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Conserved domains on  [gi|736642114|ref|WP_034649864|]
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alpha/beta fold hydrolase [Priestia megaterium]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 11426811)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

PubMed:  1409539|12369917

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 14-277 2.20e-57

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 183.28  E-value: 2.20e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  14 IELYYEDHG-TGKPVVLIHGWPLSGRSWEYQVPALvEAGYRVITYDRRGFGKSSQPWDGYDYETFAADLHQLLEHLDLTN 92
Cdd:COG0596   12 VRLHYREAGpDGPPVVLLHGLPGSSYEWRPLIPAL-AAGYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAALLDALGLER 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  93 VTLVGFSMGGGeVARYIGTYGTDRVEKAVfagavppflyksedhpegalddagiqefengvkndrlaflddftktffgve 172
Cdd:COG0596   91 VVLVGHSMGGM-VALELAARHPERVAGLV--------------------------------------------------- 118

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114 173 dgndLVSEPFRLYNRDIAA-AASPKGTLDCIAAFSKTDFRDDLAKFTIPTLIIHGDADEIVPFEYsGKRTYEAISGSKLA 251
Cdd:COG0596  119 ----LVDEVLAALAEPLRRpGLAPEALAALLRALARTDLRERLARITVPTLVIWGEKDPIVPPAL-ARRLAELLPNAELV 193

                        250       260
                 ....*....|....*....|....*.
gi 736642114 252 LIKGGPHGLNATHAHEFNEALLSFLR 277
Cdd:COG0596  194 VLPGAGHFPPLEQPEAFAAALRDFLA 219
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 14-277 2.20e-57

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 183.28  E-value: 2.20e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  14 IELYYEDHG-TGKPVVLIHGWPLSGRSWEYQVPALvEAGYRVITYDRRGFGKSSQPWDGYDYETFAADLHQLLEHLDLTN 92
Cdd:COG0596   12 VRLHYREAGpDGPPVVLLHGLPGSSYEWRPLIPAL-AAGYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAALLDALGLER 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  93 VTLVGFSMGGGeVARYIGTYGTDRVEKAVfagavppflyksedhpegalddagiqefengvkndrlaflddftktffgve 172
Cdd:COG0596   91 VVLVGHSMGGM-VALELAARHPERVAGLV--------------------------------------------------- 118

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114 173 dgndLVSEPFRLYNRDIAA-AASPKGTLDCIAAFSKTDFRDDLAKFTIPTLIIHGDADEIVPFEYsGKRTYEAISGSKLA 251
Cdd:COG0596  119 ----LVDEVLAALAEPLRRpGLAPEALAALLRALARTDLRERLARITVPTLVIWGEKDPIVPPAL-ARRLAELLPNAELV 193

                        250       260
                 ....*....|....*....|....*.
gi 736642114 252 LIKGGPHGLNATHAHEFNEALLSFLR 277
Cdd:COG0596  194 VLPGAGHFPPLEQPEAFAAALRDFLA 219
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 25-233 9.88e-37

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 130.70  E-value: 9.88e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   25 KPVVLIHGWPLSGRSWEYQVPALVEAGYRVITYDRRGFGKSSQPWDGYDYET--FAADLHQLLEHLDLTNVTLVGFSMGG 102
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQDDYRTddLAEDLEYILEALGLEKVNLVGHSMGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  103 GEVARYIGTYgTDRVEKAVFAGAV-PPFLYKSEDHPEGALDDAGIQEFENGVKNDRLAFLDDFTKTFFGVEDGNDLVSEP 181
Cdd:pfam00561  81 LIALAYAAKY-PDRVKALVLLGALdPPHELDEADRFILALFPGFFDGFVADFAPNPLGRLVAKLLALLLLRLRLLKALPL 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 736642114  182 F--RLYNRDIAAAASPK-GTLDCIAAFSKTDFRDDLAKFTIPTLIIHGDADEIVP 233
Cdd:pfam00561 160 LnkRFPSGDYALAKSLVtGALLFIETWSTELRAKFLGRLDEPTLIIWGDQDPLVP 214
protocat_pcaD TIGR02427
3-oxoadipate enol-lactonase; Members of this family are 3-oxoadipate enol-lactonase. Note that ...
 15-277 2.21e-28

3-oxoadipate enol-lactonase; Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other]


Pssm-ID: 131480 [Multi-domain]  Cd Length: 251  Bit Score: 108.98  E-value: 2.21e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   15 ELYYEDHG--TGKPV-VLIHGWPLSGRSWEYQVPALvEAGYRVITYDRRGFGKSSQPWDGYDYETFAADLHQLLEHLDLT 91
Cdd:TIGR02427   1 RLHYRLDGaaDGAPVlVFINSLGTDLRMWDPVLPAL-TPDFRVLRYDKRGHGLSDAPEGPYSIEDLADDVLALLDHLGIE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   92 NVTLVGFSMGGgEVARYIGTYGTDRVEKAVFAGAVPPF---------LYKSEDHPEGALDDAGIQEFengvkndrlaFLD 162
Cdd:TIGR02427  80 RAVFCGLSLGG-LIAQGLAARRPDRVRALVLSNTAAKIgtpeswnarIAAVRAEGLAALADAVLERW----------FTP 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  163 DFTktffgvedgndlVSEPFRLYN-RDIAAAASPKGTLDCIAAFSKTDFRDDLAKFTIPTLIIHGDADEIVPFEYsGKRT 241
Cdd:TIGR02427 149 GFR------------EAHPARLDLyRNMLVRQPPDGYAGCCAAIRDADFRDRLGAIAVPTLCIAGDQDGSTPPEL-VREI 215

