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Conserved domains on  [gi|740843811|ref|WP_038629064|]
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MULTISPECIES: aldolase [Serratia]

Protein Classification

class II aldolase/adducin family protein( domain architecture ID 10013004)

class II aldolase/adducin family protein similar to 3-oxo-tetronate 4-phosphate decarboxylase, which catalyzes decarboxylation of 3-oxo-tetronate 4-phosphate to dihydroxyacetone phosphate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK08130 PRK08130
putative aldolase; Validated
 4-210 1.27e-140

putative aldolase; Validated


:

Pssm-ID: 181241 [Multi-domain]  Cd Length: 213  Bit Score: 391.16  E-value: 1.27e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   4 TTEQQAREEMVRLGASFFQRGYATGSAGNLSLLLPDGALLATPTGSCLGELQADRLSKVSLNGDWLSGDKPSKEISFHRA 83
Cdd:PRK08130   1 MTEQALREEIVRLGRSLFQRGYTVGSAGNISARLDDGGWLVTPTGSCLGRLDPARLSKVDADGNWLSGDKPSKEVPLHRA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  84 LYLNNPECKAVVHLHCTYLTALSCLQGLDADNAIKPFTPYVVMRVGKVPVVPYYRPGDERLAQDLARLAPTHRAFLLANH 163
Cdd:PRK08130  81 IYRNNPECGAVVHLHSTHLTALSCLGGLDPTNVLPPFTPYYVMRVGHVPLIPYYRPGDPAIAEALAGLAARYRAVLLANH 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 740843811 164 GPVVTGKDLRAAADNAEEMEDAARLIFTLGDRPIRYLTDDEIAELRS 210
Cdd:PRK08130 161 GPVVWGSSLEAAVNATEELEETAKLILLLGGRPPRYLTDEEIAELRS 207
 
Name Accession Description Interval E-value
PRK08130 PRK08130
putative aldolase; Validated
 4-210 1.27e-140

putative aldolase; Validated


Pssm-ID: 181241 [Multi-domain]  Cd Length: 213  Bit Score: 391.16  E-value: 1.27e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   4 TTEQQAREEMVRLGASFFQRGYATGSAGNLSLLLPDGALLATPTGSCLGELQADRLSKVSLNGDWLSGDKPSKEISFHRA 83
Cdd:PRK08130   1 MTEQALREEIVRLGRSLFQRGYTVGSAGNISARLDDGGWLVTPTGSCLGRLDPARLSKVDADGNWLSGDKPSKEVPLHRA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  84 LYLNNPECKAVVHLHCTYLTALSCLQGLDADNAIKPFTPYVVMRVGKVPVVPYYRPGDERLAQDLARLAPTHRAFLLANH 163
Cdd:PRK08130  81 IYRNNPECGAVVHLHSTHLTALSCLGGLDPTNVLPPFTPYYVMRVGHVPLIPYYRPGDPAIAEALAGLAARYRAVLLANH 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 740843811 164 GPVVTGKDLRAAADNAEEMEDAARLIFTLGDRPIRYLTDDEIAELRS 210
Cdd:PRK08130 161 GPVVWGSSLEAAVNATEELEETAKLILLLGGRPPRYLTDEEIAELRS 207
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 4-209 1.27e-71

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 216.23  E-value: 1.27e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   4 TTEQQAREEMVRLGASFFQRGYATGSAGNLSLLLPDGALLATPTGSCLGELQADRLSKVSLNGDWLSGD-KPSKEISFHR 82
Cdd:COG0235    1 MEEEELREELAAAGRRLARRGLVDGTAGNISVRLDDDRFLITPSGVDFGELTPEDLVVVDLDGNVVEGDlKPSSETPLHL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  83 ALYLNNPECKAVVHLHCTYLTALSCLQGldadnAIKPF-TPYVVMRVGKVPVVPYYRPGDERLAQDLARLAPTHRAFLLA 161
Cdd:COG0235   81 AIYRARPDVGAVVHTHSPYATALSALGE-----PLPPLeQTEAAAFLGDVPVVPYAGPGTEELAEAIAEALGDRPAVLLR 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 740843811 162 NHGPVVTGKDLRAAADNAEEMEDAARL-IFTLGDRPIRYLTDDEIAELR 209
Cdd:COG0235  156 NHGVVVWGKDLAEAFDRAEVLEEAARIqLLALALGGPLVLSDEEIDKLA 204
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 11-188 6.27e-60

