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Conserved domains on  [gi|737514940|ref|WP_035493998|]
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ABC transporter substrate-binding protein [Glaesserella parasuis]

Protein Classification

ABC transporter substrate-binding protein( domain architecture ID 10006830)

ABC transporter substrate-binding protein is the type I periplasmic binding protein that functions as the primary receptor of an uncharacterized ABC-type transport system, which is predicted to be involved in the uptake of a variety of substrates such as amino acids, peptides, or inorganic ions

Gene Ontology:  GO:0140359|GO:0042626|GO:0055052
PubMed:  8336670|17578454|26517916|24638992|25750732
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG2984 COG2984
ABC-type uncharacterized transport system, periplasmic component [General function prediction ...
 24-309 8.33e-111

ABC-type uncharacterized transport system, periplasmic component [General function prediction only];


:

Pssm-ID: 442223  Cd Length: 284  Bit Score: 323.01  E-value: 8.33e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940  24 KIHNVAITAIVEHPALDTIRQGVIEELAREGFvdGKNISINFQSAQGSTSTAAQIARKFVGDKTDIIIPISTPSAQPVVA 103
Cdd:COG2984    1 KPKKIGILQISEHPALDAAREGFKDGLAEAGY--GKNLKLDYQNAQGDQATAAQIAAKLVADKPDLIVAIGTPAAQAAAN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 104 ATRSIPIVFSGVTDPVAAKLIKSWEPSKTNVTGISDHKPIEPQLALIQKLVPNIKALGYVYSAGEVNSAVVLEELRNAIR 183
Cdd:COG2984   79 ATKDIPVVFTAVTDPVGAGLVKSLEKPGGNVTGVSDLLPIEKQLELIKKLLPDAKRIGVLYNPSEANSVAQVEELKKAAK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 184 GSNIEIMPVAVQRSADIGTAARSLSGKVQAIYITEDNAVVSAYEALHKAALEAKIPVIAADKDTVKRGALAAYAVNQYDI 263
Cdd:COG2984  159 KLGLELVEATVTSSNEIQQALQSLAGKVDAIYVPTDNTVVSALEAIAKVAARAKIPVFGGDDSSVKAGALAGYGIDYYEL 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 737514940 264 GAETGKVAAKILRGEKAGNIATQSVSKMELSINQKTARQLGLSIPE 309
Cdd:COG2984  239 GRQAAEMALRILKGEKPADIPVETPKKFELVINLKTAKALGITLPE 284
 
Name Accession Description Interval E-value
COG2984 COG2984
ABC-type uncharacterized transport system, periplasmic component [General function prediction ...
 24-309 8.33e-111

ABC-type uncharacterized transport system, periplasmic component [General function prediction only];


Pssm-ID: 442223  Cd Length: 284  Bit Score: 323.01  E-value: 8.33e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940  24 KIHNVAITAIVEHPALDTIRQGVIEELAREGFvdGKNISINFQSAQGSTSTAAQIARKFVGDKTDIIIPISTPSAQPVVA 103
Cdd:COG2984    1 KPKKIGILQISEHPALDAAREGFKDGLAEAGY--GKNLKLDYQNAQGDQATAAQIAAKLVADKPDLIVAIGTPAAQAAAN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 104 ATRSIPIVFSGVTDPVAAKLIKSWEPSKTNVTGISDHKPIEPQLALIQKLVPNIKALGYVYSAGEVNSAVVLEELRNAIR 183
Cdd:COG2984   79 ATKDIPVVFTAVTDPVGAGLVKSLEKPGGNVTGVSDLLPIEKQLELIKKLLPDAKRIGVLYNPSEANSVAQVEELKKAAK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 184 GSNIEIMPVAVQRSADIGTAARSLSGKVQAIYITEDNAVVSAYEALHKAALEAKIPVIAADKDTVKRGALAAYAVNQYDI 263
Cdd:COG2984  159 KLGLELVEATVTSSNEIQQALQSLAGKVDAIYVPTDNTVVSALEAIAKVAARAKIPVFGGDDSSVKAGALAGYGIDYYEL 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 737514940 264 GAETGKVAAKILRGEKAGNIATQSVSKMELSINQKTARQLGLSIPE 309
Cdd:COG2984  239 GRQAAEMALRILKGEKPADIPVETPKKFELVINLKTAKALGITLPE 284
PBP1_ABC_unchar_transporter cd06325
type 1 periplasmic ligand-binding domain of uncharacterized ABC-type transport systems ...
 28-307 1.89e-106

