|
Name |
Accession |
Description |
Interval |
E-value |
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
10-241 |
1.05e-99 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 292.74 E-value: 1.05e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD--RSVRQ 87
Cdd:COG1131 1 IEVRGLTKRY-------GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARdpAEVRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 88 RIGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKtaQKKQLRQYSKGMMQRIGIAQALINDPE 167
Cdd:COG1131 74 RIGYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDA--ADRKVGTLSGGMKQRLGLALALLHDPE 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 168 LVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRA--DVY 241
Cdd:COG1131 152 LLILDEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARLleDVF 227
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
10-225 |
7.56e-79 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 237.30 E-value: 7.56e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDR--SVRQ 87
Cdd:cd03230 1 IEVRNLSKRY-------GKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEpeEVKR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 88 RIGYLPENAYYYDYLTGWEFLqliggifqilssvqkkripelldlvgldrktaqkkqlrQYSKGMMQRIGIAQALINDPE 167
Cdd:cd03230 74 RIGYLPEEPSLYENLTVRENL--------------------------------------KLSGGMKQRLALAQALLHDPE 115
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 168 LVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:cd03230 116 LLILDEPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
9-246 |
2.35e-69 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 215.88 E-value: 2.35e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI--GDRSVR 86
Cdd:COG4555 1 MIEVENLSKKY-------GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVrkEPREAR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 87 QRIGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKtaQKKQLRQYSKGMMQRIGIAQALINDP 166
Cdd:COG4555 74 RQIGVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEF--LDRRVGELSTGMKKKVALARALVHDP 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 167 ELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL---GRADVYQV 243
Cdd:COG4555 152 KVLLLDEPTNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELReeiGEENLEDA 231
|
...
gi 738450152 244 IVQ 246
Cdd:COG4555 232 FVA 234
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
10-226 |
1.49e-68 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 212.46 E-value: 1.49e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD-RSVRQR 88
Cdd:cd03268 1 LKTNDLTKTY-------GKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKnIEALRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 IGYLPENAYYYDYLTGWEFLQLIGGIFQILssvqKKRIPELLDLVGLdrKTAQKKQLRQYSKGMMQRIGIAQALINDPEL 168
Cdd:cd03268 74 IGALIEAPGFYPNLTARENLRLLARLLGIR----KKRIDEVLDVVGL--KDSAKKKVKGFSLGMKQRLGIALALLGNPDL 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 169 VFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELL 226
Cdd:cd03268 148 LILDEPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLI 205
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
9-305 |
8.51e-68 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 213.82 E-value: 8.51e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYRtgfwlNKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIgDRSVRQR 88
Cdd:COG4152 1 MLELKGLTKRFG-----DKTA--VDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPL-DPEDRRR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 IGYLPENAYYYDYLTGWE----FLQLIGgifqiLSSVQ-KKRIPELLDLVGL-DRKtaqKKQLRQYSKGMMQRIGIAQAL 162
Cdd:COG4152 73 IGYLPEERGLYPKMKVGEqlvyLARLKG-----LSKAEaKRRADEWLERLGLgDRA---NKKVEELSKGNQQKVQLIAAL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 163 INDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADVYQ 242
Cdd:COG4152 145 LHDPELLILDEPFSGLDPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFGRNT 224
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 243 VIVQGGGE-EQLQQW--LLGLHWRDNCWHGQLQGE--PDAFLAALSSmDVRLISLNLARASLEEFFID 305
Cdd:COG4152 225 LRLEADGDaGWLRALpgVTVVEEDGDGAELKLEDGadAQELLRALLA-RGPVREFEEVRPSLNEIFIE 291
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
28-239 |
4.99e-66 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 209.55 E-value: 4.99e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 28 KIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILG-----QPigdRSVRQRIGYLPENAYYYDYL 102
Cdd:TIGR01188 5 DFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGydvvrEP---RKVRRSIGIVPQYASVDEDL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 103 TGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLdrKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIG 182
Cdd:TIGR01188 82 TGRENLEMMGRLYGLPKDEAEERAEELLELFEL--GEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRT 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 738450152 183 RYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRAD 239
Cdd:TIGR01188 160 RRAIWDYIRALKEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRLG 216
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
10-234 |
2.05e-62 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 197.21 E-value: 2.05e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRTgfwlnkkIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS--VRQ 87
Cdd:cd03265 1 IEVENLVKKYGD-------FEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPreVRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 88 RIGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLdrKTAQKKQLRQYSKGMMQRIGIAQALINDPE 167
Cdd:cd03265 74 RIGIVFQDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGL--LEAADRLVKTYSGGMRRRLEIARSLVHRPE 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 168 LVFFDEPMSGLDPIGRYQVREIIQSLKQ-QGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:cd03265 152 VLFLDEPTIGLDPQTRAHVWEYIEKLKEeFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
14-229 |
1.40e-60 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 192.41 E-value: 1.40e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRTGfwlnkkiESLKNCTLIVHEGeTFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDR--SVRQRIGY 91
Cdd:cd03264 5 NLTKRYGKK-------RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQpqKLRRRIGY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 92 LPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGL-DRKtaqKKQLRQYSKGMMQRIGIAQALINDPELVF 170
Cdd:cd03264 77 LPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLgDRA---KKKIGSLSGGMRRRVGIAQALVGDPSILI 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 171 FDEPMSGLDPIGRYQVREIIQSLKqQGKTIFFNSHILSDVEQICDRIALLARGELLCVG 229
Cdd:cd03264 154 VDEPTAGLDPEERIRFRNLLSELG-EDRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
10-234 |
1.29e-57 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 185.02 E-value: 1.29e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRTGFWLnkkieSLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI--GDRSVRQ 87
Cdd:cd03263 1 LQIRNLTKTYKKGTKP-----AVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIrtDRKAARQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 88 RIGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKtaQKKQLRQYSKGMMQRIGIAQALINDPE 167
Cdd:cd03263 76 SLGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDK--ANKRARTLSGGMKRKLSLAIALIGGPS 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 738450152 168 LVFFDEPMSGLDPIGRYQVREIIQSLKqQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:cd03263 154 VLLLDEPTSGLDPASRRAIWDLILEVR-KGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQEL 219
|
|
| galliderm_ABC |
TIGR03740 |
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ... |
10-233 |
4.80e-57 |
|
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 183.75 E-value: 4.80e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIgDRSVRQRI 89
Cdd:TIGR03740 1 LETKNLSKRF-------GKQTAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHPW-TRKDLHKI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 90 GYLPENAYYYDYLTGWEFLQliggIFQILSSVQKKRIPELLDLVGLDrkTAQKKQLRQYSKGMMQRIGIAQALINDPELV 169
Cdd:TIGR03740 73 GSLIESPPLYENLTARENLK----VHTTLLGLPDSRIDEVLNIVDLT--NTGKKKAKQFSLGMKQRLGIAIALLNHPKLL 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 738450152 170 FFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQ 233
Cdd:TIGR03740 147 ILDEPTNGLDPIGIQELRELIRSFPEQGITVILSSHILSEVQQLADHIGIISEGVLGYQGKINK 210
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
14-229 |
7.30e-57 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 182.95 E-value: 7.30e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRTgfwLNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILG-----QPigdRSVRQR 88
Cdd:cd03266 6 ALTKRFRD---VKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGfdvvkEP---AEARRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 IGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVG----LDRKTAQkkqlrqYSKGMMQRIGIAQALIN 164
Cdd:cd03266 80 LGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGmeelLDRRVGG------FSTGMRQKVAIARALVH 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738450152 165 DPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVG 229
Cdd:cd03266 154 DPPVLLLDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
32-235 |
1.09e-55 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 180.67 E-value: 1.09e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRsvRQRIGYLPENAYY-YDY-LTGWEFLQ 109
Cdd:COG1121 22 LEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRA--RRRIGYVPQRAEVdWDFpITVRDVVL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 110 L----IGGIFQILSSVQKKRIPELLDLVGL-DRKtaqKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRY 184
Cdd:COG1121 100 MgrygRRGLFRRPSRADREAVDEALERVGLeDLA---DRPIGELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATEE 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 738450152 185 QVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGeLLCVGSLDQIL 235
Cdd:COG1121 177 ALYELLRELRREGKTILVVTHDLGAVREYFDRVLLLNRG-LVAHGPPEEVL 226
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
10-229 |
4.18e-53 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 173.24 E-value: 4.18e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRTgfwlnkkIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDrSVRQRI 89
Cdd:cd03269 1 LEVENVTKRFGR-------VTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDI-AARNRI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 90 GYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKtaQKKQLRQYSKGMMQRIGIAQALINDPELV 169
Cdd:cd03269 73 GYLPEERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEY--ANKRVEELSKGNQQKVQFIAAVIHDPELL 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 170 FFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVG 229
Cdd:cd03269 151 ILDEPFSGLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
32-229 |
1.64e-52 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 171.56 E-value: 1.64e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDrsVRQRIGYLPENAYY-YDY-LTGWEFLq 109
Cdd:cd03235 15 LEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEK--ERKRIGYVPQRRSIdRDFpISVRDVV- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 110 LIG-----GIFQILSSVQKKRIPELLDLVGLDRKtaQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRY 184
Cdd:cd03235 92 LMGlyghkGLFRRLSKADKAKVDEALERVGLSEL--ADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDPKTQE 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 738450152 185 QVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARgELLCVG 229
Cdd:cd03235 170 DIYELLRELRREGMTILVVTHDLGLVLEYFDRVLLLNR-TVVASG 213
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
2-237 |
2.08e-50 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 174.32 E-value: 2.08e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 2 TNTSRQTVLETLNLQKTYRTGFWLNKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIG 81
Cdd:COG1123 253 AAAAAEPLLEVRNLSKRYPVRGKGGVRA--VDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLT 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 82 D------RSVRQRIGYLPENAYY--------YDYLTgwEFLQLIGgifqILSSVQ-KKRIPELLDLVGLDRKTAQKK--Q 144
Cdd:COG1123 331 KlsrrslRELRRRVQMVFQDPYSslnprmtvGDIIA--EPLRLHG----LLSRAErRERVAELLERVGLPPDLADRYphE 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 145 LrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARG 223
Cdd:COG1123 405 L---SGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRElGLTYLFISHDLAVVRYIADRVAVMYDG 481
|
250
....*....|....
gi 738450152 224 ELLCVGSLDQILGR 237
Cdd:COG1123 482 RIVEDGPTEEVFAN 495
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
32-234 |
6.56e-50 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 165.75 E-value: 6.56e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD------RSVRQRIGYLPENAYYYDYLTGW 105
Cdd:cd03261 16 LKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGlseaelYRLRRRMGMLFQSGALFDSLTVF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 106 EFLQL-IGGIFQILSSVQKKRIPELLDLVGLdrKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRY 184
Cdd:cd03261 96 ENVAFpLREHTRLSEEEIREIVLEKLEAVGL--RGAEDLYPAELSGGMKKRVALARALALDPELLLYDEPTAGLDPIASG 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 738450152 185 QVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:cd03261 174 VIDDLIRSLKKElGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
32-235 |
1.27e-48 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 162.46 E-value: 1.27e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD------RSVRQRIGYLPENAYYYDYLTGW 105
Cdd:COG1127 21 LDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGlsekelYELRRRIGMLFQGGALFDSLTVF 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 106 E----FLQLIGGifqiLS-SVQKKRIPELLDLVGLdRKTAQKK--QLrqySKGMMQRIGIAQALINDPELVFFDEPMSGL 178
Cdd:COG1127 101 EnvafPLREHTD----LSeAEIRELVLEKLELVGL-PGAADKMpsEL---SGGMRKRVALARALALDPEILLYDEPTAGL 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 179 DPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL 235
Cdd:COG1127 173 DPITSAVIDELIRELRDElGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELL 230
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
32-239 |
3.86e-48 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 160.96 E-value: 3.86e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS---VRQRIGYL---PENayyydyltgw 105
Cdd:COG1122 17 LDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNlreLRRKVGLVfqnPDD---------- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 106 eflQLIGgifqilSSVQ-----------------KKRIPELLDLVGL----DRKTAQkkqLrqySKGMMQRIGIAQALIN 164
Cdd:COG1122 87 ---QLFA------PTVEedvafgpenlglpreeiRERVEEALELVGLehlaDRPPHE---L---SGGQKQRVAIAGVLAM 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738450152 165 DPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRAD 239
Cdd:COG1122 152 EPEVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDYE 226
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
9-225 |
1.30e-43 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 149.19 E-value: 1.30e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYRTGFWLNKKiesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR 88
Cdd:cd03257 1 LLEVKNLSVSFPTGGGSVKA---LDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 ------IGYLPENAYyydyltgwEFL-------QLIGGIFQILSSV-----QKKRIPELLDLVGLDRKTAQKKQlRQYSK 150
Cdd:cd03257 78 kirrkeIQMVFQDPM--------SSLnprmtigEQIAEPLRIHGKLskkeaRKEAVLLLLVGVGLPEEVLNRYP-HELSG 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 151 GMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:cd03257 149 GQRQRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEElGLTLLFITHDLGVVAKIADRVAVMYAGKI 224
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
26-224 |
1.88e-43 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 148.00 E-value: 1.88e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 26 NKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSV---RQRIGYLPENAyyydyl 102
Cdd:cd03225 11 DGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLkelRRKVGLVFQNP------ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 103 tgweFLQLIG-----------GIFQILSSVQKKRIPELLDLVGLDRKtaQKKQLRQYSKGMMQRIGIAQALINDPELVFF 171
Cdd:cd03225 85 ----DDQFFGptveeevafglENLGLPEEEIEERVEEALELVGLEGL--RDRSPFTLSGGQKQRVAIAGVLAMDPDILLL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 738450152 172 DEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGE 224
Cdd:cd03225 159 DEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
39-223 |
8.08e-43 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 149.57 E-value: 8.08e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 39 VHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS--VRQRIGYLPEnayyYDYL----TGWEFLQLIG 112
Cdd:PRK13537 30 VQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRArhARQRVGVVPQ----FDNLdpdfTVRENLLVFG 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 113 GIFQILSSVQKKRIPELLDLVGLDRKTaqKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQS 192
Cdd:PRK13537 106 RYFGLSAAAARALVPPLLEFAKLENKA--DAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQARHLMWERLRS 183
|
170 180 190
....*....|....*....|....*....|.
gi 738450152 193 LKQQGKTIFFNSHILSDVEQICDRIALLARG 223
Cdd:PRK13537 184 LLARGKTILLTTHFMEEAERLCDRLCVIEEG 214
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
10-225 |
2.45e-42 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 145.33 E-value: 2.45e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRTGfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSV---- 85
Cdd:cd03255 1 IELKNLSKTYGGG---GEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEkela 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 86 ---RQRIGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGL-DRKTAQKKQLrqySKGMMQRIGIAQA 161
Cdd:cd03255 78 afrRRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLgDRLNHYPSEL---SGGQQQRVAIARA 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738450152 162 LINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILsDVEQICDRIALLARGEL 225
Cdd:cd03255 155 LANDPKIILADEPTGNLDSETGKEVMELLRELnKEAGTTIVVVTHDP-ELAEYADRIIELRDGKI 218
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
10-229 |
3.48e-42 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 144.97 E-value: 3.48e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRTGFWLNkkieslkNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR- 88
Cdd:cd03259 1 LELKGLSKTYGSVRALD-------DLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPERRn 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 IGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRkTAQKKQlRQYSKGMMQRIGIAQALINDPEL 168
Cdd:cd03259 74 IGMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEG-LLNRYP-HELSGGQQQRVALARALAREPSL 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 738450152 169 VFFDEPMSGLDPIGRYQVR-EIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVG 229
Cdd:cd03259 152 LLLDEPLSALDAKLREELReELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
14-245 |
7.26e-42 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 147.16 E-value: 7.26e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRT-----GFWLN---------KKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILG-Q 78
Cdd:COG4586 6 NLSKTYRVyekepGLKGAlkglfrreyREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGyV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 79 PigdrsVRQRIgylpENAY------------YYDyLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKTaqKKQLR 146
Cdd:COG4586 86 P-----FKRRK----EFARrigvvfgqrsqlWWD-LPAIDSFRLLKAIYRIPDAEYKKRLDELVELLDLGELL--DTPVR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 147 QYSKGmmQRI--GIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARG 223
Cdd:COG4586 154 QLSLG--QRMrcELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYnRERGTTILLTSHDMDDIEALCDRVIVIDHG 231
|
250 260
....*....|....*....|..
gi 738450152 224 ELLCVGSLDQILGRADVYQVIV 245
Cdd:COG4586 232 RIIYDGSLEELKERFGPYKTIV 253
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
14-237 |
5.61e-41 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 142.82 E-value: 5.61e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRTGFwlnkkiESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSV---RQRIG 90
Cdd:cd03295 5 NVTKRYGGGK------KAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPvelRRKIG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 91 YLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKTAQKKQLRQYSKGMMQRIGIAQALINDPELVF 170
Cdd:cd03295 79 YVIQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLDPAEFADRYPHELSGGQQQRVGVARALAADPPLLL 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 171 FDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGR 237
Cdd:cd03295 159 MDEPFGALDPITRDQLQEEFKRLQQElGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRS 226
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
39-274 |
6.57e-41 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 145.36 E-value: 6.57e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 39 VHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD--RSVRQRIGYLPEnayyYDYL----TGWEFLQLIG 112
Cdd:PRK13536 64 VASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPAraRLARARIGVVPQ----FDNLdlefTVRENLLVFG 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 113 GIFQILSSVQKKRIPELLDLVGLDRKTaqKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQS 192
Cdd:PRK13536 140 RYFGMSTREIEAVIPSLLEFARLESKA--DARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLRS 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 193 LKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADVYQVIVQGGGEEQLQQWLLGLHWRdncwHGQLQ 272
Cdd:PRK13536 218 LLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHALIDEHIGCQVIEIYGGDPHELSSLVKPYAR----RIEVS 293
|
..
gi 738450152 273 GE 274
Cdd:PRK13536 294 GE 295
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
32-243 |
8.30e-41 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 142.49 E-value: 8.30e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVR---QRIGYLPENAYYYDYLTGWEFL 108
Cdd:COG1120 17 LDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRelaRRIAYVPQEPPAPFGLTVRELV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 qLIG-----GIFQILSSVQKKRIPELLDLVGLDRKtaQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPigR 183
Cdd:COG1120 97 -ALGryphlGLFGRPSAEDREAVEEALERTGLEHL--ADRPVDELSGGERQRVLIARALAQEPPLLLLDEPTSHLDL--A 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 184 YQVR--EIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGR---ADVYQV 243
Cdd:COG1120 172 HQLEvlELLRRLaRERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLTPellEEVYGV 237
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
10-243 |
1.35e-40 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 141.53 E-value: 1.35e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRtgfwlNKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR- 88
Cdd:cd03218 1 LRAENLSKRYG-----KRKV--VNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRa 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 ---IGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRktAQKKQLRQYSKGMMQRIGIAQALIND 165
Cdd:cd03218 74 rlgIGYLPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITH--LRKSKASSLSGGERRRVEIARALATN 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 166 PELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADVYQV 243
Cdd:cd03218 152 PKFLLLDEPFAGVDPIAVQDIQKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANELVRKV 229
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
9-237 |
5.24e-40 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 140.02 E-value: 5.24e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYRTGfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD------ 82
Cdd:cd03258 1 MIELKNVSKVFGDT---GGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLlsgkel 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 83 RSVRQRIGYLPENAYYYDYLTGWEFLQL---IGGIFQilsSVQKKRIPELLDLVGL-DRKTAQKKQLrqySKGMMQRIGI 158
Cdd:cd03258 78 RKARRRIGMIFQHFNLLSSRTVFENVALpleIAGVPK---AEIEERVLELLELVGLeDKADAYPAQL---SGGQKQRVGI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 159 AQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGR 237
Cdd:cd03258 152 ARALANNPKVLLCDEATSALDPETTQSILALLRDINRElGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFAN 231
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
10-226 |
6.68e-40 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 139.77 E-value: 6.68e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRT----GFWLN----------KKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALI 75
Cdd:cd03267 1 IEVSNLSKSYRVyskePGLIGslkslfkrkyREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 76 LGQPIGDRSVR--QRIGYL--PENAYYYDyLTGWEFLQLIGGIFQILSSVQKKRIPELLDLvgLDRKTAQKKQLRQYSKG 151
Cdd:cd03267 81 AGLVPWKRRKKflRRIGVVfgQKTQLWWD-LPVIDSFYLLAAIYDLPPARFKKRLDELSEL--LDLEELLDTPVRQLSLG 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 152 MMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGELL 226
Cdd:cd03267 158 QRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYnRERGTTVLLTSHYMKDIEALARRVLVIDKGRLL 233
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
14-224 |
6.93e-40 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 137.38 E-value: 6.93e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS---VRQRIG 90
Cdd:cd00267 4 NLSFRY-------GGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPleeLRRRIG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 91 YLPenayyydyltgweflqliggifqilssvqkkripelldlvgldrktaqkkqlrQYSKGMMQRIGIAQALINDPELVF 170
Cdd:cd00267 77 YVP-----------------------------------------------------QLSGGQRQRVALARALLLNPDLLL 103
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 738450152 171 FDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGE 224
Cdd:cd00267 104 LDEPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
10-224 |
9.95e-40 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 137.32 E-value: 9.95e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD-----RS 84
Cdd:cd03229 1 LELKNVSKRY-------GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDledelPP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 85 VRQRIGYLPENAYYYDYLTGWEFLQLiggifqilssvqkkripelldlvGLdrktaqkkqlrqySKGMMQRIGIAQALIN 164
Cdd:cd03229 74 LRRRIGMVFQDFALFPHLTVLENIAL-----------------------GL-------------SGGQQQRVALARALAM 117
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 738450152 165 DPELVFFDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGE 224
Cdd:cd03229 118 DPDVLLLDEPTSALDPITRREVRALLKSLQAQlGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
32-219 |
1.26e-39 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 138.00 E-value: 1.26e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDR--SVRQRIGYLPENAYYYDYLTGWEFLQ 109
Cdd:COG4133 18 FSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAreDYRRRLAYLGHADGLKPELTVRENLR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 110 LIGGIFQIlsSVQKKRIPELLDLVGLDRktAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREI 189
Cdd:COG4133 98 FWAALYGL--RADREAIDEALEAVGLAG--LADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALDAAGVALLAEL 173
|
170 180 190
....*....|....*....|....*....|
gi 738450152 190 IQSLKQQGKTIFFNSHILSDVEQiCDRIAL 219
Cdd:COG4133 174 IAAHLARGGAVLLTTHQPLELAA-ARVLDL 202
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
7-239 |
9.82e-39 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 143.12 E-value: 9.82e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 7 QTVLETLNLQKTYRTGfwlnkKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPT---SGRALILGQPIGDR 83
Cdd:COG1123 2 TPLLEVRDLSVRYPGG-----DVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLEL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 84 SVRQR---IGYLPENAYYY-DYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKTAQKKQlrQYSKGMMQRIGIA 159
Cdd:COG1123 77 SEALRgrrIGMVFQDPMTQlNPVTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPH--QLSGGQRQRVAIA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 160 QALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRA 238
Cdd:COG1123 155 MALALDPDLLIADEPTTALDVTTQAEILDLLRELQRErGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAP 234
|
.
gi 738450152 239 D 239
Cdd:COG1123 235 Q 235
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
9-225 |
1.11e-38 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 136.66 E-value: 1.11e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYRTGfwlnkkIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD------ 82
Cdd:TIGR02315 1 MLEVENLSKVYPNG------KQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKlrgkkl 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 83 RSVRQRIGYLPENAYYYDYLTGWE--------FLQLIGGIFQILSSVQKKRIPELLDLVGLDRKTAQK-KQLrqySKGMM 153
Cdd:TIGR02315 75 RKLRRRIGMIFQHYNLIERLTVLEnvlhgrlgYKPTWRSLLGRFSEEDKERALSALERVGLADKAYQRaDQL---SGGQQ 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 738450152 154 QRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:TIGR02315 152 QRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRInKEDGITVIINLHQVDLAKKYADRIVGLKAGEI 224
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
14-237 |
3.21e-38 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 138.29 E-value: 3.21e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRTGfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD------RSVRQ 87
Cdd:COG1135 6 NLSKTFPTK---GGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTAlserelRAARR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 88 RIGYlpenayyydyltgweflqliggIFQ---ILSS-------------------VQKKRIPELLDLVGL-DRKTAQKKQ 144
Cdd:COG1135 83 KIGM----------------------IFQhfnLLSSrtvaenvalpleiagvpkaEIRKRVAELLELVGLsDKADAYPSQ 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 145 LrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARG 223
Cdd:COG1135 141 L---SGGQKQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRElGLTIVLITHEMDVVRRICDRVAVLENG 217
|
250
....*....|....
