|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
7-842 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1605.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 7 EITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVY 86
Cdd:PRK05560 4 RIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAVY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 87 DTIVRMAQPFSLRYTLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMPTKIPNL 166
Cdd:PRK05560 84 DALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 167 LVNGASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKIYIRARA 246
Cdd:PRK05560 164 LVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMRAKA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 247 EVEVDpkNGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEIKRDAVGEVVLNNLYSQTQL 326
Cdd:PRK05560 244 EIEEI--KGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLYKHTQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 327 QVSFGINMVALHHGQPKIMPLKDILAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEA 406
Cdd:PRK05560 322 QTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPAEA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 407 KAGLIAqawdlgnvkamlegagddaarpewlepefgirdgKYWLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLTQIA 486
Cdd:PRK05560 402 KEGLME----------------------------------RFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIA 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 487 ELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKG 566
Cdd:PRK05560 448 DLKDILASPERLLEIIKEELLEIKEKFGDPRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKG 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 567 KSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREYEEGVNV 646
Cdd:PRK05560 528 VSGAKTKEDDFVEHLFVASTHDTLLFFTNRGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYL 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 647 FMATASGTVKKTALTEFSRPRTAGIIAVNLNEGDELIGVDLTAGKDEVMLFSAQGKVVRFKEDAVRPMGRTATGVRGIRL 726
Cdd:PRK05560 608 FFATKNGTVKKTSLSEFSNIRSNGIIAINLDEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIKL 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 727 GEGDSVVSLIVPRGEGA-ILTATQNGYGKRTAVEEYPTKSRATKGVISIKVTDRNGPVVGAVQVDDADQIMMITDAGTLV 805
Cdd:PRK05560 688 REGDEVVSMDVVREDSQeILTVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLI 767
|
810 820 830
....*....|....*....|....*....|....*..
gi 742382571 806 RTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEP 842
Cdd:PRK05560 768 RTRVSEISITGRNTQGVRLIRLDEGDKVVSVARVAEE 804
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-836 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1494.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 1 MSDL--AREITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYH 78
Cdd:COG0188 1 MSDPppAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 79 PHGDSAVYDTIVRMAQPFSLRYTLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDV 158
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 159 MPTKIPNLLVNGASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRG 238
Cdd:COG0188 161 LPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 239 KIYIRARAEVEvDPKNGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEIKRDAVGEVVLN 318
Cdd:COG0188 241 SIRVRAKAEIE-ELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLN 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 319 NLYSQTQLQVSFGINMVALHHGQPKIMPLKDILAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIR 398
Cdd:COG0188 320 QLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIR 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 399 RAPTPAEAKAGLIAqawdlgnvkamlegagddaarpewlepefgirdgKYWLTEQQAQAILDLRLQKLTGLEHEKLLDEY 478
Cdd:COG0188 400 ASKDPDEAKEALME----------------------------------RFGLSEIQAEAILDMRLRRLTGLEREKIEDEY 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 479 KELLTQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYE 558
Cdd:COG0188 446 AELLKEIAELEDILASEERLLKIIKEELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYR 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 559 AQRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVR 638
Cdd:COG0188 526 AQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVK 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 639 EYEEGVNVFMATASGTVKKTALTEFSRPRTAGIIAVNLNEGDELIGVDLTAGKDEVMLFSAQGKVVRFKEDAVRPMGRTA 718
Cdd:COG0188 606 EFDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTA 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 719 TGVRGIRLGEGDSVVSLIVPRGEGAILTATQNGYGKRTAVEEYPTKSRATKGVISIKVTDRNGPVVGAVQVDDADQIMMI 798
Cdd:COG0188 686 RGVRGIRLKEGDEVVGMAVVDEEDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLI 765
|
810 820 830
....*....|....*....|....*....|....*...
