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Conserved domains on  [gi|740727156|ref|WP_038512442|]
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methyl-accepting chemotaxis protein [Vibrio coralliilyticus]

Protein Classification

methyl-accepting chemotaxis protein( domain architecture ID 11435591)

methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior

CATH:  1.10.287.950
Gene Ontology:  GO:0006935
PubMed:  18165013|20738376
SCOP:  4003862

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
172-670 5.82e-97

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


:

Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 308.49  E-value: 5.82e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 172 TALDRTLNQDLPSIRYYLELVDEAGDMIATLNAYIMGDPAARDTFNNDAGAFAGYLDKLRPLEPDPQASSQIDEVEQYYY 251
Cdd:COG0840   36 LLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLAALAALLAL 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 252 DIIRIAQEVFEGYDPSGKRSANMLVGELKQSIILPLEEILNNSATEETNDSIQALAELNNNMSTIIFWLTINVIVVLVVG 331
Cdd:COG0840  116 LELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALA 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 332 IAVAWGLLNIIRQRLDVIAAKAKSIADGDLSEPpINETNKDELGELARAIDAMQQSLRSVLSNITSVASEVASNTQMVED 411
Cdd:COG0840  196 IILALLLSRSITRPLRELLEVLERIAEGDLTVR-IDVDSKDEIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAA 274

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 412 TTKLVASGIEEQADKATLIASAVEEMTVTVNQVADQSTDAAASSRQAGEEATNGGKLMQETVNGMNRISEVVNETAETVD 491
Cdd:COG0840  275 SAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIE 354

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 492 SLGKRGEEIGNVIKVINDIAEQTNLLALNAAIEAARAGELGRGFAVVADEVRSLAERTSKATEEVGGLISSIQNETRQAV 571
Cdd:COG0840  355 ELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAV 434

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 572 ERMSEGTHLVAEGVTLSNSAGDALTQIVSRAQDVNQMIDMIATAGNEQATAAQEMSRDINTISQIADNSVRTTQDGAQAV 651
Cdd:COG0840  435 EAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAA 514

                        490
                 ....*....|....*....
gi 740727156 652 SQLYRKVEELEQVVARFKL 670
Cdd:COG0840  515 EELAELAEELQELVSRFKL 533
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
172-670 5.82e-97

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 308.49  E-value: 5.82e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 172 TALDRTLNQDLPSIRYYLELVDEAGDMIATLNAYIMGDPAARDTFNNDAGAFAGYLDKLRPLEPDPQASSQIDEVEQYYY 251
Cdd:COG0840   36 LLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLAALAALLAL 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 252 DIIRIAQEVFEGYDPSGKRSANMLVGELKQSIILPLEEILNNSATEETNDSIQALAELNNNMSTIIFWLTINVIVVLVVG 331
Cdd:COG0840  116 LELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALA 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 332 IAVAWGLLNIIRQRLDVIAAKAKSIADGDLSEPpINETNKDELGELARAIDAMQQSLRSVLSNITSVASEVASNTQMVED 411
Cdd:COG0840  196 IILALLLSRSITRPLRELLEVLERIAEGDLTVR-IDVDSKDEIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAA 274

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 412 TTKLVASGIEEQADKATLIASAVEEMTVTVNQVADQSTDAAASSRQAGEEATNGGKLMQETVNGMNRISEVVNETAETVD 491
Cdd:COG0840  275 SAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIE 354

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 492 SLGKRGEEIGNVIKVINDIAEQTNLLALNAAIEAARAGELGRGFAVVADEVRSLAERTSKATEEVGGLISSIQNETRQAV 571
Cdd:COG0840  355 ELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAV 434

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 572 ERMSEGTHLVAEGVTLSNSAGDALTQIVSRAQDVNQMIDMIATAGNEQATAAQEMSRDINTISQIADNSVRTTQDGAQAV 651
Cdd:COG0840  435 EAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAA 514

                        490
                 ....*....|....*....
gi 740727156 652 SQLYRKVEELEQVVARFKL 670
Cdd:COG0840  515 EELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 416-669 1.83e-68

