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Conserved domains on  [gi|737149574|ref|WP_035136546|]
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MULTISPECIES: amino acid ABC transporter permease [Collinsella]

Protein Classification

amino acid ABC transporter permease( domain architecture ID 11433582)

amino acid ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which binds and transports amino acids

Gene Ontology:  GO:0140359|GO:0042626|GO:0006865
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 10-227 3.91e-66

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 204.15  E-value: 3.91e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  10 RWSTTFQNMGPFWEGFGVTLQVVVAGLLLSLVLGTLLGVFSTTRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFlq 89
Cdd:COG0765    4 DFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPLL-- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  90 aitgadqPVRIAPFVLGFLGVGLYHAAYISEVIRTGIEAVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQAL 169
Cdd:COG0765   82 -------GIDLSPFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFI 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 737149574 170 NLVKNTSVLALVAGGDLMYRSDNFVSLYG-YLQGYIVCCLMYFIICFPLAMLVQWLERR 227
Cdd:COG0765  155 SLLKDTSLVSVIGVPELTRAAQQIASRTFrPFEVYLVAALIYLVLTLPLSLLARRLERR 213
 
Name Accession Description Interval E-value
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 10-227 3.91e-66

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 204.15  E-value: 3.91e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  10 RWSTTFQNMGPFWEGFGVTLQVVVAGLLLSLVLGTLLGVFSTTRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFlq 89
Cdd:COG0765    4 DFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPLL-- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  90 aitgadqPVRIAPFVLGFLGVGLYHAAYISEVIRTGIEAVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQAL 169
Cdd:COG0765   82 -------GIDLSPFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFI 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 737149574 170 NLVKNTSVLALVAGGDLMYRSDNFVSLYG-YLQGYIVCCLMYFIICFPLAMLVQWLERR 227
Cdd:COG0765  155 SLLKDTSLVSVIGVPELTRAAQQIASRTFrPFEVYLVAALIYLVLTLPLSLLARRLERR 213
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 11-227 1.10e-29

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 110.33  E-value: 1.10e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574   11 WSTTFQNMGPFWEGFGVTLQVVVAGLLLSLVLGTLLGVFSTTRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFlqa 90
Cdd:TIGR03003   3 WEFVRQILPTLIEGLKITILATALGFAIAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYYVLPDI--- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574   91 itgadqPVRIAPFVLGFLGVGLYHAAYISEVIRTGIEAVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALN 170
Cdd:TIGR03003  80 ------GIRLPALVAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLVA 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 737149574  171 LVKNTSVLALVAGGDLMYRSDNFVS-LYGYLQGYIVCCLMYFIICFPLAMLVQWLERR 227
Cdd:TIGR03003 154 MFKETPVLSAITVLELMNQAKSIGNsTFRYLEPMTLVGVFFLILSIISVFFLRRLEAR 211
PRK15100 PRK15100
cystine ABC transporter permease;
52-233 4.44e-26

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 101.36  E-value: 4.44e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  52 TRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFlqaitgadqPVRIAPFVLGFLGVGLYHAAYISEVIRTGIEAVPR 131
Cdd:PRK15100  46 SPIWPVRWLARFYVSIFRGTPLIAQLFMIYYGLPQF---------GIELDPIPAAMIGLSLNTAAYAAETLRAAISSIDK 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574 132 GQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALNLVKNTSVLALVAGGDLmYRSDNFVS--LYGYLQGYIVCCLM 209
Cdd:PRK15100 117 GQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKDTSLAATIQVPEL-FRQAQLITsrTLEVFTMYLAASLI 195

                        170       180
                 ....*....|....*....|....
gi 737149574 210 YFIICFPLAMLVQWLERRSKERPR 233
Cdd:PRK15100 196 YWIMATVLSALQNRFENQLNRQER 219
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 48-215 5.52e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 68.07  E-value: 5.52e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  48 VFSTTRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFLqaitgaDQPVRIAPFVLGFLGVGLYHAAYISEVIRTGIE 127
Cdd:cd06261   24 IILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLL------GWGILPGLGLPALILALLLIAPFARLIRRAALE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574 128 AVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALNLVKNTSVLALVAGGDLMY-RSDNFVSLYGYLQGYIVC 206
Cdd:cd06261   98 SIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGpGTGLLLIFAILFPGDLGV 177


