|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
1-367 |
0e+00 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 628.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 1 MSDELSGKSGKVRVMYVRSEDGDEKNGKQKRTPD-KRRGDGDNRGRKGR--DSAPRGGRDRDNKdgaerggkwrsesagr 77
Cdd:PRK10864 1 MNDELKGKSGKVKVMYVRSDDDSDKRTHNPRTGKgGGRPSGKSRADGGRrpARDDRNSQSRDRK---------------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 78 erprpprrepvdHADSPWKTVSRAPGEE----PDHGGISGKSQIDPEQIRRQRSEETRVYGENACQALFLSRPEAIVRGW 153
Cdd:PRK10864 65 ------------WEDSPWRTVSRAPGDEtpekADHGGISGKSFIDPEVLRRQRAEETRVYGENACQALFQSRPEAIVRAW 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 154 FLQEVTPRFREALRWMAANRKAYHVVEDDELIRASGTEHHGGVCFLIKKRRGLDVTAYLREAGDTDCVLALEDVGNPHNL 233
Cdd:PRK10864 133 FIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTEHHGGVCFLIKKRNGTDVQQWLAQAGAQDCVLALEDVGNPHNL 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 234 GGIMRSCAHFGVKGVLVRDASQLESGAAVRTAEGGAEHVKAISADGLVDALAQFRAAGYTIVTTSSHKGTTLSKVSLPAK 313
Cdd:PRK10864 213 GGIMRSCAHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGDSFVDVLDDFRQAGYTIVTTSSHKGTPLFKASLPAK 292
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 742463198 314 TVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEWWRQNHG 367
Cdd:PRK10864 293 MVLVLGQEYDGLSDAARQQGDLSVSIDGTGNVESLNVSVATGVLLAEWWRQNKA 346
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
123-367 |
1.10e-70 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 221.99 E-value: 1.10e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 123 RRQRSEETR--VYGENACQALfLSRPEAIVRGWFLQEVTPRFREALRWMAANRKAYHVVEDDELIRASGTEHHGGVCFLI 200
Cdd:COG0566 18 KKYREEEGLflAEGRHAVEEA-LKAGREIEELLVTEGALDRLAELLALAKAAGIPVYEVSREVLDKLSGTETHQGVLAVV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 201 KKRRGLDVTAYLREAGDTDCVLALEDVGNPHNLGGIMRSCAHFGVKGVLV-RDASQLESGAAVRTAEGGAEHVKAISADG 279
Cdd:COG0566 97 RPPEYADLEDLLAEAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILpKRRADPYNPKVVRASAGALFHVPVARVTN 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 280 LVDALAQFRAAGYTIVTTSSHKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLA 359
Cdd:COG0566 177 LADALEELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAILLY 256
|
....*...
gi 742463198 360 EWWRQNHG 367
Cdd:COG0566 257 EAARQRRA 264
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
220-361 |
4.36e-51 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 167.22 E-value: 4.36e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 220 CVLALEDVGNPHNLGGIMRSCAHFGVKGV-LVRDASQLESGAAVRTAEGGAEHVKAISADGLVDALAQFRAAGYTIVTTS 298
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGViLSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 742463198 299 SHKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEW 361
Cdd:cd18095 81 LDGGSSLYDLDLPKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
221-358 |
1.07e-40 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 139.97 E-value: 1.07e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 221 VLALEDVGNPHNLGGIMRSCAHFGVKGVLV--RDASQLESGAAVRTAEGGAEHVKAISADGLVDALAQFRAAGYTIVTTS 298
Cdd:pfam00588 3 VVVLDNIQDPGNLGAIIRTAAAFGADGLILvePRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVATS 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 299 sHKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILL 358
