRAFVSGENLVDAQPVFDpQTNEPVVTFRLDAEGTQRFAQATQQNVGKHFAIVLDGQVISAPVIDEAITGGEGR 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 310 ISGNFSVAQASDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACLALVVNL 389
Cdd:PRK14726 329 ISGNFSEQGANDLAVLLRAGALPATLTVVEERTVGPGLGADSIAAGLVAGLIAAILVAALMIGFYGFLGVIAVIALIVNV 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 390 FLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLY 469
Cdd:PRK14726 409 VLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSNVLIYERIREEEKTGHSLIQALDRGFSRALATIVDANVTILIAAVILF 488
|
490 500
....*....|....*....|....*
gi 727100692 470 AYGTGAIKGFALTTGIGILASIITA 494
Cdd:PRK14726 489 FLGSGAVRGFAVTLAVGILTTVFTA 513
|
|
| secD |
PRK12933 |
protein translocase subunit SecD; |
16-495 |
4.83e-91 |
|
protein translocase subunit SecD;
Pssm-ID: 183831 [Multi-domain] Cd Length: 604 Bit Score: 290.43 E-value: 4.83e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 16 LLGVGFSvpslletkgpKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKDIK-SSLEGISFELLD 94
Cdd:PRK12933 118 LQNMGFS----------PIKLGLDLRGGVQFLLDVDVDPVYQEQRDALVDSVRQFLREQRIRGVSVRlDDSDQLAVTTPD 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 95 EDEVKKLDALLLelQGHSQFEIKKEAGF-YSVKLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPVVIQQGREEISVQL 173
Cdd:PRK12933 188 NDARSAVRQFIQ--QNYPGWQVTNSDDRgLQLKLSQQEKTKFRNLTVQQNLQIMRSRIEELGITEALVQRQGEHRIRIEL 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 174 PGIKTLEEerrAKDLISRSAHLQMMAVDEEHNKDAMKMTDleaqklgsvllsdvEMGGKILLKAIPILDGEMLTDAKVVY 253
Cdd:PRK12933 266 PGVQDPAA---AKNVIGATASLAFYEVKESGSVNAKVLKD--------------KNGRPVYVARRPVLGGEHIVDARASL 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 254 DQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMA-------------IVLDNKVYSAPVIRERIGGGSGQISGNfSVAQAS 320
Cdd:PRK12933 329 GEMGMAEVNISLDRAGGKKMSDFSRDNIGKPMAtsyseysrdeqgkTKQSEEVISVATIQSQLGDRFRITGAG-SYQEAQ 407
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 321 DLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACLALVVNLFLIVAVMA-IF 399
Cdd:PRK12933 408 QLALLLRAGSLTAPVTIVEERTIGPSLGAENIENGFAALALGMGITLLFMALWYRRLGWVANVALIANMVCLFGLLAlIP 487
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 400 GATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGF 479
Cdd:PRK12933 488 GAVLTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKEGRSFAQAIDTGFDSAFSTIFDANFTTMITAVVLYSIGNGPIQGF 567
|
490
....*....|....*.