gi 738450152 224 ELLCVGSLDQILGR 237
Cdd:COG1135 218 RIVEQGPVLDVFAN 231
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
10-222 |
4.33e-38 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 134.52 E-value: 4.33e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRTGfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIgdRSVRQRI 89
Cdd:cd03293 1 LEVRNVSKTYGGG---GGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPV--TGPGPDR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 90 GYLPENAYYYDYLTGWE---F-LQLIGgifqILSSVQKKRIPELLDLVGLDRktAQKKQLRQYSKGMMQRIGIAQALIND 165
Cdd:cd03293 76 GYVFQQDALLPWLTVLDnvaLgLELQG----VPKAEARERAEELLELVGLSG--FENAYPHQLSGGMRQRVALARALAVD 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 738450152 166 PELVFFDEPMSGLDPIGRYQVR-EIIQSLKQQGKTIFFNSHilsDVEQ---ICDRIALLAR 222
Cdd:cd03293 150 PDVLLLDEPFSALDALTREQLQeELLDIWRETGKTVLLVTH---DIDEavfLADRVVVLSA 207
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
4-223 |
4.81e-38 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 135.60 E-value: 4.81e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 4 TSRQTVLETLNLQKTYRTGfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIgdR 83
Cdd:COG1116 2 SAAAPALELRGVSKRFPTG---GGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPV--T 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 84 SVRQRIGYLPENAYYYDYLTGWE---F-LQLIGgifqILSSVQKKRIPELLDLVGLDRKtAQK--KQLrqySKGMMQRIG 157
Cdd:COG1116 77 GPGPDRGVVFQEPALLPWLTVLDnvaLgLELRG----VPKAERRERARELLELVGLAGF-EDAypHQL---SGGMRQRVA 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 158 IAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHilsDVE---QICDRIALLARG 223
Cdd:COG1116 149 IARALANDPEVLLMDEPFGALDALTRERLQDELLRLwQETGKTVLFVTH---DVDeavFLADRVVVLSAR 215
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
32-229 |
2.74e-37 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 131.02 E-value: 2.74e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR---IGYLPenayyydyltgwefl 108
Cdd:cd03214 15 LDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELarkIAYVP--------------- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 qliggifQILSSVQkkripeLLDLVGldrktaqkKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPigRYQVR- 187
Cdd:cd03214 80 -------QALELLG------LAHLAD--------RPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDI--AHQIEl 136
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 738450152 188 -EIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGELLCVG 229
Cdd:cd03214 137 lELLRRLaRERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
32-240 |
4.00e-37 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 132.56 E-value: 4.00e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR----IGYLPENAYYYDYLTGWE- 106
Cdd:cd03219 16 LDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIarlgIGRTFQIPRLFPELTVLEn 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 107 -----FLQLIGGIFQILSSVQKKRIPE----LLDLVGLDRKTAQK-KQLrqySKGMMQRIGIAQALINDPELVFFDEPMS 176
Cdd:cd03219 96 vmvaaQARTGSGLLLARARREEREAREraeeLLERVGLADLADRPaGEL---SYGQQRRLEIARALATDPKLLLLDEPAA 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 738450152 177 GLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADV 240
Cdd:cd03219 173 GLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRNNPRV 236
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
7-225 |
3.01e-36 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 129.78 E-value: 3.01e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 7 QTVLETLNLQKTYRTGfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVR 86
Cdd:COG1136 2 SPLLELRNLTKSYGTG---EGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSER 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 87 QR-------IGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGL-DRKTAQKKQLrqySKGMMQRIGI 158
Cdd:COG1136 79 ELarlrrrhIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLgDRLDHRPSQL---SGGQQQRVAI 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 159 AQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILsDVEQICDRIALLARGEL 225
Cdd:COG1136 156 ARALVNRPKLILADEPTGNLDSKTGEEVLELLRELnRELGTTIVMVTHDP-ELAARADRVIRLRDGRI 222
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
32-235 |
3.12e-36 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 130.59 E-value: 3.12e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRAL-ILGQPIGDRSV---RQRIGYL-PE-NAYYYDYLTGW 105
Cdd:COG1119 19 LDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDVrLFGERRGGEDVwelRKRIGLVsPAlQLRFPRDETVL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 106 EFLqLIG-----GIFQILSSVQKKRIPELLDLVGLDRKTaqKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDP 180
Cdd:COG1119 99 DVV-LSGffdsiGLYREPTDEQRERARELLELLGLAHLA--DRPFGTLSQGEQRRVLIARALVKDPELLILDEPTAGLDL 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 181 IGRYQVREIIQSLKQQG-KTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL 235
Cdd:COG1119 176 GARELLLALLDKLAAEGaPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEVL 231
|
|
| LPS_export_lptB |
TIGR04406 |
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ... |
9-243 |
4.96e-36 |
|
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 275199 [Multi-domain] Cd Length: 239 Bit Score: 129.70 E-value: 4.96e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR 88
Cdd:TIGR04406 1 TLVAENLIKSY-------KKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDITHLPMHER 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 ----IGYLPENAYYYDYLTGWEFLQLIGGIFQILS-SVQKKRIPELLDLVGLDRKTAQKKQlrQYSKGMMQRIGIAQALI 163
Cdd:TIGR04406 74 arlgIGYLPQEASIFRKLTVEENIMAVLEIRKDLDrAEREERLEALLEEFQISHLRDNKAM--SLSGGERRRVEIARALA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 164 NDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADVYQV 243
Cdd:TIGR04406 152 TNPKFILLDEPFAGVDPIAVGDIKKIIKHLKERGIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPAEIVANEKVRRV 231
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
10-224 |
9.65e-36 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 129.22 E-value: 9.65e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRTGFwlnkkiESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD------R 83
Cdd:cd03256 1 IEVENLSKTYPNGK------KALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKlkgkalR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 84 SVRQRIGY------LPENAYYYD-YLTG----WEFLQligGIFQILSSVQKKRIPELLDLVGLDRKTAQKKQlrQYSKGM 152
Cdd:cd03256 75 QLRRQIGMifqqfnLIERLSVLEnVLSGrlgrRSTWR---SLFGLFPKEEKQRALAALERVGLLDKAYQRAD--QLSGGQ 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 738450152 153 MQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGE 224
Cdd:cd03256 150 QQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRInREEGITVIVSLHQVDLAREYADRIVGLKDGR 222
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
9-243 |
1.32e-35 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 128.61 E-value: 1.32e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR 88
Cdd:COG1137 3 TLEAENLVKSY-------GKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHKR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 ----IGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKtaqKKQL-RQYSKGMMQRIGIAQALI 163
Cdd:COG1137 76 arlgIGYLPQEASIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHL---RKSKaYSLSGGERRRVEIARALA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 164 NDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADVYQV 243
Cdd:COG1137 153 TNPKFILLDEPFAGVDPIAVADIQKIIRHLKERGIGVLITDHNVRETLGICDRAYIISEGKVLAEGTPEEILNNPLVRKV 232
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
32-174 |
2.89e-35 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 125.07 E-value: 2.89e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPENAYYYDYLTGWEFL 108
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDderKSLRKEIGYVFQDPQLFPRLTVRENL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 109 QLIGGIFQILSSVQKKRIPELLDLVGL--DRKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEP 174
Cdd:pfam00005 81 RLGLLLKGLSKREKDARAEEALEKLGLgdLADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEP 148
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
13-235 |
7.75e-35 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 126.73 E-value: 7.75e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 13 LNLQKTYRTGFWlnkkieSLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGqpigdrsvrqRI--- 89
Cdd:COG1134 29 LRRRRTRREEFW------ALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNG----------RVsal 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 90 -----GYLPEnayyydyLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKTAQKkqLRQYSKGMMQRIGIAQALIN 164
Cdd:COG1134 93 lelgaGFHPE-------LTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQP--VKTYSSGMRARLAFAVATAV 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 738450152 165 DPELVFFDEPMSGLDPigRYQ--VREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL 235
Cdd:COG1134 164 DPDILLVDEVLAVGDA--AFQkkCLARIRELRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVI 234
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
8-225 |
3.89e-34 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 125.17 E-value: 3.89e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 8 TVLETLNLQKTYRTGFwlnkkiESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD----- 82
Cdd:COG3638 1 PMLELRNLSKRYPGGT------PALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTAlrgra 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 83 -RSVRQRIGYLP------------ENAyyydyLTG----WEFLQligGIFQILSSVQKKRIPELLDLVGLDRKTAQK-KQ 144
Cdd:COG3638 75 lRRLRRRIGMIFqqfnlvprlsvlTNV-----LAGrlgrTSTWR---SLLGLFPPEDRERALEALERVGLADKAYQRaDQ 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 145 LrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARG 223
Cdd:COG3638 147 L---SGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIaREDGITVVVNLHQVDLARRYADRIIGLRDG 223
|
..
gi 738450152 224 EL 225
Cdd:COG3638 224 RV 225
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
14-239 |
7.06e-34 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 125.26 E-value: 7.06e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRTGFWLNKKieSLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD------RSVRQ 87
Cdd:TIGR04521 5 NVSYIYQPGTPFEKK--ALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAkkkkklKDLRK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 88 RIGYL---PENayyydyltgweflQLiggiFQ--ILSSVQ-------------KKRIPELLDLVGLDRKTAQKK--QLrq 147
Cdd:TIGR04521 83 KVGLVfqfPEH-------------QL----FEetVYKDIAfgpknlglseeeaEERVKEALELVGLDEEYLERSpfEL-- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 148 ySKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGELL 226
Cdd:TIGR04521 144 -SGGQMRRVAIAGVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLhKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIV 222
|
250
....*....|...
gi 738450152 227 CVGSLDQILGRAD 239
Cdd:TIGR04521 223 LDGTPREVFSDVD 235
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
9-237 |
1.70e-33 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 125.17 E-value: 1.70e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYRTGfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRP---TSGRALILGQPIGD--- 82
Cdd:COG0444 1 LLEVRNLKVYFPTR---RGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLLKlse 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 83 ---RSVR-QRIGYLPENAYyyDYLT-----GW---EFLQliggIFQILSSVQ-KKRIPELLDLVGLDRktaQKKQLRQY- 148
Cdd:COG0444 78 kelRKIRgREIQMIFQDPM--TSLNpvmtvGDqiaEPLR----IHGGLSKAEaRERAIELLERVGLPD---PERRLDRYp 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 149 ---SKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGE 224
Cdd:COG0444 149 helSGGMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRElGLAILFITHDLGVVAEIADRVAVMYAGR 228
|
250
....*....|...
gi 738450152 225 LLCVGSLDQILGR 237
Cdd:COG0444 229 IVEEGPVEELFEN 241
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
23-225 |
2.83e-33 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 121.60 E-value: 2.83e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 23 FWLNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQRIGYLPENAYYYDYl 102
Cdd:cd03226 7 FSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKERRKSIGYVMQDVDYQLF- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 103 TGWEFLQLIGGIFQILSSVQKKRipELLDLVGLDRKtaQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIG 182
Cdd:cd03226 86 TDSVREELLLGLKELDAGNEQAE--TVLKDLDLYAL--KERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKN 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 738450152 183 RYQVREIIQSLKQQGKTIFFNSHilsDVE---QICDRIALLARGEL 225
Cdd:cd03226 162 MERVGELIRELAAQGKAVIVITH---DYEflaKVCDRVLLLANGAI 204
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
3-218 |
3.15e-33 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 124.84 E-value: 3.15e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 3 NTSRQTVLETLNLQKTY--RTGFwLNKKIESLK---NCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILG 77
Cdd:COG4608 1 AAMAEPLLEVRDLKKHFpvRGGL-FGRTVGVVKavdGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 78 QPIGD------RSVRQRIgylpenayyydyltgweflQLIggiFQ--------------ILSSV-----------QKKRI 126
Cdd:COG4608 80 QDITGlsgrelRPLRRRM-------------------QMV---FQdpyaslnprmtvgdIIAEPlrihglaskaeRRERV 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 127 PELLDLVGLDRKTAQkkqlR---QYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFF 202
Cdd:COG4608 138 AELLELVGLRPEHAD----RyphEFSGGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDElGLTYLF 213
|
250
....*....|....*.
gi 738450152 203 NSHILSDVEQICDRIA 218
Cdd:COG4608 214 ISHDLSVVRHISDRVA 229
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
32-239 |
7.84e-33 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 121.68 E-value: 7.84e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR-----------IGYLPEnayyyd 100
Cdd:COG0411 20 VDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIarlgiartfqnPRLFPE------ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 101 yLTGWEFLQL----------IGGIFQILSSVQK-----KRIPELLDLVGLDRKTAQK-KQLrqySKGMMQRIGIAQALIN 164
Cdd:COG0411 94 -LTVLENVLVaaharlgrglLAALLRLPRARREerearERAEELLERVGLADRADEPaGNL---SYGQQRRLEIARALAT 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 165 DPELVFFDEPMSGLDPIGRYQVREIIQSLKQ-QGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIlgRAD 239
Cdd:COG0411 170 EPKLLLLDEPAAGLNPEETEELAELIRRLRDeRGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTPAEV--RAD 243
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
32-235 |
8.53e-33 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 121.98 E-value: 8.53e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD------RSVR--------QRIGYLP---- 93
Cdd:cd03294 40 VNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAmsrkelRELRrkkismvfQSFALLPhrtv 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 94 -ENAYYydyltGWEfLQLIGgifqilSSVQKKRIPELLDLVGL-DRKTAQKKQLrqySKGMMQRIGIAQALINDPELVFF 171
Cdd:cd03294 120 lENVAF-----GLE-VQGVP------RAEREERAAEALELVGLeGWEHKYPDEL---SGGMQQRVGLARALAVDPDILLM 184
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738450152 172 DEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL 235
Cdd:cd03294 185 DEAFSALDPLIRREMQDELLRLqAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEIL 249
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
14-225 |
1.11e-32 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 120.54 E-value: 1.11e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRTGfwlnkkIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS------VRQ 87
Cdd:COG2884 6 NVSKRYPGG------REALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKrreipyLRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 88 RIGY-------LPEnayyydyLTGWE---F-LQLIGgifqILSSVQKKRIPELLDLVGLDRKtaQKKQLRQYSKGMMQRI 156
Cdd:COG2884 80 RIGVvfqdfrlLPD-------RTVYEnvaLpLRVTG----KSRKEIRRRVREVLDLVGLSDK--AKALPHELSGGEQQRV 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 157 GIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:COG2884 147 AIARALVNRPELLLADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLELVDRMPKRVLELEDGRL 215
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
26-224 |
1.48e-32 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 118.64 E-value: 1.48e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 26 NKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPENAYYYDyl 102
Cdd:cd03228 12 GRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDldlESLRKNIAYVPQDPFLFS-- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 103 tgweflqliGGIFQ-ILSSVQKkripelldlvgldrktaqkkqlrqyskgmmQRIGIAQALINDPELVFFDEPMSGLDPI 181
Cdd:cd03228 90 ---------GTIREnILSGGQR------------------------------QRIAIARALLRDPPILILDEATSALDPE 130
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 738450152 182 GRYQVREIIQSLKqQGKTIFFNSHILSDVEQiCDRIALLARGE 224
Cdd:cd03228 131 TEALILEALRALA-KGKTVIVIAHRLSTIRD-ADRIIVLDDGR 171
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
32-275 |
1.91e-32 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 122.90 E-value: 1.91e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR-IGYLPENayyYD---YLTGWE- 106
Cdd:COG3842 21 LDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRnVGMVFQD---YAlfpHLTVAEn 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 107 --F-LQLIGgifqiLS-SVQKKRIPELLDLVGL----DRKTAQkkqLrqySKGMMQRIGIAQALINDPELVFFDEPMSGL 178
Cdd:COG3842 98 vaFgLRMRG-----VPkAEIRARVAELLELVGLeglaDRYPHQ---L---SGGQQQRVALARALAPEPRVLLLDEPLSAL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 179 DPIGRYQVR-EIIQSLKQQGKTIFFNSHilsDVEQ---ICDRIALLARGELLCVGSLDQI------------LGRADVYQ 242
Cdd:COG3842 167 DAKLREEMReELRRLQRELGITFIYVTH---DQEEalaLADRIAVMNDGRIEQVGTPEEIyerpatrfvadfIGEANLLP 243
|
250 260 270
....*....|....*....|....*....|...
gi 738450152 243 VIVQGGGEEQLQqwLLGLHWRDNCWHGQLQGEP 275
Cdd:COG3842 244 GTVLGDEGGGVR--TGGRTLEVPADAGLAAGGP 274
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
28-235 |
3.73e-31 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 116.38 E-value: 3.73e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 28 KIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR----IGYLPENAYYYDYLT 103
Cdd:cd03224 12 KSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERaragIGYVPEGRRIFPELT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 104 GWEFLQLigGIFQILSSVQKKRIPELLDLvgLDRKTAQKKQL-RQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIG 182
Cdd:cd03224 92 VEENLLL--GAYARRRAKRKARLERVYEL--FPRLKERRKQLaGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPKI 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 183 RYQVREIIQSLKQQGKTIffnshILsdVEQ-------ICDRIALLARGELLCVGSLDQIL 235
Cdd:cd03224 168 VEEIFEAIRELRDEGVTI-----LL--VEQnarfaleIADRAYVLERGRVVLEGTAAELL 220
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
27-225 |
3.90e-31 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 116.48 E-value: 3.90e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 27 KKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQP-----IGdrsvrqrIGYLPEnayyydy 101
Cdd:cd03220 33 GEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRVssllgLG-------GGFNPE------- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 102 LTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRktAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPI 181
Cdd:cd03220 99 LTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGD--FIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAA 176
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 738450152 182 GRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:cd03220 177 FQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKI 220
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
10-225 |
5.44e-31 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 114.06 E-value: 5.44e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRTgfwlnkkIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVR--Q 87
Cdd:cd03216 1 LELRGITKRFGG-------VKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRdaR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 88 RIGylpenayyydyltgweflqlIGGIFQIlssvqkkripelldlvgldrktaqkkqlrqySKGMMQRIGIAQALINDPE 167
Cdd:cd03216 74 RAG--------------------IAMVYQL-------------------------------SVGERQMVEIARALARNAR 102
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 168 LVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:cd03216 103 LLILDEPTAALTPAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGRV 160
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
32-247 |
6.05e-31 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 122.64 E-value: 6.05e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPENAY-----YYDYLT 103
Cdd:COG2274 491 LDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQidpASLRRQIGVVLQDVFlfsgtIRENIT 570
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 104 GWEflqliggifqilSSVQKKRIPELLDLVGLDRKTAQ-KKQL--------RQYSKGMMQRIGIAQALINDPELVFFDEP 174
Cdd:COG2274 571 LGD------------PDATDEEIIEAARLAGLHDFIEAlPMGYdtvvgeggSNLSGGQRQRLAIARALLRNPRILILDEA 638
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738450152 175 MSGLDPIGRyqvREIIQSLKQ--QGKTIFFNSHILSDVeQICDRIALLARGELLCVGSLDQILGRADVYQVIVQG 247
Cdd:COG2274 639 TSALDAETE---AIILENLRRllKGRTVIIIAHRLSTI-RLADRIIVLDKGRIVEDGTHEELLARKGLYAELVQQ 709
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
14-251 |
6.50e-31 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 116.53 E-value: 6.50e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRtgfwlNKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQ-----PIGDRSvRQR 88
Cdd:PRK10895 8 NLAKAYK-----GRRV--VEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEdisllPLHARA-RRG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 IGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKK-RIPELLDLVGLDRKTAQKKQlrQYSKGMMQRIGIAQALINDPE 167
Cdd:PRK10895 80 IGYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREdRANELMEEFHIEHLRDSMGQ--SLSGGERRRVEIARALAANPK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 168 LVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADVYQVIVqg 247
Cdd:PRK10895 158 FILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRVYL-- 235
|
....
gi 738450152 248 gGEE 251
Cdd:PRK10895 236 -GED 238
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
28-234 |
9.92e-31 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 115.36 E-value: 9.92e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 28 KIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTL-----LGIVRPTSGRALILGQPIGDR-----SVRQRIGYL----- 92
Cdd:cd03260 12 DKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLnrlndLIPGAPDEGEVLLDGKDIYDLdvdvlELRRRVGMVfqkpn 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 93 PENAYYYDYLtgwEFLQLIGGIfqILSSVQKKRIPELLDLVGLDRKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFD 172
Cdd:cd03260 92 PFPGSIYDNV---AYGLRLHGI--KLKEELDERVEEALRKAALWDEVKDRLHALGLSGGQQQRLCLARALANEPEVLLLD 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 738450152 173 EPMSGLDPIGRYQVREIIQSLKQQgKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:cd03260 167 EPTSALDPISTAKIEELIAELKKE-YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
32-234 |
3.87e-30 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 113.87 E-value: 3.87e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR-IGYLPENAYYYDYLTGWEFLQL 110
Cdd:cd03300 16 LDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRpVNTVFQNYALFPHLTVFENIAF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 111 IGGIFQILSSVQKKRIPELLDLVGLDrkTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREII 190
Cdd:cd03300 96 GLRLKKLPKAEIKERVAEALDLVQLE--GYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALDLKLRKDMQLEL 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 738450152 191 QSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:cd03300 174 KRLQKElGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEI 218
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
28-240 |
4.31e-30 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 113.92 E-value: 4.31e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 28 KIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS----VRQRIGYLPENAYYYDYLT 103
Cdd:COG0410 15 GIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPphriARLGIGYVPEGRRIFPSLT 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 104 GWEFLQLiGGIFQILSSVQKKRIPELLDL--VGLDRKTAQKKQLrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDPI 181
Cdd:COG0410 95 VEENLLL-GAYARRDRAEVRADLERVYELfpRLKERRRQRAGTL---SGGEQQMLAIGRALMSRPKLLLLDEPSLGLAPL 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 182 GRYQVREIIQSLKQQGKTIFFnshilsdVEQ-------ICDRIALLARGELLCVGSLDQILGRADV 240
Cdd:COG0410 171 IVEEIFEIIRRLNREGVTILL-------VEQnarfaleIADRAYVLERGRIVLEGTAAELLADPEV 229
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
14-229 |
5.39e-30 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 112.64 E-value: 5.39e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTyRTGFWLNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLG--IVRPTSGRALILGQPIGDRSVRQRIGY 91
Cdd:cd03213 8 NLTVT-VKSSPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPLDKRSFRKIIGY 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 92 LPENAYYYDYLTGWEFLQLiggifqilssvqkkripelldlvgldrkTAQkkqLRQYSKGMMQRIGIAQALINDPELVFF 171
Cdd:cd03213 87 VPQDDILHPTLTVRETLMF----------------------------AAK---LRGLSGGERKRVSIALELVSNPSLLFL 135
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 172 DEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILS-DVEQICDRIALLARGELLCVG 229
Cdd:cd03213 136 DEPTSGLDSSSALQVMSLLRRLADTGRTIICSIHQPSsEIFELFDKLLLLSQGRVIYFG 194
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
31-243 |
1.03e-29 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 113.20 E-value: 1.03e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 31 SLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS-VRQRIGYLPENAYYYDYLTGWEFLQ 109
Cdd:cd03299 14 KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPpEKRDISYVPQNYALFPHMTVYKNIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 110 LiGGIFQILSSVQ-KKRIPELLDLVG----LDRKTaqkkqlRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRY 184
Cdd:cd03299 94 Y-GLKKRKVDKKEiERKVLEIAEMLGidhlLNRKP------ETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKE 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 185 QVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADVYQV 243
Cdd:cd03299 167 KLREELKKIrKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFV 226
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
10-225 |
1.26e-29 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 112.24 E-value: 1.26e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS----- 84
Cdd:cd03262 1 IEIKNLHKSF-------GDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKknine 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 85 VRQRIGYLPENAYYYDYLTgweFLQLIggifqILSSVQKKRIP---------ELLDLVGL-DRKTAQKKQLrqySKGMMQ 154
Cdd:cd03262 74 LRQKVGMVFQQFNLFPHLT---VLENI-----TLAPIKVKGMSkaeaeeralELLEKVGLaDKADAYPAQL---SGGQQQ 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 738450152 155 RIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:cd03262 143 RVAIARALAMNPKVMLFDEPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
30-211 |
1.42e-29 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 111.36 E-value: 1.42e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 30 ESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIG-DRS----VRQRIGYLPENA----YYYD 100
Cdd:TIGR01166 6 EVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPLDySRKglleRRQRVGLVFQDPddqlFAAD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 101 YLTGWEFLQLIGGifqiLSSVQ-KKRIPELLDLVGLDRktAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLD 179
Cdd:TIGR01166 86 VDQDVAFGPLNLG----LSEAEvERRVREALTAVGASG--LRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEPTAGLD 159
|
170 180 190
....*....|....*....|....*....|..
gi 738450152 180 PIGRYQVREIIQSLKQQGKTIFFNSHilsDVE 211
Cdd:TIGR01166 160 PAGREQMLAILRRLRAEGMTVVISTH---DVD 188
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
10-225 |
1.55e-29 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 112.12 E-value: 1.55e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRTGfwlnkkIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSV- 85
Cdd:cd03292 1 IEFINVTKTYPNG------TAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDlrgRAIp 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 86 --RQRIGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGL-DRKTAQKKQLrqySKGMMQRIGIAQAL 162
Cdd:cd03292 75 ylRRKIGVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLsHKHRALPAEL---SGGEQQRVAIARAI 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 738450152 163 INDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:cd03292 152 VNSPTILIADEPTGNLDPDTTWEIMNLLKKINKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
14-234 |
4.46e-29 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 114.01 E-value: 4.46e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR-IGYL 92
Cdd:COG3839 8 NVSKSY-------GGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKDRnIAMV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 93 PENayY--YDYLTGWE---F-LQLIGgifqILSSVQKKRIPELLDLVG----LDRKTaqkKQLrqySKGMMQRIGIAQAL 162
Cdd:COG3839 81 FQS--YalYPHMTVYEniaFpLKLRK----VPKAEIDRRVREAAELLGledlLDRKP---KQL---SGGQRQRVALGRAL 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 163 INDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHilsdvEQI-----CDRIALLARGELLCVGSLDQI 234
Cdd:COG3839 149 VREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRlGTTTIYVTH-----DQVeamtlADRIAVMNDGRIQQVGTPEEL 221
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
9-237 |
1.48e-28 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 110.08 E-value: 1.48e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD-----R 83
Cdd:COG1126 1 MIEIENLHKSF-------GDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDskkdiN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 84 SVRQRIGYlpenayyydyltgweflqliggIFQ--------------ILSSVQKKRIP---------ELLDLVGL-DRKT 139
Cdd:COG1126 74 KLRRKVGM----------------------VFQqfnlfphltvlenvTLAPIKVKKMSkaeaeeramELLERVGLaDKAD 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 140 AQKKQLrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDP--IGryQVREIIQSLKQQGKTIFFNSHILSDVEQICDRI 217
Cdd:COG1126 132 AYPAQL---SGGQQQRVAIARALAMEPKVMLFDEPTSALDPelVG--EVLDVMRDLAKEGMTMVVVTHEMGFAREVADRV 206
|
250 260
....*....|....*....|
gi 738450152 218 ALLARGELLCVGSLDQILGR 237
Cdd:COG1126 207 VFMDGGRIVEEGPPEEFFEN 226
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
32-225 |
2.00e-28 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 107.69 E-value: 2.00e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPENAyyydyltgwefl 108
Cdd:cd03246 18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQwdpNELGDHVGYLPQDD------------ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 QLIGG-IFQ-ILSSvqkkripelldlvgldrktaqkkqlrqyskGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQV 186
Cdd:cd03246 86 ELFSGsIAEnILSG------------------------------GQRQRLGLARALYGNPRILVLDEPNSHLDVEGERAL 135
|
170 180 190
....*....|....*....|....*....|....*....
gi 738450152 187 REIIQSLKQQGKTIFFNSHILSDVEQiCDRIALLARGEL 225
Cdd:cd03246 136 NQAIAALKAAGATRIVIAHRPETLAS-ADRILVLEDGRV 173
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
14-225 |
2.53e-28 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 111.82 E-value: 2.53e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRTGfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQrigylp 93
Cdd:PRK11153 6 NISKVFPQG---GRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKE------ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 94 enayyydyLTgwEFLQLIGGIFQ---ILSSVQ-------------------KKRIPELLDLVGL-DRKTAQKKQLrqySK 150
Cdd:PRK11153 77 --------LR--KARRQIGMIFQhfnLLSSRTvfdnvalplelagtpkaeiKARVTELLELVGLsDKADRYPAQL---SG 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 151 GMMQRIGIAQALINDPELVFFDEPMSGLDPigrYQVREIIQSLKQ----QGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK11153 144 GQKQRVAIARALASNPKVLLCDEATSALDP---ATTRSILELLKDinreLGLTIVLITHEMDVVKRICDRVAVIDAGRL 219
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
10-235 |
3.64e-28 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 111.39 E-value: 3.64e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRtGFWLnkkiesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIG-DRSVRQR 88
Cdd:COG1118 3 IEVRNISKRFG-SFTL------LDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFtNLPPRER 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 -IGYLPENayyYD---YLTgweflqliggIFQ----------ILSSVQKKRIPELLDLVGL----DRKTAQkkqLrqySK 150
Cdd:COG1118 76 rVGFVFQH---YAlfpHMT----------VAEniafglrvrpPSKAEIRARVEELLELVQLeglaDRYPSQ---L---SG 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 151 GMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVR-EIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVG 229
Cdd:COG1118 137 GQRQRVALARALAVEPEVLLLDEPFGALDAKVRKELRrWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVG 216
|
....*.
gi 738450152 230 SLDQIL 235
Cdd:COG1118 217 TPDEVY 222
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
39-230 |
3.90e-28 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 114.45 E-value: 3.90e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 39 VHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI--GDRSVRQRIGYLPENAYYYDYLTGWEFLQLIGGIFQ 116
Cdd:NF033858 289 IRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVdaGDIATRRRVGYMSQAFSLYGELTVRQNLELHARLFH 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 117 ILSSVQKKRIPELLDLVGL-DRKTAQKKQLrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-K 194
Cdd:NF033858 369 LPAAEIAARVAEMLERFDLaDVADALPDSL---PLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIELsR 445
|
170 180 190
....*....|....*....|....*....|....*.
gi 738450152 195 QQGKTIFFNSHILSDVEQiCDRIALLARGELLCVGS 230
Cdd:NF033858 446 EDGVTIFISTHFMNEAER-CDRISLMHAGRVLASDT 480
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
39-234 |
4.83e-28 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 114.73 E-value: 4.83e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 39 VHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI--GDRSVRQRIGYLPENAYYYDYLTGWEFLQLiggiFQ 116
Cdd:TIGR01257 1962 VRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSIltNISDVHQNMGYCPQFDAIDDLLTGREHLYL----YA 2037
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 117 ILSSVQKKRIPELLD--LVGLDRKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLK 194
Cdd:TIGR01257 2038 RLRGVPAEEIEKVANwsIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSII 2117
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 738450152 195 QQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:TIGR01257 2118 REGRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHL 2157
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
21-261 |
7.14e-28 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 108.94 E-value: 7.14e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 21 TGFWLNKKIES-LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI-----GDRSVRQRIGYL-- 92
Cdd:PRK13638 5 SDLWFRYQDEPvLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLdyskrGLLALRQQVATVfq 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 93 -PENAYYY-DYLTGWEF-LQLIGgifqILSSVQKKRIPELLDLVglDRKTAQKKQLRQYSKGMMQRIGIAQALINDPELV 169
Cdd:PRK13638 85 dPEQQIFYtDIDSDIAFsLRNLG----VPEAEITRRVDEALTLV--DAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 170 FFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRAdvyQVIVQGGg 249
Cdd:PRK13638 159 LLDEPTAGLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFACT---EAMEQAG- 234
|
250
....*....|..
