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Conserved domains on  [gi|754290365|ref|WP_041849838|]
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ABC transporter permease [Bartonella bacilliformis]

Protein Classification

ABC transporter permease( domain architecture ID 10790725)

ABC transporter permease is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

Gene Ontology:  GO:0043190|GO:0140359|GO:0042626|GO:0016020|GO:0006826
PubMed:  25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CeuB COG4606
ABC-type enterochelin transport system, permease component [Inorganic ion transport and ...
 1-318 1.76e-142

ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 443656  Cd Length: 318  Bit Score: 404.50  E-value: 1.76e-142
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365   1 MKNYWIAIIAIILLSILSIFVGYSDITLSNLLLKDSTGWLLFWQTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPST 80
Cdd:COG4606    1 MKKLRLLILLLLVLSILSLFIGVSDVSLSDLLSLDPEALQILLISRLPRTLAILLAGASLSVAGLIMQQLTRNRFVEPTT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  81 TGTVESASLGLLLIMMFAPGMPVLGKMVIATIFAMAGSLLFIFLLCQIPLKSTLIVPLTGIMLGYVISALTNTIADYETL 160
Cdd:COG4606   81 AGTMESAKLGILVALLLFPGASLLGKMLVAFVFALAGTLLFLAILRRIPFKDALLVPLVGLMLGGVISAITTFFAYRFDL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 161 LPSLQAYLFGSFAMVLEGRYELLWLSLPVCILAYCFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVG 240
Cdd:COG4606  161 LQSLSSWLQGDFSGVLRGRYELLWLSAPLAVLAYLYADRFTIAGMGEDFATNLGLNYRRVVNLGLVIVALITAVVVVTVG 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754290365 241 RIAFVGLIIPNLVSNIMGDNMRYSAPWIAISGAGLVLICDILGRILHHGAEIPIGTMMGVIGSFIFIMLLLRWRKRLG 318
Cdd:COG4606  241 SIPFLGLIVPNIVSLYMGDNLRRTLPWVALLGAGFVLACDILGRLIIYPYEIPIGTVVGVVGSAIFLYLLLRRRRRAA 318
 
Name Accession Description Interval E-value
CeuB COG4606
ABC-type enterochelin transport system, permease component [Inorganic ion transport and ...
 1-318 1.76e-142

ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443656  Cd Length: 318  Bit Score: 404.50  E-value: 1.76e-142
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365   1 MKNYWIAIIAIILLSILSIFVGYSDITLSNLLLKDSTGWLLFWQTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPST 80
Cdd:COG4606    1 MKKLRLLILLLLVLSILSLFIGVSDVSLSDLLSLDPEALQILLISRLPRTLAILLAGASLSVAGLIMQQLTRNRFVEPTT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  81 TGTVESASLGLLLIMMFAPGMPVLGKMVIATIFAMAGSLLFIFLLCQIPLKSTLIVPLTGIMLGYVISALTNTIADYETL 160
Cdd:COG4606   81 AGTMESAKLGILVALLLFPGASLLGKMLVAFVFALAGTLLFLAILRRIPFKDALLVPLVGLMLGGVISAITTFFAYRFDL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 161 LPSLQAYLFGSFAMVLEGRYELLWLSLPVCILAYCFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVG 240
Cdd:COG4606  161 LQSLSSWLQGDFSGVLRGRYELLWLSAPLAVLAYLYADRFTIAGMGEDFATNLGLNYRRVVNLGLVIVALITAVVVVTVG 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754290365 241 RIAFVGLIIPNLVSNIMGDNMRYSAPWIAISGAGLVLICDILGRILHHGAEIPIGTMMGVIGSFIFIMLLLRWRKRLG 318
Cdd:COG4606  241 SIPFLGLIVPNIVSLYMGDNLRRTLPWVALLGAGFVLACDILGRLIIYPYEIPIGTVVGVVGSAIFLYLLLRRRRRAA 318
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 20-312 7.40e-55

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 180.80  E-value: 7.40e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365   20 FVGYSDITLSNLL-----LKDSTGWLLFWQTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLI 94
Cdd:pfam01032  11 FIGAVKISPSDVFsallgGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGAALGAVLA 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365   95 MMFAPGMPVLGKMVIATIFAMAGSLLFIFLLCQIPLKSTLIVPLTGIMLGYVISALTNTIADY--ETLLPSLQAYLFGSF 172
Cdd:pfam01032  91 ILLGGSLSLFALPLAAFIGALLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTSLLLLLlnPEALQSILFWLMGSL 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  173 A-MVLEGRYELLWLSLPVCILAYCFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPN 251
Cdd:pfam01032 171 SgANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGFVGLIVPH 250

