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Conserved domains on  [gi|746157850|ref|WP_039218392|]
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APC family permease [Burkholderia multivorans]

Protein Classification

APC family permease( domain architecture ID 11425014)

APC (amino acid/polyamine/organocation) family permease is involved in the uptake of a specific amino acid and/or polyamine substrate with the concomitant import of a proton

Gene Ontology:  GO:0016020|GO:0055085|GO:0022857|GO:0015171|GO:0006865
PubMed:  23177982|24038584|25043943|10931886
SCOP:  4006243
TCDB:  2.A.3.1|2.A.3

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
5-327 3.28e-41

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


:

Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 151.20  E-value: 3.28e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   5 ADSPAAHHGGSLTIFQGAALYIGAVLGTGVIALPALAADVAGPASLLAWAALVVLSAPLAATFAALGARYPDAGGVSTYA 84
Cdd:COG0531    2 SRGESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  85 RRAFGPKAAAVVGWCFYFAVPAGAPAAAMFGGAYVAAVTGGGQTTViaTAAALIAIVSAANAFGVTVSGRMQLVLSALLV 164
Cdd:COG0531   82 RRALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGSVL--IALVLILLLTLLNLRGVKESAKVNNILTVLKL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 165 TLLLAAVLASAPHARTANLHPFAPH--GWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLYLS 242
Cdd:COG0531  160 LVLLLFIVVGLFAFDPANFTPFLPAggGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYIL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 243 VAAASVMVLGPSA-GASGAPLAELIAGGIGGHAQVLATAAALLLTLGTMNAYFAGAAKLGAALGRDGALPAWLAQGSQVG 321
Cdd:COG0531  240 VSLALTGVVPYDElAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMARDGLLPKVFAKVHPRF 319


                 ....*.
gi 746157850 322 GVPRRS 327
Cdd:COG0531  320 GTPVNA 325
 
Name Accession Description Interval E-value
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
5-327 3.28e-41

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 151.20  E-value: 3.28e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   5 ADSPAAHHGGSLTIFQGAALYIGAVLGTGVIALPALAADVAGPASLLAWAALVVLSAPLAATFAALGARYPDAGGVSTYA 84
Cdd:COG0531    2 SRGESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  85 RRAFGPKAAAVVGWCFYFAVPAGAPAAAMFGGAYVAAVTGGGQTTViaTAAALIAIVSAANAFGVTVSGRMQLVLSALLV 164
Cdd:COG0531   82 RRALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGSVL--IALVLILLLTLLNLRGVKESAKVNNILTVLKL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 165 TLLLAAVLASAPHARTANLHPFAPH--GWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLYLS 242
Cdd:COG0531  160 LVLLLFIVVGLFAFDPANFTPFLPAggGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYIL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 243 VAAASVMVLGPSA-GASGAPLAELIAGGIGGHAQVLATAAALLLTLGTMNAYFAGAAKLGAALGRDGALPAWLAQGSQVG 321
Cdd:COG0531  240 VSLALTGVVPYDElAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMARDGLLPKVFAKVHPRF 319


                 ....*.
gi 746157850 322 GVPRRS 327
Cdd:COG0531  320 GTPVNA 325
PRK11021 PRK11021
putative transporter; Provisional
 16-364 2.29e-34

putative transporter; Provisional


Pssm-ID: 236823 [Multi-domain]  Cd Length: 410  Bit Score: 131.96  E-value: 2.29e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  16 LTIFQGAALYIGAVLGTGVIALPALAADVAGPASLLAWAALVVLSAPLAATFAALGARYPDAGGVSTYARRAFGPKAAAV 95
Cdd:PRK11021   1 LGLWQGIGLLSTSLLGTGVFAVPALAALVAGNNSLWAWPLLILLIFPIAIVFARLGRHFPHAGGPAHFVGMAFGPRLGRV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  96 VGWCFYFAVPAGAPAAAMFGGAYVAAVTGGGQTTVIATAAALIAIVSAANAFGVTVSGRMQLVLSALLVTLLLAAVLASA 175
Cdd:PRK11021  81 TGWLFLSVIPVGLPAALQIAAGFGQALFGWSSWQLLLAELLTLALLWLLNLRGASSSANLQTVIALLIVALVVAIWWAGD 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 176 PHARTANLHPFAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLYLsvaAASVMVL---- 251
Cdd:PRK11021 161 IKPADIPFPAPGSIEWSGLFAALGVMFWCFVGIEAFAHLASEFKNPERDFPRALMIGLLLAGLVYW---ACTVVVLhfpa 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 252 GPSAGASGAPLAELIAGGIGGHAQVLATAAALLLTLGTMNAYFAGAAKLGAALGRDGALPAWLAQGSQvGGVPRRSLGAI 331
Cdd:PRK11021 238 YGDKQAAAASLPGIFVQLFGGYALWVICVIGYLACFASVNIYTQSFARLVWSQAREGRPPSYLARLSA-RGVPVNALNAV 316

