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Conserved domains on  [gi|752544915|ref|WP_041216340|]
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2-octaprenyl-6-methoxyphenyl hydroxylase [Aeromonas hydrophila]

Protein Classification

2-octaprenyl-6-methoxyphenyl hydroxylase( domain architecture ID 10012574)

2-octaprenyl-6-methoxyphenyl hydroxylase acts as an oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone

EC:  1.14.13.-
Gene Ontology:  GO:0016491

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 7-401 5.39e-179

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


:

Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 503.62  E-value: 5.39e-179
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   7 NHVDVAIVGGGMSGAVLALSLAALPGPKpLQILLLEASAPELNAHPGFDARAIALSAGTCEALARHGLWSRFAPHCSPIS 86
Cdd:PRK05732   2 SRMDVIIVGGGMAGATLALALSRLSHGG-LPVALIEAFAPESDAHPGFDARAIALAAGTCQQLARLGVWQALADCATPIT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  87 QIHVSDRGHFGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLCPAQLERVEPLTEGVNLTLAGGERYQTRL 166
Cdd:PRK05732  81 HIHVSDRGHAGFVRLDAEDYGVPALGYVVELHDVGQRLFALLDKAPGVTLHCPARVANVERTQGSVRVTLDDGETLTGRL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 167 LVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGGLSSLVWSVARDEAPALMAL 246
Cdd:PRK05732 161 LVAADGSHSALREALGIDWQQHPYEQVAVIANVTTSEAHQGRAFERFTEHGPLALLPMSDGRCSLVWCHPLEDAEEVLSW 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 247 DDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVGRAL 326
Cdd:PRK05732 241 SDAQFLAELQQAFGWRLGRITHAGKRSAYPLALVTAAQQISHRLALVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQAL 320

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 752544915 327 TAGEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLASRTLGFVAD 401
Cdd:PRK05732 321 ARGEDIGDYAVLQRYQQRRQQDREATIGFTDGLVRLFANRWAPLVVGRNLGLMAMDLLPPARDWLARRTLGWVAR 395
 
Name Accession Description Interval E-value
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 7-401 5.39e-179

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 503.62  E-value: 5.39e-179
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   7 NHVDVAIVGGGMSGAVLALSLAALPGPKpLQILLLEASAPELNAHPGFDARAIALSAGTCEALARHGLWSRFAPHCSPIS 86
Cdd:PRK05732   2 SRMDVIIVGGGMAGATLALALSRLSHGG-LPVALIEAFAPESDAHPGFDARAIALAAGTCQQLARLGVWQALADCATPIT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  87 QIHVSDRGHFGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLCPAQLERVEPLTEGVNLTLAGGERYQTRL 166
Cdd:PRK05732  81 HIHVSDRGHAGFVRLDAEDYGVPALGYVVELHDVGQRLFALLDKAPGVTLHCPARVANVERTQGSVRVTLDDGETLTGRL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 167 LVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGGLSSLVWSVARDEAPALMAL 246
Cdd:PRK05732 161 LVAADGSHSALREALGIDWQQHPYEQVAVIANVTTSEAHQGRAFERFTEHGPLALLPMSDGRCSLVWCHPLEDAEEVLSW 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 247 DDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVGRAL 326
Cdd:PRK05732 241 SDAQFLAELQQAFGWRLGRITHAGKRSAYPLALVTAAQQISHRLALVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQAL 320

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 752544915 327 TAGEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLASRTLGFVAD 401
Cdd:PRK05732 321 ARGEDIGDYAVLQRYQQRRQQDREATIGFTDGLVRLFANRWAPLVVGRNLGLMAMDLLPPARDWLARRTLGWVAR 395
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 10-397 2.97e-149

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 427.89  E-value: 2.97e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   10 DVAIVGGGMSGAVLALSLAALPGpkpLQILLLEASAPElNAHPGFDARAIALSAGTCEALARHGLWSRFAPHCSPISQIH 89
Cdd:TIGR01984   1 DVIIVGGGLVGLSLALALSRLGK---IKIALIEANSPS-AAQPGFDARSLALSYGSKQILEKLGLWPKLAPFATPILDIH 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   90 VSDRGHFGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLCPAQLERVEPLTEGVNLTLAGGERYQTRLLVA 169
Cdd:TIGR01984  77 VSDQGHFGATHLRASEFGLPALGYVVELADLGQALLSRLALLTNIQLYCPARYKEIIRNQDYVRVTLDNGQQLRAKLLIA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  170 ADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGG-LSSLVWSVARDEAPALMALDD 248
Cdd:TIGR01984 157 ADGANSKVRELLSIPTEEHDYNQTALIANIRHEQPHQGCAFERFTPHGPLALLPLKDNyRSSLVWCLPSKQADTIANLPD 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  249 AAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVgraLTA 328
Cdd:TIGR01984 237 AEFLAELQQAFGWRLGKITQVGERKTYPLKLRIAETHVHPRVVLIGNAAQTLHPIAGQGFNLGLRDVETLAEVL---IDA 313

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 752544915  329 GEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLASRTLG 397
Cdd:TIGR01984 314 RIDLGTYALLQEYLRRRQFDQFITIGLTDGLNRLFSNHIPLLRALRNLGLLALENFPPLKKRLARQAMG 382
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 8-389 1.01e-54

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 183.60  E-value: 1.01e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   8 HVDVAIVGGGMSGAVLALSLAAlpgpKPLQILLLEASAPelnahPGFDARAIALSAGTCEALARHGLWSRFAPHCSPISQ 87
Cdd:COG0654    3 RTDVLIVGGGPAGLALALALAR----AGIRVTVVERAPP-----PRPDGRGIALSPRSLELLRRLGLWDRLLARGAPIRG 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  88 IHVSDRGHFGQ-AGLTAAEYGLPAlGQVIELSAAGIALQQAIAACPqIRMLCPAQLERVEPLTEGVNLTLAGGERYQTRL 166
Cdd:COG0654   74 IRVRDGSDGRVlARFDAAETGLPA-GLVVPRADLERALLEAARALG-VELRFGTEVTGLEQDADGVTVTLADGRTLRADL 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 167 LVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTaedpagraferftqggplallpmqgglsslvwsvardeapalmal 246
Cdd:COG0654  152 VVGADGARSAVRRLLGIGFTGRDYPQRALWAGVRT--------------------------------------------- 186

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 247 ddaAFLARLQQAFgWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVGRAL 326
Cdd:COG0654  187 ---ELRARLAAAG-PRLGELLELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAAL 262

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 752544915 327 TAGediGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKA 389
Cdd:COG0654  263 RGR---DDEAALARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLKG 322
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 9-314 6.15e-11