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 224.47  E-value: 1.83e-68
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156   416 VASGIEEQADKATLIASAVEEMTVTVNQVADQSTDAAASSRQAGEEATNGGKLMQETVNGMNRISEVVNETAETVDSLGK 495
Cdd:smart00283   9 IAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAVSAVEELEE 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156   496 RGEEIGNVIKVINDIAEQTNLLALNAAIEAARAGELGRGFAVVADEVRSLAERTSKATEEVGGLISSIQNETRQAVERMS 575
Cdd:smart00283  89 SSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEETNEAVAAME 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156   576 EGTHLVAEGVTLSNSAGDALTQIVSRAQDVNQMIDMIATAGNEQATAAQEMSRDINTISQIADNSVRTTQDGAQAVSQLY 655
Cdd:smart00283 169 ESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEISAAAEELS 248

                          250
                   ....*....|....
gi 740727156   656 RKVEELEQVVARFK 669
Cdd:smart00283 249 GLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 435-634 5.11e-60

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 199.77  E-value: 5.11e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 435 EEMTVTVNQVADQSTDAAASSRQAGEEATNGGKLMQETVNGMNRISEVVNETAETVDSLGKRGEEIGNVIKVINDIAEQT 514
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 515 NLLALNAAIEAARAGELGRGFAVVADEVRSLAERTSKATEEVGGLISSIQNETRQAVERMSEGTHLVAEGVTLSNSAGDA 594
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 740727156 595 LTQIVSRAQDVNQMIDMIATAGNEQATAAQEMSRDINTIS 634
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
293-670 1.06e-49

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 181.81  E-value: 1.06e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 293 NSATEETNDSIQALAE---LNNNMSTIIFwLTINVIVVLVVGIAVAWGLlNIIRQRLDVIAAKAKSIADGDLSEPpINET 369
Cdd:PRK09793 164 EAWQLEINHVLEAASAqsqRNYQISALVF-ISMIIVAAIYISSALWWTR-KMIVQPLAIIGSHFDSIAAGNLARP-IAVY 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 370 NKDELGELARAIDAMQQSLRSVLSNITSVASEVASNTQMVEDTTKLVASGIEEQADKATLIASAVEEMTVTVNQVADQST 449
Cdd:PRK09793 241 GRNEITAIFASLKTMQQALRGTVSDVRKGSQEMHIGIAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNAR 320

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 450 DAAASSRQAGEEATNGGklmqetvngmnrisEVVNETAETVDSLGKRGEEIGNVIKVINDIAEQTNLLALNAAIEAARAG 529
Cdd:PRK09793 321 QASELAKNAATTAQAGG--------------VQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAG 386

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 530 ELGRGFAVVADEVRSLAERTSKATEEVGGLIssiqnetRQAVERMSEGTHLVaegvtlsNSAGDALTQIVSRAQDVNQMI 609
Cdd:PRK09793 387 EQGRGFAVVAGEVRNLASRSAQAAKEIKGLI-------EESVNRVQQGSKLV-------NNAAATMTDIVSSVTRVNDIM 452

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 740727156 610 DMIATAGNEQATAAQEMSRDINTISQIADNSVRTTQDGAQAVSQLYRKVEELEQVVARFKL 670
Cdd:PRK09793 453 GEIASASEEQRRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRVAVFTL 513
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 452-636 8.34e-43

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 152.20  E-value: 8.34e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156  452 AASSRQAGEEATNGGKLMQETVNGMNRISevvnetaetvdslgKRGEEIGNVIKVINDIAEQTNLLALNAAIEAARAGEL 531
Cdd:pfam00015   1 SDLAQLASEEAQDGGKEVANVVGQMEQIA--------------QSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQ 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156  532 GRGFAVVADEVRSLAERTSKATEEVGGLISSIQNETRQAVERMSEGTHLVAEGVTLSNSAGDALTQIVSRAQDVNQMIDM 611
Cdd:pfam00015  67 GRGFAVVADEVRKLAERSAQAAKEIEALIIEIQKQTNDSTASIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQE 146

                         170       180
                  ....*....|....*....|....*
gi 740727156  612 IATAGNEQATAAQEMSRDINTISQI 636
Cdd:pfam00015 147 IAAASDEQSAGIDQVNQAVARMDQV 171
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
172-670 5.82e-97