                        330       340       350
                 ....*....|....*....|....*....|...
gi 746157850 332 AVLAAAALAATTLAGVGPTPLVLVTSGCFVMVY 364
Cdd:PRK11021 317 LGCCAVSILLIYALGLNLEALIAYANGIFVLIY 349
AA_permease_2 pfam13520
Amino acid permease;
16-267 5.05e-12

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 67.34  E-value: 5.05e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   16 LTIFQGAALYIGAVLGTGVIALPALAAdvAGPASLL-AWAALVVLSAPLAATFAALGARYPDAGGVSTYARRAFGPKAAA 94
Cdd:pfam13520   1 LGLLSAFALVIGSVIGSGIFVAPLVAS--GGPALIVwGWIAAIIFSLAVGLVYAELSSALPRSGGIYVYLENAFGKFVAF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   95 VVGWCFYFAVPAGAPAAAMFGGAYVAAVTG----GGQTTVIATAAALIAIVSAANAFGVTVSGRMQLVLSALLVTL---- 166
Cdd:pfam13520  79 LAGWSNWFAYVLGLASSASVAASYLLSALGpdlvPTTWLTYGIAIAILIIFAIINIRGVRESAKIQNILGILKLLLplil 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  167 ----LLAAVLASAPHARTANLHPFAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPahDMPRSAGIAVVVVGLLYLS 242
Cdd:pfam13520 159 iiilGLVTADGGGFNLLSGEWHTFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEVKKR--NVPKAIFIGVIIVGVLYIL 236

                         250       260
                  ....*....|....*....|....*
gi 746157850  243 VAAASVMVLGPSAGASGAPLAELIA 267
Cdd:pfam13520 237 VNIAFFGVVPDDEIALSSGLGQVAA 261
2A0302 TIGR00905
transporter, basic amino acid/polyamine antiporter (APA) family; This family includes several ...
 16-101 2.54e-07

transporter, basic amino acid/polyamine antiporter (APA) family; This family includes several families of antiporters that, rather commonly, are encoded next to decarboxylases that convert one of the antiporter substrates into the other. This arrangement allows a cycle that can remove proteins from the cytoplasm and thereby protect against acidic conditions. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 129983  Cd Length: 473  Bit Score: 52.75  E-value: 2.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   16 LTIFQGAALYIGAVLGTGVIALPALAADVAGP-ASLLAWAALVVLSAPLAATFAALGARYPD-AGGVSTYARRAFGPKAA 93
Cdd:TIGR00905   9 LGLFALTALVIGSMIGSGIFSLPQNLASVAGPgAVIIGWIITGVGMLALAFVFAILATKKPElDGGIYAYAREGFGPYIG 88


                  ....*...
gi 746157850   94 AVVGWCFY 101
Cdd:TIGR00905  89 FMSGWGYW 96
 
Name Accession Description Interval E-value
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
5-327 3.28e-41

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 151.20  E-value: 3.28e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   5 ADSPAAHHGGSLTIFQGAALYIGAVLGTGVIALPALAADVAGPASLLAWAALVVLSAPLAATFAALGARYPDAGGVSTYA 84
Cdd:COG0531    2 SRGESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  85 RRAFGPKAAAVVGWCFYFAVPAGAPAAAMFGGAYVAAVTGGGQTTViaTAAALIAIVSAANAFGVTVSGRMQLVLSALLV 164
Cdd:COG0531   82 RRALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGSVL--IALVLILLLTLLNLRGVKESAKVNNILTVLKL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 165 TLLLAAVLASAPHARTANLHPFAPH--GWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLYLS 242
Cdd:COG0531  160 LVLLLFIVVGLFAFDPANFTPFLPAggGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYIL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 243 VAAASVMVLGPSA-GASGAPLAELIAGGIGGHAQVLATAAALLLTLGTMNAYFAGAAKLGAALGRDGALPAWLAQGSQVG 321
Cdd:COG0531  240 VSLALTGVVPYDElAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMARDGLLPKVFAKVHPRF 319


                 ....*.
gi 746157850 322 GVPRRS 327
Cdd:COG0531  320 GTPVNA 325
PRK11021 PRK11021
putative transporter; Provisional
 16-364 2.29e-34

putative transporter; Provisional


Pssm-ID: 236823 [Multi-domain]  Cd Length: 410  Bit Score: 131.96  E-value: 2.29e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  16 LTIFQGAALYIGAVLGTGVIALPALAADVAGPASLLAWAALVVLSAPLAATFAALGARYPDAGGVSTYARRAFGPKAAAV 95
Cdd:PRK11021   1 LGLWQGIGLLSTSLLGTGVFAVPALAALVAGNNSLWAWPLLILLIFPIAIVFARLGRHFPHAGGPAHFVGMAFGPRLGRV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  96 VGWCFYFAVPAGAPAAAMFGGAYVAAVTGGGQTTVIATAAALIAIVSAANAFGVTVSGRMQLVLSALLVTLLLAAVLASA 175
Cdd:PRK11021  81 TGWLFLSVIPVGLPAALQIAAGFGQALFGWSSWQLLLAELLTLALLWLLNLRGASSSANLQTVIALLIVALVVAIWWAGD 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 176 PHARTANLHPFAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLYLsvaAASVMVL---- 251
Cdd:PRK11021 161 IKPADIPFPAPGSIEWSGLFAALGVMFWCFVGIEAFAHLASEFKNPERDFPRALMIGLLLAGLVYW---ACTVVVLhfpa 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 252 GPSAGASGAPLAELIAGGIGGHAQVLATAAALLLTLGTMNAYFAGAAKLGAALGRDGALPAWLAQGSQvGGVPRRSLGAI 331
Cdd:PRK11021 238 YGDKQAAAASLPGIFVQLFGGYALWVICVIGYLACFASVNIYTQSFARLVWSQAREGRPPSYLARLSA-RGVPVNALNAV 316

                        330       340       350
                 ....*....|....*....|....*....|...
gi 746157850 332 AVLAAAALAATTLAGVGPTPLVLVTSGCFVMVY 364
Cdd:PRK11021 317 LGCCAVSILLIYALGLNLEALIAYANGIFVLIY 349
AA_permease_2 pfam13520
Amino acid permease;
16-267 5.05e-12

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 67.34  E-value: 5.05e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   16 LTIFQGAALYIGAVLGTGVIALPALAAdvAGPASLL-AWAALVVLSAPLAATFAALGARYPDAGGVSTYARRAFGPKAAA 94
Cdd:pfam13520   1 LGLLSAFALVIGSVIGSGIFVAPLVAS--GGPALIVwGWIAAIIFSLAVGLVYAELSSALPRSGGIYVYLENAFGKFVAF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   95 VVGWCFYFAVPAGAPAAAMFGGAYVAAVTG----GGQTTVIATAAALIAIVSAANAFGVTVSGRMQLVLSALLVTL---- 166
Cdd:pfam13520  79 LAGWSNWFAYVLGLASSASVAASYLLSALGpdlvPTTWLTYGIAIAILIIFAIINIRGVRESAKIQNILGILKLLLplil 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  167 ----LLAAVLASAPHARTANLHPFAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPahDMPRSAGIAVVVVGLLYLS 242
Cdd:pfam13520 159 iiilGLVTADGGGFNLLSGEWHTFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEVKKR--NVPKAIFIGVIIVGVLYIL 236

                         250       260
                  ....*....|....*....|....*
gi 746157850  243 VAAASVMVLGPSAGASGAPLAELIA 267
Cdd:pfam13520 237 VNIAFFGVVPDDEIALSSGLGQVAA 261
GerAB COG5902
Spore germination receptor GerABC, GerB subunit (amino acid transporter) [Cell cycle control, ...
 14-253 7.82e-10

