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Conserved domains on  [gi|737513169|ref|WP_035492331|]
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DnaA regulatory inactivator Hda [Glaesserella parasuis]

Protein Classification

DnaA regulatory inactivator Hda( domain architecture ID 11496820)

DnaA regulatory inactivator Hda mediates the interactions of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
 2-235 7.78e-90

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


:

Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 264.05  E-value: 7.78e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169    2 QLTLPIHQIDDDTFDNFYAENSLLLLGSLRQNFVDVQQPFFYIWGGKSSGKSHLLKAVSNHYLLNQQSATYIPLDKSHYF 81
Cdd:TIGR03420   1 QLPLDVGLPDDPTFDNFYAGGNAELLAALRQLAAGKGDRFLYLWGESGSGKSHLLQAACAAAEERGKSAIYLPLAELAQA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169   82 APTVLDNGDQLDVVCLDDIQAVAGDEEWELAIFDLFNQIREQQGLfnqckktlLLISADCPPHQLAIHLPDLRSRLTWGE 161
Cdd:TIGR03420  81 DPEVLEGLEQADLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGR--------LLIAGRAAPAQLPLRLPDLRTRLAWGL 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 737513169  162 VYRLADLDDEQKRIILQRNARNKGLELSDEVANFLLKRLDRDLQALMHKLMLLDHASLQAQRKLTLPFVKEILG 235
Cdd:TIGR03420 153 VFQLPPLSDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVLA 226
 
Name Accession Description Interval E-value
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
 2-235 7.78e-90

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 264.05  E-value: 7.78e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169    2 QLTLPIHQIDDDTFDNFYAENSLLLLGSLRQNFVDVQQPFFYIWGGKSSGKSHLLKAVSNHYLLNQQSATYIPLDKSHYF 81
Cdd:TIGR03420   1 QLPLDVGLPDDPTFDNFYAGGNAELLAALRQLAAGKGDRFLYLWGESGSGKSHLLQAACAAAEERGKSAIYLPLAELAQA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169   82 APTVLDNGDQLDVVCLDDIQAVAGDEEWELAIFDLFNQIREQQGLfnqckktlLLISADCPPHQLAIHLPDLRSRLTWGE 161
Cdd:TIGR03420  81 DPEVLEGLEQADLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGR--------LLIAGRAAPAQLPLRLPDLRTRLAWGL 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 737513169  162 VYRLADLDDEQKRIILQRNARNKGLELSDEVANFLLKRLDRDLQALMHKLMLLDHASLQAQRKLTLPFVKEILG 235
Cdd:TIGR03420 153 VFQLPPLSDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVLA 226
PRK08084 PRK08084
DnaA inactivator Hda;
1-236 3.49e-88

DnaA inactivator Hda;


Pssm-ID: 181224 [Multi-domain]  Cd Length: 235  Bit Score: 260.38  E-value: 3.49e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169   1 MQLTLPIHQIDDDTFDNFYAENSLLLLGSLRQNFVDVQQPFFYIWGGKSSGKSHLLKAVSNHYLLNQQSATYIPLDKSHY 80
Cdd:PRK08084   7 AQLSLPLYLPDDETFASFYPGDNDSLLAALQNALRQEHSGYIYLWSREGAGRSHLLHAACAELSQRGRAVGYVPLDKRAW 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169  81 FAPTVLDNGDQLDVVCLDDIQAVAGDEEWELAIFDLFNQIREQqglfnqcKKTLLLISADCPPHQLAIHLPDLRSRLTWG 160
Cdd:PRK08084  87 FVPEVLEGMEQLSLVCIDNIECIAGDELWEMAIFDLYNRILES-------GRTRLLITGDRPPRQLNLGLPDLASRLDWG 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 737513169 161 EVYRLADLDDEQKRIILQRNARNKGLELSDEVANFLLKRLDRDLQALMHKLMLLDHASLQAQRKLTLPFVKEILGL 236
Cdd:PRK08084 160 QIYKLQPLSDEEKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL 235
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
40-235 1.79e-46