gi 742382571 799 TDAGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGL 836
Cdd:COG0188 766 TSSGQLIRTPVSDIRVTGRNTQGVRLIRLDEGDKVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
8-841 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1398.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 8 ITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYD 87
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 88 TIVRMAQPFSLRYTLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMPTKIPNLL 167
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 168 VNGASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKIYIRARAE 247
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 248 VEVDPKnGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEIKRDAVGEVVLNNLYSQTQLQ 327
Cdd:TIGR01063 241 IEEDSK-GREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQLQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 328 VSFGINMVALHHGQPKIMPLKDILAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEAK 407
Cdd:TIGR01063 320 VSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 408 AGLIAQawdlgnvkamlegagddaarpewlepefgirdgkYWLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLTQIAE 487
Cdd:TIGR01063 400 TRLVER----------------------------------FSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIAD 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 488 LLHILGSADRLMEVIREELELIRDQFGDERRTEITAN-SADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKG 566
Cdd:TIGR01063 446 LEDILASEERVLEIIREELEEIKEQFGDPRRTEIVYDeSEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKG 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 567 KSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREYEEGVNV 646
Cdd:TIGR01063 526 VSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYL 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 647 FMATASGTVKKTALTEFSRPRTAGIIAVNLNEGDELIGVDLTAGKDEVMLFSAQGKVVRFKEDAVRPMGRTATGVRGIRL 726
Cdd:TIGR01063 606 FFATKNGVVKKTSLTEFSNIRSNGIIAIKLDDGDELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKL 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 727 GEGDSVVSLIVPRGEGAILTATQNGYGKRTAVEEYPTKSRATKGVISIKVTDRNGPVVGAVQVDDADQIMMITDAGTLVR 806
Cdd:TIGR01063 686 KNEDFVVSLLVVSEESYLLIVTENGYGKRTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIR 765
|
810 820 830
....*....|....*....|....*....|....*
gi 742382571 807 TRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAE 841
Cdd:TIGR01063 766 TSVQDVSEQGRNTQGVRLIRLDEDDKLVSVSKVAK 800
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
30-507 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 721.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 30 VGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYTLVDGQGNF 109
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 110 GSIDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGASGIAVGMATNIPPHNLTE 189
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 190 VINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKIYIRARAEVEVDPknGRETIIVHEIPYQVN 269
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDE--GRNTIEITELPYQVN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 270 KARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEIKRDAVGEVVLNNLYSQTQLQVSFGINMVALHH-GQPKIMPLK 348
Cdd:cd00187 239 KAKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDPnGRPKKLNLK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 349 DILAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAptpAEAKAGLIAQAWDLGnvkamlegag 428
Cdd:cd00187 319 EILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELEKLG---------- 385
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 742382571 429 ddaarpewlepefgirdgkywLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLTQIAELLHILGSADRLMEVIREELE 507
Cdd:cd00187 386 ---------------------FSEIQADAILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELD 443
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
11-499 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 664.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 11 VNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIV 90
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 91 RMAQPFSLRYTLVDGQGNFGSI-DGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMPTKIPNLLVN 169
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 170 GASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINgrrgieeayrtGRGKIYIRARAEVE 249
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 250 vdpknGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDES-DKDGMRIVIEIKRDAVGEVVLNNLYSQTQLQV 328
Cdd:smart00434 230 -----DDNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQT 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 329 SFGINMVALH-HGQPKIMPLKDILAAFVRHRREVVTRRTIFELRKAR-DRAHILEALAIALANIDPIIELIRRAPTPA-E 405
Cdd:smart00434 305 TFSINMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDLAkE 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 406 AKAGLIAqawdlgnvkamlegagddaarpewlepefgirdgKYWLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLTQI 485
Cdd:smart00434 385 AKEKLME----------------------------------RFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEI 430
|
490
....*....|....
gi 742382571 486 AELLHILGSADRLM 499
Cdd:smart00434 431 EDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
32-507 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 628.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 32 RALPDVRDGLKPVHRRVLYAMNVLGNDwNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYTLVDGQGNFGS 111
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFELLNL-DKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 112 -IDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGASGIAVGMATNIPPHNLTEV 190
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 191 INGCLAYIDDEDISIegLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKIYIRARAEVEVdpkngRETIIVHEIPYQVNK 270
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED-----RKTIVITELPYGVWT 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 271 ARLIEKIAELVKEKRVEGISALRDESDKdGMRIVIEIKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMPLKDI 350
Cdd:pfam00521 233 SDLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 351 LAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEAKAGLIAQawdlgnvkamlegagdd 430
Cdd:pfam00521 312 LKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE----------------- 374
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 742382571 431 aarpewlepefgirdgkywLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLTQIAELLHILGSADRLMEVIREELE 507
Cdd:pfam00521 375 -------------------LSEIQADYLLDMRLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
7-842 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1605.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 7 EITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVY 86
Cdd:PRK05560 4 RIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAVY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 87 DTIVRMAQPFSLRYTLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMPTKIPNL 166
Cdd:PRK05560 84 DALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 167 LVNGASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKIYIRARA 246
Cdd:PRK05560 164 LVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMRAKA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 247 EVEVDpkNGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEIKRDAVGEVVLNNLYSQTQL 326
Cdd:PRK05560 244 EIEEI--KGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLYKHTQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 327 QVSFGINMVALHHGQPKIMPLKDILAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEA 406
Cdd:PRK05560 322 QTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPAEA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 407 KAGLIAqawdlgnvkamlegagddaarpewlepefgirdgKYWLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLTQIA 486
Cdd:PRK05560 402 KEGLME----------------------------------RFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIA 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 487 ELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKG 566
Cdd:PRK05560 448 DLKDILASPERLLEIIKEELLEIKEKFGDPRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKG 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 567 KSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREYEEGVNV 646
Cdd:PRK05560 528 VSGAKTKEDDFVEHLFVASTHDTLLFFTNRGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYL 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 647 FMATASGTVKKTALTEFSRPRTAGIIAVNLNEGDELIGVDLTAGKDEVMLFSAQGKVVRFKEDAVRPMGRTATGVRGIRL 726
Cdd:PRK05560 608 FFATKNGTVKKTSLSEFSNIRSNGIIAINLDEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIKL 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 727 GEGDSVVSLIVPRGEGA-ILTATQNGYGKRTAVEEYPTKSRATKGVISIKVTDRNGPVVGAVQVDDADQIMMITDAGTLV 805
Cdd:PRK05560 688 REGDEVVSMDVVREDSQeILTVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLI 767
|
810 820 830
....*....|....*....|....*....|....*..
