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Conserved domains on  [gi|754557668|ref|WP_041951321|]
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TetR/AcrR family transcriptional regulator [Hydrogenobaculum sp. SHO]

Protein Classification

TetR/AcrR family transcriptional regulator( domain architecture ID 11442015)

TetR/AcrR family transcriptional regulator may control genes involved in one of a variety of processes including antibiotic production, osmotic stress response, efflux pump expression, and multidrug resistance

CATH:  1.10.10.60|1.10.357.10
Gene Ontology:  GO:0003700|GO:0003677|GO:0006355
PubMed:  23602932
SCOP:  4000333

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AcrR COG1309
DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];
1-102 1.08e-18

DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];


:

Pssm-ID: 440920 [Multi-domain]  Cd Length: 156  Bit Score: 78.40  E-value: 1.08e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754557668   1 MPRRTRNRILHEALKIFSNKGIRETTIKDIARAVGITEGAIYRHFDSKEQIVKSLFLNSSQEFYNHLSSALSkAQNFEEA 80
Cdd:COG1309    3 RREATRERILDAALELFAEKGYEGTSVRDIAARAGVSKGTLYRHFGSKEELLLAVLERLLEELLAALEEALA-AEDPRER 81

                         90       100
                 ....*....|....*....|..
gi 754557668  81 LKNLSEAFLNYAFTNPKAFKFI 102
Cdd:COG1309   82 LRALLRAYLEFLAENPALARLL 103
 
Name Accession Description Interval E-value
AcrR COG1309
DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];
1-102 1.08e-18

DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];


Pssm-ID: 440920 [Multi-domain]  Cd Length: 156  Bit Score: 78.40  E-value: 1.08e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754557668   1 MPRRTRNRILHEALKIFSNKGIRETTIKDIARAVGITEGAIYRHFDSKEQIVKSLFLNSSQEFYNHLSSALSkAQNFEEA 80
Cdd:COG1309    3 RREATRERILDAALELFAEKGYEGTSVRDIAARAGVSKGTLYRHFGSKEELLLAVLERLLEELLAALEEALA-AEDPRER 81

                         90       100
                 ....*....|....*....|..
gi 754557668  81 LKNLSEAFLNYAFTNPKAFKFI 102
Cdd:COG1309   82 LRALLRAYLEFLAENPALARLL 103
TetR_N pfam00440
Bacterial regulatory proteins, tetR family;
9-55 1.63e-12

Bacterial regulatory proteins, tetR family;


Pssm-ID: 425684 [Multi-domain]  Cd Length: 47  Bit Score: 59.34  E-value: 1.63e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 754557668    9 ILHEALKIFSNKGIRETTIKDIARAVGITEGAIYRHFDSKEQIVKSL 55
Cdd:pfam00440   1 ILDAARELFAERGYDATTVREIAKRAGVSKGALYRYFGSKEELLEAL 47
ScbR_bind_reg NF041196
ScbR family autoregulator-binding transcription factor;
3-51 1.13e-11

ScbR family autoregulator-binding transcription factor;


Pssm-ID: 469100 [Multi-domain]  Cd Length: 191  Bit Score: 60.69  E-value: 1.13e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 754557668   3 RRTRNRILHEALKIFSNKGIRETTIKDIARAVGITEGAIYRHFDSKEQI 51
Cdd:NF041196   5 IRTRRAILEAAAEVFDERGYAAATISDILERAGVTKGALYFHFSSKEAL 53
PRK10668 PRK10668
DNA-binding transcriptional repressor AcrR; Provisional
 5-48 9.75e-10

DNA-binding transcriptional repressor AcrR; Provisional


Pssm-ID: 182632 [Multi-domain]  Cd Length: 215  Bit Score: 55.78  E-value: 9.75e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 754557668   5 TRNRILHEALKIFSNKGIRETTIKDIARAVGITEGAIYRHFDSK 48
Cdd:PRK10668  12 TRQHILDAALRLFSQQGVSATSLADIAKAAGVTRGAIYWHFKNK 55
 
Name Accession Description Interval E-value
AcrR COG1309
DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];
1-102 1.08e-18

DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];


Pssm-ID: 440920 [Multi-domain]  Cd Length: 156  Bit Score: 78.40  E-value: 1.08e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754557668   1 MPRRTRNRILHEALKIFSNKGIRETTIKDIARAVGITEGAIYRHFDSKEQIVKSLFLNSSQEFYNHLSSALSkAQNFEEA 80
Cdd:COG1309    3 RREATRERILDAALELFAEKGYEGTSVRDIAARAGVSKGTLYRHFGSKEELLLAVLERLLEELLAALEEALA-AEDPRER 81

                         90       100
                 ....*....|....*....|..
gi 754557668  81 LKNLSEAFLNYAFTNPKAFKFI 102
Cdd:COG1309   82 LRALLRAYLEFLAENPALARLL 103
TetR_N pfam00440
Bacterial regulatory proteins, tetR family;
9-55 1.63e-12

Bacterial regulatory proteins, tetR family;


Pssm-ID: 425684 [Multi-domain]  Cd Length: 47  Bit Score: 59.34  E-value: 1.63e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 754557668    9 ILHEALKIFSNKGIRETTIKDIARAVGITEGAIYRHFDSKEQIVKSL 55
Cdd:pfam00440   1 ILDAARELFAERGYDATTVREIAKRAGVSKGALYRYFGSKEELLEAL 47
ScbR_bind_reg NF041196
ScbR family autoregulator-binding transcription factor;
3-51 1.13e-11

ScbR family autoregulator-binding transcription factor;


Pssm-ID: 469100 [Multi-domain]  Cd Length: 191  Bit Score: 60.69  E-value: 1.13e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 754557668   3 RRTRNRILHEALKIFSNKGIRETTIKDIARAVGITEGAIYRHFDSKEQI 51
Cdd:NF041196   5 IRTRRAILEAAAEVFDERGYAAATISDILERAGVTKGALYFHFSSKEAL 53
PRK10668 PRK10668
DNA-binding transcriptional repressor AcrR; Provisional
 5-48 9.75e-10

DNA-binding transcriptional repressor AcrR; Provisional


Pssm-ID: 182632 [Multi-domain]  Cd Length: 215  Bit Score: 55.78  E-value: 9.75e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 754557668   5 TRNRILHEALKIFSNKGIRETTIKDIARAVGITEGAIYRHFDSK 48
Cdd:PRK10668  12 TRQHILDAALRLFSQQGVSATSLADIAKAAGVTRGAIYWHFKNK 55
PRK09975 PRK09975
DNA-binding transcriptional regulator EnvR; Provisional
 4-51 1.65e-09

DNA-binding transcriptional regulator EnvR; Provisional


Pssm-ID: 182177 [Multi-domain]  Cd Length: 213  Bit Score: 55.13  E-value: 1.65e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 754557668   4 RTRNRILHEALKIFSNKGIRETTIKDIARAVGITEGAIYRHFDSKEQI 51
Cdd:PRK09975  11 KTRQELIETAIAQFALRGVSNTTLNDIADAANVTRGAIYWHFENKTQL 58
slmA PRK09480
division inhibitor protein; Provisional
 18-55 2.02e-04

division inhibitor protein; Provisional


Pssm-ID: 181894 [Multi-domain]  Cd Length: 194  Bit Score: 40.18  E-value: 2.02e-04
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 754557668  18 SNKGIRETTIKdIARAVGITEGAIYRHFDSKEQIVKSL 55
Cdd:PRK09480  25 SPPGERITTAK-LAARVGVSEAALYRHFPSKARMFEGL 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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