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 736642114  242 YEAISGSKLALIKGGPHGLNATHAHEFNEALLSFLR 277
Cdd:TIGR02427 216 ADLVPGARFAEIRGAGHIPCVEQPEAFNAALRDFLR 251
PRK00870 PRK00870
haloalkane dehalogenase; Provisional
 11-102 6.56e-15

haloalkane dehalogenase; Provisional


Pssm-ID: 179147 [Multi-domain]  Cd Length: 302  Bit Score: 73.08  E-value: 6.56e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  11 EAPIELYYEDHGT--GKPVVLIHGWPlsgrSWEY----QVPALVEAGYRVITYDRRGFGKSSQPWD--GYDYETFAADLH 82
Cdd:PRK00870  31 GGPLRMHYVDEGPadGPPVLLLHGEP----SWSYlyrkMIPILAAAGHRVIAPDLIGFGRSDKPTRreDYTYARHVEWMR 106

                         90       100
                 ....*....|....*....|
gi 736642114  83 QLLEHLDLTNVTLVGFSMGG 102
Cdd:PRK00870 107 SWFEQLDLTDVTLVCQDWGG 126
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 14-277 2.20e-57

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 183.28  E-value: 2.20e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  14 IELYYEDHG-TGKPVVLIHGWPLSGRSWEYQVPALvEAGYRVITYDRRGFGKSSQPWDGYDYETFAADLHQLLEHLDLTN 92
Cdd:COG0596   12 VRLHYREAGpDGPPVVLLHGLPGSSYEWRPLIPAL-AAGYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAALLDALGLER 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  93 VTLVGFSMGGGeVARYIGTYGTDRVEKAVfagavppflyksedhpegalddagiqefengvkndrlaflddftktffgve 172
Cdd:COG0596   91 VVLVGHSMGGM-VALELAARHPERVAGLV--------------------------------------------------- 118

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114 173 dgndLVSEPFRLYNRDIAA-AASPKGTLDCIAAFSKTDFRDDLAKFTIPTLIIHGDADEIVPFEYsGKRTYEAISGSKLA 251
Cdd:COG0596  119 ----LVDEVLAALAEPLRRpGLAPEALAALLRALARTDLRERLARITVPTLVIWGEKDPIVPPAL-ARRLAELLPNAELV 193

                        250       260
                 ....*....|....*....|....*.
gi 736642114 252 LIKGGPHGLNATHAHEFNEALLSFLR 277
Cdd:COG0596  194 VLPGAGHFPPLEQPEAFAAALRDFLA 219
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 25-233 9.88e-37

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 130.70  E-value: 9.88e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   25 KPVVLIHGWPLSGRSWEYQVPALVEAGYRVITYDRRGFGKSSQPWDGYDYET--FAADLHQLLEHLDLTNVTLVGFSMGG 102
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQDDYRTddLAEDLEYILEALGLEKVNLVGHSMGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  103 GEVARYIGTYgTDRVEKAVFAGAV-PPFLYKSEDHPEGALDDAGIQEFENGVKNDRLAFLDDFTKTFFGVEDGNDLVSEP 181
Cdd:pfam00561  81 LIALAYAAKY-PDRVKALVLLGALdPPHELDEADRFILALFPGFFDGFVADFAPNPLGRLVAKLLALLLLRLRLLKALPL 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 736642114  182 F--RLYNRDIAAAASPK-GTLDCIAAFSKTDFRDDLAKFTIPTLIIHGDADEIVP 233
Cdd:pfam00561 160 LnkRFPSGDYALAKSLVtGALLFIETWSTELRAKFLGRLDEPTLIIWGDQDPLVP 214
protocat_pcaD TIGR02427
3-oxoadipate enol-lactonase; Members of this family are 3-oxoadipate enol-lactonase. Note that ...
 15-277 2.21e-28

3-oxoadipate enol-lactonase; Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other]


