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Conserved domains on  [gi|736533368|ref|WP_034548131|]
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Mrp/NBP35 family ATP-binding protein [Ezakiella coagulans]

Protein Classification

Mrp/NBP35 family ATP-binding protein( domain architecture ID 10566257)

Mrp (multiple resistance and pH adaptation)/NBP35 (nucleotide-binding protein 35) family ATP-binding protein is an iron-sulfur (FeS) cluster protein that functions as a scaffold to assemble nascent FeS clusters for transfer to FeS-requiring enzymes

CATH:  3.40.50.300
Gene Ontology:  GO:0046872|GO:0005524|GO:0051536|GO:0140663|GO:0016226|GO:0016887
PubMed:  8921898

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ParA pfam10609
NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid ...
 19-252 5.96e-109

NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.


:

Pssm-ID: 431392 [Multi-domain]  Cd Length: 246  Bit Score: 314.39  E-value: 5.96e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368   19 NIKRVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIE-EKVYGSEEEIFPNKTGeGIKVMSIN 97
Cdd:pfam10609   1 GVKHVIAVASGKGGVGKSTVAVNLALALARLGYKVGLLDADIYGPSIPRMLGLEgERPEQSDGGIIPVEAH-GIKVMSIG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368   98 LMLPNKTDPVIWRGPILSNILNDFWTKMNWGDLDFLLLDMPPGTGDVPLTIYQHYPVDGVVVVSTPSKMASIAVLKAYEM 177
Cdd:pfam10609  80 FLLPDEDDAVIWRGPMKSGAIKQFLTDVDWGELDYLIIDLPPGTGDEQLTLAQLLPLTGAVIVTTPQDVALLDVRKAIDM 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  178 ALRLNQNVIGEIENMSYYECKECGHKEYLFGE---KEHIE--GLDMLGQVPFDPELGRFIDDGK------IEDTYVMAYD 246
Cdd:pfam10609 160 FKKVNVPVLGVVENMSYFVCPHCGEETYIFGKgggEKLAEelGVPFLGEIPLDPDIREAGDEGKpfvladPDSPAAKAFL 239


                  ....*.
gi 736533368  247 EIVQKI 252
Cdd:pfam10609 240 KIADKV 245
 
Name Accession Description Interval E-value
ParA pfam10609
NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid ...
 19-252 5.96e-109

NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.


Pssm-ID: 431392 [Multi-domain]  Cd Length: 246  Bit Score: 314.39  E-value: 5.96e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368   19 NIKRVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIE-EKVYGSEEEIFPNKTGeGIKVMSIN 97
Cdd:pfam10609   1 GVKHVIAVASGKGGVGKSTVAVNLALALARLGYKVGLLDADIYGPSIPRMLGLEgERPEQSDGGIIPVEAH-GIKVMSIG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368   98 LMLPNKTDPVIWRGPILSNILNDFWTKMNWGDLDFLLLDMPPGTGDVPLTIYQHYPVDGVVVVSTPSKMASIAVLKAYEM 177
Cdd:pfam10609  80 FLLPDEDDAVIWRGPMKSGAIKQFLTDVDWGELDYLIIDLPPGTGDEQLTLAQLLPLTGAVIVTTPQDVALLDVRKAIDM 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  178 ALRLNQNVIGEIENMSYYECKECGHKEYLFGE---KEHIE--GLDMLGQVPFDPELGRFIDDGK------IEDTYVMAYD 246
Cdd:pfam10609 160 FKKVNVPVLGVVENMSYFVCPHCGEETYIFGKgggEKLAEelGVPFLGEIPLDPDIREAGDEGKpfvladPDSPAAKAFL 239


                  ....*.
gi 736533368  247 EIVQKI 252
Cdd:pfam10609 240 KIADKV 245
MrpORP NF041136
iron-sulfur cluster carrier protein MrpORP;
17-255 3.60e-102

iron-sulfur cluster carrier protein MrpORP;


Pssm-ID: 469059 [Multi-domain]  Cd Length: 365  Bit Score: 301.35  E-value: 3.60e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  17 LSNIKRVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKVYGSEEE-IFPNKTGEGIKVMS 95
Cdd:NF041136   1 LSRIKHKILVMSGKGGVGKSTVAANLAVALARRGYKVGLLDVDIHGPSIPKLLGLEGKRLGSEDEgILPVEYSDNLKVMS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  96 INLMLPNKTDPVIWRGPILSNILNDFWTKMNWGDLDFLLLDMPPGTGDVPLTIYQHYPVDGVVVVSTPSKMASIAVLKAY 175
Cdd:NF041136  81 IGFLLENRDDAVIWRGPVKMGVIKQFLSDVEWGDLDYLIIDSPPGTGDEPLSVAQLIPDAGAVIVTTPQELALADVRKSI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368 176 EMALRLNQNVIGEIENMSYYECKECGHKEYLFGEKeHIE------GLDMLGQVPFDPELGRFIDDGKIEDTY------VM 243
Cdd:NF041136 161 NFCRKLNIPILGIVENMSGFVCPHCGKEIDIFKSG-GGEklaeemGVPFLGRIPIDPEIVEAGDAGRPFVLDyawspaAK 239

                        250
                 ....*....|..
gi 736533368 244 AYDEIVQKIKEK 255
Cdd:NF041136 240 ALEKIVDPILEL 251
Mrp_NBP35 cd02037
Mrp/NBP35 ATP-binding protein family; Mrp/NBP35 ATP-binding family protein are typically ...
 22-229 2.16e-94

Mrp/NBP35 ATP-binding protein family; Mrp/NBP35 ATP-binding family protein are typically iron-sulfur (FeS) cluster scaffolds that function to assemble nascent FeS clusters for transfer to FeS-requiring enzymes. Members include the eukaryotic nucleotide-binding protein 1 (NUBP1) which is a component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery and the archael [NiFe] hydrogenase maturation protein HypB which is required for nickel insertion into [NiFe] hydrogenase.


