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Conserved domains on  [gi|736904620|ref|WP_034903377|]
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S46 family peptidase [Erythrobacter litoralis]

Protein Classification

S46 family peptidase( domain architecture ID 12106229)

S46 family peptidase is a serine protease similar to Capnocytophaga gingivalis dipeptidyl-peptidase 7 and Asp/Glu-specific dipeptidyl-peptidase, which catalyze the removal of dipeptides from the N-terminus of oligopeptides

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Peptidase_S46 pfam10459
Peptidase S46; Dipeptidyl-peptidase 7 (DPP-7) is the best characterized member of this family. ...
 27-721 0e+00

Peptidase S46; Dipeptidyl-peptidase 7 (DPP-7) is the best characterized member of this family. It is a serine peptidase that is located on the cell surface and is predicted to have two N-terminal transmembrane domains.


:

Pssm-ID: 431297  Cd Length: 695  Bit Score: 890.07  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620   27 EGMFTPDQLQEIAGQLEEAGLEIEAEELADLTGFPMGAIVS-LGGCSASFVSPTGLVVTNHHCARGSVQYNSTADNNYLE 105
Cdd:pfam10459   2 EGMWTPQQLPEQADKLKALGLEIDAEWLYNLRRSSKDAVVRfGGGCTGSFVSPDGLVLTNHHCAYGAIQQHSSVEHDYLK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  106 NGFLANALAEELPAaPGSRIYVTTQVTDVTDRMRAGTE-GMEPYERYELVQQRSKDITAECEEDAGFRCQVASFYGGAEY 184
Cdd:pfam10459  82 DGFLAKSRAEELPA-PGLRVTVLVRITDVTDRVRAALKaGTDGEERSKAIEARLKALAKECEKEDGLRCEVVAFYGGNEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  185 KLIKRLEVRDVRLVYAPADSIGKYGGDIDNWMWPRHTGDFAFYRAYVAPDGSAADYAEENVPYEPEHHLKVSAAGLEEGD 264
Cdd:pfam10459 161 YLYKYREYKDVRLVFAPPSSIGKFGGDTDNWMWPRHTGDFSFFRAYAGKDGKPADYSKDNVPYKPKHFLKISLKGVKEGD 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  265 FVMAAGYPGSTSRYTLMAEVENTFGWTYPTFQTLLTDWIATIEEAAPQGTDARVKYESRLAGLNNFEKNLRGQIEGARRV 344
Cdd:pfam10459 241 FVFVAGYPGSTSRYLTSAEVEERRDWVNPARIDRRGERQALLEREMLKDPEIRIKYASKLAGSANYWKNLIGMLEGLRDL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  345 GLVERRREREEALAAWIAADPSRV-EYGKAIAELAELSEESAQASRTNFWYNNATRPA--LLGVAERLYRLSKERQKEDA 421
Cdd:pfam10459 321 DVLAKKQAREAALRAWLRKDPARRkKYGDALDELDALQAERRDLARRYYYFEEAFSGGseLLSAARTLVRLAKEREKPDA 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  422 QRESGYQERDMGFFRQGLQALDRRFDPAVDKAEWELFLTGYLAQPVDERVAVLDEALGITAdmtPADLPALLDRFYAETE 501
Cdd:pfam10459 401 EREPGYQERALPTLKKSLERIDADYDPEVDKAVLAAMLEEYRELLGADRLPAVDKLLGKEF---KGSPDAYADRLYAGSK 477

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  502 LDDAETRLALMEATPQQLEASDDPFIELAVALYDYGFQLETESKTRAGLALALRPAYMEAITGWQRESGVltYPDANSTL 581
Cdd:pfam10459 478 LTDPANRLALLEGGKAAVEASKDPMIALAVALADARRALEKAEKELDGAIERARPLYAKARLAMYGSTPV--YPDANSTL 555

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  582 RVTYGEVLGGSPRDGMAYYPFTTLEGITEK-DTGEDPFNAPQDLLDTIEARDYGPYKLEsIGSVPVNFLSDLDSTGGNSG 660
Cdd:pfam10459 556 RLTYGQVKGYSPRDGVYYPPFTTLDGVFEKeDTGEEPFDVPEKLLDAIEAKDFGRYAAE-NGSVPVNFLSTNDITGGNSG 634