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754290365  252 LVSNIMGDNMRYSAPWIAISGAGLVLICDILGRILHHGAEIPIGTMMGVIGSFIFIMLLLR 312
Cdd:pfam01032 251 IARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 50-310 7.73e-37

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 132.68  E-value: 7.73e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  50 TAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLIMMFAPGMPVLGKMVIATIFAMAGSLLFIFLLCQIP 129
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 130 LKsTLIVPLTGIMLGYVISALTNTIADY-ETLLPSLQAYLFGSFAMV-LEGRYELLWLSLPVCILAYCFADRFTVASLGE 207
Cdd:cd06550   81 LS-PSKLILIGIVLSAFFSAGVILISLLsDDSLQDLNIWLFGSILGVtWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 208 DLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPNLVSNIMGDNMRYSAPWIAISGAGLVLICDILGRILh 287
Cdd:cd06550  160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTL- 238

                        250       260
                 ....*....|....*....|...
gi 754290365 288 HGAEIPIGTMMGVIGSFIFIMLL 310
Cdd:cd06550  239 LPSELPVGPVTALLGAPYFLYLL 261
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 35-312 1.40e-32

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 123.14  E-value: 1.40e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  35 DSTGWLLFWQTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLIMMFAPGMPVLGKMVIAtifA 114
Cdd:PRK03784  47 SPRGELFVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPPWALSLC---A 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 115 MAGSLLFIFLLCQIPLK---STLIVPLTGIMLGYVISALTnTIADY---ETLLPSLQAYLFGSFAMVlEGRYELLWLSL- 187
Cdd:PRK03784 124 IAGALLITLILLRFARRhrlSTSRLLLAGVALGIICSALM-TWAVYfstSLDLRQLMYWMMGGFGGV-DWRQSWLMLALl 201

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 188 PVCILAYCFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPNLVSNIMGDNMRYSAPW 267
Cdd:PRK03784 202 PVLIWLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPG 281

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 754290365 268 IAISGAGLVLICDILGRILHHGAEIPIGTMMGVIGSFIFIMLLLR 312
Cdd:PRK03784 282 CALAGASLLLLADIVARLALASAELPIGVVTATLGAPVFIWLLLR 326
 
Name Accession Description Interval E-value
CeuB COG4606
ABC-type enterochelin transport system, permease component [Inorganic ion transport and ...
 1-318 1.76e-142

ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443656  Cd Length: 318  Bit Score: 404.50  E-value: 1.76e-142
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365   1 MKNYWIAIIAIILLSILSIFVGYSDITLSNLLLKDSTGWLLFWQTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPST 80
Cdd:COG4606    1 MKKLRLLILLLLVLSILSLFIGVSDVSLSDLLSLDPEALQILLISRLPRTLAILLAGASLSVAGLIMQQLTRNRFVEPTT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  81 TGTVESASLGLLLIMMFAPGMPVLGKMVIATIFAMAGSLLFIFLLCQIPLKSTLIVPLTGIMLGYVISALTNTIADYETL 160
Cdd:COG4606   81 AGTMESAKLGILVALLLFPGASLLGKMLVAFVFALAGTLLFLAILRRIPFKDALLVPLVGLMLGGVISAITTFFAYRFDL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 161 LPSLQAYLFGSFAMVLEGRYELLWLSLPVCILAYCFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVG 240
Cdd:COG4606  161 LQSLSSWLQGDFSGVLRGRYELLWLSAPLAVLAYLYADRFTIAGMGEDFATNLGLNYRRVVNLGLVIVALITAVVVVTVG 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754290365 241 RIAFVGLIIPNLVSNIMGDNMRYSAPWIAISGAGLVLICDILGRILHHGAEIPIGTMMGVIGSFIFIMLLLRWRKRLG 318
Cdd:COG4606  241 SIPFLGLIVPNIVSLYMGDNLRRTLPWVALLGAGFVLACDILGRLIIYPYEIPIGTVVGVVGSAIFLYLLLRRRRRAA 318
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 20-312 7.40e-55

