|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
9-792 |
0e+00 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 1624.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 9 RNVLWYNQLGMHDVERVGGKNASLGEMITNLSELGVAVPNGFATTAQAFNDFLNQSGINQRIYELLDRTDIDDLSQLASA 88
Cdd:PRK06464 5 KYVLWFEELGMEDVPLVGGKNASLGEMISNLSGAGVPVPPGFATTAEAYRYFLEQTGLNEKIYELLDGLDVDDVDALAKA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 89 GTQIRQWIIDTPFQPELEKAISDAYQQLADGEKDASFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVAVKHVFASL 168
Cdd:PRK06464 85 GAQIRQLIIDTPFPPDLEQEIREAYAKLSAGYGEASVAVRSSATAEDLPDASFAGQQETFLNVRGIDDVLEAVKECFASL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 169 FNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASAGVMFTIDTESGFDQVVFITSAYGLGEMVVQGAVNPDEFYVHKPT 248
Cdd:PRK06464 165 FTDRAISYRVHQGFDHFKVALSAGVQKMVRSDLAASGVMFTLDTESGFRDVVFITASWGLGEMVVQGAVNPDEFYVHKPT 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 249 LQNNKPAIVRRNMGSKKIRMVYAASQEHGkqVRIEDVPAEQTTRFSLTDDEVQALARQALLIEKHYGRPMDIEWAKDGHT 328
Cdd:PRK06464 245 LKAGKPAIVRRTLGSKKIKMVYDDGGEHG--VKTVDVPEEERNRFSLTDEEVLELAKQAVIIEKHYGRPMDIEWAKDGDD 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 329 GKLYIVQARPETVRS--NGQVMERYHLPASGTVLVEGRAIGHRIGAGEVKVIQDISEMHLINAGDVLVTDMTDPDWEPIM 406
Cdd:PRK06464 323 GKLYIVQARPETVKSrkEANVLERYKLKGQGKVLVEGRAIGPGIGSGKVRVILDISEMDKVQPGDVLVTDMTDPDWEPVM 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 407 KKAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERLRKGQKVTVSCAEGDTGYVYQDLLDFSVKSSQIDEMPALPLK 486
Cdd:PRK06464 403 KRASAIVTNRGGRTCHAAIIARELGIPAVVGTGNATEVLKDGQEVTVSCAEGDTGYVYEGLLEFEVEEVSLEEMPETPTK 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 487 IMMNVGNPDRAFDFACLPNDGVGLARLEFIINRMIGVHPRALLEFDQQAPEVQREIKTLMQGFDDPVEFYVGRLTEGIAT 566
Cdd:PRK06464 483 IMMNVGNPERAFDFAALPNDGVGLARLEFIINNMIGVHPLALLEFDQQDADLKAEIEELTAGYASPEEFYVDKLAEGIAT 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 567 LAAAFSPKRVIVRLSDFKSNEYANLVGGERYEPEEENPMLGFRGAGRYVSPDFKACFALECEAVKRVRNVMGLKNVEIMI 646
Cdd:PRK06464 563 VAAAFYPKPVIVRLSDFKSNEYANLIGGERYEPEEENPMLGFRGASRYLSESFREAFALECEAIKRVREEMGLTNVEVMI 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 647 PFVRTVAQAEAVVAELANQGLRRGEDGLKIIMMCEIPSNALLADEFLQHFDGFSIGSNDMTQLALGLDRDSGVVSSLFDE 726
Cdd:PRK06464 643 PFVRTVEEAEKVIELLAENGLKRGENGLKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGLVAHLFDE 722
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 746227567 727 RNDAVKALLSMAIKAAKKQGKYVGICGQGPSDHEDFALWLMEQGIDSLSLNPDTVVQTWLNLAEHK 792
Cdd:PRK06464 723 RNPAVKKLISMAIKAAKKAGKYVGICGQAPSDHPDFAEWLVEEGIDSISLNPDAVVDTWLAVAEVE 788
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
11-790 |
0e+00 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 1332.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 11 VLWYNQLGMHDVERVGGKNASLGEMITNLSELGVAVPNGFATTAQAFNDFLNQSGINQRIYELLDRTDIDDLSQLASAGT 90
Cdd:TIGR01418 2 ILWLEEVRKDDVPLVGGKNASLGEMIQNLSPAGVPVPPGFVVTAEAYRYFLEENGIAQKIRDLLEELDVEDVDALAAASA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 91 QIRQWIIDTPFQPELEKAISDAYQQLAD--GEKDASFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVAVKHVFASL 168
Cdd:TIGR01418 82 EIRELILNTPFPPDLEEAIREAYDKLSEdyGKEEADVAVRSSATAEDLPDASFAGQQETYLNVTGEEEVLEHVKKCWASL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 169 FNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASAGVMFTIDTESGFDQVVFITSAYGLGEMVVQGAVNPDEFYVHKPT 248
Cdd:TIGR01418 162 FTDRAISYRVSQGFDHEKVAIAVGVQKMVRSDLGSSGVMFTIDTETGFKDAVFIESAWGLGEAVVGGAVTPDEYVVFKPT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 249 LQNNKPAIVRRNMGSKKIRMVYAASQEhGKQVRIEDVPAEQTTRFSLTDDEVQALARQALLIEKHYGRPMDIEWAKDGHT 328
Cdd:TIGR01418 242 LEQGKKAILERTLGSKKIKMVYDPDGG-GVETKIVEVPEEERDAFSLSDEEILELAKLAVLIEKHYGRPMDIEWAKDGFD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 329 GKLYIVQARPETVRSN---GQVMERYHLPASGTVLVEGRAIGHRIGAGEVKVIQDISEMHLINAGDVLVTDMTDPDWEPI 405
Cdd:TIGR01418 321 GEIFIVQARPETVQSRkkkENVEERYELKGKGKVLVTGRAAGPGIASGKVKVIFDLKEMDKFEEGDILVTDMTDPDWEPA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 406 MKKAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERLRKGQKVTVSCAEGDTGYVYQDLLDFSVKSSQIDEMPALPL 485
