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Conserved domains on  [gi|727182650|ref|WP_033644970|]
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MULTISPECIES: Sec-independent protein translocase protein TatB [Serratia]

Protein Classification

Sec-independent protein translocase subunit TatB( domain architecture ID 10019022)

Sec-independent protein translocase subunit TatB, together with TatC, forms the binding site that directly interacts with Tat signal peptides within the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
tatB TIGR01410
twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a ...
 2-81 2.00e-23

twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a Sec-independent system for transporting folded proteins, often with a bound redox cofactor, across the bacterial inner membrane. TatC is the multiple membrane spanning component. TatB, like the related TatA/E proteins, appears to span the membrane one time. The tat system recognizes proteins with an elongated signal sequence containing a conserved R-R in a motif approximated by RRxFLK N-terminal to the transmembrane helix. TIGRFAMs model TIGR01409 describes this twin-Arg signal sequence. A similar system, termed Delta-pH-dependent transport, operates on chloroplast-encoded proteins. [Protein fate, Protein and peptide secretion and trafficking]


:

Pssm-ID: 130477 [Multi-domain]  Cd Length: 80  Bit Score: 88.14  E-value: 2.00e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727182650    2 FDIGFSELLLVLVIGLVVLGPERLPVAVRTVSGWIRALRSLAASVQHELSQELKLQELQDSLKKAEQAGLQNLTPELKAS 81
Cdd:TIGR01410   1 FDIGFSELLLIAVVALVVLGPERLPVAIRTVGGFVRALRGMASDVKNELDEELKLQELDDQLKKAQQARFLNLTAELKDS 80
 
Name Accession Description Interval E-value
tatB TIGR01410
twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a ...
 2-81 2.00e-23

twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a Sec-independent system for transporting folded proteins, often with a bound redox cofactor, across the bacterial inner membrane. TatC is the multiple membrane spanning component. TatB, like the related TatA/E proteins, appears to span the membrane one time. The tat system recognizes proteins with an elongated signal sequence containing a conserved R-R in a motif approximated by RRxFLK N-terminal to the transmembrane helix. TIGRFAMs model TIGR01409 describes this twin-Arg signal sequence. A similar system, termed Delta-pH-dependent transport, operates on chloroplast-encoded proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 130477 [Multi-domain]  Cd Length: 80  Bit Score: 88.14  E-value: 2.00e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727182650    2 FDIGFSELLLVLVIGLVVLGPERLPVAVRTVSGWIRALRSLAASVQHELSQELKLQELQDSLKKAEQAGLQNLTPELKAS 81
Cdd:TIGR01410   1 FDIGFSELLLIAVVALVVLGPERLPVAIRTVGGFVRALRGMASDVKNELDEELKLQELDDQLKKAQQARFLNLTAELKDS 80
PRK04654 PRK04654
sec-independent translocase; Provisional
 1-92 2.08e-09

sec-independent translocase; Provisional


Pssm-ID: 135173 [Multi-domain]  Cd Length: 214  Bit Score: 54.82  E-value: 2.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727182650   1 MFDIGFSELLLVLVIGLVVLGPERLPVAVRTVSGWIRALRSLAASVQHELSQELKLQELQDSLKKAeQAGLQNLTPELKA 80
Cdd:PRK04654   1 MFDIGVGELTLIAVVALVVLGPERLPKAARFAGLWVRRARMQWDSVKQELERELEAEELKRSLQDV-QASLREAEDQLRN 79

                         90
                 ....*....|..
gi 727182650  81 SMDELKDAAESL 92
Cdd:PRK04654  80 TQQQVEQGARAL 91
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-69 1.27e-07

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 46.85  E-value: 1.27e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 727182650   1 MFDIGFSELLLVLVIGLVVLGPERLPVAVRTVSGWIRALRSLAASVQHELSQELKLQELQDSLKKAEQA 69
Cdd:COG1826    1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEELDEELKEEELRKSEKEAEEL 69
 
Name Accession Description Interval E-value
tatB TIGR01410
twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a ...
 2-81 2.00e-23

twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a Sec-independent system for transporting folded proteins, often with a bound redox cofactor, across the bacterial inner membrane. TatC is the multiple membrane spanning component. TatB, like the related TatA/E proteins, appears to span the membrane one time. The tat system recognizes proteins with an elongated signal sequence containing a conserved R-R in a motif approximated by RRxFLK N-terminal to the transmembrane helix. TIGRFAMs model TIGR01409 describes this twin-Arg signal sequence. A similar system, termed Delta-pH-dependent transport, operates on chloroplast-encoded proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 130477 [Multi-domain]  Cd Length: 80  Bit Score: 88.14  E-value: 2.00e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727182650    2 FDIGFSELLLVLVIGLVVLGPERLPVAVRTVSGWIRALRSLAASVQHELSQELKLQELQDSLKKAEQAGLQNLTPELKAS 81
Cdd:TIGR01410   1 FDIGFSELLLIAVVALVVLGPERLPVAIRTVGGFVRALRGMASDVKNELDEELKLQELDDQLKKAQQARFLNLTAELKDS 80
PRK04654 PRK04654
sec-independent translocase; Provisional
 1-92 2.08e-09

sec-independent translocase; Provisional


Pssm-ID: 135173 [Multi-domain]  Cd Length: 214  Bit Score: 54.82  E-value: 2.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727182650   1 MFDIGFSELLLVLVIGLVVLGPERLPVAVRTVSGWIRALRSLAASVQHELSQELKLQELQDSLKKAeQAGLQNLTPELKA 80
Cdd:PRK04654   1 MFDIGVGELTLIAVVALVVLGPERLPKAARFAGLWVRRARMQWDSVKQELERELEAEELKRSLQDV-QASLREAEDQLRN 79

                         90
                 ....*....|..
gi 727182650  81 SMDELKDAAESL 92
Cdd:PRK04654  80 TQQQVEQGARAL 91
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-69 1.27e-07

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 46.85  E-value: 1.27e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 727182650   1 MFDIGFSELLLVLVIGLVVLGPERLPVAVRTVSGWIRALRSLAASVQHELSQELKLQELQDSLKKAEQA 69
Cdd:COG1826    1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEELDEELKEEELRKSEKEAEEL 69
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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