gi 727100692 480 ALTTGIGILASIITAI 495
Cdd:PRK12933 568 ALTLGLGLLTSMFTGI 583
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
146-499 |
6.13e-59 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 208.32 E-value: 6.13e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 146 IIRNRLDQFGLAEPVVIQQGREEISVQLPGiktLEEERRAKDLISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLS 225
Cdd:PRK13023 75 IMRQRLEELGYGNPVVEGEGRNQIRVEVPG---LYDAQLLKDILTIRGNLSFRAMDDTMSPDDAIRGTPPADSEIVYSFD 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 226 DVEMGgkILLKAIPILDGEMLTDAKV-VYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIG 304
Cdd:PRK13023 152 DPPVG--YLLKKTPILTGHDITDAKAsISADDGQPVITLTLDDNGRRRLADLTAQGNENSFAIVVDNQVVSAPTVSGPLD 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 305 GGSGQISGNFSVAQASDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACLA 384
Cdd:PRK13023 230 TSELQIEGAFDLQAANNMAVVLRSGALPQAVTVLEERTIASALGEDYASAAVLAALLAALVVGLFMVLSYGILGVIALVA 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 385 LVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIA 464
Cdd:PRK13023 310 LVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRRKGYSVVQAMESGFYRALSTIVDANLTTLIA 389
|
330 340 350
....*....|....*....|....*....|....*
gi 727100692 465 SVLLYAYGTGAIKGFALTTGIGILASIITAIVGTQ 499
Cdd:PRK13023 390 ALVLFLLGSGTVHGFALTVAIGIGTTLFTTLTFTR 424
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
265-495 |
2.11e-54 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 181.69 E-value: 2.11e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 265 LDAQGAKIFGDFSGANVGKrmAIVLDN-KVYSAPVIRerigggsgqisgnfsvaqasdlaialrsgamsapiqvlekrII 343
Cdd:TIGR00916 1 LDEEGAKIFADFAANIGKP--AIVLDNaKVISAPVVG-----------------------------------------TV 37
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 344 GPSLGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACLALVVN-LFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDAN 422
Cdd:TIGR00916 38 GPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHdVILILGVLSLFGATLTLPGIAGLLTIIGYSVDDT 117
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 727100692 423 IIINERIREVLRENEG--IAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFALTTGIGILASIITAI 495
Cdd:TIGR00916 118 VVIFDRIREELRKYKGrtFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
274-513 |
1.31e-49 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 183.91 E-value: 1.31e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 274 GDFSGaNVGKRMAIVLDNKVYSAPVIRErIGGGSGQISGNFSVAQASDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIK 353
Cdd:PRK12911 832 GQFSG-GRGWRMAVVLDGYVVSDPVLNV-PLKDHASVSGKFSHREVHRLATDLKSGAMSFVPEVLSEEVISPELGKSQRT 909
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 354 TSIIALVGGFILVMGFMALYYSMAGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIINERIREVL 433
Cdd:PRK12911 910 QGIISVCLGLAVLIVLMSVYYRFGGVIASGAVLLNLLLIWAALQYLDAPLTLSGLAGIVLAMGMAVDANVLVFERIREEY 989
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 434 RENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFALTTGIGILASIITAIVGTQGIYQALLPKLTQTK 513
Cdd:PRK12911 990 LLSRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTALFMTKFFFMIWMNKTQETQ 1069
|
|
| secD |
PRK08343 |
preprotein translocase subunit SecD; Reviewed |
132-488 |
4.34e-22 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 236245 [Multi-domain] Cd Length: 417 Bit Score: 98.41 E-value: 4.34e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 132 QEELRKNTILQVIGIIRNRLDQFGLAEPVVIQQGREEISVQLPGiktlEEERRAKDLISRSAHLQMMAVDEEHNkdamkm 211
Cdd:PRK08343 57 EGPVTQETMDLVVEILESRLNALGLKDIKVYPVGDQYIVVEVPG----VDADTAKEIIEKQGVFEARIQTPGNN------ 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 212 tdleaqklGSVLLSdvemGGKILLKAIPILDgemltdakvvyDQNNQPVVSFTLDAQGAKIFGD------FSGANVGKRM 285
Cdd:PRK08343 127 --------NETVLT----GDDIESVGSPSQD-----------PSGGAWGVPFTLSEDGAEKFAEvakgkgATDDPSGHPL 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 286 AIVLDNKVYSAPVIRERIGGGSGQISGNFSVA----------QASDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTS 355