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 185.44  E-value: 6.27e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   11 EEMVRLGASFFQRGYATGSAGNLSLLLPDGALLATPTGSCLGELQADRLSKVSLNGDWLS-GDKPSKEISFHRALYLNNP 89
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRLPGDGFLITPSGVDFGELTPEDLVVVDLDGNVVEgGLKPSSETPLHLAIYRARP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   90 ECKAVVHLHCTYLTALSCLQgldadNAIKPFTPYVVMRVGK-VPVVPYYRPGDERLAQDLAR-LAPTHRAFLLANHGPVV 167
Cdd:pfam00596  81 DAGAVVHTHSPYATALSLAK-----EGLPPITQEAADFLGGdIPIIPYYTPGTEELGERIAEaLGGDRKAVLLRNHGLLV 155

                         170       180
                  ....*....|....*....|.
gi 740843811  168 TGKDLRAAADNAEEMEDAARL 188
Cdd:pfam00596 156 WGKTLEEAFYLAEELERAAEI 176
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 13-188 7.22e-49

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 157.80  E-value: 7.22e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811    13 MVRLGASFFQRGYATGSAGNLSL-LLPDGALLATPTGSCLGELQADRLSKVSLNG---DWLSGDKPSKEISFHRALYLNN 88
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISArVGEEDLFLITPSGVDFGELTASDLVVVDLDGnvvEGGGGPKPSSETPLHLAIYRAR 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811    89 PECKAVVHLHCTYLTALSCLqgldADNAIKPFTPYVVMRVG-KVPVVPYYRPGD------ERLAQDLARLAPTHRAFLLA 161
Cdd:smart01007  81 PDVGAVVHTHSPYATALAAL----GKPLPLLPTEQAAAFLGgEIPYAPYAGPGTelaeegAELAEALAEALPDRPAVLLR 156

                          170       180
                   ....*....|....*....|....*..
gi 740843811   162 NHGPVVTGKDLRAAADNAEEMEDAARL 188
Cdd:smart01007 157 NHGLLVWGKTLEEAFDLAEELEEAAEI 183
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 20-193 3.82e-30

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 110.53  E-value: 3.82e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  20 FFQRGYATGSAGNLSLLLPD-GALLATPTGSCLGELQADRLSKVSLNGDWLSGDKPSKEISFHRALYLNNPECKAVVHLH 98
Cdd:cd00398   14 LDLYGWVTGTGGNVSARDRDrGYFLITPSGVDYEEMTASDLVVVDAQGKVVEGKKPSSETPLHLALYRARPDIGCIVHTH 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  99 CTYLTALSCLQGLDAdnaikPFTPY--VVMRVGKVPVVPYYRPGDE--RLAQDLARLAPTHRAFLLANHGPVVTGKDLRA 174
Cdd:cd00398   94 STHATAVSQLKEGLI-----PAGHTacAVYFTGDIPCTPYMTPETGedEIGTQRALGFPNSKAVLLRNHGLFAWGPTLDE 168

                        170       180
                 ....*....|....*....|
gi 740843811 175 AADNAEEMEDAARL-IFTLG 193
Cdd:cd00398  169 AFHLAVVLEVAAEIqLKALS 188
 