Pssm-ID: 131480 [Multi-domain]  Cd Length: 251  Bit Score: 108.98  E-value: 2.21e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   15 ELYYEDHG--TGKPV-VLIHGWPLSGRSWEYQVPALvEAGYRVITYDRRGFGKSSQPWDGYDYETFAADLHQLLEHLDLT 91
Cdd:TIGR02427   1 RLHYRLDGaaDGAPVlVFINSLGTDLRMWDPVLPAL-TPDFRVLRYDKRGHGLSDAPEGPYSIEDLADDVLALLDHLGIE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   92 NVTLVGFSMGGgEVARYIGTYGTDRVEKAVFAGAVPPF---------LYKSEDHPEGALDDAGIQEFengvkndrlaFLD 162
Cdd:TIGR02427  80 RAVFCGLSLGG-LIAQGLAARRPDRVRALVLSNTAAKIgtpeswnarIAAVRAEGLAALADAVLERW----------FTP 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  163 DFTktffgvedgndlVSEPFRLYN-RDIAAAASPKGTLDCIAAFSKTDFRDDLAKFTIPTLIIHGDADEIVPFEYsGKRT 241
Cdd:TIGR02427 149 GFR------------EAHPARLDLyRNMLVRQPPDGYAGCCAAIRDADFRDRLGAIAVPTLCIAGDQDGSTPPEL-VREI 215

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 736642114  242 YEAISGSKLALIKGGPHGLNATHAHEFNEALLSFLR 277
Cdd:TIGR02427 216 ADLVPGARFAEIRGAGHIPCVEQPEAFNAALRDFLR 251
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
16-278 5.25e-25

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 99.31  E-value: 5.25e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  16 LYYEDHGTGKPVVLIHGWPLSGRSWEYQVPALVEAGYRVITYDRRGFGKSSQPW-DGYDYETFAADLHQLLEHLDL---T 91
Cdd:COG2267   20 RWRPAGSPRGTVVLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRgHVDSFDDYVDDLRAALDALRArpgL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  92 NVTLVGFSMGGGEVARYIGTYGtDRVEKAVFAGAvppflyksedhpegalddagiqefengvkndrlAFLDDftktffgv 171
Cdd:COG2267  100 PVVLLGHSMGGLIALLYAARYP-DRVAGLVLLAP---------------------------------AYRAD-------- 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114 172 edgnDLVSEPFRLYnRDIAAAaspkgtldciaafsktdfrDDLAKFTIPTLIIHGDADEIVPFEYSgKRTYEAISGSK-L 250
Cdd:COG2267  138 ----PLLGPSARWL-RALRLA-------------------EALARIDVPVLVLHGGADRVVPPEAA-RRLAARLSPDVeL 192

                        250       260
                 ....*....|....*....|....*....
gi 736642114 251 ALIKGGPH-GLNATHAHEFNEALLSFLRD 278
Cdd:COG2267  193 VLLPGARHeLLNEPAREEVLAAILAWLER 221
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
16-277 4.61e-21

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 88.92  E-value: 4.61e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  16 LYYEDHGTGKPVVL-IHGWPLS-GRSWEYQVPALVEAGYRVITYDRRGFGKSSQPWDGYDYETFAADLHQLLEH--LDLT 91
Cdd:COG1506   14 LYLPADGKKYPVVVyVHGGPGSrDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWGGDEVDDVLAAIDYLAARpyVDPD 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  92 NVTLVGFSMGGGEVARYIGTYgTDRvekavFAGAVppflyksedhpegalDDAGIQEFEngvknDRLAFLDDFTKTFFGV 171
Cdd:COG1506   94 RIGIYGHSYGGYMALLAAARH-PDR-----FKAAV---------------ALAGVSDLR-----SYYGTTREYTERLMGG 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114 172 EDGndlvsepfrlyNRDIAAAASPkgtldciaafsktdfRDDLAKFTIPTLIIHGDADEIVPFEYSgKRTYEAISG---- 247
Cdd:COG1506  148 PWE-----------DPEAYAARSP---------------LAYADKLKTPLLLIHGEADDRVPPEQA-ERLYEALKKagkp 200

                        250       260       270
                 ....*....|....*....|....*....|
gi 736642114 248 SKLALIKGGPHGLNATHAHEFNEALLSFLR 277
Cdd:COG1506  201 VELLVYPGEGHGFSGAGAPDYLERILDFLD 230
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 27-260 1.62e-18

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 82.26  E-value: 1.62e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   27 VVLIHGwpLSGRSWEYQ--VPALVEAGYRVITYDRRGFGKsSQPWDGY--DYETFAADLHQLLEHLDLTN----VTLVGF 98
Cdd:pfam12146   7 VVLVHG--LGEHSGRYAhlADALAAQGFAVYAYDHRGHGR-SDGKRGHvpSFDDYVDDLDTFVDKIREEHpglpLFLLGH 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   99 SMGGGEVARYIGTYGtDRVEKAVFAGavpPFLYKSEDHPegalddagiqefeNGVKNDRLAFLDDFTKTF-FGVEDGNDL 177
Cdd:pfam12146  84 SMGGLIAALYALRYP-DKVDGLILSA---PALKIKPYLA-------------PPILKLLAKLLGKLFPRLrVPNNLLPDS 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  178 VS---EPFRLYNRD--IAAAASPKGTLDCIAAFSKTdfRDDLAKFTIPTLIIHGDADEIVPFEySGKRTYEAISGS--KL 250
Cdd:pfam12146 147 LSrdpEVVAAYAADplVHGGISARTLYELLDAGERL--LRRAAAITVPLLLLHGGADRVVDPA-GSREFYERAGSTdkTL 223

