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Conserved domains on  [gi|727282788|ref|WP_033740815|]
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MULTISPECIES: transaldolase [Pantoea]

Protein Classification

transaldolase( domain architecture ID 10793634)

transaldolase transfers a C3 ketol fragment from a ketose donor to an aldose acceptor as part of the non-oxidative branch of the pentose phosphate pathway

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12346 PRK12346
transaldolase A; Provisional
 1-316 0e+00

transaldolase A; Provisional


:

Pssm-ID: 183458  Cd Length: 316  Bit Score: 715.34  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   1 MNQLEALKQFTTVVADSGDIESIRNYHPQDATTNPSLILKASALQPYKHLIDDAIDYAKKQGGSKETQIINASDKVAINL 80
Cdd:PRK12346   1 MNQLDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLPQYQHLIDDAIAWGKKQGGTQEQQVVAACDKLAVNF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  81 GMEILKSIPGRVSTEVDARLSFDRGMCVTKAEKLVRMYEEHGIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSF 160
Cdd:PRK12346  81 GAEILKSVPGRVSTEVDARLSFDREKSIEKARHLVDLYQQQGIDKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 161 AQARACAEAGVYLISPFVGRIYDWYNSRKPMDPYNVDEDPGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVLALAGCDR 240
Cdd:PRK12346 161 AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHRYETIVMGASFRRTEQILALAGCDR 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 727282788 241 LTLSPNLLEELQNSEAPVERKLEPSTECFHQPSPLSEAEFRWEHNQDPMAVEKLADGIRQFAVDQQKLEDVLAARL 316
Cdd:PRK12346 241 LTISPNLLKELQESESPVERKLIPSSQTFPRPAPMSEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL 316
 
Name Accession Description Interval E-value
PRK12346 PRK12346
transaldolase A; Provisional
 1-316 0e+00

transaldolase A; Provisional


Pssm-ID: 183458  Cd Length: 316  Bit Score: 715.34  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   1 MNQLEALKQFTTVVADSGDIESIRNYHPQDATTNPSLILKASALQPYKHLIDDAIDYAKKQGGSKETQIINASDKVAINL 80
Cdd:PRK12346   1 MNQLDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLPQYQHLIDDAIAWGKKQGGTQEQQVVAACDKLAVNF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  81 GMEILKSIPGRVSTEVDARLSFDRGMCVTKAEKLVRMYEEHGIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSF 160
Cdd:PRK12346  81 GAEILKSVPGRVSTEVDARLSFDREKSIEKARHLVDLYQQQGIDKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 161 AQARACAEAGVYLISPFVGRIYDWYNSRKPMDPYNVDEDPGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVLALAGCDR 240
Cdd:PRK12346 161 AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHRYETIVMGASFRRTEQILALAGCDR 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 727282788 241 LTLSPNLLEELQNSEAPVERKLEPSTECFHQPSPLSEAEFRWEHNQDPMAVEKLADGIRQFAVDQQKLEDVLAARL 316
Cdd:PRK12346 241 LTISPNLLKELQESESPVERKLIPSSQTFPRPAPMSEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL 316
talAB TIGR00874
transaldolase; This family includes the majority of known and predicted transaldolase ...
 2-316 0e+00

transaldolase; This family includes the majority of known and predicted transaldolase sequences, including E. coli TalA and TalB. It excluded two other families. The first includes E. coli transaldolase-like protein TalC. The second family includes the putative transaldolases of Helicobacter pylori and Mycobacterium tuberculosis. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 162081  Cd Length: 317  Bit Score: 537.04  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788    2 NQLEALKQFTTVVADSGDIESIRNYHPQDATTNPSLILKASALQPYKHLIDDAIDYAKKQGGSKETQIINASDKVAINLG 81
Cdd:TIGR00874   1 NQLDQLKQFTVVVADTGDIEAIKKYQPQDATTNPSLILAAAQLPKYAELIDEAVAWGKKQGKDDAQQVENALDKLAVNFG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   82 MEILKSIPGRVSTEVDARLSFDRGMCVTKAEKLVRMYEEHGIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFA 161
Cdd:TIGR00874  81 LEILKIVPGRVSTEVDARLSFDTEATVEKARHLIKLYEDAGVDKKRILIKIASTWEGIRAAEELEKEGIHCNLTLLFSFV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  162 QARACAEAGVYLISPFVGRIYDWYNSRKPMDPYNVDEDPGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVLALAGCDRL 241
Cdd:TIGR00874 161 QAIACAEAKVTLISPFVGRILDWYKAATGKKEYSIEEDPGVASVKKIYNYYKKHGYPTEVMGASFRNKEEILALAGCDRL 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 727282788  242 TLSPNLLEELQNSEAPVERKLEPSTEC--FHQPSPLSEAEFRWEHNQDPMAVEKLADGIRQFAVDQQKLEDVLAARL 316
Cdd:TIGR00874 241 TISPALLDELKESTGPVERKLDPESAKkvDKQPIILDESEFRFLHNEDAMATEKLAEGIRKFAADQEKLEKLLEEKL 317
Transaldolase_TalAB cd00957
Transaldolases including both TalA and TalB; Transaldolases including both TalA and TalB. The ...
 2-309 0e+00