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 308.49  E-value: 5.82e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 172 TALDRTLNQDLPSIRYYLELVDEAGDMIATLNAYIMGDPAARDTFNNDAGAFAGYLDKLRPLEPDPQASSQIDEVEQYYY 251
Cdd:COG0840   36 LLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLAALAALLAL 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 252 DIIRIAQEVFEGYDPSGKRSANMLVGELKQSIILPLEEILNNSATEETNDSIQALAELNNNMSTIIFWLTINVIVVLVVG 331
Cdd:COG0840  116 LELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALA 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 332 IAVAWGLLNIIRQRLDVIAAKAKSIADGDLSEPpINETNKDELGELARAIDAMQQSLRSVLSNITSVASEVASNTQMVED 411
Cdd:COG0840  196 IILALLLSRSITRPLRELLEVLERIAEGDLTVR-IDVDSKDEIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAA 274

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 412 TTKLVASGIEEQADKATLIASAVEEMTVTVNQVADQSTDAAASSRQAGEEATNGGKLMQETVNGMNRISEVVNETAETVD 491
Cdd:COG0840  275 SAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIE 354

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 492 SLGKRGEEIGNVIKVINDIAEQTNLLALNAAIEAARAGELGRGFAVVADEVRSLAERTSKATEEVGGLISSIQNETRQAV 571
Cdd:COG0840  355 ELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAV 434

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 572 ERMSEGTHLVAEGVTLSNSAGDALTQIVSRAQDVNQMIDMIATAGNEQATAAQEMSRDINTISQIADNSVRTTQDGAQAV 651
Cdd:COG0840  435 EAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAA 514

                        490
                 ....*....|....*....
gi 740727156 652 SQLYRKVEELEQVVARFKL 670
Cdd:COG0840  515 EELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 416-669 1.83e-68

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 224.47  E-value: 1.83e-68
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156   416 VASGIEEQADKATLIASAVEEMTVTVNQVADQSTDAAASSRQAGEEATNGGKLMQETVNGMNRISEVVNETAETVDSLGK 495
Cdd:smart00283   9 IAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAVSAVEELEE 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156   496 RGEEIGNVIKVINDIAEQTNLLALNAAIEAARAGELGRGFAVVADEVRSLAERTSKATEEVGGLISSIQNETRQAVERMS 575
Cdd:smart00283  89 SSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEETNEAVAAME 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156   576 EGTHLVAEGVTLSNSAGDALTQIVSRAQDVNQMIDMIATAGNEQATAAQEMSRDINTISQIADNSVRTTQDGAQAVSQLY 655
Cdd:smart00283 169 ESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEISAAAEELS 248

                          250
                   ....*....|....
gi 740727156   656 RKVEELEQVVARFK 669
Cdd:smart00283 249 GLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 435-634 5.11e-60

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 199.77  E-value: 5.11e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 435 EEMTVTVNQVADQSTDAAASSRQAGEEATNGGKLMQETVNGMNRISEVVNETAETVDSLGKRGEEIGNVIKVINDIAEQT 514
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 515 NLLALNAAIEAARAGELGRGFAVVADEVRSLAERTSKATEEVGGLISSIQNETRQAVERMSEGTHLVAEGVTLSNSAGDA 594
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 740727156 595 LTQIVSRAQDVNQMIDMIATAGNEQATAAQEMSRDINTIS 634
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
293-670 1.06e-49

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 181.81  E-value: 1.06e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 293 NSATEETNDSIQALAE---LNNNMSTIIFwLTINVIVVLVVGIAVAWGLlNIIRQRLDVIAAKAKSIADGDLSEPpINET 369
Cdd:PRK09793 164 EAWQLEINHVLEAASAqsqRNYQISALVF-ISMIIVAAIYISSALWWTR-KMIVQPLAIIGSHFDSIAAGNLARP-IAVY 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 370 NKDELGELARAIDAMQQSLRSVLSNITSVASEVASNTQMVEDTTKLVASGIEEQADKATLIASAVEEMTVTVNQVADQST 449
Cdd:PRK09793 241 GRNEITAIFASLKTMQQALRGTVSDVRKGSQEMHIGIAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNAR 320

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 450 DAAASSRQAGEEATNGGklmqetvngmnrisEVVNETAETVDSLGKRGEEIGNVIKVINDIAEQTNLLALNAAIEAARAG 529
Cdd:PRK09793 321 QASELAKNAATTAQAGG--------------VQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAG 386