Name Accession Description Interval E-value
PRK08130 PRK08130
putative aldolase; Validated
 4-210 1.27e-140

putative aldolase; Validated


Pssm-ID: 181241 [Multi-domain]  Cd Length: 213  Bit Score: 391.16  E-value: 1.27e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   4 TTEQQAREEMVRLGASFFQRGYATGSAGNLSLLLPDGALLATPTGSCLGELQADRLSKVSLNGDWLSGDKPSKEISFHRA 83
Cdd:PRK08130   1 MTEQALREEIVRLGRSLFQRGYTVGSAGNISARLDDGGWLVTPTGSCLGRLDPARLSKVDADGNWLSGDKPSKEVPLHRA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  84 LYLNNPECKAVVHLHCTYLTALSCLQGLDADNAIKPFTPYVVMRVGKVPVVPYYRPGDERLAQDLARLAPTHRAFLLANH 163
Cdd:PRK08130  81 IYRNNPECGAVVHLHSTHLTALSCLGGLDPTNVLPPFTPYYVMRVGHVPLIPYYRPGDPAIAEALAGLAARYRAVLLANH 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 740843811 164 GPVVTGKDLRAAADNAEEMEDAARLIFTLGDRPIRYLTDDEIAELRS 210
Cdd:PRK08130 161 GPVVWGSSLEAAVNATEELEETAKLILLLGGRPPRYLTDEEIAELRS 207
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 4-209 1.27e-71

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 216.23  E-value: 1.27e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   4 TTEQQAREEMVRLGASFFQRGYATGSAGNLSLLLPDGALLATPTGSCLGELQADRLSKVSLNGDWLSGD-KPSKEISFHR 82
Cdd:COG0235    1 MEEEELREELAAAGRRLARRGLVDGTAGNISVRLDDDRFLITPSGVDFGELTPEDLVVVDLDGNVVEGDlKPSSETPLHL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  83 ALYLNNPECKAVVHLHCTYLTALSCLQGldadnAIKPF-TPYVVMRVGKVPVVPYYRPGDERLAQDLARLAPTHRAFLLA 161
Cdd:COG0235   81 AIYRARPDVGAVVHTHSPYATALSALGE-----PLPPLeQTEAAAFLGDVPVVPYAGPGTEELAEAIAEALGDRPAVLLR 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 740843811 162 NHGPVVTGKDLRAAADNAEEMEDAARL-IFTLGDRPIRYLTDDEIAELR 209
Cdd:COG0235  156 NHGVVVWGKDLAEAFDRAEVLEEAARIqLLALALGGPLVLSDEEIDKLA 204
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 11-188 6.27e-60

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 185.44  E-value: 6.27e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   11 EEMVRLGASFFQRGYATGSAGNLSLLLPDGALLATPTGSCLGELQADRLSKVSLNGDWLS-GDKPSKEISFHRALYLNNP 89
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRLPGDGFLITPSGVDFGELTPEDLVVVDLDGNVVEgGLKPSSETPLHLAIYRARP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   90 ECKAVVHLHCTYLTALSCLQgldadNAIKPFTPYVVMRVGK-VPVVPYYRPGDERLAQDLAR-LAPTHRAFLLANHGPVV 167
Cdd:pfam00596  81 DAGAVVHTHSPYATALSLAK-----EGLPPITQEAADFLGGdIPIIPYYTPGTEELGERIAEaLGGDRKAVLLRNHGLLV 155

                         170       180
                  ....*....|....*....|.
gi 740843811  168 TGKDLRAAADNAEEMEDAARL 188
Cdd:pfam00596 156 WGKTLEEAFYLAEELERAAEI 176
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 13-188 7.22e-49

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 157.80  E-value: 7.22e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811    13 MVRLGASFFQRGYATGSAGNLSL-LLPDGALLATPTGSCLGELQADRLSKVSLNG---DWLSGDKPSKEISFHRALYLNN 88
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISArVGEEDLFLITPSGVDFGELTASDLVVVDLDGnvvEGGGGPKPSSETPLHLAIYRAR 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811    89 PECKAVVHLHCTYLTALSCLqgldADNAIKPFTPYVVMRVG-KVPVVPYYRPGD------ERLAQDLARLAPTHRAFLLA 161
Cdd:smart01007  81 PDVGAVVHTHSPYATALAAL----GKPLPLLPTEQAAAFLGgEIPYAPYAGPGTelaeegAELAEALAEALPDRPAVLLR 156