Transaldolases including both TalA and TalB; Transaldolases including both TalA and TalB. The enzyme catalyses the reversible transfer of a dyhydroxyacetone moiety, derived from fructose-6-phosphate to erythrose-4-phosphate yielding sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate. The catalytic mechanism is similar to other class I aldolases. The enzyme is found in the non-oxidative branch of the pentose phosphate pathway and forms a dimer in solution.


Pssm-ID: 188644 [Multi-domain]  Cd Length: 313  Bit Score: 530.65  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   2 NQLEALKQFTTVVADSGDIESIRNYHPQDATTNPSLILKASALQPYKHLIDDAIDYAKKQGGSKETQIINASDKVAINLG 81
Cdd:cd00957    1 NQLDQLKKFTTIVADTGDFEAIKKFKPQDATTNPSLILAAAKLPEYNKLVDEAIAYAKKKGGSDEDQISNALDKLLVNFG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  82 MEILKSIPGRVSTEVDARLSFDRGMCVTKAEKLVRMYEEHGIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFA 161
Cdd:cd00957   81 TEILKLIPGRVSTEVDARLSFDTNATIAKARKLIKLYEEAGIDKERILIKIAATWEGIQAAKQLEKEGIHCNLTLLFSFA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 162 QARACAEAGVYLISPFVGRIYDWYNSRKPMDPYNVDEDPGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVLALAGCDRL 241
Cdd:cd00957  161 QAVACAEAGVTLISPFVGRILDWYKKHSGDKAYTAEEDPGVASVKKIYNYYKKFGYKTKVMGASFRNIGQILALAGCDYL 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 242 TLSPNLLEELQNSEAPVERKLEP--STECFHQPSPLSEAEFRWEHNQDPMAVEKLADGIRQFAVDQQKLE 309
Cdd:cd00957  241 TISPALLEELKNSTAKVERKLDPaaSKALDIHPNFLDESAFRWALNEDAMAVEKLSEGIRGFAKDAVKLE 310
TAL_FSA pfam00923
Transaldolase/Fructose-6-phosphate aldolase; Transaldolase (TAL) is an enzyme of the pentose ...
 13-312 6.45e-97

Transaldolase/Fructose-6-phosphate aldolase; Transaldolase (TAL) is an enzyme of the pentose phosphate pathway (PPP) found almost ubiquitously in the three domains of life (Archaea, Bacteria, and Eukarya). TAL shares a high degree of structural similarity and sequence identity with fructose-6-phosphate aldolase (FSA). They both belong to the class I aldolase family. Their protein structures have been revealed.


Pssm-ID: 395737 [Multi-domain]  Cd Length: 226  Bit Score: 285.59  E-value: 6.45e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   13 VVADSGDIESIRNYHP----QDATTNPSLILKASAlqpYKHLIDDAIDYAKKQGgsketqiinasdkvainlgmeilksi 88
Cdd:pfam00923   1 IWLDTADRDLIKKLIEeggiDGVTTNPSIFLKAIE---YSALYDEAIAEIKEIG-------------------------- 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   89 PGRVSTEVDARLSFDRGMCVTKAEKLVRMYEehgidRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFAQARACAE 168
Cdd:pfam00923  52 DGPVSLEVDPRLADDTEGTIEEARRLIALYG-----RPNVLIKIPATWEGIKAIKELSAEGINVNVTLIFSLAQALAAAE 126