type 1 periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally.


Pssm-ID: 380548  Cd Length: 282  Bit Score: 311.75  E-value: 1.89e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940  28 VAITAIVEHPALDTIRQGVIEELAREGFVDGKNISINFQSAQGSTSTAAQIARKFVGDKTDIIIPISTPSAQPVVAATRS 107
Cdd:cd06325    2 IGILQFGSHPALDAAREGFRDGLRELGYVEGKNVEIEYRNAQGDPERLPQIAAELVALKPDVIVAIGTPAAQAAKAATKT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 108 IPIVFSGVTDPVAAKLIKSWEPSKTNVTGISDHKPIEPQLALIQKLVPNIKALGYVYSAGEVNSAVVLEELRNAIRGSNI 187
Cdd:cd06325   82 IPIVFAAVTDPVGAGLVASLARPGGNVTGVSDLEPVGKRLELLKELLPNAKRVGVLYNPGEPNSVAQLEELEAAAKKLGL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 188 EIMPVAVQRSADIGTAARSLSGKV-QAIYITEDNAVVSAYEALHKAALEAKIPVIAADKDTVKRGALAAYAVNQYDIGAE 266
Cdd:cd06325  162 ELVEVPVSSPADIEQAFASLAGKVaDALYVPTDNTVASARPRIAALALKARIPVIYSDREFVEAGALMSYGPDYYDLGRQ 241

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 737514940 267 TGKVAAKILRGEKAGNIATQSVSKMELSINQKTARQLGLSI 307
Cdd:cd06325  242 AARYVDRILKGAKPADLPVEQPTKFELVINLKTAKALGLTI 282
ABC_sub_bind pfam04392
ABC transporter substrate binding protein; This family contains many hypothetical proteins and ...
 28-317 3.58e-94

ABC transporter substrate binding protein; This family contains many hypothetical proteins and some ABC transporter substrate binding proteins.


Pssm-ID: 427918  Cd Length: 293  Bit Score: 281.30  E-value: 3.58e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940   28 VAITAIVEHPALDTIRQGVIEELAREGFVDGKNISINFQSAQGSTSTAAQIARKFVGDKTDIIIPISTPSAQPVVAATRS 107
Cdd:pfam04392   2 VAVAVFVEHPSLDAIVGGIQEGLKDLGYEDGKNLLYDYKNAQGDPEILAQIANQLKGKRPDLIVGIATPEAQALVSATKN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940  108 IPIVFSGVTDPVAAKLIKSWEPSKTNVTGISDHKPIEPQLALIQKLVPNIKALGYVYSAGEVNSAVVLEELRNAIRGSNI 187
Cdd:pfam04392  82 IPIVFAAVTDPVGAGLTKSLERPGENVTGVSDAEPMEKQIELIKYMLPNVKKIGIVYSPSEANSVKAVEELKLYAKKFGL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940  188 EIMPVAVQRSADIGTAARSLSGKVQAIYITEDNAVVSAYEALHKAALEAKIPVIAADKDTVKRGALAAYAVNQYDIGAET 267
Cdd:pfam04392 162 KLVTAYVPDSNDVESAVSHMKEKVDAIYILTDNTIVSGFETLVHYANFAKIPVFASDTESVKRGAIAAVGIDYKEIGVQT 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 737514940  268 GKVAAKILRGEKAGNIATQSVSKMELSINQKTARQLGLSIPESLLQEAKE 317
Cdd:pfam04392 242 GHMAVKILKGIKPGDIPFVVAKSPKLFINLKAAQELGITIPERLLVYADE 291
 