gi 742382571 806 RTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEP 842
Cdd:PRK05560 768 RTRVSEISITGRNTQGVRLIRLDEGDKVVSVARVAEE 804
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-836 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1494.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 1 MSDL--AREITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYH 78
Cdd:COG0188 1 MSDPppAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 79 PHGDSAVYDTIVRMAQPFSLRYTLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDV 158
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 159 MPTKIPNLLVNGASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRG 238
Cdd:COG0188 161 LPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 239 KIYIRARAEVEvDPKNGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEIKRDAVGEVVLN 318
Cdd:COG0188 241 SIRVRAKAEIE-ELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLN 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 319 NLYSQTQLQVSFGINMVALHHGQPKIMPLKDILAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIR 398
Cdd:COG0188 320 QLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIR 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 399 RAPTPAEAKAGLIAqawdlgnvkamlegagddaarpewlepefgirdgKYWLTEQQAQAILDLRLQKLTGLEHEKLLDEY 478
Cdd:COG0188 400 ASKDPDEAKEALME----------------------------------RFGLSEIQAEAILDMRLRRLTGLEREKIEDEY 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 479 KELLTQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYE 558
Cdd:COG0188 446 AELLKEIAELEDILASEERLLKIIKEELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYR 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 559 AQRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVR 638
Cdd:COG0188 526 AQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVK 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 639 EYEEGVNVFMATASGTVKKTALTEFSRPRTAGIIAVNLNEGDELIGVDLTAGKDEVMLFSAQGKVVRFKEDAVRPMGRTA 718
Cdd:COG0188 606 EFDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTA 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 719 TGVRGIRLGEGDSVVSLIVPRGEGAILTATQNGYGKRTAVEEYPTKSRATKGVISIKVTDRNGPVVGAVQVDDADQIMMI 798
Cdd:COG0188 686 RGVRGIRLKEGDEVVGMAVVDEEDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLI 765
|
810 820 830
....*....|....*....|....*....|....*...
gi 742382571 799 TDAGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGL 836
Cdd:COG0188 766 TSSGQLIRTPVSDIRVTGRNTQGVRLIRLDEGDKVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
8-841 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1398.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 8 ITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYD 87
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 88 TIVRMAQPFSLRYTLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMPTKIPNLL 167
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 168 VNGASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKIYIRARAE 247
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 248 VEVDPKnGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEIKRDAVGEVVLNNLYSQTQLQ 327
Cdd:TIGR01063 241 IEEDSK-GREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQLQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 328 VSFGINMVALHHGQPKIMPLKDILAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEAK 407
Cdd:TIGR01063 320 VSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 408 AGLIAQawdlgnvkamlegagddaarpewlepefgirdgkYWLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLTQIAE 487
Cdd:TIGR01063 400 TRLVER----------------------------------FSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIAD 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 488 LLHILGSADRLMEVIREELELIRDQFGDERRTEITAN-SADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKG 566
Cdd:TIGR01063 446 LEDILASEERVLEIIREELEEIKEQFGDPRRTEIVYDeSEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKG 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 567 KSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREYEEGVNV 646
Cdd:TIGR01063 526 VSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYL 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 647 FMATASGTVKKTALTEFSRPRTAGIIAVNLNEGDELIGVDLTAGKDEVMLFSAQGKVVRFKEDAVRPMGRTATGVRGIRL 726
Cdd:TIGR01063 606 FFATKNGVVKKTSLTEFSNIRSNGIIAIKLDDGDELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKL 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 727 GEGDSVVSLIVPRGEGAILTATQNGYGKRTAVEEYPTKSRATKGVISIKVTDRNGPVVGAVQVDDADQIMMITDAGTLVR 806
Cdd:TIGR01063 686 KNEDFVVSLLVVSEESYLLIVTENGYGKRTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIR 765
|
810 820 830
....*....|....*....|....*....|....*
gi 742382571 807 TRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAE 841
Cdd:TIGR01063 766 TSVQDVSEQGRNTQGVRLIRLDEDDKLVSVSKVAK 800
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
1-771 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 865.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 1 MSDLAREITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH 80
Cdd:PRK05561 3 DMSMLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 81 GDSAVYDTIVRMAQPFSLRYTLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMP 160
Cdd:PRK05561 83 GDSSIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 161 TKIPNLLVNGASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPT-AAIINGRRGIEEAYRTGRGK 239
Cdd:PRK05561 163 ARFPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTgGEIITGRDGIRKAYETGRGS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 240 IYIRARAEVEvDPKNGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDG-MRIVIEIKRDAVG-EVVL 317
Cdd:PRK05561 243 IRVRARWEIE-DLAGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENpVRIVIEPKSNRVDpEALM 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 318 NNLYSQTQLQVSFGINMVALH-HGQPKIMPLKDILAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIEL 396
Cdd:PRK05561 322 NHLFATTDLESSYRVNMNAIGlDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRI 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 397 IRrapTPAEAKAGLIAqawdlgnvkamlegagddaarpewlepEFGirdgkywLTEQQAQAILDLRLQKLTGLEHEKLLD 476