gi 738450152 250 eeQLQQWLLGLH 261
Cdd:PRK13638 235 --LTQPWLVKLH 244
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
32-229 |
9.35e-28 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 107.34 E-value: 9.35e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR-IGYLPENAYYYDYLTGWEFLQL 110
Cdd:cd03301 16 LDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKDRdIAMVFQNYALYPHMTVYDNIAF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 111 IGGIFQILSSVQKKRIPELLDLVG----LDRKTaqkkqlRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQV 186
Cdd:cd03301 96 GLKLRKVPKDEIDERVREVAELLQiehlLDRKP------KQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAKLRVQM 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 738450152 187 R-EIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVG 229
Cdd:cd03301 170 RaELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
41-226 |
1.74e-27 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 106.61 E-value: 1.74e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 41 EGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSV-------RQRIGYLPENAYYYDYLTGWEflQLIGG 113
Cdd:cd03297 22 NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKkinlppqQRKIGLVFQQYALFPHLNVRE--NLAFG 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 114 IFQILSSVQKKRIPELLDLVGLDRktAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL 193
Cdd:cd03297 100 LKRKRNREDRISVDELLDLLGLDH--LLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPELKQI 177
|
170 180 190
....*....|....*....|....*....|....
gi 738450152 194 KQQ-GKTIFFNSHILSDVEQICDRIALLARGELL 226
Cdd:cd03297 178 KKNlNIPVIFVTHDLSEAEYLADRIVVMEDGRLQ 211
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
9-240 |
2.01e-27 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 107.86 E-value: 2.01e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYRTGfwlnkkIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIG-DRS--- 84
Cdd:PRK13639 1 ILETRDLKYSYPDG------TEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKyDKKsll 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 85 -VRQRIGYLPENAyyYDYLTGWEFLQLI--GGIFQILSSVQ-KKRIPELLDLVGLDrkTAQKKQLRQYSKGMMQRIGIAQ 160
Cdd:PRK13639 75 eVRKTVGIVFQNP--DDQLFAPTVEEDVafGPLNLGLSKEEvEKRVKEALKAVGME--GFENKPPHHLSGGQKKRVAIAG 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 161 ALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADV 240
Cdd:PRK13639 151 ILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDIET 230
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
29-236 |
2.22e-27 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 111.43 E-value: 2.22e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 29 IESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALI-LGQ---------PIGDRSVRQRIGYLPENAYY 98
Cdd:TIGR03269 297 VKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVrVGDewvdmtkpgPDGRGRAKRYIGILHQEYDL 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 99 YDYLTGWEFL-QLIGgiFQILSSVQKKRIPELLDLVGLDRKTAQK---KQLRQYSKGMMQRIGIAQALINDPELVFFDEP 174
Cdd:TIGR03269 377 YPHRTVLDNLtEAIG--LELPDELARMKAVITLKMVGFDEEKAEEildKYPDELSEGERHRVALAQVLIKEPRIVILDEP 454
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 738450152 175 MSGLDPIGRYQVRE-IIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILG 236
Cdd:TIGR03269 455 TGTMDPITKVDVTHsILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEIVE 517
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
32-232 |
2.63e-27 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 110.88 E-value: 2.63e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVR--QRIGylpenayyydyltgweflq 109
Cdd:COG1129 20 LDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRdaQAAG------------------- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 110 lIGGIFQILS-----SV--------------------QKKRIPELLDLVGLDRKTAQKkqLRQYSKGMMQRIGIAQALIN 164
Cdd:COG1129 81 -IAIIHQELNlvpnlSVaeniflgreprrgglidwraMRRRARELLARLGLDIDPDTP--VGDLSVAQQQLVEIARALSR 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 165 DPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELlcVGSLD 232
Cdd:COG1129 158 DARVLILDEPTASLTEREVERLFRIIRRLKAQGVAIIYISHRLDEVFEIADRVTVLRDGRL--VGTGP 223
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
32-235 |
4.28e-27 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 111.00 E-value: 4.28e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPENAYyydyltgwefl 108
Cdd:COG4988 353 LDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDldpASWRRQIAWVPQNPY----------- 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 qliggIFQ------IL---SSVQKKRIPELLDLVGLDRKTAQKKQ-L--------RQYSKGMMQRIGIAQALINDPELVF 170
Cdd:COG4988 422 -----LFAgtirenLRlgrPDASDEELEAALEAAGLDEFVAALPDgLdtplgeggRGLSGGQAQRLALARALLRDAPLLL 496
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738450152 171 FDEPMSGLDPIGRYQVREIIQSLKqQGKTIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQIL 235
Cdd:COG4988 497 LDEPTAHLDAETEAEILQALRRLA-KGRTVILITHRLALLAQ-ADRILVLDDGRIVEQGTHEELL 559
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
31-234 |
7.46e-27 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 105.50 E-value: 7.46e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 31 SLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR-IGYLPENAYYYDYLTGWE--- 106
Cdd:cd03296 17 ALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQERnVGFVFQHYALFRHMTVFDnva 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 107 FLQLIGGIFQILSSVQ-KKRIPELLDLVGLDrkTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQ 185
Cdd:cd03296 97 FGLRVKPRSERPPEAEiRAKVHELLKLVQLD--WLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDAKVRKE 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 738450152 186 VREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:cd03296 175 LRRWLRRLHDElHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEV 224
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
32-242 |
8.89e-27 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 109.86 E-value: 8.89e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPENAYyydyltgwefl 108
Cdd:COG4987 351 LDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDldeDDLRRRIAVVPQRPH----------- 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 qliggIFQilSSV-----------QKKRIPELLDLVGLDR-KTAQKKQL--------RQYSKGMMQRIGIAQALINDPEL 168
Cdd:COG4987 420 -----LFD--TTLrenlrlarpdaTDEELWAALERVGLGDwLAALPDGLdtwlgeggRRLSGGERRRLALARALLRDAPI 492
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 169 VFFDEPMSGLDPIgryQVREIIQSLKQ--QGKTIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQILGRADVYQ 242
Cdd:COG4987 493 LLLDEPTEGLDAA---TEQALLADLLEalAGRTVLLITHRLAGLER-MDRILVLEDGRIVEQGTHEELLAQNGRYR 564
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
32-225 |
9.11e-27 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 104.51 E-value: 9.11e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSV---RQRIGYLPENAYYYDYLTGwEFL 108
Cdd:COG4619 16 LSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPpewRRQVAYVPQEPALWGGTVR-DNL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 QLIGGIFQIlsSVQKKRIPELLDLVGLDRKTAQKkQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVRE 188
Cdd:COG4619 95 PFPFQLRER--KFDRERALELLERLGLPPDILDK-PVERLSGGERQRLALIRALLLQPDVLLLDEPTSALDPENTRRVEE 171
|
170 180 190
....*....|....*....|....*....|....*...
gi 738450152 189 IIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:COG4619 172 LLREYlAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
14-244 |
1.64e-26 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 105.90 E-value: 1.64e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRTGFWLNKKieSLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSV-----RQR 88
Cdd:PRK13637 7 NLTHIYMEGTPFEKK--ALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVklsdiRKK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 IGY--------LPENAYYYDYLTGWEFLQLIGGifQIlssvqKKRIPELLDLVGLDRKTAQKKQLRQYSKGMMQRIGIAQ 160
Cdd:PRK13637 85 VGLvfqypeyqLFEETIEKDIAFGPINLGLSEE--EI-----ENRVKRAMNIVGLDYEDYKDKSPFELSGGQKRRVAIAG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 161 ALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGK-TIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRAD 239
Cdd:PRK13637 158 VVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNmTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFKEVE 237
|
....*
gi 738450152 240 VYQVI 244
Cdd:PRK13637 238 TLESI 242
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
8-225 |
2.92e-26 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 104.77 E-value: 2.92e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 8 TVLETLNLQKTYRTGFWLNKK--IESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSV 85
Cdd:PRK10419 2 TLLNVSGLSHHYAHGGLSGKHqhQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 86 RQRIGYLPE-NAYYYDYLTGWEFLQLIGGIF-----QILS---SVQKKRIPELLDLVGLDRKTAQKKQlRQYSKGMMQRI 156
Cdd:PRK10419 82 AQRKAFRRDiQMVFQDSISAVNPRKTVREIIreplrHLLSldkAERLARASEMLRAVDLDDSVLDKRP-PQLSGGQLQRV 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 157 GIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIF-FNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK10419 161 CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTAClFITHDLRLVERFCQRVMVMDNGQI 230
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
26-229 |
3.26e-26 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 103.50 E-value: 3.26e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 26 NKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRP---TSGRALILGQPIGDRSVRQRIGYLPENAYYYDYL 102
Cdd:cd03234 17 NKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGggtTSGQILFNGQPRKPDQFQKCVAYVRQDDILLPGL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 103 TGWEFLQLIGGIfqILSSVQKKRIPELLDLVGLDRKTAQK----KQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGL 178
Cdd:cd03234 97 TVRETLTYTAIL--RLPRKSSDAIRKKRVEDVLLRDLALTriggNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGL 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 738450152 179 DPIGRYQVREIIQSLKQQGKTIFFNSHI-LSDVEQICDRIALLARGELLCVG 229
Cdd:cd03234 175 DSFTALNLVSTLSQLARRNRIVILTIHQpRSDLFRLFDRILLLSSGEIVYSG 226
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
9-246 |
5.05e-26 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 104.05 E-value: 5.05e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYRTGfwlnkkIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS---V 85
Cdd:PRK13647 4 IIEVEDLHFRYKDG------TKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENekwV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 86 RQRIGYL---PENAYYYDylTGWEFLQLiGGIFQILSSVQ-KKRIPELLDLVGLdrKTAQKKQLRQYSKGMMQRIGIAQA 161
Cdd:PRK13647 78 RSKVGLVfqdPDDQVFSS--TVWDDVAF-GPVNMGLDKDEvERRVEEALKAVRM--WDFRDKPPYHLSYGQKKRVAIAGV 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 162 LINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVG-----SLDQILG 236
Cdd:PRK13647 153 LAMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGdksllTDEDIVE 232
|
250
....*....|.
gi 738450152 237 RADV-YQVIVQ 246
Cdd:PRK13647 233 QAGLrLPLVAQ 243
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
5-232 |
6.51e-26 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 107.03 E-value: 6.51e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 5 SRQTVLETLNLQKTYrTGFWLNKKIeslkncTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS 84
Cdd:COG3845 1 MMPPALELRGITKRF-GGVVANDDV------SLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 85 ----VRQRIGY------LPENayyydyLTGWEFLQL----IGGIFQILSSVqKKRIPELLDLVGL----DRKTAQkkqLr 146
Cdd:COG3845 74 prdaIALGIGMvhqhfmLVPN------LTVAENIVLglepTKGGRLDRKAA-RARIRELSERYGLdvdpDAKVED---L- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 147 qySKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELl 226
Cdd:COG3845 143 --SVGEQQRVEILKALYRGARILILDEPTAVLTPQEADELFEILRRLAAEGKSIIFITHKLREVMAIADRVTVLRRGKV- 219
|
....*.
gi 738450152 227 cVGSLD 232
Cdd:COG3845 220 -VGTVD 224
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
9-240 |
1.96e-25 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 102.57 E-value: 1.96e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYRTgfwlnkKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSV 85
Cdd:PRK13652 3 LIETRDLCYSYSG------SKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKeniREV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 86 RQRIGYLPENAYYYDYLTGWEFLQLIGGIFQIL-SSVQKKRIPELLDLVGLDRktAQKKQLRQYSKGMMQRIGIAQALIN 164
Cdd:PRK13652 77 RKFVGLVFQNPDDQIFSPTVEQDIAFGPINLGLdEETVAHRVSSALHMLGLEE--LRDRVPHHLSGGEKKRVAIAGVIAM 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 738450152 165 DPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADV 240
Cdd:PRK13652 155 EPQVLVLDEPTAGLDPQGVKELIDFLNDLpETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQPDL 231
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
40-230 |
2.02e-25 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 107.02 E-value: 2.02e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 40 HEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDR--SVRQRIGYLPENAYYYDYLTGWEFLQLIGGIFQI 117
Cdd:TIGR01257 954 YENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNldAVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGR 1033
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 118 LSSVQKKRIPELLDLVGLDRKtaQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKqQG 197
Cdd:TIGR01257 1034 SWEEAQLEMEAMLEDTGLHHK--RNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYR-SG 1110
|
170 180 190
....*....|....*....|....*....|...
gi 738450152 198 KTIFFNSHILSDVEQICDRIALLARGELLCVGS 230
Cdd:TIGR01257 1111 RTIIMSTHHMDEADLLGDRIAIISQGRLYCSGT 1143
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
7-223 |
3.62e-25 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 100.59 E-value: 3.62e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 7 QTVLETLNLQKTyrtgFWL----NKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALIL--GQPI 80
Cdd:COG4778 2 TTLLEVENLSKT----FTLhlqgGKRLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRhdGGWV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 81 -----GDRSV----RQRIGYLPEnayyydyltgweFLQLIggifqilssvqkKRIPELlDLV-------GLDRKTAQKKQ 144
Cdd:COG4778 78 dlaqaSPREIlalrRRTIGYVSQ------------FLRVI------------PRVSAL-DVVaepllerGVDREEARARA 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 145 ---LRQ--------------YSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKT---IFfns 204
Cdd:COG4778 133 relLARlnlperlwdlppatFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAiigIF--- 209
|
250
....*....|....*....
gi 738450152 205 HILSDVEQICDRIALLARG 223
Cdd:COG4778 210 HDEEVREAVADRVVDVTPF 228
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
7-235 |
5.13e-25 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 101.40 E-value: 5.13e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 7 QTVLETLNLQKT--YRTGFWLNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI--GD 82
Cdd:PRK15112 2 ETLLEVRNLSKTfrYRTGWFRRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLhfGD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 83 RSVR-QRIGYLpenayYYDYLTGWEFLQLIGGIFQI-------LSSVQK-KRIPELLDLVGLDRKTAQKKQlRQYSKGMM 153
Cdd:PRK15112 82 YSYRsQRIRMI-----FQDPSTSLNPRQRISQILDFplrlntdLEPEQReKQIIETLRQVGLLPDHASYYP-HMLAPGQK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 154 QRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQ-QGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLD 232
Cdd:PRK15112 156 QRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEkQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTA 235
|
...
gi 738450152 233 QIL 235
Cdd:PRK15112 236 DVL 238
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
2-234 |
5.55e-25 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 102.48 E-value: 5.55e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 2 TNTSRQTVLETLNLQ-----KTYRTGFWLN-KKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALI 75
Cdd:PRK15079 1 VTEGKKVLLEVADLKvhfdiKDGKQWFWQPpKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAW 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 76 LGQPIGD------RSVRQRIGYLpenayYYDYLTGWEFLQLIGGI--------FQILSSVQ-KKRIPELLDLVGLdRKTA 140
Cdd:PRK15079 81 LGKDLLGmkddewRAVRSDIQMI-----FQDPLASLNPRMTIGEIiaeplrtyHPKLSRQEvKDRVKAMMLKVGL-LPNL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 141 QKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIAL 219
Cdd:PRK15079 155 INRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLqREMGLSLIFIAHDLAVVKHISDRVLV 234
|
250
....*....|....*
gi 738450152 220 LARGELLCVGSLDQI 234
Cdd:PRK15079 235 MYLGHAVELGTYDEV 249
|
|
| COG4674 |
COG4674 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
32-234 |
6.54e-25 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 100.58 E-value: 6.54e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS----VRQRIGYLPENAYYYDYLTGWEF 107
Cdd:COG4674 26 LNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDLTGLDeheiARLGIGRKFQKPTVFEELTVFEN 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 108 LQL--------IGGIFQILSSVQKKRIPELLDLVGLDRKTAQKKQLrqYSKGMMQRIGIAQALINDPELVFFDEPMSGLD 179
Cdd:COG4674 106 LELalkgdrgvFASLFARLTAEERDRIEEVLETIGLTDKADRLAGL--LSHGQKQWLEIGMLLAQDPKLLLLDEPVAGMT 183
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 738450152 180 PIGRYQVREIIQSLKQQgKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:COG4674 184 DAETERTAELLKSLAGK-HSVVVVEHDMEFVRQIARKVTVLHQGSVLAEGSLDEV 237
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
3-244 |
7.27e-25 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 100.84 E-value: 7.27e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 3 NTSRQTVLETLNLQKTYRTGFWLnkkieSLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD 82
Cdd:PRK13632 1 IKNKSVMIKVENVSFSYPNSENN-----ALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 83 ---RSVRQRIGYL---PENayyydyltgweflQLIGGIFQ--ILSSVQKKRIP--ELLDLV-GLDRKTAQKKQLRQ---- 147
Cdd:PRK13632 76 enlKEIRKKIGIIfqnPDN-------------QFIGATVEddIAFGLENKKVPpkKMKDIIdDLAKKVGMEDYLDKepqn 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 148 YSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQG-KTIFFNSHilsDVEQI--CDRIALLARGE 224
Cdd:PRK13632 143 LSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRkKTLISITH---DMDEAilADKVIVFSEGK 219
|
250 260
....*....|....*....|
gi 738450152 225 LLCVGSLDQILGRADVYQVI 244
Cdd:PRK13632 220 LIAQGKPKEILNNKEILEKA 239
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
31-225 |
8.37e-25 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 98.27 E-value: 8.37e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 31 SLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR----IGYLPENayyydyltgwe 106
Cdd:cd03215 15 AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAiragIAYVPED----------- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 107 flQLIGGIFQILSSVQKKRIPELLdlvgldrktaqkkqlrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQV 186
Cdd:cd03215 84 --RKREGLVLDLSVAENIALSSLL------------------SGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEI 143
|
170 180 190
....*....|....*....|....*....|....*....
gi 738450152 187 REIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:cd03215 144 YRLIRELADAGKAVLLISSELDELLGLCDRILVMYEGRI 182
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
6-233 |
2.26e-24 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 103.20 E-value: 2.26e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 6 RQTVLETLNLQKTYRTGFWLNKKIES--LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRP---TSGRALILGQPI 80
Cdd:TIGR00955 13 RVAQDGSWKQLVSRLRGCFCRERPRKhlLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKgvkGSGSVLLNGMPI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 81 GDRSVRQRIGYLPENAYYYDYLTGWEFLqliggIFQ-------ILSSVQKK-RIPELLDLVGL----DRKTAQKKQLRQY 148
Cdd:TIGR00955 93 DAKEMRAISAYVQQDDLFIPTLTVREHL-----MFQahlrmprRVTKKEKReRVDEVLQALGLrkcaNTRIGVPGRVKGL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 149 SKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSH-ILSDVEQICDRIALLARGELLC 227
Cdd:TIGR00955 168 SGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHqPSSELFELFDKIILMAEGRVAY 247
|
....*.
gi 738450152 228 VGSLDQ 233
Cdd:TIGR00955 248 LGSPDQ 253
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
31-239 |
2.63e-24 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 99.81 E-value: 2.63e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 31 SLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRAlilgqPIGD------------RSVRQRIGYL---PEN 95
Cdd:PRK13643 21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKV-----TVGDivvsstskqkeiKPVRKKVGVVfqfPES 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 96 AYYYDylTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKTAQKKQLrQYSKGMMQRIGIAQALINDPELVFFDEPM 175
Cdd:PRK13643 96 QLFEE--TVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLADEFWEKSPF-ELSGGQMRRVAIAGILAMEPEVLVLDEPT 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 738450152 176 SGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRAD 239
Cdd:PRK13643 173 AGLDPKARIEMMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQEVD 236
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
28-240 |
6.07e-24 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 97.64 E-value: 6.07e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 28 KIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD----RSVRQRIGYLPENAYYYDYLT 103
Cdd:PRK11614 17 KIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDwqtaKIMREAVAIVPEGRRVFSRMT 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 104 GWEFLQLiGGIFQILSSVQkKRIPELLDLVG-LDRKTAQKKQlrQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIG 182
Cdd:PRK11614 97 VEENLAM-GGFFAERDQFQ-ERIKWVYELFPrLHERRIQRAG--TMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPII 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 183 RYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADV 240
Cdd:PRK11614 173 IQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALLANEAV 230
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
32-237 |
1.00e-23 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 100.98 E-value: 1.00e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIG--DRSVRQR-IGYLPENAyyydyltgwefl 108
Cdd:COG4618 348 LRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSqwDREELGRhIGYLPQDV------------ 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 QLIGG-IFQILSsvqkkRIPELlDlvglDRK--TAQKK--------QLRQ-Y-----------SKGMMQRIGIAQALIND 165
Cdd:COG4618 416 ELFDGtIAENIA-----RFGDA-D----PEKvvAAAKLagvhemilRLPDgYdtrigeggarlSGGQRQRIGLARALYGD 485
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 738450152 166 PELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSdVEQICDRIALLARGELLCVGSLDQILGR 237
Cdd:COG4618 486 PRLVVLDEPNSNLDDEGEAALAAAIRALKARGATVVVITHRPS-LLAAVDKLLVLRDGRVQAFGPRDEVLAR 556
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
26-225 |
2.93e-23 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 95.35 E-value: 2.93e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 26 NKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIG--DRSV-RQRIGYLPENAYYYdYL 102
Cdd:cd03245 14 NQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRqlDPADlRRNIGYVPQDVTLF-YG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 103 TGWEFLQLIGGifqilsSVQKKRIPELLDLVGLDRKTAQKK-----QL----RQYSKGMMQRIGIAQALINDPELVFFDE 173
Cdd:cd03245 93 TLRDNITLGAP------LADDERILRAAELAGVTDFVNKHPngldlQIgergRGLSGGQRQAVALARALLNDPPILLLDE 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 738450152 174 PMSGLDPIGRyqvREIIQSLKQ--QGKTIFFNSHILSdVEQICDRIALLARGEL 225
Cdd:cd03245 167 PTSAMDMNSE---ERLKERLRQllGDKTLIIITHRPS-LLDLVDRIIVMDSGRI 216
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
8-240 |
3.04e-23 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 96.84 E-value: 3.04e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 8 TVLETLNLQKTYRTGfwlnkkIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI-----GD 82
Cdd:PRK13636 4 YILKVEELNYNYSDG------THALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIdysrkGL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 83 RSVRQRIGYL---PEN-----AYYYDYLTGWEFLQLIGGIFQilssvqkKRIPELLDLVGLDRktAQKKQLRQYSKGMMQ 154
Cdd:PRK13636 78 MKLRESVGMVfqdPDNqlfsaSVYQDVSFGAVNLKLPEDEVR-------KRVDNALKRTGIEH--LKDKPTHCLSFGQKK 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 155 RIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQ 233
Cdd:PRK13636 149 RVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMqKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKE 228
|
....*..
gi 738450152 234 ILGRADV 240
Cdd:PRK13636 229 VFAEKEM 235
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
4-237 |
6.12e-23 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 98.60 E-value: 6.12e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 4 TSRQTVLETLNLQKTY--RTGfWLNKKIESLK---NCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVrPTSGRALILGQ 78
Cdd:COG4172 270 PDAPPLLEARDLKVWFpiKRG-LFRRTVGHVKavdGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFDGQ 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 79 PIGD------RSVRQRIgylpenayyydyltgweflQLIggiFQ-------------------------ILSSVQK-KRI 126
Cdd:COG4172 348 DLDGlsrralRPLRRRM-------------------QVV---FQdpfgslsprmtvgqiiaeglrvhgpGLSAAERrARV 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 127 PELLDLVGLDRKTAQKkqlrqY----SKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIF 201
Cdd:COG4172 406 AEALEEVGLDPAARHR-----YphefSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLqREHGLAYL 480
|
250 260 270
....*....|....*....|....*....|....*.
gi 738450152 202 FNSHILSDVEQICDRIALLARGELLCVGSLDQILGR 237
Cdd:COG4172 481 FISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDA 516
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
34-230 |
4.25e-22 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 94.79 E-value: 4.25e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 34 NCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR----------------IGylpENAY 97
Cdd:PRK11432 24 NLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQRdicmvfqsyalfphmsLG---ENVG 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 98 YydyltGwefLQLIGgifqILSSVQKKRIPELLDLVGLDrkTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSG 177
Cdd:PRK11432 101 Y-----G---LKMLG----VPKEERKQRVKEALELVDLA--GFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 738450152 178 LDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVGS 230
Cdd:PRK11432 167 LDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGS 220
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
36-239 |
4.89e-22 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 92.13 E-value: 4.89e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 36 TLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQRigylP------ENAYYyDYLTGWeflQ 109
Cdd:COG3840 19 DLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAER----PvsmlfqENNLF-PHLTVA---Q 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 110 LIGgiFQI-----LSSVQKKRIPELLDLVGL----DRKTAQkkqlrqYSKGMMQRIGIAQALINDPELVFFDEPMSGLDP 180
Cdd:COG3840 91 NIG--LGLrpglkLTAEQRAQVEQALERVGLagllDRLPGQ------LSGGQRQRVALARCLVRKRPILLLDEPFSALDP 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 181 IGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRAD 239
Cdd:COG3840 163 ALRQEMLDLVDELcRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEP 222
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
31-235 |
5.61e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 93.13 E-value: 5.61e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 31 SLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS----VRQRIGYL---PENAYY----- 98
Cdd:PRK13644 17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSklqgIRKLVGIVfqnPETQFVgrtve 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 99 YDYLTGWEFLqliggifqILSSVQ-KKRIPELLDLVGLDRktAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSG 177
Cdd:PRK13644 97 EDLAFGPENL--------CLPPIEiRKRVDRALAEIGLEK--YRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSM 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 178 LDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVeQICDRIALLARGELLCVGSLDQIL 235
Cdd:PRK13644 167 LDPDSGIAVLERIKKLHEKGKTIVYITHNLEEL-HDADRIIVMDRGKIVLEGEPENVL 223
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
32-225 |
5.92e-22 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 90.84 E-value: 5.92e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD--RSVRQRIGYLPENAYYYDyltgweflq 109
Cdd:cd03247 18 LKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDleKALSSLISVLNQRPYLFD--------- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 110 liggifqilssvqkkriPELLDLVGldrktaqkkqlRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREI 189
Cdd:cd03247 89 -----------------TTLRNNLG-----------RRFSGGERQRLALARILLQDAPIVLLDEPTVGLDPITERQLLSL 140
|
170 180 190
....*....|....*....|....*....|....*..