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 63.11  E-value: 6.15e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915    9 VDVAIVGGGMSGAVlalslaalpgpkpLQILLLEASAPE--LNAHPGF--DARAIALSAGTCEALARHGLWSRFAPHCSP 84
Cdd:pfam01494   2 TDVLIVGGGPAGLM-------------LALLLARAGVRVvlVERHATTsvLPRAHGLNQRTMELLRQAGLEDRILAEGVP 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   85 ISQIhvsdrGHFGQAGLTAAEYGLPALGQvielsaagialqqAIAACPQ---IRML------CPAQLE---RVEPLTE-- 150
Cdd:pfam01494  69 HEGM-----GLAFYNTRRRADLDFLTSPP-------------RVTVYPQtelEPILvehaeaRGAQVRfgtEVLSLEQdg 130

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  151 -GVNLTL---AGGERYQTR--LLVAADGGNSFVRQQCKLAVSRHDYGQSAIIATV-------KTAEDPAGRAFERFTQGG 217
Cdd:pfam01494 131 dGVTAVVrdrRDGEEYTVRakYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLfdapdlsDPVERAFVHYLIYAPHSR 210

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  218 PLALLPMQGGLSS-----LVWSVARDEAPALMALDDAAflARLQQAFGWRLGRfLQTGQRHVYPLVLTVADYPLAQRTVL 292
Cdd:pfam01494 211 GFMVGPWRSAGREryyvqVPWDEEVEERPEEFTDEELK--QRLRSIVGIDLAL-VEILWKSIWGVASRVATRYRKGRVFL 287

                         330       340
                  ....*....|....*....|..
gi 752544915  293 VGNAAHLLHPIAGQGFNLGMRD 314
Cdd:pfam01494 288 AGDAAHIHPPTGGQGLNTAIQD 309
 
Name Accession Description Interval E-value
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 7-401 5.39e-179

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 503.62  E-value: 5.39e-179
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   7 NHVDVAIVGGGMSGAVLALSLAALPGPKpLQILLLEASAPELNAHPGFDARAIALSAGTCEALARHGLWSRFAPHCSPIS 86
Cdd:PRK05732   2 SRMDVIIVGGGMAGATLALALSRLSHGG-LPVALIEAFAPESDAHPGFDARAIALAAGTCQQLARLGVWQALADCATPIT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  87 QIHVSDRGHFGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLCPAQLERVEPLTEGVNLTLAGGERYQTRL 166
Cdd:PRK05732  81 HIHVSDRGHAGFVRLDAEDYGVPALGYVVELHDVGQRLFALLDKAPGVTLHCPARVANVERTQGSVRVTLDDGETLTGRL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 167 LVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGGLSSLVWSVARDEAPALMAL 246
Cdd:PRK05732 161 LVAADGSHSALREALGIDWQQHPYEQVAVIANVTTSEAHQGRAFERFTEHGPLALLPMSDGRCSLVWCHPLEDAEEVLSW 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 247 DDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVGRAL 326
Cdd:PRK05732 241 SDAQFLAELQQAFGWRLGRITHAGKRSAYPLALVTAAQQISHRLALVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQAL 320

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 752544915 327 TAGEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLASRTLGFVAD 401
Cdd:PRK05732 321 ARGEDIGDYAVLQRYQQRRQQDREATIGFTDGLVRLFANRWAPLVVGRNLGLMAMDLLPPARDWLARRTLGWVAR 395
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 10-397 2.97e-149

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 427.89  E-value: 2.97e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   10 DVAIVGGGMSGAVLALSLAALPGpkpLQILLLEASAPElNAHPGFDARAIALSAGTCEALARHGLWSRFAPHCSPISQIH 89
Cdd:TIGR01984   1 DVIIVGGGLVGLSLALALSRLGK---IKIALIEANSPS-AAQPGFDARSLALSYGSKQILEKLGLWPKLAPFATPILDIH 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   90 VSDRGHFGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLCPAQLERVEPLTEGVNLTLAGGERYQTRLLVA 169
Cdd:TIGR01984  77 VSDQGHFGATHLRASEFGLPALGYVVELADLGQALLSRLALLTNIQLYCPARYKEIIRNQDYVRVTLDNGQQLRAKLLIA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  170 ADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGG-LSSLVWSVARDEAPALMALDD 248
Cdd:TIGR01984 157 ADGANSKVRELLSIPTEEHDYNQTALIANIRHEQPHQGCAFERFTPHGPLALLPLKDNyRSSLVWCLPSKQADTIANLPD 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  249 AAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVgraLTA 328
Cdd:TIGR01984 237 AEFLAELQQAFGWRLGKITQVGERKTYPLKLRIAETHVHPRVVLIGNAAQTLHPIAGQGFNLGLRDVETLAEVL---IDA 313

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 752544915  329 GEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLASRTLG 397
Cdd:TIGR01984 314 RIDLGTYALLQEYLRRRQFDQFITIGLTDGLNRLFSNHIPLLRALRNLGLLALENFPPLKKRLARQAMG 382
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 10-397 1.34e-142

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 411.21  E-value: 1.34e-142
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   10 DVAIVGGGMSGAVLALSLAAlpgpKPLQILLLEASAPELNAHPGFDARAIALSAGTCEALARHGLWSRFAP-HCSPISQI 88
Cdd:TIGR01988   1 DIVIVGGGMVGLALALALAR----SGLKVALIEATPLPAPADPGFDNRVSALSAASIRLLEKLGVWDKIEPaRAQPIRDI 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   89 HVSDRGHFGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLCPAQLERVEPLTEGVNLTLAGGERYQTRLLV 168
Cdd:TIGR01988  77 HVSDGGSFGALRFDADEIGLEALGYVVENRVLQQALWERLQELPNVTLLCPARVVELPRHSDHVELTLDDGQQLRARLLV 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  169 AADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGGLSSLVWSVARDEAPALMALDD 248
Cdd:TIGR01988 157 GADGANSKVRQLAGIPTTGWDYGQSAVVANVKHERPHQGTAWERFTPTGPLALLPLPDNRSSLVWTLPPEEAERLLALSD 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  249 AAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVGRALTA 328
Cdd:TIGR01988 237 EEFLAELQRAFGSRLGAITLVGERHAFPLSLTHAKRYVAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVLEDARRR 316

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 752544915  329 GEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLASRTLG 397
Cdd:TIGR01988 317 GEDIGSLRVLQRYERRRRFDNAAMLGATDGLNRLFSNDFPPLRLLRNLGLRLLNNLPPLKNFIARYAMG 385
PRK07364 PRK07364
FAD-dependent hydroxylase;
4-388 1.62e-82