Cdd:TIGR01418 401 MKRASAIVTNEGGMTCHAAIVARELGIPAVVGTGDATKTLKDGMEVTVDCAEGDTGYVYAGKLEHEVKEVELSNMPVTAT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 486 KIMMNVGNPDRAFDFACLPNDGVGLARLEFIINRMIGVHPRALLEFDQQAPEVQREIKTLMQGfdDPVEFYVGRLTEGIA 565
Cdd:TIGR01418 481 KIYMNVGNPEVAFRFAALPNDGVGLARIEFIILNWIGKHPLALIDDDDLESVEKNEIEELMAG--NPRDFFVDKLAEGIA 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 566 TLAAAFSPKRVIVRLSDFKSNEYANLVGGERYEPEEENPMLGFRGAGRYVSPDFKACFALECEAVKRVRNVMGLKNVEIM 645
Cdd:TIGR01418 559 KVAAAFYPKPVIVRTSDFKSNEYRNLIGGEEYEPDEENPMLGWRGASRYYSESYEEAFRLECRAIKRVREEMGLTNVEVM 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 646 IPFVRTVAQAEAVVAELANQGLRRGEDGLKIIMMCEIPSNALLADEFLQHFDGFSIGSNDMTQLALGLDRDSGVVSSLFD 725
Cdd:TIGR01418 639 IPFVRTPEEGKRALEIMAEEGLRRGKNGLEVYVMCEVPSNALLADEFAKEFDGFSIGSNDLTQLTLGVDRDSGLVAHLFD 718
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 746227567 726 ERNDAVKALLSMAIKAAKKQGKYVGICGQGPSDHEDFALWLMEQGIDSLSLNPDTVVQTWLNLAE 790
Cdd:TIGR01418 719 ERNPAVLRLIEMAIKAAKEHGKKVGICGQAPSDYPEVVEFLVEEGIDSISLNPDAVLRTRLQVAE 783
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
9-463 |
0e+00 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 658.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 9 RNVLWYNQLGMHDVERVGGKNASLGEMITnlseLGVAVPNGFATTAQAFNDFLNQSGINQRIYELLDRTDIDDLSQLASA 88
Cdd:COG0574 3 KYVYWFAEGGADDVDLVGGKGANLGEMTR----LGLPVPPGFTITTEAYRRFLEENGLEEEIRELLADLDVDDVDALAEA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 89 GTQIRQWIIDTPFQPELEKAISDAYQQLADGE-KDASFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVAVKHVFAS 167
Cdd:COG0574 79 SAEIRELILEAPLPEELEEEILAAYAKLEEKFgEDLLVAVRSSATAEDLPDASFAGQMDTVLNVNGNEQLLEAIKAVFAS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 168 LFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASAGVMFTIDTESGFDQVVFITSAYGLGEMVVQGAVNPDEFYVHKP 247
Cdd:COG0574 159 LFTDRAIAYRRHNGIDHDDVGTAVNVQAMVFGNMSASGVMFTRDPSTGEKDVVYIEALNGLGEDVVAGIVTPDPYYVDKP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 248 TlqnnkpaIVRRNMGSKKIRMVYAASqehgkqVRIEDVPAEQTTRFSLTDDEVQALARQALLIEKHYGRPMDIEWAKDgh 327
Cdd:COG0574 239 T-------ILERTLGSKAIKMVYDGG------TVEVPVPPEERNRPSLTDEEYLELARIALRLEKHYGDPQDIEWAID-- 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 328 TGKLYIVQARPETVRSN------------GQVMERYHL------PASGTVLVEGRAIGHRIGAGEVKVIQDISEMHLINA 389
Cdd:COG0574 304 DGKLYILQTRPITVLEGlitkeallrvdpAQLDQLLHPrfdpkaKEEGEVLAKGLPASPGAASGKVVFIADEAELARFQE 383
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 746227567 390 GDVLVTDMTDPDWEPIMKKAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERLRKGQKVTVscaEGDTGYV 463
Cdd:COG0574 384 GVILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATRVLKDGDEITV---DGTTGEV 454
|
|
| PPDK_N |
pfam01326 |
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible ... |
22-353 |
2.17e-164 |
|
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Pssm-ID: 426201 [Multi-domain] Cd Length: 326 Bit Score: 478.62 E-value: 2.17e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 22 VERVGGKNASLGEMitnLSELGVAVPNGFATTAQAFNDFLNQSGINQRIYELLDRTDIDDLSQLASAGTQIRQWIIDTPF 101
Cdd:pfam01326 1 VNLVGGKGANLGEM---LNDAGIPVPPGFAITADAYREFLEENGLREKIDELLKDLDVDDVDELREASKEIRQLILSAPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 102 QPELEKAISDAYQQLAD--GEKDASFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVAVKHVFASLFNDRAISYRVH 179
Cdd:pfam01326 78 PEELEEAIREAYEELGKkfGDEPLPVAVRSSATAEDLPDASFAGQQDTYLNVGGNDEVLEAIKAVFASLFNDRAIAYRRE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 180 QGYDHRGVALSAGVQRMVRSDlaSAGVMFTIDTESGFDQVVFITSAYGLGEMVVQGAVNPDEFYVHKPTLQnnkpaIVRR 259
Cdd:pfam01326 158 KGIDHEDVALAVGVQRMVRSD--ASGVMFSRDPETGFRDEVLINASWGLGEAVVQGRVTPDEFYVFKPTLE-----ILRR 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 260 NMGSKKIRMVYaasQEHGKQVRIEDVPAEQTTRFSLTDDEVQALARQALLIEKHYGRPMDIEWAKDGHTGKLYIVQARPE 339
Cdd:pfam01326 231 TIGEKEIKMVY---DEGGEGTKEVEVPEEKRERFSLSDEEVLELARIAKKIEKHYGTPMDIEWAIDGRDGKLYILQARPE 307
|
330
....*....|....*..
