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Conserved domains on  [gi|746208302|ref|WP_039263764|]
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MULTISPECIES: protein lysine acetyltransferase [Enterobacter]

Protein Classification

bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase( domain architecture ID 11437151)

bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase containing an N-terminal domain similar to ADP-forming acetate--CoA ligase that catalyzes the formation of acetate and ATP from acetyl-CoA by using ADP and phosphate, and a C-terminal domain that may catalyze the transfer of an acetyl group from acetyl-CoA to a substrate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PatZN COG1042
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
1-702 0e+00

Acyl-CoA synthetase (NDP forming) [Energy production and conversion];


:

Pssm-ID: 440664 [Multi-domain]  Cd Length: 708  Bit Score: 887.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302   1 MSQRGLEALLRPKSIAVIGASMKPDRAGYLMMRNLLAGGFNGPVMPVTPSYKAVQGVLAWPDVQSLPFVPDLAVLCTNAK 80
Cdd:COG1042    1 MSTRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  81 RNPELLESLGKKGCKTCIILSSP--------PEQKAELLACASRYQMRILGPNSLGLLAPWQGLNASFSPVPIRKGKLAF 152
Cdd:COG1042   81 TVPDVVEECGEKGVKAAVVISAGfaetgeegAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPVPPLPGNIAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 153 ISQSAAVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDFLARDGKTSAILLYLEHLSDARRFVSAARSASRNKPILV 232
Cdd:COG1042  161 VSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAARGKPVVV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 233 IKSGRSPAAQHLLHSHSGM----DPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGEKLMIVSNGAAPAALALDEL 308
Cdd:COG1042  241 LKSGRSEAGARAAASHTGAlagsDAVYDAAFRRAGVIRVDDLEELFDAAEALARQPPPRGRRLAIVTNSGGPGVLAADAL 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 309 WRRFGKLATLSEETLQRLKEALPTSVTPGNPLDLRDDASSDRYIRAISILLDSQDFDALMIIHSPSAVAPGSESARALID 388
Cdd:COG1042  321 EDLGLELAELSEETQAALRAVLPPFASVGNPVDITGDADPERYAAALEALLADPNVDAVLVILTPTAMTDPEEVAEALIE 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 389 AVRNHPRgkyvTLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLRETPAlPGNLTANTVDVHR 468
Cdd:COG1042  401 AAKGSGK----PVLASWMGGDSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPA-SEDFDPDRERARA 475

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 469 LLQQAIEEGATSLDTHEVQPILGSYGMQTLPTWIASDSAEAVHIAEQIGYPVALKLRSPDIPHKSDVQGVMLYLRTATEV 548
Cdd:COG1042  476 IIEAALAEGRGVLTEAEAKALLAAYGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRDAEAV 555

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 549 QQAADAIFDRVKMAWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAVVALPPLNMNLARY 628
Cdd:COG1042  556 RAAFEEILARVRAARPDARIDGVLVQPMVP--GGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNEALARE 633

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 746208302 629 LIIQAIKSKKIRGRSALRPLDIAGLSQFLVQVSNLIVDCAEIQRLDIHPLLASGNEFTALDVTLDIAPFEGDRE 702
Cdd:COG1042  634 MIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLPEILELDINPLLVVPEGVVAVDARIRLAPPAPPAP 707
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 722-863 7.23e-15

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 73.49  E-value: 7.23e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 722 NGERALFRPILPEDEPQLRAFISQvtKEDLYYRYFSEIN-EFTHDDLANMTQIDYDREMAFVAVRRSDKGdEILGVTRAI 800
Cdd:COG1670    4 ETERLRLRPLRPEDAEALAELLND--PEVARYLPGPPYSlEEARAWLERLLADWADGGALPFAIEDKEDG-ELIGVVGLY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 746208302 801 S-DPDNVDAEFAVLVRSDLKGLGLGRRLLEKLISYTRDH-GLLRLNGITMPNNRGMVTLARKLGF 863
Cdd:COG1670   81 DiDRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEElGLHRVEAEVDPDNTASIRVLEKLGF 145
 
