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Conserved domains on  [gi|738157201|ref|WP_036114537|]
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MULTISPECIES: YciI family protein [Gammaproteobacteria]

Protein Classification

YciI family protein( domain architecture ID 10006398)

YciI family protein similar to Haemophilus influenzae YciI (HI0828) and Burkholderia phenoliruptrix 5-chlorohydroxyhydroquinone dehydrochlorinase, which is involved in the biodegradation of 2,4,5-trichlorophenoxyacetate

CATH:  3.30.70.1060

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YciI COG2350
YciI superfamily enzyme, includes 5-CHQ dehydrochlorinase, contains active-site pHis ...
 1-93 1.00e-20

YciI superfamily enzyme, includes 5-CHQ dehydrochlorinase, contains active-site pHis [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


:

Pssm-ID: 441917  Cd Length: 93  Bit Score: 79.10  E-value: 1.00e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738157201   1 MHIYIVRMDHPDGRG-WNTFVREHVIYLKGLIEQGKLLASGPLKNTPLRaGFLIFRAETRDEVQSMIGADPFAREGLIAH 79
Cdd:COG2350    1 MLFAVILTDKPDSLEeRDALRPAHLAYLKELYEEGRLLAAGPLLDDDTG-GLIIAEADSREEAEALAAADPYVKAGVVAS 79

                         90
                 ....*....|....
gi 738157201  80 LDIQQWDPLFGQLS 93
Cdd:COG2350   80 VEVREWKPVLGALA 93
 
Name Accession Description Interval E-value
YciI COG2350
YciI superfamily enzyme, includes 5-CHQ dehydrochlorinase, contains active-site pHis ...
 1-93 1.00e-20

YciI superfamily enzyme, includes 5-CHQ dehydrochlorinase, contains active-site pHis [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 441917  Cd Length: 93  Bit Score: 79.10  E-value: 1.00e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738157201   1 MHIYIVRMDHPDGRG-WNTFVREHVIYLKGLIEQGKLLASGPLKNTPLRaGFLIFRAETRDEVQSMIGADPFAREGLIAH 79
Cdd:COG2350    1 MLFAVILTDKPDSLEeRDALRPAHLAYLKELYEEGRLLAAGPLLDDDTG-GLIIAEADSREEAEALAAADPYVKAGVVAS 79

                         90
                 ....*....|....
gi 738157201  80 LDIQQWDPLFGQLS 93
Cdd:COG2350   80 VEVREWKPVLGALA 93
PRK12863 PRK12863
YciI-like protein; Reviewed
 1-92 9.81e-13

YciI-like protein; Reviewed


Pssm-ID: 183800  Cd Length: 94  Bit Score: 58.76  E-value: 9.81e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738157201   1 MHIYIVRMDHPDGRGWNTFVR-EHVIYLKGLieQGKLLASGPL---KNTPLRAGFLIFRAETRDEVQSMIGADPFAREGL 76
Cdd:PRK12863   1 MLFAILCTDKPGHLEVRLATRpAHLAYLETL--EGRLLAAGPLlddDGKPMVGSLVVVEAESRAAAEAFAAADPFAKAGL 78

                         90
                 ....*....|....*.
gi 738157201  77 IAHLDIQQWDPLFGQL 92
Cdd:PRK12863  79 YESVDIKPFNKAFGNG 94
YCII pfam03795
YCII-related domain; The majority of proteins in this family consist of a single copy of this ...
 22-85 5.50e-12

YCII-related domain; The majority of proteins in this family consist of a single copy of this domain, though it is also found as a repeat. A strongly conserved histidine and a aspartate suggest that the domain has an enzymatic function. This family also now includes the family formerly known as the DGPF domain (COG3795). Although its function is unknown it is found fused to a sigma-70 factor family domain in Swiss:Q9A8M4. Suggesting that this domain plays a role in transcription initiation (Bateman A per. obs.). This domain is named after the most conserved motif in the alignment.


Pssm-ID: 397734  Cd Length: 94  Bit Score: 56.98  E-value: 5.50e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 738157201   22 EHVIYLKGLIEQGKLLASGPLKNT--------PLRAGFLIFRAETRDEVQSMIGADPFAREGLIAHLDIQQW 85
Cdd:pfam03795  22 AHLAYLEQLKKEGVLLASGPTLVIdgpfaetkEQLGGFYIIEAADLDEAIAIAAGDPFVAAGLYEERPVKEF 93
 
Name Accession Description Interval E-value
YciI COG2350
YciI superfamily enzyme, includes 5-CHQ dehydrochlorinase, contains active-site pHis ...
 1-93 1.00e-20