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  169 AGVYLISPFVGRIYDWYNSRKPMDPynvDEDPGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVLALAGCDRLTLSPNLL 248
Cdd:pfam00923 127 AGASVISPFVGRIDDWGDKRLGAAL---RGDDGIANAKEIYQIYKKYGWSTGVLAASFRNVLYVLALAGCDTITIPPDTL 203

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 727282788  249 EELQNSEapverklepstecfhqpsplseaefrwehnqdpmavekladGIRQFAVDQQKLEDVL 312
Cdd:pfam00923 204 EALAKDE-----------------------------------------GVRKFAKDWEKLLGSI 226
TalA COG0176
Transaldolase/fructose-6-phosphate aldolase [Carbohydrate transport and metabolism]; ...
 11-308 2.21e-77

Transaldolase/fructose-6-phosphate aldolase [Carbohydrate transport and metabolism]; Transaldolase/fructose-6-phosphate aldolase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 439946 [Multi-domain]  Cd Length: 214  Bit Score: 235.35  E-value: 2.21e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  11 TTVVADSGDIESIRNYH----PQDATTNPSLILKASalqpykhlIDDAIDYAKkqggsketqiinasdkvainlgmEILK 86
Cdd:COG0176    1 MKLWLDTADREEIKELIdlggVDGVTTNPSLIAKAG--------IKDFVEDIR-----------------------EICD 49

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  87 SIPGRVSTEVdarLSFDRGMCVTKAEKLvrmyeeHGIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFAQARAC 166
Cdd:COG0176   50 IVDGPVSAEV---LATDTEGMIAEARRL------AALYRPNVVIKIPATEEGLKAIEELSAEGIKVNVTLIFSAAQALLA 120

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 167 AEAGVYLISPFVGRIYDWynsrkpmdpyNVDedpGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVL--ALAGCDRLTLS 244
Cdd:COG0176  121 AEAGASYVSPFVGRIDDI----------GID---GIALVREIYQIYKNYGARTRILAASFRNPLQVLeaALAGADTVTIP 187

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 727282788 245 PNLLEELQNSeapverklepstecfhqpsplseaefrwehnqdpmavEKLADGIRQFAVDQQKL 308
Cdd:COG0176  188 PAVLEALADH-------------------------------------PLTDEGIEKFLADWEKL 214
 
Name Accession Description Interval E-value
PRK12346 PRK12346
transaldolase A; Provisional
 1-316 0e+00

transaldolase A; Provisional


Pssm-ID: 183458  Cd Length: 316  Bit Score: 715.34  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   1 MNQLEALKQFTTVVADSGDIESIRNYHPQDATTNPSLILKASALQPYKHLIDDAIDYAKKQGGSKETQIINASDKVAINL 80
Cdd:PRK12346   1 MNQLDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLPQYQHLIDDAIAWGKKQGGTQEQQVVAACDKLAVNF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  81 GMEILKSIPGRVSTEVDARLSFDRGMCVTKAEKLVRMYEEHGIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSF 160
Cdd:PRK12346  81 GAEILKSVPGRVSTEVDARLSFDREKSIEKARHLVDLYQQQGIDKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 161 AQARACAEAGVYLISPFVGRIYDWYNSRKPMDPYNVDEDPGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVLALAGCDR 240
Cdd:PRK12346 161 AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHRYETIVMGASFRRTEQILALAGCDR 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 727282788 241 LTLSPNLLEELQNSEAPVERKLEPSTECFHQPSPLSEAEFRWEHNQDPMAVEKLADGIRQFAVDQQKLEDVLAARL 316
Cdd:PRK12346 241 LTISPNLLKELQESESPVERKLIPSSQTFPRPAPMSEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL 316
PRK05269 PRK05269
transaldolase B; Provisional
 1-316 0e+00

transaldolase B; Provisional


Pssm-ID: 235381 [Multi-domain]  Cd Length: 318  Bit Score: 615.63  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   1 MNQLEALKQFTTVVADSGDIESIRNYHPQDATTNPSLILKASALQPYKHLIDDAIDYAKKQGGSKETQIINASDKVAINL 80
Cdd:PRK05269   2 TNKLEQLKQFTTVVADTGDIEAIKKYQPQDATTNPSLILKAAQIPEYAPLIDDAVAWAKQQSGDRAQQIDDAIDKLAVNF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  81 GMEILKSIPGRVSTEVDARLSFDRGMCVTKAEKLVRMYEEHGIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSF 160
Cdd:PRK05269  82 GLEILKLIPGRVSTEVDARLSFDTEATIAKARKLIALYEEAGISKDRILIKIASTWEGIRAAEQLEKEGINCNLTLLFSF 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 161 AQARACAEAGVYLISPFVGRIYDWYNSRKPMDPYNVDEDPGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVLALAGCDR 240
Cdd:PRK05269 162 AQARACAEAGVFLISPFVGRILDWYKKNTGKKEYAPAEDPGVVSVTKIYNYYKKHGYKTVVMGASFRNTGQILELAGCDR 241

