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Conserved domains on  [gi|737546409|ref|WP_035519547|]
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iron ABC transporter permease [Glaesserella parasuis]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 24-325 5.01e-110

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 322.02  E-value: 5.01e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  24 VGAFSLTWQDLVAA----DLNSNVWQIWLNIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALS 99
Cdd:COG0609    4 LGAVPISLSDVLRAllgpDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGAVLA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 100 ILLPNILptewGIYSTMLFAFMGSLAVTGFIYALSHR-TQASMQKLLLAGIAVNALCFAIVGMLTYISNDQQLRQFTLWT 178
Cdd:COG0609   84 IVLGGGL----SALGLPLAAFLGALLAALLVYLLARRgGGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRSIVFWL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 179 MGSLGQAQWQPLFIASTLILPACLYLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGL 258
Cdd:COG0609  160 MGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGL 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 737546409 259 VIPHLVRFKLGADHRWVLPASALCGAILLLIADTFARTAFAPAELPVGMITSFLGAPYFLWLVVRYR 325
Cdd:COG0609  240 VVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 24-325 5.01e-110

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 322.02  E-value: 5.01e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  24 VGAFSLTWQDLVAA----DLNSNVWQIWLNIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALS 99
Cdd:COG0609    4 LGAVPISLSDVLRAllgpDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGAVLA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 100 ILLPNILptewGIYSTMLFAFMGSLAVTGFIYALSHR-TQASMQKLLLAGIAVNALCFAIVGMLTYISNDQQLRQFTLWT 178
Cdd:COG0609   84 IVLGGGL----SALGLPLAAFLGALLAALLVYLLARRgGGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRSIVFWL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 179 MGSLGQAQWQPLFIASTLILPACLYLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGL 258
Cdd:COG0609  160 MGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGL 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 737546409 259 VIPHLVRFKLGADHRWVLPASALCGAILLLIADTFARTAFAPAELPVGMITSFLGAPYFLWLVVRYR 325
Cdd:COG0609  240 VVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 24-323 1.22e-84

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 257.84  E-value: 1.22e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409   24 VGAFSLTWQDLVAA---DLNSNVWQIWLNIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSI 100
Cdd:pfam01032  12 IGAVKISPSDVFSAllgGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGAALGAVLAI 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  101 LLPNILptewGIYSTMLFAFMGSLAVTGFIYALS-HRTQASMQKLLLAGIAVNALCFAIVGMLTYISNDQQLRQFTLWTM 179
Cdd:pfam01032  92 LLGGSL----SLFALPLAAFIGALLAALLVYFLSrGRGGASPLRLILAGIAVSALLSALTSLLLLLLNPEALQSILFWLM 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  180 GSLGQAQWQPLFIASTLILPACLYLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLV 259
Cdd:pfam01032 168 GSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGFVGLI 247

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 737546409  260 IPHLVRFKLGADHRWVLPASALCGAILLLIADTFARTAFAPAELPVGMITSFLGAPYFLWLVVR 323
Cdd:pfam01032 248 VPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 43-328 3.01e-76

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 236.78  E-value: 3.01e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  43 VWQIwlniRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSILLPNILPTEWGIystMLFAFMG 122
Cdd:PRK03784  54 VWQL----RLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPPWAL---SLCAIAG 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 123 SLAVTGFIYALSHRTQASMQKLLLAGIAVNALCFAIVGMLTYISNDQQLRQFTLWTMGSLGQAQWQPLFIaSTLILPACL 202
Cdd:PRK03784 127 ALLITLILLRFARRHRLSTSRLLLAGVALGIICSALMTWAVYFSTSLDLRQLMYWMMGGFGGVDWRQSWL-MLALLPVLI 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 203 YLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLVIPHLVRFKLGADHRWVLPASALC 282
Cdd:PRK03784 206 WLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALA 285