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 736904620  661 SATLNARAELVGLLFDGTFESVNSDWDFDPRTTRTIHVDTRYMLWVMDKVDGAERLIEEMD 721
Cdd:pfam10459 635 SPVLNGKGELVGLAFDGNWESLSGDIGFDPDLQRAVAVDIRYILWALDKVYGADHLIDELT 695
 
Name Accession Description Interval E-value
Peptidase_S46 pfam10459
Peptidase S46; Dipeptidyl-peptidase 7 (DPP-7) is the best characterized member of this family. ...
 27-721 0e+00

Peptidase S46; Dipeptidyl-peptidase 7 (DPP-7) is the best characterized member of this family. It is a serine peptidase that is located on the cell surface and is predicted to have two N-terminal transmembrane domains.


Pssm-ID: 431297  Cd Length: 695  Bit Score: 890.07  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620   27 EGMFTPDQLQEIAGQLEEAGLEIEAEELADLTGFPMGAIVS-LGGCSASFVSPTGLVVTNHHCARGSVQYNSTADNNYLE 105
Cdd:pfam10459   2 EGMWTPQQLPEQADKLKALGLEIDAEWLYNLRRSSKDAVVRfGGGCTGSFVSPDGLVLTNHHCAYGAIQQHSSVEHDYLK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  106 NGFLANALAEELPAaPGSRIYVTTQVTDVTDRMRAGTE-GMEPYERYELVQQRSKDITAECEEDAGFRCQVASFYGGAEY 184
Cdd:pfam10459  82 DGFLAKSRAEELPA-PGLRVTVLVRITDVTDRVRAALKaGTDGEERSKAIEARLKALAKECEKEDGLRCEVVAFYGGNEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  185 KLIKRLEVRDVRLVYAPADSIGKYGGDIDNWMWPRHTGDFAFYRAYVAPDGSAADYAEENVPYEPEHHLKVSAAGLEEGD 264
Cdd:pfam10459 161 YLYKYREYKDVRLVFAPPSSIGKFGGDTDNWMWPRHTGDFSFFRAYAGKDGKPADYSKDNVPYKPKHFLKISLKGVKEGD 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  265 FVMAAGYPGSTSRYTLMAEVENTFGWTYPTFQTLLTDWIATIEEAAPQGTDARVKYESRLAGLNNFEKNLRGQIEGARRV 344
Cdd:pfam10459 241 FVFVAGYPGSTSRYLTSAEVEERRDWVNPARIDRRGERQALLEREMLKDPEIRIKYASKLAGSANYWKNLIGMLEGLRDL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  345 GLVERRREREEALAAWIAADPSRV-EYGKAIAELAELSEESAQASRTNFWYNNATRPA--LLGVAERLYRLSKERQKEDA 421
Cdd:pfam10459 321 DVLAKKQAREAALRAWLRKDPARRkKYGDALDELDALQAERRDLARRYYYFEEAFSGGseLLSAARTLVRLAKEREKPDA 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  422 QRESGYQERDMGFFRQGLQALDRRFDPAVDKAEWELFLTGYLAQPVDERVAVLDEALGITAdmtPADLPALLDRFYAETE 501
Cdd:pfam10459 401 EREPGYQERALPTLKKSLERIDADYDPEVDKAVLAAMLEEYRELLGADRLPAVDKLLGKEF---KGSPDAYADRLYAGSK 477

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  502 LDDAETRLALMEATPQQLEASDDPFIELAVALYDYGFQLETESKTRAGLALALRPAYMEAITGWQRESGVltYPDANSTL 581
Cdd:pfam10459 478 LTDPANRLALLEGGKAAVEASKDPMIALAVALADARRALEKAEKELDGAIERARPLYAKARLAMYGSTPV--YPDANSTL 555

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  582 RVTYGEVLGGSPRDGMAYYPFTTLEGITEK-DTGEDPFNAPQDLLDTIEARDYGPYKLEsIGSVPVNFLSDLDSTGGNSG 660
Cdd:pfam10459 556 RLTYGQVKGYSPRDGVYYPPFTTLDGVFEKeDTGEEPFDVPEKLLDAIEAKDFGRYAAE-NGSVPVNFLSTNDITGGNSG 634

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 736904620  661 SATLNARAELVGLLFDGTFESVNSDWDFDPRTTRTIHVDTRYMLWVMDKVDGAERLIEEMD 721
Cdd:pfam10459 635 SPVLNGKGELVGLAFDGNWESLSGDIGFDPDLQRAVAVDIRYILWALDKVYGADHLIDELT 695
 
Name Accession Description Interval E-value
Peptidase_S46 pfam10459
Peptidase S46; Dipeptidyl-peptidase 7 (DPP-7) is the best characterized member of this family. ...
 27-721 0e+00

Peptidase S46; Dipeptidyl-peptidase 7 (DPP-7) is the best characterized member of this family. It is a serine peptidase that is located on the cell surface and is predicted to have two N-terminal transmembrane domains.


