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Conserved domains on  [gi|737994220|ref|WP_035956001|]
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MULTISPECIES: helix-turn-helix transcriptional regulator [Burkholderia]

Protein Classification

ArsR/SmtB family transcription factor( domain architecture ID 10001925)

ArsR (Arsenical Resistance Operon Repressor)/SmtB family transcription factor is a winged-helix-turn-helix transcriptional regulator that may be metal-sensing and modulate the expression of genes associated with metal homeostasis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ArsR COG0640
DNA-binding transcriptional regulator, ArsR family [Transcription];
8-83 2.47e-26

DNA-binding transcriptional regulator, ArsR family [Transcription];


:

Pssm-ID: 440405 [Multi-domain]  Cd Length: 92  Bit Score: 93.42  E-value: 2.47e-26
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 737994220   8 LFRTLADPTRRALFERLCEeGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYSAQPHALAPLIDW 83
Cdd:COG0640   13 LFKALADPTRLRILRLLAE-GELCVGELAEALGLSQSTVSHHLKVLREAGLVTSRREGRWVYYRLADEALAELLEW 87
 
Name Accession Description Interval E-value
ArsR COG0640
DNA-binding transcriptional regulator, ArsR family [Transcription];
8-83 2.47e-26

DNA-binding transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 440405 [Multi-domain]  Cd Length: 92  Bit Score: 93.42  E-value: 2.47e-26
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 737994220   8 LFRTLADPTRRALFERLCEeGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYSAQPHALAPLIDW 83
Cdd:COG0640   13 LFKALADPTRLRILRLLAE-GELCVGELAEALGLSQSTVSHHLKVLREAGLVTSRREGRWVYYRLADEALAELLEW 87
HTH_metalloreg NF033788
metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense ...
8-81 6.05e-25

metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense toxic heavy metals such as arsenic or cadmium, and are released from DNA so that resistance factors will be expressed, include ArsR, SmtB, ZiaR, CadC, CadX, KmtR, etc. However, some members of this family, including the sporulation delaying system autorepressor SdpR and its family (see NF033789), may lack metal-binding cites and instead regulate other cellular processes.


Pssm-ID: 411368 [Multi-domain]  Cd Length: 76  Bit Score: 89.06  E-value: 6.05e-25
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 737994220   8 LFRTLADPTRRALFERLCEeGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYSAQPHALAPLI 81
Cdd:NF033788   4 LFKALADPTRLRILELLAE-GELCVCELAEALGLSQSAVSQHLKVLRDAGLVTSRREGRWVYYRLADEHVAELL 76
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
9-72 3.39e-17

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 69.63  E-value: 3.39e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 737994220   9 FRTLADPTRRALFERLcEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYSA 72
Cdd:cd00090    1 LKALSDPTRLRILRLL-LEGPLTVSELAERLGLSQSTVSRHLKKLEEAGLVESRREGRRVYYSL 63
repress_SdpR NF033789
autorepressor SdpR family transcription factor; Transcription factors in the family of the ...
9-71 3.11e-16

autorepressor SdpR family transcription factor; Transcription factors in the family of the sporulation delaying system autorepressor SdpR (of Bacillus subtilis) resemble metalloregulatory transcriptional repressors such as ArsR, SmtB, CadX, ZiaR, etc., but may lack the key metal-binding residues.


Pssm-ID: 411369 [Multi-domain]  Cd Length: 79  Bit Score: 67.05  E-value: 3.11e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 737994220   9 FRTLADPTRRALFERLcEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYS 71
Cdd:NF033789   2 FKALSDPTRREILELL-KEGDMTAGEIAEHFDMSKPSISHHLNILKQADLVTDERKGQFIYYS 63
PRK10141 PRK10141
DNA-binding transcriptional repressor ArsR; Provisional
8-75 1.03e-14

DNA-binding transcriptional repressor ArsR; Provisional


Pssm-ID: 236654  Cd Length: 117  Bit Score: 64.45  E-value: 1.03e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 737994220   8 LFRTLADPTRRALFERLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYSAQPH 75
Cdd:PRK10141   9 LFKILSDETRLGIVLLLRESGELCVCDLCTALDQSQPKISRHLALLRESGLLLDRKQGKWVHYRLSPH 76
HTH_ARSR smart00418
helix_turn_helix, Arsenical Resistance Operon Repressor;
23-81 2.28e-14

helix_turn_helix, Arsenical Resistance Operon Repressor;


Pssm-ID: 197713 [Multi-domain]  Cd Length: 66  Bit Score: 62.23  E-value: 2.28e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 737994220    23 RLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYSAQPHALAPLI 81
Cdd:smart00418   4 KLLAEGELCVCELAEILGLSQSTVSHHLKKLREAGLVESRREGKRVYYSLTDEKVADLL 62
HTH_20 pfam12840
Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in ...
6-66 4.65e-14

Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.