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 156.12  E-value: 1.79e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169  40 PFFYIWGGKSSGKSHLLKAVSNHYLLNQQSAT--YIPLDKSHYFAPTVLDNGD---------QLDVVCLDDIQAVAGDEE 108
Cdd:COG0593   35 NPLFLYGGVGLGKTHLLHAIGNEALENNPGARvvYLTAEEFTNDFINAIRNNTieefkekyrSVDVLLIDDIQFLAGKEA 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169 109 WELAIFDLFNQIREQQGlfnQckktlLLISADCPPHQLAIHLPDLRSRLTWGEVYRLADLDDEQKRIILQRNARNKGLEL 188
Cdd:COG0593  115 TQEEFFHTFNALREAGK---Q-----IVLTSDRPPKELPGLEERLRSRLEWGLVVDIQPPDLETRIAILRKKAADRGLEL 186

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 737513169 189 SDEVANFLLKRLDRDLQALMHKLMLLDHASLQAQRKLTLPFVKEILG 235
Cdd:COG0593  187 PDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLK 233
Bac_DnaA pfam00308
Bacterial dnaA protein;
14-207 4.54e-20

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 85.07  E-value: 4.54e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169   14 TFDNFY--AENSLLLLGSLR--QNFVDVQQPFFyIWGGKSSGKSHLLKAVSNHYLLNQQSA--TYIPLDK-SHYFAPTVL 86
Cdd:pfam00308   6 TFENFVigPSNRFAHAAALTvaKAPGKAYNPLF-IYGGVGLGKTHLLHAIGNYALQNAPNLrvVYLTAEEfLNDFVDAIR 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169   87 DNG--------DQLDVVCLDDIQAVAGDEEWELAIFDLFNQireqqgLFNQCKKtlLLISADCPPHQLAIHLPDLRSRLT 158
Cdd:pfam00308  85 DNKtnqfkekyRNVDVLLIDDIQFLAGKEGTQEEFFHTFNA------LHESGKQ--IVFSSDRPPKELEELEDRLRSRFQ 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 737513169  159 WGEVYRLADLDDEQKRIILQRNARNKGLELSDEVANFLLKRLDRDLQAL 207
Cdd:pfam00308 157 WGLVTDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVREL 205
 
Name Accession Description Interval E-value
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
 2-235 7.78e-90

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 264.05  E-value: 7.78e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169    2 QLTLPIHQIDDDTFDNFYAENSLLLLGSLRQNFVDVQQPFFYIWGGKSSGKSHLLKAVSNHYLLNQQSATYIPLDKSHYF 81
Cdd:TIGR03420   1 QLPLDVGLPDDPTFDNFYAGGNAELLAALRQLAAGKGDRFLYLWGESGSGKSHLLQAACAAAEERGKSAIYLPLAELAQA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169   82 APTVLDNGDQLDVVCLDDIQAVAGDEEWELAIFDLFNQIREQQGLfnqckktlLLISADCPPHQLAIHLPDLRSRLTWGE 161
Cdd:TIGR03420  81 DPEVLEGLEQADLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGR--------LLIAGRAAPAQLPLRLPDLRTRLAWGL 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 737513169  162 VYRLADLDDEQKRIILQRNARNKGLELSDEVANFLLKRLDRDLQALMHKLMLLDHASLQAQRKLTLPFVKEILG 235
Cdd:TIGR03420 153 VFQLPPLSDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVLA 226
PRK08084 PRK08084
DnaA inactivator Hda;
1-236 3.49e-88

DnaA inactivator Hda;


Pssm-ID: 181224 [Multi-domain]  Cd Length: 235  Bit Score: 260.38  E-value: 3.49e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169   1 MQLTLPIHQIDDDTFDNFYAENSLLLLGSLRQNFVDVQQPFFYIWGGKSSGKSHLLKAVSNHYLLNQQSATYIPLDKSHY 80
Cdd:PRK08084   7 AQLSLPLYLPDDETFASFYPGDNDSLLAALQNALRQEHSGYIYLWSREGAGRSHLLHAACAELSQRGRAVGYVPLDKRAW 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169  81 FAPTVLDNGDQLDVVCLDDIQAVAGDEEWELAIFDLFNQIREQqglfnqcKKTLLLISADCPPHQLAIHLPDLRSRLTWG 160
Cdd:PRK08084  87 FVPEVLEGMEQLSLVCIDNIECIAGDELWEMAIFDLYNRILES-------GRTRLLITGDRPPRQLNLGLPDLASRLDWG 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 737513169 161 EVYRLADLDDEQKRIILQRNARNKGLELSDEVANFLLKRLDRDLQALMHKLMLLDHASLQAQRKLTLPFVKEILGL 236
Cdd:PRK08084 160 QIYKLQPLSDEEKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL 235
PRK08903 PRK08903
DnaA regulatory inactivator Hda; Validated
 2-234 3.55e-52