Pssm-ID: 431297  Cd Length: 695  Bit Score: 890.07  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620   27 EGMFTPDQLQEIAGQLEEAGLEIEAEELADLTGFPMGAIVS-LGGCSASFVSPTGLVVTNHHCARGSVQYNSTADNNYLE 105
Cdd:pfam10459   2 EGMWTPQQLPEQADKLKALGLEIDAEWLYNLRRSSKDAVVRfGGGCTGSFVSPDGLVLTNHHCAYGAIQQHSSVEHDYLK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  106 NGFLANALAEELPAaPGSRIYVTTQVTDVTDRMRAGTE-GMEPYERYELVQQRSKDITAECEEDAGFRCQVASFYGGAEY 184
Cdd:pfam10459  82 DGFLAKSRAEELPA-PGLRVTVLVRITDVTDRVRAALKaGTDGEERSKAIEARLKALAKECEKEDGLRCEVVAFYGGNEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  185 KLIKRLEVRDVRLVYAPADSIGKYGGDIDNWMWPRHTGDFAFYRAYVAPDGSAADYAEENVPYEPEHHLKVSAAGLEEGD 264
Cdd:pfam10459 161 YLYKYREYKDVRLVFAPPSSIGKFGGDTDNWMWPRHTGDFSFFRAYAGKDGKPADYSKDNVPYKPKHFLKISLKGVKEGD 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  265 FVMAAGYPGSTSRYTLMAEVENTFGWTYPTFQTLLTDWIATIEEAAPQGTDARVKYESRLAGLNNFEKNLRGQIEGARRV 344
Cdd:pfam10459 241 FVFVAGYPGSTSRYLTSAEVEERRDWVNPARIDRRGERQALLEREMLKDPEIRIKYASKLAGSANYWKNLIGMLEGLRDL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  345 GLVERRREREEALAAWIAADPSRV-EYGKAIAELAELSEESAQASRTNFWYNNATRPA--LLGVAERLYRLSKERQKEDA 421
Cdd:pfam10459 321 DVLAKKQAREAALRAWLRKDPARRkKYGDALDELDALQAERRDLARRYYYFEEAFSGGseLLSAARTLVRLAKEREKPDA 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  422 QRESGYQERDMGFFRQGLQALDRRFDPAVDKAEWELFLTGYLAQPVDERVAVLDEALGITAdmtPADLPALLDRFYAETE 501
Cdd:pfam10459 401 EREPGYQERALPTLKKSLERIDADYDPEVDKAVLAAMLEEYRELLGADRLPAVDKLLGKEF---KGSPDAYADRLYAGSK 477

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  502 LDDAETRLALMEATPQQLEASDDPFIELAVALYDYGFQLETESKTRAGLALALRPAYMEAITGWQRESGVltYPDANSTL 581
Cdd:pfam10459 478 LTDPANRLALLEGGKAAVEASKDPMIALAVALADARRALEKAEKELDGAIERARPLYAKARLAMYGSTPV--YPDANSTL 555

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736904620  582 RVTYGEVLGGSPRDGMAYYPFTTLEGITEK-DTGEDPFNAPQDLLDTIEARDYGPYKLEsIGSVPVNFLSDLDSTGGNSG 660
Cdd:pfam10459 556 RLTYGQVKGYSPRDGVYYPPFTTLDGVFEKeDTGEEPFDVPEKLLDAIEAKDFGRYAAE-NGSVPVNFLSTNDITGGNSG 634

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 736904620  661 SATLNARAELVGLLFDGTFESVNSDWDFDPRTTRTIHVDTRYMLWVMDKVDGAERLIEEMD 721
Cdd:pfam10459 635 SPVLNGKGELVGLAFDGNWESLSGDIGFDPDLQRAVAVDIRYILWALDKVYGADHLIDELT 695
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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