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Conserved domains on  [gi|754692813|ref|WP_042070296|]
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MULTISPECIES: nucleoside triphosphate pyrophosphatase [Aeromonas]

Protein Classification

Maf family protein( domain architecture ID 10785471)

multicopy associated filamentation (Maf) family protein is involved in septum formation and also has a role as a house-cleaning NTP pyrophosphatase

CATH:  3.90.950.10
EC:  3.6.1.-
Gene Ontology:  GO:0009117|GO:0047429|GO:0009146|GO:0000166
PubMed:  24210219
SCOP:  4000520

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 7-186 1.44e-89

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 440193  Cd Length: 189  Bit Score: 260.36  E-value: 1.44e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   7 PQLYLASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALpVLGADTIVVLGDRVLE 86
Cdd:COG0424    1 PKLILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARLPDAL-VLGADTVVVLDGRILG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  87 KPSDLLDAKDMLEALSGKVHQVMTAVALATPE-RCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFV 165
Cdd:COG0424   80 KPADAEEARAMLRRLSGRTHRVHTGVALIDPGgRLWTRVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLGAALV 159

                        170       180
                 ....*....|....*....|..
gi 754692813 166 SRMEGSYSAVVGLPLLET-DLL 186
Cdd:COG0424  160 ERIEGSYSNVVGLPLIELlELL 181
 
Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 7-186 1.44e-89

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 260.36  E-value: 1.44e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   7 PQLYLASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALpVLGADTIVVLGDRVLE 86
Cdd:COG0424    1 PKLILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARLPDAL-VLGADTVVVLDGRILG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  87 KPSDLLDAKDMLEALSGKVHQVMTAVALATPE-RCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFV 165
Cdd:COG0424   80 KPADAEEARAMLRRLSGRTHRVHTGVALIDPGgRLWTRVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLGAALV 159

                        170       180
                 ....*....|....*....|..
gi 754692813 166 SRMEGSYSAVVGLPLLET-DLL 186
Cdd:COG0424  160 ERIEGSYSNVVGLPLIELlELL 181
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 9-183 6.32e-83

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 243.15  E-value: 6.32e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   9 LYLASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALPVLGADTIVVLGDRVLEKP 88
Cdd:cd00555    1 LILASASPRRRELLEQLGIPFEVVPSDIDETPIKGESPEDYVLRLAEAKAEAVAARLPPDALVIGADTVVVLDGRILGKP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  89 SDLLDAKDMLEALSGKVHQVMTAVALATP-ERCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFVSR 167
Cdd:cd00555   81 KDREEAREMLKRLSGRTHEVYTGVALIDPgGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAGAYGIQGLGGALIER 160

                        170
                 ....*....|....*.
gi 754692813 168 MEGSYSAVVGLPLLET 183
Cdd:cd00555  161 IEGDYSNVVGLPLPEL 176
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 9-190 1.96e-77

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 229.21  E-value: 1.96e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813    9 LYLASGSPRRHELLTQLGYRFEVLRLDVPEQ-REEGEKAQDYVCRLARDKAMAGlacaptalpVLGADTIVVLgdrVLEK 87
Cdd:pfam02545   1 LILASASPRRRELLEQLGIEFEVVPSDIDETpLKEDPAPEEYVLRLARAKAEAL---------VIGADTVVVL---ILGK 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   88 PSDLLDAKDMLEALSGKVHQVMTAVALATPERCDVR---LVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKF 164
Cdd:pfam02545  69 PKDEEEARAMLKRLSGRTHEVYTGVALINPGGGTGGvsfVETTRVTFRPLSDEEIEAYVATGEPLDKAGAYGIQGLGAAL 148

                         170       180
                  ....*....|....*....|....*.
gi 754692813  165 VSRMEGSYSAVVGLPLLETDLLIKHH 190
Cdd:pfam02545 149 VERIEGDYSNVVGLPLIELLRLLREL 174
PRK04694 PRK04694
Maf-like protein; Reviewed
 9-187 5.03e-64

Maf-like protein; Reviewed


Pssm-ID: 179873  Cd Length: 190  Bit Score: 195.95  E-value: 5.03e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   9 LYLASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALP---VLGADTIVVLGDRVL 85
Cdd:PRK04694   2 LYLASRSPRRRELLQRLDVPFQTLQLDVPEVRAADESPDHYVQRVALEKAHAGLALVQAADAdaiVLGSDTEVVLGERVF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  86 EKPSDLLDAKDMLEALSGKVHQVMTAVALATPERCDVR-LVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKF 164
Cdd:PRK04694  82 GKPVDVDDAIAMLRALSGRTHQVLTAVVLVCAQRAPAQaLVVSEVTFDLLDDAQIAAYAASGEPMGKAGAYAIQGRAERF 161