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 530 ELGRGFAVVADEVRSLAERTSKATEEVGGLIssiqnetRQAVERMSEGTHLVaegvtlsNSAGDALTQIVSRAQDVNQMI 609
Cdd:PRK09793 387 EQGRGFAVVAGEVRNLASRSAQAAKEIKGLI-------EESVNRVQQGSKLV-------NNAAATMTDIVSSVTRVNDIM 452

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 740727156 610 DMIATAGNEQATAAQEMSRDINTISQIADNSVRTTQDGAQAVSQLYRKVEELEQVVARFKL 670
Cdd:PRK09793 453 GEIASASEEQRRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRVAVFTL 513
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 212-670 2.24e-47

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 175.58  E-value: 2.24e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 212 ARDTFNNDAGAFAGYlDKLRPLEPDPQASSQIDEVEQYYYDIIRIAQEVFEgydpSGKRSAnmLVGELKQSIILPLEEIL 291
Cdd:PRK15048  93 ARKTLAQAATHYKKF-KSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLD----YGNTGA--YFAQPTQGMQNAMGEAF 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 292 NNSATEETNDSIQALAELNNNMSTIIFWLTINVIVVLVVGIAVAWGLLNIIRQRLDVIAAKAKSIADGDLSEPpINETNK 371
Cdd:PRK15048 166 AQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLTPLAKIIAHIREIAGGNLANT-LTIDGR 244

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 372 DELGELARAIDAMQQSLRSVLSNITSVASEVASNTQMVEDTTKLVASGIEEQADKATLIASAVEEMTVTVNQVADQSTDA 451
Cdd:PRK15048 245 SEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQA 324

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 452 AASSRQAGEEATNGGKLMQETVNGMNRISevvnetaetvDSLGKrgeeIGNVIKVINDIAEQTNLLALNAAIEAARAGEL 531
Cdd:PRK15048 325 SQLAQSASDTAQHGGKVVDGVVKTMHEIA----------DSSKK----IADIISVIDGIAFQTNILALNAAVEAARAGEQ 390

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 532 GRGFAVVADEVRSLAERTSKATEEVGGLISSiqnetrqAVERMSEGTHLVaegvtlsNSAGDALTQIVSRAQDVNQMIDM 611
Cdd:PRK15048 391 GRGFAVVAGEVRNLASRSAQAAKEIKALIED-------SVSRVDTGSVLV-------ESAGETMNNIVNAVTRVTDIMGE 456

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 740727156 612 IATAGNEQATAAQEMSRDINTISQIADNSVRTTQDGAQAVSQLYRKVEELEQVVARFKL 670
Cdd:PRK15048 457 IASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQAVSAFRL 515
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
298-670 4.31e-43

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 163.59  E-value: 4.31e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 298 ETNDSIQALAELNNNMS-TIIFWLTINV-IVVLVVGIAVAWGLLNIIRQRLDVIAAKAKSIADGDLSEPpINETNKDELG 375
Cdd:PRK15041 172 EQNDRLYDIAVSDNNASySQAMWILVGVmIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKP-IEVDGSNEMG 250

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 376 ELARAIDAMQQSLRSVLSNITSVASEVASNTQMVEDTTKLVASGIEEQADKATLIASAVEEMTVTVNQVADQSTDAAASS 455
Cdd:PRK15041 251 QLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLA 330

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 456 RQAGEEATNGGKlmqetvngmnriseVVNETAETVDSLGKRGEEIGNVIKVINDIAEQTNLLALNAAIEAARAGELGRGF 535
Cdd:PRK15041 331 LSASETAQRGGK--------------VVDNVVQTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGF 396

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 536 AVVADEVRSLAERTSKATEEVGGLISSiqnetrqAVERMSEGThlvaegvTLSNSAGDALTQIVSRAQDVNQMIDMIATA 615
Cdd:PRK15041 397 AVVAGEVRNLAQRSAQAAREIKSLIED-------SVGKVDVGS-------TLVESAGETMAEIVSAVTRVTDIMGEIASA 462

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 740727156 616 GNEQATAAQEMSRDINTISQIADNSVRTTQDGAQAVSQLYRKVEELEQVVARFKL 670
Cdd:PRK15041 463 SDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRLTEAVAVFRI 517
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 452-636 8.34e-43