Pssm-ID: 432824 [Multi-domain]  Cd Length: 61  Bit Score: 61.02  E-value: 4.65e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 737994220    6 DLLFRTLADPTRRALFERLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGR 66
Cdd:pfam12840   1 DDVAEALADPTRLRILRALVGDEPLTASELARRLDISRNTLSYHLRKLEEAGLVEVVREGR 61
cas_HTH TIGR01884
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are ...
5-60 5.84e-03

CRISPR locus-related DNA-binding protein; Most but not all examples of this family are associated with CRISPR loci, a combination of DNA repeats and characteristic proteins encoded near the repeat cluster. The C-terminal region of this protein is homologous to DNA-binding helix-turn-helix domains with predicted transcriptional regulatory activity. [Regulatory functions, DNA interactions, , ]


Pssm-ID: 273852 [Multi-domain]  Cd Length: 203  Bit Score: 34.25  E-value: 5.84e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 737994220    5 QDLLFRT-LADPTRRAL--FERLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVS 60
Cdd:TIGR01884 130 IDLDLVPlLAGLSREELkiLEVLKATGEKSVKNIAKKLGKSLSTISRHLAELEKKGLVE 188
 
Name Accession Description Interval E-value
ArsR COG0640
DNA-binding transcriptional regulator, ArsR family [Transcription];
8-83 2.47e-26

DNA-binding transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 440405 [Multi-domain]  Cd Length: 92  Bit Score: 93.42  E-value: 2.47e-26
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 737994220   8 LFRTLADPTRRALFERLCEeGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYSAQPHALAPLIDW 83
Cdd:COG0640   13 LFKALADPTRLRILRLLAE-GELCVGELAEALGLSQSTVSHHLKVLREAGLVTSRREGRWVYYRLADEALAELLEW 87
HTH_metalloreg NF033788
metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense ...
8-81 6.05e-25

metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense toxic heavy metals such as arsenic or cadmium, and are released from DNA so that resistance factors will be expressed, include ArsR, SmtB, ZiaR, CadC, CadX, KmtR, etc. However, some members of this family, including the sporulation delaying system autorepressor SdpR and its family (see NF033789), may lack metal-binding cites and instead regulate other cellular processes.


Pssm-ID: 411368 [Multi-domain]  Cd Length: 76  Bit Score: 89.06  E-value: 6.05e-25
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 737994220   8 LFRTLADPTRRALFERLCEeGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYSAQPHALAPLI 81
Cdd:NF033788   4 LFKALADPTRLRILELLAE-GELCVCELAEALGLSQSAVSQHLKVLRDAGLVTSRREGRWVYYRLADEHVAELL 76
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
9-72 3.39e-17

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 69.63  E-value: 3.39e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 737994220   9 FRTLADPTRRALFERLcEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYSA 72
Cdd:cd00090    1 LKALSDPTRLRILRLL-LEGPLTVSELAERLGLSQSTVSRHLKKLEEAGLVESRREGRRVYYSL 63
repress_SdpR NF033789
autorepressor SdpR family transcription factor; Transcription factors in the family of the ...
9-71 3.11e-16

autorepressor SdpR family transcription factor; Transcription factors in the family of the sporulation delaying system autorepressor SdpR (of Bacillus subtilis) resemble metalloregulatory transcriptional repressors such as ArsR, SmtB, CadX, ZiaR, etc., but may lack the key metal-binding residues.