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 727282788 241 LTLSPNLLEELQNSEAPVERKLEPSTECFHQPSPLSEAEFRWEHNQDPMAVEKLADGIRQFAVDQQKLEDVLAARL 316
Cdd:PRK05269 242 LTISPALLEELAASEGELERKLSPPGEAKARPVPLTEAEFRWQHNEDAMATEKLAEGIRKFAKDQEKLEKLIAAKL 317
talAB TIGR00874
transaldolase; This family includes the majority of known and predicted transaldolase ...
 2-316 0e+00

transaldolase; This family includes the majority of known and predicted transaldolase sequences, including E. coli TalA and TalB. It excluded two other families. The first includes E. coli transaldolase-like protein TalC. The second family includes the putative transaldolases of Helicobacter pylori and Mycobacterium tuberculosis. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 162081  Cd Length: 317  Bit Score: 537.04  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788    2 NQLEALKQFTTVVADSGDIESIRNYHPQDATTNPSLILKASALQPYKHLIDDAIDYAKKQGGSKETQIINASDKVAINLG 81
Cdd:TIGR00874   1 NQLDQLKQFTVVVADTGDIEAIKKYQPQDATTNPSLILAAAQLPKYAELIDEAVAWGKKQGKDDAQQVENALDKLAVNFG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   82 MEILKSIPGRVSTEVDARLSFDRGMCVTKAEKLVRMYEEHGIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFA 161
Cdd:TIGR00874  81 LEILKIVPGRVSTEVDARLSFDTEATVEKARHLIKLYEDAGVDKKRILIKIASTWEGIRAAEELEKEGIHCNLTLLFSFV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  162 QARACAEAGVYLISPFVGRIYDWYNSRKPMDPYNVDEDPGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVLALAGCDRL 241
Cdd:TIGR00874 161 QAIACAEAKVTLISPFVGRILDWYKAATGKKEYSIEEDPGVASVKKIYNYYKKHGYPTEVMGASFRNKEEILALAGCDRL 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 727282788  242 TLSPNLLEELQNSEAPVERKLEPSTEC--FHQPSPLSEAEFRWEHNQDPMAVEKLADGIRQFAVDQQKLEDVLAARL 316
Cdd:TIGR00874 241 TISPALLDELKESTGPVERKLDPESAKkvDKQPIILDESEFRFLHNEDAMATEKLAEGIRKFAADQEKLEKLLEEKL 317
Transaldolase_TalAB cd00957
Transaldolases including both TalA and TalB; Transaldolases including both TalA and TalB. The ...
 2-309 0e+00

Transaldolases including both TalA and TalB; Transaldolases including both TalA and TalB. The enzyme catalyses the reversible transfer of a dyhydroxyacetone moiety, derived from fructose-6-phosphate to erythrose-4-phosphate yielding sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate. The catalytic mechanism is similar to other class I aldolases. The enzyme is found in the non-oxidative branch of the pentose phosphate pathway and forms a dimer in solution.