Cdd:PRK05561 402 IR---ESDEPKANLMA---------------------------RFD-------LSEIQAEAILELRLRRLAKLEEIEIRK 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 477 EYKELLTQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSAD--INIEDLINQEDVVVTLSHQGYVKyqpl 554
Cdd:PRK05561 445 EQDELRKEIAELEAILASERKLRKLIKKELKADAKKFGDPRRTPIEEAEEAiaIDEEALIPDEPVTVVLSKKGWVR---- 520
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 555 tdyeaqRRGGKGKSAA--RIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEAsRGArGRPIVNLLPLEANERIT 632
Cdd:PRK05561 521 ------RAKGHSIDASglSFKEGDSLLFAFEARTTDKLLLFTSTGRVYSLPVHELPSA-RGD-GEPLTGLVDLAPGEEIV 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 633 AILPvreYEEGVNVFMATASGTVKKTALTEFSRPRTAGIIAVNLNEGDELIGVDLTAGKDEVMLFSAQGKVVRFKEDAVR 712
Cdd:PRK05561 593 HVLA---FDPDQKLLLASSAGYGFVVTLEDLVARTRAGKAVINLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSELP 669
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 742382571 713 PMGRtATGVRGIRLG-EGDSVVSLIVPRGEGAILTATQNGYGKRTAVEEYPT--KSRATKGV 771
Cdd:PRK05561 670 ELGK-GKGVKLINLPkDDDGLVDLRVLNPEDGLVLLTAGKRKLKLKPSELEKyrGKRARRGR 730
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
30-507 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 721.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 30 VGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYTLVDGQGNF 109
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 110 GSIDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGASGIAVGMATNIPPHNLTE 189
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 190 VINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKIYIRARAEVEVDPknGRETIIVHEIPYQVN 269
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDE--GRNTIEITELPYQVN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 270 KARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEIKRDAVGEVVLNNLYSQTQLQVSFGINMVALHH-GQPKIMPLK 348
Cdd:cd00187 239 KAKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDPnGRPKKLNLK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 349 DILAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAptpAEAKAGLIAQAWDLGnvkamlegag 428
Cdd:cd00187 319 EILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELEKLG---------- 385
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 742382571 429 ddaarpewlepefgirdgkywLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLTQIAELLHILGSADRLMEVIREELE 507
Cdd:cd00187 386 ---------------------FSEIQADAILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELD 443
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
11-499 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 664.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 11 VNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIV 90
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 91 RMAQPFSLRYTLVDGQGNFGSI-DGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMPTKIPNLLVN 169
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 170 GASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINgrrgieeayrtGRGKIYIRARAEVE 249
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 250 vdpknGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDES-DKDGMRIVIEIKRDAVGEVVLNNLYSQTQLQV 328
Cdd:smart00434 230 -----DDNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQT 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 329 SFGINMVALH-HGQPKIMPLKDILAAFVRHRREVVTRRTIFELRKAR-DRAHILEALAIALANIDPIIELIRRAPTPA-E 405
Cdd:smart00434 305 TFSINMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDLAkE 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 406 AKAGLIAqawdlgnvkamlegagddaarpewlepefgirdgKYWLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLTQI 485
Cdd:smart00434 385 AKEKLME----------------------------------RFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEI 430
|
490
....*....|....
gi 742382571 486 AELLHILGSADRLM 499
Cdd:smart00434 431 EDLEKILASEEWLN 444
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
8-734 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 648.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 8 ITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYD 87
Cdd:PRK13979 13 IIKIPLEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSVYD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 88 TIVRMAQPFSLRYTLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMPTKIPNLL 167
Cdd:PRK13979 93 AMVILAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 168 VNGASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKIYIRARAE 247
Cdd:PRK13979 173 VNGAFGIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTKELMNYIKGPDLPTGGILIGKKSLLSAYETGEGKVTLRAKTK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 248 VEvDPKNGRETIIVHEIPYQVNKARLIEKIAELVKEKR----VEGISALRDESDKDGMRIVIEIKRDA---VGEVVLNNL 320
Cdd:PRK13979 253 IE-KLENGRLGIVITEFPYRRNKAKLLQTISEMTADKKhskaLENISDIRDESDRNGIRAVIEFKKSAdedVAEKVLKYL 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 321 YSQTQLQVSFGINMVALHHGQPKIMPLKDILAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA 400
Cdd:PRK13979 332 YKKTDLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIKTIRSS 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 401 PTPAEAKAGLIAqawdlgnvkamlegagddaarpewlepefgirdgKYWLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE 480
Cdd:PRK13979 412 KSKKDASENLIE----------------------------------KFGFTDEQAEAILELMLYRLTGLEIVAFEKEYKE 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 481 LLTQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITA--NSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYe 558
Cdd:PRK13979 458 LEKLIKKLTKILSSEKELLKVIKKELKEVKEKYGDERRTSIIEddEKAKIDVEELIVVEDVVITLSNEGFIKRIPLKSY- 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 559 aqRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPE---ASRGARGRPIVNLLPLEaNERITAIL 635
Cdd:PRK13979 537 --NRSNSNVEDIEYREGDFNKFLIQSNTKDTLLIFTDKGNMYQIKGINIPEfkwKEKGERLDEIIKGIDLE-SEKIIEAY 613
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 636 PVREYEEGVNVFMATASGTVKKTALTEFSRPRTAgIIAVNLNEGDELIGVDLTAGKDEVMLFSAQGKV-VRF--KEDAVR 712
Cdd:PRK13979 614 SIEDFTPQKDFIFITDSGGIKKTSLDKFVTNYTK-LMALKLKKGEKLIKVKLVDRTREEKFIKIKTKKgLSFtvEEPELE 692
|
730 740
....*....|....*....|..