gi 746227567 340 TVRS---NGQVMERYHL 353
Cdd:pfam01326 308 TVWSeamEKIAAEILEE 324
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
9-792 |
0e+00 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 1624.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 9 RNVLWYNQLGMHDVERVGGKNASLGEMITNLSELGVAVPNGFATTAQAFNDFLNQSGINQRIYELLDRTDIDDLSQLASA 88
Cdd:PRK06464 5 KYVLWFEELGMEDVPLVGGKNASLGEMISNLSGAGVPVPPGFATTAEAYRYFLEQTGLNEKIYELLDGLDVDDVDALAKA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 89 GTQIRQWIIDTPFQPELEKAISDAYQQLADGEKDASFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVAVKHVFASL 168
Cdd:PRK06464 85 GAQIRQLIIDTPFPPDLEQEIREAYAKLSAGYGEASVAVRSSATAEDLPDASFAGQQETFLNVRGIDDVLEAVKECFASL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 169 FNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASAGVMFTIDTESGFDQVVFITSAYGLGEMVVQGAVNPDEFYVHKPT 248
Cdd:PRK06464 165 FTDRAISYRVHQGFDHFKVALSAGVQKMVRSDLAASGVMFTLDTESGFRDVVFITASWGLGEMVVQGAVNPDEFYVHKPT 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 249 LQNNKPAIVRRNMGSKKIRMVYAASQEHGkqVRIEDVPAEQTTRFSLTDDEVQALARQALLIEKHYGRPMDIEWAKDGHT 328
Cdd:PRK06464 245 LKAGKPAIVRRTLGSKKIKMVYDDGGEHG--VKTVDVPEEERNRFSLTDEEVLELAKQAVIIEKHYGRPMDIEWAKDGDD 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 329 GKLYIVQARPETVRS--NGQVMERYHLPASGTVLVEGRAIGHRIGAGEVKVIQDISEMHLINAGDVLVTDMTDPDWEPIM 406
Cdd:PRK06464 323 GKLYIVQARPETVKSrkEANVLERYKLKGQGKVLVEGRAIGPGIGSGKVRVILDISEMDKVQPGDVLVTDMTDPDWEPVM 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 407 KKAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERLRKGQKVTVSCAEGDTGYVYQDLLDFSVKSSQIDEMPALPLK 486
Cdd:PRK06464 403 KRASAIVTNRGGRTCHAAIIARELGIPAVVGTGNATEVLKDGQEVTVSCAEGDTGYVYEGLLEFEVEEVSLEEMPETPTK 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 487 IMMNVGNPDRAFDFACLPNDGVGLARLEFIINRMIGVHPRALLEFDQQAPEVQREIKTLMQGFDDPVEFYVGRLTEGIAT 566
Cdd:PRK06464 483 IMMNVGNPERAFDFAALPNDGVGLARLEFIINNMIGVHPLALLEFDQQDADLKAEIEELTAGYASPEEFYVDKLAEGIAT 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 567 LAAAFSPKRVIVRLSDFKSNEYANLVGGERYEPEEENPMLGFRGAGRYVSPDFKACFALECEAVKRVRNVMGLKNVEIMI 646
Cdd:PRK06464 563 VAAAFYPKPVIVRLSDFKSNEYANLIGGERYEPEEENPMLGFRGASRYLSESFREAFALECEAIKRVREEMGLTNVEVMI 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 647 PFVRTVAQAEAVVAELANQGLRRGEDGLKIIMMCEIPSNALLADEFLQHFDGFSIGSNDMTQLALGLDRDSGVVSSLFDE 726
Cdd:PRK06464 643 PFVRTVEEAEKVIELLAENGLKRGENGLKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGLVAHLFDE 722
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 746227567 727 RNDAVKALLSMAIKAAKKQGKYVGICGQGPSDHEDFALWLMEQGIDSLSLNPDTVVQTWLNLAEHK 792
Cdd:PRK06464 723 RNPAVKKLISMAIKAAKKAGKYVGICGQAPSDHPDFAEWLVEEGIDSISLNPDAVVDTWLAVAEVE 788
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
11-790 |
0e+00 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 1332.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 11 VLWYNQLGMHDVERVGGKNASLGEMITNLSELGVAVPNGFATTAQAFNDFLNQSGINQRIYELLDRTDIDDLSQLASAGT 90
Cdd:TIGR01418 2 ILWLEEVRKDDVPLVGGKNASLGEMIQNLSPAGVPVPPGFVVTAEAYRYFLEENGIAQKIRDLLEELDVEDVDALAAASA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 91 QIRQWIIDTPFQPELEKAISDAYQQLAD--GEKDASFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVAVKHVFASL 168
Cdd:TIGR01418 82 EIRELILNTPFPPDLEEAIREAYDKLSEdyGKEEADVAVRSSATAEDLPDASFAGQQETYLNVTGEEEVLEHVKKCWASL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 169 FNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASAGVMFTIDTESGFDQVVFITSAYGLGEMVVQGAVNPDEFYVHKPT 248
Cdd:TIGR01418 162 FTDRAISYRVSQGFDHEKVAIAVGVQKMVRSDLGSSGVMFTIDTETGFKDAVFIESAWGLGEAVVGGAVTPDEYVVFKPT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 249 LQNNKPAIVRRNMGSKKIRMVYAASQEhGKQVRIEDVPAEQTTRFSLTDDEVQALARQALLIEKHYGRPMDIEWAKDGHT 328