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 152.20  E-value: 8.34e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156  452 AASSRQAGEEATNGGKLMQETVNGMNRISevvnetaetvdslgKRGEEIGNVIKVINDIAEQTNLLALNAAIEAARAGEL 531
Cdd:pfam00015   1 SDLAQLASEEAQDGGKEVANVVGQMEQIA--------------QSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQ 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156  532 GRGFAVVADEVRSLAERTSKATEEVGGLISSIQNETRQAVERMSEGTHLVAEGVTLSNSAGDALTQIVSRAQDVNQMIDM 611
Cdd:pfam00015  67 GRGFAVVADEVRKLAERSAQAAKEIEALIIEIQKQTNDSTASIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQE 146

                         170       180
                  ....*....|....*....|....*
gi 740727156  612 IATAGNEQATAAQEMSRDINTISQI 636
Cdd:pfam00015 147 IAAASDEQSAGIDQVNQAVARMDQV 171
NtrY COG5000
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ...
 315-397 2.76e-07

Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];


Pssm-ID: 444024 [Multi-domain]  Cd Length: 422  Bit Score: 53.43  E-value: 2.76e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 315 TIIFWLTINVIVVLVVGIAVAWGLLNIIRQRLDVIAAKAKSIADGDLSePPINETNKDELGELARAIDAMQQSLR----- 389
Cdd:COG5000    6 LFLLLLLLIALLLLLLALWLALLLARRLTRPLRRLAEATRAVAAGDLS-VRLPVTGDDEIGELARAFNRMTDQLKeqree 84

                         90
                 ....*....|....*..
gi 740727156 390 ---------SVLSNITS 397
Cdd:COG5000   85 leerrryleTILENLPA 101
HAMP pfam00672
HAMP domain;
338-389 3.02e-07

HAMP domain;


Pssm-ID: 459898 [Multi-domain]  Cd Length: 53  Bit Score: 47.62  E-value: 3.02e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 740727156  338 LLNIIRQRLDVIAAKAKSIADGDLSEPpINETNKDELGELARAIDAMQQSLR 389
Cdd:pfam00672   2 LARRILRPLRRLAEAARRIASGDLDVR-LPVSGRDEIGELARAFNQMAERLR 52
HAMP cd06225
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ...
 344-388 6.89e-07

Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.


Pssm-ID: 381743 [Multi-domain]  Cd Length: 45  Bit Score: 46.28  E-value: 6.89e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 740727156 344 QRLDVIAAKAKSIADGDLSEPpINETNKDELGELARAIDAMQQSL 388
Cdd:cd06225    2 RPLRRLTEAARRIAEGDLDVR-VPVRSKDEIGELARAFNQMAERL 45
HAMP smart00304
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
340-389 7.69e-07

HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;


Pssm-ID: 197640 [Multi-domain]  Cd Length: 53  Bit Score: 46.47  E-value: 7.69e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 740727156   340 NIIRQRLDVIAAKAKSIADGDLSEPpINETNKDELGELARAIDAMQQSLR 389
Cdd:smart00304   1 RRLLRPLRRLAEAAQRIADGDLTVR-LPVDGRDEIGELARAFNEMADRLE 49
HAMP COG2770
HAMP domain [Signal transduction mechanisms];
110-654 3.17e-05

HAMP domain [Signal transduction mechanisms];


Pssm-ID: 442051 [Multi-domain]  Cd Length: 631  Bit Score: 47.03  E-value: 3.17e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 110 RIISLANQYIERVNQGIFTKFNPADEQQAIDKINQLTKNIGAPLEDLLDQLAEKRFTEAYKSTALDRTLNQDLPSIRYYL 189
Cdd:COG2770    4 LLLALLLLLLLLLLLLLLAGALLVLALISLRLLLALLLLLLLLLALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLLS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 190 ELVDEAGDMIATLNAYIMGDPAARDTFNNDAGAFAGYLDKLRPLEPDPQASSQIDEVEQYYYDIIRIAQEVFEGYDPSGK 269
Cdd:COG2770   84 LVALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 270 RSANMLVGELKQSIILPLEEILNNSATEETNDSIQALAELNNNMSTIIFWLTINVIVVLVVGIAVAWGLLNIIRQRLDVI 349
Cdd:COG2770  164 LALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLARRITRPLRRL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 350 AAKAKSIADGDLSEPpINETNKDELGELARAIDAMQQSLRS-----VLSNITSVASEVASNTQMVEDTTKLVASGIEEQA 424
Cdd:COG2770  244 AEAARRIAAGDLDVR-IPVSRKDEIGELARAFNRMADSLREsieeaEEEEELAEAELARLLEALLELLLALLLLLLALLL 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 425 DKATLIASAVEEMTVTVNQVADQSTDAAASSRQAGEEATNGGKLMQETVNGMNRISEVVNETAETVDSLGKRGEEIGNVI 504
Cdd:COG2770  323 LAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAAL 402