Name Accession Description Interval E-value
PatZN COG1042
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
1-702 0e+00

Acyl-CoA synthetase (NDP forming) [Energy production and conversion];


Pssm-ID: 440664 [Multi-domain]  Cd Length: 708  Bit Score: 887.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302   1 MSQRGLEALLRPKSIAVIGASMKPDRAGYLMMRNLLAGGFNGPVMPVTPSYKAVQGVLAWPDVQSLPFVPDLAVLCTNAK 80
Cdd:COG1042    1 MSTRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  81 RNPELLESLGKKGCKTCIILSSP--------PEQKAELLACASRYQMRILGPNSLGLLAPWQGLNASFSPVPIRKGKLAF 152
Cdd:COG1042   81 TVPDVVEECGEKGVKAAVVISAGfaetgeegAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPVPPLPGNIAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 153 ISQSAAVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDFLARDGKTSAILLYLEHLSDARRFVSAARSASRNKPILV 232
Cdd:COG1042  161 VSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAARGKPVVV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 233 IKSGRSPAAQHLLHSHSGM----DPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGEKLMIVSNGAAPAALALDEL 308
Cdd:COG1042  241 LKSGRSEAGARAAASHTGAlagsDAVYDAAFRRAGVIRVDDLEELFDAAEALARQPPPRGRRLAIVTNSGGPGVLAADAL 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 309 WRRFGKLATLSEETLQRLKEALPTSVTPGNPLDLRDDASSDRYIRAISILLDSQDFDALMIIHSPSAVAPGSESARALID 388
Cdd:COG1042  321 EDLGLELAELSEETQAALRAVLPPFASVGNPVDITGDADPERYAAALEALLADPNVDAVLVILTPTAMTDPEEVAEALIE 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 389 AVRNHPRgkyvTLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLRETPAlPGNLTANTVDVHR 468
Cdd:COG1042  401 AAKGSGK----PVLASWMGGDSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPA-SEDFDPDRERARA 475

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 469 LLQQAIEEGATSLDTHEVQPILGSYGMQTLPTWIASDSAEAVHIAEQIGYPVALKLRSPDIPHKSDVQGVMLYLRTATEV 548
Cdd:COG1042  476 IIEAALAEGRGVLTEAEAKALLAAYGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRDAEAV 555

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 549 QQAADAIFDRVKMAWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAVVALPPLNMNLARY 628
Cdd:COG1042  556 RAAFEEILARVRAARPDARIDGVLVQPMVP--GGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNEALARE 633

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 746208302 629 LIIQAIKSKKIRGRSALRPLDIAGLSQFLVQVSNLIVDCAEIQRLDIHPLLASGNEFTALDVTLDIAPFEGDRE 702
Cdd:COG1042  634 MIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLPEILELDINPLLVVPEGVVAVDARIRLAPPAPPAP 707
AcCoA-syn-alpha TIGR02717
acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it ...
 6-443 1.49e-135

acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.


Pssm-ID: 131764 [Multi-domain]  Cd Length: 447  Bit Score: 412.09  E-value: 1.49e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302    6 LEALLRPKSIAVIGASMKPDRAGYLMMRNLLAGGFNGPVMPVTPSYKAVQGVLAWPDVQSLPFVPDLAVLCTNAKRNPEL 85
Cdd:TIGR02717   1 LEHLFNPKSVAVIGASRDPGKVGYAIMKNLIEGGYKGKIYPVNPKAGEILGVKAYPSVLEIPDPVDLAVIVVPAKYVPQV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302   86 LESLGKKGCKTCIILSS--------PPEQKAELLACASRYQMRILGPNSLGLLAPWQGLNASFSPVPIRKGKLAFISQSA 157
Cdd:TIGR02717  81 VEECGEKGVKGAVVITAgfkevgeeGAELEQELVEIARKYGMRLLGPNCLGIINTHIKLNATFAPTMPKKGGIAFISQSG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  158 AVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDFLARDGKTSAILLYLEHLSDARRFVSAARSASRNKPILVIKSGR 237
Cdd:TIGR02717 161 ALLTALLDWAEKNGVGFSYFVSLGNKADIDESDLLEYLADDPDTKVILLYLEGIKDGRKFLKTAREISKKKPIVVLKSGT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  238 SPAAQHLLHSHSGM----DPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGEKLMIVSNGAAPAALALDELWRRFG 313
Cdd:TIGR02717 241 SEAGAKAASSHTGAlagsDEAYDAAFKQAGVIRADSIEELFDLARLLSNQPLPKGNRVAIITNAGGPGVIATDACEENGL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  314 KLATLSEETLQRLKEALPTSVTPGNPLDLRDDASSDRYIRAISILLDSQDFDALMIIHSPSAVAPGSESARALIDAVRNH 393
Cdd:TIGR02717 321 ELAELSEATKNKLRNILPPEASIKNPVDVLGDATPERYAKALKTVAEDENVDGVVVVLTPTAMTDPEEVAKGIIEGAKKS 400