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 258.80  E-value: 1.62e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   4 SDLNHVDVAIVGGGMSGAVLALSLAALPgpkpLQILLLEASAPELNAHPGfdaRAIALSAGTCEALARHGLWSRFAPHCS 83
Cdd:PRK07364  14 TRSLTYDVAIVGGGIVGLTLAAALKDSG----LRIALIEAQPAEAAAAKG---QAYALSLLSARIFEGIGVWEKILPQIG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  84 PISQIHVSDRGHFGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLCPAQLERVEPLTEGVNLTL--AGGER 161
Cdd:PRK07364  87 KFRQIRLSDADYPGVVKFQPTDLGTEALGYVGEHQVLLEALQEFLQSCPNITWLCPAEVVSVEYQQDAATVTLeiEGKQQ 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 162 -YQTRLLVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGGLSSLVWSVARDEA 240
Cdd:PRK07364 167 tLQSKLVVAADGARSPIRQAAGIKTKGWKYWQSCVTATVKHEAPHNDIAYERFWPSGPFAILPLPGNRCQIVWTAPHAQA 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 241 PALMALDDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTR 320
Cdd:PRK07364 247 KALLALPEAEFLAELQQRYGDQLGKLELLGDRFLFPVQLMQSDRYVQHRLALVGDAAHCCHPVGGQGLNLGIRDAAALAQ 326

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 752544915 321 AVGRALTAGEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLK 388
Cdd:PRK07364 327 VLQTAHQRGEDIGSLAVLKRYERWRKRENWLILGFTDLLDRLFSNQWWPLVVVRRLGLWLLRHVPPLK 394
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
10-392 3.79e-77

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 244.21  E-value: 3.79e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  10 DVAIVGGGMSGAVLALSLAALPGPKPLQILLLEASAPELNAHpgfDARAIALSAGTCEALARHGLWSRFAphcSPISQIH 89
Cdd:PRK06996  13 DIAIVGAGPVGLALAGWLARRSATRALSIALIDAREPAASAN---DPRAIALSHGSRVLLETLGAWPADA---TPIEHIH 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  90 VSDRGHFGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACPQ---IRMLCPAQLERVEPLTegVNLTLAGGER-YQTR 165
Cdd:PRK06996  87 VSQRGHFGRTLIDRDDHDVPALGYVVRYGSLVAALARAVRGTPVrwlTSTTAHAPAQDADGVT--LALGTPQGARtLRAR 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 166 LLVAADGG--NSFVRQQCKLAVSRhDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPM---QGGLSSLVWSVARDEA 240
Cdd:PRK06996 165 IAVQAEGGlfHDQKADAGDSARRR-DYGQTAIVGTVTVSAPRPGWAWERFTHEGPLALLPLggpRQADYALVWCCAPDEA 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 241 PALMALDDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTR 320
Cdd:PRK06996 244 ARRAALPDDAFLAELGAAFGTRMGRFTRIAGRHAFPLGLNAARTLVNGRIAAVGNAAQTLHPVAGQGLNLGLRDAHTLAD 323

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 752544915 321 AVGRALTAGEDIGSFEvlsgywQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLA 392
Cdd:PRK06996 324 ALSDHGATPLALATFA------ARRALDRRVTIGATDLLPRLFTVDSRPLAHLRGAALTALEFVPPLKHALA 389
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
10-397 3.90e-69

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 223.29  E-value: 3.90e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  10 DVAIVGGGMSGAVLALSLAALPgpkpLQILLLEASAPELNAHPGFDARAIALSAGTCEALARHGLW-----SRFAPhcsp 84
Cdd:PRK07608   7 DVVVVGGGLVGASLALALAQSG----LRVALLAPRAPPRPADDAWDSRVYAISPSSQAFLERLGVWqaldaARLAP---- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  85 isqihVSDRGHFGQAG----LTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLcPAQLERVEPLTEGVNLTLAGGE 160
Cdd:PRK07608  79 -----VYDMRVFGDAHarlhFSAYQAGVPQLAWIVESSLIERALWAALRFQPNLTWF-PARAQGLEVDPDAATLTLADGQ 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 161 RYQTRLLVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGGLSSLVWSVARDEA 240
Cdd:PRK07608 153 VLRADLVVGADGAHSWVRSQAGIKAERRPYRQTGVVANFKAERPHRGTAYQWFRDDGILALLPLPDGHVSMVWSARTAHA 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 241 PALMALDDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTR 320
Cdd:PRK07608 233 DELLALSPEALAARVERASGGRLGRLECVTPAAGFPLRLQRVDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVAALAD 312

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 752544915 321 AVGrALTAGEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLASRTLG 397
Cdd:PRK07608 313 VLA-GREPFRDLGDLRLLRRYERARREDILALQVATDGLQRLFALPGPLARWLRNAGMALVGALPLVKRWLVRHALG 388
PRK09126 PRK09126
FAD-dependent hydroxylase;
7-393 6.60e-69

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 222.51  E-value: 6.60e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   7 NHVDVAIVGGGMSGAVLALSLAALPgpkpLQILLLEASAPELNAHPGFDARAIALSAGTCEALARHGLWSRFAPH-CSPI 85
Cdd:PRK09126   2 MHSDIVVVGAGPAGLSFARSLAGSG----LKVTLIERQPLAALADPAFDGREIALTHASREILQRLGAWDRIPEDeISPL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  86 SQIHVSDRGHFGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLCPAQLERVEPLTEGVNLTLAGGERYQTR 165
Cdd:PRK09126  78 RDAKVLNGRSPFALTFDARGRGADALGYLVPNHLIRRAAYEAVSQQDGIELLTGTRVTAVRTDDDGAQVTLANGRRLTAR 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 166 LLVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGGLSSLVWSVARDEAPALMA 245
Cdd:PRK09126 158 LLVAADSRFSATRRQLGIGADMHDFGRTMLVCRMRHELPHHHTAWEWFGYGQTLALLPLNGHLSSLVLTLPPDQIEALLA 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 246 LDDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVGRA 325
Cdd:PRK09126 238 LDPEAFAAEVTARFKGRLGAMRLVSSRHAYPLVAVYAHRFVAKRFALIGDAAVGMHPVTAHGFNLGLKGQDILARLILAA 317

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 752544915 326 LTAGEDIGSFEVLSGYwqqRKGDQAQTVWL---TSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLAS 393
Cdd:PRK09126 318 ARRGQDIGAASLLERY---ERKHRLATRPLyhaTNAIAALYTDDRPPARLLRRAVLRAANRFPPLKQAIAK 385
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
10-388 3.90e-68