Cdd:pfam00588 83 -LGGKSLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIAL 141
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
214-364 |
2.77e-29 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 113.21 E-value: 2.77e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 214 EAGDTDCVLALEDVGNPHNLGGIMRSCAHFGVKGVLV--RDASQLESGAaVRTAEGGAEHVKAISADGLVDALAQFRAAG 291
Cdd:TIGR00186 85 KSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILpkRRSAPLNSTV-VKTSSGAVEYVPLARVTNLSRTITKLKESG 163
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 742463198 292 YTIVTTSSHKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEWWRQ 364
Cdd:TIGR00186 164 FWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQ 236
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
132-202 |
4.09e-07 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 46.76 E-value: 4.09e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 742463198 132 VYGENACQALfLSRPEAIVRGWFLQEVTPRFREALRWMAANRKAYHVVEDDELIRASGTEHHGGVCFLIKK 202
Cdd:smart00967 1 IEGRHAVEEA-LKSGRRIKELYLTEGRAERLKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
1-367 |
0e+00 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 628.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 1 MSDELSGKSGKVRVMYVRSEDGDEKNGKQKRTPD-KRRGDGDNRGRKGR--DSAPRGGRDRDNKdgaerggkwrsesagr 77
Cdd:PRK10864 1 MNDELKGKSGKVKVMYVRSDDDSDKRTHNPRTGKgGGRPSGKSRADGGRrpARDDRNSQSRDRK---------------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 78 erprpprrepvdHADSPWKTVSRAPGEE----PDHGGISGKSQIDPEQIRRQRSEETRVYGENACQALFLSRPEAIVRGW 153
Cdd:PRK10864 65 ------------WEDSPWRTVSRAPGDEtpekADHGGISGKSFIDPEVLRRQRAEETRVYGENACQALFQSRPEAIVRAW 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 154 FLQEVTPRFREALRWMAANRKAYHVVEDDELIRASGTEHHGGVCFLIKKRRGLDVTAYLREAGDTDCVLALEDVGNPHNL 233
Cdd:PRK10864 133 FIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTEHHGGVCFLIKKRNGTDVQQWLAQAGAQDCVLALEDVGNPHNL 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 234 GGIMRSCAHFGVKGVLVRDASQLESGAAVRTAEGGAEHVKAISADGLVDALAQFRAAGYTIVTTSSHKGTTLSKVSLPAK 313
Cdd:PRK10864 213 GGIMRSCAHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGDSFVDVLDDFRQAGYTIVTTSSHKGTPLFKASLPAK 292
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 742463198 314 TVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEWWRQNHG 367
Cdd:PRK10864 293 MVLVLGQEYDGLSDAARQQGDLSVSIDGTGNVESLNVSVATGVLLAEWWRQNKA 346
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
123-367 |
1.10e-70 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 221.99 E-value: 1.10e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 123 RRQRSEETR--VYGENACQALfLSRPEAIVRGWFLQEVTPRFREALRWMAANRKAYHVVEDDELIRASGTEHHGGVCFLI 200
Cdd:COG0566 18 KKYREEEGLflAEGRHAVEEA-LKAGREIEELLVTEGALDRLAELLALAKAAGIPVYEVSREVLDKLSGTETHQGVLAVV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 201 KKRRGLDVTAYLREAGDTDCVLALEDVGNPHNLGGIMRSCAHFGVKGVLV-RDASQLESGAAVRTAEGGAEHVKAISADG 279
Cdd:COG0566 97 RPPEYADLEDLLAEAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILpKRRADPYNPKVVRASAGALFHVPVARVTN 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 280 LVDALAQFRAAGYTIVTTSSHKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLA 359
Cdd:COG0566 177 LADALEELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAILLY 256
|
....*...