gi 738450152 190 I-QSLKqqGKTIFFNSHILSDVEQIcDRIALLARGEL 225
Cdd:cd03247 141 IfEVLK--DKTLIWITHHLTGIEHM-DKILFLENGKI 174
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
18-253 |
7.21e-22 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 93.02 E-value: 7.21e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 18 TYRTGFwlnkkiESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIgDRSVRQR-IGYLPENA 96
Cdd:PRK15056 15 TWRNGH------TALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPT-RQALQKNlVAYVPQSE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 97 YyydylTGWEFLQLIG-----------GIFQILSSVQKKRIPELLDLVglDRKTAQKKQLRQYSKGMMQRIGIAQALIND 165
Cdd:PRK15056 88 E-----VDWSFPVLVEdvvmmgryghmGWLRRAKKRDRQIVTAALARV--DMVEFRHRQIGELSGGQKKRVFLARAIAQQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 166 PELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDrIALLARGELLCVGSLDQILGRAD------ 239
Cdd:PRK15056 161 GQVILLDEPFTGVDVKTEARIISLLRELRDEGKTMLVSTHNLGSVTEFCD-YTVMVKGTVLASGPTETTFTAENlelafs 239
|
250
....*....|....*
gi 738450152 240 -VYQVIVQGGGEEQL 253
Cdd:PRK15056 240 gVLRHVALNGSEESI 254
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
8-235 |
9.70e-22 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 92.00 E-value: 9.70e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 8 TVLETLNLQKTYRtgfwlNKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQ 87
Cdd:PRK11231 1 MTLRTENLTVGYG-----TKRI--LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 88 ---RIGYLPEN-------------AY-YYDYLTGWEFL-----QLIGgifqilSSVQKKRIPELLDlvgldrktaqkKQL 145
Cdd:PRK11231 74 larRLALLPQHhltpegitvrelvAYgRSPWLSLWGRLsaednARVN------QAMEQTRINHLAD-----------RRL 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 146 RQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK11231 137 TDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGHV 216
|
250
....*....|
gi 738450152 226 LCVGSLDQIL 235
Cdd:PRK11231 217 MAQGTPEEVM 226
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
32-235 |
9.83e-22 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 94.33 E-value: 9.83e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD------RSV-RQRIGYLPENAYYYDYLTG 104
Cdd:PRK10070 44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKisdaelREVrRKKIAMVFQSFALMPHMTV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 105 WEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKTAQKKQlrQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRY 184
Cdd:PRK10070 124 LDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPD--ELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRT 201
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 738450152 185 QVR-EIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL 235
Cdd:PRK10070 202 EMQdELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEIL 253
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
29-229 |
1.31e-21 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 94.85 E-value: 1.31e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 29 IESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPigdrsvrqrigylpenayyYDYLTGWEFL 108
Cdd:PRK09700 18 VHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNIN-------------------YNKLDHKLAA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 QL-IGGIFQILS-----SVQ------------------------KKRIPELLDLVGLDRKTAQKkqLRQYSKGMMQRIGI 158
Cdd:PRK09700 79 QLgIGIIYQELSvidelTVLenlyigrhltkkvcgvniidwremRVRAAMMLLRVGLKVDLDEK--VANLSISHKQMLEI 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 738450152 159 AQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVG 229
Cdd:PRK09700 157 AKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSG 227
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
30-260 |
1.32e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 92.54 E-value: 1.32e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 30 ESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD-------RSVRQRIGYL---PENAYYY 99
Cdd:PRK13646 21 QAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHktkdkyiRPVRKRIGMVfqfPESQLFE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 100 DYLTGweflQLIGGI--FQI-LSSVQKKRIPELLDLvGLDRKTAQKKQLrQYSKGMMQRIGIAQALINDPELVFFDEPMS 176
Cdd:PRK13646 101 DTVER----EIIFGPknFKMnLDEVKNYAHRLLMDL-GFSRDVMSQSPF-QMSGGQMRKIAIVSILAMNPDIIVLDEPTA 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 177 GLDPIGRYQVREIIQSLK-QQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRadvyqvivqgggEEQLQQ 255
Cdd:PRK13646 175 GLDPQSKRQVMRLLKSLQtDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKD------------KKKLAD 242
|
....*
gi 738450152 256 WLLGL 260
Cdd:PRK13646 243 WHIGL 247
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
9-234 |
2.43e-21 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 92.98 E-value: 2.43e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR 88
Cdd:PRK11607 19 LLEIRNLTKSF-------DGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 igylPENAYYYDY--LTGWEFLQLIG-GIFQ-ILSSVQ-KKRIPELLDLVGLDRKTAQKKQlrQYSKGMMQRIGIAQALI 163
Cdd:PRK11607 92 ----PINMMFQSYalFPHMTVEQNIAfGLKQdKLPKAEiASRVNEMLGLVHMQEFAKRKPH--QLSGGQRQRVALARSLA 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 738450152 164 NDPELVFFDEPMSGLDPIGRYQVR-EIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:PRK11607 166 KRPKLLLLDEPMGALDKKLRDRMQlEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEI 237
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
30-232 |
2.85e-21 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 93.54 E-value: 2.85e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 30 ESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQ----RIGYLPEN--AYyydylt 103
Cdd:COG1129 266 GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRDairaGIAYVPEDrkGE------ 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 104 gweflqligGIFQILS-------SVQKKripeLLDLVGLDRKtAQKKQLRQYSK-------GMMQRIG-----------I 158
Cdd:COG1129 340 ---------GLVLDLSirenitlASLDR----LSRGGLLDRR-RERALAEEYIKrlriktpSPEQPVGnlsggnqqkvvL 405
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738450152 159 AQALINDPELVFFDEPMSGLDpIG-RYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELlcVGSLD 232
Cdd:COG1129 406 AKWLATDPKVLILDEPTRGID-VGaKAEIYRLIRELAAEGKAVIVISSELPELLGLSDRILVMREGRI--VGELD 477
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
32-234 |
4.17e-21 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 90.84 E-value: 4.17e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSV---RQRIGYL---PENayyydyltgw 105
Cdd:PRK13635 23 LKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVwdvRRQVGMVfqnPDN---------- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 106 eflQLIGGIFQ-----------ILSSVQKKRIPELLDLVG----LDRKTAQkkqlrqYSKGMMQRIGIAQALINDPELVF 170
Cdd:PRK13635 93 ---QFVGATVQddvafglenigVPREEMVERVDQALRQVGmedfLNREPHR------LSGGQKQRVAIAGVLALQPDIII 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738450152 171 FDEPMSGLDPIGRYQVREIIQSLKQQGK-TIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQI 234
Cdd:PRK13635 164 LDEATSMLDPRGRREVLETVRQLKEQKGiTVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEI 227
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
26-235 |
4.39e-21 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 90.65 E-value: 4.39e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 26 NKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRAlilgQPIGDRSVrqrigyLPENAYYYDYLTGW 105
Cdd:PRK13546 34 NKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKV----DRNGEVSV------IAISAGLSGQLTGI 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 106 ---EFLQLIGGIFQilsSVQKKRIPELLDLVGLDRKTAQKkqLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIG 182
Cdd:PRK13546 104 eniEFKMLCMGFKR---KEIKAMTPKIIEFSELGEFIYQP--VKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTF 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 738450152 183 RYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL 235
Cdd:PRK13546 179 AQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVL 231
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
32-235 |
5.66e-21 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 89.77 E-value: 5.66e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD-----RSVRQRIGYLPENAYYYDYLTGWE 106
Cdd:PRK09493 17 LHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDpkvdeRLIRQEAGMVFQQFYLFPHLTALE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 107 flQLIGGIFQI--LSSVQKKRIP-ELLDLVGL-DRKTAQKKQLrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDPIG 182
Cdd:PRK09493 97 --NVMFGPLRVrgASKEEAEKQArELLAKVGLaERAHHYPSEL---SGGQQQRVAIARALAVKPKLMLFDEPTSALDPEL 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 738450152 183 RYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL 235
Cdd:PRK09493 172 RHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLI 224
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
37-229 |
5.78e-21 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 89.09 E-value: 5.78e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 37 LIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQ-----PIGDRSVRQrigYLPENAYYyDYLTGWEFLQLI 111
Cdd:cd03298 19 LTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVdvtaaPPADRPVSM---LFQENNLF-AHLTVEQNVGLG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 112 GGIFQILSSVQKKRIPELLDLVGLDRKtaQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQ 191
Cdd:cd03298 95 LSPGLKLTAEDRQAIEVALARVGLAGL--EKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVL 172
|
170 180 190
....*....|....*....|....*....|....*....
gi 738450152 192 SL-KQQGKTIFFNSHILSDVEQICDRIALLARGELLCVG 229
Cdd:cd03298 173 DLhAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
1-230 |
6.77e-21 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 91.55 E-value: 6.77e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 1 MTNTSRQTVLETLNLQKTYRTgfwlnKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI 80
Cdd:PRK09452 6 KQPSSLSPLVELRGISKSFDG-----KEV--ISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 81 GDRSVRQRigylPENAYYYDY-----LTGWE---FlqliGGIFQILSSVQ-KKRIPELLDLVGLDrKTAQKKQlRQYSKG 151
Cdd:PRK09452 79 THVPAENR----HVNTVFQSYalfphMTVFEnvaF----GLRMQKTPAAEiTPRVMEALRMVQLE-EFAQRKP-HQLSGG 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 152 MMQRIGIAQALINDPELVFFDEPMSGLDpigrYQVREIIQS-LK----QQGKTIFFNSHilsDVEQ---ICDRIALLARG 223
Cdd:PRK09452 149 QQQRVAIARAVVNKPKVLLLDESLSALD----YKLRKQMQNeLKalqrKLGITFVFVTH---DQEEaltMSDRIVVMRDG 221
|
....*..
gi 738450152 224 ELLCVGS 230
Cdd:PRK09452 222 RIEQDGT 228
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
26-242 |
1.01e-20 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 88.83 E-value: 1.01e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 26 NKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPENAYYYDyl 102
Cdd:cd03251 12 GDGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDytlASLRRQIGLVSQDVFLFN-- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 103 tgweflqliGGIF-------------QILSSVQK-------KRIPELLDLVGLDRKTaqkkqlrQYSKGMMQRIGIAQAL 162
Cdd:cd03251 90 ---------DTVAeniaygrpgatreEVEEAARAanahefiMELPEGYDTVIGERGV-------KLSGGQRQRIAIARAL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 163 INDPELVFFDEPMSGLDPIGRYQVREIIQSLkQQGKTIFFNSHILSDVEQIcDRIALLARGELLCVGSLDQILGRADVYQ 242
Cdd:cd03251 154 LKDPPILILDEATSALDTESERLVQAALERL-MKNRTTFVIAHRLSTIENA-DRIVVLEDGKIVERGTHEELLAQGGVYA 231
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
10-243 |
1.09e-20 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 89.40 E-value: 1.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLqkTYRTGfwlNKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQ-- 87
Cdd:COG4559 2 LEAENL--SVRLG---GRTL--LDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWEla 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 88 -RIGYLPENAyyydYL----TGWEFLQLiGGIFQILSSVQKKRIP-ELLDLVGLDRKTAqkkqlRQY---SKGMMQRIGI 158
Cdd:COG4559 75 rRRAVLPQHS----SLafpfTVEEVVAL-GRAPHGSSAAQDRQIVrEALALVGLAHLAG-----RSYqtlSGGEQQRVQL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 159 AQALI-------NDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFnshILSDVE---QICDRIALLARGELLCV 228
Cdd:COG4559 145 ARVLAqlwepvdGGPRWLFLDEPTSALDLAHQHAVLRLARQLARRGGGVVA---VLHDLNlaaQYADRILLLHQGRLVAQ 221
|
250
....*....|....*...
gi 738450152 229 GSLDQILGRA---DVYQV 243
Cdd:COG4559 222 GTPEEVLTDElleRVYGA 239
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
23-235 |
1.10e-20 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 88.44 E-value: 1.10e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 23 FWLNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDR---SVRQRIGYLPENAYYY 99
Cdd:cd03254 10 FSYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDIsrkSLRSMIGVVLQDTFLF 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 100 DyltgweflqliGGIFQIL----SSVQKKRIPELLDLVGLDR---------KTAQKKQLRQYSKGMMQRIGIAQALINDP 166
Cdd:cd03254 90 S-----------GTIMENIrlgrPNATDEEVIEAAKEAGAHDfimklpngyDTVLGENGGNLSQGERQLLAIARAMLRDP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 167 ELVFFDEPMSGLDPIGRYQVREIIQSLkQQGKTIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQIL 235
Cdd:cd03254 159 KILILDEATSNIDTETEKLIQEALEKL-MKGRTSIIIAHRLSTIKN-ADKILVLDDGKIIEEGTHDELL 225
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
32-220 |
1.86e-20 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 91.58 E-value: 1.86e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSV---RQRIGYLPENAYyydyltgwefl 108
Cdd:TIGR02857 338 LRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADAdswRDQIAWVPQHPF----------- 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 qliggIFQ--ILSSVQKKR-------IPELLDLVGLDRKTAQKKQL---------RQYSKGMMQRIGIAQALINDPELVF 170
Cdd:TIGR02857 407 -----LFAgtIAENIRLARpdasdaeIREALERAGLDEFVAALPQGldtpigeggAGLSGGQAQRLALARAFLRDAPLLL 481
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 738450152 171 FDEPMSGLDPIGRYQVREIIQSLKqQGKTIFFNSHILSDVEQiCDRIALL 220
Cdd:TIGR02857 482 LDEPTAHLDAETEAEVLEALRALA-QGRTVLLVTHRLALAAL-ADRIVVL 529
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
37-235 |
2.43e-20 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 90.29 E-value: 2.43e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 37 LIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVR---QRIGYLPENAYYYDYLTGWEFLQLiG- 112
Cdd:PRK09536 24 LSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARaasRRVASVPQDTSLSFEFDVRQVVEM-Gr 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 113 ----GIFQILSSVQKKRIPELLDLVGLDRKTAQkkQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDpIGRyQVR- 187
Cdd:PRK09536 103 tphrSRFDTWTETDRAAVERAMERTGVAQFADR--PVTSLSGGERQRVLLARALAQATPVLLLDEPTASLD-INH-QVRt 178
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 738450152 188 -EIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL 235
Cdd:PRK09536 179 lELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVL 227
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
46-239 |
2.62e-20 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 89.77 E-value: 2.62e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 46 GLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQ-------RIGYLPENAYYYDYLTGWEFLQLigGIFQIL 118
Cdd:COG4148 29 ALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDSARGIflpphrrRIGYVFQEARLFPHLSVRGNLLY--GRKRAP 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 119 SSVQKKRIPELLDLVG----LDRKTAqkkQLrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLK 194
Cdd:COG4148 107 RAERRISFDEVVELLGighlLDRRPA---TL---SGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEILPYLERLR 180
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 738450152 195 QQGKT-IFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRAD 239
Cdd:COG4148 181 DELDIpILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPD 226
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
32-239 |
3.73e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 88.54 E-value: 3.73e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRAlilgqPIGDR------------SVRQRIGYL---PENa 96
Cdd:PRK13634 23 LYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTV-----TIGERvitagkknkklkPLRKKVGIVfqfPEH- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 97 yyydyltgweflQLI----------GGI-FQILSSVQKKRIPELLDLVGLDRKTAQKKQLrQYSKGMMQRIGIAQALIND 165
Cdd:PRK13634 97 ------------QLFeetvekdicfGPMnFGVSEEDAKQKAREMIELVGLPEELLARSPF-ELSGGQMRRVAIAGVLAME 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738450152 166 PELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRAD 239
Cdd:PRK13634 164 PEVLVLDEPTAGLDPKGRKEMMEMFYKLhKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPD 238
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
14-235 |
5.18e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 88.22 E-value: 5.18e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYrtgfwlNKK----IESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGR----------------- 72
Cdd:PRK13651 7 NIVKIF------NKKlpteLKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTiewifkdeknkkktkek 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 73 -----ALILGQPIGDR-----SVRQRIGYLPENAYYYDYLTGWEFLQLIGGI-FQILSSVQKKRIPELLDLVGLDRKTAQ 141
Cdd:PRK13651 81 ekvleKLVIQKTRFKKikkikEIRRRVGVVFQFAEYQLFEQTIEKDIIFGPVsMGVSKEEAKKRAAKYIELVGLDESYLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 142 KKQLrQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLA 221
Cdd:PRK13651 161 RSPF-ELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNVLEWTKRTIFFK 239
|
250
....*....|....
gi 738450152 222 RGELLCVGSLDQIL 235
Cdd:PRK13651 240 DGKIIKDGDTYDIL 253
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
32-223 |
5.21e-20 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 89.97 E-value: 5.21e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVR-----------QRIGYLPEnayyyd 100
Cdd:PRK11288 20 LDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTaalaagvaiiyQELHLVPE------ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 101 yLTGWEFLQL-----IGGIfqILSSVQKKRIPELLDLVGLDRKTAQKkqLRQYSKGMMQRIGIAQALINDPELVFFDEPM 175
Cdd:PRK11288 94 -MTVAENLYLgqlphKGGI--VNRRLLNYEAREQLEHLGVDIDPDTP--LKYLSIGQRQMVEIAKALARNARVIAFDEPT 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 738450152 176 SGLdpigryQVREI------IQSLKQQGKTIFFNSHILSDVEQICDRIALLARG 223
Cdd:PRK11288 169 SSL------SAREIeqlfrvIRELRAEGRVILYVSHRMEEIFALCDAITVFKDG 216
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
32-223 |
5.36e-20 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 87.11 E-value: 5.36e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALI------LGQPIGD-----RSVRQRIGYLPENAYYYD 100
Cdd:PRK11264 19 LHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVgditidTARSLSQqkgliRQLRQHVGFVFQNFNLFP 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 101 YLTGWEflQLIGGIFQILSSVQK---KRIPELLDLVGLDRKtaQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSG 177
Cdd:PRK11264 99 HRTVLE--NIIEGPVIVKGEPKEeatARARELLAKVGLAGK--ETSYPRRLSGGQQQRVAIARALAMRPEVILFDEPTSA 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 738450152 178 LDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARG 223
Cdd:PRK11264 175 LDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQG 220
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
30-259 |
6.17e-20 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 87.33 E-value: 6.17e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 30 ESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIgdRSVRQRIGYLP------------ENAY 97
Cdd:PRK10619 19 EVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTI--NLVRDKDGQLKvadknqlrllrtRLTM 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 98 YYDYLTGWEFLQLIGGIF----QIL---SSVQKKRIPELLDLVGLDRKtAQKKQLRQYSKGMMQRIGIAQALINDPELVF 170
Cdd:PRK10619 97 VFQHFNLWSHMTVLENVMeapiQVLglsKQEARERAVKYLAKVGIDER-AQGKYPVHLSGGQQQRVSIARALAMEPEVLL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 171 FDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADvyqvivqgggE 250
Cdd:PRK10619 176 FDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQ----------S 245
|
....*....
gi 738450152 251 EQLQQWLLG 259
Cdd:PRK10619 246 PRLQQFLKG 254
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
30-225 |
1.22e-19 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 88.95 E-value: 1.22e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 30 ESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQRIG----YLPEN----AYYYDY 101
Cdd:PRK15439 277 EGFRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQRLArglvYLPEDrqssGLYLDA 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 102 LTGWEFLQLIGGI--FQILSSVQKKRIPELLDLVGLdrKTAQKKQ-LRQYSKGMMQRIGIAQALINDPELVFFDEPMSGL 178
Cdd:PRK15439 357 PLAWNVCALTHNRrgFWIKPARENAVLERYRRALNI--KFNHAEQaARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGV 434
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 738450152 179 DPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK15439 435 DVSARNDIYQLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
14-239 |
1.32e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 86.72 E-value: 1.32e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRTGFWLNKKieSLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD-------RSVR 86
Cdd:PRK13649 7 NVSYTYQAGTPFEGR--ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITStsknkdiKQIR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 87 QRIGYL---PENAYYYDylTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKTAQKKQLrQYSKGMMQRIGIAQALI 163
Cdd:PRK13649 85 KKVGLVfqfPESQLFEE--TVLKDVAFGPQNFGVSQEEAEALAREKLALVGISESLFEKNPF-ELSGGQMRRVAIAGILA 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 164 NDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRAD 239
Cdd:PRK13649 162 MEPKILVLDEPTAGLDPKGRKELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQDVD 237
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
14-226 |
1.46e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 86.81 E-value: 1.46e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRTGFWLNKKieSLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI-------GDRSVR 86
Cdd:PRK13641 7 NVDYIYSPGTPMEKK--GLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHItpetgnkNLKKLR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 87 QRIGYL---PENAYYYD-YLTGWEFlqligGIFQILSSVQKKRIPEL--LDLVGLDRKTAQKKQLrQYSKGMMQRIGIAQ 160
Cdd:PRK13641 85 KKVSLVfqfPEAQLFENtVLKDVEF-----GPKNFGFSEDEAKEKALkwLKKVGLSEDLISKSPF-ELSGGQMRRVAIAG 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 161 ALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELL 226
Cdd:PRK13641 159 VMAYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLI 224
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
5-201 |
1.67e-19 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 85.64 E-value: 1.67e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 5 SRQTVLETLNLQKTYRTGfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS 84
Cdd:PRK11629 1 MNKILLQCDNLCKRYQEG---SVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 85 VR-------QRIGYLPENAYYYDYLTGWEFLQ---LIGGifqILSSVQKKRIPELLDLVGLDRKTAQKKQlrQYSKGMMQ 154
Cdd:PRK11629 78 SAakaelrnQKLGFIYQFHHLLPDFTALENVAmplLIGK---KKPAEINSRALEMLAAVGLEHRANHRPS--ELSGGERQ 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 738450152 155 RIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIF 201
Cdd:PRK11629 153 RVAIARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAF 199
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
26-232 |
2.23e-19 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 84.12 E-value: 2.23e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 26 NKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGI--VRPTSGRALILGQPIGDRSV--RQRIGylpenayyydy 101
Cdd:cd03217 12 GKEI--LKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHpkYEVTEGEILFKGEDITDLPPeeRARLG----------- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 102 ltgweflqlIGGIFQILSSVQKKRIPELLDLVGLDrktaqkkqlrqYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPI 181
Cdd:cd03217 79 ---------IFLAFQYPPEIPGVKNADFLRYVNEG-----------FSGGEKKRNEILQLLLLEPDLAILDEPDSGLDID 138
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 738450152 182 GRYQVREIIQSLKQQGKTIFFNSH---ILSDVEQicDRIALLARGELLCVGSLD 232
Cdd:cd03217 139 ALRLVAEVINKLREEGKSVLIITHyqrLLDYIKP--DRVHVLYDGRIVKSGDKE 190
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
28-234 |
2.43e-19 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 87.10 E-value: 2.43e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 28 KIESLKNCTLIVHEGETFGLLGPNGAG--KTTLLKTLLGivrPTSGRA--LILGQPIGDRSVRQRIG-YLPENAYYYDYL 102
Cdd:NF000106 25 EVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G---PDAGRRpwRF*TWCANRRALRRTIG*HRPVR*GRRESF 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 103 TGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRktAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIG 182
Cdd:NF000106 102 SGRENLYMIGR*LDLSRKDARARADELLERFSLTE--AAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRT 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 738450152 183 RYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:NF000106 180 RNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
32-212 |
3.73e-19 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 85.14 E-value: 3.73e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS-----VRQRIGYLPenayYYDYLTGWE 106
Cdd:PRK11248 17 LEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGaergvVFQNEGLLP----WRNVQDNVA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 107 F-LQLIGgifqILSSVQKKRIPELLDLVGLDrkTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQ 185
Cdd:PRK11248 93 FgLQLAG----VEKMQRLEIAHQMLKKVGLE--GAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQ 166
|
170 180
....*....|....*....|....*...
gi 738450152 186 VREIIQSLKQ-QGKTIFFNSHilsDVEQ 212
Cdd:PRK11248 167 MQTLLLKLWQeTGKQVLLITH---DIEE 191
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
32-235 |
3.95e-19 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 87.79 E-value: 3.95e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIG--DR-SVRQRIGYLPENayyydyltgwefL 108
Cdd:TIGR01842 334 LRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKqwDReTFGKHIGYLPQD------------V 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 QLIGG-----IFQILSSVQKKRIPELLDLVGLDRKTAQKKQlrQY-----------SKGMMQRIGIAQALINDPELVFFD 172
Cdd:TIGR01842 402 ELFPGtvaenIARFGENADPEKIIEAAKLAGVHELILRLPD--GYdtvigpggatlSGGQRQRIALARALYGDPKLVVLD 479
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 738450152 173 EPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQIcDRIALLARGELLCVGSLDQIL 235
Cdd:TIGR01842 480 EPNSNLDEEGEQALANAIKALKARGITVVVITHRPSLLGCV-DKILVLQDGRIARFGERDEVL 541
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
7-233 |
5.07e-19 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 84.68 E-value: 5.07e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 7 QTVLETLNLQKTYRTGfwlnkkiESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIV---RPTSGRALILGQPI--- 80
Cdd:PRK09984 2 QTIIRVEKLAKTFNQH-------QALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLItgdKSAGSHIELLGRTVqre 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 81 ----GD-RSVRQRIGYLPENAYYYDYLTGWEFLqLIGGI---------FQILSSVQKKRIPELLDLVGLDRKTAQKkqLR 146
Cdd:PRK09984 75 grlaRDiRKSRANTGYIFQQFNLVNRLSVLENV-LIGALgstpfwrtcFSWFTREQKQRALQALTRVGMVHFAHQR--VS 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 147 QYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK09984 152 TLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNdGITVVVTLHQVDYALRYCERIVALRQGHV 231
|
....*...
gi 738450152 226 LCVGSLDQ 233
Cdd:PRK09984 232 FYDGSSQQ 239
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
30-199 |
6.38e-19 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 83.91 E-value: 6.38e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 30 ESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALI------LGQPIGD---RSVRQRIGYLPENAYYYD 100
Cdd:PRK11124 16 QALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIagnhfdFSKTPSDkaiRELRRNVGMVFQQYNLWP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 101 YLTGWEflQLIGGIFQILSSVQ---KKRIPELLDLVGLDRKtAQKKQLrQYSKGMMQRIGIAQALINDPELVFFDEPMSG 177
Cdd:PRK11124 96 HLTVQQ--NLIEAPCRVLGLSKdqaLARAEKLLERLRLKPY-ADRFPL-HLSGGQQQRVAIARALMMEPQVLLFDEPTAA 171
|
170 180
....*....|....*....|..
gi 738450152 178 LDPIGRYQVREIIQSLKQQGKT 199
Cdd:PRK11124 172 LDPEITAQIVSIIRELAETGIT 193
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
32-245 |
9.32e-19 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 86.70 E-value: 9.32e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---------------------RSVRQRIg 90
Cdd:TIGR00958 497 LKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQydhhylhrqvalvgqepvlfsGSVRENI- 575
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 91 ylpenAYYYDYLTGWEflqliggifqILSSVQKKR----IPELLDlvGLDRKTAQKKQlrQYSKGMMQRIGIAQALINDP 166
Cdd:TIGR00958 576 -----AYGLTDTPDEE----------IMAAAKAANahdfIMEFPN--GYDTEVGEKGS--QLSGGQKQRIAIARALVRKP 636
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 167 ELVFFDEPMSGLDPIGRYQVReiiQSLKQQGKTIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQILGRADVYQVIV 245
Cdd:TIGR00958 637 RVLILDEATSALDAECEQLLQ---ESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMEDQGCYKHLV 711
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
30-246 |
1.06e-18 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 83.30 E-value: 1.06e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 30 ESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIG---DRSVRQRIGY-LPENAYYYDyltgw 105
Cdd:cd03252 16 VILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLAladPAWLRRQVGVvLQENVLFNR----- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 106 eflQLIGGIFQILSSVQKKRIPELLDLVG---------LDRKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMS 176
Cdd:cd03252 91 ---SIRDNIALADPGMSMERVIEAAKLAGahdfiselpEGYDTIVGEQGAGLSGGQRQRIAIARALIHNPRILIFDEATS 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 738450152 177 GLDpigrYQVREIIQSLKQQ---GKTIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQILGRADVYQVIVQ 246
Cdd:cd03252 168 ALD----YESEHAIMRNMHDicaGRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDELLAENGLYAYLYQ 235
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
32-279 |
1.09e-18 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 85.14 E-value: 1.09e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR-IGYLPENAYYYDYLTGWEFLQL 110
Cdd:PRK10851 18 LNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDRkVGFVFQHYALFRHMTVFDNIAF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 111 igGIfQIL-------SSVQKKRIPELLDLVGL----DRKTAQkkqlrqYSKGMMQRIGIAQALINDPELVFFDEPMSGLD 179
Cdd:PRK10851 98 --GL-TVLprrerpnAAAIKAKVTQLLEMVQLahlaDRYPAQ------LSGGQKQRVALARALAVEPQILLLDEPFGALD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 180 PIGRYQVREIIQSLKQQGK-TIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI------------LGRADVYQVIVQ 246
Cdd:PRK10851 169 AQVRKELRRWLRQLHEELKfTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVwrepatrfvlefMGEVNRLQGTIR 248
|
250 260 270
....*....|....*....|....*....|...