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 221.01  E-value: 3.90e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  10 DVAIVGGGMSGAVLALSLAALpGPKpLQILLLEAsAPELNahPGFDARAIALSAGTCEALARHGLWSRFAPHCSPISQIH 89
Cdd:PRK07333   3 DVVIAGGGYVGLALAVALKQA-APH-LPVTVVDA-APAGA--WSRDPRASAIAAAARRMLEALGVWDEIAPEAQPITDMV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  90 VSD-------RGHF----GQ-------AGLTAAEYGLPALGQVIElsAAGIALQQAIAAcpqirmlcpaqlERVEPLTEG 151
Cdd:PRK07333  78 ITDsrtsdpvRPVFltfeGEvepgepfAHMVENRVLINALRKRAE--ALGIDLREATSV------------TDFETRDEG 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 152 VNLTLAGGERYQTRLLVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGGLSSL 231
Cdd:PRK07333 144 VTVTLSDGSVLEARLLVAADGARSKLRELAGIKTVGWDYGQSGIVCTVEHERPHGGRAEEHFLPAGPFAILPLKGNRSSL 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 232 VWSVARDEAPALMALDDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLG 311
Cdd:PRK07333 224 VWTERTADAERLVALDDLVFEAELEQRFGHRLGELKVLGKRRAFPLGLTLARSFVAPRFALVGDAAHGIHPIAGQGLNLG 303

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 752544915 312 MRDLDLLTRAVGRALTAGEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLK 388
Cdd:PRK07333 304 LKDVAALAEVVVEAARLGLDIGSLDVLERYQRWRRFDTVRMGVTTDVLNRLFSNDSTLLRSVRDIGLGLVDRLPKLK 380
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 1-397 6.22e-67

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 218.10  E-value: 6.22e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   1 MSQSdlnhVDVAIVGGGMSGAVLALSLAAlpgpKPLQILLLEASAPELNAHPGFDARAIALSAGTCEALARHGLWSRF-A 79
Cdd:PRK08850   1 MMQS----VDVAIIGGGMVGLALAAALKE----SDLRIAVIEGQLPEEALNELPDVRVSALSRSSEHILRNLGAWQGIeA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  80 PHCSPISQIHVSDRGHFGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLCPAQLERVEPLTEGVNLTLAGG 159
Cdd:PRK08850  73 RRAAPYIAMEVWEQDSFARIEFDAESMAQPDLGHIVENRVIQLALLEQVQKQDNVTLLMPARCQSIAVGESEAWLTLDNG 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 160 ERYQTRLLVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPM-QGGLSSLVWSVARD 238
Cdd:PRK08850 153 QALTAKLVVGADGANSWLRRQMDIPLTHWDYGHSALVANVRTVDPHNSVARQIFTPQGPLAFLPMsEPNMSSIVWSTEPL 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 239 EAPALMALDDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLL 318
Cdd:PRK08850 233 RAEALLAMSDEQFNKALTAEFDNRLGLCEVVGERQAFPLKMRYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAASL 312

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 752544915 319 TRAVGRALTAGEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLASRTLG 397
Cdd:PRK08850 313 AQEILALWQQGRDIGLKRNLRGYERWRKAEAAKMIAAMQGFRDLFSGSNPAKKLVRGIGMSLAGQLPGAKDEIMKRALG 391
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
10-397 3.51e-61

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 202.79  E-value: 3.51e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  10 DVAIVGGGMSGAVLALSLAALPgpkpLQILLLEASAPELNAHPGFDARAIALSAGTCEALARHGLWSRF-APHCSPISQI 88
Cdd:PRK08773   8 DAVIVGGGVVGAACALALADAG----LSVALVEGREPPRWQADQPDLRVYAFAADNAALLDRLGVWPAVrAARAQPYRRM 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  89 HVSDRGHFGQAGLTAAEYGLPALGQVIElsaAGIALQQAIAACPQ--IRMLCPAQLERVEPLTEGVNLTLAGGERYQTRL 166
Cdd:PRK08773  84 RVWDAGGGGELGFDADTLGREQLGWIVE---NDLLVDRLWAALHAagVQLHCPARVVALEQDADRVRLRLDDGRRLEAAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 167 LVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGGLSSLVWSVARDEAPALMAL 246
Cdd:PRK08773 161 AIAADGAASTLRELAGLPVSRHDYAQRGVVAFVDTEHPHQATAWQRFLPTGPLALLPFADGRSSIVWTLPDAEAERVLAL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 247 DDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVGRAL 326
Cdd:PRK08773 241 DEAAFSRELTQAFAARLGEVRVASPRTAFPLRRQLVQQYVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQLVRQAH 320

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 752544915 327 TAGEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLASRTLG 397
Cdd:PRK08773 321 ARRADWAAPHRLQRWARTRRSDNTVAAYGFDAINRVFSNDEMHLTLLRGSVLGLAGKLPPLVDALWKRASG 391
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 8-402 4.10e-61

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 202.75  E-value: 4.10e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   8 HVDVAIVGGGMSGAVLALSLAAlpgpKPLQILLLEA---SAPELNAHPGFDARAIALSAGTCEALARHGLWSRFAPH-CS 83
Cdd:PRK05714   2 RADLLIVGAGMVGSALALALQG----SGLEVLLLDGgplSVKPFDPQAPFEPRVSALSAASQRILERLGAWDGIAARrAS 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  84 PISQIHVSDRGHFGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACpQIRMLCPAQLERVEPLTEGVNLTLAGGERYQ 163
Cdd:PRK05714  78 PYSEMQVWDGSGTGQIHFSAASVHAEVLGHIVENRVVQDALLERLHDS-DIGLLANARLEQMRRSGDDWLLTLADGRQLR 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 164 TRLLVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPM----QGGLSSLVWSVARDE 239
Cdd:PRK05714 157 APLVVAADGANSAVRRLAGCATREWDYLHHAIVTSVRCSEPHRATAWQRFTDDGPLAFLPLerdgDEHWCSIVWSTTPEE 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 240 APALMALDDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLT 319
Cdd:PRK05714 237 AERLMALDDDAFCAALERAFEGRLGEVLSADPRLCVPLRQRHAKRYVEPGLALIGDAAHTIHPLAGQGVNLGFLDAAVLA 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 320 RAVGRALTAGEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLASRTLGFV 399
Cdd:PRK05714 317 EVLLHAAERGERLADVRVLSRFERRRMPHNLALMAAMEGFERLFQADPLPLRWLRNTGLKLVDQMPEAKALFVRQALGLS 396


                 ...
gi 752544915 400 ADV 402
Cdd:PRK05714 397 GDL 399
PRK08013 PRK08013
oxidoreductase; Provisional
 9-397 1.12e-55