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 746208302  394 PRgkyVTLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYR 443
Cdd:TIGR02717 401 NE---KPVVAGFMGGKSVDPAKRILEENGIPNYTFPERAVKALSALYRYA 447
ATP-grasp_5 pfam13549
ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent ...
 472-690 4.90e-87

ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent carboxylate-amine ligase activity.


Pssm-ID: 463918 [Multi-domain]  Cd Length: 221  Bit Score: 276.28  E-value: 4.90e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  472 QAIEEGATSLDTHEVQPILGSYGMQTLPTWIASDSAEAVHIAEQIGYPVALKLRSPDIPHKSDVQGVMLYLRTATEVQQA 551
Cdd:pfam13549   1 KALAEGRTVLTEPEAKALLAAYGIPVVPTRLARSPEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRSAEAVRAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  552 ADAIFDRVKMAWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAVVALPPLNMNLARYLiI 631
Cdd:pfam13549  81 YEEILERVRRYRPDARIEGVLVQPMAP--GGRELIVGVTRDPQFGPVIMFGLGGIAVEVLKDVAFRLPPLNMTLAREM-I 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  632 QAIKSKKI-RGRSALRPLDIAGLSQFLVQVSNLIVDCAEIQRLDIHPLLASGNEFTALDV 690
Cdd:pfam13549 158 RRTRAYKLlKGYRGEPPADLDALEDVLVRVSQLVIDFPEIRELDINPLLADEDGVVALDA 217
CoA_binding smart00881
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 9-102 1.02e-15

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 214881 [Multi-domain]  Cd Length: 100  Bit Score: 73.31  E-value: 1.02e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302     9 LLRP-KSIAVIGASMKPDRAGYLMMRNLLAGG--FNGPVMP--VTPSYkavQGVLAWPDVQSLPFV--PDLAVLCTNAKR 81
Cdd:smart00881   1 LLNPnTSVAVVGASGNLGSFGLAVMRNLLEYGtkFVGGVYPgkVGPKV---DGVPVYDSVAEAPEEtgVDVAVIFVPAEA 77

                           90       100
                   ....*....|....*....|.
gi 746208302    82 NPELLESLGKKGCKTCIILSS 102
Cdd:smart00881  78 APDAIDEAIEAGIKGIVVITE 98
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 722-863 7.23e-15

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 73.49  E-value: 7.23e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 722 NGERALFRPILPEDEPQLRAFISQvtKEDLYYRYFSEIN-EFTHDDLANMTQIDYDREMAFVAVRRSDKGdEILGVTRAI 800
Cdd:COG1670    4 ETERLRLRPLRPEDAEALAELLND--PEVARYLPGPPYSlEEARAWLERLLADWADGGALPFAIEDKEDG-ELIGVVGLY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 746208302 801 S-DPDNVDAEFAVLVRSDLKGLGLGRRLLEKLISYTRDH-GLLRLNGITMPNNRGMVTLARKLGF 863
Cdd:COG1670   81 DiDRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEElGLHRVEAEVDPDNTASIRVLEKLGF 145
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 750-863 3.21e-09