Pssm-ID: 349757 [Multi-domain]  Cd Length: 213  Bit Score: 276.30  E-value: 2.16e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEK-VYGSEEEIFPNKTGeGIKVMSINLML 100
Cdd:cd02037    1 HIIAVLSGKGGVGKSTVAVNLALALAKKGYKVGLLDADIYGPSIPRLLGVEGKpLHQSEEGIVPVEVG-GIKVMSIGFLL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368 101 PNKtDPVIWRGPILSNILNDFWTKMNWGDLDFLLLDMPPGTGDVPLTIYQHYPVDGVVVVSTPSKMASIAVLKAYEMALR 180
Cdd:cd02037   80 PED-DAVIWRGPMKSGAIKQFLKDVDWGELDYLIIDLPPGTGDEHLSLVQLIPIDGAVVVTTPQEVSLIDVRKAIDMCKK 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 736533368 181 LNQNVIGEIENMSYYECKECGHKEYLFGEKEHIE-----GLDMLGQVPFDPELG 229
Cdd:cd02037  159 LNIPVLGIVENMSGFVCPHCGKKIYIFGKGGGEKlaeelGVPFLGKIPLDPELA 212
PRK11670 PRK11670
iron-sulfur cluster carrier protein ApbC;
20-235 1.97e-55

iron-sulfur cluster carrier protein ApbC;


Pssm-ID: 183270 [Multi-domain]  Cd Length: 369  Bit Score: 182.16  E-value: 1.97e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  20 IKRVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKVYGSEE--EIFPNKTgEGIKVMSIN 97
Cdd:PRK11670 106 VKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAEDQRPTSPDgtHMAPIMA-HGLATNSIG 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  98 -LMLPNktDPVIWRGPI----LSNILNDFWtkmnWGDLDFLLLDMPPGTGDVPLTIYQHYPVDGVVVVSTPSKMASIAVL 172
Cdd:PRK11670 185 yLVTDD--NAMVWRGPMaskaLMQMLQETL----WPDLDYLVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAK 258

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 736533368 173 KAYEMALRLNQNVIGEIENMSYYECKECGHKEYLFG--------EKEHIEgldMLGQVPFDPELGRFIDDG 235
Cdd:PRK11670 259 KGIVMFEKVEVPVLGIVENMSMHICSNCGHHEPIFGtggaeklaEKYHTQ---LLGQMPLHISLREDLDRG 326
Mrp COG0489
Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, ...
 22-211 6.30e-51

Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440255 [Multi-domain]  Cd Length: 289  Bit Score: 168.06  E-value: 6.30e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKVYGSE--------EEIFPNKTGEGIKV 93
Cdd:COG0489   93 EVIAVTSGKGGEGKSTVAANLALALAQSGKRVLLIDADLRGPSLHRMLGLENRPGLSDvlageaslEDVIQPTEVEGLDV 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  94 MSINLMLPNKTdpviwrGPILSNILNDFWTKMNwGDLDFLLLDMPPGTGDVPLTIYQHYpVDGVVVVSTPSKMASIAVLK 173
Cdd:COG0489  173 LPAGPLPPNPS------ELLASKRLKQLLEELR-GRYDYVIIDTPPGLGVADATLLASL-VDGVLLVVRPGKTALDDVRK 244

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 736533368 174 AYEMALRLNQNVIGEIENMSyyeckeCGHKEYLFGEKE 211
Cdd:COG0489  245 ALEMLEKAGVPVLGVVLNMV------CPKGERYYGGGE 276
eps_fam TIGR01007
capsular exopolysaccharide family; This model describes the capsular exopolysaccharide ...
 22-191 1.04e-09

capsular exopolysaccharide family; This model describes the capsular exopolysaccharide proteins in bacteria. The exopolysaccharide gene cluster consists of several genes which encode a number of proteins which regulate the exoploysaccharide biosynthesis(EPS). Atleast 13 genes espA to espM in streptococcus species seem to direct the EPS proteins and all of which share high homology. Functional roles were characterized by gene disruption experiments which resulted in exopolysaccharide-deficient phenotypes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273392 [Multi-domain]  Cd Length: 204  Bit Score: 56.68  E-value: 1.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368   22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKVYGSEEEIFPNKT-GEGIKVMSI-NLM 99
Cdd:TIGR01007  18 KVLLITSVKPGEGKSTTSANIAIAFAQAGYKTLLIDGDMRNSVMSGTFKSQNKITGLTNFLSGTTDlSDAICDTNIeNLD 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  100 lpnktdpVIWRGPILSN----ILNDFWTKM-----NWgdLDFLLLDMPPGTGDVPLTIYQHYpVDGVVVVSTPSKMASIA 170
Cdd:TIGR01007  98 -------VITAGPVPPNptelLQSSNFKTLietlrKR--FDYIIIDTPPIGTVTDAAIIARA-CDASILVTDAGKIKKRE 167

                         170       180
                  ....*....|....*....|.
gi 736533368  171 VLKAYEMALRLNQNVIGEIEN 191
Cdd:TIGR01007 168 VKKAKEQLEQAGSNFLGVVLN 188
ParA_partition NF041546
ParA family partition ATPase;
23-59 2.28e-05

ParA family partition ATPase;


Pssm-ID: 469431 [Multi-domain]  Cd Length: 202  Bit Score: 44.08  E-value: 2.28e-05
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 736533368  23 VIAVTSGKGGVGKSvTTSL-LATTLNKKGYKVGVLDCD 59
Cdd:NF041546   1 IIAVLNQKGGVGKT-TLAThLAAALARRGYRVLLVDAD 37
 
Name Accession Description Interval E-value
ParA pfam10609
NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid ...
 19-252 5.96e-109

NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.


Pssm-ID: 431392 [Multi-domain]  Cd Length: 246  Bit Score: 314.39  E-value: 5.96e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368   19 NIKRVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIE-EKVYGSEEEIFPNKTGeGIKVMSIN 97
Cdd:pfam10609   1 GVKHVIAVASGKGGVGKSTVAVNLALALARLGYKVGLLDADIYGPSIPRMLGLEgERPEQSDGGIIPVEAH-GIKVMSIG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368   98 LMLPNKTDPVIWRGPILSNILNDFWTKMNWGDLDFLLLDMPPGTGDVPLTIYQHYPVDGVVVVSTPSKMASIAVLKAYEM 177
Cdd:pfam10609  80 FLLPDEDDAVIWRGPMKSGAIKQFLTDVDWGELDYLIIDLPPGTGDEQLTLAQLLPLTGAVIVTTPQDVALLDVRKAIDM 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  178 ALRLNQNVIGEIENMSYYECKECGHKEYLFGE---KEHIE--GLDMLGQVPFDPELGRFIDDGK------IEDTYVMAYD 246
Cdd:pfam10609 160 FKKVNVPVLGVVENMSYFVCPHCGEETYIFGKgggEKLAEelGVPFLGEIPLDPDIREAGDEGKpfvladPDSPAAKAFL 239