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 180.80  E-value: 7.40e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365   20 FVGYSDITLSNLL-----LKDSTGWLLFWQTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLI 94
Cdd:pfam01032  11 FIGAVKISPSDVFsallgGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGAALGAVLA 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365   95 MMFAPGMPVLGKMVIATIFAMAGSLLFIFLLCQIPLKSTLIVPLTGIMLGYVISALTNTIADY--ETLLPSLQAYLFGSF 172
Cdd:pfam01032  91 ILLGGSLSLFALPLAAFIGALLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTSLLLLLlnPEALQSILFWLMGSL 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  173 A-MVLEGRYELLWLSLPVCILAYCFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPN 251
Cdd:pfam01032 171 SgANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGFVGLIVPH 250

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754290365  252 LVSNIMGDNMRYSAPWIAISGAGLVLICDILGRILHHGAEIPIGTMMGVIGSFIFIMLLLR 312
Cdd:pfam01032 251 IARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 20-314 1.22e-49

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 167.17  E-value: 1.22e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  20 FVGYSDITLSNLLL------KDSTGWLLFWQTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLL 93
Cdd:COG0609    3 SLGAVPISLSDVLRallgpdGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGAVL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  94 IMMFAPGMPVLGKMVIATIFAMAGSLLFIFLLCQIPLKSTLIVPLTGIMLGYVISALTN---TIADyETLLPSLQAYLFG 170
Cdd:COG0609   83 AIVLGGGLSALGLPLAAFLGALLAALLVYLLARRGGGLSPLRLVLAGVAVSALFSALTSlllLLAD-PEQLRSIVFWLMG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 171 SFAMVlegRYELLWLSLPV----CILAYCFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVG 246
Cdd:COG0609  162 SLAGA---SWDDVLLLLPVlligLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVG 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754290365 247 LIIPNLVSNIMGDNMRYSAPWIAISGAGLVLICDILGRILHHGAEIPIGTMMGVIGSFIFIMLLLRWR 314
Cdd:COG0609  239 LVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 35-315 7.90e-42

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 147.31  E-value: 7.90e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  35 DSTGWLLFWQTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLIMMFAPGMPVLGKMVIAtifA 114
Cdd:COG4139   44 SEAWQLFVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPLAEPGLLGISNGAGVGLVLVVLLGGGLLPPWLLSLA---A 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 115 MAGSLLFIFLLCQIP--LKSTLIVPLTGIMLGYVISALTnTIADYETLLPSLQAYL---FGSFAMVLEGRYELLWLSLPV 189
Cdd:COG4139  121 IAGALLVTLLLLAFArrRLSNARLLLIGVALGIICSAIM-TWAVYFSSSLDLRQLMywmMGSFGGVDWRQLWLLLALLPV 199

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 190 CILAYCFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPNLVSNIMGDNMRYSAPWIA 269
Cdd:COG4139  200 LLWLCLQGKPLNLLLLGENQARQLGLSVHRWRNLLVLATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACA 279

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 754290365 270 ISGAGLVLICDILGRILHHGAEIPIGTMMGVIGSFIFIMLLLRWRK 315
Cdd:COG4139  280 LAGAALLLLADIIARLALSSAELPIGVVTATLGAPVFIWLLLRRRK 325
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 50-310 7.73e-37

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 132.68  E-value: 7.73e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  50 TAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLIMMFAPGMPVLGKMVIATIFAMAGSLLFIFLLCQIP 129
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 130 LKsTLIVPLTGIMLGYVISALTNTIADY-ETLLPSLQAYLFGSFAMV-LEGRYELLWLSLPVCILAYCFADRFTVASLGE 207
Cdd:cd06550   81 LS-PSKLILIGIVLSAFFSAGVILISLLsDDSLQDLNIWLFGSILGVtWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 208 DLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPNLVSNIMGDNMRYSAPWIAISGAGLVLICDILGRILh 287
Cdd:cd06550  160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTL- 238

                        250       260
                 ....*....|....*....|...
gi 754290365 288 HGAEIPIGTMMGVIGSFIFIMLL 310
Cdd:cd06550  239 LPSELPVGPVTALLGAPYFLYLL 261
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 35-312 1.40e-32