Pssm-ID: 188644 [Multi-domain]  Cd Length: 313  Bit Score: 530.65  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   2 NQLEALKQFTTVVADSGDIESIRNYHPQDATTNPSLILKASALQPYKHLIDDAIDYAKKQGGSKETQIINASDKVAINLG 81
Cdd:cd00957    1 NQLDQLKKFTTIVADTGDFEAIKKFKPQDATTNPSLILAAAKLPEYNKLVDEAIAYAKKKGGSDEDQISNALDKLLVNFG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  82 MEILKSIPGRVSTEVDARLSFDRGMCVTKAEKLVRMYEEHGIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFA 161
Cdd:cd00957   81 TEILKLIPGRVSTEVDARLSFDTNATIAKARKLIKLYEEAGIDKERILIKIAATWEGIQAAKQLEKEGIHCNLTLLFSFA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 162 QARACAEAGVYLISPFVGRIYDWYNSRKPMDPYNVDEDPGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVLALAGCDRL 241
Cdd:cd00957  161 QAVACAEAGVTLISPFVGRILDWYKKHSGDKAYTAEEDPGVASVKKIYNYYKKFGYKTKVMGASFRNIGQILALAGCDYL 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 242 TLSPNLLEELQNSEAPVERKLEP--STECFHQPSPLSEAEFRWEHNQDPMAVEKLADGIRQFAVDQQKLE 309
Cdd:cd00957  241 TISPALLEELKNSTAKVERKLDPaaSKALDIHPNFLDESAFRWALNEDAMAVEKLSEGIRGFAKDAVKLE 310
PTZ00411 PTZ00411
transaldolase-like protein; Provisional
 1-316 6.92e-176

transaldolase-like protein; Provisional


Pssm-ID: 240406  Cd Length: 333  Bit Score: 489.63  E-value: 6.92e-176
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   1 MNQLEALKQFTTVVADSGDIESIRNYHPQDATTNPSLILKASALQPYKHLIDDAIDYAKKQGGS---------KETQIIN 71
Cdd:PTZ00411   2 PNQLEALKEHTTVVADTGDFSLLKKFQPEDATTNPSLVLAAAQMPEYAHLIDDAIKYAKANVSRlrdpllsdeEKEELVE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  72 -ASDKVAINLGMEILKSIPGRVSTEVDARLSFDRGMCVTKAEKLVRMYEEHGIDRSRILIKLASTWEGIKAAEELEKNGI 150
Cdd:PTZ00411  82 lVVDKLTVNFGVEILKIVPGRVSTEVDARLSFDKQAMVDKARKIIKMYEEAGISKDRILIKLASTWEGIQAAKALEKEGI 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 151 QCNLTLLFSFAQARACAEAGVYLISPFVGRIYDWYNSRKPMDPYNVDEDPGVKSVRRIYDYYKKHRYDTIIMGASFRKVE 230
Cdd:PTZ00411 162 HCNLTLLFSFAQAVACAQAGVTLISPFVGRILDWYKKPEKAESYVGAQDPGVISVTKIYNYYKKHGYKTIVMGASFRNTG 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 231 QVLALAGCDRLTLSPNLLEELQNSEA-PVERKLEP--STECFHQPSPLSEAEFRWEHNQDPMAVEKLADGIRQFAVDQQK 307
Cdd:PTZ00411 242 EILELAGCDKLTISPKLLEELANTEDgPVERKLDPekLTEDTEKLPELTEKEFRWELNEDAMATEKLAEGIRNFAKDLEK 321


                 ....*....
gi 727282788 308 LEDVLAARL 316
Cdd:PTZ00411 322 LENVIRAKL 330
PRK12309 PRK12309
transaldolase;
1-316 5.59e-148

transaldolase;


Pssm-ID: 183426 [Multi-domain]  Cd Length: 391  Bit Score: 421.45  E-value: 5.59e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   1 MNQLEALKQFTTVVADSGDIESIRNYHPQDATTNPSLILKASALQPYKHLIDDAIDYAKKQGGSKET--QIIN-ASDKVA 77
Cdd:PRK12309   3 ASLLEQLRQMTVVVADTGDIQAIEKFTPRDATTNPSLITAAAQMPQYQSIVDETLRQARKELGSDAPveDVVAlAFDRLA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  78 INLGMEILKSIPGRVSTEVDARLSFDRGMCVTKAEKLVRMYEEHGIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLL 157
Cdd:PRK12309  83 VAFGLKILKIVPGRVSTEVDARLSYDTEATIAKARKLISLYEDAGISRDRVLIKIASTWEGIKAAEVLEKEGIHCNLTLL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 158 FSFAQARACAEAGVYLISPFVGRIYDWYNSRKPMDPYNVDEDPGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVLALAG 237
Cdd:PRK12309 163 FGFHQAIACAEAGVTLISPFVGRILDWYKKETGRDSYPGAEDPGVQSVTQIYNYYKKFGYKTEVMGASFRNIGEIIELAG 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 238 CDRLTLSPNLLEELQNSEAPVERKLEPStecfhQPSPLS-------EAEFRWEHNQDPMAVEKLADGIRQFAVDQQKLED 310
Cdd:PRK12309 243 CDLLTISPKLLEQLRSTEAELPRKLDPA-----NAAGMEiekihmdRATFDKMHAEDRMASEKLDEGIKGFSKALETLEK 317