Cdd:TIGR01418 242 LEQGKKAILERTLGSKKIKMVYDPDGG-GVETKIVEVPEEERDAFSLSDEEILELAKLAVLIEKHYGRPMDIEWAKDGFD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 329 GKLYIVQARPETVRSN---GQVMERYHLPASGTVLVEGRAIGHRIGAGEVKVIQDISEMHLINAGDVLVTDMTDPDWEPI 405
Cdd:TIGR01418 321 GEIFIVQARPETVQSRkkkENVEERYELKGKGKVLVTGRAAGPGIASGKVKVIFDLKEMDKFEEGDILVTDMTDPDWEPA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 406 MKKAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERLRKGQKVTVSCAEGDTGYVYQDLLDFSVKSSQIDEMPALPL 485
Cdd:TIGR01418 401 MKRASAIVTNEGGMTCHAAIVARELGIPAVVGTGDATKTLKDGMEVTVDCAEGDTGYVYAGKLEHEVKEVELSNMPVTAT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 486 KIMMNVGNPDRAFDFACLPNDGVGLARLEFIINRMIGVHPRALLEFDQQAPEVQREIKTLMQGfdDPVEFYVGRLTEGIA 565
Cdd:TIGR01418 481 KIYMNVGNPEVAFRFAALPNDGVGLARIEFIILNWIGKHPLALIDDDDLESVEKNEIEELMAG--NPRDFFVDKLAEGIA 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 566 TLAAAFSPKRVIVRLSDFKSNEYANLVGGERYEPEEENPMLGFRGAGRYVSPDFKACFALECEAVKRVRNVMGLKNVEIM 645
Cdd:TIGR01418 559 KVAAAFYPKPVIVRTSDFKSNEYRNLIGGEEYEPDEENPMLGWRGASRYYSESYEEAFRLECRAIKRVREEMGLTNVEVM 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 646 IPFVRTVAQAEAVVAELANQGLRRGEDGLKIIMMCEIPSNALLADEFLQHFDGFSIGSNDMTQLALGLDRDSGVVSSLFD 725
Cdd:TIGR01418 639 IPFVRTPEEGKRALEIMAEEGLRRGKNGLEVYVMCEVPSNALLADEFAKEFDGFSIGSNDLTQLTLGVDRDSGLVAHLFD 718
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 746227567 726 ERNDAVKALLSMAIKAAKKQGKYVGICGQGPSDHEDFALWLMEQGIDSLSLNPDTVVQTWLNLAE 790
Cdd:TIGR01418 719 ERNPAVLRLIEMAIKAAKEHGKKVGICGQAPSDYPEVVEFLVEEGIDSISLNPDAVLRTRLQVAE 783
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
9-463 |
0e+00 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 658.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 9 RNVLWYNQLGMHDVERVGGKNASLGEMITnlseLGVAVPNGFATTAQAFNDFLNQSGINQRIYELLDRTDIDDLSQLASA 88
Cdd:COG0574 3 KYVYWFAEGGADDVDLVGGKGANLGEMTR----LGLPVPPGFTITTEAYRRFLEENGLEEEIRELLADLDVDDVDALAEA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 89 GTQIRQWIIDTPFQPELEKAISDAYQQLADGE-KDASFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVAVKHVFAS 167
Cdd:COG0574 79 SAEIRELILEAPLPEELEEEILAAYAKLEEKFgEDLLVAVRSSATAEDLPDASFAGQMDTVLNVNGNEQLLEAIKAVFAS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 168 LFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASAGVMFTIDTESGFDQVVFITSAYGLGEMVVQGAVNPDEFYVHKP 247
Cdd:COG0574 159 LFTDRAIAYRRHNGIDHDDVGTAVNVQAMVFGNMSASGVMFTRDPSTGEKDVVYIEALNGLGEDVVAGIVTPDPYYVDKP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 248 TlqnnkpaIVRRNMGSKKIRMVYAASqehgkqVRIEDVPAEQTTRFSLTDDEVQALARQALLIEKHYGRPMDIEWAKDgh 327
Cdd:COG0574 239 T-------ILERTLGSKAIKMVYDGG------TVEVPVPPEERNRPSLTDEEYLELARIALRLEKHYGDPQDIEWAID-- 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 328 TGKLYIVQARPETVRSN------------GQVMERYHL------PASGTVLVEGRAIGHRIGAGEVKVIQDISEMHLINA 389
Cdd:COG0574 304 DGKLYILQTRPITVLEGlitkeallrvdpAQLDQLLHPrfdpkaKEEGEVLAKGLPASPGAASGKVVFIADEAELARFQE 383
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 746227567 390 GDVLVTDMTDPDWEPIMKKAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERLRKGQKVTVscaEGDTGYV 463
Cdd:COG0574 384 GVILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATRVLKDGDEITV---DGTTGEV 454
|
|
| PPDK_N |
pfam01326 |
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible ... |
22-353 |
2.17e-164 |
|
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Pssm-ID: 426201 [Multi-domain] Cd Length: 326 Bit Score: 478.62 E-value: 2.17e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 22 VERVGGKNASLGEMitnLSELGVAVPNGFATTAQAFNDFLNQSGINQRIYELLDRTDIDDLSQLASAGTQIRQWIIDTPF 101
Cdd:pfam01326 1 VNLVGGKGANLGEM---LNDAGIPVPPGFAITADAYREFLEENGLREKIDELLKDLDVDDVDELREASKEIRQLILSAPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 102 QPELEKAISDAYQQLAD--GEKDASFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVAVKHVFASLFNDRAISYRVH 179