                        170       180
                 ....*....|....*....|...
gi 754692813 165 VSRMEGSYSAVVGLPLLETDLLI 187
Cdd:PRK04694 162 IRHLSGSYSGVMGLPLYQTSQLL 184
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 7-183 4.91e-58

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 180.29  E-value: 4.91e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813    7 PQLYLASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTAlPVLGADTIVVLGDRVLE 86
Cdd:TIGR00172   3 KELILASQSPRRKELLEELGISFEQIVSEFDEKSLKTTSPRELVYRLAKEKAQAVAELLADA-LIIGADTVVILDGEIYG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   87 KPSDLLDAKDMLEALSGKVHQVMTAVALATPERCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFVS 166
Cdd:TIGR00172  82 KPKDKEEAAEFLRKLSGQEHEVYTAVALIDSVHLLTFLDVTKVHFRALDPEEIEKYVESGEPLEKAGAFGIEGFGAPLIK 161

                         170
                  ....*....|....*..
gi 754692813  167 RMEGSYSAVVGLPLLET 183
Cdd:TIGR00172 162 KIDGDYSNVVGLPLEKL 178
 
Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 7-186 1.44e-89

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 260.36  E-value: 1.44e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   7 PQLYLASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALpVLGADTIVVLGDRVLE 86
Cdd:COG0424    1 PKLILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARLPDAL-VLGADTVVVLDGRILG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  87 KPSDLLDAKDMLEALSGKVHQVMTAVALATPE-RCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFV 165
Cdd:COG0424   80 KPADAEEARAMLRRLSGRTHRVHTGVALIDPGgRLWTRVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLGAALV 159

                        170       180
                 ....*....|....*....|..
gi 754692813 166 SRMEGSYSAVVGLPLLET-DLL 186
Cdd:COG0424  160 ERIEGSYSNVVGLPLIELlELL 181
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 9-183 6.32e-83

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 243.15  E-value: 6.32e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   9 LYLASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALPVLGADTIVVLGDRVLEKP 88
Cdd:cd00555    1 LILASASPRRRELLEQLGIPFEVVPSDIDETPIKGESPEDYVLRLAEAKAEAVAARLPPDALVIGADTVVVLDGRILGKP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  89 SDLLDAKDMLEALSGKVHQVMTAVALATP-ERCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFVSR 167
Cdd:cd00555   81 KDREEAREMLKRLSGRTHEVYTGVALIDPgGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAGAYGIQGLGGALIER 160

                        170
                 ....*....|....*.
gi 754692813 168 MEGSYSAVVGLPLLET 183
Cdd:cd00555  161 IEGDYSNVVGLPLPEL 176
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 9-190 1.96e-77

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 229.21  E-value: 1.96e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813    9 LYLASGSPRRHELLTQLGYRFEVLRLDVPEQ-REEGEKAQDYVCRLARDKAMAGlacaptalpVLGADTIVVLgdrVLEK 87
Cdd:pfam02545   1 LILASASPRRRELLEQLGIEFEVVPSDIDETpLKEDPAPEEYVLRLARAKAEAL---------VIGADTVVVL---ILGK 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   88 PSDLLDAKDMLEALSGKVHQVMTAVALATPERCDVR---LVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKF 164
Cdd:pfam02545  69 PKDEEEARAMLKRLSGRTHEVYTGVALINPGGGTGGvsfVETTRVTFRPLSDEEIEAYVATGEPLDKAGAYGIQGLGAAL 148

                         170       180
                  ....*....|....*....|....*.
gi 754692813  165 VSRMEGSYSAVVGLPLLETDLLIKHH 190
Cdd:pfam02545 149 VERIEGDYSNVVGLPLIELLRLLREL 174
PRK04694 PRK04694
Maf-like protein; Reviewed
 9-187 5.03e-64

Maf-like protein; Reviewed


Pssm-ID: 179873  Cd Length: 190  Bit Score: 195.95  E-value: 5.03e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   9 LYLASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALP---VLGADTIVVLGDRVL 85
Cdd:PRK04694   2 LYLASRSPRRRELLQRLDVPFQTLQLDVPEVRAADESPDHYVQRVALEKAHAGLALVQAADAdaiVLGSDTEVVLGERVF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  86 EKPSDLLDAKDMLEALSGKVHQVMTAVALATPERCDVR-LVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKF 164
Cdd:PRK04694  82 GKPVDVDDAIAMLRALSGRTHQVLTAVVLVCAQRAPAQaLVVSEVTFDLLDDAQIAAYAASGEPMGKAGAYAIQGRAERF 161