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 55.60  E-value: 3.21e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  750 DLYYRYFSEinEFTHDDLANMTQIDYDREMAFVAVRRsdkGDEILGVTRA--ISDPDNVDAEFAVLVRSDLKGLGLGRRL 827
Cdd:pfam00583   6 ELLSEEFPE--PWPDEPLDLLEDWDEDASEGFFVAEE---DGELVGFASLsiIDDEPPVGEIEGLAVAPEYRGKGIGTAL 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 746208302  828 LEKLISYTRDHGLLRLNGITMPNNRGMVTLARKLGF 863
Cdd:pfam00583  81 LQALLEWARERGCERIFLEVAADNLAAIALYEKLGF 116
 
Name Accession Description Interval E-value
PatZN COG1042
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
1-702 0e+00

Acyl-CoA synthetase (NDP forming) [Energy production and conversion];


Pssm-ID: 440664 [Multi-domain]  Cd Length: 708  Bit Score: 887.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302   1 MSQRGLEALLRPKSIAVIGASMKPDRAGYLMMRNLLAGGFNGPVMPVTPSYKAVQGVLAWPDVQSLPFVPDLAVLCTNAK 80
Cdd:COG1042    1 MSTRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  81 RNPELLESLGKKGCKTCIILSSP--------PEQKAELLACASRYQMRILGPNSLGLLAPWQGLNASFSPVPIRKGKLAF 152
Cdd:COG1042   81 TVPDVVEECGEKGVKAAVVISAGfaetgeegAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPVPPLPGNIAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 153 ISQSAAVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDFLARDGKTSAILLYLEHLSDARRFVSAARSASRNKPILV 232
Cdd:COG1042  161 VSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAARGKPVVV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 233 IKSGRSPAAQHLLHSHSGM----DPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGEKLMIVSNGAAPAALALDEL 308
Cdd:COG1042  241 LKSGRSEAGARAAASHTGAlagsDAVYDAAFRRAGVIRVDDLEELFDAAEALARQPPPRGRRLAIVTNSGGPGVLAADAL 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 309 WRRFGKLATLSEETLQRLKEALPTSVTPGNPLDLRDDASSDRYIRAISILLDSQDFDALMIIHSPSAVAPGSESARALID 388
Cdd:COG1042  321 EDLGLELAELSEETQAALRAVLPPFASVGNPVDITGDADPERYAAALEALLADPNVDAVLVILTPTAMTDPEEVAEALIE 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 389 AVRNHPRgkyvTLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLRETPAlPGNLTANTVDVHR 468
Cdd:COG1042  401 AAKGSGK----PVLASWMGGDSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPA-SEDFDPDRERARA 475

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 469 LLQQAIEEGATSLDTHEVQPILGSYGMQTLPTWIASDSAEAVHIAEQIGYPVALKLRSPDIPHKSDVQGVMLYLRTATEV 548
Cdd:COG1042  476 IIEAALAEGRGVLTEAEAKALLAAYGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRDAEAV 555

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 549 QQAADAIFDRVKMAWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAVVALPPLNMNLARY 628
Cdd:COG1042  556 RAAFEEILARVRAARPDARIDGVLVQPMVP--GGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNEALARE 633

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 746208302 629 LIIQAIKSKKIRGRSALRPLDIAGLSQFLVQVSNLIVDCAEIQRLDIHPLLASGNEFTALDVTLDIAPFEGDRE 702
Cdd:COG1042  634 MIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLPEILELDINPLLVVPEGVVAVDARIRLAPPAPPAP 707
AcCoA-syn-alpha TIGR02717
acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it ...
 6-443 1.49e-135

acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.