Cdd:pfam01326 78 PEELEEAIREAYEELGKkfGDEPLPVAVRSSATAEDLPDASFAGQQDTYLNVGGNDEVLEAIKAVFASLFNDRAIAYRRE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 180 QGYDHRGVALSAGVQRMVRSDlaSAGVMFTIDTESGFDQVVFITSAYGLGEMVVQGAVNPDEFYVHKPTLQnnkpaIVRR 259
Cdd:pfam01326 158 KGIDHEDVALAVGVQRMVRSD--ASGVMFSRDPETGFRDEVLINASWGLGEAVVQGRVTPDEFYVFKPTLE-----ILRR 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 260 NMGSKKIRMVYaasQEHGKQVRIEDVPAEQTTRFSLTDDEVQALARQALLIEKHYGRPMDIEWAKDGHTGKLYIVQARPE 339
Cdd:pfam01326 231 TIGEKEIKMVY---DEGGEGTKEVEVPEEKRERFSLSDEEVLELARIAKKIEKHYGTPMDIEWAIDGRDGKLYILQARPE 307
|
330
....*....|....*..
gi 746227567 340 TVRS---NGQVMERYHL 353
Cdd:pfam01326 308 TVWSeamEKIAAEILEE 324
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
17-340 |
8.06e-99 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 326.08 E-value: 8.06e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 17 LGMHDVER-----VGGKNASLGEMitnlSELGVAVPNGFATTAQAFNDFLNQSGINQRIYELLDRTDIDDLSQLASAGTQ 91
Cdd:PRK06241 6 LDFQEIDKtqlplVGGKGANLGEL----SRAGIPVPEGFCVTTEAYKKFLEQNEEFDALLDQLSALKLEDREQIGEISAK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 92 IRQWIIDTPFQPELEKAISDAYQQLadGEKDAsFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVAVKHVFASLFND 171
Cdd:PRK06241 82 IREVIEAIEIPEDIVEAIAAALSKF--GEDHA-YAVRSSATAEDLPTASFAGQQDTYLNVIGKDAILQHIRKCWASLFTE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 172 RAISYRVHQGYDHRGVALSAGVQRMVRSDLasAGVMFTIDTESGFDQVVFITSAYGLGEMVVQGAVNPDEFYVHKPTlqn 251
Cdd:PRK06241 159 RAVIYRIQNGFDHRKVYMSVVVQKMVFPEA--SGIMFTADPVTGNRKVLSIDASFGLGEALVSGLVSADTYKVREGK--- 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 252 nkpaIVRRNMGSKKIRMVyaASQEHGKQVRieDVPAEQTTRFSLTDDEVQALARQALLIEKHYGRPMDIEWAKDGhtGKL 331
Cdd:PRK06241 234 ----IIDKTIATKKLAIY--ALKEGGTETK--EIEPEQQKSQTLTDEQILELARLGRKIEAHFGCPQDIEWCLAD--GTF 303
|
....*....
gi 746227567 332 YIVQARPET 340
Cdd:PRK06241 304 YILQSRPIT 312
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
485-781 |
5.16e-58 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 199.46 E-value: 5.16e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 485 LKIMMNVGNPDRAFDFACLPNDGVGLARLEFIInrmigvhpralleFDQQAPEVQREiktlmqgfddpvefyvgrLTEGI 564
Cdd:pfam02896 20 IKVAANIGTPDDAEAALANGAEGIGLYRTEFLF-------------MDRDELPTEDE------------------QFEAY 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 565 ATLAAAFSPKRVIVRLSDFKSNEYanLVGGEryEPEEENPMLGFRGAGRYVSPdfKACFALECEAVKRVRNVMglkNVEI 644
Cdd:pfam02896 69 KGVLEAMNGRPVTVRTLDIGGDKE--LPYLE--EPEEMNPFLGWRGIRIGLDR--PELFRTQLRAILRASAFG---NLRI 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 645 MIPFVRTVA---QAEAVVAELANQGLRRGE--DGLKIIMMCEIPSNALLADEFLQHFDGFSIGSNDMTQLALGLDRDSGV 719
Cdd:pfam02896 140 MFPMVASVEelrEAKAIIEEVKEELDAEVGfdKDIKVGIMIEVPSAALLADQLAKEVDFFSIGTNDLTQYTLAVDRDNER 219
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 746227567 720 VSSLFDERNDAVKALLSMAIKAAKKQGKYVGICGQGPSDhEDFALWLMEQGIDSLSLNPDTV 781
Cdd:pfam02896 220 VAYLYDPLHPAVLRLIKEVIRAAHRHGKWVGICGEMAGD-PSAVPLLVGLGLDEFSMSPDSV 280
|
|
| PtsA |
COG1080 |
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ... |
407-778 |
4.02e-50 |
|
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];
Pssm-ID: 440698 [Multi-domain] Cd Length: 571 Bit Score: 185.28 E-value: 4.02e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 407 KKAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERLRKGQKVTVscaEGDTGYVY-----QDLLDFSVKSSQIDEM- 480
Cdd:COG1080 173 SRVAGFVTDLGGRTSHTAILARSLGIPAVVGLGDALLLVKDGDLVIV---DGDAGVVIvnpdeETLAEYRERQAEYAAEr 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 481 ---------PAL-----PLKIMMNVGNPD---RAFDFAClpnDGVGLARLEFI-INRmigvhprallefdQQAP--EVQR 540
Cdd:COG1080 250 aelarlrdlPAVtldgvRVELAANIGLPEdaaAALENGA---EGVGLFRTEFLfMDR-------------DDLPteEEQF 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 541 EIktlmqgfddpvefYvgrltegiATLAAAFSPKRVIVRLSDfksneyanlVGGE---RY--EPEEENPMLGFRGAgRYv 615