                         250
                  ....*....|
gi 736642114  251 ALIKGGPHGL 260
Cdd:pfam12146 224 KLYPGLYHEL 233
PRK00870 PRK00870
haloalkane dehalogenase; Provisional
 11-102 6.56e-15

haloalkane dehalogenase; Provisional


Pssm-ID: 179147 [Multi-domain]  Cd Length: 302  Bit Score: 73.08  E-value: 6.56e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  11 EAPIELYYEDHGT--GKPVVLIHGWPlsgrSWEY----QVPALVEAGYRVITYDRRGFGKSSQPWD--GYDYETFAADLH 82
Cdd:PRK00870  31 GGPLRMHYVDEGPadGPPVLLLHGEP----SWSYlyrkMIPILAAAGHRVIAPDLIGFGRSDKPTRreDYTYARHVEWMR 106

                         90       100
                 ....*....|....*....|
gi 736642114  83 QLLEHLDLTNVTLVGFSMGG 102
Cdd:PRK00870 107 SWFEQLDLTDVTLVCQDWGG 126
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 21-278 3.82e-14

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 71.51  E-value: 3.82e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  21 HGTGKPVVLIHGWPLSGRSWEYQVPALvEAGYRVITYDRRGFGKSSQPWDGYDYETFAADLHQLLEHLDLTNVTLVGFSM 100
Cdd:PRK14875 128 EGDGTPVVLIHGFGGDLNNWLFNHAAL-AAGRPVIALDLPGHGASSKAVGAGSLDELAAAVLAFLDALGIERAHLVGHSM 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114 101 GGGeVARYIGTYGTDRVekAVFAGAVPpflyksedhpegalddAGIQEFENGvkndrlafldDFTKTFFGVEDGNDL--- 177
Cdd:PRK14875 207 GGA-VALRLAARAPQRV--ASLTLIAP----------------AGLGPEING----------DYIDGFVAAESRRELkpv 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114 178 ----------VSEPF--------RLYNRD-----IAAAASPKGTldciaafSKTDFRDDLAKFTIPTLIIHGDADEIVPF 234
Cdd:PRK14875 258 lellfadpalVTRQMvedllkykRLDGVDdalraLADALFAGGR-------QRVDLRDRLASLAIPVLVIWGEQDRIIPA 330

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 736642114 235 EYSGkrtyEAISGSKLALIKGGPHGLNATHAHEFNEALLSFLRD 278
Cdd:PRK14875 331 AHAQ----GLPDGVAVHVLPGAGHMPQMEAAADVNRLLAEFLGK 370
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 16-278 7.94e-14

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 69.56  E-value: 7.94e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  16 LYYEDHGTGK-PVVLI-HGWplSG---RSWEYqVPALVEAGYRVITYDRRGFGKSSQPW------DGYDYETFAADLHQL 84
Cdd:COG1073   27 LYLPAGASKKyPAVVVaHGN--GGvkeQRALY-AQRLAELGFNVLAFDYRGYGESEGEPreegspERRDARAAVDYLRTL 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  85 LEHlDLTNVTLVGFSMGGGEVARYIGTYgtDRVeKAVfaGAVPPFlyksedhpegalddagiqefengvkNDRLAFLDDF 164
Cdd:COG1073  104 PGV-DPERIGLLGISLGGGYALNAAATD--PRV-KAV--ILDSPF-------------------------TSLEDLAAQR 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114 165 TKTFFGVEDGNDLVSEPFRLynrdiaaaaspkgtldciAAFSKTDFR--DDLAKFTIPTLIIHGDADEIVPFeYSGKRTY 242
Cdd:COG1073  153 AKEARGAYLPGVPYLPNVRL------------------ASLLNDEFDplAKIEKISRPLLFIHGEKDEAVPF-YMSEDLY 213

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 736642114 243 EAISGSK-LALIKGGPH-GLNATHAHEFNEALLSFLRD 278
Cdd:COG1073  214 EAAAEPKeLLIVPGAGHvDLYDRPEEEYFDKLAEFFKK 251
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 23-125 3.46e-13

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 64.47  E-value: 3.46e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  23 TGKPVVLIHGWPLSGRSWEYQVPALVEAGYRVITYDrrgfgkssQPWDGYDYETFAADLHQLLEHL----DLTNVTLVGF 98
Cdd:COG1075    4 TRYPVVLVHGLGGSAASWAPLAPRLRAAGYPVYALN--------YPSTNGSIEDSAEQLAAFVDAVlaatGAEKVDLVGH 75

                         90       100
                 ....*....|....*....|....*....
gi 736642114  99 SMGGGeVAR-YIGTY-GTDRVEKAVFAGA 125
Cdd:COG1075   76 SMGGL-VARyYLKRLgGAAKVARVVTLGT 103
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
22-277 1.20e-12