                 ....*....
gi 737149574 207 CLMYFIICF 215
Cdd:cd06261  178 AAAVALILL 186
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 53-227 4.63e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 65.40  E-value: 4.63e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574   53 RSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGpqFLQAITGADQPVrIAPFVLGFlgvglyhAAYISEVIRTGIEAVPRG 132
Cdd:pfam00528  12 RGRRLDRLLRPLIDLLQALPSFVLAILLVVIA--ILSILGHGILPA-IILALLGW-------AGYARLIRRAALRSLPSD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  133 QMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALNLVKNTSVLALVAG----GDLMYRSDNFVSLYGYLQGYIVCCL 208
Cdd:pfam00528  82 LVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSwpglGLLLIEAILGYDYPEIQGPVLAAAL 161

                         170
                  ....*....|....*....
gi 737149574  209 MYFIICFPLAMLVQWLERR 227
Cdd:pfam00528 162 ILLLLNLLVDILQRLLDPR 180
 
Name Accession Description Interval E-value
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 10-227 3.91e-66

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 204.15  E-value: 3.91e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  10 RWSTTFQNMGPFWEGFGVTLQVVVAGLLLSLVLGTLLGVFSTTRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFlq 89
Cdd:COG0765    4 DFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPLL-- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  90 aitgadqPVRIAPFVLGFLGVGLYHAAYISEVIRTGIEAVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQAL 169
Cdd:COG0765   82 -------GIDLSPFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFI 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 737149574 170 NLVKNTSVLALVAGGDLMYRSDNFVSLYG-YLQGYIVCCLMYFIICFPLAMLVQWLERR 227
Cdd:COG0765  155 SLLKDTSLVSVIGVPELTRAAQQIASRTFrPFEVYLVAALIYLVLTLPLSLLARRLERR 213
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 10-227 8.40e-30

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 110.95  E-value: 8.40e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  10 RWSTTFQNMGPFWEGFGVTLQVVVAGLLLSLVLGTLLGVFSTTRSRVLRAISRVYVEFYQNTPLPVQVLFMYmAGPQFLQ 89
Cdd:COG4160    2 DLDLLFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIY-YGLGQFE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  90 AI--TGADQPVRiAPFVLGFLGVGLYHAAYISEVIRTGIEAVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQ 167
Cdd:COG4160   81 WVreSWLWPLLR-DPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILPSALRRALPAYSNE 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 737149574 168 ALNLVKNTSVLALVAGGDLMYRSDNFVS-LYGYLQGYIVCCLMYFIICFPLAMLVQWLERR 227
Cdd:COG4160  160 VILMLKATALASTITVMDLTGVARRIYSrTYDPFEPFLIAALIYLVITFLLTRLFRLLERR 220
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 11-227 1.10e-29

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 110.33  E-value: 1.10e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574   11 WSTTFQNMGPFWEGFGVTLQVVVAGLLLSLVLGTLLGVFSTTRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFlqa 90
Cdd:TIGR03003   3 WEFVRQILPTLIEGLKITILATALGFAIAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYYVLPDI--- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574   91 itgadqPVRIAPFVLGFLGVGLYHAAYISEVIRTGIEAVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALN 170
Cdd:TIGR03003  80 ------GIRLPALVAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLVA 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 737149574  171 LVKNTSVLALVAGGDLMYRSDNFVS-LYGYLQGYIVCCLMYFIICFPLAMLVQWLERR 227
Cdd:TIGR03003 154 MFKETPVLSAITVLELMNQAKSIGNsTFRYLEPMTLVGVFFLILSIISVFFLRRLEAR 211
PRK15100 PRK15100
cystine ABC transporter permease;
52-233 4.44e-26

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 101.36  E-value: 4.44e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  52 TRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFlqaitgadqPVRIAPFVLGFLGVGLYHAAYISEVIRTGIEAVPR 131
Cdd:PRK15100  46 SPIWPVRWLARFYVSIFRGTPLIAQLFMIYYGLPQF---------GIELDPIPAAMIGLSLNTAAYAAETLRAAISSIDK 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574 132 GQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALNLVKNTSVLALVAGGDLmYRSDNFVS--LYGYLQGYIVCCLM 209
Cdd:PRK15100 117 GQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKDTSLAATIQVPEL-FRQAQLITsrTLEVFTMYLAASLI 195

                        170       180
                 ....*....|....*....|....
gi 737149574 210 YFIICFPLAMLVQWLERRSKERPR 233
Cdd:PRK15100 196 YWIMATVLSALQNRFENQLNRQER 219
ectoine_ehuC TIGR03004
ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are ...
 18-227 4.75e-26

ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons. Permease subunits EhuC and EhuD are homologous.