gi 742382571 713 PMGRTATGVRGIRLGEGDSVVS 734
Cdd:PRK13979 693 PVDRNIIGYQLFDLLPNDSIKK 714
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
13-777 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 630.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 13 IEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRM 92
Cdd:TIGR01061 6 LEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYDAMVRM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 93 AQPFSLRYTLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGAS 172
Cdd:TIGR01061 86 SQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLLINGAT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 173 GIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKIYIRARAEVEVDp 252
Cdd:TIGR01061 166 GIAAGYATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIRAKIEIEVN- 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 253 KNGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEIKRDAVGEVVLNNLYSQTQLQVSFGI 332
Cdd:TIGR01061 245 KNGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESDRNGIRIIIELKKDANAEKILNFLFKHTDLQINYNF 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 333 NMVALHHGQPKIMPLKDILAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEAKAGLIA 412
Cdd:TIGR01061 325 NMVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKENLID 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 413 qawdlgnvkamlegagddaarpewlepefgirdgKYWLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLTQIAELLHIL 492
Cdd:TIGR01061 405 ----------------------------------NFKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQII 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 493 GSADRLMEVIREELELIRDQFGDERRTEI--TANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKGKsaa 570
Cdd:TIGR01061 451 ASEKARNKLLKKQLEEYKKQFAQQRRSQIedFINQIKINESELIENEDYYVLITKAGYIKRTSNRSFASSKYTDFGS--- 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 571 riKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREYE-EGVNVFMA 649
Cdd:TIGR01061 528 --KDDDILFAQTIANTTDQILIFTSLGNIINIPVHKLADIRWKDLGEHLSNKITFDENETIVFVGTMNEFDvDQPILVLA 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 650 TASGTVKKTALTEFS-RPRTAGIIAVNLNEGDELIGVDLTAGKDEVMLFSAQGKVVRFKEDAVRPMGRTATGVRGIRLGE 728
Cdd:TIGR01061 606 SKLGMVKRIELTELNiKRNSKATLCIKLKDKDHLISAFLQQKDKLICLVSDLGYALVFHTNEIPVVGAKAAGVKGMKLKE 685
|
730 740 750 760
....*....|....*....|....*....|....*....|....*....
gi 742382571 729 GDSVVSLIVPRGEGAILTATQNGYGKRTAVEEYPTKSRATKGVISIKVT 777
Cdd:TIGR01061 686 DDQVKSGVIFEANESLVLLTQRGSVKRLSISELVVTSRAATGKKLLPLK 734
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
32-507 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 628.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 32 RALPDVRDGLKPVHRRVLYAMNVLGNDwNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYTLVDGQGNFGS 111
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFELLNL-DKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 112 -IDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGASGIAVGMATNIPPHNLTEV 190
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 191 INGCLAYIDDEDISIegLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKIYIRARAEVEVdpkngRETIIVHEIPYQVNK 270
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED-----RKTIVITELPYGVWT 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 271 ARLIEKIAELVKEKRVEGISALRDESDKdGMRIVIEIKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMPLKDI 350
Cdd:pfam00521 233 SDLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 351 LAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEAKAGLIAQawdlgnvkamlegagdd 430
Cdd:pfam00521 312 LKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE----------------- 374
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 742382571 431 aarpewlepefgirdgkywLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLTQIAELLHILGSADRLMEVIREELE 507
Cdd:pfam00521 375 -------------------LSEIQADYLLDMRLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
8-726 |
2.40e-165 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 499.05 E-value: 2.40e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 8 ITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYD 87
Cdd:TIGR01062 1 IENIDLGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 88 TIVRMAQPFSLRYTLVDGQGNFGSIDG-DSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNYDGTEKIPDVMPTKIPNL 166
Cdd:TIGR01062 81 AMVLMAQPFSYRYPLVDGQGNWGAPDDpKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 167 LVNGASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAA-IINGRRGIEEAYRTGRGKIYIRAR 245
Cdd:TIGR01062 161 LLNGTTGIAVGMATDIPPHNLHELADAALYLIDNPKAGLDDILNIVQGPDFPTEAeIIDKAEEIRKIYETGRGSFRMRAR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 246 AEVEvdpkngRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESD-KDGMRIVIEIKRDAVG-EVVLNNLYSQ 323
Cdd:TIGR01062 241 WKKE------DGQIVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDhENPIRVVIVPRSNRVDpDIVMEHLFAT 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 324 TQLQVSFGINM--VALHHgQPKIMPLKDILAAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRap 401
Cdd:TIGR01062 315 TDLEKSYRLNMnmIGLDN-VPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIRE-- 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 402 tpaeakagliaqawdlgnvkamlegagDDAARPEWLEpefgirdgKYWLTEQQAQAILDLRLQKLTGLEHEKLLDEYKEL 481
Cdd:TIGR01062 392 ---------------------------EDEPKTILME--------RFKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSEL 436
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 482 LTQIAELLHILGSADRLMEVIREELELIRDQFGDERRT-----EITANSADInieDLINQEDVVVTLSHQGYVKYQPLTD 556
Cdd:TIGR01062 437 EKERAILEKILKSERELNQLVKKEIQADATKYGLARRSsleerEEAKQVSEI---DMIPKEPVTIILSKMGWVRSAKGHD 513
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 557 YEAqrrggkgkSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEAsRGaRGRPIVNLLPLEANERITAILP 636
Cdd:TIGR01062 514 IDL--------STLKYKAGDSEKAIIEGKSNQKVVFIDSTGRSYALDPDNLPSA-RG-QGEPLTGKLLLPIGATITNILM 583
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 637 VREYEEgvnVFMATASGTVKKTALTEFSRPRTAGIIAVNLNEGDELIG-VDLTAGKDEVMLFSAQGKVVRFKEDAVrPMG 715
Cdd:TIGR01062 584 YSPNQL---LLMASDAGYGFLCNFNDLIARNKAGKALINLPENASVIApLPVNGDSDMIAAITEAGRMLVFPIDDL-PEL 659
|
730
....*....|.
