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Conserved domains on  [gi|740851067|ref|WP_038636320|]
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MULTISPECIES: glutamate/aspartate:proton symporter GltP [Citrobacter]

Protein Classification

proton/glutamate symporter( domain architecture ID 10013774)

proton/glutamate symporter, similar to E.coli GltP, imports glutamate coupled with the import of H+; belongs to the dicarboxylate/amino acid:cation symporter family

Gene Ontology:  GO:0005280|GO:0022857

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
1-437 0e+00

glutamate/aspartate:proton symporter; Provisional


:

Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 778.56  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067   1 MKNLKVSLAWQILIAMVLGILLGSYLHYHSDSREWLIVNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRI 80
Cdd:PRK11283   1 MKNIKFSLAWQILIALVLGILLGAYLHYHSDSRDWLVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  81 GAKTIIYFEVITTVAIILGITLANVFQPGTGVDMSQLATVDISKYQSTTAEVQSHAHGLMGTILSLVPTNIVASMAKGDM 160
Cdd:PRK11283  81 GAKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATVDISKYQSTTEEVQSHSHGLMGTILSLIPTNIFASMAKGEM 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 161 LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVHFA 240
Cdd:PRK11283 161 LPIIFFSVLFGLGLSSLPATHREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVYFA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 241 ILFFALVVLGIVARICGLSIWILIRILKDELILAYSTASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQ 320
Cdd:PRK11283 241 ILFFALVVLGIVARLCGLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTLYQ 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 321 SIAAIFIAQLYGIDLSLWQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG 400
Cdd:PRK11283 321 SIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG 400
                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 740851067 401 NALAVLVIAKWEHKFDRKKALAYERDVLGKFDKTANQ 437
Cdd:PRK11283 401 NALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTADQ 437
 
Name Accession Description Interval E-value
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
1-437 0e+00

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 778.56  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067   1 MKNLKVSLAWQILIAMVLGILLGSYLHYHSDSREWLIVNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRI 80
Cdd:PRK11283   1 MKNIKFSLAWQILIALVLGILLGAYLHYHSDSRDWLVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  81 GAKTIIYFEVITTVAIILGITLANVFQPGTGVDMSQLATVDISKYQSTTAEVQSHAHGLMGTILSLVPTNIVASMAKGDM 160
Cdd:PRK11283  81 GAKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATVDISKYQSTTEEVQSHSHGLMGTILSLIPTNIFASMAKGEM 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 161 LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVHFA 240
Cdd:PRK11283 161 LPIIFFSVLFGLGLSSLPATHREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVYFA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 241 ILFFALVVLGIVARICGLSIWILIRILKDELILAYSTASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQ 320
Cdd:PRK11283 241 ILFFALVVLGIVARLCGLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTLYQ 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 321 SIAAIFIAQLYGIDLSLWQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG 400
Cdd:PRK11283 321 SIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG 400
                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 740851067 401 NALAVLVIAKWEHKFDRKKALAYERDVLGKFDKTANQ 437
Cdd:PRK11283 401 NALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTADQ 437
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
4-424 1.58e-163

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 466.13  E-value: 1.58e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067   4 LKVSLAWQILIAMVLGILLGSYLHYhsdsrewLIVNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRIGAK 83
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPE-------LVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLGDLKKLGRIGGK 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  84 TIIYFEVITTVAIILGITLANVFQPGTGVDMSQLATVDISKyqsttaevqSHAHGLMGTILSLVPTNIVASMAKGDMLPI 163
Cdd:COG1301   74 TLLYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEA---------AEAPSLLDFLLNIIPSNIFEAFAEGNMLQI 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 164 IFFSVLFGLGLSSLPAtHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVHFAILF 243
Cdd:COG1301  145 IFFAILFGIALAALGE-KGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKYGLDALGSLGKLVLTVYLALLL 223
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 244 FALVVLGIVAR-ICGLSIWILIRILKDELILAYSTASSESVLPRIIEKM-EAYGAPASITSFVVPTGYSFNLDGSTLYQS 321
Cdd:COG1301  224 HLFVVLPLILRlLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAeEKLGVSKSVASFVLPLGATINMDGTAIYQA 303
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 322 IAAIFIAQLYGIDLSLWQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGN 401
Cdd:COG1301  304 VAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGD 383
                        410       420
                 ....*....|....*....|...
gi 740851067 402 ALAVLVIAKWEHKFDRKKALAYE 424
Cdd:COG1301  384 AVATVVVAKWEGELDREKLNAAL 406
SDF pfam00375
Sodium:dicarboxylate symporter family;
8-411 1.64e-118