Pssm-ID: 132049 [Multi-domain]  Cd Length: 214  Bit Score: 101.08  E-value: 4.75e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574   18 MGPFWEGFGVTLQVVVAGLLLSLVLGTLLGVFSTTRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFlqaitgadqP 97
Cdd:TIGR03004   4 LPLLLQGAWVTMQITLAGSVLATVLAFFAGLGRVSGGPILRTVALCYIEVFRGTSLLVQLFWFYFVLPLI---------G 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574   98 VRIAPFVLGFLGVGLYHAAYISEVIRTGIEAVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALNLVKNTSV 177
Cdd:TIGR03004  75 LSLDPVTTGVMVLGLHAGAYGAEIVRGALSSVSVQQLEACRALNFTRFQTLRRISLPQALVEMMPAFGNLAIELLKLTSL 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 737149574  178 LALVAGGDLMYRSDNFVSLYG-YLQGYIVCCLMYFIICFPLAMLVQWLERR 227
Cdd:TIGR03004 155 VSLISLADLTFAAQSIRNLTLdTLSIFAITLLCYFVMALIIMLIMRVLERV 205
BatB COG4597
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 98-183 5.43e-23

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443651 [Multi-domain]  Cd Length: 397  Bit Score: 95.98  E-value: 5.43e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  98 VRIAP-FVLGFLGVGLYHAAYISEVIRTGIEAVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALNLVKNTS 176
Cdd:COG4597  259 LTLSPeFVALLLALSLYTAAFIAEIVRAGIQAVSKGQTEAARALGLRPGQTLRLVVLPQALRVIIPPLTSQYLNLTKNSS 338


                 ....*..
gi 737149574 177 vLALVAG 183
Cdd:COG4597  339 -LAVAIG 344
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
11-228 5.40e-22

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 90.66  E-value: 5.40e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  11 WSTTFQNMGPFWEGFGVTLQVVVAGLLLSLVLGTLLGVFSTTRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFLQA 90
Cdd:PRK15107   6 WSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTILAVMRLSSFKPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  91 ITGADQPVRIApFVLGFLGVGLYHAAYISEVIRTGIEAVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALN 170
Cdd:PRK15107  86 VLGLSPKTDIR-LISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLTQGIV 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 737149574 171 LVKNTSVLALVAGGDLMYRSDNFVSLYG-YLQGYIVCCLMYFIICFPLAMLVQWLERRS 228
Cdd:PRK15107 165 LFQDTSLVYVLSLADFFRTASTIGERDGtQVEMILFAGFVYFVISLSASLLVSYLKKRT 223
PRK11123 PRK11123
arginine ABC transporter permease ArtQ;
48-236 5.06e-21

arginine ABC transporter permease ArtQ;


Pssm-ID: 182979 [Multi-domain]  Cd Length: 238  Bit Score: 88.20  E-value: 5.06e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  48 VFSTTRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFLQAITG---------------ADQPVRIAPFVLGFLGVGL 112
Cdd:PRK11123  34 VWESAKWRPVAWPGTALVTLLRGLPEILVVLFIYFGSSQLLLTLSDgftlnlgfvqipvqmDIENFEVSPFLCGVIALSL 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574 113 YHAAYISEVIRTGIEAVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALNLVKNTSVLALVAGGDLMYRSDN 192
Cdd:PRK11123 114 LYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPGLGNQWLVLLKDTALVSLISVNDLMLQTKS 193

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 737149574 193 FVS-LYGYLQGYIVCCLMYFIICFPLAMLVQWLERRSKERPRGVS 236
Cdd:PRK11123 194 IATrTQEPFTWYIIAAAIYLVITLISQYILKRIELRATRFERRPS 238
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 55-229 2.15e-20