                        170       180
                 ....*....|....*....|...
gi 754692813 165 VSRMEGSYSAVVGLPLLETDLLI 187
Cdd:PRK04694 162 IRHLSGSYSGVMGLPLYQTSQLL 184
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 7-183 4.91e-58

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 180.29  E-value: 4.91e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813    7 PQLYLASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTAlPVLGADTIVVLGDRVLE 86
Cdd:TIGR00172   3 KELILASQSPRRKELLEELGISFEQIVSEFDEKSLKTTSPRELVYRLAKEKAQAVAELLADA-LIIGADTVVILDGEIYG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   87 KPSDLLDAKDMLEALSGKVHQVMTAVALATPERCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFVS 166
Cdd:TIGR00172  82 KPKDKEEAAEFLRKLSGQEHEVYTAVALIDSVHLLTFLDVTKVHFRALDPEEIEKYVESGEPLEKAGAFGIEGFGAPLIK 161

                         170
                  ....*....|....*..
gi 754692813  167 RMEGSYSAVVGLPLLET 183
Cdd:TIGR00172 162 KIDGDYSNVVGLPLEKL 178
PRK14368 PRK14368
Maf-like protein; Provisional
 11-182 2.10e-54

Maf-like protein; Provisional


Pssm-ID: 237693  Cd Length: 193  Bit Score: 171.50  E-value: 2.10e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  11 LASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALpVLGADTIVVLGDRVLEKPSD 90
Cdd:PRK14368   9 LASASPRRSELLASAGIEFDVVPADIPEEPLPGEEPVDHVLRLAREKARAAAALAEGRF-FIGADTIVVCDGEIMGKPKD 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  91 LLDAKDMLEALSGKVHQVMTAVALATPER--CDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFVSRM 168
Cdd:PRK14368  88 EADAVRMLKKLSGVPHEVITGFAVYDRERdgCVTKAVRTKVFFKPLRDEEIRDYIATGCPMDKAGAYAIQGGAAHMVRKI 167

                        170
                 ....*....|....
gi 754692813 169 EGSYSAVVGLPLLE 182
Cdd:PRK14368 168 DGSYTNVVGLPLCE 181
PRK00648 PRK00648
Maf-like protein; Reviewed
 6-194 5.95e-54

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 170.09  E-value: 5.95e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   6 EPQLYLASGSPRRHELLTQLGYRFEVLRL-DVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALPVLGADTIVVLGDRV 84
Cdd:PRK00648   2 KYKIILASSSPRRKEILEGFRIPFEVVPSpFVEESYPYSLDPEEITLELARLKAEAVRSDLFPDELIITADTIVWYDGKV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  85 LEKPSDLLDAKDMLEALSGKVHQVMTAVALATPERCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKF 164
Cdd:PRK00648  82 LGKPKDEEEAVEMLRTLSGKTHEVITGVCLLHNGKLLSGSETTQVTFRELSDEEIEYYIDTYKPLDKAGAYGIQEWGGLI 161

                        170       180       190
                 ....*....|....*....|....*....|
gi 754692813 165 VSRMEGSYSAVVGLPLletdLLIKHHLEQL 194
Cdd:PRK00648 162 VKKIEGSYYNVMGLPI----QTLYEELKEL 187
PRK14364 PRK14364
Maf-like protein; Provisional
 11-188 4.09e-53

Maf-like protein; Provisional


Pssm-ID: 184648  Cd Length: 181  Bit Score: 167.87  E-value: 4.09e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  11 LASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALpVLGADTIVVLGDRVLEKPSD 90
Cdd:PRK14364   1 LASSSPRRRELLQQLGLNFEIYSPDIDESVHEGELVHQYVERLAREKAQAVLNIFPDSV-IIAADTSLGLDGQIIGKPDS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  91 LLDAKDMLEALSGKVHQVMTAVALATPERCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFVSRMEG 170
Cdd:PRK14364  80 KQHAFDIWKQLSGRWHDVFSGICIATQQQILSQVVQTQVEFASLTTQDMEDYWATGEPVGKAGAYAIQGIASQYIPKIQG 159