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 351.05  E-value: 1.64e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067    8 LAWQILIAMVLGILLGSYLHYhsdsrewlIVNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRIGAKTIIY 87
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPE--------LAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLGDGKKLGKLGGKTLLY 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067   88 FEVITTVAIILGITLANVFQPGTGVDMSQLATVDISKyqsttaevqSHAHGLMGTILSLVPTNIVASMAKGDMLPIIFFS 167
Cdd:pfam00375  73 FLVTTAIAALIGLLVANVFQPGSGLALIAASLKEAKA---------AEAPSLLDFILNIIPSNIFEALAEGNVLAVIVFA 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  168 VLFGLGLSSLPaTHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVHFAILFFALV 247
Cdd:pfam00375 144 ILFGIALAALG-EKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGTYGLGILSSLAKFLLVVYLGLAIHLLI 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  248 VLGIVAR-ICGLSIWILIRILKDELILAYSTASSESVLPRIIEKME-AYGAPASITSFVVPTGYSFNLDGSTLYQSIAAI 325
Cdd:pfam00375 223 VYPLLIKfLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEkNLGVSESIASFVLPLGATINMDGTAIYLAVAAI 302
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  326 FIAQLYGIDLSLWQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAV 405
Cdd:pfam00375 303 FIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAA 382

                  ....*.
gi 740851067  406 LVIAKW 411
Cdd:pfam00375 383 VIVAKL 388
 
Name Accession Description Interval E-value
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
1-437 0e+00

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 778.56  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067   1 MKNLKVSLAWQILIAMVLGILLGSYLHYHSDSREWLIVNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRI 80
Cdd:PRK11283   1 MKNIKFSLAWQILIALVLGILLGAYLHYHSDSRDWLVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  81 GAKTIIYFEVITTVAIILGITLANVFQPGTGVDMSQLATVDISKYQSTTAEVQSHAHGLMGTILSLVPTNIVASMAKGDM 160
Cdd:PRK11283  81 GAKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATVDISKYQSTTEEVQSHSHGLMGTILSLIPTNIFASMAKGEM 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 161 LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVHFA 240
Cdd:PRK11283 161 LPIIFFSVLFGLGLSSLPATHREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVYFA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 241 ILFFALVVLGIVARICGLSIWILIRILKDELILAYSTASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQ 320
Cdd:PRK11283 241 ILFFALVVLGIVARLCGLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTLYQ 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 321 SIAAIFIAQLYGIDLSLWQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG 400
Cdd:PRK11283 321 SIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG 400
                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 740851067 401 NALAVLVIAKWEHKFDRKKALAYERDVLGKFDKTANQ 437
Cdd:PRK11283 401 NALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTADQ 437
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
4-424 1.58e-163