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 123.14  E-value: 1.40e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  35 DSTGWLLFWQTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLIMMFAPGMPVLGKMVIAtifA 114
Cdd:PRK03784  47 SPRGELFVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPPWALSLC---A 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 115 MAGSLLFIFLLCQIPLK---STLIVPLTGIMLGYVISALTnTIADY---ETLLPSLQAYLFGSFAMVlEGRYELLWLSL- 187
Cdd:PRK03784 124 IAGALLITLILLRFARRhrlSTSRLLLAGVALGIICSALM-TWAVYfstSLDLRQLMYWMMGGFGGV-DWRQSWLMLALl 201

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 188 PVCILAYCFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPNLVSNIMGDNMRYSAPW 267
Cdd:PRK03784 202 PVLIWLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPG 281

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 754290365 268 IAISGAGLVLICDILGRILHHGAEIPIGTMMGVIGSFIFIMLLLR 312
Cdd:PRK03784 282 CALAGASLLLLADIVARLALASAELPIGVVTATLGAPVFIWLLLR 326
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
40-318 1.96e-29

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 118.02  E-value: 1.96e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  40 LLFWQTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLIMMFAPGMPVLGkmviATIFAMAGSL 119
Cdd:PRK10577  56 LLLHYSRLPRLAIALLVGAALGLAGALLQQVLRNPLASPTTLGVAAGAQLALVLATLFAPALLALA----SQLAAFAGGL 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 120 L---FIFLLCQIPLKSTLIVPLTGIMLGYVISALTNTI-ADYETLLPSLqaYLFGSFAMVLEGRYELLWL---SLPVCIL 192
Cdd:PRK10577 132 LaaaLVFALAGGKRLSPLRLVLAGMVVSLYLGALTTLLlLFNEQYLQGL--FLWGAGSLAQNDWSGVQRLlprLLVGLLL 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 193 AYCFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPNLVSNIMGDNMRYSAPWIAISG 272
Cdd:PRK10577 210 LLLLARPLTLLGLGDDVARSLGLAVSLTRLAALALAVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIG 289

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 754290365 273 AGLVLICDILGRIL--HHGAEIPIGTMMGVIGSFIFIMLLLRWRKRLG 318
Cdd:PRK10577 290 ALLLLLTDQLVRLLagVGGELLPTGAVTALIGAPLLLWLLPRLRSAQS 337
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
39-316 6.06e-28

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 113.78  E-value: 6.06e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  39 WLLFWQTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLIMMFAPGMPVLGKMVIATIFAMAgS 118
Cdd:PRK10577 390 LDALLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAGFGWLLAAALLGALA-A 468

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 119 LLFIFLLCQIPLKSTLIVPLTGIMLGYVISALTN-TIADYETLLPSLQAYLFGSFAMVLegrYELLWLSLPVCIL----A 193
Cdd:PRK10577 469 LALILLLARRGGFAPERLLLTGIALSALFTALIQlLLASGDPRAAQLLTWLSGSTYGVT---WAQALPLLIVAVLllalA 545

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 194 YCFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPNLVSNIMGDNMRYSAPWIAISGA 273
Cdd:PRK10577 546 LLLRRWLDLLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGA 625

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 754290365 274 GLVLICDILGRILHHGAEIPIGTMMGVIGSFIFIMLLLRWRKR 316
Cdd:PRK10577 626 LLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRRSRRR 668
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
44-314 1.15e-26

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 107.05  E-value: 1.15e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  44 QTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLIMMFAPGMPVLGKMVIATIFAMAGsLLFIF 123
Cdd:PRK09777  49 EYRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPDILGVNHAASLASVGALLLFPSLPVMWLPLLAFIGGMAG-LILLK 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 124 LLCQipLKSTLIVPLTGIMLgyviSALTNTIADYETLLPSLQA-----YLFGSfamvLEGR-YELLWLSLPVCI----LA 193
Cdd:PRK09777 128 MLAG--THQPMKLALTGVAL----SALWASLTDYLMLSRPQDInnallWLTGS----LWGRdWSFVKVALPWLIlllpLS 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 194 YCFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPNLVSNIMGDNMRYSAPWIAISGA 273
Cdd:PRK09777 198 LSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVALTATGVAACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGA 277

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 754290365 274 GLVLICDILGRILHHGAEIPIGTMMGVIGSFIFIMLLLRWR 314
Cdd:PRK09777 278 LLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLLVRMR 318
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
44-312 6.42e-24