gi 742382571 716 RTATGVRGIRL 726
Cdd:TIGR01062 660 SKGKGNKLIRI 670
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
10-383 |
2.16e-68 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 239.61 E-value: 2.16e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 10 PVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLgNDWNkaYKKSARVVGDVIgKYHPHGDSAVYDTI 89
Cdd:PRK09631 1 MMDIKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSLFEM-HDGK--FHKVANVVGNTM-KYHPHGDASIYEAL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 90 VRMAQpfslRYTLVDGQGNFGSI-DGDSAAAMRYTEIRLAKIAHELMadLDKETVDFVDNYDGTEKIPDVMPTKIPNLLV 168
Cdd:PRK09631 77 VNLAN----KDLFIDKQGNFGNLfTGDPASAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPVILI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 169 NGASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEglmehipgPDFPTAAIINgrrgiEEAYRTGRGKIYIRARAEv 248
Cdd:PRK09631 151 QGAEGIAVGMATKILPHNFNEILQAVKSELLGESFALY--------PDFPTGGIVD-----VSEYADGNGKVLVRAKIE- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 249 EVDPKngreTIIVHEIPYQVNKARLIEKIAELVKEKRVEgISALrdeSDKDGMRIVIEIK--RDAVGEVVLNNLYSQTQL 326
Cdd:PRK09631 217 TKDEK----TIVIREIPFGTTTESLIASIEKAARKGKIK-ISSI---NDYTAENVEIEIKlpRGVYASEVIEALYAYTDC 288
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 742382571 327 QVSFGINMVALHHGQPKIMPLKDILAAFVRHRREVVTRRtiFELrkarDRAHILEAL 383
Cdd:PRK09631 289 EVSISVNLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKME--LEL----ERAKLLEKI 339
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
18-521 |
1.04e-54 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 204.47 E-value: 1.04e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 18 KNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDwnkAYKKSARVVGDVIgKYHPHGDSAVYDTIVRMAQpfs 97
Cdd:PRK12758 28 KNWFLDYASYVILERAVPHIEDGLKPVQRRILHSMKEMDDG---RYNKVANVVGHTM-QYHPHGDASIGDALVQLGQ--- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 98 lRYTLVDGQGNFGSI-DGDSAAAMRYTEIRLAKIAHELMadLDKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGASGIAV 176
Cdd:PRK12758 101 -KDLLIDTQGNWGNIlTGDGAAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIAV 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 177 GMATNIPPHNLTEVINGCLAYIDDEDISIEglmehipgPDFPTAAIIN------GRRGieeayrtgrGKIYIRARAEvEV 250
Cdd:PRK12758 178 GLSTKILPHNFNELIDASIAYLKGKEFKLY--------PDFPTGGIIDvsnyndGERG---------GRVRVRAKIE-KL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 251 DPKngreTIIVHEIPYQVNKARLIEKIAEL-----VKEKRVEGISAlrdesdkDGMRIVIEIKRDAVGEVVLNNLYSQTQ 325
Cdd:PRK12758 240 DKK----TLVITEIPYGTTTSSLIDSILKAndkgkIKIKKVEDNTA-------ADVEILVHLAPGVSPDKTIDALYAFTD 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 326 LQVSFGINMVALHHGQPKIMPLKDILAAFVRHRREVVTRRTIFELRKARDRAHI--LEALAI---------ALANIDPII 394
Cdd:PRK12758 309 CEVSISPNACVIIDNKPHFLGVSDILRRSTDHTVSLLKQELEIRLSELEEQWHFasLEKIFIeeriykeieEAETWEAVI 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 395 ELIRRAPTPaeAKAGLIAQAWDlgnvkamlegagDDAARpewlepefgirdgkywLTEQQAQAILDLRLQKltgleHEKL 474
Cdd:PRK12758 389 EAIDKGLEP--FKKQFIREVTE------------DDIVR----------------LTEIKIKRISKFDSDK-----ADEL 433
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 742382571 475 LDEYKElltQIAELLHILgsaDRLMEVIREELELIRDQFGD--ERRTEI 521
Cdd:PRK12758 434 IARLEA---EIAEVKHHL---AHLTDYAIAYFTNLKKKYGKgrERKTEI 476
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
12-351 |
9.83e-48 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 177.39 E-value: 9.83e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 12 NIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLgnDWNKAYKksarvVGDVIGK---YHPHGDSAVYDT 88
Cdd:PRK09630 3 DVSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTLFRM--DDGKMHK-----VANIAGRtmaLHPHGDAPIVEA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 89 IVRMAQpfslRYTLVDGQGNFGS-IDGDSAAAMRYTEIRLAKIAHELMADLDkeTVDFVDNYDGTEKIPDVMPTKIPNLL 167
Cdd:PRK09630 76 LVVLAN----KGYLIDTQGNFGNpLTGDPHAAARYIEARLSPLAKEVLFNTD--LMTFHDSYDGREKEPDILPAKLPLLL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 168 VNGASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEglmehipgPDFPTAAIINGrrgieEAYRTGRGKIYIRARAE 247
Cdd:PRK09630 150 LHGVDGIAVGMTTKIFPHNFCELLEAQIAILNDQPFTLL--------PDFPSGGTMDA-----SEYQDGLGSITLRASID 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 248 VeVDPKngreTIIVHEIPYQVNKARLIEKIAELVKEKRVEgISALRDESdKDGMRIVIEIKRDAVGEVVLNNLYSQTQLQ 327
Cdd:PRK09630 217 I-INDK----TLLIKEICPSTTTETLIRSIENAAKRGIIK-IDSIQDFS-TDLPHIEIKLPKGIYAKDLLRPLFTHTECQ 289
|
330 340
....*....|....*....|....