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 466.13  E-value: 1.58e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067   4 LKVSLAWQILIAMVLGILLGSYLHYhsdsrewLIVNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRIGAK 83
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPE-------LVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLGDLKKLGRIGGK 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  84 TIIYFEVITTVAIILGITLANVFQPGTGVDMSQLATVDISKyqsttaevqSHAHGLMGTILSLVPTNIVASMAKGDMLPI 163
Cdd:COG1301   74 TLLYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEA---------AEAPSLLDFLLNIIPSNIFEAFAEGNMLQI 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 164 IFFSVLFGLGLSSLPAtHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVHFAILF 243
Cdd:COG1301  145 IFFAILFGIALAALGE-KGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKYGLDALGSLGKLVLTVYLALLL 223
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 244 FALVVLGIVAR-ICGLSIWILIRILKDELILAYSTASSESVLPRIIEKM-EAYGAPASITSFVVPTGYSFNLDGSTLYQS 321
Cdd:COG1301  224 HLFVVLPLILRlLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAeEKLGVSKSVASFVLPLGATINMDGTAIYQA 303
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 322 IAAIFIAQLYGIDLSLWQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGN 401
Cdd:COG1301  304 VAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGD 383
                        410       420
                 ....*....|....*....|...
gi 740851067 402 ALAVLVIAKWEHKFDRKKALAYE 424
Cdd:COG1301  384 AVATVVVAKWEGELDREKLNAAL 406
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
1-420 1.94e-142

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 413.53  E-value: 1.94e-142
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067   1 MKNLKVSLAWQILIAMVLGILLGsylHYHSDSREwlivnLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRI 80
Cdd:PRK01663   2 KKPLYKSLYFQVLVAIIIGILLG---HFYPELGA-----QMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMGDMKKVGRV 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  81 GAKTIIYFEVITTVAIILGITLANVFQPGTG--VDMSQLATVDISKYQSttaevQSHAHGLMGTILSLVPTNIVASMAKG 158
Cdd:PRK01663  74 GGKALLYFEIVSTIALIIGLIVVNVVQPGAGmnIDPATLDAKAVAQYAA-----QAHEQGTVDFLMDIIPTTVVGAFASG 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 159 DMLPIIFFSVLFGLGLSSLPATHRePLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVH 238
Cdd:PRK01663 149 DILQVLLFAVLFGFALARLGEKGK-PVFDFIESLSHVLFGIVNMIMKLAPIGAFGAMAFTIGKYGVGSLVQLGQLIGCFY 227
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 239 FAILFFALVVLGIVARICGLSIWILIRILKDELILAYSTASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTL 318
Cdd:PRK01663 228 ITCILFVFVVLGAIARLTGFSIFKFIRYIKEELLIVLGTSSSESALPRMMEKMEKLGCKKSVVGLVIPTGYSFNLDGTSI 307
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 319 YQSIAAIFIAQLYGIDLSLWQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVG-IPLEGLAFIAGVDRILDMARTALN 397
Cdd:PRK01663 308 YLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTN 387
                        410       420
                 ....*....|....*....|...
gi 740851067 398 VVGNALAVLVIAKWEHKFDRKKA 420
Cdd:PRK01663 388 LIGNGVATVVVAKWEKELDREKL 410
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
1-420 7.54e-119

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 353.20  E-value: 7.54e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067   1 MKNLKVSLAWQILIAMVLGILLGSYLHYHSDSrewlivnlLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRI 80
Cdd:PRK13027   1 MKKFLRSLFGQVVIALVLGVALGAFFPHFAES--------LKPLGDGFIKLIKMLIGPIVFCVVVSGIAGAGDLKKVGRV 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  81 GAKTIIYFEVITTVAIILGITLANVFQPGTG--VDMSQLATVDISKYQSTTAEVqshaHGLMGTILSLVPTNIVASMAKG 158
Cdd:PRK13027  73 GLKAVIYFEVMTTIALVIGLVLAYLTGPGVGmnIDLRSLDAASLAGYAKNAQSL----KGTAGFLLKLIPTTAVDAFAKG 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 159 DMLPIIFFSVLFGLGLSSLPATHRePLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVH 238
Cdd:PRK13027 149 DILQVLLFSVLFGSALSLLGERAK-RVNRLIDELSHVLFRIMGFIIKLAPLGVLGAIAFTTGKYGVGSLKQLGMLVAVFY 227
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 239 FAILFFALVVLGIVARICGLSIWILIRILKDELILAYSTASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTL 318
Cdd:PRK13027 228 LTCFVFVVVVLGAVMRLAGFSVFKLIRYLREELLIVLGTASSDAVLPQVMRKLEHMGIKDSTVGLVIPTGYSFNLDGFSI 307
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 319 YQSIAAIFIAQLYGIDLSLWQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVG-IPLEGLAFIAGVDRILDMARTALN 397
Cdd:PRK13027 308 YLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTN 387
                        410       420
                 ....*....|....*....|...
gi 740851067 398 VVGNALAVLVIAKWEHKFDRKKA 420
Cdd:PRK13027 388 LIGNCVATVVVAVWENDIDRARA 410
SDF pfam00375
Sodium:dicarboxylate symporter family;
8-411 1.64e-118