                  ....*.
gi 736533368  247 EIVQKI 252
Cdd:pfam10609 240 KIADKV 245
MrpORP NF041136
iron-sulfur cluster carrier protein MrpORP;
17-255 3.60e-102

iron-sulfur cluster carrier protein MrpORP;


Pssm-ID: 469059 [Multi-domain]  Cd Length: 365  Bit Score: 301.35  E-value: 3.60e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  17 LSNIKRVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKVYGSEEE-IFPNKTGEGIKVMS 95
Cdd:NF041136   1 LSRIKHKILVMSGKGGVGKSTVAANLAVALARRGYKVGLLDVDIHGPSIPKLLGLEGKRLGSEDEgILPVEYSDNLKVMS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  96 INLMLPNKTDPVIWRGPILSNILNDFWTKMNWGDLDFLLLDMPPGTGDVPLTIYQHYPVDGVVVVSTPSKMASIAVLKAY 175
Cdd:NF041136  81 IGFLLENRDDAVIWRGPVKMGVIKQFLSDVEWGDLDYLIIDSPPGTGDEPLSVAQLIPDAGAVIVTTPQELALADVRKSI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368 176 EMALRLNQNVIGEIENMSYYECKECGHKEYLFGEKeHIE------GLDMLGQVPFDPELGRFIDDGKIEDTY------VM 243
Cdd:NF041136 161 NFCRKLNIPILGIVENMSGFVCPHCGKEIDIFKSG-GGEklaeemGVPFLGRIPIDPEIVEAGDAGRPFVLDyawspaAK 239

                        250
                 ....*....|..
gi 736533368 244 AYDEIVQKIKEK 255
Cdd:NF041136 240 ALEKIVDPILEL 251
Mrp_NBP35 cd02037
Mrp/NBP35 ATP-binding protein family; Mrp/NBP35 ATP-binding family protein are typically ...
 22-229 2.16e-94

Mrp/NBP35 ATP-binding protein family; Mrp/NBP35 ATP-binding family protein are typically iron-sulfur (FeS) cluster scaffolds that function to assemble nascent FeS clusters for transfer to FeS-requiring enzymes. Members include the eukaryotic nucleotide-binding protein 1 (NUBP1) which is a component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery and the archael [NiFe] hydrogenase maturation protein HypB which is required for nickel insertion into [NiFe] hydrogenase.


Pssm-ID: 349757 [Multi-domain]  Cd Length: 213  Bit Score: 276.30  E-value: 2.16e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEK-VYGSEEEIFPNKTGeGIKVMSINLML 100
Cdd:cd02037    1 HIIAVLSGKGGVGKSTVAVNLALALAKKGYKVGLLDADIYGPSIPRLLGVEGKpLHQSEEGIVPVEVG-GIKVMSIGFLL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368 101 PNKtDPVIWRGPILSNILNDFWTKMNWGDLDFLLLDMPPGTGDVPLTIYQHYPVDGVVVVSTPSKMASIAVLKAYEMALR 180
Cdd:cd02037   80 PED-DAVIWRGPMKSGAIKQFLKDVDWGELDYLIIDLPPGTGDEHLSLVQLIPIDGAVVVTTPQEVSLIDVRKAIDMCKK 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 736533368 181 LNQNVIGEIENMSYYECKECGHKEYLFGEKEHIE-----GLDMLGQVPFDPELG 229
Cdd:cd02037  159 LNIPVLGIVENMSGFVCPHCGKKIYIFGKGGGEKlaeelGVPFLGKIPLDPELA 212
PRK11670 PRK11670
iron-sulfur cluster carrier protein ApbC;
20-235 1.97e-55

iron-sulfur cluster carrier protein ApbC;


Pssm-ID: 183270 [Multi-domain]  Cd Length: 369  Bit Score: 182.16  E-value: 1.97e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  20 IKRVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKVYGSEE--EIFPNKTgEGIKVMSIN 97
Cdd:PRK11670 106 VKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAEDQRPTSPDgtHMAPIMA-HGLATNSIG 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  98 -LMLPNktDPVIWRGPI----LSNILNDFWtkmnWGDLDFLLLDMPPGTGDVPLTIYQHYPVDGVVVVSTPSKMASIAVL 172
Cdd:PRK11670 185 yLVTDD--NAMVWRGPMaskaLMQMLQETL----WPDLDYLVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAK 258

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 736533368 173 KAYEMALRLNQNVIGEIENMSYYECKECGHKEYLFG--------EKEHIEgldMLGQVPFDPELGRFIDDG 235
Cdd:PRK11670 259 KGIVMFEKVEVPVLGIVENMSMHICSNCGHHEPIFGtggaeklaEKYHTQ---LLGQMPLHISLREDLDRG 326
Mrp COG0489
Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, ...
 22-211 6.30e-51

Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440255 [Multi-domain]  Cd Length: 289  Bit Score: 168.06  E-value: 6.30e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKVYGSE--------EEIFPNKTGEGIKV 93
Cdd:COG0489   93 EVIAVTSGKGGEGKSTVAANLALALAQSGKRVLLIDADLRGPSLHRMLGLENRPGLSDvlageaslEDVIQPTEVEGLDV 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  94 MSINLMLPNKTdpviwrGPILSNILNDFWTKMNwGDLDFLLLDMPPGTGDVPLTIYQHYpVDGVVVVSTPSKMASIAVLK 173
Cdd:COG0489  173 LPAGPLPPNPS------ELLASKRLKQLLEELR-GRYDYVIIDTPPGLGVADATLLASL-VDGVLLVVRPGKTALDDVRK 244

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 736533368 174 AYEMALRLNQNVIGEIENMSyyeckeCGHKEYLFGEKE 211
Cdd:COG0489  245 ALEMLEKAGVPVLGVVLNMV------CPKGERYYGGGE 276
CbiA pfam01656
CobQ/CobB/MinD/ParA nucleotide binding domain; This family consists of various cobyrinic acid ...
 24-236 5.76e-18

CobQ/CobB/MinD/ParA nucleotide binding domain; This family consists of various cobyrinic acid a,c-diamide synthases. These include CbiA and CbiP from S.typhimurium, and CobQ from R. capsulatus. These amidases catalyze amidations to various side chains of hydrogenobyrinic acid or cobyrinic acid a,c-diamide in the biosynthesis of cobalamin (vitamin B12) from uroporphyrinogen III. Vitamin B12 is an important cofactor and an essential nutrient for many plants and animals and is primarily produced by bacteria. The family also contains dethiobiotin synthetases as well as the plasmid partitioning proteins of the MinD/ParA family.


