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Conserved domains on  [gi|736682565|ref|WP_034688455|]
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MULTISPECIES: recombination regulator RecX [Enterococcus]

Protein Classification

regulatory protein RecX( domain architecture ID 4708)

regulatory protein RecX modulates RecA activities (both recombinase and coprotease) through direct physical interaction

CATH:  1.10.10.10
Gene Ontology:  GO:0006282
PubMed:  18650935

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
recX super family cl00936
recombination regulator RecX; Reviewed
4-263 5.55e-91

recombination regulator RecX; Reviewed


The actual alignment was detected with superfamily member PRK14135:

Pssm-ID: 470000 [Multi-domain]  Cd Length: 263  Bit Score: 269.78  E-value: 5.55e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565   4 IARISKGKGpFYQIDLSDGETLQVSEDILVRYRLLKGQELTEDKLAEIKKSTGYDFGLQQALNYLSYQLRTEKEIRIYLK 83
Cdd:PRK14135   4 ITVQKKNKE-RYNIFLDEKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKEVRDYLK 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565  84 DKEIGQEDRHKIIEKLKGLGLVDDLTFGESYVRTNMRLSDKGPKKLAQQMQQKGLSPEVIEQSLSQYPFEEQVENARQTA 163
Cdd:PRK14135  83 KHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQKLA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565 164 EKTYEKNRAKSQKDLLRNIQQKLMTKGFTNDVIQEAMQTLPQETDPEAEYELLVQQGEKIWRKNSRFEPQKRKMKVKQGL 243
Cdd:PRK14135 163 EKLLKKYQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYSKYDGYELKQKLKQAL 242
                        250       260
                 ....*....|....*....|
gi 736682565 244 YQKGFDFEMIQRFILEKEEE 263
Cdd:PRK14135 243 YRKGFSYDDIDSFLREYGIE 262
 
Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
4-263 5.55e-91

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 269.78  E-value: 5.55e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565   4 IARISKGKGpFYQIDLSDGETLQVSEDILVRYRLLKGQELTEDKLAEIKKSTGYDFGLQQALNYLSYQLRTEKEIRIYLK 83
Cdd:PRK14135   4 ITVQKKNKE-RYNIFLDEKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKEVRDYLK 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565  84 DKEIGQEDRHKIIEKLKGLGLVDDLTFGESYVRTNMRLSDKGPKKLAQQMQQKGLSPEVIEQSLSQYPFEEQVENARQTA 163
Cdd:PRK14135  83 KHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQKLA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565 164 EKTYEKNRAKSQKDLLRNIQQKLMTKGFTNDVIQEAMQTLPQETDPEAEYELLVQQGEKIWRKNSRFEPQKRKMKVKQGL 243
Cdd:PRK14135 163 EKLLKKYQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYSKYDGYELKQKLKQAL 242
                        250       260
                 ....*....|....*....|
gi 736682565 244 YQKGFDFEMIQRFILEKEEE 263
Cdd:PRK14135 243 YRKGFSYDDIDSFLREYGIE 262
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
61-206 1.31e-37

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 129.52  E-value: 1.31e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565  61 LQQALNYLSYQLRTEKEIRIYLKDKEIGQEDRHKIIEKLKGLGLVDDLTFGESYVRTNMRLSDKGPKKLAQQMQQKGLSP 140
Cdd:COG2137    9 RNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQELRQKGIDE 88
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 736682565 141 EVIEQSLSQYPFEEQVENARQTAEKTYEKNRAKSQKDLLRNIQQKLMTKGFTNDVIQEAMQTLPQE 206
Cdd:COG2137   89 ELIEEALEELDEEDELEAARELARKKFGSLKPLDPAKEKQKLARFLARRGFSSDLIRRVLRELLEE 154
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
82-201 3.87e-29

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 106.90  E-value: 3.87e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565   82 LKDKEIGQEDRHKIIEKLKGLGLVDDLTFGESYVRTNMRLSDKGPKKLAQQMQQKGLSPEVIEQSLSQYPFEEQVenARQ 161
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFDEEEQI--ARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 736682565  162 TAEKTYEKNRAKSQKDLLRNIQQKLMTKGFTNDVIQEAMQ 201
Cdd:pfam02631  79 LAEKKFKRYPAESDRKLKQKLIRFLARRGFSSEVIRAALQ 118
 
Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
4-263 5.55e-91

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 269.78  E-value: 5.55e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565   4 IARISKGKGpFYQIDLSDGETLQVSEDILVRYRLLKGQELTEDKLAEIKKSTGYDFGLQQALNYLSYQLRTEKEIRIYLK 83
Cdd:PRK14135   4 ITVQKKNKE-RYNIFLDEKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKEVRDYLK 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565  84 DKEIGQEDRHKIIEKLKGLGLVDDLTFGESYVRTNMRLSDKGPKKLAQQMQQKGLSPEVIEQSLSQYPFEEQVENARQTA 163
Cdd:PRK14135  83 KHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQKLA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565 164 EKTYEKNRAKSQKDLLRNIQQKLMTKGFTNDVIQEAMQTLPQETDPEAEYELLVQQGEKIWRKNSRFEPQKRKMKVKQGL 243
Cdd:PRK14135 163 EKLLKKYQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYSKYDGYELKQKLKQAL 242
                        250       260
                 ....*....|....*....|
gi 736682565 244 YQKGFDFEMIQRFILEKEEE 263
Cdd:PRK14135 243 YRKGFSYDDIDSFLREYGIE 262
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
61-206 1.31e-37

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 129.52  E-value: 1.31e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565  61 LQQALNYLSYQLRTEKEIRIYLKDKEIGQEDRHKIIEKLKGLGLVDDLTFGESYVRTNMRLSDKGPKKLAQQMQQKGLSP 140
Cdd:COG2137    9 RNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQELRQKGIDE 88
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 736682565 141 EVIEQSLSQYPFEEQVENARQTAEKTYEKNRAKSQKDLLRNIQQKLMTKGFTNDVIQEAMQTLPQE 206
Cdd:COG2137   89 ELIEEALEELDEEDELEAARELARKKFGSLKPLDPAKEKQKLARFLARRGFSSDLIRRVLRELLEE 154
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
82-201 3.87e-29

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 106.90  E-value: 3.87e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565   82 LKDKEIGQEDRHKIIEKLKGLGLVDDLTFGESYVRTNMRLSDKGPKKLAQQMQQKGLSPEVIEQSLSQYPFEEQVenARQ 161
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFDEEEQI--ARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 736682565  162 TAEKTYEKNRAKSQKDLLRNIQQKLMTKGFTNDVIQEAMQ 201
Cdd:pfam02631  79 LAEKKFKRYPAESDRKLKQKLIRFLARRGFSSEVIRAALQ 118
recX PRK00117
recombination regulator RecX; Reviewed
64-206 2.22e-21

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 87.63  E-value: 2.22e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565  64 ALNYLSYQLRTEKEIRIYLKDKEIGQEDRHKIIEKLKGLGLVDDLTFGESYVRTNMRlSDKGPKKLAQQMQQKGLSPEVI 143
Cdd:PRK00117  17 ALRLLARREHSRAELRRKLAAKGFSEEVIEAVLDRLKEEGLLDDERFAESFVRSRAR-KGYGPRRIRQELRQKGVDREII 95
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 736682565 144 EQSLSQYPfEEQVENARQTAEKTYeKNRAKSQKDLLRNIQQKLMTKGFTNDVIQEAMQTLPQE 206
Cdd:PRK00117  96 EEALAELD-IDWEELARELARKKF-RRPLPDDAKEKAKLVRFLARRGFSMDVIQRVLRNALDD 156
recX PRK14134
recombination regulator RecX; Provisional
28-212 2.11e-09

recombination regulator RecX; Provisional


Pssm-ID: 184530 [Multi-domain]  Cd Length: 283  Bit Score: 56.74  E-value: 2.11e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565  28 SEDILVRYRLLKGQELTEDKLAEIKKSTGYDFGLQQALNYLSYQLRTEKEIRIYLKDKEIGQEDRHKIIEKLKGLGLVDD 107
Cdd:PRK14134  31 SAELVYYHNLKKGKVIDVNSLNDIIKEDNYIKCKGYALKYIEKSYKTEKQIKEKLYLKEYDEDAVNRVIRFLKEYNFIDD 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736682565 108 LTFGESYVRTNmrLSDKGPKKLAQQMQQKGLSPEVIEQSLSQYPFEEQVENARQTAEKTYE--KNRAKSQKDLLRNIQQK 185
Cdd:PRK14134 111 DKYCDMYIREK--INSYGRNKIKYTLLNKGIKENIIIEKINNIDEEKEKKVAYKLAEKKYKilILSEKNKFKIYKKLGPY 188
                        170       180
                 ....*....|....*....|....*..
gi 736682565 186 LMTKGFTNDVIQEAMQTLPQETDPEAE 212
Cdd:PRK14134 189 LISRGYSSNIAEWILNELIKNEALYKD 215
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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