Name Accession Description Interval E-value
COG2984 COG2984
ABC-type uncharacterized transport system, periplasmic component [General function prediction ...
 24-309 8.33e-111

ABC-type uncharacterized transport system, periplasmic component [General function prediction only];


Pssm-ID: 442223  Cd Length: 284  Bit Score: 323.01  E-value: 8.33e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940  24 KIHNVAITAIVEHPALDTIRQGVIEELAREGFvdGKNISINFQSAQGSTSTAAQIARKFVGDKTDIIIPISTPSAQPVVA 103
Cdd:COG2984    1 KPKKIGILQISEHPALDAAREGFKDGLAEAGY--GKNLKLDYQNAQGDQATAAQIAAKLVADKPDLIVAIGTPAAQAAAN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 104 ATRSIPIVFSGVTDPVAAKLIKSWEPSKTNVTGISDHKPIEPQLALIQKLVPNIKALGYVYSAGEVNSAVVLEELRNAIR 183
Cdd:COG2984   79 ATKDIPVVFTAVTDPVGAGLVKSLEKPGGNVTGVSDLLPIEKQLELIKKLLPDAKRIGVLYNPSEANSVAQVEELKKAAK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 184 GSNIEIMPVAVQRSADIGTAARSLSGKVQAIYITEDNAVVSAYEALHKAALEAKIPVIAADKDTVKRGALAAYAVNQYDI 263
Cdd:COG2984  159 KLGLELVEATVTSSNEIQQALQSLAGKVDAIYVPTDNTVVSALEAIAKVAARAKIPVFGGDDSSVKAGALAGYGIDYYEL 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 737514940 264 GAETGKVAAKILRGEKAGNIATQSVSKMELSINQKTARQLGLSIPE 309
Cdd:COG2984  239 GRQAAEMALRILKGEKPADIPVETPKKFELVINLKTAKALGITLPE 284
PBP1_ABC_unchar_transporter cd06325
type 1 periplasmic ligand-binding domain of uncharacterized ABC-type transport systems ...
 28-307 1.89e-106

type 1 periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally.


Pssm-ID: 380548  Cd Length: 282  Bit Score: 311.75  E-value: 1.89e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940  28 VAITAIVEHPALDTIRQGVIEELAREGFVDGKNISINFQSAQGSTSTAAQIARKFVGDKTDIIIPISTPSAQPVVAATRS 107
Cdd:cd06325    2 IGILQFGSHPALDAAREGFRDGLRELGYVEGKNVEIEYRNAQGDPERLPQIAAELVALKPDVIVAIGTPAAQAAKAATKT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 108 IPIVFSGVTDPVAAKLIKSWEPSKTNVTGISDHKPIEPQLALIQKLVPNIKALGYVYSAGEVNSAVVLEELRNAIRGSNI 187
Cdd:cd06325   82 IPIVFAAVTDPVGAGLVASLARPGGNVTGVSDLEPVGKRLELLKELLPNAKRVGVLYNPGEPNSVAQLEELEAAAKKLGL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 188 EIMPVAVQRSADIGTAARSLSGKV-QAIYITEDNAVVSAYEALHKAALEAKIPVIAADKDTVKRGALAAYAVNQYDIGAE 266
Cdd:cd06325  162 ELVEVPVSSPADIEQAFASLAGKVaDALYVPTDNTVASARPRIAALALKARIPVIYSDREFVEAGALMSYGPDYYDLGRQ 241

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 737514940 267 TGKVAAKILRGEKAGNIATQSVSKMELSINQKTARQLGLSI 307
Cdd:cd06325  242 AARYVDRILKGAKPADLPVEQPTKFELVINLKTAKALGLTI 282
ABC_sub_bind pfam04392
ABC transporter substrate binding protein; This family contains many hypothetical proteins and ...
 28-317 3.58e-94

ABC transporter substrate binding protein; This family contains many hypothetical proteins and some ABC transporter substrate binding proteins.