Pssm-ID: 131764 [Multi-domain]  Cd Length: 447  Bit Score: 412.09  E-value: 1.49e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302    6 LEALLRPKSIAVIGASMKPDRAGYLMMRNLLAGGFNGPVMPVTPSYKAVQGVLAWPDVQSLPFVPDLAVLCTNAKRNPEL 85
Cdd:TIGR02717   1 LEHLFNPKSVAVIGASRDPGKVGYAIMKNLIEGGYKGKIYPVNPKAGEILGVKAYPSVLEIPDPVDLAVIVVPAKYVPQV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302   86 LESLGKKGCKTCIILSS--------PPEQKAELLACASRYQMRILGPNSLGLLAPWQGLNASFSPVPIRKGKLAFISQSA 157
Cdd:TIGR02717  81 VEECGEKGVKGAVVITAgfkevgeeGAELEQELVEIARKYGMRLLGPNCLGIINTHIKLNATFAPTMPKKGGIAFISQSG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  158 AVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDFLARDGKTSAILLYLEHLSDARRFVSAARSASRNKPILVIKSGR 237
Cdd:TIGR02717 161 ALLTALLDWAEKNGVGFSYFVSLGNKADIDESDLLEYLADDPDTKVILLYLEGIKDGRKFLKTAREISKKKPIVVLKSGT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  238 SPAAQHLLHSHSGM----DPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGEKLMIVSNGAAPAALALDELWRRFG 313
Cdd:TIGR02717 241 SEAGAKAASSHTGAlagsDEAYDAAFKQAGVIRADSIEELFDLARLLSNQPLPKGNRVAIITNAGGPGVIATDACEENGL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  314 KLATLSEETLQRLKEALPTSVTPGNPLDLRDDASSDRYIRAISILLDSQDFDALMIIHSPSAVAPGSESARALIDAVRNH 393
Cdd:TIGR02717 321 ELAELSEATKNKLRNILPPEASIKNPVDVLGDATPERYAKALKTVAEDENVDGVVVVLTPTAMTDPEEVAKGIIEGAKKS 400

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 746208302  394 PRgkyVTLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYR 443
Cdd:TIGR02717 401 NE---KPVVAGFMGGKSVDPAKRILEENGIPNYTFPERAVKALSALYRYA 447
ATP-grasp_5 pfam13549
ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent ...
 472-690 4.90e-87

ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent carboxylate-amine ligase activity.


Pssm-ID: 463918 [Multi-domain]  Cd Length: 221  Bit Score: 276.28  E-value: 4.90e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  472 QAIEEGATSLDTHEVQPILGSYGMQTLPTWIASDSAEAVHIAEQIGYPVALKLRSPDIPHKSDVQGVMLYLRTATEVQQA 551
Cdd:pfam13549   1 KALAEGRTVLTEPEAKALLAAYGIPVVPTRLARSPEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRSAEAVRAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  552 ADAIFDRVKMAWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAVVALPPLNMNLARYLiI 631
Cdd:pfam13549  81 YEEILERVRRYRPDARIEGVLVQPMAP--GGRELIVGVTRDPQFGPVIMFGLGGIAVEVLKDVAFRLPPLNMTLAREM-I 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  632 QAIKSKKI-RGRSALRPLDIAGLSQFLVQVSNLIVDCAEIQRLDIHPLLASGNEFTALDV 690
Cdd:pfam13549 158 RRTRAYKLlKGYRGEPPADLDALEDVLVRVSQLVIDFPEIRELDINPLLADEDGVVALDA 217
Succ_CoA_lig pfam13607
Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from ...
 147-280 6.30e-54

Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from Succinyl-CoA ligase alpha subunit and other related enzymes. A conserved histidine is involved in phosphoryl transfer.