                          170       180
                   ....*....|....*....|....*..
gi 740843811   162 NHGPVVTGKDLRAAADNAEEMEDAARL 188
Cdd:smart01007 157 NHGLLVWGKTLEEAFDLAEELEEAAEI 183
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 20-193 3.82e-30

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 110.53  E-value: 3.82e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  20 FFQRGYATGSAGNLSLLLPD-GALLATPTGSCLGELQADRLSKVSLNGDWLSGDKPSKEISFHRALYLNNPECKAVVHLH 98
Cdd:cd00398   14 LDLYGWVTGTGGNVSARDRDrGYFLITPSGVDYEEMTASDLVVVDAQGKVVEGKKPSSETPLHLALYRARPDIGCIVHTH 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  99 CTYLTALSCLQGLDAdnaikPFTPY--VVMRVGKVPVVPYYRPGDE--RLAQDLARLAPTHRAFLLANHGPVVTGKDLRA 174
Cdd:cd00398   94 STHATAVSQLKEGLI-----PAGHTacAVYFTGDIPCTPYMTPETGedEIGTQRALGFPNSKAVLLRNHGLFAWGPTLDE 168

                        170       180
                 ....*....|....*....|
gi 740843811 175 AADNAEEMEDAARL-IFTLG 193
Cdd:cd00398  169 AFHLAVVLEVAAEIqLKALS 188
PRK08333 PRK08333
aldolase;
22-188 3.54e-28

aldolase;


Pssm-ID: 181393 [Multi-domain]  Cd Length: 184  Bit Score: 104.52  E-value: 3.54e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  22 QRGYATGSAGNLSLLLPDGALLATpTGSCLGELQADRLSKVSLNGDWLSGDKPSKEISFHRALYLNNPECKAVVHLHCTY 101
Cdd:PRK08333  17 ERGLTAAFGGNLSIRVGNLVFIKA-TGSVMDELTREQVAVIDLNGNQLSSVRPSSEYRLHLAVYRNRPDVRAIAHLHPPY 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811 102 LTALSCLqgLDADNAIkpFTPYVVMRVGKVPVVPYYRPGDERLAQDLARLAPTHRAFLLANHGPVVTGKDLRAAADNAEE 181
Cdd:PRK08333  96 SIVASTL--LEEELPI--ITPEAELYLKKIPILPFRPAGSVELAEQVAEAMKEYDAVIMERHGIVTVGRSLREAFYKAEL 171


                 ....*..
gi 740843811 182 MEDAARL 188
Cdd:PRK08333 172 VEESAKL 178
PRK06833 PRK06833
L-fuculose-phosphate aldolase;
7-205 5.33e-28

L-fuculose-phosphate aldolase;


Pssm-ID: 180717 [Multi-domain]  Cd Length: 214  Bit Score: 104.83  E-value: 5.33e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   7 QQAREEMVRLGASFFQRGYATGSAGNLSLLLPDGALLA-TPTGSCLGELQADRLSKVSLNGDWLSGD-KPSKEISFHRAL 84
Cdd:PRK06833   4 QKEREEIVAYGKKLISSGLTKGTGGNISIFNREQGLMAiTPSGIDYFEIKPEDIVIMDLDGKVVEGErKPSSELDMHLIF 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  85 YLNNPECKAVVHLHCTYLTALSCLqgldadNAIKPFTPYVVMRVGK-VPVVPYYRPGDERLAQDLARLAPTHRAFLLANH 163
Cdd:PRK06833  84 YRNREDINAIVHTHSPYATTLACL------GWELPAVHYLIAVAGPnVRCAEYATFGTKELAENAFEAMEDRRAVLLANH 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 740843811 164 GPVVTGKDLRAAADNAEEMEDAARLIF---TLGDRPIryLTDDEI 205
Cdd:PRK06833 158 GLLAGANNLKNAFNIAEEIEFCAEIYYqtkSIGEPKL--LPEDEM 200
PRK08087 PRK08087
L-fuculose-phosphate aldolase;
12-206 4.43e-25

L-fuculose-phosphate aldolase;