                 ....*.
gi 727282788 311 VLAARL 316
Cdd:PRK12309 318 LLAHRL 323
TAL_FSA pfam00923
Transaldolase/Fructose-6-phosphate aldolase; Transaldolase (TAL) is an enzyme of the pentose ...
 13-312 6.45e-97

Transaldolase/Fructose-6-phosphate aldolase; Transaldolase (TAL) is an enzyme of the pentose phosphate pathway (PPP) found almost ubiquitously in the three domains of life (Archaea, Bacteria, and Eukarya). TAL shares a high degree of structural similarity and sequence identity with fructose-6-phosphate aldolase (FSA). They both belong to the class I aldolase family. Their protein structures have been revealed.


Pssm-ID: 395737 [Multi-domain]  Cd Length: 226  Bit Score: 285.59  E-value: 6.45e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   13 VVADSGDIESIRNYHP----QDATTNPSLILKASAlqpYKHLIDDAIDYAKKQGgsketqiinasdkvainlgmeilksi 88
Cdd:pfam00923   1 IWLDTADRDLIKKLIEeggiDGVTTNPSIFLKAIE---YSALYDEAIAEIKEIG-------------------------- 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788   89 PGRVSTEVDARLSFDRGMCVTKAEKLVRMYEehgidRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFAQARACAE 168
Cdd:pfam00923  52 DGPVSLEVDPRLADDTEGTIEEARRLIALYG-----RPNVLIKIPATWEGIKAIKELSAEGINVNVTLIFSLAQALAAAE 126

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  169 AGVYLISPFVGRIYDWYNSRKPMDPynvDEDPGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVLALAGCDRLTLSPNLL 248
Cdd:pfam00923 127 AGASVISPFVGRIDDWGDKRLGAAL---RGDDGIANAKEIYQIYKKYGWSTGVLAASFRNVLYVLALAGCDTITIPPDTL 203

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 727282788  249 EELQNSEapverklepstecfhqpsplseaefrwehnqdpmavekladGIRQFAVDQQKLEDVL 312
Cdd:pfam00923 204 EALAKDE-----------------------------------------GVRKFAKDWEKLLGSI 226
TalA COG0176
Transaldolase/fructose-6-phosphate aldolase [Carbohydrate transport and metabolism]; ...
 11-308 2.21e-77

Transaldolase/fructose-6-phosphate aldolase [Carbohydrate transport and metabolism]; Transaldolase/fructose-6-phosphate aldolase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 439946 [Multi-domain]  Cd Length: 214  Bit Score: 235.35  E-value: 2.21e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  11 TTVVADSGDIESIRNYH----PQDATTNPSLILKASalqpykhlIDDAIDYAKkqggsketqiinasdkvainlgmEILK 86
Cdd:COG0176    1 MKLWLDTADREEIKELIdlggVDGVTTNPSLIAKAG--------IKDFVEDIR-----------------------EICD 49

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  87 SIPGRVSTEVdarLSFDRGMCVTKAEKLvrmyeeHGIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFAQARAC 166
Cdd:COG0176   50 IVDGPVSAEV---LATDTEGMIAEARRL------AALYRPNVVIKIPATEEGLKAIEELSAEGIKVNVTLIFSAAQALLA 120

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 167 AEAGVYLISPFVGRIYDWynsrkpmdpyNVDedpGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVL--ALAGCDRLTLS 244
Cdd:COG0176  121 AEAGASYVSPFVGRIDDI----------GID---GIALVREIYQIYKNYGARTRILAASFRNPLQVLeaALAGADTVTIP 187

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 727282788 245 PNLLEELQNSeapverklepstecfhqpsplseaefrwehnqdpmavEKLADGIRQFAVDQQKL 308
Cdd:COG0176  188 PAVLEALADH-------------------------------------PLTDEGIEKFLADWEKL 214
Transaldolase cd00439
Transaldolase; Transaldolase. Enzymes found in the non-oxidative branch of the pentose ...
 12-251 1.57e-73

Transaldolase; Transaldolase. Enzymes found in the non-oxidative branch of the pentose phosphate pathway, that catalyze the reversible transfer of a dihydroxyacetone group from fructose-6-phosphate to erythrose-4-phosphate yielding sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate. They are members of the class I aldolases, who are characterized by using a Schiff-base mechanism for stabilization of the reaction intermediates.