DnaA regulatory inactivator Hda; Validated


Pssm-ID: 236347 [Multi-domain]  Cd Length: 227  Bit Score: 168.62  E-value: 3.55e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169   2 QLTLPIHQIDDDTFDNFYAENSLLLLGSLRQNFVDVQQ-PFFYIWGGKSSGKSHLLKAVSNHYLLNQQSATYIPLDKshy 80
Cdd:PRK08903   4 QLTLDLGPPPPPTFDNFVAGENAELVARLRELAAGPVAdRFFYLWGEAGSGRSHLLQALVADASYGGRNARYLDAAS--- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169  81 fAPTVLDNGDQLDVVCLDDIQAVagDEEWELAIFDLFNQIREqqglfnqCKKTLLLISADCPPHQLAIHlPDLRSRLTWG 160
Cdd:PRK08903  81 -PLLAFDFDPEAELYAVDDVERL--DDAQQIALFNLFNRVRA-------HGQGALLVAGPAAPLALPLR-EDLRTRLGWG 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 737513169 161 EVYRLADLDDEQKRIILQRNARNKGLELSDEVANFLLKRLDRDLQALMHKLMLLDHASLQAQRKLTLPFVKEIL 234
Cdd:PRK08903 150 LVYELKPLSDADKIAALKAAAAERGLQLADEVPDYLLTHFRRDMPSLMALLDALDRYSLEQKRPVTLPLLREML 223
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
40-235 1.79e-46

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 156.12  E-value: 1.79e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169  40 PFFYIWGGKSSGKSHLLKAVSNHYLLNQQSAT--YIPLDKSHYFAPTVLDNGD---------QLDVVCLDDIQAVAGDEE 108
Cdd:COG0593   35 NPLFLYGGVGLGKTHLLHAIGNEALENNPGARvvYLTAEEFTNDFINAIRNNTieefkekyrSVDVLLIDDIQFLAGKEA 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169 109 WELAIFDLFNQIREQQGlfnQckktlLLISADCPPHQLAIHLPDLRSRLTWGEVYRLADLDDEQKRIILQRNARNKGLEL 188
Cdd:COG0593  115 TQEEFFHTFNALREAGK---Q-----IVLTSDRPPKELPGLEERLRSRLEWGLVVDIQPPDLETRIAILRKKAADRGLEL 186

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 737513169 189 SDEVANFLLKRLDRDLQALMHKLMLLDHASLQAQRKLTLPFVKEILG 235
Cdd:COG0593  187 PDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLK 233
Bac_DnaA pfam00308
Bacterial dnaA protein;
14-207 4.54e-20

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 85.07  E-value: 4.54e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169   14 TFDNFY--AENSLLLLGSLR--QNFVDVQQPFFyIWGGKSSGKSHLLKAVSNHYLLNQQSA--TYIPLDK-SHYFAPTVL 86
Cdd:pfam00308   6 TFENFVigPSNRFAHAAALTvaKAPGKAYNPLF-IYGGVGLGKTHLLHAIGNYALQNAPNLrvVYLTAEEfLNDFVDAIR 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169   87 DNG--------DQLDVVCLDDIQAVAGDEEWELAIFDLFNQireqqgLFNQCKKtlLLISADCPPHQLAIHLPDLRSRLT 158
Cdd:pfam00308  85 DNKtnqfkekyRNVDVLLIDDIQFLAGKEGTQEEFFHTFNA------LHESGKQ--IVFSSDRPPKELEELEDRLRSRFQ 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 737513169  159 WGEVYRLADLDDEQKRIILQRNARNKGLELSDEVANFLLKRLDRDLQAL 207
Cdd:pfam00308 157 WGLVTDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVREL 205
dnaA PRK00149
chromosomal replication initiator protein DnaA;
40-234 1.48e-18