Pssm-ID: 181226 [Multi-domain]  Cd Length: 215  Bit Score: 97.50  E-value: 4.43e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  12 EMVRLGASffqrgyaTGSAGNLSLLLPDGaLLATPTGSCLGELQADRLSKVSLNGDWLSGDKPSKEISFHRALYLNNPEC 91
Cdd:PRK08087  16 EMTRLGLN-------QGTAGNVSVRYQDG-MLITPTGIPYEKLTESHIVFVDGNGKHEEGKLPSSEWRFHMAAYQTRPDA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  92 KAVVHLHCTYLTALSCLqgldadNAIKPFTPYVVMRVG--KVPVVPYYRPGDERLAQDLARLAPTHRAFLLANHGPVVTG 169
Cdd:PRK08087  88 NAVVHNHAVHCTAVSIL------NRPIPAIHYMIAAAGgnSIPCAPYATFGTRELSEHVALALKNRKATLLQHHGLIACE 161

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 740843811 170 KDLRAAADNAEEMEDAARLIFTLG--DRPIRYLTDDEIA 206
Cdd:PRK08087 162 VNLEKALWLAHEVEVLAQLYLKTLaiTDPVPVLSDEEIA 200
PRK08660 PRK08660
aldolase;
11-202 3.01e-22

aldolase;


Pssm-ID: 181527 [Multi-domain]  Cd Length: 181  Bit Score: 88.86  E-value: 3.01e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  11 EEMVRLGASFFQRGYATGSAGNLSLLLPDGaLLATPTGSCLGELQADRLSKVSLNGDwlsGDKP---SKEISFHRALYLN 87
Cdd:PRK08660   3 QEFARIGKKLFAHGLVSSHFGNISVRTGDG-LLITRTGSMLDEITEGDVIEVGIDDD---GSVDplaSSETPVHRAIYRR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  88 NPEcKAVVHLHCTYLTALSCLQGLdadnaIKPFTPYVVMRVGKVPVVPYyRPGDERLAQDLARLAPTHRAFLLANHGPVV 167
Cdd:PRK08660  79 TSA-KAIVHAHPPYAVALSLLEDE-----IVPLDSEGLYFLGTIPVVGG-DIGSGELAENVARALSEHKGVVVRGHGTFA 151

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 740843811 168 TGKDLRAAADNAEEMEDAARliftlgdrpIRYLTD 202
Cdd:PRK08660 152 IGKTLEEAYIYTSQLEHSCK---------VLYLVR 177
PRK06557 PRK06557
L-ribulose-5-phosphate 4-epimerase; Validated
 8-208 1.09e-21

L-ribulose-5-phosphate 4-epimerase; Validated


Pssm-ID: 235829 [Multi-domain]  Cd Length: 221  Bit Score: 88.53  E-value: 1.09e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   8 QAREEMVRLGASFFQRGYATGSAGNLSLLLPDGALLA-TPTGSCLGELQADRLSKVSLNGDWLSGD-KPSKEISFHRALY 85
Cdd:PRK06557  10 KLREEVCKLHLELPKYGLVVWTSGNVSARDPGTDLVViKPSGVSYDDLTPEDMVVVDLDGNVVEGDlKPSSDTASHLYVY 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  86 LNNPECKAVVHLHCTYLTALSCLQgldadnaiKPFTPYVVMRV----GKVPVVPYYRPGDERLAQDLARLAPTHR--AFL 159
Cdd:PRK06557  90 RHMPDVGGVVHTHSTYATAWAARG--------EPIPCVLTAMAdefgGPIPVGPFALIGDEAIGKGIVETLKGGRspAVL 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 740843811 160 LANHGPVVTGKDLRAAADNAEEMEDAARLIF---TLGDrPIRyLTDDEIAEL 208
Cdd:PRK06557 162 MQNHGVFTIGKDAEDAVKAAVMVEEVARTVHiarQLGE-PIP-IPQEEIDRL 211
PRK06357 PRK06357
hypothetical protein; Provisional
 7-190 2.10e-13