Cdd:PRK08343 184 DMYLDGELIYAAPLSPDLASGLASGPVVITVGstgtteeakeEAKELYIHLRSGALPVKLDIEGSGSVSPSLGEQFKKGS 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 356 IIALVGGFILVMGFMALYY---SMAG--VIACLALVVnlfLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIINErir 430
Cdd:PRK08343 264 LIAGLLALLAVALVVFLRYrepRIALpmVITSLSEVI---IILGFAALIGWQLDLASIAGIIAVIGTGVDDLIIITD--- 337
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 727100692 431 EVLRENEGIAKAIHLGYInaSRA---IFDSNITSLIASVLLYAYGTGAIKGFALTTGIGIL 488
Cdd:PRK08343 338 EVLHEGKVPSRKVFLSRI--KRAffiIFAAAATTIAAMSPLAVMGLGDLKGFAITTILGVL 396
|
|
| SecF |
COG0341 |
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ... |
343-498 |
2.14e-15 |
|
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440110 [Multi-domain] Cd Length: 291 Bit Score: 76.63 E-value: 2.14e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 343 IGPSLGKDSIKTSIIALVGGFILVMGFMALY----YSMAGVIaclALVVNLFLIVAVMAIFGATLTLPGMAGIvLTV-GI 417
Cdd:COG0341 123 VGPTVGKELTRKALLALLVALIGILIYIAFRfewrFAVGAVV---ALLHDVLITLGIFSLFGLEFDLTFIAAL-LTIiGY 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 418 AVDANIIINERIREVLREN--EGIAKAIHLGyINA--SRAIFDSnITSLIASVLLYAYGTGAIKGFALTTGIGIlasiit 493
Cdd:COG0341 199 SLNDTVVVFDRIRENLRKYrkMTLAEIINLS-INQtlSRTINTS-LTTLLVVLALLFFGGETLRDFALALLIGI------ 270
|
....*
gi 727100692 494 aIVGT 498
Cdd:COG0341 271 -IVGT 274
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
314-498 |
3.15e-13 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 69.61 E-value: 3.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 314 FSVAQASDLAIALRSGAMSAPIQVLEkrIIGPSLGKDSIKTSIIALVGGFILVMGFMALYY--SMAgVIACLALVVNLFL 391
Cdd:TIGR00966 61 QSEELREALEEALKNVDPDAEIRSID--AVGPSVGGELARKAVLALLAALVLILIYITVRFewRFA-LGAIVALVHDVII 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 392 IVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEG--IAKAIHLGyINA--SRAIFDSnITSLIASVL 467
Cdd:TIGR00966 138 TVGVYSLFGIEVNLTTVAALLTIIGYSINDTVVVFDRIRENLRKYTRktFTEVINLS-INQtlSRTINTS-LTTLLAVLA 215
|
170 180 190
....*....|....*....|....*....|.
gi 727100692 468 LYAYGTGAIKGFALTTGIGIlasiitaIVGT 498
Cdd:TIGR00966 216 LYVFGGGVIKDFSLALLVGV-------IVGT 239
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
335-495 |
4.45e-13 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 67.63 E-value: 4.45e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 335 IQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMALYYSMA-GVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVL 413
Cdd:pfam02355 13 AEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRfALGAIIALAHDVIITVGVFSLFGIEVDLATVAALLT 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 414 TVGIAVDANIIINERIREVLRE--NEGIAKAIHLGyINA--SRAIFDSnITSLIASVLLYAYGTGAIKGFALTTGIGILA 489
Cdd:pfam02355 93 IIGYSVNDTVVVFDRVRENLRKktRATLNEIMNLS-INQtlTRTINTS-LTTLLVVVALFVFGGGSLKDFSLALLVGVIV 170
|
....*.
gi 727100692 490 SIITAI 495
Cdd:pfam02355 171 GTYSSI 176
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
352-496 |
1.84e-10 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 63.73 E-value: 1.84e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 352 IKTSIIALVGGFILVMGFMALYYS--MAGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIINERI 429
Cdd:COG1033 604 IESQIRSLLLALLLIFLLLLLAFRslRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRY 683
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 727100692 430 REVLRENEGIAKAIHLGYINASRAIFDSNITsLIASVLLYAY-GTGAIKGFALTTGIGILASIITAIV 496
Cdd:COG1033 684 REERRKGGDLEEAIRRALRTTGKAILFTSLT-LAAGFGVLLFsSFPPLADFGLLLALGLLVALLAALL 750
|
|
| secF |
PRK13021 |
preprotein translocase subunit SecF; Reviewed |
335-498 |
2.56e-10 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 237274 [Multi-domain] Cd Length: 297 Bit Score: 61.41 E-value: 2.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 335 IQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACL-ALVVNLFLIVAVMAIFGATLTLPGMAGIVL 413
Cdd:PRK13021 108 VQVLNSSIVGPQVGQELAEQGGLALLVAMLCILGYLSYRFEWRLASGALfALVHDVIFVLAFFALTQMEFNLTVLAAVLA 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 414 TVGIAVDANIIINERIREVLRENEGIA-KAIHLGYINA--SRAIFDSNiTSLIASVLLYAYGTGAIKGFALTTGIGILAS 490
Cdd:PRK13021 188 ILGYSLNDSIIIADRIRELLIAKPKLAiQEINNQAIVAtfSRTMVTSG-TTLMTVGALWIMGGGPLEGFSIAMFIGILTG 266
|
....*....