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 83.26  E-value: 1.48e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169  40 PFFyIWGGKSSGKSHLLKAVSNHYLLNQQSAT--YIPldkSHYFAPTV---LDNGDQ---------LDVVCLDDIQAVAG 105
Cdd:PRK00149 101 PLF-IYGGVGLGKTHLLHAIGNYILEKNPNAKvvYVT---SEKFTNDFvnaLRNNTMeefkekyrsVDVLLIDDIQFLAG 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169 106 DEEWELAIFDLFNQireqqgLFNQCKKtlLLISADCPPHQLAiHLPD-LRSRLTWGEVyrlADLD--DEQKRI-ILQRNA 181
Cdd:PRK00149 177 KERTQEEFFHTFNA------LHEAGKQ--IVLTSDRPPKELP-GLEErLRSRFEWGLT---VDIEppDLETRIaILKKKA 244

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 737513169 182 RNKGLELSDEVANFLLKRLD---RDLQALMHKLMLldHASLQaQRKLTLPFVKEIL 234
Cdd:PRK00149 245 EEEGIDLPDEVLEFIAKNITsnvRELEGALNRLIA--YASLT-GKPITLELAKEAL 297
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 14-234 1.47e-17

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 80.65  E-value: 1.47e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169   14 TFDNFY--AENSLLLLGSLR--QNFVDVQQPFFyIWGGKSSGKSHLLKAVSNHYLLNQQSAT--YIpldKSHYFAPTVLD 87
Cdd:TIGR00362 109 TFDNFVvgKSNRLAHAAALAvaENPGKAYNPLF-IYGGVGLGKTHLLHAIGNEILENNPNAKvlYV---SSEKFTNDFVN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169   88 ---NGD---------QLDVVCLDDIQAVAGDEEWELAIFDLFNQireqqgLFNQCKKtlLLISADCPPHQLAiHLPD-LR 154
Cdd:TIGR00362 185 alrNNKmeefkekyrSVDLLLIDDIQFLAGKERTQEEFFHTFNA------LHENNKQ--IVLTSDRPPKELP-GLEDrLR 255

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169  155 SRLTWGEVyrlADLD--DEQKRI-ILQRNARNKGLELSDEVANFLLKRLD---RDLQALMHKLMLldHASLQaQRKLTLP 228
Cdd:TIGR00362 256 SRFEWGLV---VDIEppDLETRLaILQKKAEEEGLELPDEVLEFIAKNITsnvRELEGALNRLLA--YASLT-GKPITLE 329


                  ....*.
gi 737513169  229 FVKEIL 234
Cdd:TIGR00362 330 LAKEAL 335
PRK12422 PRK12422
chromosomal replication initiator protein DnaA;
14-214 2.77e-14

chromosomal replication initiator protein DnaA;


Pssm-ID: 183521 [Multi-domain]  Cd Length: 445  Bit Score: 71.41  E-value: 2.77e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169  14 TFDNFYAENSLLLLGSLRQNFVDV-----QQPF--FYIWGGKSSGKSHLLKAVSNHYLLNQQSATYIPLDKSHYFAPTVL 86
Cdd:PRK12422 109 TFANFLVTPENDLPHRILQEFTKVseqgkGFPFnpIYLFGPEGSGKTHLMQAAVHALRESGGKILYVRSELFTEHLVSAI 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169  87 DNGD---------QLDVVCLDDIQAVAGDEEWELAIFDLFNQIreqqglfnQCKKTLLLISADCPPHQLAIHLPDLRSRL 157
Cdd:PRK12422 189 RSGEmqrfrqfyrNVDALFIEDIEVFSGKGATQEEFFHTFNSL--------HTEGKLIVISSTCAPQDLKAMEERLISRF 260

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 737513169 158 TWGEVYRLADLDDEQKRIILQRNARNKGLELSDEVANFLLKRLDRDLQALMHKLMLL 214
Cdd:PRK12422 261 EWGIAIPLHPLTKEGLRSFLERKAEALSIRIEETALDFLIEALSSNVKSLLHALTLL 317
PRK06620 PRK06620
hypothetical protein; Validated
 44-234 4.39e-14

hypothetical protein; Validated


Pssm-ID: 168630  Cd Length: 214  Bit Score: 68.72  E-value: 4.39e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169  44 IWGGKSSGKSHLLKA---VSNHYLLnqqsatyipldKSHYFAPTVLDNGDQLdvvCLDDIqavagdEEW-ELAIFDLFNQ 119
Cdd:PRK06620  49 IKGPSSSGKTYLTKIwqnLSNAYII-----------KDIFFNEEILEKYNAF---IIEDI------ENWqEPALLHIFNI 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169 120 IREQQglfnqckKTLLLISADcppHQLAIHLPDLRSRLTWGEVYRLADLDDEQKRIILQRNARNKGLELSDEVANFLLKR 199
Cdd:PRK06620 109 INEKQ-------KYLLLTSSD---KSRNFTLPDLSSRIKSVLSILLNSPDDELIKILIFKHFSISSVTISRQIIDFLLVN 178