gi 738450152 247 GGgeeqlQQWLLGLHWRDNcWHGQLQGEPDAFL 279
Cdd:PRK10851 249 GG-----QFHVGAHRWPLG-YTPAYQGPVDLFL 275
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
4-241 |
1.18e-18 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 86.33 E-value: 1.18e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 4 TSRQTVLETLNLQK-TYRTGFwlNKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD 82
Cdd:TIGR01193 465 TELNNLNGDIVINDvSYSYGY--GSNI--LSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKD 540
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 83 RS---VRQRIGYLPENAYYYDyltgweflqliGGIFQ--ILSSVQKKRIPELLDLVGLDRKTAQKKQLRQ---------- 147
Cdd:TIGR01193 541 IDrhtLRQFINYLPQEPYIFS-----------GSILEnlLLGAKENVSQDEIWAACEIAEIKDDIENMPLgyqtelseeg 609
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 148 --YSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRyqvREIIQSL-KQQGKTIFFNSHILSdVEQICDRIALLARGE 224
Cdd:TIGR01193 610 ssISGGQKQRIALARALLTDSKVLILDESTSNLDTITE---KKIVNNLlNLQDKTIIFVAHRLS-VAKQSDKIIVLDHGK 685
|
250
....*....|....*..
gi 738450152 225 LLCVGSLDQILGRADVY 241
Cdd:TIGR01193 686 IIEQGSHDELLDRNGFY 702
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
30-199 |
1.44e-18 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 83.14 E-value: 1.44e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 30 ESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILG------QPIGD---RSVRQRIGYLPENAYYYD 100
Cdd:COG4161 16 QALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGhqfdfsQKPSEkaiRLLRQKVGMVFQQYNLWP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 101 YLTGWEflQLIGGIFQIL---SSVQKKRIPELLDLVGLDRKtAQKKQLrQYSKGMMQRIGIAQALINDPELVFFDEPMSG 177
Cdd:COG4161 96 HLTVME--NLIEAPCKVLglsKEQAREKAMKLLARLRLTDK-ADRFPL-HLSGGQQQRVAIARALMMEPQVLLFDEPTAA 171
|
170 180
....*....|....*....|..
gi 738450152 178 LDPIGRYQVREIIQSLKQQGKT 199
Cdd:COG4161 172 LDPEITAQVVEIIRELSQTGIT 193
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
7-237 |
1.49e-18 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 84.63 E-value: 1.49e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 7 QTVLETLNLQKTY--RTGFWLNKK-IESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQ----- 78
Cdd:PRK11308 3 QPLLQAIDLKKHYpvKRGLFKPERlVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQdllka 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 79 -PIGDRSVRQRIGYLPENAYyydyltgwEFL---QLIGGIF----QI---LSSVQKK-RIPELLDLVGLdRKTAQKKQLR 146
Cdd:PRK11308 83 dPEAQKLLRQKIQIVFQNPY--------GSLnprKKVGQILeeplLIntsLSAAERReKALAMMAKVGL-RPEHYDRYPH 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 147 QYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIF-FNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK11308 154 MFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYvFISHDLSVVEHIADEVMVMYLGRC 233
|
250
....*....|..
gi 738450152 226 LCVGSLDQILGR 237
Cdd:PRK11308 234 VEKGTKEQIFNN 245
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
32-242 |
2.00e-18 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 85.60 E-value: 2.00e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPENAYyydyltgwefl 108
Cdd:COG1132 356 LKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDltlESLRRQIGVVPQDTF----------- 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 qliggIFQ------IL---SSVQKKRIPELLDLVGLDRKTAQKKQlrQY-----------SKGMMQRIGIAQALINDPEL 168
Cdd:COG1132 425 -----LFSgtirenIRygrPDATDEEVEEAAKAAQAHEFIEALPD--GYdtvvgergvnlSGGQRQRIAIARALLKDPPI 497
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 738450152 169 VFFDEPMSGLDPIGRYQVREIIQSLKqQGKTIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQILGRADVYQ 242
Cdd:COG1132 498 LILDEATSALDTETEALIQEALERLM-KGRTTIVIAHRLSTIRN-ADRILVLDDGRIVEQGTHEELLARGGLYA 569
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
32-207 |
2.55e-18 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 82.47 E-value: 2.55e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRAlilgqpigDRSVRQRIGYLPENAYYYDY--LTGWEFLQ 109
Cdd:PRK09544 20 LSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI--------KRNGKLRIGYVPQKLYLDTTlpLTVNRFLR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 110 LIGGifqilssVQKKRIpelldLVGLDRKTAQK---KQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQV 186
Cdd:PRK09544 92 LRPG-------TKKEDI-----LPALKRVQAGHlidAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVAL 159
|
170 180
....*....|....*....|..
gi 738450152 187 REIIQSLKQQ-GKTIFFNSHIL 207
Cdd:PRK09544 160 YDLIDQLRRElDCAVLMVSHDL 181
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
42-244 |
2.80e-18 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 82.91 E-value: 2.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 42 GETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPENAYYYDYLTGWEfLQLIG-----G 113
Cdd:PRK10575 37 GKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwssKAFARKVAYLPQQLPAAEGMTVRE-LVAIGrypwhG 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 114 IFQILSSVQKKRIPELLDLVGLdrKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL 193
Cdd:PRK10575 116 ALGRFGAADREKVEEAISLVGL--KPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRL 193
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 738450152 194 KQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILgRADVYQVI 244
Cdd:PRK10575 194 SQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELM-RGETLEQI 244
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
28-196 |
2.86e-18 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 85.56 E-value: 2.86e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 28 KIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQ----RIGYLPE----NayYY 99
Cdd:NF033858 13 KTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARHRRavcpRIAYMPQglgkN--LY 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 100 DYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGL----DRKtAQKkqlrqYSKGMMQRIGIAQALINDPELVFFDEPM 175
Cdd:NF033858 91 PTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLapfaDRP-AGK-----LSGGMKQKLGLCCALIHDPDLLILDEPT 164
|
170 180
....*....|....*....|.
gi 738450152 176 SGLDPIGRYQVREIIQSLKQQ 196
Cdd:NF033858 165 TGVDPLSRRQFWELIDRIRAE 185
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
32-242 |
3.22e-18 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 84.88 E-value: 3.22e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLlgiVR---PTSGRALILGQPIGDRS----------VRQRI----GYLPE 94
Cdd:PRK11160 356 LKGLSLQIKAGEKVALLGRTGCGKSTLLQLL---TRawdPQQGEILLNGQPIADYSeaalrqaisvVSQRVhlfsATLRD 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 95 NayyydyltgwefLQLIggifqiLSSVQKKRIPELLDLVGLDRKTAQKKQL--------RQYSKGMMQRIGIAQALINDP 166
Cdd:PRK11160 433 N------------LLLA------APNASDEALIEVLQQVGLEKLLEDDKGLnawlgeggRQLSGGEQRRLGIARALLHDA 494
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 167 ELVFFDEPMSGLDpigRYQVREIIQSLKQ--QGKTIFFNSHILSDVEQIcDRIALLARGELLCVGSLDQILGRADVYQ 242
Cdd:PRK11160 495 PLLLLDEPTEGLD---AETERQILELLAEhaQNKTVLMITHRLTGLEQF-DRICVMDNGQIIEQGTHQELLAQQGRYY 568
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
32-241 |
3.60e-18 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 81.89 E-value: 3.60e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPE------NAYYYDYL 102
Cdd:cd03253 17 LKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREvtlDSLRRAIGVVPQdtvlfnDTIGYNIR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 103 TGweflQLIGGIFQILSSVQKKRI-------PELLDLVGLDRKTaqkkqlrQYSKGMMQRIGIAQALINDPELVFFDEPM 175
Cdd:cd03253 97 YG----RPDATDEEVIEAAKAAQIhdkimrfPDGYDTIVGERGL-------KLSGGEKQRVAIARAILKNPPILLLDEAT 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 176 SGLDPIGRyqvREIIQSLKQ--QGKTIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQILGRADVY 241
Cdd:cd03253 166 SALDTHTE---REIQAALRDvsKGRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTHEELLAKGGLY 229
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
36-254 |
4.42e-18 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 81.81 E-value: 4.42e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 36 TLIVHEGETFGLLGPNGAGKTTLLKTLLGIVrPTSGRALILGQPIGDRSV----RQRiGYLPENAYYYDYLTGWEFLQLi 111
Cdd:COG4138 16 SAQVNAGELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLNGRPLSDWSAaelaRHR-AYLSQQQSPPFAMPVFQYLAL- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 112 GGIFQILSSVQKKRIPELLDLVGLDRKTAqkKQLRQYSKGMMQRIGIAQAL------IN-DPELVFFDEPMSGLDPIGRY 184
Cdd:COG4138 93 HQPAGASSEAVEQLLAQLAEALGLEDKLS--RPLTQLSGGEWQRVRLAAVLlqvwptINpEGQLLLLDEPMNSLDVAQQA 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 185 QVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL---GRADVYQV---IVQGGGEEQLQ 254
Cdd:COG4138 171 ALDRLLRELCQQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMtpeNLSEVFGVkfrRLEVEGHRWLI 246
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
34-240 |
5.61e-18 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 81.57 E-value: 5.61e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 34 NCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI----GDRSVRQRIGYLPENAYYYDYLTGWEFL- 108
Cdd:PRK11300 23 NVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIeglpGHQIARMGVVRTFQHVRLFREMTVIENLl 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 ---------QLIGGIFQILSSVQKK-----RIPELLDLVGLdRKTAQkKQLRQYSKGMMQRIGIAQALINDPELVFFDEP 174
Cdd:PRK11300 103 vaqhqqlktGLFSGLLKTPAFRRAEsealdRAATWLERVGL-LEHAN-RQAGNLAYGQQRRLEIARCMVTQPEILMLDEP 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 738450152 175 MSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADV 240
Cdd:PRK11300 181 AAGLNPKETKELDELIAELRNEhNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIRNNPDV 247
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
26-229 |
7.72e-18 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 80.88 E-value: 7.72e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 26 NKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGI--VRPTSGRALILGQPIGDRSV--RQRIG------YLPE- 94
Cdd:COG0396 12 GKEI--LKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHpkYEVTSGSILLDGEDILELSPdeRARAGiflafqYPVEi 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 95 ----NAYyydyltgweFLQL-IGGIFQILSSVQK--KRIPELLDLVGLDrktaqKKQLRQY-----SKGMMQRIGIAQAL 162
Cdd:COG0396 90 pgvsVSN---------FLRTaLNARRGEELSAREflKLLKEKMKELGLD-----EDFLDRYvnegfSGGEKKRNEILQML 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 738450152 163 INDPELVFFDEPMSGLDpIGRYQ-VREIIQSLKQQGKTIFFNSH---ILSDVEqiCDRIALLARGELLCVG 229
Cdd:COG0396 156 LLEPKLAILDETDSGLD-IDALRiVAEGVNKLRSPDRGILIITHyqrILDYIK--PDFVHVLVDGRIVKSG 223
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
8-246 |
1.01e-17 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 80.97 E-value: 1.01e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 8 TVLETLNLqkTYRTGfwlNKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQ 87
Cdd:PRK13548 1 AMLEARNL--SVRLG---GRTL--LDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 88 ---RIGYLPENAyyydyltgweflQL-----------IGGIFQILSSVQKKRIP----ELLDLVGL-DRktaqkkQLRQY 148
Cdd:PRK13548 74 larRRAVLPQHS------------SLsfpftveevvaMGRAPHGLSRAEDDALVaaalAQVDLAHLaGR------DYPQL 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 149 SKGMMQRIGIAQALI------NDPELVFFDEPMSGLDPigRYQ--VREIIQSL-KQQGKTIFFnshILSDVE---QICDR 216
Cdd:PRK13548 136 SGGEQQRVQLARVLAqlwepdGPPRWLLLDEPTSALDL--AHQhhVLRLARQLaHERGLAVIV---VLHDLNlaaRYADR 210
|
250 260 270
....*....|....*....|....*....|....*
gi 738450152 217 IALLARGELLCVGSLDQILGRA---DVYQ--VIVQ 246
Cdd:PRK13548 211 IVLLHQGRLVADGTPAEVLTPEtlrRVYGadVLVQ 245
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
3-258 |
1.30e-17 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 82.91 E-value: 1.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 3 NTSRQTVLETLNLQKtyrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD 82
Cdd:PRK09700 259 NLAHETVFEVRNVTS---------RDRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISP 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 83 RS----VRQRIGYLPENAYYYDYLTGWEFLQLIGgifqILSSVQKKRIPELLDLVG--LDRKTAQKKQ------------ 144
Cdd:PRK09700 330 RSpldaVKKGMAYITESRRDNGFFPNFSIAQNMA----ISRSLKDGGYKGAMGLFHevDEQRTAENQRellalkchsvnq 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 145 -LRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIAllarg 223
Cdd:PRK09700 406 nITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSELPEIITVCDRIA----- 480
|
250 260 270
....*....|....*....|....*....|....*
gi 738450152 224 eLLCVGSLDQILGRADVYQvivqgggEEQLQQWLL 258
Cdd:PRK09700 481 -VFCEGRLTQILTNRDDMS-------EEEIMAWAL 507
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
32-227 |
1.45e-17 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 82.76 E-value: 1.45e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIvRPTS--------GRALILGQPIGDrsVRQRIGYLpENAYYYDY-- 101
Cdd:PRK10938 276 LHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGD-HPQGysndltlfGRRRGSGETIWD--IKKHIGYV-SSSLHLDYrv 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 102 --------LTGweFLQLIGgIFQILSSVQKKRIPELLDLVGLDRKTAqKKQLRQYSKGMMQRIGIAQALINDPELVFFDE 173
Cdd:PRK10938 352 stsvrnviLSG--FFDSIG-IYQAVSDRQQKLAQQWLDILGIDKRTA-DAPFHSLSWGQQRLALIVRALVKHPTLLILDE 427
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 174 PMSGLDPIGRYQVREIIQSLKQQGKT-IFFNSHILSDVEQ-ICDRIALLARGELLC 227
Cdd:PRK10938 428 PLQGLDPLNRQLVRRFVDVLISEGETqLLFVSHHAEDAPAcITHRLEFVPDGDIYR 483
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
23-260 |
1.68e-17 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 82.63 E-value: 1.68e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 23 FWLNKKIE---SLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPigdrsvrqriGYLPENAYYY 99
Cdd:PRK13545 28 FFRSKDGEyhyALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSA----------ALIAISSGLN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 100 DYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKTAQKkqLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLD 179
Cdd:PRK13545 98 GQLTGIENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQP--VKTYSSGMKSRLGFAISVHINPDILVIDEALSVGD 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 180 PIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIlgrADVYQVIVQGGG---------- 249
Cdd:PRK13545 176 QTFTKKCLDKMNEFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEV---VDHYDEFLKKYNqmsveerkdf 252
|
250
....*....|..
gi 738450152 250 -EEQLQQWLLGL 260
Cdd:PRK13545 253 rEEQISQFQHGL 264
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
26-234 |
1.82e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 80.90 E-value: 1.82e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 26 NKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS----VRQRIGYL---PENayy 98
Cdd:PRK13633 20 STEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEEnlwdIRNKAGMVfqnPDN--- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 99 ydyltgweflQLIGGIFQ-----------ILSSVQKKRIPELLDLVGLDRKTAQKKQLrqYSKGMMQRIGIAQALINDPE 167
Cdd:PRK13633 97 ----------QIVATIVEedvafgpenlgIPPEEIRERVDESLKKVGMYEYRRHAPHL--LSGGQKQRVAIAGILAMRPE 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 168 LVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQI 234
Cdd:PRK13633 165 CIIFDEPTAMLDPSGRREVVNTIKELnKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEI 231
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
2-294 |
2.00e-17 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 82.41 E-value: 2.00e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 2 TNTSRQTVLETLNLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIG 81
Cdd:PRK15439 4 SDTTAPPLLCARSISKQY-------SGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 82 DRSvrqrigylPENAYYYD-YLTGWEFLqliggIFQILSSvqKKRIpelldLVGLDRKTAQKKQLRQYSKGM-------- 152
Cdd:PRK15439 77 RLT--------PAKAHQLGiYLVPQEPL-----LFPNLSV--KENI-----LFGLPKRQASMQKMKQLLAALgcqldlds 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 153 ---------MQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARG 223
Cdd:PRK15439 137 sagslevadRQIVEILRGLMRDSRILILDEPTASLTPAETERLFSRIRELLAQGVGIVFISHKLPEIRQLADRISVMRDG 216
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 738450152 224 ELLCVGSLDQiLGRADVYQVIVQGGGEEQL---QQWLLGLhwrDNCWHGQLQGEPDAFLAALSSMDVRLISLNL 294
Cdd:PRK15439 217 TIALSGKTAD-LSTDDIIQAITPAAREKSLsasQKLWLEL---PGNRRQQAAGAPVLTVEDLTGEGFRNISLEV 286
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
10-226 |
7.16e-17 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 80.92 E-value: 7.16e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRTGfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD------- 82
Cdd:PRK10535 5 LELKDIRRSYPSG---EEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATldadala 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 83 RSVRQRIGYLPENAYYYDYLTGWEFLQlIGGIFQILSSVQKK-RIPELLDLVGL-DRKTAQKKQLrqySKGMMQRIGIAQ 160
Cdd:PRK10535 82 QLRREHFGFIFQRYHLLSHLTAAQNVE-VPAVYAGLERKQRLlRAQELLQRLGLeDRVEYQPSQL---SGGQQQRVSIAR 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 161 ALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHIlSDVEQICDRIALLARGELL 226
Cdd:PRK10535 158 ALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHD-PQVAAQAERVIEIRDGEIV 222
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
32-234 |
7.97e-17 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 80.90 E-value: 7.97e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRpTSGRALILGQPIGDRSVRQRIGYLPE--------NAYYYDYLT 103
Cdd:PRK15134 302 VKNISFTLRPGETLGLVGESGSGKSTTGLALLRLIN-SQGEIWFDGQPLHNLNRRQLLPVRHRiqvvfqdpNSSLNPRLN 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 104 gweFLQLIGGIFQI----LSSVQKK-RIPELLDLVGLDRKTAQKKQlRQYSKGMMQRIGIAQALINDPELVFFDEPMSGL 178
Cdd:PRK15134 381 ---VLQIIEEGLRVhqptLSAAQREqQVIAVMEEVGLDPETRHRYP-AEFSGGQRQRIAIARALILKPSLIILDEPTSSL 456
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 738450152 179 DPIGRYQVREIIQSLKQQGKTIF-FNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:PRK15134 457 DKTVQAQILALLKSLQQKHQLAYlFISHDLHVVRALCHQVIVLRQGEVVEQGDCERV 513
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
11-235 |
9.02e-17 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 78.55 E-value: 9.02e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 11 ETLNLQKTYrtgFWLNKKiESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVR------PTSGRALILGQPI---G 81
Cdd:PRK14246 9 DVFNISRLY---LYINDK-AILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEiydskiKVDGKVLYFGKDIfqiD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 82 DRSVRQRIGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRI-PELLDLVGL-----DRKTAQKKQLrqySKGMMQR 155
Cdd:PRK14246 85 AIKLRKEVGMVFQQPNPFPHLSIYDNIAYPLKSHGIKEKREIKKIvEECLRKVGLwkevyDRLNSPASQL---SGGQQQR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 156 IGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQgKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL 235
Cdd:PRK14246 162 LTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNE-IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIF 240
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
26-242 |
9.61e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 79.12 E-value: 9.61e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 26 NKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQRIGYLPENAYYYDYLtgw 105
Cdd:PRK13631 36 ENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIYIGDKKNNHELITNPYSKKIKNFK--- 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 106 EFLQLIGGIFQ-------------------ILSSVQKKRIPEL----LDLVGLDRKTAQKKQLrQYSKGMMQRIGIAQAL 162
Cdd:PRK13631 113 ELRRRVSMVFQfpeyqlfkdtiekdimfgpVALGVKKSEAKKLakfyLNKMGLDDSYLERSPF-GLSGGQKRRVAIAGIL 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 163 INDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADVYQ 242
Cdd:PRK13631 192 AIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIFTDQHIIN 271
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
32-225 |
2.00e-16 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 79.34 E-value: 2.00e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGqpigdrsvRQRIGYLPENAYYYDYLTGWEFL--- 108
Cdd:COG0488 14 LDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPK--------GLRIGYLPQEPPLDDDLTVLDTVldg 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 -----QLIGGIFQI-------------LSSVQKK-----------RIPELLDLVGLDRKTAQKKqLRQYSKGMMQRIGIA 159
Cdd:COG0488 86 daelrALEAELEELeaklaepdedlerLAELQEEfealggweaeaRAEEILSGLGFPEEDLDRP-VSELSGGWRRRVALA 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 160 QALINDPELVFFDEPMSGLDpigryqvreiIQS-------LKQQGKTIFFNSHilsDVE---QICDRIALLARGEL 225
Cdd:COG0488 165 RALLSEPDLLLLDEPTNHLD----------LESiewleefLKNYPGTVLVVSH---DRYfldRVATRILELDRGKL 227
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
29-236 |
2.21e-16 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 79.39 E-value: 2.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 29 IESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS------------------VRQR-- 88
Cdd:PRK10982 11 VKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSskealengismvhqelnlVLQRsv 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 -----IGYLPENAYYYDYLTGWEflqliggifqilssvQKKRIPELLDLvgldrKTAQKKQLRQYSKGMMQRIGIAQALI 163
Cdd:PRK10982 91 mdnmwLGRYPTKGMFVDQDKMYR---------------DTKAIFDELDI-----DIDPRAKVATLSVSQMQMIEIAKAFS 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 164 NDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSL-----DQILG 236
Cdd:PRK10982 151 YNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQWIATQPLagltmDKIIA 228
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
31-239 |
2.32e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 77.46 E-value: 2.32e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 31 SLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSV---RQRIGYL---PENayyydyltg 104
Cdd:PRK13650 22 TLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVwdiRHKIGMVfqnPDN--------- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 105 weflQLIGGIFQ-----------ILSSVQKKRIPELLDLVGL-DRKTAQKKQLrqySKGMMQRIGIAQALINDPELVFFD 172
Cdd:PRK13650 93 ----QFVGATVEddvafglenkgIPHEEMKERVNEALELVGMqDFKEREPARL---SGGQKQRVAIAGAVAMRPKIIILD 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 173 EPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVeQICDRIALLARGELLCVGSLDQILGRAD 239
Cdd:PRK13650 166 EATSMLDPEGRLELIKTIKGIRDDyQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPRELFSRGN 232
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
32-233 |
2.95e-16 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 79.15 E-value: 2.95e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTS--GRALILGQPIGdRSVRQRIGYLPENAYYYDYLTGWEFLQ 109
Cdd:PLN03211 84 LNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANNRKPT-KQILKRTGFVTQDDILYPHLTVRETLV 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 110 LIG--GIFQILSSVQKKRIPEL----LDLVGLDRKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGR 183
Cdd:PLN03211 163 FCSllRLPKSLTKQEKILVAESviseLGLTKCENTIIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAA 242
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 738450152 184 YQVREIIQSLKQQGKTIFFNSHILSD-VEQICDRIALLARGELLCVGSLDQ 233
Cdd:PLN03211 243 YRLVLTLGSLAQKGKTIVTSMHQPSSrVYQMFDSVLVLSEGRCLFFGKGSD 293
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
5-244 |
3.05e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 77.36 E-value: 3.05e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 5 SRQTVLETLNLQKTYRTGFwlnkKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALI--LGQPIGD 82
Cdd:PRK13645 4 SKDIILDNVSYTYAKKTPF----EFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVgdYAIPANL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 83 RSV------RQRIGYL---PENAYYYDYLTGweflQLIGGIFQILSSVQK--KRIPELLDLVGLDRKTAQKKQLrQYSKG 151
Cdd:PRK13645 80 KKIkevkrlRKEIGLVfqfPEYQLFQETIEK----DIAFGPVNLGENKQEayKKVPELLKLVQLPEDYVKRSPF-ELSGG 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 152 MMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGS 230
Cdd:PRK13645 155 QKRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLnKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGS 234
|
250
....*....|....
gi 738450152 231 LDQILGRADVYQVI 244
Cdd:PRK13645 235 PFEIFSNQELLTKI 248
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-234 |
3.20e-16 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 76.61 E-value: 3.20e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 1 MTNTSR--QTVLETLNLqktyrtGFWLNKKiESLKNCTLIVHEGETFGLLGPNGAGKTTLLKT------LLGIVRpTSGR 72
Cdd:COG1117 1 MTAPAStlEPKIEVRNL------NVYYGDK-QALKDINLDIPENKVTALIGPSGCGKSTLLRClnrmndLIPGAR-VEGE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 73 ALILGQPIGDRSV-----RQRIGY-------LP----EN-AYyydyltGwefLQLIGgifqILSsvqKKRIPEL----LD 131
Cdd:COG1117 73 ILLDGEDIYDPDVdvvelRRRVGMvfqkpnpFPksiyDNvAY------G---LRLHG----IKS---KSELDEIveesLR 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 132 LVGL-----DRktaqkkqLRQY----SKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQgKTIFF 202
Cdd:COG1117 137 KAALwdevkDR-------LKKSalglSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKD-YTIVI 208
|
250 260 270
....*....|....*....|....*....|..
gi 738450152 203 NSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:COG1117 209 VTHNMQQAARVSDYTAFFYLGELVEFGPTEQI 240
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
26-261 |
3.52e-16 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 78.53 E-value: 3.52e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 26 NKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR----IGYLPEnayyyDY 101
Cdd:COG3845 268 DRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRERrrlgVAYIPE-----DR 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 102 L-TGweflqLIGG--IFQ--ILSSVQKkriPELLDLVGLDRKTAQK--KQL---------------RQYSKGMMQRIGIA 159
Cdd:COG3845 343 LgRG-----LVPDmsVAEnlILGRYRR---PPFSRGGFLDRKAIRAfaEELieefdvrtpgpdtpaRSLSGGNQQKVILA 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 160 QALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELlcVGSLDqilgRAD 239
Cdd:COG3845 415 RELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDAGAAVLLISEDLDEILALSDRIAVMYEGRI--VGEVP----AAE 488
|
250 260
....*....|....*....|..