Spore germination receptor GerABC, GerB subunit (amino acid transporter) [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444604  Cd Length: 365  Bit Score: 60.21  E-value: 7.82e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  14 GSLTIFQGAALYIGAVLGTGVIALPALAADVAGPASLLA--WAALVVLsaPLAATFAALGARYPDAGGVStYARRAFGPK 91
Cdd:COG5902    4 GKISARQLFFLIILTIIGVGILTLPRLLAKIAGQDAWISvlLAGLIGL--LLALIIVKLLKRFPGKTLVE-ISEKILGKW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  92 AAAVVGWcFYFAVPAGAPAAAMFGGAYVAAVTGGGQTTVIATAAALIAIVSAANAFGVTVSGRMQLVLSALLVTLLLAAV 171
Cdd:COG5902   81 LGKLLGL-LYILYFLLIAALVLREFGEFIKTTLLPETPIWVIILLFLLVAVYAVRGGIEVIARVAEILFPLILILLLLLL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 172 LASAPHARTANLHPFAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHdMPRSAGIAVVVVGLLYLSVAAASVMVL 251
Cdd:COG5902  160 LLSLPEIDFSNLLPVLENGLKPILKGALPTSFPFGGFEILLMLYPYVKKKKK-AKKAALIGILISGLLLTLVVLVSIGVF 238


                 ..
gi 746157850 252 GP 253
Cdd:COG5902  239 GP 240
2A0302 TIGR00905
transporter, basic amino acid/polyamine antiporter (APA) family; This family includes several ...
 16-101 2.54e-07

transporter, basic amino acid/polyamine antiporter (APA) family; This family includes several families of antiporters that, rather commonly, are encoded next to decarboxylases that convert one of the antiporter substrates into the other. This arrangement allows a cycle that can remove proteins from the cytoplasm and thereby protect against acidic conditions. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 129983  Cd Length: 473  Bit Score: 52.75  E-value: 2.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   16 LTIFQGAALYIGAVLGTGVIALPALAADVAGP-ASLLAWAALVVLSAPLAATFAALGARYPD-AGGVSTYARRAFGPKAA 93
Cdd:TIGR00905   9 LGLFALTALVIGSMIGSGIFSLPQNLASVAGPgAVIIGWIITGVGMLALAFVFAILATKKPElDGGIYAYAREGFGPYIG 88


                  ....*...
gi 746157850   94 AVVGWCFY 101
Cdd:TIGR00905  89 FMSGWGYW 96
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 16-315 3.60e-06

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 48.98  E-value: 3.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   16 LTIFQGAALYIGAVLGTGVIALPALAADVAGPA--SLLAWAALVVLSAPLAATFAALGARYPDAGGVSTYARRAFGPKAA 93
Cdd:TIGR00911  44 ITLLSGVGIIVGTIIGSGIFVSPKGVLKNAGSVglALIMWAVCGIFSIVGALVYAELGTTIPKSGGEYNYILEVFGPLLA 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   94 AVVGWC-FYFAVPAGAPAAAMFGGAYV-------AAVTGGGQTTVIATAAALIAIVsaaNAFGVTVSGRMQLVLSALLVT 165
Cdd:TIGR00911 124 FLRLWIeLLVIRPGSQAVNALNFAIYIltpvfpdCEVPEWAIRLVAVLCVLLLTLV---NCLSVKWATRVQDIFTACKLL 200

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  166 LLLAAVLASAPHARTANLHPFAPHGWLAVGQAAALLV--------WSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVG 237
Cdd:TIGR00911 201 ALLLIIITGWVQLGKGGVESLNPKNAFEGTETSAGGIvlafysgiWAYGGWNYLNFVTEEVKNPYRTLPIAIIISMPIVT 280

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 746157850  238 LLYLSVAAASVMVLGPSAGASGAPLAELIAGGIGGHAQVLATAAALLLTLGTMNAYFAGAAKLGAALGRDGALPAWLA 315
Cdd:TIGR00911 281 FIYVLTNIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMPALVGLSCFGSVNGSLFSSSRLFFVGGREGHLPSLLS 358
AA_permease pfam00324
Amino acid permease;
26-255 1.02e-05