Pssm-ID: 188631 [Multi-domain]  Cd Length: 252  Bit Score: 226.85  E-value: 1.57e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  12 TVVADSGDIESI----RNYHPQDATTNPSLILKASALQPYKHLIDDAIDYAKKQGGSKETQIINASDKVAINLGMEILKS 87
Cdd:cd00439    1 SPWYDTLDRPATdllpLIRGVRGVTTNPSIIQAAISTSNAYNDQFRTLVESGKDIESAYWELVVKDIQDACKLFEPIYDQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  88 I--PGRVSTEVDARLSFDRGMCVTKAEKLVRMYEehgidRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFAQARA 165
Cdd:cd00439   81 TeaDGRVSVEVSARLADDTQGMVEAAKYLSKVVN-----RRNIYIKIPATAEGIPAIKDLIAAGISVNVTLIFSIAQYEA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 166 CAEAGVYLISPFVGRIYDWYNSRKPMDPYNVDEDPGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVLALAGCDRLTLSP 245
Cdd:cd00439  156 VADAGTSVASPFVSRIDTLMDKMLEQIGLDLRGKAGVAQVTLAYKLYKQKFKKQRVLWASFSDTLYVAPLIGCDTVTTMP 235


                 ....*.
gi 727282788 246 NLLEEL 251
Cdd:cd00439  236 DQALEA 241
Transaldolase_FSA cd00956
Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; ...
 16-256 6.26e-34

Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea, which are member of the MipB/TalC subfamily of class I aldolases. FSA catalyze an aldol cleavage of fructose 6-phosphate and do not utilize fructose, fructose 1-phosphate, fructose 1,6-phosphate, or dihydroxyacetone phosphate. The enzymes belong to the transaldolase family that serves in transfer reactions in the pentose phosphate cycle, and are more distantly related to fructose 1,6-bisphosphate aldolase.


Pssm-ID: 188643 [Multi-domain]  Cd Length: 211  Bit Score: 123.45  E-value: 6.26e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  16 DSGDIESIRNYHPQ----DATTNPSLILKASALQPYKHLIddaidyakkqggsketqiinasdkvainlgmEILKSIPGR 91
Cdd:cd00956    5 DTADLEEIKKASETglldGVTTNPSLIAKSGRIDFEAVLK-------------------------------EICEIIDGP 53

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  92 VSTEVDARlSFDrGMcVTKAEKLVrmyEEHGidrsRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFAQARACAEAGV 171
Cdd:cd00956   54 VSAQVVST-DAE-GM-VAEARKLA---SLGG----NVVVKIPVTEDGLKAIKKLSEEGIKTNVTAIFSAAQALLAAKAGA 123

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 172 YLISPFVGRIydwynsrkpmDPYNVDEDPGVKSVRRIYDyykKHRYDTIIMGASFRKVEQVL--ALAGCDRLTLSPNLLE 249
Cdd:cd00956  124 TYVSPFVGRI----------DDLGGDGMELIREIRTIFD---NYGFDTKILAASIRNPQHVIeaALAGADAITLPPDVLE 190


                 ....*..
gi 727282788 250 ELQNSEA 256
Cdd:cd00956  191 QLLKHPL 197
Transaldolase_like cd00955
Transaldolase-like proteins from plants and bacteria; Transaldolase-like proteins from plants ...
 31-169 4.52e-16

Transaldolase-like proteins from plants and bacteria; Transaldolase-like proteins from plants and bacteria. Transaldolase is found in the non-oxidative branch of the pentose phosphate pathway, that catalyze the reversible transfer of a dihydroxyacetone group from fructose-6-phosphate to erythrose-4-phosphate yielding sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate. They are members of the class I aldolases, who are characterized by using a Schiff-base mechanism for stabilization of the reaction intermediates.