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 99.38  E-value: 6.42e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  44 QTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLIMMFAPgMPVLGkMVIATIFAMAGSL--LF 121
Cdd:PRK11228  49 NLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTSALSP-TPFAG-YSLAFIAACGGGLswLL 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 122 IFLLC----QIPLKSTLIvpLTGIMLGYVISALTN-TIADYETLLPSLQAYLFGSFAMVLEGRYELLW----LSLPVCIL 192
Cdd:PRK11228 127 VMTAGggwrHTHDRNRLI--LAGIALSALCMALTRiTLLLAEDHAYGIFYWLAGGVSHARWQEVWQLLpfvvTAVPVVLL 204

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 193 aycFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPNLVSNIMGDNMRYSAPWIAISG 272
Cdd:PRK11228 205 ---LANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFWIGYDQRNVLPMSMLLG 281

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 754290365 273 AGLVLICDILGRILHHGAEIPIGTMMGVIGSFIFIMLLLR 312
Cdd:PRK11228 282 ATLMLLADLLARALAFPGELPAGAVLALIGAPCFVWLARR 321
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
44-312 2.35e-21

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 92.46  E-value: 2.35e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  44 QTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLIMMFAPGMPVLGKMVIATIFAMAGSLLFIF 123
Cdd:PRK10441  58 DARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAF 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 124 LLCQIPLK-STLIVPLTGIMLGYVISALTNTIAdyeTLLPSLQAYLFGSFAMVLEGR--YELLWLSLPVCI---LAYCFA 197
Cdd:PRK10441 138 TGSQGGGQlSPVRLTLAGVALAAVLEGLTSGIA---LLNPDVYDQLRFWQAGSLDIRnlHTLKVVLIPVLIagaTALLLS 214

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 198 DRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPNLVSNIMGDNMRYSAPWIAISGAGLVL 277
Cdd:PRK10441 215 RALNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLL 294

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 754290365 278 ICDILGRILHHGaEIPIGTMMGVIGSFIFIMLLLR 312
Cdd:PRK10441 295 FADIIGRLLVPG-ELRVSVVSAFIGAPVLIFLVRR 328
btuC PRK09535
cobalamin ABC transporter permease BtuC;
44-312 1.33e-15

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 76.33  E-value: 1.33e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  44 QTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLIMMFAPGMPVLgkmviATIFAMAGSLLFIF 123
Cdd:PRK09535  93 QIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLAVPFG-----LQAAAFAGALVAAF 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 124 LLCQIPLK------STLIvpLTGI----MLGYVIS-ALTNTIADYETLLPSLQAYLFGSfamvlegRYELLWLSLPVCIL 192
Cdd:PRK09535 168 GVYAIATEngrtpvATLL--LAGVavqtFLGAVISyLLLHSGESLRRAVYWLMGHLHGS-------TWSDVEVALPVVVV 238

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 193 A----YCFADRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPNLVSNIMGDNMRYSAPWI 268
Cdd:PRK09535 239 GfvvlLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRILLPTS 318

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 754290365 269 AISGAGLVLICDILGRilHHGAEIPIGTMMGVIGSFIFIMLLLR 312
Cdd:PRK09535 319 ALAGASFLVATDTVAR--SGPAEVPVGIVTAALGAPFFLYLLRT 360
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
44-312 5.07e-10

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 59.72  E-value: 5.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365  44 QTRLPRTAAALLSGMALALSGMIMQMLVRNRFVEPSTTGTVESASLGLLLIMMfapgmpVLGKMVIATIF-AMAGSLLFI 122
Cdd:PRK10440  57 EWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMV------LFGQDLTAIALaAMAGGIVTS 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 123 FLLCQIPLKSTlIVPLTGIMLGYVISALTNTIADYETLLPSLQAYLFGSF--AMVLEG-RYELLWLSLPVCILAYCFA-- 197
Cdd:PRK10440 131 LLVWLLAWRNG-IDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTAGLwnAGSLNGlTWAKTSPSAPIIILMLIAAal 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754290365 198 --DRFTVASLGEDLTNNLGLNYRSVMFLGLFIIALITALVVCTVGRIAFVGLIIPNLVSNIMGDNmRYSAPWIAISGAGL 275
Cdd:PRK10440 210 lvRRMRLLEMGDDTACALGVSVERSRLLLMLVAVVLTAAATALAGPISFIALVAPHIARRLSGTA-RWGLTQAALCGALL 288

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 754290365 276 VLICDILGRILHHGAEIPIGTMMGVIGSFIFIMLLLR 312
Cdd:PRK10440 289 LLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQ 325
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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