gi 742463198 360 EWWRQNHG 367
Cdd:COG0566 257 EAARQRRA 264
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
220-361 |
4.36e-51 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 167.22 E-value: 4.36e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 220 CVLALEDVGNPHNLGGIMRSCAHFGVKGV-LVRDASQLESGAAVRTAEGGAEHVKAISADGLVDALAQFRAAGYTIVTTS 298
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGViLSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 742463198 299 SHKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEW 361
Cdd:cd18095 81 LDGGSSLYDLDLPKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
221-358 |
1.07e-40 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 139.97 E-value: 1.07e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 221 VLALEDVGNPHNLGGIMRSCAHFGVKGVLV--RDASQLESGAAVRTAEGGAEHVKAISADGLVDALAQFRAAGYTIVTTS 298
Cdd:pfam00588 3 VVVLDNIQDPGNLGAIIRTAAAFGADGLILvePRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVATS 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 299 sHKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILL 358
Cdd:pfam00588 83 -LGGKSLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIAL 141
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
221-361 |
7.16e-38 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 132.89 E-value: 7.16e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 221 VLALEDVGNPHNLGGIMRSCAHFGVKGVLV-RDASQLESGAAVRTAEGGAEHVKAISADGLVDALAQFRAAGYTIVTTSS 299
Cdd:cd18103 2 LLILDGITDPHNLGAIIRSAEAFGVDGVIIpKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGADG 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 742463198 300 HKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEW 361
Cdd:cd18103 82 EAEKSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
221-361 |
3.29e-30 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 112.70 E-value: 3.29e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 221 VLALEDVGNPHNLGGIMRSCAHFGVKGV-LVRDASQLESGAAVRTAEGGAEHVKAISADGLVDALAQFRAAGYTIV-TTS 298
Cdd:cd18082 1 HLVLDNIRSPGNIGSIFRTADAFGVEKIyLVGPTADIFDPKAKRTSRGTHFSVPYERVDNFEEYLKSLKEEGYPLIgLEL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 742463198 299 SHKGTTLS--KVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEW 361
Cdd:cd18082 81 TDGSIPLSefKFKKPKKIALIFGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSVATGIALYEF 145
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
214-364 |
2.77e-29 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 113.21 E-value: 2.77e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 214 EAGDTDCVLALEDVGNPHNLGGIMRSCAHFGVKGVLV--RDASQLESGAaVRTAEGGAEHVKAISADGLVDALAQFRAAG 291
Cdd:TIGR00186 85 KSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILpkRRSAPLNSTV-VKTSSGAVEYVPLARVTNLSRTITKLKESG 163
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 742463198 292 YTIVTTSSHKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEWWRQ 364
Cdd:TIGR00186 164 FWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQ 236
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
221-360 |
3.77e-27 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 105.24 E-value: 3.77e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 221 VLALEDVGNPHNLGGIMRSCAHFGVKGV-LVRDASQLESGAavRTAEGGAEHVKAISADGLVDALAQFRAAGYTIVTTSS 299
Cdd:cd18092 18 TVVLENVHDPHNASAVLRTCDAFGVQDVhVIEPKNKFKKNR--GVAMGADKWLDVHRHDSTEECLAALKEQGYRIVATSL 95
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 742463198 300 HKGTT-LSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAE 360
Cdd:cd18092 96 SPDAVpLDELDYTRPTALVFGNEKDGVSEEALAAADERVYIPMYGFVESLNVSVAAAIILYE 157
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
221-358 |
3.11e-26 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 102.60 E-value: 3.11e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 221 VLALEDVGNPHNLGGIMRSCAHFGVKGVLV--RDASQLeSGAAVRTAEGGAEHVKAISADGLVDALAQFRAAGYTIVTTS 298
Cdd:cd18105 2 WLLLDEITDPQNLGAILRSAYFLGVDGVVVssKNSAPL-SPVVSKASAGALELMPIYSVDNLASFLKSSKENGWKVVGTS 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 742463198 299 SHKGTTLSKVSLPA----------KTVIVLGQEGDGLSDNAWQQGDVKVSIDG-----TGNVESLNISVATGILL 358
Cdd:cd18105 81 APPSASSDKKTIPAnelselllekPTILVLGNEGRGLRTNIKNLCDYLVSIPGgrsaeNPGVDSLNVSVAAGILL 155
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
221-361 |
2.00e-23 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 94.53 E-value: 2.00e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 221 VLALEDVGNPHNLGGIMRSCAHFGVKGVLV-RDASQLESGAAVRTAEGGAEHVKAISADgLVDALAQFRAAgYTIVTTSS 299
Cdd:cd18109 2 TLALDGIQDPGNLGTIIRTADWFGIRQIICsPDTVDPYNPKVVQASMGSIFRVQIHYTD-LPALLAELKKA-FPVYGADL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 742463198 300 HkGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGN-VESLNISVATGILLAEW 361
Cdd:cd18109 80 D-GENLYEFTLPEKGILVMGNEGHGISPEVLKLLTHRLTIPRYGKgAESLNVAVATAILLSEF 141
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
132-364 |
1.02e-22 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 95.42 E-value: 1.02e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 132 VYGENACQALFLSRPEAIVRGWFLQ-----EVTPRFREALRW----MAANRKAYhvveDDeliRASGtEHHGGVCFLIKK 202
Cdd:PRK11181 5 IYGIHAVQALLERAPERFIEVFVLKgredkRLLPLINELEAQgiviQLANRQTL----DE---KAEG-AVHQGIIARVKP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 203 RRGL---DVTAYLrEAGDTDCVLALEDVGNPHNLGGIMRSCAHFGVKGVLV-RDASQLESGAAVRTAEGGAEHVKAISAD 278
Cdd:PRK11181 77 GRQLqenDLPDLL-ASLEQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVpKDRSAQLNATAKKVACGAAETVPLIRVT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 279 GLVDALAQFRAAGYTIVTTSSHKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILL 358
Cdd:PRK11181 156 NLARTMRMLQEKNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICL 235
|
....*.