Pssm-ID: 426369 [Multi-domain]  Cd Length: 228  Bit Score: 80.08  E-value: 5.76e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368   24 IAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDlTGPSIPEIFGIEEKVYGSEEEIF---------------PNKTG 88
Cdd:pfam01656   1 IAIAGTKGGVGKTTLAANLARALARRGLRVLLIDLD-PQSNNSSVEGLEGDIAPALQALAeglkgrvnldpillkEKSDE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368   89 EGIKV--MSINLMLPNKTDPVIWRGPILSNILNdfwtKMNwGDLDFLLLDMPPGTGDvpLTIYQHYPVDGVVVVSTPSKM 166
Cdd:pfam01656  80 GGLDLipGNIDLEKFEKELLGPRKEERLREALE----ALK-EDYDYVIIDGAPGLGE--LLRNALIAADYVIIPLEPEVI 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 736533368  167 A---------SIAVLKAYEMALRLnqNVIGEIENMSYYECKECGHKEYLfgeKEHIEGLDMLGQVPFDPELGRFIDDGK 236
Cdd:pfam01656 153 LvedakrlggVIAALVGGYALLGL--KIIGVVLNKVDGDNHGKLLKEAL---EELLRGLPVLGVIPRDEAVAEAPARGL 226
FlhG-like cd02038
MinD-like ATPase FlhG; FlhG is a member of the SIMIBI superfamily. FlhG (also known as YlxH) ...
 22-173 2.83e-17

MinD-like ATPase FlhG; FlhG is a member of the SIMIBI superfamily. FlhG (also known as YlxH) is a major determinant for a variety of flagellation patterns. It effects location and number of bacterial flagella during C-ring assembly.


Pssm-ID: 349758 [Multi-domain]  Cd Length: 230  Bit Score: 77.99  E-value: 2.83e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFG----------IEEKVyGSEEEIFpnKTGEGI 91
Cdd:cd02038    1 RIIAVTSGKGGVGKTNVSANLALALSKLGKRVLLLDADLGLANLDILLGlapkktlgdvLKGRV-SLEDIIV--EGPEGL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  92 KVMS--------INLmlpnktDPVIWRGPI--LSNILNDFwtkmnwgdlDFLLLDMPPGTGDVPLTIYQhyPVDGVVVVS 161
Cdd:cd02038   78 DIIPggsgmeelANL------DPEQKAKLIeeLSSLESNY---------DYLLIDTGAGISRNVLDFLL--AADEVIVVT 140

                        170
                 ....*....|....*
gi 736533368 162 TP---SKMASIAVLK 173
Cdd:cd02038  141 TPeptSITDAYALIK 155
ParA COG1192
ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein ...
 22-148 1.40e-12

ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ [Cell cycle control, cell division, chromosome partitioning, Cell motility];


Pssm-ID: 440805 [Multi-domain]  Cd Length: 253  Bit Score: 65.65  E-value: 1.40e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCD----LTgpsipEIFGIEEK-----VYG------SEEEIFPNK 86
Cdd:COG1192    2 KVIAVANQKGGVGKTTTAVNLAAALARRGKRVLLIDLDpqgnLT-----SGLGLDPDdldptLYDlllddaPLEDAIVPT 76

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 736533368  87 TGEGIKVM--SINLM-----LPNKTDpviwRGPILSNILNDFwtkmnWGDLDFLLLDMPPGTGdvPLTI 148
Cdd:COG1192   77 EIPGLDLIpaNIDLAgaeieLVSRPG----RELRLKRALAPL-----ADDYDYILIDCPPSLG--LLTL 134
MinD cd02036
septum site-determining protein MinD; Septum site-determining protein MinD is part of the ...
 22-252 2.45e-12

septum site-determining protein MinD; Septum site-determining protein MinD is part of the operon MinCDE that determines the site of the formation of a septum at mid-cell, an important part of bacterial cell division. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal role, selecting the mid-cell over other sites through the activation and regulation of MinC and MinE. MinD is a membrane-associated ATPase, related to nitrogenase iron protein.


Pssm-ID: 349756 [Multi-domain]  Cd Length: 236  Bit Score: 64.53  E-value: 2.45e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKVYGS-----------EEEIFPNKTGEG 90
Cdd:cd02036    1 RVIVITSGKGGVGKTTTTANLGVALAKLGKKVLLIDADIGLRNLDLILGLENRIVYTlvdvlegecrlEQALIKDKRWEN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  91 IKVMSINLML-PNKTDPVIWRgPILSNILNDFwtkmnwgdlDFLLLDMPPGTGdvplTIYQH--YPVDGVVVVSTPskma 167
Cdd:cd02036   81 LYLLPASQTRdKDALTPEKLE-ELVKELKDSF---------DFILIDSPAGIE----SGFINaiAPADEAIIVTNP---- 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368 168 siavlkayEM-ALRLNQNVIGEIENMSY---------YECKECGHKEYL-FGEKEHIEGLDMLGQVPFDPELGRFIDDG- 235
Cdd:cd02036  143 --------EIsSVRDADRVIGLLESKGIvniglivnrYRPEMVKSGDMLsVEDIQEILGIPLLGVIPEDPEVIVATNRGe 214

                        250       260
                 ....*....|....*....|..
gi 736533368 236 -----KIEDTYVMAYDEIVQKI 252
Cdd:cd02036  215 plvlyKPNSLAAKAFENIARRL 236
FlhG COG0455
MinD-like ATPase FlhG/YlxH, activator of the FlhF-type GTPase [Cell cycle control, cell ...
 38-252 1.21e-11

MinD-like ATPase FlhG/YlxH, activator of the FlhF-type GTPase [Cell cycle control, cell division, chromosome partitioning, Cell motility];


Pssm-ID: 440223 [Multi-domain]  Cd Length: 230  Bit Score: 62.60  E-value: 1.21e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  38 TTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKV--------YGSEEEIFpNKTGEGIKVmsinlmLPNKTDPVIW 109
Cdd:COG0455    2 VAVNLAAALARLGKRVLLVDADLGLANLDVLLGLEPKAtladvlagEADLEDAI-VQGPGGLDV------LPGGSGPAEL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368 110 RGPILSNILNDFWTKMNwGDLDFLLLDMPPGTGDVPLTIYQHypVDGVVVVSTPSkMASI----AVLKAyeMALRLNQNV 185
Cdd:COG0455   75 AELDPEERLIRVLEELE-RFYDVVLVDTGAGISDSVLLFLAA--ADEVVVVTTPE-PTSItdayALLKL--LRRRLGVRR 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 736533368 186 IGEIENMsyyeCKECGHKEYLFGE-----KEHIEG-LDMLGQVPFDPELGRFIDDGKI------EDTYVMAYDEIVQKI 252
Cdd:COG0455  149 AGVVVNR----VRSEAEARDVFERleqvaERFLGVrLRVLGVIPEDPAVREAVRRGRPlvlaapDSPAARAIRELAARL 223
ParAB_family cd02042
partition proteins ParAB family; ParA and ParB of Caulobacter crescentus belong to a conserved ...
 22-59 2.64e-11

partition proteins ParAB family; ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.