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 66.12  E-value: 1.20e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  22 GTGKPVVLIHGWPLSGRSWEYQVPALVEAGYRVITYDRRGFGKSSQPWDGYDYETFAADLHQLLEHLDLT--NVTLVGFS 99
Cdd:COG1647   13 GGRKGVLLLHGFTGSPAEMRPLAEALAKAGYTVYAPRLPGHGTSPEDLLKTTWEDWLEDVEEAYEILKAGydKVIVIGLS 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114 100 MGGGEVARYIGTYgtDRVEKAVFAGavPPFLYKSEDHPEgalddagiqefengvkndrLAFLDDFTKTFFGVEDGNDlvs 179
Cdd:COG1647   93 MGGLLALLLAARY--PDVAGLVLLS--PALKIDDPSAPL-------------------LPLLKYLARSLRGIGSDIE--- 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114 180 epfrlyNRDIAAAASPKGTLDCIAAFSK--TDFRDDLAKFTIPTLIIHGDADEIVPFEySGKRTYEAISGS--KLALIKG 255
Cdd:COG1647  147 ------DPEVAEYAYDRTPLRALAELQRliREVRRDLPKITAPTLIIQSRKDEVVPPE-SARYIYERLGSPdkELVWLED 219

                        250       260
                 ....*....|....*....|...
gi 736642114 256 GPHGL-NATHAHEFNEALLSFLR 277
Cdd:COG1647  220 SGHVItLDKDREEVAEEILDFLE 242
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 15-103 1.70e-12

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 66.17  E-value: 1.70e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  15 ELYYEDHGTGKPVVLIHGWPLSGRSWEYQVPALVEAGyRVITYDRRGFGKSSQPWDGYDYETFAADLHQLLEHLDLTNVT 94
Cdd:PRK03592  18 RMAYIETGEGDPIVFLHGNPTSSYLWRNIIPHLAGLG-RCLAPDLIGMGASDKPDIDYTFADHARYLDAWFDALGLDDVV 96


                 ....*....
gi 736642114  95 LVGFSMGGG 103
Cdd:PRK03592  97 LVGHDWGSA 105
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 27-271 7.96e-12

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 63.26  E-value: 7.96e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   27 VVLIHGWPLSgrswEYQVPALVEAGYRVITYDRRGFGKSSQPWDGYDyetFAADLHQLLEHL-DLTNVTLVGFSMGGGEV 105
Cdd:pfam12697   1 VVLVHGAGLS----AAPLAALLAAGVAVLAPDLPGHGSSSPPPLDLA---DLADLAALLDELgAARPVVLVGHSLGGAVA 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  106 ARYIGTYgtdRVEKAVFAGAVPPFlyksedhPEGALDDAGIQEFENGVKNDRLAFLDDFTKTFFGVEDgndlvsePFRLY 185
Cdd:pfam12697  74 LAAAAAA---LVVGVLVAPLAAPP-------GLLAALLALLARLGAALAAPAWLAAESLARGFLDDLP-------ADAEW 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  186 NRDIAAAASPKGTLDciaafskTDFRDDLAKFTIPTLIIHGDaDEIVPFEYsgKRTYEAISGSKLALIKGGPHGLNaTHA 265
Cdd:pfam12697 137 AAALARLAALLAALA-------LLPLAAWRDLPVPVLVLAEE-DRLVPELA--QRLLAALAGARLVVLPGAGHLPL-DDP 205


                  ....*.
gi 736642114  266 HEFNEA 271
Cdd:pfam12697 206 EEVAEA 211
COG4188 COG4188
Predicted dienelactone hydrolase [General function prediction only];
13-258 7.02e-10

Predicted dienelactone hydrolase [General function prediction only];


Pssm-ID: 443342 [Multi-domain]  Cd Length: 326  Bit Score: 58.58  E-value: 7.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  13 PIELYY-------EDHGTGKPVVLI-HGWPLSGRSWEYQVPALVEAGYRVI--------TYDRRGFGksSQPWDGYDYET 76
Cdd:COG4188   43 PVDVWYpatapadAPAGGPFPLVVLsHGLGGSREGYAYLAEHLASHGYVVAapdhpgsnAADLSAAL--DGLADALDPEE 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  77 F---AADLHQLLEHL--------------DLTNVTLVGFSMGGgevaryigtYGTdrvekAVFAGAVPpflyksedhpeg 139
Cdd:COG4188  121 LwerPLDLSFVLDQLlalnksdpplagrlDLDRIGVIGHSLGG---------YTA-----LALAGARL------------ 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114 140 alDDAGIQEFENGVKNDRLAFLDdftktffgvedgndlvSEPFRLYNRD--IAAAASpkgtldcIAAFSKTDF-RDDLAK 216
Cdd:COG4188  175 --DFAALRQYCGKNPDLQCRALD----------------LPRLAYDLRDprIKAVVA-------LAPGGSGLFgEEGLAA 229

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 736642114 217 FTIPTLIIHGDADEIVPFEYSGKRTYEAISGS--KLALIKGGPH 258
Cdd:COG4188  230 ITIPVLLVAGSADDVTPAPDEQIRPFDLLPGAdkYLLTLEGATH 273
PRK05855 PRK05855
SDR family oxidoreductase;
17-82 2.10e-09

SDR family oxidoreductase;