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 737546409 283 GAILLLIADTFARTAFAPAELPVGMITSFLGAPYFLWLVVRYREVN 328
Cdd:PRK03784 286 GASLLLLADIVARLALASAELPIGVVTATLGAPVFIWLLLRSHRAR 331
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 55-321 3.90e-52

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 172.74  E-value: 3.90e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  55 ILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSILLPNILPtewgIYSTMLFAFMGSLAVTGFIYALS 134
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLS----NYALGAFAFAGALAIALLVLLLA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 135 HRTQASMQKLLLAGIAVNALCFAIVGMLTYISNDQqLRQFTLWTMGSLGQAQWQPLFIASTLILPACLYLFTLAQKLNVL 214
Cdd:cd06550   77 SRGGLSPSKLILIGIVLSAFFSAGVILISLLSDDS-LQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 215 QLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLVIPHLVRFKLGADHRWVLPASALCGAILLLIADTFA 294
Cdd:cd06550  156 TFDEDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLS 235

                        250       260
                 ....*....|....*....|....*..
gi 737546409 295 RTaFAPAELPVGMITSFLGAPYFLWLV 321
Cdd:cd06550  236 RT-LLPSELPVGPVTALLGAPYFLYLL 261
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 24-325 5.01e-110

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 322.02  E-value: 5.01e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  24 VGAFSLTWQDLVAA----DLNSNVWQIWLNIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALS 99
Cdd:COG0609    4 LGAVPISLSDVLRAllgpDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGAVLA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 100 ILLPNILptewGIYSTMLFAFMGSLAVTGFIYALSHR-TQASMQKLLLAGIAVNALCFAIVGMLTYISNDQQLRQFTLWT 178
Cdd:COG0609   84 IVLGGGL----SALGLPLAAFLGALLAALLVYLLARRgGGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRSIVFWL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 179 MGSLGQAQWQPLFIASTLILPACLYLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGL 258
Cdd:COG0609  160 MGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGL 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 737546409 259 VIPHLVRFKLGADHRWVLPASALCGAILLLIADTFARTAFAPAELPVGMITSFLGAPYFLWLVVRYR 325
Cdd:COG0609  240 VVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 24-323 1.22e-84

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 257.84  E-value: 1.22e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409   24 VGAFSLTWQDLVAA---DLNSNVWQIWLNIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSI 100
Cdd:pfam01032  12 IGAVKISPSDVFSAllgGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGAALGAVLAI 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  101 LLPNILptewGIYSTMLFAFMGSLAVTGFIYALS-HRTQASMQKLLLAGIAVNALCFAIVGMLTYISNDQQLRQFTLWTM 179
Cdd:pfam01032  92 LLGGSL----SLFALPLAAFIGALLAALLVYFLSrGRGGASPLRLILAGIAVSALLSALTSLLLLLLNPEALQSILFWLM 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  180 GSLGQAQWQPLFIASTLILPACLYLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLV 259
Cdd:pfam01032 168 GSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGFVGLI 247

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 737546409  260 IPHLVRFKLGADHRWVLPASALCGAILLLIADTFARTAFAPAELPVGMITSFLGAPYFLWLVVR 323
Cdd:pfam01032 248 VPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 39-325 5.26e-79

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 243.99  E-value: 5.26e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  39 LNSNVWQIWLNIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSILLPNILPTEWGIystMLF 118
Cdd:COG4139   43 LSEAWQLFVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPLAEPGLLGISNGAGVGLVLVVLLGGGLLPPWLL---SLA 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 119 AFMGSLAVTGFIYALSHRTQASMQkLLLAGIAVNALCFAIVGMLTYISNDQQLRQFTLWTMGSLGQAQWQPLFIASTLIl 198
Cdd:COG4139  120 AIAGALLVTLLLLAFARRRLSNAR-LLLIGVALGIICSAIMTWAVYFSSSLDLRQLMYWMMGSFGGVDWRQLWLLLALL- 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 199 PACLYLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLVIPHLVRFKLGADHRWVLPA 278
Cdd:COG4139  198 PVLLWLCLQGKPLNLLLLGENQARQLGLSVHRWRNLLVLATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPA 277