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 351.05  E-value: 1.64e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067    8 LAWQILIAMVLGILLGSYLHYhsdsrewlIVNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRIGAKTIIY 87
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPE--------LAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLGDGKKLGKLGGKTLLY 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067   88 FEVITTVAIILGITLANVFQPGTGVDMSQLATVDISKyqsttaevqSHAHGLMGTILSLVPTNIVASMAKGDMLPIIFFS 167
Cdd:pfam00375  73 FLVTTAIAALIGLLVANVFQPGSGLALIAASLKEAKA---------AEAPSLLDFILNIIPSNIFEALAEGNVLAVIVFA 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  168 VLFGLGLSSLPaTHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVHFAILFFALV 247
Cdd:pfam00375 144 ILFGIALAALG-EKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGTYGLGILSSLAKFLLVVYLGLAIHLLI 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  248 VLGIVAR-ICGLSIWILIRILKDELILAYSTASSESVLPRIIEKME-AYGAPASITSFVVPTGYSFNLDGSTLYQSIAAI 325
Cdd:pfam00375 223 VYPLLIKfLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEkNLGVSESIASFVLPLGATINMDGTAIYLAVAAI 302
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  326 FIAQLYGIDLSLWQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAV 405
Cdd:pfam00375 303 FIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAA 382

                  ....*.
gi 740851067  406 LVIAKW 411
Cdd:pfam00375 383 VIVAKL 388
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
1-419 7.48e-35

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 134.57  E-value: 7.48e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067   1 MKNLKVSLAWQILIAMVLGILLGSYLHYH--------SDSREWL-IVnllspaGDIFIHLIKMIVVPIVISTLIVGIAGV 71
Cdd:COG1823   23 MQKKHVSFSKRVFTGLGLGILFGLILQLIygagspviKQSIDWFnIV------GNGYVRLLQMIVMPLVFVSILSAITKL 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  72 GDAKQLGRIGAKTIIYFEVITTVAIILGITLANVFqpgtGVDMSQLA-----TVDISKYQSTTAEVQSHAhgLMGTILSL 146
Cdd:COG1823   97 KNASSLGKISGLIIGILLGTTAIAALVGILVALLF----GLTAEGLTqgaaeTARGEALEERLGEVEDLS--LPQQILSF 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 147 VPTNIVASMAKGDMLPII---FFSVLFG---LGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVTVA 220
Cdd:COG1823  171 IPTNPFADLTGARPTSTIavvIFAAFLGiaaLGLRRKKPEQAETFLKGIDALQAIVMRLVRLVLRLTPYGVLALMTKVVA 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 221 NFGFASLWPLAKLVLLVHFAILFFALVVLGIVArICGLSIWILIRILKDELILAYSTASSESVLPRIIE-KMEAYGAPAS 299
Cdd:COG1823  251 TSDFADILNLGKFVVASYVALIIMFIVHLLLLA-LAGLNPLTYFKKVWPVLTFAFTSRSSAGTIPLNIEtQTKRLGVPEG 329
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 300 ITSFVVPTGYSFNLDG-STLYQSIAAIFIAQLYGID-LSLWQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLE 377
Cdd:COG1823  330 IANFAASFGATIGQNGcAGIYPAMLAVMIAPTVGINpLDPSFILTLIAVVTISSFGVAGVGGGATFAALIVLSAMGLPVA 409
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|..
gi 740851067 378 GLAFIAGVDRILDMARTALNVVGNALAVLVIAKWEHKFDRKK 419
Cdd:COG1823  410 LAGLLISIEPLIDMGRTALNVSGSMTAGTVTSRLLGQLDKDI 451
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
4-397 9.87e-18