Pssm-ID: 235628 [Multi-domain]  Cd Length: 582  Bit Score: 57.68  E-value: 2.10e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 736642114  17 YYEDHGTGKP-VVLIHGWPLSGRSWEyQVPALVEAGYRVITYDRRGFGKSSQPWD--GYDYETFAADLH 82
Cdd:PRK05855  17 VYEWGDPDRPtVVLVHGYPDNHEVWD-GVAPLLADRFRVVAYDVRGAGRSSAPKRtaAYTLARLADDFA 84
PRK10673 PRK10673
esterase;
26-147 5.03e-07

esterase;


Pssm-ID: 182637 [Multi-domain]  Cd Length: 255  Bit Score: 49.73  E-value: 5.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  26 PVVLIHGwpLSGRSWEYQVPA--LVEAgYRVITYDRRGFGKSsqPWD-GYDYETFAADLHQLLEHLDLTNVTLVGFSMgG 102
Cdd:PRK10673  18 PIVLVHG--LFGSLDNLGVLArdLVND-HDIIQVDMRNHGLS--PRDpVMNYPAMAQDLLDTLDALQIEKATFIGHSM-G 91

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 736642114 103 GEVARYIGTYGTDRVEKAVfAGAVPPFLYKSEDHPE-----GALDDAGIQ 147
Cdd:PRK10673  92 GKAVMALTALAPDRIDKLV-AIDIAPVDYHVRRHDEifaaiNAVSEAGAT 140
PRK03204 PRK03204
haloalkane dehalogenase; Provisional
 16-102 7.19e-07

haloalkane dehalogenase; Provisional


Pssm-ID: 179554 [Multi-domain]  Cd Length: 286  Bit Score: 49.47  E-value: 7.19e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  16 LYYEDHGTGKPVVLIHGWPlsgrSWEYQVPALVEA---GYRVITYDRRGFGKSSQPWD-GYDYETFAADLHQLLEHLDLT 91
Cdd:PRK03204  26 IHYIDEGTGPPILLCHGNP----TWSFLYRDIIVAlrdRFRCVAPDYLGFGLSERPSGfGYQIDEHARVIGEFVDHLGLD 101

                         90
                 ....*....|.
gi 736642114  92 NVTLVGFSMGG 102
Cdd:PRK03204 102 RYLSMGQDWGG 112
PLN02980 PLN02980
2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate ...
 20-249 1.09e-06

2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate binding


Pssm-ID: 215530 [Multi-domain]  Cd Length: 1655  Bit Score: 49.86  E-value: 1.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   20 DHGTGKPVVLIHGWPLSGRSWeyqVPAL--VEAGYRVITYDRRGFGKS--------SQPWDGYDYETFAADLHQLLEHLD 89
Cdd:PLN02980 1367 QNAEGSVVLFLHGFLGTGEDW---IPIMkaISGSARCISIDLPGHGGSkiqnhakeTQTEPTLSVELVADLLYKLIEHIT 1443

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   90 LTNVTLVGFSMgGGEVARYIGTYGTDRVEKAVFAGAVPpflyksedhpegALDDAGIQEFENGVKNDRLAFLDD-----F 164
Cdd:PLN02980 1444 PGKVTLVGYSM-GARIALYMALRFSDKIEGAVIISGSP------------GLKDEVARKIRSAKDDSRARMLIDhgleiF 1510

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  165 TKTFFGVEDGNDLVSEP-------FRLYNRDIAAAASpkgTLDCIAAFSKTDFRDDLAKFTIPTLIIHGDADEivPFEYS 237
Cdd:PLN02980 1511 LENWYSGELWKSLRNHPhfnkivaSRLLHKDVPSLAK---LLSDLSIGRQPSLWEDLKQCDTPLLLVVGEKDV--KFKQI 1585

                         250
                  ....*....|..
gi 736642114  238 GKRTYEAISGSK 249
Cdd:PLN02980 1586 AQKMYREIGKSK 1597
PLN02578 PLN02578
hydrolase
 16-102 3.75e-06

hydrolase


Pssm-ID: 215315 [Multi-domain]  Cd Length: 354  Bit Score: 47.53  E-value: 3.75e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  16 LYYEDHGTGKPVVLIHGWPLSGRSWEYQVPALVEAgYRVITYDRRGFGKSSQPWDGYDYETFAADLHQLLEHLDLTNVTL 95
Cdd:PLN02578  78 IHYVVQGEGLPIVLIHGFGASAFHWRYNIPELAKK-YKVYALDLLGFGWSDKALIEYDAMVWRDQVADFVKEVVKEPAVL 156


                 ....*..
gi 736642114  96 VGFSMGG 102
Cdd:PLN02578 157 VGNSLGG 163
PLN03084 PLN03084
alpha/beta hydrolase fold protein; Provisional
 4-96 1.02e-05

alpha/beta hydrolase fold protein; Provisional


Pssm-ID: 178633  Cd Length: 383  Bit Score: 46.41  E-value: 1.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   4 INVGTENEAPIELY---YEDHGTGK--PVVLIHGWPLSGRSWEYQVPALVEaGYRVITYDRRGFGKSS--QPWDGYDYET 76
Cdd:PLN03084 102 LKMGAQSQASSDLFrwfCVESGSNNnpPVLLIHGFPSQAYSYRKVLPVLSK-NYHAIAFDWLGFGFSDkpQPGYGFNYTL 180