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 86.26  E-value: 2.15e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  55 RVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFLqaitgadQPVRIAPFVLGFLGVGLYHAAYISEVIRTGIEAVPRGQM 134
Cdd:PRK09494  49 WIANHIALVFIELIRGTPIVVQVMFIYFALPMAF-------NDLRIDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFR 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574 135 EAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALNLVKNTSVLALVAGGDLMYRSDNFV-SLYGYLQGYIVCCLMYFII 213
Cdd:PRK09494 122 EAGLALGLSRRETLRYVIGPLALRRMLPPLGNQWIISIKDTSLFIVIGVAELTRQGQEIIaGNFRALEIWSAVAVIYLII 201

                        170
                 ....*....|....*.
gi 737149574 214 CFPLAMLVQWLERRSK 229
Cdd:PRK09494 202 TLVLSFILRRLERRMK 217
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 48-215 5.52e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 68.07  E-value: 5.52e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  48 VFSTTRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFLqaitgaDQPVRIAPFVLGFLGVGLYHAAYISEVIRTGIE 127
Cdd:cd06261   24 IILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLL------GWGILPGLGLPALILALLLIAPFARLIRRAALE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574 128 AVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALNLVKNTSVLALVAGGDLMY-RSDNFVSLYGYLQGYIVC 206
Cdd:cd06261   98 SIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGpGTGLLLIFAILFPGDLGV 177


                 ....*....
gi 737149574 207 CLMYFIICF 215
Cdd:cd06261  178 AAAVALILL 186
HEQRo_perm_3TM TIGR01726
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ...
 17-123 1.34e-13

amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130787 [Multi-domain]  Cd Length: 99  Bit Score: 64.86  E-value: 1.34e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574   17 NMGPFWEGFGVTLQVVVAGLLLSLVLGTLLGVFSTTRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFlqaitgadq 96
Cdd:TIGR01726   1 NLPFLLKGLLLTLLLSVLSILLGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIYFGLPLI--------- 71

                          90       100
                  ....*....|....*....|....*..
gi 737149574   97 PVRIAPFVLGFLGVGLYHAAYISEVIR 123
Cdd:TIGR01726  72 GIRLSPLTAAVIALTLFYGAYLAEIFR 98
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 53-227 4.63e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 65.40  E-value: 4.63e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574   53 RSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGpqFLQAITGADQPVrIAPFVLGFlgvglyhAAYISEVIRTGIEAVPRG 132
Cdd:pfam00528  12 RGRRLDRLLRPLIDLLQALPSFVLAILLVVIA--ILSILGHGILPA-IILALLGW-------AGYARLIRRAALRSLPSD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  133 QMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALNLVKNTSVLALVAG----GDLMYRSDNFVSLYGYLQGYIVCCL 208
Cdd:pfam00528  82 LVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSwpglGLLLIEAILGYDYPEIQGPVLAAAL 161

                         170
                  ....*....|....*....
gi 737149574  209 MYFIICFPLAMLVQWLERR 227
Cdd:pfam00528 162 ILLLLNLLVDILQRLLDPR 180
PRK15069 PRK15069
histidine ABC transporter permease HisM;
51-227 3.31e-12

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 63.92  E-value: 3.31e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  51 TTRSRVLRAISRVYVEFYQNTPLPVQVLFMYmAGPQFLQAITGadQPVRIAPFVLGF----LGVGLYHAAYISEVIRTGI 126
Cdd:PRK15069  49 VSSNKWIRFPVWLYTYVFRGTPLYVQLLVFY-TGMYSLEIVRG--TDLLDAFFRSGLnctiLAFTLNTCAYTTEIFAGAI 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574 127 EAVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALNLVKNTSVLALVAGGDLM--YRSDNfVSLYGYLQGYI 204
Cdd:PRK15069 126 RSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALPAYSNEVILMLHATTLAFTATVPDILkiARDIN-SATYQPFQAFG 204