Pssm-ID: 433345 [Multi-domain]  Cd Length: 138  Bit Score: 183.44  E-value: 6.30e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  147 KGKLAFISQSAAVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDFLARDGKTSAILLYLEHLSDARRFVSAARSASR 226
Cdd:pfam13607   1 PGNIALVSQSGALGAALLDWARSRGIGFSKFVSLGNEADVDFADLLEYLADDPETRVILLYLEGIRDGRRFLRAARRAAR 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 746208302  227 NKPILVIKSGRSPAAQHLLHSH----SGMDPAWDAAIQRAGLLRVQDTHELFSAVETL 280
Cdd:pfam13607  81 RKPVVVLKAGRSEAGARAAASHtgalAGSDAVYDAAFRQAGVIRVDDLEELFDAAEAL 138
CoA_binding_2 pfam13380
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 13-132 2.74e-28

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 433162 [Multi-domain]  Cd Length: 116  Bit Score: 109.94  E-value: 2.74e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302   13 KSIAVIGASMKPDRAGYLMMRNLLAGGFngPVMPVTPSYKAVQGVLAWPDVQSLPFVPDLAVLCTNAKRNPELLESLGKK 92
Cdd:pfam13380   1 KTIAVVGASPNPGRPGYKVARYLLEHGY--PVIPVNPKAKEILGEPVYPSLADPPEPVDLVDVFRPPEAVPEIVEEALAL 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 746208302   93 GCKTCIILSSppEQKAELLACASRYQMRILGPNSLGLLAP 132
Cdd:pfam13380  79 GAKAVWLQPG--IENEEAAAIARAAGIRVVGDRCLGVEHP 116
CoA_binding smart00881
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 9-102 1.02e-15

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 214881 [Multi-domain]  Cd Length: 100  Bit Score: 73.31  E-value: 1.02e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302     9 LLRP-KSIAVIGASMKPDRAGYLMMRNLLAGG--FNGPVMP--VTPSYkavQGVLAWPDVQSLPFV--PDLAVLCTNAKR 81
Cdd:smart00881   1 LLNPnTSVAVVGASGNLGSFGLAVMRNLLEYGtkFVGGVYPgkVGPKV---DGVPVYDSVAEAPEEtgVDVAVIFVPAEA 77

                           90       100
                   ....*....|....*....|.
gi 746208302    82 NPELLESLGKKGCKTCIILSS 102
Cdd:smart00881  78 APDAIDEAIEAGIKGIVVITE 98
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 722-863 7.23e-15

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 73.49  E-value: 7.23e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 722 NGERALFRPILPEDEPQLRAFISQvtKEDLYYRYFSEIN-EFTHDDLANMTQIDYDREMAFVAVRRSDKGdEILGVTRAI 800
Cdd:COG1670    4 ETERLRLRPLRPEDAEALAELLND--PEVARYLPGPPYSlEEARAWLERLLADWADGGALPFAIEDKEDG-ELIGVVGLY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 746208302 801 S-DPDNVDAEFAVLVRSDLKGLGLGRRLLEKLISYTRDH-GLLRLNGITMPNNRGMVTLARKLGF 863
Cdd:COG1670   81 DiDRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEElGLHRVEAEVDPDNTASIRVLEKLGF 145
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
728-863 3.15e-14

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 71.18  E-value: 3.15e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 728 FRPILPEDEPQLRAFISQVTKEDLYyRYFSEinEFTHDDLAN-MTQIDYDREMAFVAVRrsdkGDEILGVTRAIS----D 802
Cdd:COG1247    4 IRPATPEDAPAIAAIYNEAIAEGTA-TFETE--PPSEEEREAwFAAILAPGRPVLVAEE----DGEVVGFASLGPfrprP 76

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 746208302 803 PDNVDAEFAVLVRSDLKGLGLGRRLLEKLISYTRDHGLLRLNGITMPNNRGMVTLARKLGF 863
Cdd:COG1247   77 AYRGTAEESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLADNEASIALYEKLGF 137
YccU COG1832
Predicted CoA-binding protein [General function prediction only];
7-96 8.78e-11

Predicted CoA-binding protein [General function prediction only];


Pssm-ID: 441437 [Multi-domain]  Cd Length: 138  Bit Score: 60.53  E-value: 8.78e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302   7 EALLRPKSIAVIGASMKPDRAGYLMMRNLLAGGFNgpVMPVTPSYKAVQGVLAWPDVQSLPFVPDLAVLCTNAKRNPELL 86
Cdd:COG1832   11 EILKSAKTIAVVGLSPNPERPSYYVAKYLQRHGYR--VIPVNPGAKEILGEKVYASLADIPEPVDIVDVFRRSEAVPEIV 88