Pssm-ID: 349760 [Multi-domain]  Cd Length: 130  Bit Score: 59.48  E-value: 2.64e-11
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCD 59
Cdd:cd02042    1 KVIAVANQKGGVGKTTLAVNLAAALALRGKRVLLIDLD 38
minD CHL00175
septum-site determining protein; Validated
 14-226 2.81e-11

septum-site determining protein; Validated


Pssm-ID: 214385 [Multi-domain]  Cd Length: 281  Bit Score: 62.10  E-value: 2.81e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  14 ENKLSNIKRVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKVYGSEEEIFpnktgEGIKV 93
Cdd:CHL00175   8 KEKSATMSRIIVITSGKGGVGKTTTTANLGMSIARLGYRVALIDADIGLRNLDLLLGLENRVLYTAMDVL-----EGECR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  94 MSINLmLPNKTDPVIWRGPILSNILNDFWTKMNWGDL---------DFLLLDMPPGTgDVPLTIYQHyPVDGVVVVSTPS 164
Cdd:CHL00175  83 LDQAL-IRDKRWKNLSLLAISKNRQRYNVTRKNMNMLvdslknrgyDYILIDCPAGI-DVGFINAIA-PAQEAIVVTTPE 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 736533368 165 KMA------SIAVLKA---YEMAL---RLNQNVIGEIENMSYYECKEcghkeylfgekehIEGLDMLGQVPFDP 226
Cdd:CHL00175 160 ITAirdadrVAGLLEAngiYNVKLlvnRVRPDMIQANDMMSVRDVQE-------------MLGIPLLGAIPEDE 220
CooC1 cd02034
accessory protein CooC1; The accessory protein CooC1, a nickel-binding ATPase, participates in ...
 22-252 1.04e-10

accessory protein CooC1; The accessory protein CooC1, a nickel-binding ATPase, participates in the incorporation of nickel into the complex active site ([Ni-4Fe-4S]) cluster of Ni,Fe-dependent carbon monoxide dehydrogenase (CODH). CODH from Rhodospirillum rubrum catalyzes the reversible oxidation of CO to CO2. CODH contains a nickel-iron-sulfur cluster (C-center) and an iron-sulfur cluster (B-center). CO oxidation occurs at the C-center. Three accessory proteins encoded by cooCTJ genes are involved in nickel incorporation into a nickel site. CooC functions as a nickel insertase that mobilizes nickel to apoCODH using energy released from ATP hydrolysis. CooC is a homodimer and has NTPase activities. Mutation at the P-loop abolishs its function.


Pssm-ID: 349754 [Multi-domain]  Cd Length: 249  Bit Score: 60.02  E-value: 1.04e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  22 RVIAVTsGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDlTGPSIPEIFG--IEEKVYGSEEEIFPNKTGEGIKVMSINLM 99
Cdd:cd02034    1 MKIAVA-GKGGVGKTTIAALLIRYLAKKGGKVLAVDAD-PNSNLAETLGveVEKLPLIKTIGDIRERTGAKKGEPPEGMS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368 100 LPNKTDPVIWRGPI-----------------------LSNILNDFWTKMNWGDLDFLLLDMPPGTGDVPLTIYQHypVDG 156
Cdd:cd02034   79 LNPYVDDIIKEIIVepdgidllvmgrpegggsgcycpVNALLRELLRHLALKNYEYVVIDMEAGIEHLSRGTIRA--VDL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368 157 VVVVSTPSKMASIAVLKAYEMALRLNQNVIGEIENMSYYEckecGHKEYLfgeKEHIEGLDMLGQVPFDPELGRFIDDGK 236
Cdd:cd02034  157 LIIVIEPSKRSIQTAKRIKELAEELGIKKIYLIVNKVRNE----EEQELI---EELLIKLKLIGVIPYDEEIMEADLKGK 229

                        250       260
                 ....*....|....*....|
gi 736533368 237 ----IEDTYVMAYDEIVQKI 252
Cdd:cd02034  230 plfdLDSAAVKAIEKIVEKL 249
MinD COG2894
Septum site-determining ATPase MinD [Cell cycle control, cell division, chromosome ...
 22-59 1.44e-10

Septum site-determining ATPase MinD [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442139 [Multi-domain]  Cd Length: 258  Bit Score: 59.69  E-value: 1.44e-10
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCD 59
Cdd:COG2894    3 KVIVVTSGKGGVGKTTTTANLGTALALLGKKVVLIDAD 40
eps_fam TIGR01007
capsular exopolysaccharide family; This model describes the capsular exopolysaccharide ...
 22-191 1.04e-09

capsular exopolysaccharide family; This model describes the capsular exopolysaccharide proteins in bacteria. The exopolysaccharide gene cluster consists of several genes which encode a number of proteins which regulate the exoploysaccharide biosynthesis(EPS). Atleast 13 genes espA to espM in streptococcus species seem to direct the EPS proteins and all of which share high homology. Functional roles were characterized by gene disruption experiments which resulted in exopolysaccharide-deficient phenotypes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273392 [Multi-domain]  Cd Length: 204  Bit Score: 56.68  E-value: 1.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368   22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKVYGSEEEIFPNKT-GEGIKVMSI-NLM 99
Cdd:TIGR01007  18 KVLLITSVKPGEGKSTTSANIAIAFAQAGYKTLLIDGDMRNSVMSGTFKSQNKITGLTNFLSGTTDlSDAICDTNIeNLD 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  100 lpnktdpVIWRGPILSN----ILNDFWTKM-----NWgdLDFLLLDMPPGTGDVPLTIYQHYpVDGVVVVSTPSKMASIA 170
Cdd:TIGR01007  98 -------VITAGPVPPNptelLQSSNFKTLietlrKR--FDYIIIDTPPIGTVTDAAIIARA-CDASILVTDAGKIKKRE 167

                         170       180
                  ....*....|....*....|.
gi 736533368  171 VLKAYEMALRLNQNVIGEIEN 191
Cdd:TIGR01007 168 VKKAKEQLEQAGSNFLGVVLN 188
AAA_31 pfam13614
AAA domain; This family includes a wide variety of AAA domains including some that have lost ...
 22-139 4.70e-09

AAA domain; This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.