Pssm-ID: 427918  Cd Length: 293  Bit Score: 281.30  E-value: 3.58e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940   28 VAITAIVEHPALDTIRQGVIEELAREGFVDGKNISINFQSAQGSTSTAAQIARKFVGDKTDIIIPISTPSAQPVVAATRS 107
Cdd:pfam04392   2 VAVAVFVEHPSLDAIVGGIQEGLKDLGYEDGKNLLYDYKNAQGDPEILAQIANQLKGKRPDLIVGIATPEAQALVSATKN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940  108 IPIVFSGVTDPVAAKLIKSWEPSKTNVTGISDHKPIEPQLALIQKLVPNIKALGYVYSAGEVNSAVVLEELRNAIRGSNI 187
Cdd:pfam04392  82 IPIVFAAVTDPVGAGLTKSLERPGENVTGVSDAEPMEKQIELIKYMLPNVKKIGIVYSPSEANSVKAVEELKLYAKKFGL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940  188 EIMPVAVQRSADIGTAARSLSGKVQAIYITEDNAVVSAYEALHKAALEAKIPVIAADKDTVKRGALAAYAVNQYDIGAET 267
Cdd:pfam04392 162 KLVTAYVPDSNDVESAVSHMKEKVDAIYILTDNTIVSGFETLVHYANFAKIPVFASDTESVKRGAIAAVGIDYKEIGVQT 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 737514940  268 GKVAAKILRGEKAGNIATQSVSKMELSINQKTARQLGLSIPESLLQEAKE 317
Cdd:pfam04392 242 GHMAVKILKGIKPGDIPFVVAKSPKLFINLKAAQELGITIPERLLVYADE 291
RbsB COG1879
ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH ...
 4-279 1.80e-06

ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain [Carbohydrate transport and metabolism];


Pssm-ID: 441483 [Multi-domain]  Cd Length: 307  Bit Score: 48.77  E-value: 1.80e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940   4 RKTILFSALAAFAF------------NASAQDKIHNVAITAIVEHPALDTIRQGVIEELAREGfvdgknISINFQSAQGS 71
Cdd:COG1879    1 KRLALLAAVLALALalaacgsaaaeaAAAAAKGKTIGFVVKTLGNPFFVAVRKGAEAAAKELG------VELIVVDAEGD 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940  72 TSTAAQIARKFVGDKTDIII--PISTPSAQPVV--AATRSIPIVF--SGVTDPVAAklikswepskTNVTgiSDHKPIEP 145
Cdd:COG1879   75 AAKQISQIEDLIAQGVDAIIvsPVDPDALAPALkkAKAAGIPVVTvdSDVDGSDRV----------AYVG--SDNYAAGR 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 146 QLA--LIQKLVPNIKALGYVYSAGEVNSAVVLEELRNAIRG-SNIEImpVAVQRSADIGTAARSL-------SGKVQAIY 215
Cdd:COG1879  143 LAAeyLAKALGGKGKVAILTGSPGAPAANERTDGFKEALKEyPGIKV--VAEQYADWDREKALEVmedllqaHPDIDGIF 220

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 216 ITEDNAVVSAYEALHKAALEAKIPVIAAD--KDT---VKRGALAA-YAVNQYDIGAETGKVAAKILRGEK 279
Cdd:COG1879  221 AANDGMALGAAQALKAAGRKGDVKVVGFDgsPEAlqaIKDGTIDAtVAQDPYLQGYLAVDAALKLLKGKE 290
PBP1_sensor_kinase-like cd06308
periplasmic binding domain of two-component sensor kinase signaling systems; Periplasmic ...
 36-279 1.16e-04

periplasmic binding domain of two-component sensor kinase signaling systems; Periplasmic binding domain of two-component sensor kinase signaling systems, some of which are fused with a C-terminal histidine kinase A domain (HisK) and/or a signal receiver domain (REC). Members of this group share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily and are predicted to be involved in sensing of environmental stimuli; their substrate specificities, however, are not known in detail.