YciI superfamily enzyme, includes 5-CHQ dehydrochlorinase, contains active-site pHis [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 441917  Cd Length: 93  Bit Score: 79.10  E-value: 1.00e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738157201   1 MHIYIVRMDHPDGRG-WNTFVREHVIYLKGLIEQGKLLASGPLKNTPLRaGFLIFRAETRDEVQSMIGADPFAREGLIAH 79
Cdd:COG2350    1 MLFAVILTDKPDSLEeRDALRPAHLAYLKELYEEGRLLAAGPLLDDDTG-GLIIAEADSREEAEALAAADPYVKAGVVAS 79

                         90
                 ....*....|....
gi 738157201  80 LDIQQWDPLFGQLS 93
Cdd:COG2350   80 VEVREWKPVLGALA 93
PRK12863 PRK12863
YciI-like protein; Reviewed
 1-92 9.81e-13

YciI-like protein; Reviewed


Pssm-ID: 183800  Cd Length: 94  Bit Score: 58.76  E-value: 9.81e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738157201   1 MHIYIVRMDHPDGRGWNTFVR-EHVIYLKGLieQGKLLASGPL---KNTPLRAGFLIFRAETRDEVQSMIGADPFAREGL 76
Cdd:PRK12863   1 MLFAILCTDKPGHLEVRLATRpAHLAYLETL--EGRLLAAGPLlddDGKPMVGSLVVVEAESRAAAEAFAAADPFAKAGL 78

                         90
                 ....*....|....*.
gi 738157201  77 IAHLDIQQWDPLFGQL 92
Cdd:PRK12863  79 YESVDIKPFNKAFGNG 94
YCII pfam03795
YCII-related domain; The majority of proteins in this family consist of a single copy of this ...
 22-85 5.50e-12

YCII-related domain; The majority of proteins in this family consist of a single copy of this domain, though it is also found as a repeat. A strongly conserved histidine and a aspartate suggest that the domain has an enzymatic function. This family also now includes the family formerly known as the DGPF domain (COG3795). Although its function is unknown it is found fused to a sigma-70 factor family domain in Swiss:Q9A8M4. Suggesting that this domain plays a role in transcription initiation (Bateman A per. obs.). This domain is named after the most conserved motif in the alignment.


Pssm-ID: 397734  Cd Length: 94  Bit Score: 56.98  E-value: 5.50e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 738157201   22 EHVIYLKGLIEQGKLLASGPLKNT--------PLRAGFLIFRAETRDEVQSMIGADPFAREGLIAHLDIQQW 85
Cdd:pfam03795  22 AHLAYLEQLKKEGVLLASGPTLVIdgpfaetkEQLGGFYIIEAADLDEAIAIAAGDPFVAAGLYEERPVKEF 93
PRK12864 PRK12864
YciI-like protein; Reviewed
 19-85 3.48e-08

YciI-like protein; Reviewed


Pssm-ID: 183801  Cd Length: 89  Bit Score: 46.87  E-value: 3.48e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 738157201  19 FVREHVIYLKGLIEQGKLLASGPLKNTplRAGFLIFRAETRDEVQSMIGADPFAREGLIAHLDIQQW 85
Cdd:PRK12864  21 FREAHLDRLAKLKEQGILITLGPTKDL--TYVFGIFEAEDEETVRQLIEADPYWQNGIWTEYEVYPW 85
PRK12866 PRK12866
YciI-like protein; Reviewed
 1-85 3.20e-07

YciI-like protein; Reviewed


Pssm-ID: 237238  Cd Length: 97  Bit Score: 44.72  E-value: 3.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738157201   1 MH---IYIVRMDHPDGRGwnTFVREHVIYLKGLIEQGKLLASGPLKNTPLRAgFLIFRAETRDEVQSMIGADPFAREGLI 77
Cdd:PRK12866   1 MHyllTYDLVDDYLERRE--AYRAEHLALAQAATERGELLLAGALADPADGA-VLVFEGDSPAAAEAFARADPYVRNGLV 77


                 ....*...
gi 738157201  78 AHLDIQQW 85
Cdd:PRK12866  78 KSWRVRPW 85
PRK12865 PRK12865
YciI-like protein; Reviewed
 6-89 9.90e-07

YciI-like protein; Reviewed


Pssm-ID: 171782  Cd Length: 97  Bit Score: 43.28  E-value: 9.90e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738157201   6 VRMD-HPDgrgwntfvreHVIYLKGLIEQGKLLASGPLKNTPLRA--GFLIFRAETRDEVQSMIGADPFAREGLIAHLDI 82
Cdd:PRK12865  16 VRMDtRPT----------HLEYLNKLNAEGTLKIAGPFLDDDGKPcgSLVIVKAETKEAAKALADADPYAKAGLFESVEV 85


                 ....*..
gi 738157201  83 QQWDPLF 89
Cdd:PRK12865  86 KAYNWVF 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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