Pssm-ID: 433350 [Multi-domain]  Cd Length: 177  Bit Score: 54.51  E-value: 4.70e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368   22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCD-----LTGPSIpEIFGIEEKVY------GSEEEIFPNKTGEG 90
Cdd:pfam13614   2 KVIAIANQKGGVGKTTTSVNLAAALAKKGKKVLLIDLDpqgnaTSGLGI-DKNNVEKTIYelligeCNIEEAIIKTVIEN 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 736533368   91 IKVM--SINLM-LPNKTDPVIWRGPILSNILNDFwtKMNWgdlDFLLLDMPP 139
Cdd:pfam13614  81 LDLIpsNIDLAgAEIELIGIENRENILKEALEPV--KDNY---DYIIIDCPP 127
minD_bact TIGR01968
septum site-determining protein MinD; This model describes the bacterial and chloroplast form ...
 22-75 1.39e-08

septum site-determining protein MinD; This model describes the bacterial and chloroplast form of MinD, a multifunctional cell division protein that guides correct placement of the septum. The homologous archaeal MinD proteins, with many archaeal genomes having two or more forms, are described by a separate model. [Cellular processes, Cell division]


Pssm-ID: 131023 [Multi-domain]  Cd Length: 261  Bit Score: 54.27  E-value: 1.39e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 736533368   22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKV 75
Cdd:TIGR01968   2 RVIVITSGKGGVGKTTTTANLGTALARLGKKVVLIDADIGLRNLDLLLGLENRI 55
CooC COG3640
CO dehydrogenase nickel-insertion accessory protein CooC1 [Posttranslational modification, ...
 24-252 1.87e-08

CO dehydrogenase nickel-insertion accessory protein CooC1 [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442857 [Multi-domain]  Cd Length: 249  Bit Score: 53.63  E-value: 1.87e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  24 IAVTsGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDlTGPSIPEIFGIEEKVYGSE------EEIFPNKTGEGIKVMSIN 97
Cdd:COG3640    3 IAVA-GKGGVGKTTLSALLARYLAEKGKPVLAVDAD-PNANLAEALGLEVEADLIKplgemrELIKERTGAPGGGMFKLN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  98 L---MLPNKTdpVIWRGPI------------------LSNILNDFWTKMNWGDLDFLLLDMPPG---------TGdvplt 147
Cdd:COG3640   81 PkvdDIPEEY--LVEGDGVdllvmgtieeggsgcycpENALLRALLNHLVLGNYEYVVVDMEAGiehlgrgtaEG----- 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368 148 iyqhypVDGVVVVSTPSKmASIAVLKAY-EMALRLNQNVIGEIENMsyyeCKECGHKEYLfgeKEHIeGLDMLGQVPFDP 226
Cdd:COG3640  154 ------VDLLLVVSEPSR-RSIETARRIkELAEELGIKKIYLVGNK----VREEEDEEFL---RELL-GLELLGFIPYDE 218

                        250       260       270
                 ....*....|....*....|....*....|..
gi 736533368 227 EL------GRFIDDGKiEDTYVMAYDEIVQKI 252
Cdd:COG3640  219 EVreadleGKPLLDLP-DSPAVAAVEEIAEKL 249
PRK10818 PRK10818
septum site-determining protein MinD;
22-75 3.84e-08

septum site-determining protein MinD;


Pssm-ID: 182756 [Multi-domain]  Cd Length: 270  Bit Score: 53.02  E-value: 3.84e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKV 75
Cdd:PRK10818   3 RIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFDIGLRNLDLIMGCERRV 56
BY-kinase cd05387
bacterial tyrosine-kinase; Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on ...
 22-191 6.46e-08

bacterial tyrosine-kinase; Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.


Pssm-ID: 349772 [Multi-domain]  Cd Length: 190  Bit Score: 51.42  E-value: 6.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTGPSIPEIFGIEEKV--------YGSEEEIFPNKTGEGIKV 93
Cdd:cd05387   20 KVIAVTSASPGEGKSTVAANLAVALAQSGKRVLLIDADLRRPSLHRLLGLPNEPglsevlsgQASLEDVIQSTNIPNLDV 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  94 MSINLMLPNKTDPViwRGPILSNILNDFwtkmnWGDLDFLLLDMPPGTGDVPLTIYQHYpVDGVVVV----STPSKmasi 169
Cdd:cd05387  100 LPAGTVPPNPSELL--SSPRFAELLEEL-----KEQYDYVIIDTPPVLAVADALILAPL-VDGVLLVvragKTRRR---- 167

                        170       180
                 ....*....|....*....|..
gi 736533368 170 AVLKAYEMALRLNQNVIGEIEN 191
Cdd:cd05387  168 EVKEALERLEQAGAKVLGVVLN 189
SIMIBI cd01983
SIMIBI (signal recognition particle, MinD and BioD)-class NTPases; SIMIBI (after signal ...
 22-59 9.38e-08

SIMIBI (signal recognition particle, MinD and BioD)-class NTPases; SIMIBI (after signal recognition particle, MinD, and BioD), consists of signal recognition particle (SRP) GTPases, the assemblage of MinD-like ATPases, which are involved in protein localization, chromosome partitioning, and membrane transport, and a group of metabolic enzymes with kinase or related phosphate transferase activity. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion.


Pssm-ID: 349751 [Multi-domain]  Cd Length: 107  Bit Score: 48.97  E-value: 9.38e-08
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCD 59
Cdd:cd01983    1 RVIAVTGGKGGVGKTTLAAALAVALAAKGYKVLLIDLD 38
Bchl-like cd02032
L-subunit of protochlorophyllide reductase; This family of proteins contains BchL and ChlL. ...
 23-84 3.12e-07

L-subunit of protochlorophyllide reductase; This family of proteins contains BchL and ChlL. Protochlorophyllide reductase catalyzes the reductive formation of chlorophyllide from protochlorophyllide during biosynthesis of chlorophylls and bacteriochlorophylls. Three genes, bchL, bchN and bchB, are involved in light-independent protochlorophyllide reduction in bacteriochlorophyll biosynthesis. In cyanobacteria, algae, and gymnosperms, three similar genes, chlL, chlN and chlB are involved in protochlorophyllide reduction during chlorophylls biosynthesis. BchL/chlL, bchN/chlN and bchB/chlB exhibit significant sequence similarity to the nifH, nifD and nifK subunits of nitrogenase, respectively. Nitrogenase catalyzes the reductive formation of ammonia from dinitrogen.