gi 738450152 240 VyqvivqggGEEQLQQWLLGLH 261
Cdd:COG3845 489 A--------TREEIGLLMAGVK 502
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
32-225 |
3.90e-16 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 75.97 E-value: 3.90e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---------------------RSVRQRIG 90
Cdd:cd03248 30 LQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQyehkylhskvslvgqepvlfaRSLQDNIA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 91 YlpenayyydYLTGWEFLQliggifqILSSVQKKR----IPELLDlvGLDRKTAQKKQlrQYSKGMMQRIGIAQALINDP 166
Cdd:cd03248 110 Y---------GLQSCSFEC-------VKEAAQKAHahsfISELAS--GYDTEVGEKGS--QLSGGQKQRVAIARALIRNP 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 167 ELVFFDEPMSGLDPIGRYQVREIIQSLKQQgKTIFFNSHILSDVEQiCDRIALLARGEL 225
Cdd:cd03248 170 QVLILDEATSALDAESEQQVQQALYDWPER-RTVLVIAHRLSTVER-ADQILVLDGGRI 226
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
32-246 |
4.15e-16 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 76.04 E-value: 4.15e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLP-----------ENAY 97
Cdd:cd03249 19 LKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDlnlRWLRSQIGLVSqepvlfdgtiaENIR 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 98 YYDYLTGWEFLQLIGGIFQILSSVQKkrIPELLD-LVGlDRKTaqkkqlrQYSKGMMQRIGIAQALINDPELVFFDEPMS 176
Cdd:cd03249 99 YGKPDATDEEVEEAAKKANIHDFIMS--LPDGYDtLVG-ERGS-------QLSGGQKQRIAIARALLRNPKILLLDEATS 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 177 GLDPIGRYQVREIIQSLKqQGKTIFFNSHILSDVeQICDRIALLARGELLCVGSLDQILGRADVYQVIVQ 246
Cdd:cd03249 169 ALDAESEKLVQEALDRAM-KGRTTIVIAHRLSTI-RNADLIAVLQNGQVVEQGTHDELMAQKGVYAKLVK 236
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
10-229 |
4.84e-16 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 76.42 E-value: 4.84e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRTGfwlnkkiESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTL-----LGIVRPTSGRALILGQPIGDRS 84
Cdd:PRK14267 5 IETVNLRVYYGSN-------HVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFnrlleLNEEARVEGEVRLFGRNIYSPD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 85 -----VRQRIGYLPENAYYYDYLTGWEFLQLIGGIFQILSSvqKKRIPELLDLVGldRKTAQ----KKQLRQY----SKG 151
Cdd:PRK14267 78 vdpieVRREVGMVFQYPNPFPHLTIYDNVAIGVKLNGLVKS--KKELDERVEWAL--KKAALwdevKDRLNDYpsnlSGG 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 152 MMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQgKTIFFNSHILSDVEQICDRIALLARGELLCVG 229
Cdd:PRK14267 154 QRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKE-YTIVLVTHSPAQAARVSDYVAFLYLGKLIEVG 230
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
4-217 |
1.17e-15 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 77.16 E-value: 1.17e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 4 TSRQTVLETLNLQKTYrTGFWLNkkIESLKnctliVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRAlilgqpigDR 83
Cdd:PRK13409 335 SERETLVEYPDLTKKL-GDFSLE--VEGGE-----IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEV--------DP 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 84 SVrqRIGYLPEnayyY---DY-LTGWEFLQLIGGIFQilSSVQKkriPELLDLVGLDRktAQKKQLRQYSKGMMQRIGIA 159
Cdd:PRK13409 399 EL--KISYKPQ----YikpDYdGTVEDLLRSITDDLG--SSYYK---SEIIKPLQLER--LLDKNVKDLSGGELQRVAIA 465
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 160 QALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRI 217
Cdd:PRK13409 466 ACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIaEEREATALVVDHDIYMIDYISDRL 524
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
31-244 |
1.45e-15 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 75.17 E-value: 1.45e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 31 SLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYL---PENAYY-----Y 99
Cdd:PRK13648 24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDdnfEKLRKHIGIVfqnPDNQFVgsivkY 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 100 DYLTGWEFlqliggiFQILSSVQKKRIPELLDLVG-LDRKTAQKKQLrqySKGMMQRIGIAQALINDPELVFFDEPMSGL 178
Cdd:PRK13648 104 DVAFGLEN-------HAVPYDEMHRRVSEALKQVDmLERADYEPNAL---SGGQKQRVAIAGVLALNPSVIILDEATSML 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 738450152 179 DPIGRYQVREIIQSLKQQGK-TIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQILGRADVYQVI 244
Cdd:PRK13648 174 DPDARQNLLDLVRKVKSEHNiTIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFDHAEELTRI 239
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
7-237 |
1.56e-15 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 77.03 E-value: 1.56e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 7 QTVLETLNLQKTYRTGfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKT----TLLKTLLGIVRPTSGRALILGQPIGD 82
Cdd:COG4172 4 MPLLSVEDLSVAFGQG---GGTVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 83 ------RSVR-QRIGYLpenayyydyltgweF---------LQLIGgiFQI---------LSSVQ-KKRIPELLDLVGLD 136
Cdd:COG4172 81 lserelRRIRgNRIAMI--------------FqepmtslnpLHTIG--KQIaevlrlhrgLSGAAaRARALELLERVGIP 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 137 RktaQKKQLRQY----SKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVE 211
Cdd:COG4172 145 D---PERRLDAYphqlSGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRElGMALLLITHDLGVVR 221
|
250 260
....*....|....*....|....*.
gi 738450152 212 QICDRIALLARGELLCVGSLDQILGR 237
Cdd:COG4172 222 RFADRVAVMRQGEIVEQGPTAELFAA 247
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
42-206 |
2.06e-15 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 73.55 E-value: 2.06e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 42 GETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD-RSVRQR-IGYLPENAYYYDYLTGWEFLQLiggiFQILS 119
Cdd:TIGR01189 26 GEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEqRDEPHEnILYLGHLPGLKPELSALENLHF----WAAIH 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 120 SVQKKRIPELLDLVGLDrkTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKT 199
Cdd:TIGR01189 102 GGAQRTIEDALAAVGLT--GFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVALLAGLLRAHLARGGI 179
|
....*..
gi 738450152 200 IFFNSHI 206
Cdd:TIGR01189 180 VLLTTHQ 186
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
30-205 |
2.21e-15 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 76.25 E-value: 2.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 30 ESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS---VRQRIGYLPENAYYYDyLTGWE 106
Cdd:TIGR02868 349 PVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDqdeVRRRVSVCAQDAHLFD-TTVRE 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 107 FLQLIGG------IFQILSSVQkkripeLLDLV-----GLDRKTAQKKQLrqYSKGMMQRIGIAQALINDPELVFFDEPM 175
Cdd:TIGR02868 428 NLRLARPdatdeeLWAALERVG------LADWLralpdGLDTVLGEGGAR--LSGGERQRLALARALLADAPILLLDEPT 499
|
170 180 190
....*....|....*....|....*....|..
gi 738450152 176 SGLDPIGRyqvREIIQSLKQ--QGKTIFFNSH 205
Cdd:TIGR02868 500 EHLDAETA---DELLEDLLAalSGRTVVLITH 528
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
39-217 |
2.81e-15 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 76.36 E-value: 2.81e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 39 VHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRAlilgqpigDRSVRqrIGYLPEnayyydYLTGweflQLIGGIFQIL 118
Cdd:COG1245 363 IREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEV--------DEDLK--ISYKPQ------YISP----DYDGTVEEFL 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 119 SSVQKKRIP------ELLDLVGLDRktAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQS 192
Cdd:COG1245 423 RSANTDDFGssyyktEIIKPLGLEK--LLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRR 500
|
170 180
....*....|....*....|....*.
gi 738450152 193 L-KQQGKTIFFNSHILSDVEQICDRI 217
Cdd:COG1245 501 FaENRGKTAMVVDHDIYLIDYISDRL 526
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
29-224 |
2.98e-15 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 76.02 E-value: 2.98e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 29 IESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIvRPT---SGRALILGQPIGDRSVR-----------QRIGYLPE 94
Cdd:TIGR02633 14 VKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGV-YPHgtwDGEIYWSGSPLKASNIRdteragiviihQELTLVPE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 95 NAYYYDYLTGWEfLQLIGGIFQILSSVqkKRIPELLDLVGLDrKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEP 174
Cdd:TIGR02633 93 LSVAENIFLGNE-ITLPGGRMAYNAMY--LRAKNLLRELQLD-ADNVTRPVGDYGGGQQQLVEIAKALNKQARLLILDEP 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 738450152 175 MSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGE 224
Cdd:TIGR02633 169 SSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQ 218
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
1-199 |
4.21e-15 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 73.68 E-value: 4.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 1 MTNTSRqTVLETLNLQKTYRTgfwlnkkIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI 80
Cdd:COG4598 1 MTDTAP-PALEVRDLHKSFGD-------LEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 81 gdRSVRQRIGYL-PENayyydyltgWEFLQLI----GGIFQ--------------ILSSVQKKRIP---------ELLDL 132
Cdd:COG4598 73 --RLKPDRDGELvPAD---------RRQLQRIrtrlGMVFQsfnlwshmtvlenvIEAPVHVLGRPkaeaieraeALLAK 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 133 VGL-DRKTAQKKQLrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDP--IGryQVREIIQSLKQQGKT 199
Cdd:COG4598 142 VGLaDKRDAYPAHL---SGGQQQRAAIARALAMEPEVMLFDEPTSALDPelVG--EVLKVMRDLAEEGRT 206
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
14-224 |
7.02e-15 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 73.15 E-value: 7.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRTgfwlnKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTL------LGIVRpTSGRALILGQPIGDRSV-- 85
Cdd:PRK14258 12 NLSFYYDT-----QKI--LEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLnrmnelESEVR-VEGRVEFFNQNIYERRVnl 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 86 ----RQRIGYLP----------ENAYYYDYLTGWEFLQLIGGIFQilSSVQKKripELLDLVgldrKTAQKKQLRQYSKG 151
Cdd:PRK14258 84 nrlrRQVSMVHPkpnlfpmsvyDNVAYGVKIVGWRPKLEIDDIVE--SALKDA---DLWDEI----KHKIHKSALDLSGG 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 738450152 152 MMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGK-TIFFNSHILSDVEQICDRIALLARGE 224
Cdd:PRK14258 155 QQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSElTMVIVSHNLHQVSRLSDFTAFFKGNE 228
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
34-234 |
7.43e-15 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 73.26 E-value: 7.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 34 NCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQ--PIGDRS----VRQRIGYLPENAYYYDYLT---- 103
Cdd:PRK11831 25 NISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGEniPAMSRSrlytVRKRMSMLFQSGALFTDMNvfdn 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 104 -GW---EFLQLIGGIFQilSSVQKKripelLDLVGLdrKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLD 179
Cdd:PRK11831 105 vAYplrEHTQLPAPLLH--STVMMK-----LEAVGL--RGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQD 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 180 PIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:PRK11831 176 PITMGVLVKLISELNSAlGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL 231
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
32-225 |
8.14e-15 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 72.79 E-value: 8.14e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDrsVRQRIGYLPENAYyydyLTGWEflQLI 111
Cdd:PRK11247 28 LNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAE--AREDTRLMFQDAR----LLPWK--KVI 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 112 GGIFQILSSVQKKRIPELLDLVGL-DRKTAQKKQLrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREII 190
Cdd:PRK11247 100 DNVGLGLKGQWRDAALQALAAVGLaDRANEWPAAL---SGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQDLI 176
|
170 180 190
....*....|....*....|....*....|....*.
gi 738450152 191 QSL-KQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK11247 177 ESLwQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
33-229 |
9.81e-15 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 73.91 E-value: 9.81e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 33 KNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR-IGYLPENAYYYDYLTGWE---F- 107
Cdd:PRK11000 20 KDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAERgVGMVFQSYALYPHLSVAEnmsFg 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 108 LQLIG-GIFQILSSVQKkrIPELLDLVGL-DRKtaqKKQLrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQ 185
Cdd:PRK11000 100 LKLAGaKKEEINQRVNQ--VAEVLQLAHLlDRK---PKAL---SGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQ 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 738450152 186 VR-EIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVG 229
Cdd:PRK11000 172 MRiEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVG 216
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
29-224 |
1.01e-14 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 74.27 E-value: 1.01e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 29 IESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI---GDRS--------VRQRIGYLPENAY 97
Cdd:PRK10762 17 VKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVtfnGPKSsqeagigiIHQELNLIPQLTI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 98 YYDYLTGWEFLQLIGGIfqilssvQKKRIPELLD--LVGLDRKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPM 175
Cdd:PRK10762 97 AENIFLGREFVNRFGRI-------DWKKMYAEADklLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEPT 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 738450152 176 SGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGE 224
Cdd:PRK10762 170 DALTDTETESLFRVIRELKSQGRGIVYISHRLKEIFEICDDVTVFRDGQ 218
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
42-235 |
1.03e-14 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 72.27 E-value: 1.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 42 GETFGLLGPNGAGKTTLLKTLLGIVrPTSGRALILGQPIGDRSvrqrigyLPENAYYYDYLTG----------WEFLQLI 111
Cdd:PRK03695 22 GEILHLVGPNGAGKSTLLARMAGLL-PGSGSIQFAGQPLEAWS-------AAELARHRAYLSQqqtppfampvFQYLTLH 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 112 GGIFQILSSVQkKRIPELLDLVGLDRKTAqkKQLRQYSKGMMQRIGIAQAL------IN-DPELVFFDEPMSGLDPIGRY 184
Cdd:PRK03695 94 QPDKTRTEAVA-SALNEVAEALGLDDKLG--RSVNQLSGGEWQRVRLAAVVlqvwpdINpAGQLLLLDEPMNSLDVAQQA 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 738450152 185 QVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL 235
Cdd:PRK03695 171 ALDRLLSELCQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVL 221
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
30-225 |
1.23e-14 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 71.83 E-value: 1.23e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 30 ESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIG---DRSV---RQRIGYLPENAYYYDYLT 103
Cdd:PRK10908 16 QALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITrlkNREVpflRRQIGMIFQDHHLLMDRT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 104 GWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKTaqKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGR 183
Cdd:PRK10908 96 VYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKA--KNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDALS 173
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 738450152 184 YQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK10908 174 EGILRLFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGHL 215
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
14-217 |
1.26e-14 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 69.78 E-value: 1.26e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYrtgfwLNKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRaLILGQPIgdrsvrqRIGYLP 93
Cdd:cd03221 5 NLSKTY-----GGKLL--LKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGI-VTWGSTV-------KIGYFE 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 94 enayyydyltgweflQLIGGifqilssvQKKripelldlvgldrktaqkkqlrqyskgmmqRIGIAQALINDPELVFFDE 173
Cdd:cd03221 70 ---------------QLSGG--------EKM------------------------------RLALAKLLLENPNLLLLDE 96
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 738450152 174 PMSGLDPIGRYQvreIIQSLKQQGKTIFFNSHILSDVEQICDRI 217
Cdd:cd03221 97 PTNHLDLESIEA---LEEALKEYPGTVILVSHDRYFLDQVATKI 137
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
14-226 |
1.56e-14 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 71.37 E-value: 1.56e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRTGFWLnkkieSLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI---GDRSVRQRIG 90
Cdd:cd03244 7 NVSLRYRPNLPP-----VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDIskiGLHDLRSRIS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 91 YLP-----------ENAYYYDYLTGWEflqliggIFQILSSVQKKRI----PELLDLVGLDRKTaqkkqlrQYSKGMMQR 155
Cdd:cd03244 82 IIPqdpvlfsgtirSNLDPFGEYSDEE-------LWQALERVGLKEFveslPGGLDTVVEEGGE-------NLSVGQRQL 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 738450152 156 IGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSlKQQGKTIFFNSHILSDVEQiCDRIALLARGELL 226
Cdd:cd03244 148 LCLARALLRKSKILVLDEATASVDPETDALIQKTIRE-AFKDCTVLTIAHRLDTIID-SDRILVLDKGRVV 216
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
7-234 |
2.18e-14 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 71.73 E-value: 2.18e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 7 QTVLETLNLQKTYrtgfwlNKKiESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLlgivrptsGRaliLGQPIGDRSVR 86
Cdd:PRK14239 3 EPILQVSDLSVYY------NKK-KALNSVSLDFYPNEITALIGPSGSGKSTLLRSI--------NR---MNDLNPEVTIT 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 87 QRIGYLPENAYYYDYLTgWEFLQLIGGIFQ--------ILSSV-QKKRIPELLDLVGLDRktAQKKQLRQ---------- 147
Cdd:PRK14239 65 GSIVYNGHNIYSPRTDT-VDLRKEIGMVFQqpnpfpmsIYENVvYGLRLKGIKDKQVLDE--AVEKSLKGasiwdevkdr 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 148 -------YSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQgKTIFFNSHILSDVEQICDRIALL 220
Cdd:PRK14239 142 lhdsalgLSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDD-YTMLLVTRSMQQASRISDRTGFF 220
|
250
....*....|....
gi 738450152 221 ARGELLCVGSLDQI 234
Cdd:PRK14239 221 LDGDLIEYNDTKQM 234
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
29-237 |
2.88e-14 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 71.10 E-value: 2.88e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 29 IESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVR-----PTSGRALILGQPIGDRSV---RQRIGYLPENAYYYD 100
Cdd:PRK14247 16 VEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIElypeaRVSGEVYLDGQDIFKMDVielRRRVQMVFQIPNPIP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 101 YLTGWEFLQLIGGIFQILSSVQK--KRIPELLDLVGL-----DRKTAQKKQLrqySKGMMQRIGIAQALINDPELVFFDE 173
Cdd:PRK14247 96 NLSIFENVALGLKLNRLVKSKKElqERVRWALEKAQLwdevkDRLDAPAGKL---SGGQQQRLCIARALAFQPEVLLADE 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 738450152 174 PMSGLDPIGRYQVREIIQSLKQQgKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGR 237
Cdd:PRK14247 173 PTANLDPENTAKIESLFLELKKD-MTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTN 235
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
32-224 |
3.28e-14 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 72.65 E-value: 3.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGiVRPT---SGRALILGQPIGDRSVR-----------QRIGYLPENAY 97
Cdd:PRK13549 21 LDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSG-VYPHgtyEGEIIFEGEELQASNIRdteragiaiihQELALVKELSV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 98 YYDYLTGWEFLQliGGIFQILSSVQkkRIPELLDLVGLDRKTAQKkqLRQYSKGMMQRIGIAQALINDPELVFFDEPMSG 177
Cdd:PRK13549 100 LENIFLGNEITP--GGIMDYDAMYL--RAQKLLAQLKLDINPATP--VGNLGLGQQQLVEIAKALNKQARLLILDEPTAS 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 738450152 178 LDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGE 224
Cdd:PRK13549 174 LTESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGR 220
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
27-229 |
4.50e-14 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 72.58 E-value: 4.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 27 KKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD------RSVRQRIGYLPENAYYY- 99
Cdd:PRK10261 335 REVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTlspgklQALRRDIQFIFQDPYASl 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 100 --DYLTGWEFLQ--LIGGIFQilSSVQKKRIPELLDLVGLDRKTAQKKQlRQYSKGMMQRIGIAQALINDPELVFFDEPM 175
Cdd:PRK10261 415 dpRQTVGDSIMEplRVHGLLP--GKAAAARVAWLLERVGLLPEHAWRYP-HEFSGGQRQRICIARALALNPKVIIADEAV 491
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 738450152 176 SGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVG 229
Cdd:PRK10261 492 SALDVSIRGQIINLLLDLQRDfGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
42-219 |
5.10e-14 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 69.44 E-value: 5.10e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 42 GETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDR--SVRQRIGYLPENAYYYDYLTGWE---FLQLIGGIFQ 116
Cdd:cd03231 26 GEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQrdSIARGLLYLGHAPGIKTTLSVLEnlrFWHADHSDEQ 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 117 ILssvqkkripELLDLVGL----DRKTAqkkqlrQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQS 192
Cdd:cd03231 106 VE---------EALARVGLngfeDRPVA------QLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAG 170
|
170 180
....*....|....*....|....*...
gi 738450152 193 LKQQGKTIFFNSHI-LSDVEQICDRIAL 219
Cdd:cd03231 171 HCARGGMVVLTTHQdLGLSEAGARELDL 198
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
39-200 |
6.78e-14 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 69.49 E-value: 6.78e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 39 VHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI--GDRSvrQRIGYLPENAYYYDYLTGWEFLQLIGGifq 116
Cdd:PRK13543 34 VDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTAtrGDRS--RFMAYLGHLPGLKADLSTLENLHFLCG--- 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 117 iLSSVQKKRIP-ELLDLVGLdrkTAQKKQL-RQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQS-L 193
Cdd:PRK13543 109 -LHGRRAKQMPgSALAIVGL---AGYEDTLvRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGITLVNRMISAhL 184
|
....*..
gi 738450152 194 KQQGKTI 200
Cdd:PRK13543 185 RGGGAAL 191
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
36-235 |
8.87e-14 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 69.61 E-value: 8.87e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 36 TLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQR-IGYLPENAYYYDYLTGWeflQLIG-G 113
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSRRpVSMLFQENNLFSHLTVA---QNIGlG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 114 IFQ--ILSSVQKKRIPELLDLVG----LDRKTAqkkqlrQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRyqvR 187
Cdd:PRK10771 96 LNPglKLNAAQREKLHAIARQMGiedlLARLPG------QLSGGQRQRVALARCLVREQPILLLDEPFSALDPALR---Q 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 738450152 188 EIIQSLKQ----QGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL 235
Cdd:PRK10771 167 EMLTLVSQvcqeRQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELL 218
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
30-237 |
1.96e-13 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 70.60 E-value: 1.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 30 ESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGI--VRPTSGRALI----------------LGQPI---GDRSVRQR 88
Cdd:TIGR03269 14 EVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRIIYhvalcekcgyverpskVGEPCpvcGGTLEPEE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 IGYL-PENAYYYDyltgweFLQLIGGIFQ----------ILSSVQK-------------KRIPELLDLVGLDRKTAQKKq 144
Cdd:TIGR03269 94 VDFWnLSDKLRRR------IRKRIAIMLQrtfalygddtVLDNVLEaleeigyegkeavGRAVDLIEMVQLSHRITHIA- 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 145 lRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVRE-IIQSLKQQGKTIFFNSHILSDVEQICDRIALLARG 223
Cdd:TIGR03269 167 -RDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNaLEEAVKASGISMVLTSHWPEVIEDLSDKAIWLENG 245
|
250
....*....|....
gi 738450152 224 ELLCVGSLDQILGR 237
Cdd:TIGR03269 246 EIKEEGTPDEVVAV 259
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
42-237 |
2.89e-13 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 69.99 E-value: 2.89e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 42 GETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPENAyyydyltgweflqligGIFQ-- 116
Cdd:PRK13657 361 GQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTvtrASLRRNIAVVFQDA----------------GLFNrs 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 117 ILSSVQKKR-------------IPELLDLV-----GLDrkTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGL 178
Cdd:PRK13657 425 IEDNIRVGRpdatdeemraaaeRAQAHDFIerkpdGYD--TVVGERGRQLSGGERQRLAIARALLKDPPILILDEATSAL 502
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 179 DPIGRYQVREIIQSLKqQGKTIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQILGR 237
Cdd:PRK13657 503 DVETEAKVKAALDELM-KGRTTFIIAHRLSTVRN-ADRILVFDNGRVVESGSFDELVAR 559
|
|
| type_I_sec_HlyB |
TIGR01846 |
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ... |
30-241 |
2.97e-13 |
|
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273831 [Multi-domain] Cd Length: 694 Bit Score: 70.16 E-value: 2.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 30 ESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIG---DRSVRQRIGY-LPENAYYYDyltgw 105
Cdd:TIGR01846 471 EVLSNLNLDIKPGEFIGIVGPSGSGKSTLTKLLQRLYTPQHGQVLVDGVDLAiadPAWLRRQMGVvLQENVLFSR----- 545
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 106 eflQLIGGIFQILSSVQKKRIPELLDLVG-LDRKTAQKKQLRQ--------YSKGMMQRIGIAQALINDPELVFFDEPMS 176
Cdd:TIGR01846 546 ---SIRDNIALCNPGAPFEHVIHAAKLAGaHDFISELPQGYNTevgekganLSGGQRQRIAIARALVGNPRILIFDEATS 622
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 177 GLDpigrYQVREIIQSLKQ---QGKTIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQILGRADVY 241
Cdd:TIGR01846 623 ALD----YESEALIMRNMReicRGRTVIIIAHRLSTVRA-CDRIIVLEKGQIAESGRHEELLALQGLY 685
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
28-244 |
3.32e-13 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 68.67 E-value: 3.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 28 KIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTS---GRALILGQPIGDRS---VRQRIGYL---PENayy 98
Cdd:PRK13640 19 KKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDnpnSKITVDGITLTAKTvwdIREKVGIVfqnPDN--- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 99 ydyltgweflQLIGGIF-----------QILSSVQKKRIPELLDLVG-LDRKTAQKKQLrqySKGMMQRIGIAQALINDP 166
Cdd:PRK13640 96 ----------QFVGATVgddvafglenrAVPRPEMIKIVRDVLADVGmLDYIDSEPANL---SGGQKQRVAIAGILAVEP 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 167 ELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQILGRADVYQVI 244
Cdd:PRK13640 163 KIIILDESTSMLDPAGKEQILKLIRKLkKKNNLTVISITHDIDEANM-ADQVLVLDDGKLLAQGSPVEIFSKVEMLKEI 240
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
38-220 |
3.32e-13 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 68.16 E-value: 3.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 38 IVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRalILGQPIGDRSVRQRIGYLPENaYYYDYLTGW-------EFLQL 110
Cdd:cd03236 22 VPREGQVLGLVGPNGIGKSTALKILAGKLKPNLGK--FDDPPDWDEILDEFRGSELQN-YFTKLLEGDvkvivkpQYVDL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 111 I-----GGIFQILSSV----QKKRIPELLDLVG-LDRKtaqkkqLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDP 180
Cdd:cd03236 99 IpkavkGKVGELLKKKdergKLDELVDQLELRHvLDRN------IDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDI 172
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 738450152 181 IGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALL 220
Cdd:cd03236 173 KQRLNAARLIRELAEDDNYVLVVEHDLAVLDYLSDYIHCL 212
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
47-235 |
7.20e-13 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 67.43 E-value: 7.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 47 LLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVrqrigylpenayyYDYLTGWEFLQLIGGIFQ---------- 116
Cdd:PRK14271 52 LMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVLLGGRSI-------------FNYRDVLEFRRRVGMLFQrpnpfpmsim 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 117 --ILSSVQKKRIPELLDLVGLDRK--------TAQKKQLR----QYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIG 182
Cdd:PRK14271 119 dnVLAGVRAHKLVPRKEFRGVAQArltevglwDAVKDRLSdspfRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTT 198
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 738450152 183 RYQVREIIQSLKQQgKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQIL 235
Cdd:PRK14271 199 TEKIEEFIRSLADR-LTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLF 250
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
2-218 |
7.96e-13 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 67.11 E-value: 7.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 2 TNTSRQTVLETLNLQKTYrtGFWLnkkieSLKNCTLIVHEGETFGLLGPNGAGKTTLLKT------LLGIVRpTSGRALI 75
Cdd:PRK14243 3 TLNGTETVLRTENLNVYY--GSFL-----AVKNVWLDIPKNQITAFIGPSGCGKSTILRCfnrlndLIPGFR-VEGKVTF 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 76 LGQPIGDR-----SVRQRIGYL-----PENAYYYDYLTgweFLQLIGGIFQILSSVQKK--RIPELLDLVgldrktaqKK 143
Cdd:PRK14243 75 HGKNLYAPdvdpvEVRRRIGMVfqkpnPFPKSIYDNIA---YGARINGYKGDMDELVERslRQAALWDEV--------KD 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 144 QLRQ----YSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQgKTIFFNSHILSDVEQICDRIA 218
Cdd:PRK14243 144 KLKQsglsLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQ-YTIIIVTHNMQQAARVSDMTA 221
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
37-225 |
9.75e-13 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 67.03 E-value: 9.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 37 LIVHEGETFGLLGPNGAGKTTLLKTLLGI----VRPTSGRALILGQPIGDRSVRQR----IGYLPENAYYyDYLT----G 104
Cdd:PRK10418 24 LTLQRGRVLALVGGSGSGKSLTCAAALGIlpagVRQTAGRVLLDGKPVAPCALRGRkiatIMQNPRSAFN-PLHTmhthA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 105 WEFLQLIGgifqILSSVQkkRIPELLDLVGL-DRKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGR 183
Cdd:PRK10418 103 RETCLALG----KPADDA--TLTAALEAVGLeNAARVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLDVVAQ 176
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 738450152 184 YQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK10418 177 ARILDLLESIvQKRALGMLLVTHDMGVVARLADDVAVMSHGRI 219
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
4-205 |
1.16e-12 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 66.59 E-value: 1.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 4 TSRQTVLETLNLQKTYrtgfwlnKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGivRP----TSGRALILGQP 79
Cdd:CHL00131 2 NKNKPILEIKNLHASV-------NENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG--HPaykiLEGDILFKGES 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 80 IGDRS--VRQRIG-YLpenAYYYDY----LTGWEFLQLiggifqILSSVQKKR-------------IPELLDLVGLDRKT 139
Cdd:CHL00131 73 ILDLEpeERAHLGiFL---AFQYPIeipgVSNADFLRL------AYNSKRKFQglpeldplefleiINEKLKLVGMDPSF 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 140 AQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSH 205
Cdd:CHL00131 144 LSRNVNEGFSGGEKKRNEILQMALLDSELAILDETDSGLDIDALKIIAEGINKLMTSENSIILITH 209
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
14-199 |
1.98e-12 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 66.79 E-value: 1.98e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRTGfwlnkkIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDR---------- 83
Cdd:PRK11650 8 AVRKSYDGK------TQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELepadrdiamv 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 84 ----------SVRQRIGY------LPENayyydyltgweflqliggifQILSSVQK-KRIPELLDLvgLDRKTaqkkqlR 146
Cdd:PRK11650 82 fqnyalyphmSVRENMAYglkirgMPKA--------------------EIEERVAEaARILELEPL--LDRKP------R 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 738450152 147 QYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKT 199
Cdd:PRK11650 134 ELSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKT 186
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
34-205 |
2.16e-12 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 64.83 E-value: 2.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 34 NCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGdrsvRQRIGYLPENAYY------YDYLTGWEF 107
Cdd:PRK13538 19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIR----RQRDEYHQDLLYLghqpgiKTELTALEN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 108 LQliggIFQILSSVQKK-RIPELLDLVGL-DRKTAQKKQLrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQ 185
Cdd:PRK13538 95 LR----FYQRLHGPGDDeALWEALAQVGLaGFEDVPVRQL---SAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVAR 167
|
170 180
....*....|....*....|
gi 738450152 186 VREIIQSLKQQGKTIFFNSH 205
Cdd:PRK13538 168 LEALLAQHAEQGGMVILTTH 187
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
39-234 |
3.59e-12 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 66.79 E-value: 3.59e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 39 VHEGETFGLLGPNGAGKTTLLKTLLGIVrPTSGRALILGQPIGD---RSVRQRIGYLPENAyyydyltgweflQLIGGIF 115
Cdd:PRK11174 373 LPAGQRIALVGPSGAGKTSLLNALLGFL-PYQGSLKINGIELREldpESWRKHLSWVGQNP------------QLPHGTL 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 116 --------------QILSSVQKKRIPELLDLV--GLDrkTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLD 179
Cdd:PRK11174 440 rdnvllgnpdasdeQLQQALENAWVSEFLPLLpqGLD--TPIGDQAAGLSVGQAQRLALARALLQPCQLLLLDEPTASLD 517
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 738450152 180 pigRYQVREIIQSLKQ--QGKTIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQI 234
Cdd:PRK11174 518 ---AHSEQLVMQALNAasRRQTTLMVTHQLEDLAQ-WDQIWVMQDGQIVQQGDYAEL 570
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
7-225 |
5.21e-12 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 64.42 E-value: 5.21e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 7 QTVLETLNLQKTYRTGfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVR 86
Cdd:PRK10584 4 ENIVEVHHLKKSVGQG---EHELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 87 QR-------IGYLPENAYYYDYLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKTaqKKQLRQYSKGMMQRIGIA 159
Cdd:PRK10584 81 ARaklrakhVGFVFQSFMLIPTLNALENVELPALLRGESSRQSRNGAKALLEQLGLGKRL--DHLPAQLSGGEQQRVALA 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 738450152 160 QALINDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHIlSDVEQICDRIALLARGEL 225
Cdd:PRK10584 159 RAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLnREHGTTLILVTHD-LQLAARCDRRLRLVNGQL 224
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
26-225 |
6.02e-12 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 66.00 E-value: 6.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 26 NKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPT-SGRALILGQPIGDR----SVRQRIGYLPENAYYYD 100
Cdd:TIGR02633 270 NPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKPVDIRnpaqAIRAGIAMVPEDRKRHG 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 101 YLTgweflQLIGGIFQILSSVQK----KRIPELLDLVGLDRKTAQKK--------QLRQYSKGMMQRIGIAQALINDPEL 168
Cdd:TIGR02633 350 IVP-----ILGVGKNITLSVLKSfcfkMRIDAAAELQIIGSAIQRLKvktaspflPIGRLSGGNQQKAVLAKMLLTNPRV 424
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 738450152 169 VFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:TIGR02633 425 LILDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGKL 481
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
32-223 |
6.99e-12 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 63.42 E-value: 6.99e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGivRPTS----GRALILGQPIgDRSVRQRIGYLPENAYYYDYLTGWEF 107
Cdd:cd03232 23 LNNISGYVKPGTLTALMGESGAGKTTLLDVLAG--RKTAgvitGEILINGRPL-DKNFQRSTGYVEQQDVHSPNLTVREA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 108 LQLiggifqilSSVqkkripelldLVGLDrkTAQKKqlrqyskgmmqRIGIAQALINDPELVFFDEPMSGLDPIGRYQVR 187
Cdd:cd03232 100 LRF--------SAL----------LRGLS--VEQRK-----------RLTIGVELAAKPSILFLDEPTSGLDSQAAYNIV 148
|
170 180 190
....*....|....*....|....*....|....*..