Pssm-ID: 380531 [Multi-domain]  Cd Length: 268  Bit Score: 42.92  E-value: 1.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940  36 HPALDTIRQGVIEELAREgfvdgKNISINFQSAQGSTSTAAQIARKFVGDKTDIII--PISTPSAQPVV--AATRSIPIV 111
Cdd:cd06308   11 DPWRAAMNEEIKAEAAKY-----PNVELIVTDAQGDAAKQIADIEDLIAQGVDLLIvsPNEADALTPVVkkAYDAGIPVI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 112 F--SGV-TDPV--------------AAKLIKSWEPSKTNV---TGISDHKP-IEPQLALIQKLV--PNIKALGYVYSage 168
Cdd:cd06308   86 VldRKVsGDDYtafigadnveigrqAGEYIAELLNGKGNVveiQGLPGSSPaIDRHKGFLEAIAkyPGIKIVASQDG--- 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 169 vnsavvleelrNAIRGSNIEIMPVAVQRSADIgtaarslsgkvQAIYITEDNAVVSAYEALHKAALEAKIPVIAAD---- 244
Cdd:cd06308  163 -----------DWLRDKAIKVMEDLLQAHPDI-----------DAVYAHNDEMALGAYQALKKAGREKEIKIIGVDglpe 220

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 737514940 245 --KDTVKRGALAAYAVNqYDIGAETGKVAAKILRGEK 279
Cdd:cd06308  221 agEKAVKDGILAATFLY-PTGGKEAIEAALKILNGEK 256
PBP1_ABC_sugar_binding-like cd20005
monosaccharide ABC transporter substrate-binding protein such as CUT2; Periplasmic ...
 186-279 2.32e-04

monosaccharide ABC transporter substrate-binding protein such as CUT2; Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.


Pssm-ID: 380660 [Multi-domain]  Cd Length: 274  Bit Score: 42.23  E-value: 2.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 186 NIEIMPVAVQRSADIGTAARSLSGKVQAIYITEDNAVVSAYEALHKAALEAKIPVIAAD-----KDTVKRGALAAYAV-N 259
Cdd:cd20005  160 NVQYGVGDHAKAADIAKAILQANPDLKGIYATNEGAAIGVANALKEMGKLGKIKVVGFDsgeaqIDAIKNGVIAGSVTqN 239

                         90       100
                 ....*....|....*....|
gi 737514940 260 QYDIGAETGKVAAKILRGEK 279
Cdd:cd20005  240 PYGMGYKTVKAAVKALKGEE 259
RbsB COG1879
ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH ...
 207-284 4.14e-03

ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain [Carbohydrate transport and metabolism];


Pssm-ID: 441483 [Multi-domain]  Cd Length: 307  Bit Score: 38.37  E-value: 4.14e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 737514940 207 LSGKVQAIYITedNAVVSAYEALHKAALEAKIPVIAADKDTVKRGALAAYAVNQYDIGAETGKVAAKILRGEkaGNIA 284
Cdd:COG1879   86 IAQGVDAIIVS--PVDPDALAPALKKAKAAGIPVVTVDSDVDGSDRVAYVGSDNYAAGRLAAEYLAKALGGK--GKVA 159
LivK COG0683
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid ...
 32-118 6.20e-03

ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid transport and metabolism];