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 737513169 200 LDRDLQALMHKLMLLDHASLQAQRKLTLPFVKEIL 234
Cdd:PRK06620 179 LPREYSKIIEILENINYFALISKRKITISLVKEVL 213
dnaA PRK14086
chromosomal replication initiator protein DnaA;
40-222 7.42e-14

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 70.24  E-value: 7.42e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169  40 PFFyIWGGKSSGKSHLLKAVSnHYLLNQQSATYIPLDKSHYFAPTVL-----DNGD-------QLDVVCLDDIQAVAGDE 107
Cdd:PRK14086 316 PLF-IYGESGLGKTHLLHAIG-HYARRLYPGTRVRYVSSEEFTNEFInsirdGKGDsfrrryrEMDILLVDDIQFLEDKE 393

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169 108 EWELAIFDLFNQireqqgLFNQCKKtlLLISADCPPHQLAIHLPDLRSRLTWGEVYRLADLDDEQKRIILQRNARNKGLE 187
Cdd:PRK14086 394 STQEEFFHTFNT------LHNANKQ--IVLSSDRPPKQLVTLEDRLRNRFEWGLITDVQPPELETRIAILRKKAVQEQLN 465

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 737513169 188 LSDEVANFLLKRLDRDLQALMHKLM-LLDHASLQAQ 222
Cdd:PRK14086 466 APPEVLEFIASRISRNIRELEGALIrVTAFASLNRQ 501
PRK09087 PRK09087
hypothetical protein; Validated
 24-234 7.58e-10

hypothetical protein; Validated


Pssm-ID: 169652 [Multi-domain]  Cd Length: 226  Bit Score: 56.99  E-value: 7.58e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169  24 LLLLGSLRQNFVDVQQ------PFFYIWGGKSSGKSHLLK-------AVSNHYLLNQQSATYIPLDKShyfaptvldngd 90
Cdd:PRK09087  23 LLVTESNRAAVSLVDHwpnwpsPVVVLAGPVGSGKTHLASiwreksdALLIHPNEIGSDAANAAAEGP------------ 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169  91 qldvVCLDDIQAVAGDEEwelAIFDLFNQIREQQglfnqckkTLLLISADCPPHQLAIHLPDLRSRLTWGEVYRLADLDD 170
Cdd:PRK09087  91 ----VLIEDIDAGGFDET---GLFHLINSVRQAG--------TSLLMTSRLWPSSWNVKLPDLKSRLKAATVVEIGEPDD 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 737513169 171 EQKRIILQRNARNKGLELSDEVANFLLKRLDRDLQALMHKLMLLDHASLQAQRKLTLPFVKEIL 234
Cdd:PRK09087 156 ALLSQVIFKLFADRQLYVDPHVVYYLVSRMERSLFAAQTIVDRLDRLALERKSRITRALAAEVL 219
HolA COG1466
DNA polymerase III, delta subunit [Replication, recombination and repair];
132-235 2.16e-04

DNA polymerase III, delta subunit [Replication, recombination and repair];


Pssm-ID: 441075 [Multi-domain]  Cd Length: 305  Bit Score: 41.39  E-value: 2.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737513169 132 KTLLLISADCPPH-QLAIHLPDLRSRLTW-------GEVYRLADLDDEQKRIILQRNARNKGLELSDEVANFLLKRLDRD 203
Cdd:COG1466   82 EALEAYLANPPPDtVLVLTAGKLDKRKKLfkalekaGVVVECYPLKERELPAWIRQRLKAAGLRIDPDAAQLLAERVGGD 161

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 737513169 204 LQAL---MHKLMLLdhasLQAQRKLTLPFVKEILG 235
Cdd:COG1466  162 LLALaqeLEKLALY----AGDGGTITLEDVEALVG 192
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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