gi 738450152 188 EIIQSLKQQGKTIFFNSHILS-DVEQICDRIALLARG 223
Cdd:cd03232 149 RFLKKLADSGQAILCTIHQPSaSIFEKFDRLLLLKRG 185
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
9-226 |
1.15e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 63.96 E-value: 1.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYRTgfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSV--- 85
Cdd:PRK13642 4 ILEVENLVFKYEK----ESDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVwnl 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 86 RQRIGYL---PENayyydyltgweflQLIGGIFQ--ILSSVQKKRIPE----------LLDLVGLDRKTAQKKQLrqySK 150
Cdd:PRK13642 80 RRKIGMVfqnPDN-------------QFVGATVEddVAFGMENQGIPReemikrvdeaLLAVNMLDFKTREPARL---SG 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 738450152 151 GMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGK-TIFFNSHILSDVEQiCDRIALLARGELL 226
Cdd:PRK13642 144 GQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQlTVLSITHDLDEAAS-SDRILVMKAGEII 219
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
8-93 |
1.48e-11 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 64.70 E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 8 TVLETLNLQKTYRtgfwlNKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRaLILGQPIgdrsvrq 87
Cdd:COG0488 314 KVLELEGLSKSYG-----DKTL--LDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGT-VKLGETV------- 378
|
....*.
gi 738450152 88 RIGYLP 93
Cdd:COG0488 379 KIGYFD 384
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
1-234 |
1.49e-11 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 64.36 E-value: 1.49e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 1 MTNTSRQTVLETLNLQKTYRTGFWLNKKIESLkNCTLivHEGETFGLLGPNGAGKTTLLKTLLGIVRP---TSGRALILG 77
Cdd:PRK09473 4 LAQQQADALLDVKDLRVTFSTPDGDVTAVNDL-NFSL--RAGETLGIVGESGSGKSQTAFALMGLLAAngrIGGSATFNG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 78 QPIGDrsvrqrigyLPENAYyyDYLTGWEflqlIGGIFQ--ILSSVQKKRIPELLDLV-----GLDRKTA---------- 140
Cdd:PRK09473 81 REILN---------LPEKEL--NKLRAEQ----ISMIFQdpMTSLNPYMRVGEQLMEVlmlhkGMSKAEAfeesvrmlda 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 141 -----QKKQLRQY----SKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKT-IFFNSHILSDV 210
Cdd:PRK09473 146 vkmpeARKRMKMYphefSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVV 225
|
250 260
....*....|....*....|....
gi 738450152 211 EQICDRIALLARGELLCVGSLDQI 234
Cdd:PRK09473 226 AGICDKVLVMYAGRTMEYGNARDV 249
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
33-235 |
1.92e-11 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 63.47 E-value: 1.92e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 33 KNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI---GDRSVRQRIGYLPENAYYYDYLTGWEFLQ 109
Cdd:PRK10253 24 ENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIqhyASKEVARRIGLLAQNATTPGDITVQELVA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 110 LIGGIFQILSSVQKKR----IPELLDLVGLDRKTAQkkQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQ 185
Cdd:PRK10253 104 RGRYPHQPLFTRWRKEdeeaVTKAMQATGITHLADQ--SVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDISHQID 181
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 738450152 186 VREIIQSL-KQQGKTIffnSHILSDVEQIC---DRIALLARGELLCVGSLDQIL 235
Cdd:PRK10253 182 LLELLSELnREKGYTL---AAVLHDLNQACryaSHLIALREGKIVAQGAPKEIV 232
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
38-201 |
2.49e-11 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 64.04 E-value: 2.49e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 38 IVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSG---------------RALILG---QPIGDRSVR-----QRIGYLPE 94
Cdd:COG1245 95 VPKKGKVTGILGPNGIGKSTALKILSGELKPNLGdydeepswdevlkrfRGTELQdyfKKLANGEIKvahkpQYVDLIPK 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 95 nayyydyltgweflQLIGGIFQILSSV-QKKRIPELLDLVGLDrkTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDE 173
Cdd:COG1245 175 --------------VFKGTVRELLEKVdERGKLDELAEKLGLE--NILDRDISELSGGELQRVAIAAALLRDADFYFFDE 238
|
170 180
....*....|....*....|....*...
gi 738450152 174 PMSGLDPIGRYQVREIIQSLKQQGKTIF 201
Cdd:COG1245 239 PSSYLDIYQRLNVARLIRELAEEGKYVL 266
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
38-201 |
2.56e-11 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 64.06 E-value: 2.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 38 IVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTsgraliLGQPIGD---------------------------RSVR--QR 88
Cdd:PRK13409 95 IPKEGKVTGILGPNGIGKTTAVKILSGELIPN------LGDYEEEpswdevlkrfrgtelqnyfkklyngeiKVVHkpQY 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 89 IGYLPEnayyydyltgweflQLIGGIFQILSSV-QKKRIPELLDLVGL----DRKtaqkkqLRQYSKGMMQRIGIAQALI 163
Cdd:PRK13409 169 VDLIPK--------------VFKGKVRELLKKVdERGKLDEVVERLGLenilDRD------ISELSGGELQRVAIAAALL 228
|
170 180 190
....*....|....*....|....*....|....*...
gi 738450152 164 NDPELVFFDEPMSGLDPIGRYQVREIIQSLkQQGKTIF 201
Cdd:PRK13409 229 RDADFYFFDEPTSYLDIRQRLNVARLIREL-AEGKYVL 265
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
42-206 |
2.61e-11 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 61.81 E-value: 2.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 42 GETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQRIGYL-PENAyYYDYLTGWEFLQLIGGIF-QILS 119
Cdd:PRK13539 28 GEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEACHYLgHRNA-MKPALTVAENLEFWAAFLgGEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 120 SvqkkrIPELLDLVGLDRktAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKT 199
Cdd:PRK13539 107 D-----IAAALEAVGLAP--LAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVALFAELIRAHLAQGGI 179
|
....*..
gi 738450152 200 IFFNSHI 206
Cdd:PRK13539 180 VIAATHI 186
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
32-223 |
3.28e-11 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 64.36 E-value: 3.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTL-----LGIVrpTSGRALILGQPIgDRSVRQRIGYLPENAYYYDYLTGWE 106
Cdd:TIGR00956 779 LNNVDGWVKPGTLTALMGASGAGKTTLLNVLaervtTGVI--TGGDRLVNGRPL-DSSFQRSIGYVQQQDLHLPTSTVRE 855
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 107 FLQLIGGIFQIlSSVQKKR----IPELLDLVGLDR-------------KTAQKKqlrqyskgmmqRIGIAQALINDPE-L 168
Cdd:TIGR00956 856 SLRFSAYLRQP-KSVSKSEkmeyVEEVIKLLEMESyadavvgvpgeglNVEQRK-----------RLTIGVELVAKPKlL 923
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 169 VFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILS-DVEQICDRIALLARG 223
Cdd:TIGR00956 924 LFLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSaILFEEFDRLLLLQKG 979
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
32-224 |
3.86e-11 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 61.33 E-value: 3.86e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGqpigdrsvrqRIGYLPENAyyydyltgWeflqLI 111
Cdd:cd03250 21 LKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG----------SIAYVSQEP--------W----IQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 112 GGIFQ--IL--SSVQKKRIPELLDLVGLDRktaqkkQLRQYSKGMM---------------QRIGIAQALINDPELVFFD 172
Cdd:cd03250 79 NGTIRenILfgKPFDEERYEKVIKACALEP------DLEILPDGDLteigekginlsggqkQRISLARAVYSDADIYLLD 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 738450152 173 EPMSGLDP-IGRYQVREIIQSLKQQGKTIFFNSHILSDVEQiCDRIALLARGE 224
Cdd:cd03250 153 DPLSAVDAhVGRHIFENCILGLLLNNKTRILVTHQLQLLPH-ADQIVVLDNGR 204
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
41-217 |
4.11e-11 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 62.04 E-value: 4.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 41 EGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILgqpigdrsvRQRIGYLPEnayyydYLTGweflQLIGGIFQILSS 120
Cdd:cd03237 24 ESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIE---------LDTVSYKPQ------YIKA----DYEGTVRDLLSS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 121 VQKKR------IPELLDLVGLDRKTAQkkQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL- 193
Cdd:cd03237 85 ITKDFythpyfKTEIAKPLQIEQILDR--EVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRFa 162
|
170 180
....*....|....*....|....
gi 738450152 194 KQQGKTIFFNSHILSDVEQICDRI 217
Cdd:cd03237 163 ENNEKTAFVVEHDIIMIDYLADRL 186
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
2-223 |
5.86e-11 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 62.82 E-value: 5.86e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 2 TNTSRQTVLETLNLQktyrtgfwlNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIG 81
Cdd:PRK10982 243 ENKPGEVILEVRNLT---------SLRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKIN 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 82 DRSVRQRIgylpENAY-----------YYDYLTgWEFLQLIGGI------FQILSSVQ-KKRIPELLDlvGLDRKT-AQK 142
Cdd:PRK10982 314 NHNANEAI----NHGFalvteerrstgIYAYLD-IGFNSLISNIrnyknkVGLLDNSRmKSDTQWVID--SMRVKTpGHR 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 143 KQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLAR 222
Cdd:PRK10982 387 TQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRILVMSN 466
|
.
gi 738450152 223 G 223
Cdd:PRK10982 467 G 467
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
26-225 |
1.62e-10 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 61.48 E-value: 1.62e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 26 NKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGiVRP--TSGRALILGQPIGDRS----VRQRIGYLPENAYYY 99
Cdd:PRK13549 272 NPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFG-AYPgrWEGEIFIDGKPVKIRNpqqaIAQGIAMVPEDRKRD 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 100 -----------------DYLTGWEFLQLIGGIFQILSSVQKKRIpelldlvgldrKTAQKKQ-LRQYSKGMMQRIGIAQA 161
Cdd:PRK13549 351 givpvmgvgknitlaalDRFTGGSRIDDAAELKTILESIQRLKV-----------KTASPELaIARLSGGNQQKAVLAKC 419
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 738450152 162 LINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK13549 420 LLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQGVAIIVISSELPEVLGLSDRVLVMHEGKL 483
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
36-225 |
1.98e-10 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 61.47 E-value: 1.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 36 TLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS----VRQRIGYLPENayyydyltgweflQLI 111
Cdd:PRK11288 273 SFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSprdaIRAGIMLCPED-------------RKA 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 112 GGIFQILS-------SVQKKRIPE--LLD-----------LVGLDRKTAQKKQL-RQYSKGMMQRIGIAQALINDPELVF 170
Cdd:PRK11288 340 EGIIPVHSvadniniSARRHHLRAgcLINnrweaenadrfIRSLNIKTPSREQLiMNLSGGNQQKAILGRWLSEDMKVIL 419
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 738450152 171 FDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK11288 420 LDEPTRGIDVGAKHEIYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMREGRI 474
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
19-223 |
2.25e-10 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 59.73 E-value: 2.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 19 YRTGfwlNKKIesLKNCTLIVHEGEtFGLL-GPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS---VRQRIGY--- 91
Cdd:PRK10247 15 YLAG---DAKI--LNNISFSLRAGE-FKLItGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKpeiYRQQVSYcaq 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 92 ---LPENAYYYDYLTGWEFLQliggifqilSSVQKKRIPELLDLVGLDRKTAQKKqLRQYSKGMMQRIGIAQALINDPEL 168
Cdd:PRK10247 89 tptLFGDTVYDNLIFPWQIRN---------QQPDPAIFLDDLERFALPDTILTKN-IAELSGGEKQRISLIRNLQFMPKV 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 169 VFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFFNSHILSDVEQICDRIALLARG 223
Cdd:PRK10247 159 LLLDEITSALDESNKHNVNEIIHRYvREQNIAVLWVTHDKDEINHADKVITLQPHA 214
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
36-224 |
3.42e-10 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 60.20 E-value: 3.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 36 TLIVHEGETFGLLGPNGAGKTTLLKTLLGIV----RPTSGRALILGQPIGDRSVRQR---IGY-------LPENAYYYDY 101
Cdd:PRK15093 27 SMTLTEGEIRGLVGESGSGKSLIAKAICGVTkdnwRVTADRMRFDDIDLLRLSPRERrklVGHnvsmifqEPQSCLDPSE 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 102 LTGWEFLQLI------GGIFQILSSvQKKRIPELLDLVGL-DRKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEP 174
Cdd:PRK15093 107 RVGRQLMQNIpgwtykGRWWQRFGW-RKRRAIELLHRVGIkDHKDAMRSFPYELTEGECQKVMIAIALANQPRLLIADEP 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 738450152 175 MSGLDPIGRYQVREIIQSLKQ-QGKTIFFNSHILSDVEQICDRIALLARGE 224
Cdd:PRK15093 186 TNAMEPTTQAQIFRLLTRLNQnNNTTILLISHDLQMLSQWADKINVLYCGQ 236
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
37-225 |
7.55e-10 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 59.60 E-value: 7.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 37 LIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIgylpeNAYYYDYltgWEFLQLIGG 113
Cdd:PRK10522 344 LTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAeqpEDYRKLF-----SAVFTDF---HLFDQLLGP 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 114 IFQilsSVQKKRIPELLDLVGLDRK-TAQKKQLR--QYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGR---YQvr 187
Cdd:PRK10522 416 EGK---PANPALVEKWLERLKMAHKlELEDGRISnlKLSKGQKKRLALLLALAEERDILLLDEWAADQDPHFRrefYQ-- 490
|
170 180 190
....*....|....*....|....*....|....*...
gi 738450152 188 EIIQSLKQQGKTIFFNSHILSDVEQiCDRIALLARGEL 225
Cdd:PRK10522 491 VLLPLLQEMGKTIFAISHDDHYFIH-ADRLLEMRNGQL 527
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
32-205 |
8.44e-10 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 57.65 E-value: 8.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIG-DRSV-RQRIGYLPENAYYYDYLTGWEflq 109
Cdd:PRK13540 17 LQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKkDLCTyQKQLCFVGHRSGINPYLTLRE--- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 110 liGGIFQILSSVQKKRIPELLDLVGLDRKTAQKKQLrqYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREI 189
Cdd:PRK13540 94 --NCLYDIHFSPGAVGITELCRLFSLEHLIDYPCGL--LSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITK 169
|
170
....*....|....*.
gi 738450152 190 IQSLKQQGKTIFFNSH 205
Cdd:PRK13540 170 IQEHRAKGGAVLLTSH 185
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
39-217 |
1.03e-09 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 56.81 E-value: 1.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 39 VHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRalilgqpigDRSVRQRIGYLPenayyydyltgweflqliggifqil 118
Cdd:cd03222 22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDN---------DEWDGITPVYKP------------------------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 119 ssvqkkripelldlvgldrktaQKKQLrqySKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQG- 197
Cdd:cd03222 68 ----------------------QYIDL---SGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGk 122
|
170 180
....*....|....*....|
gi 738450152 198 KTIFFNSHILSDVEQICDRI 217
Cdd:cd03222 123 KTALVVEHDLAVLDYLSDRI 142
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
32-241 |
1.64e-09 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 58.68 E-value: 1.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPE------NAYYYDYL 102
Cdd:COG5265 374 LKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDvtqASLRAAIGIVPQdtvlfnDTIAYNIA 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 103 TG---------WEFLQLIggifQILSSVQkkRIPELLD-LVG-----LdrktaqkkqlrqySKGMMQRIGIAQALINDPE 167
Cdd:COG5265 454 YGrpdaseeevEAAARAA----QIHDFIE--SLPDGYDtRVGerglkL-------------SGGEKQRVAIARTLLKNPP 514
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 168 LVFFDEPMSGLDPIGRyqvREIIQSLKQ--QGKTIFFNSHILSDVeQICDRIALLARGELLCVGSLDQILGRADVY 241
Cdd:COG5265 515 ILIFDEATSALDSRTE---RAIQAALREvaRGRTTLVIAHRLSTI-VDADEILVLEAGRIVERGTHAELLAQGGLY 586
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
39-179 |
1.95e-09 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 57.24 E-value: 1.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 39 VHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQrigyLPENAYYYDYLTGWEFLQliggifqil 118
Cdd:PRK11701 29 LYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDLYA----LSEAERRRLLRTEWGFVH--------- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 119 ssvQKKR------------IPELLDLVGLD-----RKTAQK-------------KQLRQYSKGMMQRIGIAQALINDPEL 168
Cdd:PRK11701 96 ---QHPRdglrmqvsaggnIGERLMAVGARhygdiRATAGDwlerveidaaridDLPTTFSGGMQQRLQIARNLVTHPRL 172
|
170
....*....|.
gi 738450152 169 VFFDEPMSGLD 179
Cdd:PRK11701 173 VFMDEPTGGLD 183
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
27-234 |
1.99e-09 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 58.33 E-value: 1.99e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 27 KKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALIlGQPIGDRSVRQRIGYLPENAYYYDYLTGWE 106
Cdd:PRK10261 27 QKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQC-DKMLLRRRSRQVIELSEQSAAQMRHVRGAD 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 107 flqlIGGIFQ-ILSSVQK-----KRIPELLDL---VGLDRKTAQKK----QLR-------------QYSKGMMQRIGIAQ 160
Cdd:PRK10261 106 ----MAMIFQePMTSLNPvftvgEQIAESIRLhqgASREEAMVEAKrmldQVRipeaqtilsryphQLSGGMRQRVMIAM 181
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738450152 161 ALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:PRK10261 182 ALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEmSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQI 256
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
10-180 |
2.42e-09 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 57.02 E-value: 2.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 10 LETLNLQKTYRTGFWLNKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRSVRQRI 89
Cdd:COG1101 2 LELKNLSKTFNPGTVNEKRA--LDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 90 GYlpenayyydyltgweflqlIGGIFQ-----------IL----------------SSVQKKRIP---ELLDLVGL---D 136
Cdd:COG1101 80 KY-------------------IGRVFQdpmmgtapsmtIEenlalayrrgkrrglrRGLTKKRRElfrELLATLGLgleN 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 738450152 137 RKTAQKKQLrqySKGmmQRigiaQAL------INDPELVFFDEPMSGLDP 180
Cdd:COG1101 141 RLDTKVGLL---SGG--QR----QALsllmatLTKPKLLLLDEHTAALDP 181
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
32-180 |
5.49e-09 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 57.12 E-value: 5.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGEtfGLL--GPNGAGKTTLLKTLLG--------IVRPTSGRALILGQ----PIGdrSVRQRIGYlPENAy 97
Cdd:COG4178 379 LEDLSLSLKPGE--RLLitGPSGSGKSTLLRAIAGlwpygsgrIARPAGARVLFLPQrpylPLG--TLREALLY-PATA- 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 98 yydyltgweflqliggifqilSSVQKKRIPELLDLVGLDRKTAQKKQLRQYSK----GMMQRIGIAQALINDPELVFFDE 173
Cdd:COG4178 453 ---------------------EAFSDAELREALEAVGLGHLAERLDEEADWDQvlslGEQQRLAFARLLLHKPDWLFLDE 511
|
....*..
gi 738450152 174 PMSGLDP 180
Cdd:COG4178 512 ATSALDE 518
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
24-237 |
5.82e-09 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 57.26 E-value: 5.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 24 WLNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQ----P----IGDRSVRQRI--GYLP 93
Cdd:TIGR00957 646 WARDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGSvayvPqqawIQNDSLRENIlfGKAL 725
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 94 ENAYYYDYLTGWEFLqliggifqilssvqkkriPELLDLVGLDRKTAQKKQLrQYSKGMMQRIGIAQALINDPELVFFDE 173
Cdd:TIGR00957 726 NEKYYQQVLEACALL------------------PDLEILPSGDRTEIGEKGV-NLSGGQKQRVSLARAVYSNADIYLFDD 786
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 174 PMSGLDP-IGRYQVREIIQSLKQ-QGKTIFFNSHILSDVEQIcDRIALLARGELLCVGSLDQILGR 237
Cdd:TIGR00957 787 PLSAVDAhVGKHIFEHVIGPEGVlKNKTRILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQR 851
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
45-234 |
6.75e-09 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 56.42 E-value: 6.75e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 45 FGLlgpNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDrsVRQRIGYLPENayyydyltgweflQLIGGIFQ-------- 116
Cdd:PRK11144 30 FGR---SGAGKTSLINAISGLTRPQKGRIVLNGRVLFD--AEKGICLPPEK-------------RRIGYVFQdarlfphy 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 117 -----ILSSVQKKRIPELLDLVGLdrkTAQKKQLRQY----SKGMMQRIGIAQALINDPELVFFDEPMSGLDpIGRYqvR 187
Cdd:PRK11144 92 kvrgnLRYGMAKSMVAQFDKIVAL---LGIEPLLDRYpgslSGGEKQRVAIGRALLTAPELLLMDEPLASLD-LPRK--R 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 738450152 188 EII---QSLKQQGKT-IFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:PRK11144 166 ELLpylERLAREINIpILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEV 216
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
37-242 |
9.43e-09 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 56.18 E-value: 9.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 37 LIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRAlilgqpigdRSVRQRIGYLpenayyydyltGWEFLQ-LIGGIF 115
Cdd:PRK10938 24 LTLNAGDSWAFVGANGSGKSALARALAGELPLLSGER---------QSQFSHITRL-----------SFEQLQkLVSDEW 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 116 Q---------------------ILSSVQK-KRIPELLDLVG----LDRKtaqkkqLRQYSKGMMQRIGIAQALINDPELV 169
Cdd:PRK10938 84 QrnntdmlspgeddtgrttaeiIQDEVKDpARCEQLAQQFGitalLDRR------FKYLSTGETRKTLLCQALMSEPDLL 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 738450152 170 FFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQILGRADVYQ 242
Cdd:PRK10938 158 ILDEPFDGLDVASRQQLAELLASLHQSGITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEILQQALVAQ 230
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
32-225 |
1.03e-08 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 54.34 E-value: 1.03e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPE-----------NAY 97
Cdd:cd03369 24 LKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTiplEDLRSSLTIIPQdptlfsgtirsNLD 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 98 YYDYLTGWEflqliggIFQILssvqkkRIPElldlVGLDrktaqkkqlrqYSKGMMQRIGIAQALINDPELVFFDEPMSG 177
Cdd:cd03369 104 PFDEYSDEE-------IYGAL------RVSE----GGLN-----------LSQGQRQLLCLARALLKRPRVLVLDEATAS 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 738450152 178 LDPIGRYQVREIIQSLkQQGKTIFFNSHILSDVEQiCDRIALLARGEL 225
Cdd:cd03369 156 IDYATDALIQKTIREE-FTNSTILTIAHRLRTIID-YDKILVMDAGEV 201
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
5-228 |
2.53e-08 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 55.10 E-value: 2.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 5 SRQTVLETLNLQKTYRTGFWLNKKIESLkncTLIVHEGETFGLLGPNGAGKTTllkTLLGIVR--PT------SGRALIL 76
Cdd:PRK15134 1 MTQPLLAIENLSVAFRQQQTVRTVVNDV---SLQIEAGETLALVGESGSGKSV---TALSILRllPSppvvypSGDIRFH 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 77 GQPI---GDRSVRQRIGylpenayyydyltgweflQLIGGIFQ-------ILSSVQKKrIPELLDL-VGLDRKTAQ---- 141
Cdd:PRK15134 75 GESLlhaSEQTLRGVRG------------------NKIAMIFQepmvslnPLHTLEKQ-LYEVLSLhRGMRREAARgeil 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 142 -----------KKQLR----QYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQ-GKTIFFNSH 205
Cdd:PRK15134 136 ncldrvgirqaAKRLTdyphQLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQElNMGLLFITH 215
|
250 260
....*....|....*....|...