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 737546409 279 SALCGAILLLIADTFARTAFAPAELPVGMITSFLGAPYFLWLVVRYR 325
Cdd:COG4139  278 CALAGAALLLLADIIARLALSSAELPIGVVTATLGAPVFIWLLLRRR 324
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 43-328 3.01e-76

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 236.78  E-value: 3.01e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  43 VWQIwlniRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSILLPNILPTEWGIystMLFAFMG 122
Cdd:PRK03784  54 VWQL----RLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPPWAL---SLCAIAG 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 123 SLAVTGFIYALSHRTQASMQKLLLAGIAVNALCFAIVGMLTYISNDQQLRQFTLWTMGSLGQAQWQPLFIaSTLILPACL 202
Cdd:PRK03784 127 ALLITLILLRFARRHRLSTSRLLLAGVALGIICSALMTWAVYFSTSLDLRQLMYWMMGGFGGVDWRQSWL-MLALLPVLI 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 203 YLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLVIPHLVRFKLGADHRWVLPASALC 282
Cdd:PRK03784 206 WLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALA 285

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 737546409 283 GAILLLIADTFARTAFAPAELPVGMITSFLGAPYFLWLVVRYREVN 328
Cdd:PRK03784 286 GASLLLLADIVARLALASAELPIGVVTATLGAPVFIWLLLRSHRAR 331
btuC PRK09535
cobalamin ABC transporter permease BtuC;
28-327 7.33e-70

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 221.55  E-value: 7.33e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  28 SLTWQDLVAADLNSNVWQIWLNIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSILLPNILP 107
Cdd:PRK09535  72 DLEYASPFSFAVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLAVP 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 108 tewgiYSTMLFAFMGSLAVTGFIYALSHRT-QASMQKLLLAGIAVNALCFAIVGMLTYISNDQqLRQFTLWTMGSLGQAQ 186
Cdd:PRK09535 152 -----FGLQAAAFAGALVAAFGVYAIATENgRTPVATLLLAGVAVQTFLGAVISYLLLHSGES-LRRAVYWLMGHLHGST 225

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 187 WQPLFIASTLILPACLYLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLVIPHLVRF 266
Cdd:PRK09535 226 WSDVEVALPVVVVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRL 305

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 737546409 267 KLGADHRWVLPASALCGAILLLIADTFARTafAPAELPVGMITSFLGAPYFLWLVVRyREV 327
Cdd:PRK09535 306 LVGPDHRILLPTSALAGASFLVATDTVARS--GPAEVPVGIVTAALGAPFFLYLLRT-REV 363
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 24-323 2.41e-60

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 196.50  E-value: 2.41e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  24 VGAFSLTWQDLVAA---DLNSNVWQIWLNIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSI 100
Cdd:COG4779   43 LGDYPLSPGDVLRAllgEGDPGASFVVLELRLPRALAALLVGAALGLSGAIFQSLTRNPLASPDIIGITAGASAGAVAAI 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 101 LLPNilpteWGIYSTMLFAFMGSLAVTGFIYALSHRTQASMQKLLLAGIAVNALCFAIVGMLTYISNDQQLRQFTLWTMG 180
Cdd:COG4779  123 VVLG-----GSGLAVALGALAGGLATALLVYLLAWRGGVSGYRLILVGIGVSAMLTAVNSYLLTRADLEDAQSAAVWLTG 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 181 SLGQAQWQ---PLFIASTLILPACLYLftlAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIG 257
Cdd:COG4779  198 SLNGRTWEdvlPLAVALAVLLPLALAL---ARRLRLLELGDDTAAALGVRVERTRLLLLLVAVALAAVATAAAGPIAFVA 274

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 737546409 258 LVIPHLVRfKLGADHRWVLPASALCGAILLLIADTFARTAFAPAELPVGMITSFLGAPYFLWLVVR 323
Cdd:COG4779  275 LAAPQIAR-RLTRSPGPPLLPSALVGALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYLLWLLIR 339
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
30-323 2.44e-56