gi 727100692 491 IITAI-VGT 498
Cdd:PRK13021 267 TFSSIsVGT 275
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
334-498 |
5.17e-10 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 62.17 E-value: 5.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 334 PIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMAL----YYSMAGVIAclaLVVNLFLIVAVMAIFGATLTLPGMA 409
Cdd:PRK13024 558 GGTIPSSETVGPTVGKELARNAIIAVLIALIGILLYILIrfewTFSLGAILA---LLHDVLIVIGFFSLFRLEVDLTFIA 634
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 410 GIVLTVGIAVDANIIINERIREVLRENEG--IAKAIHLGyIN--ASRAIFDSnITSLIASVLLYAYGTGAIKGFALTTGI 485
Cdd:PRK13024 635 AILTIIGYSINDTVVVFDRIRENLRLYKKkdLREIVNKS-INqtLSRTINTS-LTTLLVLLALLIFGGSSLRNFSLALLV 712
|
170
....*....|...
gi 727100692 486 GIlasiitaIVGT 498
Cdd:PRK13024 713 GL-------IVGT 718
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
355-503 |
1.49e-09 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 60.62 E-value: 1.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 355 SIIALVGGFILVMGFMALYYSmagviaclaLVVNLFLIVAVMAIFGATLTLPGMAGI----------VLTVGIAVDANII 424
Cdd:TIGR00921 570 RRMTIAGAILVLMILLAVFRN---------PIKAVFPLIAIGSGILWAIGLMGLRGIpsflamattiSIILGLGMDYSIH 640
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 727100692 425 INERIREVLRENeGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFALTTGIGILASIITAIVGTQGIYQ 503
Cdd:TIGR00921 641 LAERYFEERKEH-GPKEAITHTMERTGPGILFSGLTTAGGFLSLLLSHFPIMRNFGLVQGIGVLSSLTAALVVFPALLV 718
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
346-496 |
8.44e-09 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 58.33 E-value: 8.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 346 SLGKDSIKTSIIAlvggFILVMGFMALYY-SMAGVIACLA-LVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANI 423
Cdd:COG1033 215 AIQSDLAIFFPLA----LLLILLLLFLFFrSLRGVLLPLLvVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGI 290
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 727100692 424 IINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFALTTGIGILASIITAIV 496
Cdd:COG1033 291 HLLNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVLLAFLTSLT 363
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
337-496 |
1.10e-08 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 58.25 E-value: 1.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 337 VLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVG 416
Cdd:NF037998 429 VNGISEFNPVVTLLMLIASIIFLLILAIAIMIYLLFAYRLLGLFAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIG 508
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 417 IAVDANIIINERI-REVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFALTTGIGILASIITAI 495
Cdd:NF037998 509 LVLESCSLLFEAFkKHLYKNKRSIEESFKIANKETIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVI 588
|
.