Pssm-ID: 349752  Cd Length: 267  Bit Score: 49.99  E-value: 3.12e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  23 VIAVTsGKGGVGKSVTTSLLATTLNKKGYKVGVLDCD--------LTGPSIPEIFGIEEKVYGSEEEIFP 84
Cdd:cd02032    2 VIAVY-GKGGIGKSTTSSNLSAAFAKRGKKVLQIGCDpkhdstftLTGFLIPTVIDVLQSVDFHYEEVWP 70
CpaE COG4963
Flp pilus assembly ATPase CpaE/TadZ, contains N-terminal REC/TadZ_N domain [Intracellular ...
 22-74 3.86e-07

Flp pilus assembly ATPase CpaE/TadZ, contains N-terminal REC/TadZ_N domain [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443989 [Multi-domain]  Cd Length: 358  Bit Score: 50.11  E-value: 3.86e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTL-NKKGYKVGVLDCDLTGPSIPEIFGIEEK 74
Cdd:COG4963  103 RVIAVVGAKGGVGATTLAVNLAWALaRESGRRVLLVDLDLQFGDVALYLDLEPR 156
chlL PRK13185
protochlorophyllide reductase iron-sulfur ATP-binding protein; Provisional
 22-84 4.73e-07

protochlorophyllide reductase iron-sulfur ATP-binding protein; Provisional


Pssm-ID: 237293  Cd Length: 270  Bit Score: 49.58  E-value: 4.73e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 736533368  22 RVIAVTsGKGGVGKSVTTSLLATTLNKKGYKVGVLDCD--------LTGPSIPEIFGIEEKVYGSEEEIFP 84
Cdd:PRK13185   3 LVLAVY-GKGGIGKSTTSSNLSAAFAKLGKKVLQIGCDpkhdstftLTGKLVPTVIDILEEVDFHSEELRP 72
ParA_partition NF041546
ParA family partition ATPase;
23-59 2.28e-05

ParA family partition ATPase;


Pssm-ID: 469431 [Multi-domain]  Cd Length: 202  Bit Score: 44.08  E-value: 2.28e-05
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 736533368  23 VIAVTSGKGGVGKSvTTSL-LATTLNKKGYKVGVLDCD 59
Cdd:NF041546   1 IIAVLNQKGGVGKT-TLAThLAAALARRGYRVLLVDAD 37
MipZ pfam09140
ATPase MipZ; MipZ is an ATPase that forms a complex with the chromosome partitioning protein ...
 22-60 5.89e-05

ATPase MipZ; MipZ is an ATPase that forms a complex with the chromosome partitioning protein ParB near the chromosomal origin of replication. It is responsible for the temporal and spatial regulation of FtsZ ring formation.


Pssm-ID: 401181 [Multi-domain]  Cd Length: 262  Bit Score: 43.21  E-value: 5.89e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 736533368   22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDL 60
Cdd:pfam09140   1 HVIVVGNEKGGSGKSTTAVHVAVALLYKGARVAAIDLDL 39
ArsA COG0003
Anion-transporting ATPase, ArsA/GET3 family [Inorganic ion transport and metabolism];
21-72 2.51e-04

Anion-transporting ATPase, ArsA/GET3 family [Inorganic ion transport and metabolism];


Pssm-ID: 439774  Cd Length: 299  Bit Score: 41.73  E-value: 2.51e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 736533368  21 KRVIAVTsGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDLTgPSIPEIFGIE 72
Cdd:COG0003    3 TRIIFFT-GKGGVGKTTVAAATALALAERGKRTLLVSTDPA-HSLGDVLGTE 52
SIMIBI_bact_arch cd03110
bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily ...
 24-83 3.63e-04

bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.


Pssm-ID: 349764 [Multi-domain]  Cd Length: 246  Bit Score: 40.83  E-value: 3.63e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 736533368  24 IAVTSGKGGVGKSVTTSLLATTLnkkgYKVGVLDCDLTGPSIPEIFGIEekvyGSEEEIF 83
Cdd:cd03110    2 IAVLSGKGGTGKTTITANLAVLL----YNVILVDCDVDAPNLHLLLGPE----PEEEEDF 53
ArsA_ATPase pfam02374
Anion-transporting ATPase; This Pfam family represents a conserved domain, which is sometimes ...
 22-98 6.93e-04

Anion-transporting ATPase; This Pfam family represents a conserved domain, which is sometimes repeated, in an anion-transporting ATPase. The ATPase is involved in the removal of arsenate, antimonite, and arsenate from the cell.


Pssm-ID: 396792  Cd Length: 302  Bit Score: 40.41  E-value: 6.93e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 736533368   22 RVIAVTsGKGGVGKSVTTSLLATTLNKKGYKVGVLDCDlTGPSIPEIFGIEEkvyGSEeeifPNKTGEGIKVMSINL 98
Cdd:pfam02374   2 RWIFFG-GKGGVGKTTVSAATAVQLSELGKKVLLISTD-PAHSLSDSFNQKF---GHE----PTKVKENLSAMEIDP 69
YjiA COG2403
Zn/Ni/Co-binding GTPase YjiA, predicted metallochaperone, CobW/Nha3/YciC family [Inorganic ion ...
 17-55 7.86e-04

Zn/Ni/Co-binding GTPase YjiA, predicted metallochaperone, CobW/Nha3/YciC family [Inorganic ion transport and metabolism];