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 185.67  E-value: 2.44e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  30 TWQDLVAADLNSNVWQIWLNIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSILLpniLPTE 109
Cdd:PRK11228  30 ALNALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTSAL---SPTP 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 110 WGIYSTMLFAFMGSLAVTGFIYALSH--RTQASMQKLLLAGIAVNALCFAIVGMLTYISNDQQLRQFTlWTMGSLGQAQW 187
Cdd:PRK11228 107 FAGYSLAFIAACGGGLSWLLVMTAGGgwRHTHDRNRLILAGIALSALCMALTRITLLLAEDHAYGIFY-WLAGGVSHARW 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 188 QPLFIASTLILPACLYLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLVIPHLVRFK 267
Cdd:PRK11228 186 QEVWQLLPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFW 265

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 737546409 268 LGADHRWVLPASALCGAILLLIADTFARTAFAPAELPVGMITSFLGAPYFLWLVVR 323
Cdd:PRK11228 266 IGYDQRNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCFVWLARR 321
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
25-325 7.55e-55

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 181.40  E-value: 7.55e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  25 GAFSLTWQDLVAADLNSNVWQIWL-NIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLA-VALSILL 102
Cdd:PRK09777  24 GVIPLPWRALLTDWQAGDEHYYVLmEYRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPDILGVNHAASLAsVGALLLF 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 103 PNiLPTEWgiysTMLFAFMGSLAvtGFIYALSHRTQASMQKLLLAGIAVNALCFAIVGMLTyISNDQQLRQFTLWTMGSL 182
Cdd:PRK09777 104 PS-LPVMW----LPLLAFIGGMA--GLILLKMLAGTHQPMKLALTGVALSALWASLTDYLM-LSRPQDINNALLWLTGSL 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 183 GQAQWQPLFIASTLILPACLYLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLVIPH 262
Cdd:PRK09777 176 WGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVALTATGVAACGPISFIGLVVPH 255

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 737546409 263 LVRFKLGADHRWVLPASALCGAILLLIADTFARTAFAPAELPVGMITSFLGAPYFLWLVVRYR 325
Cdd:PRK09777 256 LMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLLVRMR 318
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
42-323 4.06e-54

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 187.35  E-value: 4.06e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  42 NVWQIWLNIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSILLPNILPTEWgiysTMLFAFM 121
Cdd:PRK10577 388 QLLDALLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAGFGW----LLAAALL 463

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 122 GSLAVTGFIYALSHRTQASMQKLLLAGIAVNALCFAIVGMLTyISNDQQLRQFTLWTMGSLGQAQW---QPLFIASTLIL 198
Cdd:PRK10577 464 GALAALALILLLARRGGFAPERLLLTGIALSALFTALIQLLL-ASGDPRAAQLLTWLSGSTYGVTWaqaLPLLIVAVLLL 542

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 199 PACLYLftlAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLVIPHLVRFKLGADHRWVLPA 278
Cdd:PRK10577 543 ALALLL---RRWLDLLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVL 619

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 737546409 279 SALCGAILLLIADTFARTAFAPAELPVGMITSFLGAPYFLWLVVR 323
Cdd:PRK10577 620 AALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRR 664
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
27-325 1.48e-52

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 183.12  E-value: 1.48e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  27 FSLTWQDLVAADLNSNVWQIWLNIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSILLpniL 106
Cdd:PRK10577  38 LSQWLQALWGPDADDLEQLLLHYSRLPRLAIALLVGAALGLAGALLQQVLRNPLASPTTLGVAAGAQLALVLATLF---A 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 107 PTEWGIYStMLFAFMGSLAVTGFIYALSHRTQASMQKLLLAGIAVNALCFAIVGMLTyISNDQQLRQFTLWTMGSLGQAQ 186
Cdd:PRK10577 115 PALLALAS-QLAAFAGGLLAAALVFALAGGKRLSPLRLVLAGMVVSLYLGALTTLLL-LFNEQYLQGLFLWGAGSLAQND 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 187 WQPLFIASTLILPACLYLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLVIPHLVRF 266
Cdd:PRK10577 193 WSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALALAVLLSAAVVSAVGPIGFIGLAAPNLARL 272