gi 727100692 496 V 496
Cdd:NF037998 589 I 589
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
359-496 |
1.98e-07 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 53.70 E-value: 1.98e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 359 LVGGFILVMGFMAL-YYSMAGVIACLA-LVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIINERirevlREN 436
Cdd:COG4258 645 LLLALLLILLLLLLrLRSLRRALRVLLpPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYALFFTEG-----LLD 719
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 437 EGIAKAIHLgyinasrAIFDSNITSLIASVLLYAYGTGAIKGFALTTGIGILASIITAIV 496
Cdd:COG4258 720 KGELARTLL-------SILLAALTTLLGFGLLAFSSTPALRSFGLTVLLGILLALLLAPL 772
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
349-519 |
2.50e-06 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 50.29 E-value: 2.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 349 KDSIKTSIIALVGGFILVMGFMALYYS--MAGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIIN 426
Cdd:PRK15127 334 KISIHEVVKTLVEAIILVFLVMYLFLQnfRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVV 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 427 ERIREVLREnEGI----AKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAI-KGFALTTGIGILASIITAIVGTQGI 501
Cdd:PRK15127 414 ENVERVMAE-EGLppkeATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIyRQFSITIVSAMALSVLVALILTPAL 492
|
170 180
....*....|....*....|....
gi 727100692 502 YQALLPKLTQ------TKSLYFWF 519
Cdd:PRK15127 493 CATMLKPIAKgdhgegKKGFFGWF 516
|
|
| PRK08578 |
PRK08578 |
preprotein translocase subunit SecF; Reviewed |
343-496 |
8.99e-06 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 236302 [Multi-domain] Cd Length: 292 Bit Score: 47.62 E-value: 8.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 343 IGPSLGKDSIKTSIIALVGGFIlvmgFMAL--YYSMAGVIACLALVVNLF----LIVAVMAIFGATLTLPGMAGIVLTVG 416
Cdd:PRK08578 124 IGPTFGSQFQEQALKAVGFAFI----GMAVvvFLIFRTPVPSLAVILSAFsdiiIALALMNLFGIELSLATVAALLMLIG 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 417 IAVDANIIINERireVLRE----NEGIAKAIHLGyinasraiFDSNITSLIASVLLYAygtgaikgFALTTGIGILASIi 492
Cdd:PRK08578 200 YSVDSDILLTTR---VLKRrgtfDESIKRAMRTG--------ITMTLTTIAAMAVLYI--------VSTIPQAEVLANI- 259
|
....
gi 727100692 493 tAIV 496
Cdd:PRK08578 260 -AAV 262
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
342-495 |
9.83e-06 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 48.46 E-value: 9.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 342 IIGPS----LGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACLALVVnlfLIVAVMAIFGATLTLPGMAGIVLTVGI 417
Cdd:PRK13023 567 VVGPTvseqLSRAGVLAVILSLIGIFIYVWFRFRWQLALGAVLSTLHDVV---ILSGMFIVFRMEFNLWSVAAILTIIGY 643
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 418 AVDANIIINERIREVLRENEGIA-KAIHLGYINA--SRAIFDSNITsLIASVLLYAYGTGAIKGFALTTGIGILASIITA 494
Cdd:PRK13023 644 SLNDTVVIYDRVRENLRRYKSAPlPAIIDASINQtlSRTLLTSFVT-FLAHVPLYAFGGSEIRMFALALSVGIIVASYSS 722
|
.
gi 727100692 495 I 495
Cdd:PRK13023 723 I 723
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
347-506 |
3.95e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 46.37 E-value: 3.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 347 LGKDSIKTSIIAlvgGFILVMgfmALYYSMAGVIA-CLALVVNLFLIVAV---MAIFGATLTLPGMAGIVLTVGIAVDAN 422
Cdd:TIGR00921 191 FGKDMGTTMAIS---GILVVL---VLLLDFKRWWRpLLPLVIILFGVAWVlgiMGWLGIPLYATTLLAVPMLIGVGIDYG 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 423 IIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFalttGIGILASIITAIVGTQGIY 502
Cdd:TIGR00921 265 IQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEF----GLGLVAGLITAYLLTLLVL 340
|
....