gi 742382571 328 VSFGINMVALHHGQPKIMPLKDIL 351
Cdd:PRK09630 290 VILTSRPTAIYQNKPVETSISEIL 313
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
12-397 |
9.00e-43 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 161.76 E-value: 9.00e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 12 NIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDV--IGkYHpHGDSAVYDTI 89
Cdd:PHA02592 7 SLKSIVNNEALEYAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGVadLG-YH-HGETSAQDAG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 90 VRMAQPFSLRYTLVDGQGNFGSIDGDSAAAMRYTEIRLakiaHELMADLDKETvDFVDNYDGTEKIPDV--MPTkIPNLL 167
Cdd:PHA02592 85 ALMANTWNNNIPLLDGQGNFGSRLVQKAAAARYIFARV----HDNFRKIYKDE-DLAPVHEDPEHIPPAfyLPI-IPMVL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 168 VNGASGIAVGMATNIPPHNLTEVINGCLAYIDDEDISieglmehIPGPDFPtaaiinGRRGieEAYRTGRGKIYIRARAE 247
Cdd:PHA02592 159 LNGVSGIATGYATNILPHSPKSVIKAVLAALNGKDIT-------EPKVQFP------EFKG--EVVEIEPGSYEIRGTYE 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 248 VevdpkNGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGIsalrDESDKDGMRIVIEIKRDAVGEVVLNNLYSQTQLQ 327
Cdd:PHA02592 224 L-----NGKTKLHITEIPVKYDRETYVAVLDPLEEKGKIVSY----DDCTEDGFRFKVTLKREENEEATHEKIMKDFGLI 294
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 742382571 328 VSFGINMVALH-HGQPKIMP-LKDILAAFVRHRREVVTRRTIFELRKARdrahilEALAIALANIDPIIELI 397
Cdd:PHA02592 295 ERVSQNITVINeNGKLKVYEnAEDLIRDFVEIRKTYVQKRIQYEIKETE------EAFDLALAKAEFIKRVI 360
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
32-382 |
4.18e-25 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 112.49 E-value: 4.18e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 32 RALPDVRDGLKPVHRRVLYAmnVLGNDWnKAYKKSARVVGDVI--GKYHpHGDSAVYDTIVRMAQPF--SLRYTLVDGQG 107
Cdd:PLN03128 673 RSIPSMVDGLKPSQRKVLFA--CFKRNL-KSEIKVAQLSGYVAehSAYH-HGEASLASTIIGMAQDFvgSNNINLLTPSG 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 108 NFGS--IDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNyDGTEKIPD-VMPTkIPNLLVNGASGIAVGMATNIPP 184
Cdd:PLN03128 749 QFGTrlQGGKDAASARYIFTRLSPITRALFPKDDDVLLNYLNE-DGQSIEPEwYCPI-IPMVLVNGSEGIGTGWSTFIPN 826
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 185 HNLTEVINGCLAYIDDEDisieglmehiPGPDFPTAAIINGRrgIEEAYRTGRGKIYIRARAEvevdpKNGRETIIVHEI 264
Cdd:PLN03128 827 YNPRDIIANIRRLLRGEE----------LEPMHPWYRGFKGT--ITEVSTSRSGSYTVTGIIE-----QIGDTTIRITEL 889
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 265 PYQV---NKARLIEKIAELVKEKRVEgISALRDESDKDGMRIVIEIKRDAVGEVVLNNLYSQTQLQVSFGI-NMVAL--- 337
Cdd:PLN03128 890 PVRKwtqDYKEFLEALLTGTKKKEPE-IKDFKENHTDTTVHFTVTLSEEKMARALAEGLEKKFKLSTTISTsNMHLFdkd 968
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 742382571 338 ----HHGQPkimplKDILAAFVRHR-------REVVTRRTIFELRKARDRAHILEA 382
Cdd:PLN03128 969 gkikKYDSP-----EDILEEFFHLRldlyvkrKEVLLENLEYELKKLDNKARFILA 1019
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
32-523 |
7.39e-25 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 111.68 E-value: 7.39e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 32 RALPDVRDGLKPVHRRVLYAMnvlgndWNKAYKKSARVVgDVIG------KYHpHGDSAVYDTIVRMAQPF----SLRYT 101
Cdd:PTZ00108 680 RSIPSLVDGLKPGQRKILFAC------FKRNLKNEIKVA-QLSGyvsehsAYH-HGEQSLQQTIVGMAQNFvgsnNINLL 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 102 LVDGQgnFGS--IDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNyDGTEKIPD-VMPTkIPNLLVNGASGIAVGM 178
Cdd:PTZ00108 752 YPCGQ--FGSrlQGGKDHAAARYIFTKLSKITRYIFPEEDDPILDYLED-DGQSVEPFyYVPI-IPMVLVNGAEGIGTGF 827
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 179 ATNIPPHNLTEVINGCLAYIDDEDisiegLMEHIPgpdfptaaIINGRRGIEEayRTGRGKIYIRARAEvevdpKNGRET 258
Cdd:PTZ00108 828 STSIPNYNPLDIIDNLRRRLNGEE-----VRPLVP--------WYRGFKGTIE--RNPKGKFISKGIYE-----KVPDGT 887