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 737546409 267 KLGADHRWVLPASALCGAILLLIADTFAR--TAFAPAELPVGMITSFLGAPYFLWLVVRYR 325
Cdd:PRK10577 273 LGARRLRARLPLSPLIGALLLLLTDQLVRllAGVGGELLPTGAVTALIGAPLLLWLLPRLR 333
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 55-321 3.90e-52

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 172.74  E-value: 3.90e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  55 ILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSILLPNILPtewgIYSTMLFAFMGSLAVTGFIYALS 134
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLS----NYALGAFAFAGALAIALLVLLLA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 135 HRTQASMQKLLLAGIAVNALCFAIVGMLTYISNDQqLRQFTLWTMGSLGQAQWQPLFIASTLILPACLYLFTLAQKLNVL 214
Cdd:cd06550   77 SRGGLSPSKLILIGIVLSAFFSAGVILISLLSDDS-LQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 215 QLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLVIPHLVRFKLGADHRWVLPASALCGAILLLIADTFA 294
Cdd:cd06550  156 TFDEDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLS 235

                        250       260
                 ....*....|....*....|....*..
gi 737546409 295 RTaFAPAELPVGMITSFLGAPYFLWLV 321
Cdd:cd06550  236 RT-LLPSELPVGPVTALLGAPYFLYLL 261
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
27-325 3.07e-44

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 154.48  E-value: 3.07e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  27 FSLTWQDLVAADLNSNVwQIWLNIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSILLpnil 106
Cdd:PRK10441  37 ASVVLEALSGTCQSADC-TIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAAL---- 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 107 pteWGIYST---MLFAFMGSLAVTGFIYALSHR--TQASMQKLLLAGIAVNALCFAIVGMLTYIsNDQQLRQFTLWTMGS 181
Cdd:PRK10441 112 ---FGYSSAqeqLAMAFAGALVASLIVAFTGSQggGQLSPVRLTLAGVALAAVLEGLTSGIALL-NPDVYDQLRFWQAGS 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 182 LGQAQWQPLFIASTLILPACLYLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLVIP 261
Cdd:PRK10441 188 LDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMP 267

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 737546409 262 HLVRFKLGADHRWVLPASALCGAILLLIADTFARTaFAPAELPVGMITSFLGAPYFLWLVVRYR 325
Cdd:PRK10441 268 HMARWLVGADHRWSLPVTLLATPALLLFADIIGRL-LVPGELRVSVVSAFIGAPVLIFLVRRKT 330
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
24-323 3.07e-40

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 143.70  E-value: 3.07e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409  24 VGAFSLTWQDLVAA---DLNSNVWQIWLNIRLPRILLAIIVGLALAVSGTVFQGLFHNPMADPALIGVNSGASLAVALSI 100
Cdd:PRK10440  29 SGAVTLETSQVFAAlmgDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAM 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 101 LLPNilpteWGIYSTMLFAFMGSLAVTGFIYALSHRTQASMQKLLLAGIAVNALCFAIVGMLTYISNDQQLRQFTLWTMG 180
Cdd:PRK10440 109 VLFG-----QDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTAGLWNAG 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737546409 181 SLGQAQWQPLFIASTLILPACLYLFTLAQKLNVLQLGDEEAHYLGINVLQLKRLLMLLGALLVGSAVAVSGAIGFIGLVI 260
Cdd:PRK10440 184 SLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLMLVAVVLTAAATALAGPISFIALVA 263

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 737546409 261 PHLVRFKLGADhRWVLPASALCGAILLLIADTFARTAFAPAELPVGMITSFLGAPYFLWLVVR 323
Cdd:PRK10440 264 PHIARRLSGTA-RWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQ 325
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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