                         90
                 ....*....|
gi 746208302  87 ESLGKKGCKT 96
Cdd:COG1832   89 DEAIAIGAKV 98
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 750-863 3.21e-09

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 55.60  E-value: 3.21e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  750 DLYYRYFSEinEFTHDDLANMTQIDYDREMAFVAVRRsdkGDEILGVTRA--ISDPDNVDAEFAVLVRSDLKGLGLGRRL 827
Cdd:pfam00583   6 ELLSEEFPE--PWPDEPLDLLEDWDEDASEGFFVAEE---DGELVGFASLsiIDDEPPVGEIEGLAVAPEYRGKGIGTAL 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 746208302  828 LEKLISYTRDHGLLRLNGITMPNNRGMVTLARKLGF 863
Cdd:pfam00583  81 LQALLEWARERGCERIFLEVAADNLAAIALYEKLGF 116
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 725-863 1.56e-06

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 48.50  E-value: 1.56e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  725 RALFRPILPEDEPQLRAFISQvtKEDLYYRYFSEIN-EFTHDDLANMTQIDYDREMAFVAVRrsDKGDEILGVTRAIS-D 802
Cdd:pfam13302   1 RLLLRPLTEEDAEALFELLSD--PEVMRYGVPWPLTlEEAREWLARIWAADEAERGYGWAIE--LKDTGFIGSIGLYDiD 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 746208302  803 PDNVDAEFAVLVRSDLKGLGLGRRLLEKLISYT-RDHGLLRLNGITMPNNRGMVTLARKLGF 863
Cdd:pfam13302  77 GEPERAELGYWLGPDYWGKGYATEAVRALLEYAfEELGLPRLVARIDPENTASRRVLEKLGF 138
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
728-880 1.26e-05

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 45.85  E-value: 1.26e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 728 FRPILPEDEPQLRAfisqvtkedLYYRYFSEINEfthDDLANMTQIDYDREMAFVAVRrsdkGDEILGVTRAISDPDNVD 807
Cdd:COG3153    1 IRPATPEDAEAIAA---------LLRAAFGPGRE---AELVDRLREDPAAGLSLVAED----DGEIVGHVALSPVDIDGE 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 808 AEFAVL----VRSDLKGLGLGRRLLEKLISYTRDHG--LLRLNGitmpnNRGMVTLARKLGF----DVDIQLDEGIVALS 877
Cdd:COG3153   65 GPALLLgplaVDPEYRGQGIGRALMRAALEAARERGarAVVLLG-----DPSLLPFYERFGFrpagELGLTLGPDEVFLA 139


                 ...
gi 746208302 878 LSL 880
Cdd:COG3153  140 KEL 142
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 761-865 4.40e-05

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 44.27  E-value: 4.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 761 EFTHDDLANMTQIDYDREmaFVAVrrsDKGDEILGVTRAISDPDNVdAEFAVL-VRSDLKGLGLGRRLLEKLISYTRDHG 839
Cdd:COG0454   18 EALDAELKAMEGSLAGAE--FIAV---DDKGEPIGFAGLRRLDDKV-LELKRLyVLPEYRGKGIGKALLEALLEWARERG 91

                         90       100
                 ....*....|....*....|....*...
gi 746208302 840 L--LRLNgiTMPNNRGMVTLARKLGFDV 865
Cdd:COG0454   92 CtaLELD--TLDGNPAAIRFYERLGFKE 117
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 814-863 4.45e-05

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 43.11  E-value: 4.45e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 746208302 814 VRSDLKGLGLGRRLLEKLISYTRDHGLLRLNGITMPNNRGMVTLARKLGF 863
Cdd:COG0456   21 VDPEYRGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALYEKLGF 70
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 728-863 1.28e-04

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 42.67  E-value: 1.28e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 728 FRPILPEDEPQLRAFISQvtkedlyYRYFSEINEFthddlanmtqidydremaFVAVRrsdkGDEILGVTRAISDPDNVd 807
Cdd:COG1246    3 IRPATPDDVPAILELIRP-------YALEEEIGEF------------------WVAEE----DGEIVGCAALHPLDEDL- 52