gi 738450152 206 ILSDVEQICDRIALLARGEllCV 228
Cdd:PRK15134 216 NLSIVRKLADRVAVMQNGR--CV 236
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
31-255 |
2.55e-08 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 55.37 E-value: 2.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 31 SLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALIlgqpigdrsVRQRIGYLPENAYYYDyLTGWEFLqL 110
Cdd:PLN03232 632 TLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAETSSVV---------IRGSVAYVPQVSWIFN-ATVRENI-L 700
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 111 IGGIFQ---ILSSVQKKRIPELLDLV-GLDRKTAQKKQLrQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQV 186
Cdd:PLN03232 701 FGSDFEserYWRAIDVTALQHDLDLLpGRDLTEIGERGV-NISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQV 779
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 187 REIIQSLKQQGKTIFFNSHILSDVEQIcDRIALLARGELLCVGSLDQILGRADVYQVIVQGGGEEQLQQ 255
Cdd:PLN03232 780 FDSCMKDELKGKTRVLVTNQLHFLPLM-DRIILVSEGMIKEEGTFAELSKSGSLFKKLMENAGKMDATQ 847
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
32-205 |
2.60e-08 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 53.42 E-value: 2.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIV--RPTSGRALILGQPIGDRSVrqrigylpenayyydyltgweflq 109
Cdd:COG2401 46 LRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDVPDNQFGREAS------------------------ 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 110 LIGGIFQILSSVQKKripELLDLVGLDRKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREI 189
Cdd:COG2401 102 LIDAIGRKGDFKDAV---ELLNAVGLSDAVLWLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVARN 178
|
170
....*....|....*..
gi 738450152 190 IQSL-KQQGKTIFFNSH 205
Cdd:COG2401 179 LQKLaRRAGITLVVATH 195
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
32-220 |
2.79e-08 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 54.80 E-value: 2.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGiVRPT---SGRALILGQPIGDRSVR-----------QRIGYLPenay 97
Cdd:NF040905 17 LDDVNLSVREGEIHALCGENGAGKSTLMKVLSG-VYPHgsyEGEILFDGEVCRFKDIRdsealgiviihQELALIP---- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 98 yydYLTGWE--FL---QLIGGIfqILSSVQKKRIPELLDLVGLD-RKTAQKKQLrqySKGMMQRIGIAQALINDPELVFF 171
Cdd:NF040905 92 ---YLSIAEniFLgneRAKRGV--IDWNETNRRARELLAKVGLDeSPDTLVTDI---GVGKQQLVEIAKALSKDVKLLIL 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 738450152 172 DEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALL 220
Cdd:NF040905 164 DEPTAALNEEDSAALLDLLLELKAQGITSIIISHKLNEIRRVADSITVL 212
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
32-242 |
4.22e-08 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 54.03 E-value: 4.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIV--RPTSGRALILGQPIGDRSVRQRIG----YLPENAYYYDyltgw 105
Cdd:NF040905 276 VDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGRSygRNISGTVFKDGKEVDVSTVSDAIDaglaYVTEDRKGYG----- 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 106 efLQLIGGIFQILSSVQKKRIPE--LLDLVGlDRKTAQ--KKQLRQYSKGMMQRIG-----------IAQALINDPELVF 170
Cdd:NF040905 351 --LNLIDDIKRNITLANLGKVSRrgVIDENE-EIKVAEeyRKKMNIKTPSVFQKVGnlsggnqqkvvLSKWLFTDPDVLI 427
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 738450152 171 FDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGELlcVGSLDqilgRADVYQ 242
Cdd:NF040905 428 LDEPTRGIDVGAKYEIYTIINELAAEGKGVIVISSELPELLGMCDRIYVMNEGRI--TGELP----REEASQ 493
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
32-225 |
5.05e-08 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 54.19 E-value: 5.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRaLILGQPIgdrsVRQRIGYLP---ENAYYYDYLTgwEFL 108
Cdd:PRK11147 19 LDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGR-IIYEQDL----IVARLQQDPprnVEGTVYDFVA--EGI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 109 QLIGGIFQI-------------------LSSVQKK-----------RIPELLDLVGLDRKTaqkkQLRQYSKGMMQRIGI 158
Cdd:PRK11147 92 EEQAEYLKRyhdishlvetdpseknlneLAKLQEQldhhnlwqlenRINEVLAQLGLDPDA----ALSSLSGGWLRKAAL 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 738450152 159 AQALINDPELVFFDEPMSGLDPigryqvrEIIQSLKQ-----QGkTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK11147 168 GRALVSNPDVLLLDEPTNHLDI-------ETIEWLEGflktfQG-SIIFISHDRSFIRNMATRIVDLDRGKL 231
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
14-249 |
6.02e-08 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 52.78 E-value: 6.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 14 NLQKTYRtgfwlNKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIG 90
Cdd:COG4604 6 NVSKRYG-----GKVV--LDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATtpsRELAKRLA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 91 YLPENAYYYDYLTgweFLQLIG-GIFQI----LSSVQKKRIPELLDLVGLDrkTAQKKQLRQYSKGMMQRIGIAQALIND 165
Cdd:COG4604 79 ILRQENHINSRLT---VRELVAfGRFPYskgrLTAEDREIIDEAIAYLDLE--DLADRYLDELSGGQRQRAFIAMVLAQD 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 166 PELVFFDEPMSGLDPigrYQVREIIQSLKQ----QGKTIF-------FNSHilsdveqICDRIALLARGELLCVGSLDQI 234
Cdd:COG4604 154 TDYVLLDEPLNNLDM---KHSVQMMKLLRRladeLGKTVVivlhdinFASC-------YADHIVAMKDGRVVAQGTPEEI 223
|
250 260
....*....|....*....|.
gi 738450152 235 LGRA---DVYQV---IVQGGG 249
Cdd:COG4604 224 ITPEvlsDIYDTdieVEEIDG 244
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
39-234 |
7.88e-08 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 52.82 E-value: 7.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 39 VHEGETFGLLGPNGAGKTTLLKTLLGIV----RPTSGRALILG---QPIGDRSVRQRIGylPENAYYY-DYLTGWEFLQL 110
Cdd:PRK11022 30 VKQGEVVGIVGESGSGKSVSSLAIMGLIdypgRVMAEKLEFNGqdlQRISEKERRNLVG--AEVAMIFqDPMTSLNPCYT 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 111 IGgiFQILSSVQ----------KKRIPELLDLVGL-DRKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLD 179
Cdd:PRK11022 108 VG--FQIMEAIKvhqggnkktrRQRAIDLLNQVGIpDPASRLDVYPHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALD 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 180 PIGRYQVREIIQSLKQQ-GKTIFFNSHILSDVEQICDRIALLARGELLCVGSLDQI 234
Cdd:PRK11022 186 VTIQAQIIELLLELQQKeNMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDI 241
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
19-202 |
1.27e-07 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 51.11 E-value: 1.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 19 YRTGFWLNK---------KIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGralilgqpigdrsvrqri 89
Cdd:cd03233 1 ASTLSWRNIsfttgkgrsKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNVS------------------ 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 90 gylPENAYYYDYLTGWEFLQliggIFQ---ILSSVQKKRIPELldLVGLDRKTAQKKQ----LRQYSKGMMQRIGIAQAL 162
Cdd:cd03233 63 ---VEGDIHYNGIPYKEFAE----KYPgeiIYVSEEDVHFPTL--TVRETLDFALRCKgnefVRGISGGERKRVSIAEAL 133
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 738450152 163 INDPELVFFDEPMSGLDPIGRYQVREIIQSL-KQQGKTIFF 202
Cdd:cd03233 134 VSRASVLCWDNSTRGLDSSTALEILKCIRTMaDVLKTTTFV 174
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
31-255 |
1.47e-07 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 52.82 E-value: 1.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 31 SLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILgqpigdrsvRQRIGYLPEnayyydylTGWEFLQL 110
Cdd:PLN03130 632 TLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLGELPPRSDASVVI---------RGTVAYVPQ--------VSWIFNAT 694
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 111 IGGIFQILSSVQKKRIPELLDLVGLDRK---------TAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDP- 180
Cdd:PLN03130 695 VRDNILFGSPFDPERYERAIDVTALQHDldllpggdlTEIGERGVNISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAh 774
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 181 IGRyQVRE--IIQSLKQQGKTIFFNS-HILSDVeqicDRIALLARGELLCVGSLDQILGRADVYQVIVQGGG--EEQLQQ 255
Cdd:PLN03130 775 VGR-QVFDkcIKDELRGKTRVLVTNQlHFLSQV----DRIILVHEGMIKEEGTYEELSNNGPLFQKLMENAGkmEEYVEE 849
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
32-225 |
2.10e-07 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 51.93 E-value: 2.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGDRS----VRQRIGYLPE------------- 94
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSpqdgLANGIVYISEdrkrdglvlgmsv 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 95 --NAYyydyLTGWEFLQLIGGifQILSSVQKKRIPELLDLVGLdrKT-AQKKQLRQYSKGMMQRIGIAQALINDPELVFF 171
Cdd:PRK10762 348 keNMS----LTALRYFSRAGG--SLKHADEQQAVSDFIRLFNI--KTpSMEQAIGLLSGGNQQKVAIARGLMTRPKVLIL 419
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 738450152 172 DEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK10762 420 DEPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGRI 473
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
32-205 |
2.12e-07 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 49.84 E-value: 2.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLG--------IVRPTSGRALILGQ----PIGdrSVRQRIGYlPenayyy 99
Cdd:cd03223 17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGlwpwgsgrIGMPEGEDLLFLPQrpylPLG--TLREQLIY-P------ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 100 dyltgWEflqliggifQILSSvqkkripelldlvgldrktaqkkqlrqyskGMMQRIGIAQALINDPELVFFDEPMSGLD 179
Cdd:cd03223 88 -----WD---------DVLSG------------------------------GEQQRLAFARLLLHKPKFVFLDEATSALD 123
|
170 180
....*....|....*....|....*..
gi 738450152 180 PigryQV-REIIQSLKQQGKTIFFNSH 205
Cdd:cd03223 124 E----ESeDRLYQLLKELGITVISVGH 146
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
28-223 |
2.67e-07 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 52.16 E-value: 2.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 28 KIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGivRPT----SGRALILGQPIGDRSVRQRIGYLPENAYYYDYLT 103
Cdd:PLN03140 892 RLQLLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAG--RKTggyiEGDIRISGFPKKQETFARISGYCEQNDIHSPQVT 969
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 104 GWEFLqLIGGIFQILSSVQKKR----IPELLDLVGLDR--------------KTAQKKqlrqyskgmmqRIGIAQALIND 165
Cdd:PLN03140 970 VRESL-IYSAFLRLPKEVSKEEkmmfVDEVMELVELDNlkdaivglpgvtglSTEQRK-----------RLTIAVELVAN 1037
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 166 PELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSHILS-DVEQICDRIALLARG 223
Cdd:PLN03140 1038 PSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSiDIFEAFDELLLMKRG 1096
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
42-219 |
4.30e-07 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 48.52 E-value: 4.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 42 GETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGqpigdrsvrqrigylPENAYYYDYLTGWEFLQLIGGifqilssv 121
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYID---------------GEDILEEVLDQLLLIIVGGKK-------- 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 122 qkkripelldlvgldrktaqkkqlRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREII------QSLKQ 195
Cdd:smart00382 59 ------------------------ASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEelrlllLLKSE 114
|
170 180
....*....|....*....|....
gi 738450152 196 QGKTIFFNSHILSDVEQICDRIAL 219
Cdd:smart00382 115 KNLTVILTTNDEKDLGPALLRRRF 138
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
10-71 |
5.96e-07 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 50.66 E-value: 5.96e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 738450152 10 LETLNLQKTYRTGfwlnkkiESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSG 71
Cdd:PRK15064 320 LEVENLTKGFDNG-------PLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSG 374
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
32-72 |
8.27e-07 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 50.33 E-value: 8.27e-07
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGR 72
Cdd:PRK11147 335 VKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGR 375
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
17-210 |
2.28e-06 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 49.26 E-value: 2.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 17 KTYRTGFWLNKKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILG----QPIGDRSVRQRIGYL 92
Cdd:PTZ00265 386 KNVRFHYDTRKDVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDshnlKDINLKWWRSKIGVV 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 93 PE-----------NAYYYDY-LTGWEFLQ----------------------LIGGIFQILSS-------VQKKRIPELL- 130
Cdd:PTZ00265 466 SQdpllfsnsiknNIKYSLYsLKDLEALSnyynedgndsqenknkrnscraKCAGDLNDMSNttdsnelIEMRKNYQTIk 545
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 131 --DLVGLDRK---------------TAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSL 193
Cdd:PTZ00265 546 dsEVVDVSKKvlihdfvsalpdkyeTLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNL 625
|
250
....*....|....*...
gi 738450152 194 K-QQGKTIFFNSHILSDV 210
Cdd:PTZ00265 626 KgNENRITIIIAHRLSTI 643
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
26-94 |
3.56e-06 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 48.39 E-value: 3.56e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 26 NKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALIlgQPigdrsvRQRIGYLPE 94
Cdd:TIGR03719 17 KKEI--LKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARP--QP------GIKVGYLPQ 75
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
26-93 |
8.60e-06 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 47.04 E-value: 8.60e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 26 NKKIesLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALIlgQPiGdrsvrQRIGYLP 93
Cdd:PRK11819 19 KKQI--LKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARP--AP-G-----IKVGYLP 76
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
42-179 |
1.11e-05 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 46.78 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 42 GETFGLLGPNGAGKTTLLKTLL-----GIvrPTSGRALILGQPI--GDRSVRQ--------RIGYLPENAYYYD------ 100
Cdd:PLN03073 203 GRHYGLVGRNGTGKTTFLRYMAmhaidGI--PKNCQILHVEQEVvgDDTTALQcvlntdieRTQLLEEEAQLVAqqrele 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 101 --YLTGWEFLQLIGGIFQILSSVQKKRIPELLDLVGLDRKTA---------------QKKQLRQYSKGMMQRIGIAQALI 163
Cdd:PLN03073 281 feTETGKGKGANKDGVDKDAVSQRLEEIYKRLELIDAYTAEAraasilaglsftpemQVKATKTFSGGWRMRIALARALF 360
|
170
....*....|....*.
gi 738450152 164 NDPELVFFDEPMSGLD 179
Cdd:PLN03073 361 IEPDLLLLDEPTNHLD 376
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
9-179 |
1.24e-05 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 46.47 E-value: 1.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 9 VLETLNLQKTYrtgfwlNKKIeSLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGrALILGQPIGDRSVRQ- 87
Cdd:TIGR03719 322 VIEAENLTKAF------GDKL-LIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSG-TIEIGETVKLAYVDQs 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 88 RIGYLPENayyydylTGWEflQLIGGIFQILssVQKKRIPELLDLVGLDRK-TAQKKQLRQYSKGMMQRIGIAQALINDP 166
Cdd:TIGR03719 394 RDALDPNK-------TVWE--EISGGLDIIK--LGKREIPSRAYVGRFNFKgSDQQKKVGQLSGGERNRVHLAKTLKSGG 462
|
170
....*....|...
gi 738450152 167 ELVFFDEPMSGLD 179
Cdd:TIGR03719 463 NVLLLDEPTNDLD 475
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
32-235 |
1.34e-05 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 45.97 E-value: 1.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLG----IVRP----TSGRALILGQPI----GDRSVRQRiGYLPENAYYY 99
Cdd:PRK13547 17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGdltgGGAPrgarVTGDVTLNGEPLaaidAPRLARLR-AVLPQAAQPA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 100 DYLTGWEFLQL-------IGGIFQILSSVQKKRIPELLDLVGLDRktaqkKQLRQYSKGMMQRIGIAQAL---------I 163
Cdd:PRK13547 96 FAFSAREIVLLgrypharRAGALTHRDGEIAWQALALAGATALVG-----RDVTTLSGGELARVQFARVLaqlwpphdaA 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738450152 164 NDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQgktifFNSHILSDVEQI------CDRIALLARGELLCVGSLDQIL 235
Cdd:PRK13547 171 QPPRYLLLDEPTAALDLAHQHRLLDTVRRLARD-----WNLGVLAIVHDPnlaarhADRIAMLADGAIVAHGAPADVL 243
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
27-241 |
1.50e-05 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 46.55 E-value: 1.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 27 KKIESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGYLPENAYYYDYLT 103
Cdd:PRK11176 354 KEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDytlASLRNQVALVSQNVHLFNDTI 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 104 GWEFLQLIGGIFQILSSVQKKRIPELLDLV-----GLDRKTAQKKQLrqYSKGMMQRIGIAQALINDPELVFFDEPMSGL 178
Cdd:PRK11176 434 ANNIAYARTEQYSREQIEEAARMAYAMDFInkmdnGLDTVIGENGVL--LSGGQRQRIAIARALLRDSPILILDEATSAL 511
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 738450152 179 DPIGRYQVREIIQSLkQQGKTIFFNSHILSDVEQiCDRIALLARGELLCVGSLDQILGRADVY 241
Cdd:PRK11176 512 DTESERAIQAALDEL-QKNRTSLVIAHRLSTIEK-ADEILVVEDGEIVERGTHAELLAQNGVY 572
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
15-249 |
3.74e-05 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 45.54 E-value: 3.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 15 LQKTYRTGFWLnkkieSLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPIGD---RSVRQRIGY 91
Cdd:PTZ00243 1314 VQMRYREGLPL-----VLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAyglRELRRQFSM 1388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 92 LPENAYYYDyltgweflqliGGIFQILSSVQKKRIPEL---LDLVGLDRKTAQKKQ---------LRQYSKGMMQRIGIA 159
Cdd:PTZ00243 1389 IPQDPVLFD-----------GTVRQNVDPFLEASSAEVwaaLELVGLRERVASESEgidsrvlegGSNYSVGQRQLMCMA 1457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 160 QALIN-DPELVFFDEPMSGLDPIGRYQVREIIQSlKQQGKTIFFNSHILSDVEQiCDRIALLARGELLCVGS-LDQILGR 237
Cdd:PTZ00243 1458 RALLKkGSGFILMDEATANIDPALDRQIQATVMS-AFSAYTVITIAHRLHTVAQ-YDKIIVMDHGAVAEMGSpRELVMNR 1535
|
250
....*....|..
gi 738450152 238 ADVYQVIVQGGG 249
Cdd:PTZ00243 1536 QSIFHSMVEALG 1547
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
30-217 |
4.18e-05 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 44.01 E-value: 4.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 30 ESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGI--VRPTSGRALILGQPIGDRSVRQRIGYLPENAYYYDY----LT 103
Cdd:PRK09580 15 AILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGRedYEVTGGTVEFKGKDLLELSPEDRAGEGIFMAFQYPVeipgVS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 104 GWEFLQliggifQILSSVQKKRIPELLDLVGLDRKTAQKKQLRQ-------------YSKGMMQRIGIAQALINDPELVF 170
Cdd:PRK09580 95 NQFFLQ------TALNAVRSYRGQEPLDRFDFQDLMEEKIALLKmpedlltrsvnvgFSGGEKKRNDILQMAVLEPELCI 168
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 738450152 171 FDEPMSGLDPIGRYQVREIIQSLkQQGKTIFFnshILSDVEQICDRI 217
Cdd:PRK09580 169 LDESDSGLDIDALKIVADGVNSL-RDGKRSFI---IVTHYQRILDYI 211
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
32-234 |
4.31e-05 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 44.46 E-value: 4.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGqpigdrsvrqRIGYLPENAYyydYLTGWEFLQLI 111
Cdd:cd03291 53 LKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSG----------RISFSSQFSW---IMPGTIKENII 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 112 GGI----FQILSSVQKKRIPELLDLVGLDRKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVR 187
Cdd:cd03291 120 FGVsydeYRYKSVVKACQLEEDITKFPEKDNTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTEKEIF 199
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 738450152 188 EIIQSLKQQGKTIFFnshILSDVEQI--CDRIALLARGELLCVGSLDQI 234
Cdd:cd03291 200 ESCVCKLMANKTRIL---VTSKMEHLkkADKILILHEGSSYFYGTFSEL 245
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
46-71 |
2.32e-04 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 42.80 E-value: 2.32e-04
10 20
....*....|....*....|....*.
gi 738450152 46 GLLGPNGAGKTTLLKTLLGIVRPTSG 71
Cdd:PRK11819 354 GIIGPNGAGKSTLFKMITGQEQPDSG 379
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
41-225 |
2.49e-04 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 42.57 E-value: 2.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 41 EGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALIlgqpigdrSVRQRIGYLPENAYYY-DY------LTG----WEFLQ 109
Cdd:PRK15064 26 GGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSL--------DPNERLGKLRQDQFAFeEFtvldtvIMGhtelWEVKQ 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 110 liggifqilssvQKKRI---PELLDLVG------------LDRKTAQKK----------QLRQYSkGMMQ--------RI 156
Cdd:PRK15064 98 ------------ERDRIyalPEMSEEDGmkvadlevkfaeMDGYTAEARagelllgvgiPEEQHY-GLMSevapgwklRV 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 157 GIAQALINDPELVFFDEPMSGLDpIgrYQVREIIQSLKQQGKTIFFNSHILSDVEQICDRIALLARGEL 225
Cdd:PRK15064 165 LLAQALFSNPDILLLDEPTNNLD-I--NTIRWLEDVLNERNSTMIIISHDRHFLNSVCTHMADLDYGEL 230
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
29-207 |
3.65e-04 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 41.16 E-value: 3.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 29 IESLKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRAL---ILGQPIGDRSVRQRigylpeNAYYYDYLT-- 103
Cdd:cd03290 14 LATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHwsnKNESEPSFEATRSR------NRYSVAYAAqk 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 104 GWEFLQLIGGIFQILSSVQKKRIPEL---------LDLVGLDRKTAQKKQLRQYSKGMMQRIGIAQALINDPELVFFDEP 174
Cdd:cd03290 88 PWLLNATVEENITFGSPFNKQRYKAVtdacslqpdIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDP 167
|
170 180 190
....*....|....*....|....*....|....*
gi 738450152 175 MSGLD-PIGRYQVRE-IIQSLKQQGKTIFFNSHIL 207
Cdd:cd03290 168 FSALDiHLSDHLMQEgILKFLQDDKRTLVLVTHKL 202
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
146-220 |
5.55e-04 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 41.55 E-value: 5.55e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 146 RQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQG-KTIFFNSHILSDVEQiCDRIALL 220
Cdd:PTZ00265 1357 KSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKAdKTIITIAHRIASIKR-SDKIVVF 1431
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
32-94 |
7.17e-04 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 41.26 E-value: 7.17e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALILGQPI---GDRSVRQRIGYLPE 94
Cdd:PLN03130 1255 LHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDIskfGLMDLRKVLGIIPQ 1320
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
32-230 |
1.02e-03 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 40.92 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 32 LKNCTLIVHEGETFGLLGPNGAGKTTLLKTLLGIVRPTSGRALilgqpiGDRSvrqrIGYLPENAyyydyltgWEFLQLI 111
Cdd:PTZ00243 676 LRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVW------AERS----IAYVPQQA--------WIMNATV 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 112 GGifQILsSVQKKRIPELLDLVGLDRKTAQKKQLR------------QYSKGMMQRIGIAQALINDPELVFFDEPMSGLD 179
Cdd:PTZ00243 738 RG--NIL-FFDEEDAARLADAVRVSQLEADLAQLGggleteigekgvNLSGGQKARVSLARAVYANRDVYLLDDPLSALD 814
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 738450152 180 P-IGRYQVREIIQSlKQQGKTIFFNSHILSDVEQiCDRIALLARGELLCVGS 230
Cdd:PTZ00243 815 AhVGERVVEECFLG-ALAGKTRVLATHQVHVVPR-ADYVVALGDGRVEFSGS 864
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
42-179 |
2.02e-03 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 39.77 E-value: 2.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 42 GETFGLLGPNGAGKTTLLKTLLGIVRPTSGRaLILGQPIgdrsvrqRIGYLPENAYyydyltgwEFLQLIGGIFQILSSV 121
Cdd:PRK10636 338 GSRIGLLGRNGAGKSTLIKLLAGELAPVSGE-IGLAKGI-------KLGYFAQHQL--------EFLRADESPLQHLARL 401
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 738450152 122 QKKRIPE-LLDLVGL-----DRKTaqkKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLD 179
Cdd:PRK10636 402 APQELEQkLRDYLGGfgfqgDKVT---EETRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLD 462
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
123-239 |
2.17e-03 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 39.81 E-value: 2.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 123 KKRIPELLDLvGLDRKTAQKKqLRQYSKGMMQRIGIAQALinDPELV----FFDEPMSGLDPIGRYQVREIIQSLKQQGK 198
Cdd:PRK00635 454 KSRLSILIDL-GLPYLTPERA-LATLSGGEQERTALAKHL--GAELIgityILDEPSIGLHPQDTHKLINVIKKLRDQGN 529
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 738450152 199 TIFFNSHilsDVEQI--CDRI------ALLARGELLCVGSLDQILGRAD 239
Cdd:PRK00635 530 TVLLVEH---DEQMIslADRIidigpgAGIFGGEVLFNGSPREFLAKSD 575
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
49-208 |
3.18e-03 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 37.93 E-value: 3.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 49 GPNGAGKTTLLKTLLGIVRPTSGRALILGQPIgDRSVRQRIGYLPENAYYYDYLTGWEFLQLIGGIFQ----ILSSVQKK 124
Cdd:PRK13541 33 GANGCGKSSLLRMIAGIMQPSSGNIYYKNCNI-NNIAKPYCTYIGHNLGLKLEMTVFENLKFWSEIYNsaetLYAAIHYF 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738450152 125 RIPELLDlvgldrktaqkKQLRQYSKGMMQRIGIAQALINDPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNS 204
Cdd:PRK13541 112 KLHDLLD-----------EKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDLLNNLIVMKANSGGIVLLSS 180
|
....
gi 738450152 205 HILS 208
Cdd:PRK13541 181 HLES 184
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
149-205 |
3.39e-03 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 37.69 E-value: 3.39e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 149 SKGMMQRIGIAQALINDPE--LVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSH 205
Cdd:cd03238 89 SGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQDINQLLEVIKGLIDLGNTVILIEH 147
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
145-217 |
4.60e-03 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 38.66 E-value: 4.60e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 738450152 145 LRQYSKGMMQRIGIAQALIN---DPELVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFF---NSHILsdveQICDRI 217
Cdd:PRK00635 807 LSSLSGGEIQRLKLAYELLApskKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQGHTVVIiehNMHVV----KVADYV 881
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
132-205 |
4.66e-03 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 38.14 E-value: 4.66e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 738450152 132 LVGLDRKTAQKKQLRQYSKGMMQRIGIAQALINDPE---LVFFDEPMSGLDPIGRYQVREIIQSLKQQGKTIFFNSH 205
Cdd:pfam13304 221 LILLENGGGGELPAFELSDGTKRLLALLAALLSALPkggLLLIDEPESGLHPKLLRRLLELLKELSRNGAQLILTTH 297
|
|
| |