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 47.70  E-value: 1.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   26 IGAVLGTGVIALPALAADVAGPAS-LLAWAALVVLSAPLAATFAALGARYPDAGGVSTYARRAFGPKAAAVVGWCFYFAV 104
Cdd:pfam00324   7 LGGVIGTGLFVGSGSVLGQAGPAGaLLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGWNYWLSW 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  105 PAGAPAAAMFGGAYVA-AVTGGGQTTVIATAAALIAIVSAANAFGVTVSGRMQ------------------LVLSALLVT 165
Cdd:pfam00324  87 ITVLALELTAASILIQfWELVPDIPYLWVWGAVFLVLLTIINLVGVKWYGEAEfwfalikiiaiigfiivgIILLSGGNP 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  166 LLLAAVLASAPHARTANLHPFAPHGWLAVGQAAALlvwSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLYLSVAA 245
Cdd:pfam00324 167 NDGAIFRYLGDNGGKNNFPPGFGKGFISVFVIAFF---AFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYILSLL 243

                         250
                  ....*....|
gi 746157850  246 ASVMVLGPSA 255
Cdd:pfam00324 244 AIGLLVPWND 253
PRK10644 PRK10644
arginine/agmatine antiporter;
27-90 1.24e-04

arginine/agmatine antiporter;


Pssm-ID: 182613 [Multi-domain]  Cd Length: 445  Bit Score: 44.01  E-value: 1.24e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 746157850  27 GAVLGTGVIALPALAADVAGpASLLAWAALVVLSAPLAATFAALGARYPDAGGVSTYARRAFGP 90
Cdd:PRK10644  21 GNIMGSGVFLLPANLASTGG-IAIYGWLVTIIGALGLSMVYAKMSSLDPSPGGSYAYARRCFGP 83
PRK10197 PRK10197
GABA permease;
24-101 2.60e-04

GABA permease;


Pssm-ID: 182297  Cd Length: 446  Bit Score: 43.07  E-value: 2.60e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 746157850  24 LYIGAVLGTGVIALPALAADVAGPASLLAWAALVVLSAPLAATFAALGARYPDAGGVSTYARRAFGPKAAAVVGWCFY 101
Cdd:PRK10197   2 LSIAGVIGASLFVGSSVAIAEAGPAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYW 79
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
 16-246 5.48e-04

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 42.11  E-value: 5.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   16 LTIFQGAALYIGAVLGTGVIALPALAA-DVAGPASLLAWAALVVLSAPLAATFAALGARYPDAGGVSTYARRAFGPKAAA 94
Cdd:TIGR00906  30 LTTWDLMALGIGSTIGAGIYVLTGEVArNDSGPAIVLSFLISGLAAVLSGFCYAEFGARVPKAGSAYLYSYVTVGELWAF 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850   95 VVGWCFYFAVPAGAPAAAMFGGAYVAAVTG----------------GGQTTVIATAAALIAIVSAANAFGVTVSGRMQLV 158
Cdd:TIGR00906 110 ITGWNLILEYVIGTAAVARSWSAYFDELLNkqigqfrrtyfklnydGLAEYPDFFAVCLILLLAVLLSFGVKESAWVNKI 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  159 LSALLVTLLLAAVLASAPHARTANLHP--------FAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAG 230
Cdd:TIGR00906 190 FTAINILVLLFVIIAGFTKADVANWSIteekgaggFMPYGFTGVLSGAATCFFAFIGFDAIATTGEEVKNPQRAIPIGIV 269

                         250
                  ....*....|....*.
gi 746157850  231 IAVVVVGLLYLSVAAA 246
Cdd:TIGR00906 270 TSLLVCFVAYFLMSAA 285
PRK10238 PRK10238
aromatic amino acid transporter AroP;
26-251 1.25e-03

aromatic amino acid transporter AroP;


Pssm-ID: 182324 [Multi-domain]  Cd Length: 456  Bit Score: 41.09  E-value: 1.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  26 IGAVLGTGVIALPALAADVAGPASLLAWAALVVLSAPLAATFAALGARYPDAGGVSTYARRAFGPKAAAVVGWCFYFAVP 105
Cdd:PRK10238  24 LGGAIGTGLFLGSASVIQSAGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVLYV 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 106 AGAPAAAMFGGAYVAAVTGggQTTVIATAAALIAIVSAANAFGVTVSGRMQLVLSALLVTLLLAA---------VLASAP 176
Cdd:PRK10238 104 LVAMAELTAVGKYIQFWYP--EIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKVIAVVAMiifggwllfSGNGGP 181