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 188.33  E-value: 1.12e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   9 VDVAIVGGGMSGAVLALSLAALPgpkpLQILLLEASAPE-LNAHPGFDARAIALSAGTCEALARHGLWSRF-APHCSPIS 86
Cdd:PRK08013   4 VDVVIAGGGMVGLAVACGLQGSG----LRVAVLEQRVPEpLAADAPPALRVSAINAASEKLLTRLGVWQDIlARRASCYH 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  87 QIHVSDRGHFGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLCPAQLERVEPLTEGVNLTLAGGERYQTRL 166
Cdd:PRK08013  80 GMEVWDKDSFGRIAFDDQSMGYSHLGHIIENSVIHYALWQKAQQSSDITLLAPAELQQVAWGENEAFLTLKDGSMLTARL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 167 LVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGG-LSSLVWSVARDEAPALMA 245
Cdd:PRK08013 160 VVGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGDGILAFLPLSDPhLCSIVWSLSPEEAQRMQQ 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 246 LDDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVGRA 325
Cdd:PRK08013 240 APEEEFNRALAIAFDNRLGLCELESERQVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELRRL 319

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 752544915 326 LTAGEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLASRTLG 397
Cdd:PRK08013 320 HRQGKDIGQHLYLRRYERSRKHSAALMLAGMQGFRDLFAGNNPAKKLLRDIGLKLADTLPGVKPQLIRQAMG 391
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 10-388 1.27e-55

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 189.20  E-value: 1.27e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   10 DVAIVGGGMSGAVLALSLAALPGPKPLQILLLEA-SAPEL-----NAHPG-FDARAIALSAGTCEALARHGLWSRFAPH- 81
Cdd:TIGR01989   2 DVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAvDNPKLksrnyEKPDGpYSNRVSSITPASISFFKKIGAWDHIQSDr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   82 CSPISQIHVSDrghfgqaGLTAAEY------GLPALGQVIELSAAGIALQQAIAACPQ--IRMLCPAQLERV-------- 145
Cdd:TIGR01989  82 IQPFGRMQVWD-------GCSLALIrfdrdnGKEDMACIIENDNIQNSLYNRLQEYNGdnVKILNPARLISVtipskypn 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  146 --EPLTEgvnLTLAGGERYQTRLLVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVK--TAEDPAgRAFERFTQGGPLAL 221
Cdd:TIGR01989 155 dnSNWVH---ITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKleEATEND-VAWQRFLPTGPIAL 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  222 LPMQGGLSSLVWSVARDEAPALMALDDAAFLARLQQAF--GW----RLGRFLQTGQ------------------------ 271
Cdd:TIGR01989 231 LPLPDNNSTLVWSTSPEEALRLLSLPPEDFVDALNAAFdlGYsdhpYSYLLDYAMEklnedigfrtegskscfqvpprvi 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  272 ------RHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVGRALTAGEDIGSFEVLSGYWQQR 345
Cdd:TIGR01989 311 gvvdksRAAFPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERER 390

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 752544915  346 KGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLK 388
Cdd:TIGR01989 391 YAKNVVLLGLVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLK 433
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 7-388 3.99e-55

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 186.73  E-value: 3.99e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   7 NHVDVAIVGGGMSGAVLALSLAALPgpkpLQILLLEASAP-ELNAHPGFDARAIALSAGTCEALARHGLWSRF-APHCSP 84
Cdd:PRK08020   4 QPTDIAIVGGGMVGAALALGLAQHG----FSVAVLEHAAPaPFDADSQPDVRISAISAASVALLKGLGVWDAVqAMRSHP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  85 ISQIHVSDRgHFGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLCPAQLERVEPLTEGVNLTLAGGERYQT 164
Cdd:PRK08020  80 YRRLETWEW-ETAHVVFDAAELKLPELGYMVENRVLQLALWQALEAHPNVTLRCPASLQALQRDDDGWELTLADGEEIQA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 165 RLLVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGGLSSLVWSvardEAPA-- 242
Cdd:PRK08020 159 KLVIGADGANSQVRQMAGIGVHGWQYRQSCMLISVKCENPPGDSTWQQFTPSGPRAFLPLFDNWASLVWY----DSPAri 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 243 --LMALDDAAFLARLQQAFGWRLGRflqtgqrhVYPLVltVADYPLAQR---------TVLVGNAAHLLHPIAGQGFNLG 311
Cdd:PRK08020 235 rqLQAMSMAQLQQEIAAHFPARLGA--------VTPVA--AGAFPLTRRhalqyvqpgLALVGDAAHTINPLAGQGVNLG 304

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 312 MRDLDLLTRAVGRALTAGEDIGSFEVLSGYWQQRKGDQaqtvWLTSSLAQL----FSNDHDPLVAGRNLALSLMGRLSCL 387
Cdd:PRK08020 305 YRDVDALLDVLVNARSYGEAWASEAVLKRYQRRRMADN----LLMQSGMDLfyagFSNNLPPLRFARNLGLMAAQRAGVL 380


                 .
gi 752544915 388 K 388
Cdd:PRK08020 381 K 381
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 8-389 1.01e-54

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 183.60  E-value: 1.01e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   8 HVDVAIVGGGMSGAVLALSLAAlpgpKPLQILLLEASAPelnahPGFDARAIALSAGTCEALARHGLWSRFAPHCSPISQ 87
Cdd:COG0654    3 RTDVLIVGGGPAGLALALALAR----AGIRVTVVERAPP-----PRPDGRGIALSPRSLELLRRLGLWDRLLARGAPIRG 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  88 IHVSDRGHFGQ-AGLTAAEYGLPAlGQVIELSAAGIALQQAIAACPqIRMLCPAQLERVEPLTEGVNLTLAGGERYQTRL 166
Cdd:COG0654   74 IRVRDGSDGRVlARFDAAETGLPA-GLVVPRADLERALLEAARALG-VELRFGTEVTGLEQDADGVTVTLADGRTLRADL 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 167 LVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTaedpagraferftqggplallpmqgglsslvwsvardeapalmal 246
Cdd:COG0654  152 VVGADGARSAVRRLLGIGFTGRDYPQRALWAGVRT--------------------------------------------- 186

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 247 ddaAFLARLQQAFgWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVGRAL 326
Cdd:COG0654  187 ---ELRARLAAAG-PRLGELLELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAAL 262

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 752544915 327 TAGediGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKA 389
Cdd:COG0654  263 RGR---DDEAALARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLKG 322
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 6-398 5.44e-47