Pssm-ID: 440447 [Multi-domain]  Cd Length: 314  Bit Score: 37.99  E-value: 6.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940  32 AIVEHPALDTIRQGViEELAREGFVDGKNISINFQSAQGSTSTAAQIARKFVG-DKTDIII-PISTPSAQPV--VAATRS 107
Cdd:COG0683   17 AALGQPIKNGAELAV-EEINAAGGVLGRKIELVVEDDASDPDTAVAAARKLIDqDKVDAIVgPLSSGVALAVapVAEEAG 95

                         90
                 ....*....|.
gi 737514940 108 IPIVFSGVTDP 118
Cdd:COG0683   96 VPLISPSATAP 106
PBP1_ABC_sugar_binding-like cd01536
periplasmic sugar-binding domain of active transport systems that are members of the type 1 ...
 231-284 6.66e-03

periplasmic sugar-binding domain of active transport systems that are members of the type 1 periplasmic binding protein (PBP1) superfamily; Periplasmic sugar-binding domain of active transport systems that are members of the type 1 periplasmic binding protein (PBP1) superfamily. The members of this family function as the primary receptors for chemotaxis and transport of many sugar based solutes in bacteria and archaea. The sugar binding domain is also homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR. Moreover, this periplasmic binding domain, also known as Venus flytrap domain, undergoes transition from an open to a closed conformational state upon the binding of ligands such as lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars. This family also includes the periplasmic binding domain of autoinducer-2 (AI-2) receptors such as LsrB and LuxP which are highly homologous to periplasmic pentose/hexose sugar-binding proteins.


Pssm-ID: 380478 [Multi-domain]  Cd Length: 268  Bit Score: 37.55  E-value: 6.66e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 737514940 231 KAALEAKIPVIAADKDTVKRGALAAY-AVNQYDIGAETGKVAAKILRGEkaGNIA 284
Cdd:cd01536   74 KKANAAGIPVVAVDTDIDGGGDVVAFvGTDNYEAGKLAGEYLAEALGGK--GKVA 126
PBP1_allose_binding cd06320
periplasmic allose-binding domain of bacterial transport systems that function as a primary ...
 41-279 9.77e-03

periplasmic allose-binding domain of bacterial transport systems that function as a primary receptor of active transport and chemotaxis; Periplasmic allose-binding domain of bacterial transport systems that function as a primary receptor of active transport and chemotaxis. The members of this group are belonging to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily. Like other periplasmic receptors of the ABC-type transport systems, the allose-binding protein consists of two alpha/beta domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding.


Pssm-ID: 380543 [Multi-domain]  Cd Length: 283  Bit Score: 37.24  E-value: 9.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940  41 TIRQGVIEELAREGfvdgknISINFQSAQGSTSTAAQ--IARKFVGDKTDIII--PISTPSAQPVV--AATRSIPIVfsG 114
Cdd:cd06320   16 AMKDGIEAEAKKLG------VKVDVQAAPSETDTQGQlnLLETMLNKGYDAILvsPISDTNLIPPIekANKKGIPVI--N 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 115 VTDPVAAKLIKSWEPSKTNVTGiSDHKPIEPQLAliQKLVPNIKALGYVY----SAGEVNSAVVLEELRNAIRG-SNIEI 189
Cdd:cd06320   88 LDDAVDADALKKAGGKVTSFIG-TDNVAAGALAA--EYIAEKLPGGGKVAiiegLPGNAAAEARTKGFKETFKKaPGLKL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737514940 190 mpVAVQ-------RSADIGTAARSLSGKVQAIYITEDNAVVSAYEALHKAALEAKIPVIAAD-----KDTVKRGALAA-Y 256
Cdd:cd06320  165 --VASQpadwdrtKALDAATAILQAHPDLKGIYAANDTMALGAVEAVKAAGKTGKVLVVGTDgipeaKKSIKAGELTAtV 242

                        250       260
                 ....*....|....*....|...
gi 737514940 257 AVNQYDIGAETGKVAAKILRGEK 279
Cdd:cd06320  243 AQYPYLEGAMAVEAALRLLQGQK 265
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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