gi 727100692 503 QALL 506
Cdd:TIGR00921 341 PALL 344
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
351-495 |
6.86e-05 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 45.75 E-value: 6.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 351 SIKTSIIALVGGFILVmgFMALYYSM----AGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIIN 426
Cdd:pfam00873 329 SIEEVVKTLLEAIVLV--ILVMFLFLqnwrATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVVDDAIVVV 406
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 727100692 427 ERIREVLREN-EGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYG--TGAI-KGFALTTGIGILASIITAI 495
Cdd:pfam00873 407 ENIERVLEENgLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGglTGRIfRQFAITIVLAILLSVLVAL 479
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
349-519 |
1.37e-04 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 44.82 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 349 KDSIKTSIIALVGGFILVMGFMALYYS--MAGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIIN 426
Cdd:PRK10555 334 KASIEDVVKTLLEAIALVFLVMYLFLQnfRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIGLLVDDAIVVV 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 427 ERIREVLREnEGI----AKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAI-KGFALTTGIGILASIITAIVGTQGI 501
Cdd:PRK10555 414 ENVERIMSE-EGLtpreATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIyRQFSITIVSAMVLSVLVAMILTPAL 492
|
170 180
....*....|....*....|...
gi 727100692 502 YQALLPKLTQT-----KSLYFWF 519
Cdd:PRK10555 493 CATLLKPLKKGehhgqKGFFGWF 515
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
349-495 |
2.35e-04 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 43.94 E-value: 2.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 349 KDSIKTSIIALVGGFILVMGFMALY-YSM-AGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIIN 426
Cdd:COG0841 327 RASIEEVVKTLLEAILLVVLVVFLFlRSWrATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVVDDAIVVV 406
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 727100692 427 ERIREVLRENEGIAKAIhlgyINASR----AIFDSNITSLIASV-LLYAYG-TGAI-KGFALTTGIGILASIITAI 495
Cdd:COG0841 407 ENIERHMEEGLSPLEAA----IKGARevagAVIASTLTLVAVFLpLAFMGGiTGQLfRQFALTVAIALLISLFVAL 478
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
351-519 |
3.10e-04 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 43.69 E-value: 3.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 351 SIKTSIIALVGGFILVMGFMALYYS--MAGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIINER 428
Cdd:PRK09577 335 SMNKVVTTLIEAGVLVFLVMFLFMQnfRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVLAIGILVDDAIVVVEN 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 429 IREVLREnEGIAKaiHLGYINASRAIFDS--NITSLIASVLL-YAYGTGAI----KGFALTTGIGILASIITAIVGTQGI 501
Cdd:PRK09577 415 VERLMVE-EGLSP--YDATVKAMKQISGAivGITVVLTSVFVpMAFFGGAVgniyRQFALSLAVSIGFSAFLALSLTPAL 491
|
170 180
....*....|....*....|..
gi 727100692 502 YQALLPKLTQ----TKSLYFWF 519
Cdd:PRK09577 492 CATLLKPVDGdhheKRGFFGWF 513
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
357-498 |
3.64e-04 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 42.66 E-value: 3.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 357 IALVGGFILVMGFMALYY---SMAGVI-----ACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLtVGIAVDANIIINER 428
Cdd:pfam03176 146 LIEAVTLVVIFIILLIVYrsvVAALLPlltvgLSLGAAQGLVAILAHILGIGLSTFALNLLVVLL-IAVGTDYALFLVSR 224
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 429 IREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFALTTGIGILasIITAIVGT 498
Cdd:pfam03176 225 YREELRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVL--VDVLAALT 292
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
379-495 |
5.59e-04 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 42.83 E-value: 5.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 379 VIACLALVVNLFLIVA---VMAIFGATLTLPGMAGIVLTV---GIAVDANIIINERIREVLRENEGIAKAIHLGYINASR 452
Cdd:COG2409 194 VAALLPLLTAGLAVGValgLLALLAAFTDVSSFAPNLLTMlglGVGIDYALFLVSRYREELRAGEDREEAVARAVATAGR 273