Pssm-ID: 441959  Cd Length: 441  Bit Score: 40.21  E-value: 7.86e-04
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 736533368  17 LSNIKRVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGV 55
Cdd:COG2403  115 LKSSKPVIAVCAVRTGCGKSQTSRKVARILKERGLKVVV 153
PRK13869 PRK13869
plasmid-partitioning protein RepA; Provisional
 22-59 1.00e-03

plasmid-partitioning protein RepA; Provisional


Pssm-ID: 139929 [Multi-domain]  Cd Length: 405  Bit Score: 40.04  E-value: 1.00e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 736533368  22 RVIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCD 59
Cdd:PRK13869 122 QVIAVTNFKGGSGKTTTSAHLAQYLALQGYRVLAVDLD 159
PRK13230 PRK13230
nitrogenase reductase-like protein; Reviewed
 29-71 1.28e-03

nitrogenase reductase-like protein; Reviewed


Pssm-ID: 183903  Cd Length: 279  Bit Score: 39.37  E-value: 1.28e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 736533368  29 GKGGVGKSVTTSLLATTLNKKGYKVGVLDCD--------LTGPSIPEIFGI 71
Cdd:PRK13230   8 GKGGIGKSTTVCNIAAALAESGKKVLVVGCDpkadctrnLVGEKIPTVLDV 58
NifH cd02040
nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. ...
 22-59 1.31e-03

nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the mollybdenum-iron (alternatively, vanadium-iron or iron-iron) protein (commonly referred to as component 1), and the iron protein (commonly referred to as component 2). The iron protein is a homodimer, with an Fe4S4 cluster bound between the subunits and two ATP-binding domains. It supplies energy by ATP hydrolysis, and transfers electrons from reduced ferredoxin or flavodoxin to component 1 for the reduction of molecular nitrogen to ammonia.


Pssm-ID: 349759  Cd Length: 265  Bit Score: 39.42  E-value: 1.31e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 736533368  22 RVIAVTsGKGGVGKSVTTSLLATTLNKKGYKVGVLDCD 59
Cdd:cd02040    1 RQIAIY-GKGGIGKSTTASNLSAALAEMGKKVLHVGCD 37
Grc3 COG1341
Polynucleotide 5'-kinase, involved in rRNA processing [Translation, ribosomal structure and ...
 5-59 2.69e-03

Polynucleotide 5'-kinase, involved in rRNA processing [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440952  Cd Length: 353  Bit Score: 38.46  E-value: 2.69e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 736533368   5 GNNMPLEkWENKLSNI-----KRVIAVtsgkGGV--GKSVTTSLLATTLNKKGYKVGVLDCD 59
Cdd:COG1341   16 GEEVPEE-WEELLEEIlssgpGRIMVL----GPVdsGKSTLTTLLANKLLAEGLKVAIIDAD 72
ArsA cd02035
Arsenical pump-driving ATPase ArsA; ArsA ATPase functions as an efflux pump located on the ...
 22-53 2.94e-03

Arsenical pump-driving ATPase ArsA; ArsA ATPase functions as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents. The pump is composed of two subunits, the catalytic ArsA subunit and the membrane subunit ArsB, which are encoded by arsA and arsB genes, respectively. Arsenic efflux in bacteria is catalyzed by either ArsB alone or by ArsAB complex. The ATP-coupled pump, however, is more efficient. ArsA is composed of two homologous halves, A1 and A2, connected by a short linker sequence.


Pssm-ID: 349755 [Multi-domain]  Cd Length: 250  Bit Score: 38.26  E-value: 2.94e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 736533368  22 RVIAVTsGKGGVGKSVTTSLLATTLNKKGYKV 53
Cdd:cd02035    1 RIIFFG-GKGGVGKTTIAAATAVRLAEQGKRV 31
NifH-like cd02117
NifH family; This family contains the NifH (iron protein) of nitrogenase, L subunit (BchL/ChlL) ...
 22-81 3.32e-03

NifH family; This family contains the NifH (iron protein) of nitrogenase, L subunit (BchL/ChlL) of the protochlorophyllide reductase, and the BchX subunit of the Chlorophyllide reductase. Members of this family use energy from ATP hydrolysis and transfer electrons through a Fe4-S4 cluster to other subunit for substrate reduction


Pssm-ID: 349761  Cd Length: 266  Bit Score: 38.12  E-value: 3.32e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 736533368  22 RVIAVTsGKGGVGKSVTTSLLATTLNKKGYKVGVLDCD--------LTGPSIPEIFGIEEKVYGSEEE 81
Cdd:cd02117    1 ESIVVY-GKGGIGKSTTASNLSAALAEGGKKVLHVGCDpkhdstllLTGGKVPPTIDEMLTEDGTAEE 67
TraL cd05386
transfer origin protein TraL; The transfer origin protein TraL is member of the SIMIBI ...
 26-59 5.22e-03

transfer origin protein TraL; The transfer origin protein TraL is member of the SIMIBI superfamily which contains a ATP-binding domain. Proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion. The specific function of TraL protein is unknown.


Pssm-ID: 349771  Cd Length: 155  Bit Score: 36.55  E-value: 5.22e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 736533368  26 VTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCD 59
Cdd:cd05386    5 VLQGKGGVGKSVIASLLAQYLIDKGQPVSCIDTD 38
chlL CHL00072
photochlorophyllide reductase subunit L
 29-68 6.09e-03

photochlorophyllide reductase subunit L


Pssm-ID: 177011  Cd Length: 290  Bit Score: 37.41  E-value: 6.09e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 736533368  29 GKGGVGKSVTTSLLATTLNKKGYKVGVLDCD--------LTGPSIPEI 68
Cdd:CHL00072   7 GKGGIGKSTTSCNISIALARRGKKVLQIGCDpkhdstftLTGFLIPTI 54
cellulose_yhjQ TIGR03371
cellulose synthase operon protein YhjQ; Members of this family are the YhjQ protein, found ...
 23-59 8.66e-03

cellulose synthase operon protein YhjQ; Members of this family are the YhjQ protein, found immediately upsteam of bacterial cellulose synthase (bcs) genes in a broad range of bacteria, including both copies of the bcs locus in Klebsiella pneumoniae. In several species it is seen clearly as part of the bcs operon. It is identified as a probable component of the bacterial cellulose metabolic process not only by gene location, but also by partial phylogenetic profiling, or Haft-Selengut algorithm (), based on a bacterial cellulose biosynthesis genome property profile. Cellulose plays an important role in biofilm formation and structural integrity in some bacteria. Mutants in yhjQ in Escherichia coli, show altered morphology an growth, but the function of YhjQ has not yet been determined. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274549 [Multi-domain]  Cd Length: 246  Bit Score: 36.55  E-value: 8.66e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 736533368   23 VIAVTSGKGGVGKSVTTSLLATTLNKKGYKVGVLDCD 59
Cdd:TIGR03371   3 VIAIVSVRGGVGKTTLTANLASALKLLGEPVLAIDLD 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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