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 259 IIVHEIPYQVNKARLIEKIAELVKEKRvEGISALRDESDKDGMRIVIEIKRDAVGEVVLNNLYSQTQLQVSFGI-NMVAL 337
Cdd:PTZ00108 888 VEITELPIGKWTEDYKEFLESETLKEK-DVIVDYRDYSTANTVHFTVKLNDGVLEQWEEEGIEKVFKLKSTISTtNMVLF 966
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 338 HHGQ--PKIMPLKDILAAFVRHRREVVTRRTIFELRKARDRAHILEA-----LAIALANIDpiielIRRAPtpaeaKAGL 410
Cdd:PTZ00108 967 DENGkiKKYSDALDILKEFYLVRLDLYKKRKEYLLGKLERELARLSNkvrfiKHVINGELV-----ITNAK-----KKDL 1036
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 411 IAQAWDLGNV----KAMLEGAGDDAARPEWLEPEFGIRDGKYWLTEQQAQA---ILDLRLQKLTgLEH-EKLLDEYKELL 482
Cdd:PTZ00108 1037 VKELKKLGYVrfkdIIKKKSEKITAEEEEGAEEDDEADDEDDEEELGAAVSydyLLSMPIWSLT-KEKvEKLNAELEKKE 1115
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 742382571 483 TQIAELLHIlgsadrlmEVI---REELELIRDQFGDERRTEITA 523
Cdd:PTZ00108 1116 KELEKLKNT--------TPKdmwLEDLDKFEEALEEQEEVEEKE 1151
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
32-201 |
4.02e-15 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 80.29 E-value: 4.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 32 RALPDVRDGLKPVHRRVLYAmnvlgnDWNKAYKKSARV---VGDV--IGKYHpHGDSAVYDTIVRMAQPF--SLRYTLVD 104
Cdd:PLN03237 698 RSIPSMVDGLKPGQRKILFC------SFKRNFVKEAKVaqlSGYVseHSAYH-HGEQSLASTIIGMAQDFvgSNNINLLL 770
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742382571 105 GQGNFG--SIDGDSAAAMRYTEIRLAKIAHELMADLDKETVDFVDNyDGTEKIPD-VMPTkIPNLLVNGASGIAVGMATN 181
Cdd:PLN03237 771 PNGQFGtrLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDYLNE-DGQSIEPTwYMPI-IPTVLVNGAEGIGTGWSTF 848
|
170 180
....*....|....*....|
gi 742382571 182 IPPHNLTEVINGCLAYIDDE 201
Cdd:PLN03237 849 IPNYNPRDIVANIRRLLNGE 868
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
692-737 |
6.36e-13 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 63.66 E-value: 6.36e-13
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 742382571 692 DEVMLFSAQGKVVRFKEDAVRPMGRTATGVRGIRLGEGDSVVSLIV 737
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLV 46
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
793-839 |
5.70e-11 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 58.27 E-value: 5.70e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 742382571 793 DQIMMITDAGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRV 839
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
744-790 |
9.59e-09 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 51.72 E-value: 9.59e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 742382571 744 ILTATQNGYGKRTAVEEYPTKSRATKGVISIKVTDrNGPVVGAVQVD 790
Cdd:pfam03989 3 LLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKE-GDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
538-585 |
1.01e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 51.72 E-value: 1.01e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 742382571 538 DVVVTLSHQGYVKYQPLTDYEAQRRGGKGKSAARIKEEDFIDRLLVAN 585
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
588-638 |
1.06e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 51.72 E-value: 1.06e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 742382571 588 DTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNllpLEANERITAILPVR 638
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGIN---LKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
645-688 |
7.25e-06 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 43.63 E-value: 7.25e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 742382571 645 NVFMATASGTVKKTALTEFSRPR--TAGIIAVNLNEGDELIGVDLT 688
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGrgAKGVKGINLKEGDKVVSVLVV 47
|
|
| |