Pssm-ID: 411369 [Multi-domain]  Cd Length: 79  Bit Score: 67.05  E-value: 3.11e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 737994220   9 FRTLADPTRRALFERLcEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYS 71
Cdd:NF033789   2 FKALSDPTRREILELL-KEGDMTAGEIAEHFDMSKPSISHHLNILKQADLVTDERKGQFIYYS 63
PRK10141 PRK10141
DNA-binding transcriptional repressor ArsR; Provisional
8-75 1.03e-14

DNA-binding transcriptional repressor ArsR; Provisional


Pssm-ID: 236654  Cd Length: 117  Bit Score: 64.45  E-value: 1.03e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 737994220   8 LFRTLADPTRRALFERLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYSAQPH 75
Cdd:PRK10141   9 LFKILSDETRLGIVLLLRESGELCVCDLCTALDQSQPKISRHLALLRESGLLLDRKQGKWVHYRLSPH 76
HTH_ARSR smart00418
helix_turn_helix, Arsenical Resistance Operon Repressor;
23-81 2.28e-14

helix_turn_helix, Arsenical Resistance Operon Repressor;


Pssm-ID: 197713 [Multi-domain]  Cd Length: 66  Bit Score: 62.23  E-value: 2.28e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 737994220    23 RLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYSAQPHALAPLI 81
Cdd:smart00418   4 KLLAEGELCVCELAEILGLSQSTVSHHLKKLREAGLVESRREGKRVYYSLTDEKVADLL 62
COG1777 COG1777
Predicted transcriptional regulator, ArsR family [Transcription];
1-66 3.00e-14

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441383  Cd Length: 113  Bit Score: 63.13  E-value: 3.00e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 737994220   1 MQNAQDL--LFRTLADPTRRALFERLCEEgELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGR 66
Cdd:COG1777    1 MSDDEDLdrLLDALGNPTRRRILALLSEE-PAYVSELARELGVSRQAVYKHLRKLEEAGLVESYREGR 67
HTH_20 pfam12840
Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in ...
6-66 4.65e-14

Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.


Pssm-ID: 432824 [Multi-domain]  Cd Length: 61  Bit Score: 61.02  E-value: 4.65e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 737994220    6 DLLFRTLADPTRRALFERLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGR 66
Cdd:pfam12840   1 DDVAEALADPTRLRILRALVGDEPLTASELARRLDISRNTLSYHLRKLEEAGLVEVVREGR 61
COG3398 COG3398
Predicted transcriptional regulator, contains two HTH domains [Transcription];
12-77 6.59e-12

Predicted transcriptional regulator, contains two HTH domains [Transcription];


Pssm-ID: 442625 [Multi-domain]  Cd Length: 159  Bit Score: 57.97  E-value: 6.59e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 737994220  12 LADPTRRALFERLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGRQTHYSAQPHAL 77
Cdd:COG3398   94 LRRETPRRILLYLLENPGATNKELAEELGISRSTVSWHLKRLEEDGLVERERDGRNVRYYLNPPER 159
HTH_5 pfam01022
Bacterial regulatory protein, arsR family; Members of this family contains a DNA binding ...
14-59 1.07e-10

Bacterial regulatory protein, arsR family; Members of this family contains a DNA binding 'helix-turn-helix' motif. This family includes other proteins which are not included in the Prosite definition.


Pssm-ID: 425993 [Multi-domain]  Cd Length: 45  Bit Score: 52.06  E-value: 1.07e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 737994220   14 DPTRRALFERLCEeGELTVAALTAHAGVSQPAVSKHLGVLKQAGLV 59
Cdd:pfam01022   1 DPTRLKILKLLAE-GELCVCELAEELGLSQSTVSHHLKKLREAGLV 45
COG2345 COG2345
Predicted transcriptional regulator, ArsR family [Transcription];
10-66 3.43e-07

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441914 [Multi-domain]  Cd Length: 217  Bit Score: 46.07  E-value: 3.43e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 737994220  10 RTLADPTRRALFERLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGR 66
Cdd:COG2345    8 AALADPTRRRILELLKRAGPVTAAELAEALGLTPNAVRRHLDALEEEGLVERETERR 64
YrhO COG1378
Sugar-specific transcriptional regulator TrmB [Transcription];
24-105 2.24e-05

Sugar-specific transcriptional regulator TrmB [Transcription];


Pssm-ID: 440988 [Multi-domain]  Cd Length: 238  Bit Score: 41.16  E-value: 2.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737994220  24 LCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSdRHEGRQTHYSAQP--HALAPLIDWtsqmagfWQARFDALEDL 101
Cdd:COG1378   22 LLELGPATASELAKASGVPRSRVYDVLESLEEKGLVE-VSEGRPKRYRAVPpeEALERLLEE-------REEELEELREE 93

                 ....
gi 737994220 102 LKRM 105
Cdd:COG1378   94 LEEL 97
MarR_2 pfam12802
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
18-67 2.29e-04