hypothetical protein; Provisional


Pssm-ID: 180541 [Multi-domain]  Cd Length: 216  Bit Score: 66.34  E-value: 2.10e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   7 QQAREEMVRLGASFFQRGYATGSAGNLSLLLPDGA----LLATPT---GSCLGELQADRLSKVSL-NGDWLSGD-KPSKE 77
Cdd:PRK06357   4 QKEREDLAKVVKTMFDRKETNAAGGNISVRMTAEKnkeyIIMTPTlmsEAKLCDLSPYQILVVDLnTGEVIEGVgRVTRE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  78 ISFHRALYLNNPECKAVVHLHCTYLTALSCLqGLDADNAIKpftpyVVMRVGKVPVVPYYRPGDERLAqDLARLAPTHR- 156
Cdd:PRK06357  84 INMHEAAYVANPKIKCVYHSHAKESMFWATL-GLEMPNLTE-----ATQKLGKIPTLPFAPATSPELA-EIVRKHLIELg 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 740843811 157 ------AFLLANHGPVVTGKDLRAAADNAEEMEDAARLIF 190
Cdd:PRK06357 157 dkavpsAFLLNSHGIVITDTSLHKAYDILETIEWNAYIAY 196
PRK09220 PRK09220
methylthioribulose 1-phosphate dehydratase;
3-175 3.72e-11

methylthioribulose 1-phosphate dehydratase;


Pssm-ID: 236415 [Multi-domain]  Cd Length: 204  Bit Score: 59.95  E-value: 3.72e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   3 MTTEQQAREeMVRLGASFFQRGYATGSAGNLSLLLPDGALLATPTGSCLGELQADRLSKVSLNGDWL-SGDKPSKEISFH 81
Cdd:PRK09220   1 MTLEELLQQ-LIAAGRWIGARGWVPATSGNMSVRLDEQHCAITVSGKDKGSLTAEDFLQVDIAGNAVpSGRKPSAETLLH 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  82 RALYLNNPECKAVVHLHCTYLTALSCLQGLDA-----DNAIKPFTPYVV--MRVgKVPVVpyyrPGDerlaQDLARLA-- 152
Cdd:PRK09220  80 TQLYRLFPEIGAVLHTHSVNATVLSRVEKSDAlvlegYELQKAFAGQTTheTAV-VVPIF----DND----QDIARLAar 150

                        170       180       190
                 ....*....|....*....|....*....|.
gi 740843811 153 --------PTHRAFLLANHGPVVTGKDLRAA 175
Cdd:PRK09220 151 vapyldaqPLRYGYLIRGHGLYCWGRDMAEA 181
PRK05874 PRK05874
L-fuculose-phosphate aldolase; Validated
 21-169 8.92e-10

L-fuculose-phosphate aldolase; Validated


Pssm-ID: 102036 [Multi-domain]  Cd Length: 217  Bit Score: 56.19  E-value: 8.92e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  21 FQRGYATGSAGNLSLLLPDGALLATPTGSCLGELQADRLSKVSLNGDWL---SGDKPSKEISFHRALYLNNPECKAVVHL 97
Cdd:PRK05874  19 LRRGLVEGTAGNISARRSDGNVVITPSSVDYAEMLLHDLVLVDAGGAVLhakDGRSPSTELNLHLACYRAFDDIGSVIHS 98

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 740843811  98 HCTYLTALSCL-QGLDAdnAIKPFTPYVvmrVGKVPVVPYYRPGDERLAQDLARLAPTHRAFLLANHGPVVTG 169
Cdd:PRK05874  99 HPVWATMFAVAhEPIPA--CIDEFAIYC---GGDVRCTEYAASGTPEVGRNAVRALEGRAAALIANHGLVAVG 166
PRK07490 PRK07490
hypothetical protein; Provisional
 79-207 1.06e-09

hypothetical protein; Provisional


Pssm-ID: 236031 [Multi-domain]  Cd Length: 245  Bit Score: 56.27  E-value: 1.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  79 SFHRALYLNNPECKAVVHLHCTYLTALSCLqgldADNAIKPFTPYVVMRVGKVPVVPYYRP-GDERLAQDLARLAPTHRA 157
Cdd:PRK07490  86 AIHGQIHRRLPHARCVMHVHSVYATALACL----ADPTLPPIDQNTARFFNRVAVDTLYGGmALEEEGERLAGLLGDKRR 161