gi 742463198 359 AEWWRQ 364
Cdd:PRK11181 236 FEAVRQ 241
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
229-361 |
2.68e-22 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 91.44 E-value: 2.68e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 229 NPHNLGGIMRSCAHFGVKGVLVRDASQLESGAAVRTAEGGAEHV--KAISADGLVDALAQFRAAGYTIV----TTSShkg 302
Cdd:cd18091 10 KPPNLGGLCRTCEIFGVSKLVLPNLAVVEDKQFKALSVSAEKWLpiEEVKPEDLLPYLKEKKQEGYTIVgleqTANS--- 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 742463198 303 TTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEW 361
Cdd:cd18091 87 VSLHDFQFPKKTVLVLGNEKEGIPAELLSLLDVCVEIPQLGVIRSLNVHVSGAIAIYEY 145
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
221-365 |
1.55e-21 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 89.56 E-value: 1.55e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 221 VLALEDVGNPHNLGGIMRSCAHFGVKGVLVRDA-SQLESGAAVRTAEGGAEHVKAISADGLvDALAQFRAAGYTIVTTSS 299
Cdd:cd18104 2 ILVLEGLEKPGNLGAILRSADAAGADAVILCDPkTDLFNPNVIRASLGAVFTLPVAEASSE-ETLAWLKENKIRILATTP 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 742463198 300 HKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEWWRQN 365
Cdd:cd18104 81 KAEKLYYEADLRGPIAIVVGSESEGLSEFWLKAADERVRIPMAGQADSLNVSVAAAILLYEALRQR 146
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
220-361 |
5.59e-21 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 87.66 E-value: 5.59e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 220 CVLALEDVGNPHNLGGIMRSCAHFGVKGVLVRDASQLesgaAVRTAEGGAEHVKAISADGLVDALAQFRAAGYTIVTTSS 299
Cdd:cd18096 1 LYLVLHNVAKRHNIGTIVRSANAFGVKEVHLVGRRKF----NPFGAMGTDRHVKFRHFDTLAEAKEYLKERGIRLVGVEI 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 742463198 300 HKGTT-LSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGN-VESLNISVATGILLAEW 361
Cdd:cd18096 77 VPGAEpIETHPFPGDTAFVLGNEGTGLSDEQLAICDGFVYIPQYGSgTASLNVSVAASIVLHHF 140
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
220-361 |
1.34e-16 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 75.68 E-value: 1.34e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 220 CVLALEDVGNPHNLGGIMRSCAHFGVKGV-LVRDASQLESGAAVRTAEGGAEHVKAISADGLVDALAQFRAAGYTIV--- 295
Cdd:cd18097 1 LVVVLDNLRSAHNVGSIFRTADAAGVEKIyLCGYTPTPPHPKVAKTALGAEESVPWEHFEDTLEAVRALKARGYTIIale 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 742463198 296 TTSSHKgtTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEW 361
Cdd:cd18097 81 TTENSV--PLHEARLPRPLALVLGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAVAAAVALYEL 144
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
218-364 |
6.53e-16 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 76.18 E-value: 6.53e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 218 TDCVLALEDVGNPHNLGGIMRSCAHFGVKGVlvrDASQLESGAAVR--TAEGGAEHVKAISADGLVDALAQFRAAGYTIV 295
Cdd:PRK11081 18 PDLTVCMEQVHKPHNVSAIIRTADAVGVHEV---HAVWPGSRMRTMgsTAAGSNSWVQVKTHRTIGDAVAHLKGQGMQIL 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 296 TTS-SHKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEWWRQ 364