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 505 KVINDIAEQTNLLALNAAIEAARAGELGRGFAVVADEVRSLAERTSKATEEVGGLISSIQNETRQAVERMSEGTHLVAEG 584
Cdd:COG2770  403 LLLELALEELVLALLALALLALAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLA 482

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 585 VTLSNSAGDALTQIVSRAQDVNQMIDMIATAGNEQATAAQEMSRDINTISQIADNSVRTTQDGAQAVSQL 654
Cdd:COG2770  483 ALGALELLLLEEEEEAGAAAEELAEELLLLEGLLLLLLLEAEALEVAEELLELEEAALLLAAAAELAALL 552
COG4192 COG4192
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ...
 261-390 3.77e-04

Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];


Pssm-ID: 443346 [Multi-domain]  Cd Length: 640  Bit Score: 43.52  E-value: 3.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 261 FEGYDPSGKRSANMLVGELKQ------SIILPLEEILNNSATEETNDSIQALAELNNNMSTIIFWLTINVIVVLVVGIAV 334
Cdd:COG4192  263 GEGGLPSLRRDELAAQATLEAlaeennSILEQLRTQISGLVGNSREQLVALNQETAQLVQQSGILLLAIALLSLLLAVLI 342

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 740727156 335 AWGLLN--IIRqRLDVIAAKAKSIADGDLSEPpINETNKDELGELARAI----DAMQQSLRS 390
Cdd:COG4192  343 NYFYVRrrLVK-RLNALSDAMAAIAAGDLDVP-IPVDGNDEIGRIARLLrvfrDQAIEKTQE 402
NarQ COG3850
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ...
 211-626 4.72e-03

Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];


Pssm-ID: 443059 [Multi-domain]  Cd Length: 448  Bit Score: 39.87  E-value: 4.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 211 AARDTFNNDAGAFAGYLDKLRPLEPDPQASSQIDEVEQYYYDIIRIAQEVFEGYDPSGKRSANMLVGELKQSIILPLEEI 290
Cdd:COG3850   11 LLRLLLALLALLLLALLLLSLLALLLLLERTLLRLLSLLASAGLLAALLAALLLLLSLGLLALLLALLLLLLLLLLAALL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 291 LNNSATEETNDSIQALAELNNNMSTIIFWLTINVIVVLVVGIAVAWGLLNIIRQRLDVIAAKAKSIADGDLSEPpINETN 370
Cdd:COG3850   91 SLLLLLLLLLLLLLLLLLLLLAAAINRKLALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDAR-VPVSG 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 371 KDELGELARAIDAMQQSLRSVLSNITSVASEVASNTQMVEDTTKLVASGIEEQADKATLIASAVEEMTVTVNQVADQSTD 450
Cdd:COG3850  170 RDELGTLARAFNRMADELQELYAELEEEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALA 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 451 AAASSRQAGEEATNGGKLMQETVNGMNRISEVVNETAETVDSLGKRGEEIGNVIKVINDIAEQTNLLALNAAIEAARAGE 530
Cdd:COG3850  250 ESELLALNILAGLLELLLALLLLLLASALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLL 329

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740727156 531 LGRGFAVVADEVRSLAERTSKATEEVGGLISSIQNETRQAVERMSEGTHLVAEGVTLSNSAGDALTQIVSRAQDVNQMID 610
Cdd:COG3850  330 LIALASVVAALLELASILALQAALEAAAAGAALAAAAAAAGLARALAQAGADAAEALGLLAEASEGAAGQGAGLVDVEGG 409

                        410
                 ....*....|....*.
gi 740727156 611 MIATAGNEQATAAQEM 626
Cdd:COG3850  410 VAGEGGLVVLIVSIIA 425
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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