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 740843811 158 FLLANHGPVVTGKDLRAAADNAEEMEDAARLIFTL--GDRPIRYLTdDEIAE 207
Cdd:PRK07490 162 LLMGNHGVLVTGDTVAEAFDDLYYFERACQTYITAlsTGQPLRVLS-DAVAE 212
sgaE PRK12348
L-ribulose-5-phosphate 4-epimerase; Reviewed
 24-188 1.16e-09

L-ribulose-5-phosphate 4-epimerase; Reviewed


Pssm-ID: 183460  Cd Length: 228  Bit Score: 55.96  E-value: 1.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  24 GYATGSAGNLSLL-LPDGALLATPTGSCLGELQADRLSKVSLNGDWLSGD-KPSKEISFHRALYLNNPECKAVVHLHCTY 101
Cdd:PRK12348  19 GLVTFTWGNVSAIdRERGLVVIKPSGVAYETMKADDMVVVDMSGKVVEGEyRPSSDTATHLELYRRYPSLGGIVHTHSTH 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811 102 LTALSclqglDADNAIKPF-TPYVVMRVGKVPVV----------PYYRPGDERLAQDLARLAPTHR-AFLLANHGPVVTG 169
Cdd:PRK12348  99 ATAWA-----QAGLAIPALgTTHADYFFGDIPCTrglseeevqgEYELNTGKVIIETLGNAEPLHTpGIVVYQHGPFAWG 173

                        170
                 ....*....|....*....
gi 740843811 170 KDLRAAADNAEEMEDAARL 188
Cdd:PRK12348 174 KDAHDAVHNAVVMEEVAKM 192
PRK03634 PRK03634
rhamnulose-1-phosphate aldolase; Provisional
 70-208 4.54e-08

rhamnulose-1-phosphate aldolase; Provisional


Pssm-ID: 179615 [Multi-domain]  Cd Length: 274  Bit Score: 51.91  E-value: 4.54e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  70 SGDKPSKEISFHRALYLN-----NPECKAVVHLHCTYLTALSCLQGLDADNaikpFTP---------YVVMRVGkVPVVP 135
Cdd:PRK03634 110 NGGKPTSELPAHLMSHIArlkatNGKDRVIMHCHATNLIALTYVLELDEAV----FTRtlwemstecLVVFPDG-VGIVP 184

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 740843811 136 YYRPGDERLAQDLARLAPTHRAFLLANHGPVVTGKDLRAAADNAEEMEDAARL---IFTLGDRPiRYLTDDEIAEL 208
Cdd:PRK03634 185 WMVPGTDEIGQATAEKMQKHDLVLWPKHGVFGSGPTLDEAFGLIDTAEKSAEIyvkVLSMGGMK-QTITDEELIAL 259
PRK06486 PRK06486
aldolase;
8-186 2.22e-07

aldolase;


Pssm-ID: 235814  Cd Length: 262  Bit Score: 49.71  E-value: 2.22e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   8 QAREEM---VRLGAsffQRGYATGSAGNLSLLLP--DGALLATPTGSCLGELQADRLSKVSLNGDWLSGDKPSKEISF-- 80
Cdd:PRK06486  26 QARVDLaacFRAAA---RHGLEEGICNHFSAVLPghDDLFLVNPYGYAFSEITASDLLICDFDGNVLAGRGEPEATAFfi 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  81 HRALYLNNPECKAVVHLHCTYLTALSCLQG----LDADNAIKPFtpyvvmrvGKVPVVPYYRpG---DERLAQDLARLAP 153
Cdd:PRK06486 103 HARIHRAIPRAKAAFHTHMPYATALSLTEGrpltTLGQTALKFY--------GRTAVDEDYN-GlalDAAEGDRIARAMG 173