Pssm-ID: 188642 [Multi-domain]  Cd Length: 338  Bit Score: 77.36  E-value: 4.52e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  31 ATTNPSLILKASALQPYkhlIDDAIDYAKKQGGSKET--------QIINASDKVAINlgMEILKSIPGRVSTEVDARLSF 102
Cdd:cd00955   29 VTSNPAIFEKAIAGSAA---YDDQIRALKGQGLDAEAiyealaieDIQDACDLLAPV--YEQTGGNDGYVSLEVSPRLAD 103

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 727282788 103 DRGMCVTKAEklvRMYEEhgIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFAQARACAEA 169
Cdd:cd00955  104 DTQGTIAEAK---RLWKA--VGRPNLMIKIPATEAGLPAIEELIAAGISVNVTLIFSLEQYEAVAEA 165
PRK03903 PRK03903
transaldolase; Provisional
 90-181 1.23e-11

transaldolase; Provisional


Pssm-ID: 235171  Cd Length: 274  Bit Score: 63.85  E-value: 1.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  90 GRVSTEVDARLSFDRGMCVTKAeklVRMYeeHGIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFAQARACAEA 169
Cdd:PRK03903  43 GFISIEIDPFLEDDAAGSIEEG---KRLY--KTIGRPNVMIKVPATKAGYEAMSALMKKGISVNATLIFSPEQAKECAEA 117

                         90       100
                 ....*....|....*....|....*
gi 727282788 170 -------------GVylISPFVGRI 181
Cdd:PRK03903 118 lneglkkntkdpkAV--ISVFVSRF 140
PRK03343 PRK03343
transaldolase; Validated
 32-173 2.89e-11

transaldolase; Validated


Pssm-ID: 235117  Cd Length: 368  Bit Score: 63.69  E-value: 2.89e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  32 TTNPSLILKA-SALQPYkhliDDAIDYAKKQGGSKE--------TQIINASDkvainlgmeILKSI-------PGRVSTE 95
Cdd:PRK03343  43 TSNPAIFQKAiAGGDAY----DAQIAELAAAGADVEeayeelttADVRNACD---------VLRPVyeatggvDGRVSIE 109

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 727282788  96 VDARLSFDRGMCVTKAeklVRMYEEhgIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFAQARACAEAgvYL 173
Cdd:PRK03343 110 VSPRLAHDTEATIAEA---RRLWAA--VDRPNLMIKIPATPEGLPAIEALIAEGISVNVTLIFSVERYRAVADA--YL 180
PRK12653 PRK12653
fructose-6-phosphate aldolase; Reviewed
 109-256 1.80e-09

fructose-6-phosphate aldolase; Reviewed


Pssm-ID: 183653 [Multi-domain]  Cd Length: 220  Bit Score: 56.71  E-value: 1.80e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788 109 TKAEKLVRMYEE-HGIDRSrILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFAQARACAEAGVYLISPFVGRIydwyns 187
Cdd:PRK12653  63 TTAEGMVNDARKlRSIIAD-IVVKVPVTAEGLAAIKMLKAEGIPTLGTAVYGAAQGLLSALAGAEYVAPYVNRI------ 135

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 727282788 188 rkpmDPYNVDedpGVKSVRRIYDYYKKHRYDTIIMGASFRKVEQVLA--LAGCDRLTLSPNLLEELQNSEA 256
Cdd:PRK12653 136 ----DAQGGS---GIQTVTDLQQLLKMHAPQAKVLAASFKTPRQALDclLAGCESITLPLDVAQQMISYPA 199
PRK09533 PRK09533
bifunctional transaldolase/phosoglucose isomerase; Validated
 32-169 1.18e-06

bifunctional transaldolase/phosoglucose isomerase; Validated


Pssm-ID: 236551 [Multi-domain]  Cd Length: 948  Bit Score: 49.97  E-value: 1.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727282788  32 TTNPSLILKASALQP-YkhliDDAIDYAKKQGGSKETQ---------IINASDkvAINLGMEILKSIPGRVSTEVDARLS 101
Cdd:PRK09533  42 TSNPAIFEKAIGSSDeY----DDAIKAALAEGDRSVIElyetlaiedIQAAAD--VLRPVYDATDGADGFVSLEVSPYLA 115

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 727282788 102 FDRGMCVTKAEKLVRmyeehGIDRSRILIKLASTWEGIKAAEELEKNGIQCNLTLLFSFAQARACAEA 169
Cdd:PRK09533 116 LDTEGTIAEARRLWA-----AVDRPNLMIKVPATPEGLPAIRQLIAEGINVNVTLLFSQDVYEEVAEA 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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