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 165.33  E-value: 5.44e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   6 LNHVDVAIVGGGMSGAVLALSLAAlpgpKPLQILLLEASAPE-LNAHPGFDARAIALSAGTCEALARHGLWS-----RFA 79
Cdd:PRK08849   1 MNKYDIAVVGGGMVGAATALGFAK----QGRSVAVIEGGEPKaFEPSQPMDIRVSAISQTSVDLLESLGAWSsivamRVC 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  80 PHCSPISQIHVSDRGHFgqaglTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLCPAQLERVEPLTEGVNLTLAGG 159
Cdd:PRK08849  77 PYKRLETWEHPECRTRF-----HSDELNLDQLGYIVENRLIQLGLWQQFAQYPNLTLMCPEKLADLEFSAEGNRVTLESG 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 160 ERYQTRLLVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGGLSSLVWSVARDE 239
Cdd:PRK08849 152 AEIEAKWVIGADGANSQVRQLAGIGITAWDYRQHCMLINVETEQPQQDITWQQFTPSGPRSFLPLCGNQGSLVWYDSPKR 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 240 APALMALDDAAFLARLQQAFGWRLGRF--LQTGQrhvYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDL 317
Cdd:PRK08849 232 IKQLSAMNPEQLRSEILRHFPAELGEIkvLQHGS---FPLTRRHAQQYVKNNCVLLGDAAHTINPLAGQGVNLGFKDVDV 308

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 318 LTRAvgralTAGEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLASRTLG 397
Cdd:PRK08849 309 LLAE-----TEKQGVLNDASFARYERRRRPDNLLMQTGMDLFYKTFSNSLTPLKFVRNAALKLAENSGPLKTQVLKYALG 383


                 .
gi 752544915 398 F 398
Cdd:PRK08849 384 M 384
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
7-348 4.75e-45

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 160.07  E-value: 4.75e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   7 NHVDVAIVGGGMSGavlalslaalpgpkplqilLLEASAPelnAHPGF------------DARAIALSAGTCEALARHGL 74
Cdd:PRK07494   6 EHTDIAVIGGGPAG-------------------LAAAIAL---ARAGAsvalvapeppyaDLRTTALLGPSIRFLERLGL 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  75 WSRFAPHCSPISQIHVSDRG---------HFgqaglTAAEYGLPALGQVIELSAAGIALQQAIAACPQIRMLcPAQLERV 145
Cdd:PRK07494  64 WARLAPHAAPLQSMRIVDATgrlirapevRF-----RAAEIGEDAFGYNIPNWLLNRALEARVAELPNITRF-GDEAESV 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 146 EPLTEGVNLTLAGGERYQTRLLVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQ 225
Cdd:PRK07494 138 RPREDEVTVTLADGTTLSARLVVGADGRNSPVREAAGIGVRTWSYPQKALVLNFTHSRPHQNVSTEFHTEGGPFTQVPLP 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 226 GGLSSLVWSVARDEAPALMALDDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAG 305
Cdd:PRK07494 218 GRRSSLVWVVRPAEAERLLALSDAALSAAIEERMQSMLGKLTLEPGRQAWPLSGQVAHRFAAGRTALVGEAAHVFPPIGA 297

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|...
gi 752544915 306 QGFNLGMRDLDLLTRAVGRaltAGEDIGSFEVLSGYWQQRKGD 348
Cdd:PRK07494 298 QGLNLGLRDVATLVEIVED---RPEDPGSAAVLAAYDRARRPD 337
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 10-397 5.60e-21

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 93.45  E-value: 5.60e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  10 DVAIVGGGMSGAVLALSLAAlpgpKPLQILLLEASAPElnaHPGF--DARAIALSAGTCEALARHGLWSRFAPHCSPISQ 87
Cdd:PRK06617   3 NTVILGCGLSGMLTALSFAQ----KGIKTTIFESKSVK---SPEFfkDIRTTALTPHSKNFLFSIDIWEELEKFVAEMQD 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  88 IHVSDRGHFGQAGLTAAEYGLpaLGQVIELSAAGIALQQAIAACPQIRMLCPAQLERVEPlTEGVNLTLAGGERYQTRLL 167
Cdd:PRK06617  76 IYVVDNKASEILDLRNDADAV--LGYVVKNSDFKKILLSKITNNPLITLIDNNQYQEVIS-HNDYSIIKFDDKQIKCNLL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 168 VAADGGNSFVRQQCKLAVSRHDYgQSAIIATVKTAEDPAGRAFERFTQGGPLALLPMQGGL-SSLVWSVARDEAPALMAL 246
Cdd:PRK06617 153 IICDGANSKVRSHYFANEIEKPY-QTALTFNIKHEKPHENCAMEHFLPLGPFALLPLKDQYaSSVIWSTSSDQAALIVNL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 247 --DDAAFLArlQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVGR 324
Cdd:PRK06617 232 pvEEVRFLT--QRNAGNSLGKITIDSEISSFPLKARIANRYFHNRIVLIADTAHTVHPLAGQGLNQGIKDIEILSMIVSN 309

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 752544915 325 ALTagedigsfevLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHDPLVAGRNLALSLMGRLSCLKAPLASRTLG 397
Cdd:PRK06617 310 NGT----------LQEYQKLRQEDNFIMYKLTDELNNIFSNYSKNLRCLRQIGFKVINNFKPIKNLITSYAMG 372
PRK07045 PRK07045
putative monooxygenase; Reviewed
 132-383 2.79e-13

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 70.71  E-value: 2.79e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 132 PQIRMLCPAQLERVEPLTEGV--NLTLAGGERYQTRLLVAADGGNSFVRQQC-KLAVSRHDYGQSAIIATVKTAedPAGR 208
Cdd:PRK07045 120 PNVRLRFETSIERIERDADGTvtSVTLSDGERVAPTVLVGADGARSMIRDDVlRMPAERVPYATPMAFGTIALT--DSVR 197

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 209 AFERF---TQGGPLALLPMQGGLSSLVWSVARDEAPALMA-LDDAAFLARLQQAFGWR----LGRFLQTGQRHVYPLVLT 280
Cdd:PRK07045 198 ECNRLyvdSNQGLAYFYPIGDQATRLVVSFPADEMQGYLAdTTRTKLLARLNEFVGDEsadaMAAIGAGTAFPLIPLGRM 277

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 281 VADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVGRALTagEDIGSFEVLSGYWQQRKGDQAQTVWLTSSLA 360
Cdd:PRK07045 278 NLDRYHKRNVVLLGDAAHSIHPITGQGMNLAIEDAGELGACLDLHLS--GQIALADALERFERIRRPVNEAVISYGHALA 355