Cdd:PRK11081 95 ATHlSDTAVDFREIDYTRPTCILMGQEKTGISQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
221-360 |
8.52e-15 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 70.88 E-value: 8.52e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 221 VLALEDVGNPHNLGGIMRSCAHFGVKGVLVR-DASQLESGAAVRTAEGGAEHVKAI---SADGLVDALAQFRAAG--YTI 294
Cdd:cd18107 2 VVLFDRPTSPGNLGTIIRSADALGAHGLVVTgHAADVYDPKTIRASTGSLFSLPIVrvpSNRELEDWVEARKARGtpLQL 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 742463198 295 VTTSSHKGTTLSKVSLPAKTVIVLGQEGDGLSdNAWQQ-GDVKVSIDGTGNVESLNISVATGILLAE 360
Cdd:cd18107 82 VGTDEHGDHQIADHDFTRPTLLLIGNETAGLS-AAWRElCDETVSIPMAGSASSLNAACAASIFLYE 147
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
230-365 |
2.87e-10 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 57.85 E-value: 2.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 230 PHNLGGIMRSCAHFGVKGVLVRDASQLESGAAVRTAegGA---EHVKAISADGLVDALAQFRAAgyTIVTTSSHKGTTLS 306
Cdd:cd18094 10 PQNTGNIARTCAATGARLHLIEPLGFSLDDKRLKRA--GLdywDHVDLTVHDSWEAFLEALPPG--RLFLFTTKGTKPYT 85
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 742463198 307 KVSLPAKTVIVLGQEGDGLSD---NAWQqgDVKVSIDGTGNVESLNISVATGILLAEWWRQN 365
Cdd:cd18094 86 DFDFKPGDYLVFGRESTGLPEeilDAFP--DRRLRIPMRPKVRSLNLSNSVAIVLYEALRQL 145
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
230-361 |
9.74e-10 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 56.74 E-value: 9.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 230 PHNLGGIMRSCAHFGVKG-VLVRDASQLESGAAVRTAeGGAEHV--KAISADGLVDALAQFRAAgytiVTTSSHKGT--- 303
Cdd:cd18093 11 PGNIGAVARAMKNFGLSDlRLVNPRCDDPEEAARALA-SGAEDVleNAKVYDTLEEALADCDLV----VATTARPRGlrr 85
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 742463198 304 ----------TLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEW 361
Cdd:cd18093 86 plltprelaeLLKEHAAGGKVALVFGREDSGLTNEELALCDLLVTIPTNPEYPSLNLAQAVAIVLYEL 153
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
221-360 |
4.00e-09 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 54.79 E-value: 4.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 221 VLALEDVGNPHNLGGIMRSCAHFGVKGVLVRDaSQLESGA---AVRTAEGGAEHVKAISADGlVDALAQFRAAGYTIVTT 297
Cdd:cd18108 2 VVVLDGVRIVGNIGAIVRTSLALGAAGIVLVD-SDLATVAdrrLLRASRGYVFSLPVVLADR-EEAVAFLRDNDIPLMTL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 742463198 298 SSHKGTTLSKVS-LPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAE 360
Cdd:cd18108 80 DADGDVPVKELGdRPDRLALVFGSEKGGPSGLFEEAAAGTVSIPMSSSTESLNVSVSAGIALHE 143
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
132-204 |
5.71e-09 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 52.24 E-value: 5.71e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 742463198 132 VYGENACQALFLSRPEaIVRGWFLQEV-TPRFREALRWMAANRKAYHVVEDDELIRASGTEHHGGVCFLIKKRR 204
Cdd:pfam08032 2 IYGRHAVLEALKSGPE-IKKLYLTEGRrDPRLKELLKLAKERGIKVEEVDRKKLDKLSGTANHQGVVAEVKPYE 74
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