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 84.53  E-value: 9.87e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067   4 LKVSLAWQILIAMVLGILLGSYLHYHsdsreWLIVNLLspaGDIFIHLIKMiVVPIVISTLIvgIAGVGDAKQLGRIGAK 83
Cdd:PRK13628  12 ARGSLVKQILIGLVLGILLALLSPPA-----AEAVGLL---GTLFVGALKA-VAPILVFVLV--MASIANHKKGQKTNIR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067  84 TIIYFEVITTVAIILGITLANVFQPGTGVdmsqLATVDISkyqstTAEVQSHAHGLMGTILSLVpTNIVASMAKGDMLPI 163
Cdd:PRK13628  81 PILVLYLLGTFLAALVAVVASFLFPSTLV----LVASAAD-----ISPPQGIVEVLKTLLLSLV-DNPINALLNANYIGI 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 164 IFFSVLFGLGLSSLPATHReplvTVFRSISETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVHFAILF 243
Cdd:PRK13628 151 LAWAIGLGLALRHASDTTK----NVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAETGFSALAGYAQLLAVLVGCMLF 226
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 244 FALVVLGIVaricglsIWILIR---------ILKDELILAYSTASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLD 314
Cdd:PRK13628 227 VALVVNPLI-------VFWKIRrnpyplvftCLRESGVTAFFTRSSAANIPVNMALCEKLGLDEDTYSVSIPLGATINMA 299
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 315 GSTLYQSIAAIFIAQLYGIDLSLWQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLE------GLAFIAGVdrI 388
Cdd:PRK13628 300 GAAITITVLTLAAVHTLGIPVDLPTALLLSVVAAISACGASGVAGGSLLLIPLACSLFGISNDiamqvvAVGFIIGV--L 377

                 ....*....
gi 740851067 389 LDMARTALN 397
Cdd:PRK13628 378 QDSAETALN 386
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
152-419 8.66e-08

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 53.52  E-value: 8.66e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 152 VASMAKGDMLPIIFFSVLFGLGLSSLPATHREplvtVFRSISETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLA 231
Cdd:PRK14695  53 VNALLTANYIGILSWAVIFGIAMREASKNSKE----LLKTIADVTSKIVEWIINLAPFGILGLVFKTISDKGVGSLANYG 128
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 232 KLVLLVHFAILFFALVVLGIVA-----RICGLSIWILIRIlkdELILAYSTASSESVLPRIIEKMEAYGAPASITSFVVP 306
Cdd:PRK14695 129 ILLVLLVTTMLFVAPVVNPLIAfffmrRNPYPLVWNCLRV---SGVTAFFTRSSATNIPVNMKLCHDLGLNPDTYSVSIP 205
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740851067 307 TGYSFNLDGSTLYQSIAAIFIAQLYGIDLSLWQEIVLVLTLMVTSKGIAGVPGVSFVV------LLATLGSVGIPLEGLA 380
Cdd:PRK14695 206 LGSTINMAGVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLipvacsLFGISNDIAIQIVGVG 285
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 740851067 381 FIAGVdrILDMARTALNvvgNALAVLVIAKWEHKFDRKK 419
Cdd:PRK14695 286 FVIGV--IQDSCETALN---SSTDVLFTAVAEYAATRKK 319
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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