                        250       260
                 ....*....|....*....|...
gi 752544915 361 QLFsNDHDPLVAGRNLALSLMGR 383
Cdd:PRK07045 356 TTY-HDRAALVANFRSQLQTSGR 377
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 9-314 6.15e-11

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 63.11  E-value: 6.15e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915    9 VDVAIVGGGMSGAVlalslaalpgpkpLQILLLEASAPE--LNAHPGF--DARAIALSAGTCEALARHGLWSRFAPHCSP 84
Cdd:pfam01494   2 TDVLIVGGGPAGLM-------------LALLLARAGVRVvlVERHATTsvLPRAHGLNQRTMELLRQAGLEDRILAEGVP 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   85 ISQIhvsdrGHFGQAGLTAAEYGLPALGQvielsaagialqqAIAACPQ---IRML------CPAQLE---RVEPLTE-- 150
Cdd:pfam01494  69 HEGM-----GLAFYNTRRRADLDFLTSPP-------------RVTVYPQtelEPILvehaeaRGAQVRfgtEVLSLEQdg 130

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  151 -GVNLTL---AGGERYQTR--LLVAADGGNSFVRQQCKLAVSRHDYGQSAIIATV-------KTAEDPAGRAFERFTQGG 217
Cdd:pfam01494 131 dGVTAVVrdrRDGEEYTVRakYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLfdapdlsDPVERAFVHYLIYAPHSR 210

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  218 PLALLPMQGGLSS-----LVWSVARDEAPALMALDDAAflARLQQAFGWRLGRfLQTGQRHVYPLVLTVADYPLAQRTVL 292
Cdd:pfam01494 211 GFMVGPWRSAGREryyvqVPWDEEVEERPEEFTDEELK--QRLRSIVGIDLAL-VEILWKSIWGVASRVATRYRKGRVFL 287

                         330       340
                  ....*....|....*....|..
gi 752544915  293 VGNAAHLLHPIAGQGFNLGMRD 314
Cdd:pfam01494 288 AGDAAHIHPPTGGQGLNTAIQD 309
PRK06834 PRK06834
hypothetical protein; Provisional
 56-314 1.26e-10

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 62.73  E-value: 1.26e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  56 ARAIALSAGTCEALARHGLWSRFaphcspISQIHVSDRGHFGQAGL------TAAEYGLPALGQVIELSAAGIALQQAIA 129
Cdd:PRK06834  43 SRAGGLHARTLEVLDQRGIADRF------LAQGQVAQVTGFAATRLdisdfpTRHNYGLALWQNHIERILAEWVGELGVP 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 130 ACPQIRMLCPAQLErvepltEGVNLTLAGGERYQTRLLVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAG-- 207
Cdd:PRK06834 117 IYRGREVTGFAQDD------TGVDVELSDGRTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEMTEEPEWgv 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 208 -------RAFERFTQGGPLALLPMQGglsslvwSVARDEAPALMALDDAaflarLQQAFG---------WrLGRFLQTGQ 271
Cdd:PRK06834 191 hrdalgiHAFGRLEDEGPVRVMVTEK-------QVGATGEPTLDDLREA-----LIAVYGtdygihsptW-ISRFTDMAR 257

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 752544915 272 RhvyplvltvADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRD 314
Cdd:PRK06834 258 Q---------AASYRDGRVLLAGDAAHVHSPVGGQGLNTGVQD 291
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
7-314 1.42e-10

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 62.62  E-value: 1.42e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   7 NHVDVAIVGGGMSGAVLALSLaalpGPKPLQILLLEAsAPELNAHPgfdaRAIALSAGTCEALARHGLWSRFAPHCSP-- 84
Cdd:PRK06183   9 HDTDVVIVGAGPVGLTLANLL----GQYGVRVLVLER-WPTLYDLP----RAVGIDDEALRVLQAIGLADEVLPHTTPnh 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  85 -----------ISQIHVSDRGHFG--------QAGLTAAeyglpalgqvielsaagiaLQQAIAACPQIRMLCPAQLERV 145
Cdd:PRK06183  80 gmrfldakgrcLAEIARPSTGEFGwprrnafhQPLLEAV-------------------LRAGLARFPHVRVRFGHEVTAL 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 146 EPLTEGVNLTL--AGGERYQTR--LLVAADGGNSFVRQQckLAVSRHDYGQSA--IIATVKTAEDPAGRAFER------- 212
Cdd:PRK06183 141 TQDDDGVTVTLtdADGQRETVRarYVVGCDGANSFVRRT--LGVPFEDLTFPErwLVVDVLIANDPLGGPHTYqycdpar 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 213 ---FTQGGP------LALLPmqgglsslvwsvarDEAPAlmALDDAAFLARLqqafgwrLGRFLQTGQ-----RH-VYPL 277
Cdd:PRK06183 219 pytSVRLPHgrrrweFMLLP--------------GETEE--QLASPENVWRL-------LAPWGPTPDdaeliRHaVYTF 275

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 752544915 278 VLTVADYPLAQRTVLVGNAAHLLHPIAGQGFNLGMRD 314
Cdd:PRK06183 276 HARVADRWRSGRVLLAGDAAHLMPPFAGQGMNSGIRD 312
PRK08244 PRK08244
monooxygenase;
9-314 1.81e-07

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 52.82  E-value: 1.81e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915   9 VDVAIVGGGMSGAVLALSLAALpGPKPLQILLLEASAPelnahpgfDARAIALSAGTCEALARHGLWSRFAPHCSPISqi 88
Cdd:PRK08244   3 YEVIIIGGGPVGLMLASELALA-GVKTCVIERLKETVP--------YSKALTLHPRTLEILDMRGLLERFLEKGRKLP-- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  89 hvsdRGHFgqAGLTAAeyglpalgqvIELSAAGialqqaiAACPQIRMLCPAQLERV----------------EPLT--- 149
Cdd:PRK08244  72 ----SGHF--AGLDTR----------LDFSALD-------TSSNYTLFLPQAETEKVleeharslgveifrgaEVLAvrq 128

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 150 --EGVNLTLAG--GERYQTRL-LVAADGGNSFVRQQCKLAVSRHDYGQSAIIATVKTAEDPAGRAFERFTQGGPLALLPM 224
Cdd:PRK08244 129 dgDGVEVVVRGpdGLRTLTSSyVVGADGAGSIVRKQAGIAFPGTDATFTAMLGDVVLKDPPPSSVLSLCTREGGVMIVPL 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 225 QGGLSS-LVWSVARDEAPALMALDDAAFLARLQQAFGWRLG--------RFLQTGQRhvyplvltvADYPLAQRTVLVGN 295
Cdd:PRK08244 209 SGGIYRvLIIDPERPQVPKDEPVTLEELKTSLIRICGTDFGlndpvwmsRFGNATRQ---------AERYRSGRIFLAGD 279