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 746157850 177 HARTANLHP---FAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLYLSVAAASVMVL 251
Cdd:PRK10238 182 QATVSNLWDqggFLPHGFTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLM 259
frlA PRK11357
amino acid permease;
23-292 1.87e-03

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 40.22  E-value: 1.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  23 ALYIGAVLGTGVIALPALAADVAGPASLLAWAALV--VLSAPLAATFAALGARYPDAGGVSTYARRAFGPKAAAVVGW-C 99
Cdd:PRK11357  17 AIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLAFVIggLIVIPQMCVYAELSTAYPENGADYVYLKNAGSRPLAFLSGWaS 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 100 FYFAVPAGAPAAAMFGGAYVAAVTGGGQTTVIATAAALIAIVSAANAFGVTVSGRMQLVLSALLVTLLLAAVLASAPHAR 179
Cdd:PRK11357  97 FWANDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAKIIPFTIVIGLGIFWFK 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 180 TANLHPFAPHGWLAVGQAAALLV------WSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLY--LSVAAASVMVL 251
Cdd:PRK11357 177 AENFAAPTTTAIGATGSFMALLAgisatsWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVLVLYtlLALVISGLMPF 256

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 746157850 252 GPSAgASGAPLAELIA--GGIGGHAQVLATAAALLLTLGTMNA 292
Cdd:PRK11357 257 DKLA-NSETPISDALTwiPALGSTAGIFVAITAMIVILGSLSS 298
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
26-251 2.15e-03

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 40.10  E-value: 2.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  26 IGAVLGTGVIALPALAADVAGPASLLAWAalvvlsapLAATFA-----ALG---ARYPDAGGVSTYARRAFGPKAAAVVG 97
Cdd:COG1113   27 LGGAIGTGLFLGSGKAIALAGPAVLLSYL--------IAGLIVflvmrALGemaVANPVSGSFSDYAREYLGPWAGFVTG 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  98 WCFYFAVPAGApaaamfggayVAAVTGGG--------QTTVIATAAALIAIVSAANAFGVTVSGRMQ------------L 157
Cdd:COG1113   99 WLYWFFWVLVG----------MAEATAVGiylqfwfpDVPQWVWALVFLVLLTAINLLSVKLFGEFEfwfalikvvaivA 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 158 VLSALLVTLLLAAVLASAPHARTANL---HPFAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAGIAVV 234
Cdd:COG1113  169 FIVVGLLLIFFGFGLPGGPPAGLSNLwdhGGFFPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTIPKAINSVIW 248

                        250
                 ....*....|....*..
gi 746157850 235 VVGLLYlsVAAASVMVL 251
Cdd:COG1113  249 RILLFY--VGSLFVILA 263
PRK15049 PRK15049
L-asparagine permease;
26-259 2.67e-03

L-asparagine permease;


Pssm-ID: 185009  Cd Length: 499  Bit Score: 39.99  E-value: 2.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850  26 IGAVLGTGVIALPALAADVAGPASLLAWAALVVLSAPLAATFAALGARYPDAGGVSTYARRAFGPKAAAVVGWCFYFAVP 105
Cdd:PRK15049  40 IGGAIGTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFINWA 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 106 AGAPAAAMFGGAYVAAVTGGGQTTVIATAAALIAIVSAANAFGVTVSGRMQ--------LVLSALLVTLLLAAVLASAPH 177
Cdd:PRK15049 120 MTGIVDITAVALYMHYWGAFGGVPQWVFALAALTIVGTMNMIGVKWFAEMEfwfalikvLAIVTFLVVGTVFLGSGQPLD 199

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746157850 178 ARTANLH------PFAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLYLSVAAASVMVL 251
Cdd:PRK15049 200 GNTTGFHlitdngGFFPHGLLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLVMLL 279


                 ....*...
gi 746157850 252 GPSAGASG 259
Cdd:PRK15049 280 PWSAYQAG 287
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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