Cdd:COG1080 314 EA-------------Y--------RAVAEAMGGRPVTIRTLD---------IGGDkplPYlpLPKEENPFLGLRAI-RL- 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 616 SPDFKACFALECEAVKRVrNVMGlkNVEIMIPFVRTV-------AQAEAVVAELANQGLRRGEDgLKIIMMCEIPSNALL 688
Cdd:COG1080 362 CLDRPELFRTQLRAILRA-SAHG--NLRIMFPMISSVeelrqakALLEEAKAELRAEGIPFDED-IPVGIMIEVPAAALI 437
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 689 ADEFLQHFDGFSIGSNDMTQLALGLDRDSGVVSSLFDERNDAVKALLSMAIKAAKKQGKYVGICGQGPSDhEDFALWLME 768
Cdd:COG1080 438 ADQLAKEVDFFSIGTNDLIQYTLAVDRGNEKVAYLYDPLHPAVLRLIKMVIDAAHKAGKPVGVCGEMAGD-PLATPLLLG 516
|
410
....*....|
gi 746227567 769 QGIDSLSLNP 778
Cdd:COG1080 517 LGLDELSMSP 526
|
|
| PEP-utilizers |
pfam00391 |
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain ... |
387-458 |
2.71e-32 |
|
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.
Pssm-ID: 459796 [Multi-domain] Cd Length: 73 Bit Score: 119.44 E-value: 2.71e-32
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 746227567 387 INAGDVLVTDMTDPDWEPIMKKAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERLRKGQKVTVSCAEG 458
Cdd:pfam00391 2 LPEGVILVAPDTTPSDTAGLDKAAGIVTERGGMTSHAAIVARELGIPAVVGVGDATILLKEGDLVTVDGSTG 73
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
357-465 |
3.75e-31 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 124.63 E-value: 3.75e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 357 GTVLVEGRAIGHRIGAGEVKVIQDISE-MHLINAGDVLVTDMTDPDWEPIMKKAAAIVTNRGGRTCHAAIIARELGIPAV 435
Cdd:COG3848 209 GDVLAKGQGIGRGSVTGKAVVARSAEEaLEKFEEGDILVVPSTDAEFVPAIEKAAGIITEEGGLTSHAAIVGLELGIPVI 288
|
90 100 110
....*....|....*....|....*....|
gi 746227567 436 VGCGDATERLRKGQKVTVscaEGDTGYVYQ 465
Cdd:COG3848 289 VGAEGATEILKDGQVVTV---DAERGVVYR 315
|
|
| PRK11177 |
PRK11177 |
phosphoenolpyruvate-protein phosphotransferase PtsI; |
364-776 |
1.56e-28 |
|
phosphoenolpyruvate-protein phosphotransferase PtsI;
Pssm-ID: 183017 [Multi-domain] Cd Length: 575 Bit Score: 121.27 E-value: 1.56e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 364 RAIGHRIgagevkvIQDISEMHLINAGD-----VLV-TDMTDPDWEPI-MKKAAAIVTNRGGRTCHAAIIARELGIPAVV 436
Cdd:PRK11177 131 RDIGKRL-------LKNILGLKIIDLSAiqeevILVaADLTPSETAQLnLKKVLGFITDIGGRTSHTSIMARSLELPAIV 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 437 GCGDATERLRKG---------QKVTV--SCAEGDTGYVYQDLLDFSVKS-SQIDEMPALPL-----KIMMNVGNPdRAFD 499
Cdd:PRK11177 204 GTGNITKQVKNGdylildavnNQIYVnpTNEVIEELKAVQEQYASEKAElAKLKDLPAITLdghqvEVCANIGTV-RDVE 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 500 FAcLPN--DGVGLARLEFI-INRmigvhpRALLEFDQQapevqreiktlMQGFDDPVEfyvgrltegiatlaaAFSPKRV 576
Cdd:PRK11177 283 GA-ERNgaEGVGLYRTEFLfMDR------DALPTEEEQ-----------FQAYKAVAE---------------AMGSQAV 329
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 577 IVRLSDF---KSNEYANLvggeryePEEENPMLGFRgAGRyVSPDFKACFALECEAVKRVRNVMGLKnveIMIPFVRTV- 652
Cdd:PRK11177 330 IVRTMDIggdKELPYMNL-------PKEENPFLGWR-AIR-IAMDRKEILHDQLRAILRASAFGKLR---IMFPMIISVe 397
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 653 ------AQAEAVVAELANQGLRRGEDgLKIIMMCEIPSNALLADEFLQHFDGFSIGSNDMTQLALGLDRDSGVVSSLFDE 726
Cdd:PRK11177 398 evrelkAEIEILKQELRDEGKAFDES-IEIGVMVETPAAAVIARHLAKEVDFFSIGTNDLTQYTLAVDRGNELISHLYNP 476
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 746227567 727 RNDAVKALLSMAIKAAKKQGKYVGICGQGPSDhEDFALWLMEQGIDSLSL 776
Cdd:PRK11177 477 MSPSVLNLIKQVIDASHAEGKWTGMCGELAGD-ERATLLLLGMGLDEFSM 525
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
353-463 |
2.44e-23 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 106.13 E-value: 2.44e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 353 LPASGTVlVEGRAighrigagevKVIQDIsEMHLINAGDVLVTDMTDPDWEPIMKKAAAIVTNRGGRTCHAAIIARELGI 432
Cdd:PRK06241 771 LPVSSGV-VEGRA----------RVILNP-EDADLEKGDILVTAFTDPGWTPLFVSIKGLVTEVGGLMTHGAVIAREYGI 838
|
90 100 110
....*....|....*....|....*....|.