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 727100692 453 AIFDSNITSLIASVLLYAYGTGAIKGFALTTGIGILASIITAI 495
Cdd:COG2409 274 AVLFSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVAVLAAL 316
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
356-496 |
3.79e-03 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 39.97 E-value: 3.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 356 IIALVGGFiLVMGfmALYYSMAGVIACLaLVVNLFLIVAVMA--IFGATLTLPGMAGIVLTVGIAVDANIIINERIREvL 433
Cdd:pfam00873 869 ALALLVVF-LVLA--ALYESWSDPLSIM-LTVPLALVGALLAlwLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANE-L 943
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 727100692 434 RENEG--IAKAIHLGYINASRAIFdsnITSLIAS--VLLYAYGTGAIKGFALTTGIGILASIITAIV 496
Cdd:pfam00873 944 REQEGksLEEAILEACRLRLRPIL---MTALAAIlgVLPLALSTGAGSELQQPLGIVVFGGLVTSTV 1007
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
319-498 |
3.79e-03 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 40.10 E-value: 3.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 319 ASDLAIALRSGA--------MSAPIQVLEK------RIIGP----SLGKDSIKTSIIALVGGFILVMGFMALYYS--MAG 378
Cdd:TIGR00915 286 ASGLAIKLATGAnaldtakaVKAELAVLEPffpqgmKYVYPydttPFVEASIEEVVHTLIEAIVLVFLVMYLFLQnfRAT 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 379 VIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENegiakaiHLGYINASRAIFDSN 458
Cdd:TIGR00915 366 LIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAIGLLVDDAIVVVENVERVMAEE-------GLPPKEATRKSMGQI 438
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 727100692 459 ITSLIASVL----------LYAYGTGAI-KGFALTTGIGILASIITAIVGT 498
Cdd:TIGR00915 439 QGALVGIAMvlsavfvpmaFFGGSTGAIyRQFSITIVSAMALSVLVALILT 489
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
317-506 |
5.14e-03 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 39.60 E-value: 5.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 317 AQASDLAIALRSGAmsapiQVlekRIIGP-SLGKDSIKTS----IIALVGGFILVMGFMAL-YYSMAGVIACLA-LVVNL 389
Cdd:TIGR03480 236 AAAKDLRLDEDHGV-----TV---RLTGEvALSDEELATVsegaTVAGLLSFVLVLVLLWLaLRSPRLVFAVLVtLIVGL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 390 FLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFdsnITSLIASVLLY 469
Cdd:TIGR03480 308 ILTAAFATLAVGHLNLISVAFAVLFIGLGVDFAIQFSLRYREERFRGGNHREALSVAARRMGAALL---LAALATAAGFF 384
|
170 180 190
....*....|....*....|....*....|....*....
gi 727100692 470 AYGTGAIKGFAlttGIGILA--SIITAIVGTQGIYQALL 506
Cdd:TIGR03480 385 AFLPTDYKGVS---ELGIIAgtGMFIALFVTLTVLPALL 420
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
319-494 |
6.26e-03 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 39.32 E-value: 6.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 319 ASDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMAL----YYSMAGVIACLALVVnlfLIVA 394
Cdd:PRK14726 638 AEQSAVTLVRGELEDDYDFRRVEVVGPAVSGELTMAATLGVLAALAAILIYIWIrfewQFAVGAIIATLHDVI---LTLG 714
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 395 VMAIFGATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHL-GYINA--SRAIFDSnITSLIASVLLYAY 471
Cdd:PRK14726 715 LFVLTGIEFNLTSIAAILTIVGYSLNDTVVVYDRVRENLRRYKKMPLPILIdASINQtlSRTVLTS-ATTLLALLALYLF 793
|
170 180
....*....|....*....|....*..
gi 727100692 472 GTGAIKGFALT----TGIGILASIITA 494
Cdd:PRK14726 794 GGEVIRSFTFAmlfgVAVGTFSSIYIA 820
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
349-497 |
6.36e-03 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 39.32 E-value: 6.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 349 KDSIKTSIIALVGGFILVmgFM---ALY--YSMAGVIaCLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANI 423
Cdd:COG0841 847 QESFSSLGLAFLLALLLV--YLvlaAQFesFIQPLII-LLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAI 923
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727100692 424 IINERIREVLRENEGIAKAIhlgyINAS----RAIFdsnITSL--IASVLLYAYGTGAikgfalttGIGILASIITAIVG 497
Cdd:COG0841 924 LLVDFANQLREEGMSLREAI----LEAArlrlRPIL---MTSLatILGLLPLALGTGA--------GAEFRQPLGIAVIG 988
|
|
| |