                         90       100
                 ....*....|....*....|..
gi 736642114  77 --FAADLHQLLEHLDLTNVTLV 96
Cdd:PLN03084 181 deYVSSLESLIDELKSDKVSLV 202
YheT COG0429
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
18-127 2.50e-05

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


Pssm-ID: 440198 [Multi-domain]  Cd Length: 323  Bit Score: 44.75  E-value: 2.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  18 YEDHGTGKP-VVLIHGWPLSGRSWeY---QVPALVEAGYRVITYDRRGFGK----------SSqpwDGYDYETFAADLHQ 83
Cdd:COG0429   54 SDPPAPSKPlVVLLHGLEGSSDSH-YargLARALYARGWDVVRLNFRGCGGepnllprlyhSG---DTEDLVWVLAHLRA 129

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 736642114  84 LLEHldlTNVTLVGFSMGGGEVARYIGTYGTDRVE-KAVFAGAVP 127
Cdd:COG0429  130 RYPY---APLYAVGFSLGGNLLLKYLGEQGDDAPPlKAAVAVSPP 171
COG2945 COG2945
Alpha/beta superfamily hydrolase [General function prediction only];
46-235 2.93e-05

Alpha/beta superfamily hydrolase [General function prediction only];


Pssm-ID: 442188 [Multi-domain]  Cd Length: 201  Bit Score: 44.00  E-value: 2.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  46 ALVEAGYRVITYDRRGFGKSSQPWDGYDYETFaaDLHQLLEHL---DLTNVTLVGFSMGGgevarYIGTygtdRVekavf 122
Cdd:COG2945   50 ALVAAGFAVLRFNFRGVGRSEGEFDEGRGELD--DAAAALDWLraqNPLPLWLAGFSFGA-----YVAL----QL----- 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114 123 AGAVPPflyksedhPEGALddagiqefengvkndrlaflddftktffgvedgndLVSEPFRLYnrdiaaaaspkgtldci 202
Cdd:COG2945  114 AMRLPE--------VEGLI-----------------------------------LVAPPVNRY----------------- 133

                        170       180       190
                 ....*....|....*....|....*....|...
gi 736642114 203 aafsktDFrDDLAKFTIPTLIIHGDADEIVPFE 235
Cdd:COG2945  134 ------DF-SFLAPCPAPTLVIHGEQDEVVPPA 159
PRK10349 PRK10349
pimeloyl-ACP methyl ester esterase BioH;
15-233 4.92e-05

pimeloyl-ACP methyl ester esterase BioH;


Pssm-ID: 137836 [Multi-domain]  Cd Length: 256  Bit Score: 43.85  E-value: 4.92e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  15 ELYYEDHGTGK-PVVLIHGWPLSGRSWeYQVPALVEAGYRVITYDRRGFGKSSqpwdGYDYETFAADLHQLLEHLDLTNV 93
Cdd:PRK10349   3 NIWWQTKGQGNvHLVLLHGWGLNAEVW-RCIDEELSSHFTLHLVDLPGFGRSR----GFGALSLADMAEAVLQQAPDKAI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  94 TLvGFSMgGGEVARYIGTYGTDRVEKAVFAGAVPPFLYKsEDHPegalddagiqefenGVKNDRLA-----FLDDFTKT- 167
Cdd:PRK10349  78 WL-GWSL-GGLVASQIALTHPERVQALVTVASSPCFSAR-DEWP--------------GIKPDVLAgfqqqLSDDFQRTv 140

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 736642114 168 --FFGVED-GNDLVSEPFRLYNRDIAAAASPK-----GTLDCIAAfskTDFRDDLAKFTIPTLIIHGDADEIVP 233
Cdd:PRK10349 141 erFLALQTmGTETARQDARALKKTVLALPMPEvdvlnGGLEILKT---VDLRQPLQNVSMPFLRLYGYLDGLVP 211
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
4-103 5.86e-05

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 43.42  E-value: 5.86e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   4 INVGTENEAPIELYYEDHGTGKP-VVLIHGWPLSGRSWEYQVPALVEAGYRVITYDRRGFGKSSQPWD-------GYDYE 75
Cdd:COG0412    8 IPTPDGVTLPGYLARPAGGGPRPgVVVLHEIFGLNPHIRDVARRLAAAGYVVLAPDLYGRGGPGDDPDearalmgALDPE 87

                         90       100       110
                 ....*....|....*....|....*....|....
gi 736642114  76 TFAADLHQLLEHL------DLTNVTLVGFSMGGG 103
Cdd:COG0412   88 LLAADLRAALDWLkaqpevDAGRVGVVGFCFGGG 121
PRK06489 PRK06489
hypothetical protein; Provisional
 24-102 1.23e-04

hypothetical protein; Provisional


Pssm-ID: 235815 [Multi-domain]  Cd Length: 360  Bit Score: 43.05  E-value: 1.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  24 GKPVVLIHGWPLSGRSW---EYQvPALVEAG-------YRVITYDRRGFGKSSQPWDG-------YDYETFAADLHQLL- 85
Cdd:PRK06489  69 DNAVLVLHGTGGSGKSFlspTFA-GELFGPGqpldaskYFIILPDGIGHGKSSKPSDGlraafprYDYDDMVEAQYRLVt 147