gi 746227567 433 PAVVGCGDATERLRKGQKVTVscaEGDTGYV 463
Cdd:PRK06241 839 PAVVGVENATKLIKDGQRIRV---DGTEGYV 866
|
|
| PRK08296 |
PRK08296 |
hypothetical protein; Provisional |
354-463 |
4.84e-23 |
|
hypothetical protein; Provisional
Pssm-ID: 181362 Cd Length: 603 Bit Score: 104.35 E-value: 4.84e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 354 PASGTVlVEGRAighrigagevKVIQDISEMHLINAGDVLVTDMTDPDWEPIMKKAAAIVTNRGGRTCHAAIIARELGIP 433
Cdd:PRK08296 504 AASPGV-VEGPA----------RVIRSADELSEVQEGEILVCPVTSPSWAPIFAKIKATVTDIGGVMSHAAIVCREYGLP 572
|
90 100 110
....*....|....*....|....*....|
gi 746227567 434 AVVGCGDATERLRKGQKVTVscaEGDTGYV 463
Cdd:PRK08296 573 AVVGTGNATKRIKTGQRLRV---DGTKGVV 599
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
357-465 |
2.79e-22 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 101.93 E-value: 2.79e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 357 GTVLVEGRAIGHRIGAGEVKVIQDISEMHLINAGDVLVTDMTDPDWEPIMKKAAAIVTNRGGRTCHAAIIARELGIPAVV 436
Cdd:PRK06354 479 GAVVAKGQGIGRKSVSGKARVAKTAAEVAKVNEGDILVTPSTDADMIPAIEKAAAIITEEGGLTSHAAVVGLRLGIPVIV 558
|
90 100
....*....|....*....|....*....
gi 746227567 437 GCGDATERLRKGQKVTVSCAEGDtgyVYQ 465
Cdd:PRK06354 559 GVKNATSLIKDGQIITVDAARGV---VYS 584
|
|
| PRK05878 |
PRK05878 |
pyruvate phosphate dikinase; Provisional |
160-479 |
1.34e-21 |
|
pyruvate phosphate dikinase; Provisional
Pssm-ID: 235635 [Multi-domain] Cd Length: 530 Bit Score: 99.43 E-value: 1.34e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 160 AVKHVFASLFNDRAISYRVHQGYDHR-GVALSagVQRMV---RSDLASAGVMFTIDTESGFDQVVFITSAYGLGEMVVQG 235
Cdd:PRK05878 165 AIEAVFASWNSPRAVAYRRHHGLDDDgGTAVV--VQAMVfgnLDANSGTGVLFSRNPITGANEPFGEWLPGGQGEDVVSG 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 236 AVNPDefyvHKPTLQNNKPAivrrnmgskkirmVYaasqehgkqvriedvpaeqttrfsltdDEVQALARQallIEKHYG 315
Cdd:PRK05878 243 LVDVA----PITALRDEQPA-------------VY---------------------------DELMAAART---LERLGR 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 316 RPMDIEWAKDghTGKLYIVQAR--------------------------------PETVRSngqvMERYHLP----ASGTV 359
Cdd:PRK05878 276 DVQDIEFTVE--SGKLWLLQTRsakrsaqaavrlalqlhdegliddaealrrvtPTHVET----LLRPSLQpearLAAPL 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 360 LVEGRAIGHRIGAGevKVIQDISE-MHLINAGD--VLVTDMTDPDWEPIMKKAAAIVTNRGGRTCHAAIIARELGIPAVV 436
Cdd:PRK05878 350 LAKGLPACPGVVSG--TAYTDVDEaLDAADRGEpvILVRDHTRPDDVHGMLAAQGIVTEVGGATSHAAVVSRELGRVAVV 427
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 746227567 437 GCGDATERLRKGQKVTVscaEGDTGYVYQDLLDFSVKSSQIDE 479
Cdd:PRK05878 428 GCGAGVAAALAGKEITV---DGYEGEVRQGVLALSAWSESDTP 467
|
|
| PRK11061 |
PRK11061 |
phosphoenolpyruvate--protein phosphotransferase; |
407-781 |
3.74e-19 |
|
phosphoenolpyruvate--protein phosphotransferase;
Pssm-ID: 182937 [Multi-domain] Cd Length: 748 Bit Score: 92.36 E-value: 3.74e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 407 KKAAAIVTNRGGRTCHAAIIARELGIPAVVGcGDATERLRKGQKVTVscaEGDTGYV-----------YQDLLDFSVKSS 475
Cdd:PRK11061 341 DRLAGVVVRDGAANSHAAILVRALGIPTVMG-ADIQPSLLHQRLLIV---DGYRGELlvdpepvllqeYQRLISEEIELS 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 476 QIDE----MPAL-----PLKIMMNVG-NPD--RAFDFAClpnDGVGLARLEfiINRMigvhprallefdqqapevqreik 543
Cdd:PRK11061 417 RLAEddvnLPAQlksgeRIKVMLNAGlSAEheEKLGSRV---DGVGLYRTE--IPFM----------------------- 468
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 544 tLMQGF---DDPVEFYVGRLtegiatlaAAFSPKRVIVRLSDfksneyanlVGGER---YEP-EEENPMLGFRGAgrYVS 616