                        170       180       190
                 ....*....|....*....|....*....|...
gi 740843811 154 THRAFLLANHGPVVTGKDLRAAADNAEEMEDAA 186
Cdd:PRK06486 174 DADIVFLKNHGVMVCGPRIAEAWDDLYYLERAC 206
araD PRK08193
L-ribulose-5-phosphate 4-epimerase AraD;
46-192 9.03e-07

L-ribulose-5-phosphate 4-epimerase AraD;


Pssm-ID: 236181  Cd Length: 231  Bit Score: 47.91  E-value: 9.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  46 PTGSCLGELQADRLSKVSLNGDWLSGD-KPSKEISFHRALYLNNPECKAVVHLHCTYLTALSclQ-GLD--------ADN 115
Cdd:PRK08193  43 PSGVDYDKMTAEDMVVVDLEGNVVEGKlKPSSDTPTHLVLYKAFPEIGGIVHTHSRHATAWA--QaGRDipalgtthADY 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811 116 aikpFTpyvvmrvGKVPVVPYYRpgDERLAQD--------------LARLAPTH-RAFLLANHGPVVTGKDLRAAADNAE 180
Cdd:PRK08193 121 ----FY-------GDIPCTRKMT--DEEINGEyewetgkvivetfeKRGIDPAAvPGVLVHSHGPFTWGKDAEDAVHNAV 187

                        170
                 ....*....|...
gi 740843811 181 EMEDAARL-IFTL 192
Cdd:PRK08193 188 VLEEVAKMaYFTR 200
PRK07090 PRK07090
class II aldolase/adducin domain protein; Provisional
 21-188 5.36e-06

class II aldolase/adducin domain protein; Provisional


Pssm-ID: 180832  Cd Length: 260  Bit Score: 45.78  E-value: 5.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  21 FQRGYATGSAGNLSLLLPD-GALLATPTGSCLGELQADRLSKVSLNGDWLSGDK-PSKEISFHRALYLNNPECKAVVHLH 98
Cdd:PRK07090  43 FDAGHDSGLAGQITARAEApGTYYTQRLGLGFDEITASNLLLVDEDLNVLDGEGmPNPANRFHSWIYRARPDVNCIIHTH 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  99 CTYLTALSCLQgldadnaikpfTPYVVMR------------VGKVPVVPYyrpGDER---LAQDLArlapTHRAFLLANH 163
Cdd:PRK07090 123 PPHVAALSMLE-----------VPLVVSHmdtcplyddcafLKDWPGVPV---GNEEgeiISAALG----DKRAILLSHH 184

                        170       180
                 ....*....|....*....|....*
gi 740843811 164 GPVVTGKDLRAAADNAEEMEDAARL 188
Cdd:PRK07090 185 GQLVAGKSIEEACVLALLIERAARL 209
PRK06208 PRK06208
class II aldolase/adducin family protein;
6-187 4.95e-05

class II aldolase/adducin family protein;


Pssm-ID: 235743  Cd Length: 274  Bit Score: 43.05  E-value: 4.95e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811   6 EQQAREEmvRLGASF--FQR-GYATGSAGNLSLL---LPDgALLATPTGSCLGELQADRLSKVSLNGDWLSGDKPSKEIS 79
Cdd:PRK06208  39 ERLHRKQ--RLAAAFrlFARfGFDEGLAGHITARdpeLPD-HFWVNPLGVHFSQIKVSDLLLVDHDGEVVEGDRPLNRAA 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740843811  80 F--HRALYLNNPECKAVVHLHCTYLTALSCL-QGLDA----------DNAIkpFTPY--VVMRVGKvpvvpyyrpGDeRL 144
Cdd:PRK06208 116 FaiHSAIHEARPDVVAAAHTHSTYGKAWSTLgRPLDPitqdacafyeDHAL--FDDFtgVVVDTSE---------GR-RI 183

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 740843811 145 AQDLArlapTHRAFLLANHGPVVTGKDLRAAADNAEEMEDAAR 187
Cdd:PRK06208 184 AAALG----THKAVILQNHGLLTVGPSVDAAAWWFIALERACQ 222
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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