                        330
                 ....*....|....*....
gi 752544915 296 AAHLLHPIAGQGFNLGMRD 314
Cdd:PRK08244 280 AAHIHFPAGGQGLNVGLQD 298
PRK06184 PRK06184
hypothetical protein; Provisional
 149-314 6.45e-05

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 44.97  E-value: 6.45e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 149 TEGVNLTL---AGGERYQTRLLVAADGGNSFVRQQckLAVS---RHDYGQSAIIATVK-TAEDPAgrAFERFT--QGGPL 219
Cdd:PRK06184 139 ADGVTARVagpAGEETVRARYLVGADGGRSFVRKA--LGIGfpgETLGIDRMLVADVSlTGLDRD--AWHQWPdgDMGMI 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 220 ALLPMQGglSSLVWSVARDEAPALMALDDAAFLARLQQAFGWRLGRFLQTGQRHVYPLVLTVADYPLAQRTVLVGNAAHl 299
Cdd:PRK06184 215 ALCPLPG--TDLFQIQAPLPPGGEPDLSADGLTALLAERTGRTDIRLHSVTWASAFRMNARLADRYRVGRVFLAGDAAH- 291

                        170
                 ....*....|....*.
gi 752544915 300 LHPIAG-QGFNLGMRD 314
Cdd:PRK06184 292 VHPPAGgQGLNTSVQD 307
SE pfam08491
Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which ...
 291-375 5.61e-04

Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which are found in taxonomically diverse groups of eukaryotes and also in bacteria. SE was first cloned from Saccharomyces cerevisiae where it was named ERG1. It contains a putative FAD binding site and is a key enzyme in the sterol biosynthetic pathway. Putative transmembrane regions are found to the protein's C-terminus.


Pssm-ID: 400679  Cd Length: 276  Bit Score: 41.55  E-value: 5.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  291 VLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVG--RALTAGEDIgsFEVLSGYWQQRKGDQAQTVWLTSSLAQLFSNDHD 368
Cdd:pfam08491 133 ILLGDALNMRHPLTGGGMTVGLNDIVLLRKLLGplRDLSDREKV--SKVLKSFHWKRKPYDAVINTLSIALYSLFAADSD 210


                  ....*..
gi 752544915  369 PLVAGRN 375
Cdd:pfam08491 211 ELKALRK 217
PRK07190 PRK07190
FAD-binding protein;
140-183 8.45e-04

FAD-binding protein;


Pssm-ID: 235955 [Multi-domain]  Cd Length: 487  Bit Score: 41.34  E-value: 8.45e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 752544915 140 AQLERVEPLTEGVNLTLAGGERYQTRLLVAADGGNSFVRQQCKL 183
Cdd:PRK07190 130 TSVVNIELNQAGCLTTLSNGERIQSRYVIGADGSRSFVRNHFNV 173
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
123-180 1.13e-03

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 40.79  E-value: 1.13e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 752544915 123 ALQQAIAACPQIRMLCPAQLERVEPLTEGVNLTLAGGERYQTRLLVAADGGNSFVRQQ 180
Cdd:PRK08163 114 SLLEAVLDHPLVEFRTSTHVVGIEQDGDGVTVFDQQGNRWTGDALIGCDGVKSVVRQS 171
PRK06847 PRK06847
hypothetical protein; Provisional
 59-328 2.03e-03

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 39.86  E-value: 2.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915  59 IALSAGTCEALARHGLWSRFAPHCSPISQIHVSD-RGH--FGQAGLTAAEYGLPALGQVIELSAAGIALQQAIAACPQIR 135
Cdd:PRK06847  46 ITLQGNALRALRELGVLDECLEAGFGFDGVDLFDpDGTllAELPTPRLAGDDLPGGGGIMRPALARILADAARAAGADVR 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 136 MLCpaQLERVEPLTEGVNLTLAGGERYQTRLLVAADGGNSFVRQQCKLAVSRHDY-GQSAIIATVktaEDPAGraFERFT 214
Cdd:PRK06847 126 LGT--TVTAIEQDDDGVTVTFSDGTTGRYDLVVGADGLYSKVRSLVFPDEPEPEYtGQGVWRAVL---PRPAE--VDRSL 198

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 215 --QGGPLA--LLPMQGGLSSLVWSVARDEAPALMALDDAAFLARLQQAFGWRLGRFLQ---TGQRHVyplvltvaDY-PL 286
Cdd:PRK06847 199 myLGPTTKagVVPLSEDLMYLFVTEPRPDNPRIEPDTLAALLRELLAPFGGPVLQELReqiTDDAQV--------VYrPL 270

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 752544915 287 AQ----------RTVLVGNAAHLLHPIAGQGFNLGMRD----LDLLTRA--VGRALTA 328
Cdd:PRK06847 271 ETllvpapwhrgRVVLIGDAAHATTPHLAQGAGMAIEDaivlAEELARHdsLEAALQA 328
PRK07236 PRK07236
hypothetical protein; Provisional
 142-180 2.78e-03

hypothetical protein; Provisional


Pssm-ID: 235980 [Multi-domain]  Cd Length: 386  Bit Score: 39.52  E-value: 2.78e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 752544915 142 LERVEPLTEGVNLTLAGGERYQTRLLVAADGGNSFVRQQ 180
Cdd:PRK07236 121 LVGFEQDGDRVTARFADGRRETADLLVGADGGRSTVRAQ 159
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
124-343 4.52e-03

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 38.80  E-value: 4.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 124 LQQAIAAcpQIRMLCPAQLERVEPLTEGVNLTLAGGERYQTRLLVAADGGNSFVRQQCKLAVSRHDYGQSAI-----IAT 198
Cdd:COG0644   93 AEQAEEA--GAEVRTGTRVTDVLRDDGRVVVRTGDGEEIRADYVVDADGARSLLARKLGLKRRSDEPQDYALaikehWEL 170

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752544915 199 VKTAEDPAGRAFERFTQGGPLA---LLPMQGGLSSLvwsvardeapalmalddaaflarlqqafGWRLGRFlqtgQRHVY 275
Cdd:COG0644  171 PPLEGVDPGAVEFFFGEGAPGGygwVFPLGDGRVSV----------------------------GIPLGGP----RPRLV 218

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 752544915 276 plvltvadyplAQRTVLVGNAAHLLHPIAGQGFNLGMRDLDLLTRAVGRALTAGEDigSFEVLSGYWQ 343
Cdd:COG0644  219 -----------GDGVLLVGDAAGFVDPLTGEGIHLAMKSGRLAAEAIAEALEGGDF--SAEALAEYER 273
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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