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 432797 [Multi-domain]  Cd Length: 60  Bit Score: 36.41  E-value: 2.29e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 737994220   18 RALFErLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLV---SDRHEGRQ 67
Cdd:pfam12802   9 RVLLA-LARNPGLTVAELARRLGISKQTVSRLVKRLEAKGLVerePSPADRRA 60
COG4190 COG4190
Predicted transcriptional regulator, contains HTH domain [Transcription];
6-66 2.37e-04

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 443344  Cd Length: 121  Bit Score: 37.57  E-value: 2.37e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 737994220   6 DLLFRTLAdPTRRALFERLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSDRHEGR 66
Cdd:COG4190   44 ESLARVLT-PKRLELLRAIAEEGPESIRELARRLGRDVKNVHRDLKTLEELGLVELEEDGR 103
HTH_24 pfam13412
Winged helix-turn-helix DNA-binding;
16-59 6.59e-04

Winged helix-turn-helix DNA-binding;


Pssm-ID: 404317 [Multi-domain]  Cd Length: 45  Bit Score: 34.72  E-value: 6.59e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 737994220   16 TRRALFERLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLV 59
Cdd:pfam13412   2 TDRKILNLLQENPRISQRELAERLGLSPSTVNRRLKRLEEEGVI 45
COG4742 COG4742
Predicted transcriptional regulator, contains HTH domain [Transcription];
6-66 8.60e-04

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 443776 [Multi-domain]  Cd Length: 267  Bit Score: 36.80  E-value: 8.60e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 737994220   6 DLLFRTladPTRRALFERLcEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVSdRHEGR 66
Cdd:COG4742   10 DFLFLS---EKRKNILLLL-AEGPKTRSELAESLDVSRSTILRQLKELEERGLIE-RDDGE 65
CasRa_I-A cd09655
CRISPR/Cas system-associated transcriptional regulator CasRa; CRISPR (Clustered Regularly ...
5-60 3.27e-03

CRISPR/Cas system-associated transcriptional regulator CasRa; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Predicted transcriptional regulator of CRISPR/Cas system


Pssm-ID: 187786 [Multi-domain]  Cd Length: 198  Bit Score: 35.05  E-value: 3.27e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 737994220   5 QDLLFRTL-ADPTRRAL--FERLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVS 60
Cdd:cd09655  126 IELDLVPLlAGLSREELkiLEVLKAKGEKSVKNIAKKLGKSLSTISRHLRELEKKGLVE 184
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
24-105 5.36e-03

DNA-binding transcriptional regulator, MarR family [Transcription];


Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 34.18  E-value: 5.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 737994220  24 LCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVS---DRHEGRQTHYS-------AQPHALAPLIDWTSQ-MAGFWQ 92
Cdd:COG1846   47 LAEAGGLTQSELAERLGLTKSTVSRLLDRLEEKGLVErepDPEDRRAVLVRltekgraLLEEARPALEALLAElLAGLSE 126
                         90
                 ....*....|...
gi 737994220  93 ARFDALEDLLKRM 105
Cdd:COG1846  127 EELEALLRLLRRL 139
cas_HTH TIGR01884
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are ...
5-60 5.84e-03

CRISPR locus-related DNA-binding protein; Most but not all examples of this family are associated with CRISPR loci, a combination of DNA repeats and characteristic proteins encoded near the repeat cluster. The C-terminal region of this protein is homologous to DNA-binding helix-turn-helix domains with predicted transcriptional regulatory activity. [Regulatory functions, DNA interactions, , ]


Pssm-ID: 273852 [Multi-domain]  Cd Length: 203  Bit Score: 34.25  E-value: 5.84e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 737994220    5 QDLLFRT-LADPTRRAL--FERLCEEGELTVAALTAHAGVSQPAVSKHLGVLKQAGLVS 60
Cdd:TIGR01884 130 IDLDLVPlLAGLSREELkiLEVLKATGEKSVKNIAKKLGKSLSTISRHLAELEKKGLVE 188
LexA COG1974
SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) [Transcription, ...
31-100 7.35e-03

SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) [Transcription, Signal transduction mechanisms];


Pssm-ID: 441577 [Multi-domain]  Cd Length: 199  Bit Score: 34.12  E-value: 7.35e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 737994220  31 TVAALTAHAGVSQPAVSKHLGVLKQAG-LVSDRHEGRQTHYSAQPHALA--PLIDWTSqmAGFWQARFDALED 100
Cdd:COG1974   27 SQREIAEALGLSSSAVHRHLKALEKKGyLRRDPGKSRAIELLPASPEVVglPLLGRVA--AGFPIPAEENIEE 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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