132-202 |
4.09e-07 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 46.76 E-value: 4.09e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 742463198 132 VYGENACQALfLSRPEAIVRGWFLQEVTPRFREALRWMAANRKAYHVVEDDELIRASGTEHHGGVCFLIKK 202
Cdd:smart00967 1 IEGRHAVEEA-LKSGRRIKELYLTEGRAERLKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
230-365 |
1.56e-06 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 47.34 E-value: 1.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 230 PHNLGGIMRSCAHFGVKGVLVR-------DasqlesgAAVRTAegG---AEHVKAISADGLVDALAQFRaaGYTIVTTSS 299
Cdd:COG0219 12 PQNTGNIIRLCAATGARLHLIEplgfsldD-------KKLKRA--GldyWELVDLTVHDSWEAFLEALP--GGRLFLFTT 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 742463198 300 HKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQG-DVKVSIDGTGNVESLNISVATGILLAEWWRQN 365
Cdd:COG0219 81 KGTKPYTDVDYQPGDVLLFGRETAGLPEEVLAAPaDQRLRIPMRPGVRSLNLSNAVAIVLYEALRQL 147
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
230-360 |
1.27e-05 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 44.55 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 230 PHNLGGIMRSCAHFGVKGVLVR-------DASQLESGAavrtaeGGAEHVKaISADGLVDALAQFRAAGYTIVTTSSHKG 302
Cdd:cd18106 11 PGNLGSILRSAAAAGCSKVLLTkgcvdpwEPKVLRAGA------GAHFRLP-IYGNLSWDDIPNYLPDDSKVFLADNNLP 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 742463198 303 TTL--SKVSLPAKTVIVLGQEGDGLSDNAWQ----QGDVKVSIDGTGNVESLNISVATGILLAE 360
Cdd:cd18106 84 VQPydSIDYCSGPIVLVIGGETHGVSPEAYKlahsTGGSRVHIPLANGVDSLNSAVAASILLFE 147
|
|
| SpoU-like |
cd18098 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
220-358 |
2.54e-05 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349971 Cd Length: 138 Bit Score: 43.41 E-value: 2.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 220 CVLALEDVGNPHNLGGIMRSCAHFGVKGVLVRDASQLESGAAVRTAEgGAEHVKAISADGLvDALAQFRAAGYTIVTTS- 298
Cdd:cd18098 1 FAIGIENPKTPKNVGTLWRAAGCLGASFVFTIGARYKRRKQSTDTSK-AWRHIPLFHYDDL-EDLAEPLPFGAVLVAVEl 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 299 SHKGTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGnveSLNISVATGILL 358
Cdd:cd18098 79 TEGATPLPDFKHPDRAVYLLGPEDGGLPQEVLARCHHVVYLPTRG---SLNVAVAGSIVL 135
|
|
| TrmJ |
COG0565 |
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ... |
232-364 |
1.44e-03 |
|
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ribosomal structure and biogenesis]; tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440331 [Multi-domain] Cd Length: 237 Bit Score: 39.71 E-value: 1.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742463198 232 NLGGIMRSCAHFGVKG-VLVRDASQLeSGAAVRTAeGGAEHV--KAISADGLVDALAQFRaagYTIVTTS-SHK------ 301
Cdd:COG0565 16 NIGAAARAMKNFGLSDlRLVNPRGWP-DEEARAMA-SGADDVleNARVVDTLEEALADCD---LVVGTTArPRElrkpvl 90
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 742463198 302 -----GTTLSKVSLPAKTVIVLGQEGDGLSDNAWQQGDVKVSIDGTGNVESLNISVATGILLAEWWRQ 364
Cdd:COG0565 91 tpreaAEELLARAAGGKVALVFGRERSGLTNEELALCDALVTIPTNPEYPSLNLAQAVQVVAYELRKA 158
|
|
| |