                         90
                 ....*....|....*...
gi 736642114  86 EHLDLTNVTLV-GFSMGG 102
Cdd:PRK06489 148 EGLGVKHLRLIlGTSMGG 165
PLN02679 PLN02679
hydrolase, alpha/beta fold family protein
 24-101 1.03e-03

hydrolase, alpha/beta fold family protein


Pssm-ID: 178283 [Multi-domain]  Cd Length: 360  Bit Score: 40.21  E-value: 1.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  24 GKPVVLIHGWPLSGRSWEYQVPALVEAgYRVITYDRRGFGKSSQPwDGYDY--ETFAADLHQLLEHLDLTNVTLVGFSMG 101
Cdd:PLN02679  88 GPPVLLVHGFGASIPHWRRNIGVLAKN-YTVYAIDLLGFGASDKP-PGFSYtmETWAELILDFLEEVVQKPTVLIGNSVG 165
BD-FAE pfam20434
BD-FAE; This family represents a novel bifunctional feruloyl and acetyl xylan esterase (BD-FAE, ...
 87-237 2.43e-03

BD-FAE; This family represents a novel bifunctional feruloyl and acetyl xylan esterase (BD-FAE, previously known as bifunctional carbohydrate esterase (CE)), which is active on complex natural xylans and was identified as the basis of a monophyletic clade gathering all homologs identified in PULs (polysaccharide utilization loci) predicted to act on xylan. It adopts an alpha-beta-hydrolase fold with the catalytic triad Ser-Asp-His. This new family of proteins is a new candidate for biomass processing due to its capacity to remove ferulic acid and acetic acid from natural corn and birchwood xylan substrates.


Pssm-ID: 466583 [Multi-domain]  Cd Length: 215  Bit Score: 38.32  E-value: 2.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114   87 HLDLTNVTLVGFSmGGGEVARYIGTYGTDRVekavFAGAVPPFLYKSEDHPE---GALDDAGIQEFengvkndrlafldd 163
Cdd:pfam20434  85 GIDTNKIALMGFS-AGGHLALLAGLSNNNKE----FEGNVGDYTPESSKESFkvnAVVDFYGPTDL-------------- 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  164 ftKTFFGVEDGNDLVSEPFRLY------NRDIAAAASPkgtldcIAAFSKTDfrddlakftIPTLIIHGDADEIVPFEYS 237
Cdd:pfam20434 146 --LDMDSCGTHNDAKSPETLLLgappleNPDLAKSASP------ITYVDKND---------PPFLIIHGDKDPLVPYCQS 208
PLN03087 PLN03087
BODYGUARD 1 domain containing hydrolase; Provisional
 20-90 6.47e-03

BODYGUARD 1 domain containing hydrolase; Provisional


Pssm-ID: 215567  Cd Length: 481  Bit Score: 37.87  E-value: 6.47e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 736642114  20 DHGTGKPVVLIHGWPLSGRSW-EYQVPALVEAG---YRVITYDRRGFGKSSQPWDgydyetfaaDLHQLLEHLDL 90
Cdd:PLN03087 197 DNKAKEDVLFIHGFISSSAFWtETLFPNFSDAAkstYRLFAVDLLGFGRSPKPAD---------SLYTLREHLEM 262
PLN02824 PLN02824
hydrolase, alpha/beta fold family protein
 17-102 7.91e-03

hydrolase, alpha/beta fold family protein


Pssm-ID: 178419 [Multi-domain]  Cd Length: 294  Bit Score: 37.03  E-value: 7.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  17 YYEDHGTGKPVVLIHGWPLSGRSWEYQVPALVEAGyRVITYDRRGFGKSSQP-------WDGYDYETFAADLHQLLEHLD 89
Cdd:PLN02824  22 YQRAGTSGPALVLVHGFGGNADHWRKNTPVLAKSH-RVYAIDLLGYGYSDKPnprsappNSFYTFETWGEQLNDFCSDVV 100

                         90
                 ....*....|...
gi 736642114  90 LTNVTLVGFSMGG 102
Cdd:PLN02824 101 GDPAFVICNSVGG 113
PRK11126 PRK11126
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional
 24-102 9.65e-03

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional


Pssm-ID: 236855 [Multi-domain]  Cd Length: 242  Bit Score: 36.74  E-value: 9.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736642114  24 GKP-VVLIHGWPLSGRSWEYQVPALveAGYRVITYDRRGFGKSsQPWDGYDYETFAADLHQLLEHLDLTNVTLVGFSMGG 102
Cdd:PRK11126   1 GLPwLVFLHGLLGSGQDWQPVGEAL--PDYPRLYIDLPGHGGS-AAISVDGFADVSRLLSQTLQSYNILPYWLVGYSLGG 77
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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