Cdd:PRK11061 469 -LQSGFpseEEQVAQYQGML--------QMFPDKPVTLRTLD---------IGADKqlpYMPiSEENPCLGWRGI--RIT 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 617 PDFKACFALECEAVkrVRNVMGLKNVEIMIPFV----------RTVAQAEAVVAELANQGLRRGedglKIIMMCEIPSNA 686
Cdd:PRK11061 529 LDQPEIFLIQVRAM--LRANAATGNLSILLPMVtsidevdearRLIDRAGREVEEMLGYEIPKP----RIGIMIEVPSMV 602
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 687 LLADEFLQHFDGFSIGSNDMTQLALGLDRDSGVVSSLFDERNDAVKALLSMAIKAAKKQGKYVGICGQGPSDHEDfALWL 766
Cdd:PRK11061 603 FMLPHLASRVDFISVGTNDLTQYLLAVDRNNTRVASLYDSLHPAMLRALKMIADEAEQHGLPVSLCGEMAGDPMG-ALLL 681
|
410
....*....|....*
gi 746227567 767 MEQGIDSLSLNPDTV 781
Cdd:PRK11061 682 IGLGYRHLSMNGRSV 696
|
|
| PRK05865 |
PRK05865 |
sugar epimerase family protein; |
258-467 |
1.01e-08 |
|
sugar epimerase family protein;
Pssm-ID: 235630 [Multi-domain] Cd Length: 854 Bit Score: 58.90 E-value: 1.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 258 RRNMGSKKIRMVYAASQEHGKQVRIEDVPAEQTTRFSLTDDEVQALarqalliekhygrPMDI-EWAKDGHTGKLYIVQA 336
Cdd:PRK05865 644 RRDRMVRAIWVLRALLREYGRRLTEAGVFDTPDDVFYLLVDEIDAL-------------PADVsGLVARRRAEQRRLAGI 710
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 337 RPETVRSNGQVMERYHLPA-SGTVLVEGRAI-GHRIgAGEVKVI--QDISEMHlinAGDVLVTDMTDPDWEPIMKKAAAI 412
Cdd:PRK05865 711 VPPTVFSGSWEPSPSSAAAlAAGDTLRGVGVcGGRV-RGRVRIVrpETIDDLQ---PGEILVAEVTDVGYTAAFCYAAAV 786
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 746227567 413 VTNRGGRTCHAAIIARELGIPAVVGCGDATERLRKGQKVTVS-----------CAEGDTGYVYQDL 467
Cdd:PRK05865 787 VTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVEVDgatgeihvvelASEDGPALPGSDL 852
|
|
| PRK05849 |
PRK05849 |
hypothetical protein; Provisional |
126-343 |
1.02e-07 |
|
hypothetical protein; Provisional
Pssm-ID: 235623 [Multi-domain] Cd Length: 783 Bit Score: 55.76 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 126 AVRSSATAEDMPDASFAGQQETFLNV--QGIDAVMVAVKHVFASLfndraisyrvhqGYDHRGVALsagVQRMVRsDLAS 203
Cdd:PRK05849 59 IVRSSSRSEDSSSSSNAGAFLSILNVnaDSKDQLLKAIEKVIASY------------GTSKDDEIL---VQPMLE-DIVL 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746227567 204 AGVMFTIDTESGFDQVVfitsayglgemvvqgaVNPDEfyvhkptlqNNKPAIVRRNMGSKKIRMVYAASQEHGKQVRIE 283
Cdd:PRK05849 123 SGVAMSRDPESGAPYYV----------------INYDE---------SGSTDSVTSGSGGSATTVYHYRDALVFKPPRLK 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 746227567 284 dvpaeqttrfsltddEVQALARQallIEKHYGR-PMDIEWAKDGHtGKLYIVQARPETVRS 343
Cdd:PRK05849 178 ---------------KLIELIRE---LEALFGCdFLDIEFAIDEK-EELYILQVRPITVPE 219
|
|
| PRK05849 |
PRK05849 |
hypothetical protein; Provisional |
399-456 |
8.75e-07 |
|
hypothetical protein; Provisional
Pssm-ID: 235623 [Multi-domain] Cd Length: 783 Bit Score: 52.68 E-value: 8.75e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 746227567 399 DP--DW---EPImkkaAAIVTNRGGRTCHAAIIARELGIPAVVGCGD-ATERLRKGQKVTVSCA 456
Cdd:PRK05849 717 DPgyDWlftKGI----AGLITCYGGANSHMAIRAAELGLPAVIGVGEeLFEKWLKAKRILLDCA 776
|
|
| PRK11377 |
PRK11377 |
dihydroxyacetone kinase subunit M; Provisional |
416-458 |
1.26e-04 |
|
dihydroxyacetone kinase subunit M; Provisional
Pssm-ID: 183108 [Multi-domain] Cd Length: 473 Bit Score: 45.51 E-value: 1.26e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 746227567 416 RGGRTC-HAAIIARELGIPAVVGCGDATERLRKGQKVTVSCAEG 458
Cdd:PRK11377 424 SAGSPLsHSAIIARELGIGWICQQGEKLYAIQPEETLTLDVKTQ 467
|
|
| |