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 746208302 808 AEFA-VLVRSDLKGLGLGRRLLEKLISYTRDHGLLRLNGITMPNNRGmvtLARKLGF 863
Cdd:COG1246   53 AELRsLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFLLTTSAAIH---FYEKLGF 106
SucC COG0045
Succinyl-CoA synthetase, beta subunit [Energy production and conversion]; Succinyl-CoA ...
 484-693 1.24e-03

Succinyl-CoA synthetase, beta subunit [Energy production and conversion]; Succinyl-CoA synthetase, beta subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 439815 [Multi-domain]  Cd Length: 388  Bit Score: 41.96  E-value: 1.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 484 HEVQ--PILGSYGMQTLPTWIASDSAEAVHIAEQIGY-PVALKlrspdiphksdVQ----------GVMLyLRTATEVQQ 550
Cdd:COG0045    4 HEYQakELLAKYGVPVPRGIVATTPEEAVAAAEELGGpPVVVK-----------AQvhaggrgkagGVKL-AKSPEEARE 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 551 AADAIFDRvKMAWPQA-----RIHGLLVQSMANraGAQELRVVVEHDPVFG-PLIML-GEGGVEW------RPEEQAVVA 617
Cdd:COG0045   72 AAEEILGM-TLVTHQTgpkgkPVNKVLVEEGVD--IAKELYLSILLDRATRrPVIMAsTEGGMDIeevaeeTPEKIIKVP 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302 618 LPPLnMNLARYliiQAiksKKIRGRSALRPLDIAGLSQFLVQVSNLIVDC-AEIqrLDIHPL-LASGNEFTALD--VTLD 693
Cdd:COG0045  149 IDPL-VGLQPY---QA---RELAFALGLPGKQVKQFAKILKKLYRAFVEKdASL--VEINPLvVTKDGRLVALDakVNFD 219
SucD COG0074
Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA ...
 67-207 1.67e-03

Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA synthetase, alpha subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 439844 [Multi-domain]  Cd Length: 288  Bit Score: 41.20  E-value: 1.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  67 PFVPDlAVLctnakrnpELLESlgkkGCKTCIILSS--PPEQKAELLACASRYQMRILGPNSLGLLAPWQgLNASFSPVP 144
Cdd:COG0074   75 PFAAD-AIL--------EAIDA----GIKLIVCITEgiPVLDMVRVKRYAKAKGTRLIGPNCPGIITPGE-CKLGIMPGH 140

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 746208302 145 I-RKGKLAFISQSAAVSNTILDWAQQREMGFSYFIALG-DSL-DIDVDELLDFLARDGKTSAILLY 207
Cdd:COG0074  141 IfKPGRVGIVSRSGTLTYEAVWQLTQAGLGQSTCVGIGgDPIiGTSFIDVLELFEEDPETEAIVMI 206
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
792-863 4.48e-03

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 37.20  E-value: 4.48e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 746208302 792 EILGVTRAISDPDNVDAEFAVLVRSDLKGLGLGRRLLEKLISYTRDHGLLRLNGITMPNNRGMVTLARKLGF 863
Cdd:COG3393    1 ELVAMAGVRAESPGVAEISGVYTHPEYRGRGLASALVAALAREALARGARTPFLYVDADNPAARRLYERLGF 72
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 776-863 6.79e-03

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 36.66  E-value: 6.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746208302  776 DREMAFVAVRrsdkGDEILGVTRAISDPDNVD-AEFAVLVRSDLKGLGLGRRLLEKLISYTRDHGLLRLNGITMPNNRGm 854
Cdd:pfam13508   1 PGGRFFVAED----DGKIVGFAALLPLDDEGAlAELRLAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLELETTNRAAA- 75


                  ....*....
gi 746208302  855 vtLARKLGF 863
Cdd:pfam13508  76 --FYEKLGF 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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