                        170       180
                 ....*....|....*....|...
gi 737149574 205 VCCLMYFIICFPLAMLVQWLERR 227
Cdd:PRK15069 205 IAAVLYLIISFVLISLFRRAERR 227
PRK15135 PRK15135
histidine ABC transporter permease HisQ;
52-227 3.68e-11

histidine ABC transporter permease HisQ;


Pssm-ID: 185089 [Multi-domain]  Cd Length: 228  Bit Score: 60.96  E-value: 3.68e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  52 TRSRVLRAISRVYVEFYQNTPLPVQVLFMYMAGPQFLQAIT---GADQpVRIAPFVLGFLGVGLYHAAYISEVIRTGIEA 128
Cdd:PRK15135  40 SQNRLLGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNSVTealGVGQ-IDIDPMVAGIITLGFIYGAYFTETFRGAFMA 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574 129 VPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIILPPLCNQALNLVKNTSVLALVAGGDLMyRSDNFVSLYGYLQGY--IVC 206
Cdd:PRK15135 119 VPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQVILKATALVSLLGLEDVV-KATQLAGKSTWEPFYfaIVC 197

                        170       180
                 ....*....|....*....|.
gi 737149574 207 CLMYFIICFPLAMLVQWLERR 227
Cdd:PRK15135 198 GVIYLVFTTVSNGVLLWLERR 218
artM PRK11122
arginine ABC transporter permease ArtM;
51-227 2.24e-09

arginine ABC transporter permease ArtM;


Pssm-ID: 182978 [Multi-domain]  Cd Length: 222  Bit Score: 55.73  E-value: 2.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  51 TTRSRVLRAISRVYVEFYQNTPLPVQVLFMYmAGPQFLQAITGADQ--PVRIAPFVLGFLGVGLYHAAYISEVIRTGIEA 128
Cdd:PRK11122  38 TLKTPVLVWLVRGYITLFTGTPLLVQIFLIY-YGPGQFPWLQEYPWlwHLLSQPWLCAMLALALNSAAYSTQLFYGAVRA 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574 129 VPRGQMEAAQSQGFTRAQAYWyIVLPQTFKIILPPLCNQALNLVKNTSVLALVAGGDLMyrsdnfvslyGYLQG------ 202
Cdd:PRK11122 117 IPEGQWQSCAALGMSKKQTLR-ILLPYAFKRALSSYSNEVVLVFKSTSLAYTITLMDVM----------GYSQLlygrty 185

                        170       180
                 ....*....|....*....|....*....
gi 737149574 203 ----YIVCCLMYFIICFPLAMLVQWLERR 227
Cdd:PRK11122 186 dvmvFGAAGIIYLVVNGLLTLLMRLIERK 214
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 106-184 3.49e-06

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 46.61  E-value: 3.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574 106 GFLGVGLYHAAYISEVIRTGIEAVPRGQMEAAQSQGFTRAQAYWYIVLPQtfkiILPPLCNQAL-----NlVKNTSVLAL 180
Cdd:COG3639  122 GVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRLQVIRYGVLPQ----VLPQFLSYTLyrfeiN-IRAATVLGL 196


                 ....*
gi 737149574 181 V-AGG 184
Cdd:COG3639  197 VgAGG 201
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 106-231 2.61e-05

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 44.07  E-value: 2.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737149574  106 GFLGVGLYHAAYISEVIRTGIEAVPRGQMEAAQSQGFTRAQAYWYIVLPQtfkiILPPLCNQAL----NLVKNTSVLALV 181
Cdd:TIGR01097 129 GVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQ----VLPQFLSYTLyrfeINVRAAAVLGLV 204

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 737149574  182 AGGDLMYRSDNFVSLYGYLQgyiVCCLMYFIICfpLAMLVQWLERRSKER 231
Cdd:TIGR01097 205 GAGGIGLELDTAIGLFDYDE---VSAIILVILV--VVVIIDLISARLRRR 249
PstC COG0573
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 117-161 2.94e-03

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440338 [Multi-domain]  Cd Length: 303  Bit Score: 38.15  E-value: 2.94e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 737149574 117 YISEVIRTGIEAVPRGQMEAAQSQGFTRAQAYWYIVLPQTFKIIL 161
Cdd:COG0573  170 TITSLSRDALRAVPRSLREAALALGATRWETIRKVVLPAARSGII 214
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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