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Conserved domains on  [gi|740843297|ref|WP_038628550|]
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MULTISPECIES: PH domain-containing protein [Corynebacterium]

Protein Classification

PH domain-containing protein( domain architecture ID 10566658)

bacterial Pleckstrin homology (bPH) domain-containing protein may be involved in protein-protein interactions; similar to Mycobacterium tuberculosis low molecular weight protein antigen 6 (CFP-6)

CATH:  2.30.29.50
Gene Ontology:  GO:0005515
PubMed:  15493994|22728242|19913036|17233582
SCOP:  4002395

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
bPH_6 pfam10756
Bacterial PH domain; This domain has a bacterial type PH domain structure. This domain was ...
 58-130 1.41e-12

Bacterial PH domain; This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.


:

Pssm-ID: 431475  Cd Length: 73  Bit Score: 59.99  E-value: 1.41e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 740843297   58 RVRTTVGSRGITAVYLLSQRRsVPWSDFAGIFFNKGGR-AFAVTKSDERIALPAISFNSLPELKEATGGLIPDP 130
Cdd:pfam10756   1 RPRVRADPDGLEVRNLFGTRR-LPWEDIAGVRFPEGRRwARLDLTDGELVPLPAVQLGDLPQLAAAALRRLRDA 73
 
Name Accession Description Interval E-value
bPH_6 pfam10756
Bacterial PH domain; This domain has a bacterial type PH domain structure. This domain was ...
 58-130 1.41e-12

Bacterial PH domain; This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.


Pssm-ID: 431475  Cd Length: 73  Bit Score: 59.99  E-value: 1.41e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 740843297   58 RVRTTVGSRGITAVYLLSQRRsVPWSDFAGIFFNKGGR-AFAVTKSDERIALPAISFNSLPELKEATGGLIPDP 130
Cdd:pfam10756   1 RPRVRADPDGLEVRNLFGTRR-LPWEDIAGVRFPEGRRwARLDLTDGELVPLPAVQLGDLPQLAAAALRRLRDA 73
 
Name Accession Description Interval E-value
bPH_6 pfam10756
Bacterial PH domain; This domain has a bacterial type PH domain structure. This domain was ...
 58-130 1.41e-12

Bacterial PH domain; This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.


Pssm-ID: 431475  Cd Length: 73  Bit Score: 59.99  E-value: 1.41e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 740843297   58 RVRTTVGSRGITAVYLLSQRRsVPWSDFAGIFFNKGGR-AFAVTKSDERIALPAISFNSLPELKEATGGLIPDP 130
Cdd:pfam10756   1 RPRVRADPDGLEVRNLFGTRR-LPWEDIAGVRFPEGRRwARLDLTDGELVPLPAVQLGDLPQLAAAALRRLRDA 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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