                        170
                 ....*....|....*...
gi 754692813 171 SYSAVVGLPLLETDLLIK 188
Cdd:PRK14364 160 SYSNVVGLPLYEFSQLFK 177
PRK01441 PRK01441
Maf-like protein; Reviewed
 7-187 5.38e-48

Maf-like protein; Reviewed


Pssm-ID: 167232  Cd Length: 207  Bit Score: 155.64  E-value: 5.38e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   7 PQLYLASGSPRRHELLTQLGYRFEVLR-LDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALP-----VLGADTIVVL 80
Cdd:PRK01441   5 PKLVLASGSPRRVELLNQAGIEPDRLMpADIDETPKRAEHPRSLARRLSREKAEAALEALQGDDDwrgayILAADTVVAV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  81 GDRVLEKPSDLLDAKDMLEALSGKVHQVMTAVALATPER-CDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQG 159
Cdd:PRK01441  85 GRRILPKAELVDEASQCLRLLSGRNHRVYTGVCLVTPDGkLRQKLVETRVRFKRLSREDIEAYLASGEWRGKAGGYAIQG 164

                        170       180
                 ....*....|....*....|....*...
gi 754692813 160 IAGKFVSRMEGSYSAVVGLPLLETDLLI 187
Cdd:PRK01441 165 IAGSFVVKLVGSYTNVVGLPLYETVSLL 192
PRK14367 PRK14367
Maf-like protein; Provisional
 9-183 1.74e-47

Maf-like protein; Provisional


Pssm-ID: 237692  Cd Length: 202  Bit Score: 154.07  E-value: 1.74e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   9 LYLASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLA--CAPTA----LPVLGADTIVVLGD 82
Cdd:PRK14367   4 LYLGSNSPRRMEILTQLGYRVVKLPAGIDETVKAGETPARYVQRMAEEKNRTALTlfCETNGtmpdFPLITADTCVVSDG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  83 RVLEKPSDLLDAKDMLEALSGKVHQVMTAVALATPERCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAG 162
Cdd:PRK14367  84 IILGKPRSQAEAIEFLNRLSGKQHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGIGG 163

                        170       180
                 ....*....|....*....|.
gi 754692813 163 KFVSRMEGSYSAVVGLPLLET 183
Cdd:PRK14367 164 IFIQSIEGSFSGIMGLPVYET 184
PRK14362 PRK14362
Maf-like protein; Provisional
 9-189 3.93e-45

Maf-like protein; Provisional


Pssm-ID: 172838  Cd Length: 207  Bit Score: 148.47  E-value: 3.93e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   9 LYLASGSPRRHELLTQLGYRFEVlrlDVPEQRE----EGEKAQDYVCRLARDKAMAGLACAPTALpVLGADTIVVLGDRV 84
Cdd:PRK14362  14 VVLASGSPRRREFLEQMGLPFEV---ILPGAAEpspiEGEQPEAYARRAAEAKARAVAADHAGRL-VIAADTVVALDGMI 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  85 LEKPSDLLDAKDMLEALSGKVHQVMTAVALATPE-RCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGK 163
Cdd:PRK14362  90 LGKPADRADALSMLRRLAGRTHEVVSACCVVLPDgGREVFHAITRVTMWDWPEAALAAYVATGEPSDKAGAYGIQGIGAF 169

                        170       180
                 ....*....|....*....|....*..
gi 754692813 164 FVSRMEGSYSAVVGLPLLE-TDLLIKH 189
Cdd:PRK14362 170 LVRSIEGSWSNVVGLPVAElTALLLRR 196
PRK00078 PRK00078
Maf-like protein; Reviewed
 11-180 1.09e-44

Maf-like protein; Reviewed


Pssm-ID: 234618  Cd Length: 192  Bit Score: 146.80  E-value: 1.09e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  11 LASGSPRRHELLTQLGYRFEVLRLDVPEQREEGE-KAQDYVCRLARDKAMAgLACAPTALP--VLGADTIVVLGDRVLEK 87
Cdd:PRK00078   5 LASASERRQELLKRILEDFQVIVSDFDESSVPFKgNIESYVMNLAEGKARS-VSKKLDQESsiVIGCDTIVAFNGKVLGK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  88 PSDLLDAKDMLEALSGKVHQVMTAVAL--ATPERCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFV 165
Cdd:PRK00078  84 PKDEEDAFEMLKALSGNEHEVYSGIAIldTKSNKIIKDFVCTEVKFSKLTDRQIRKYINTGEPMDKAGAYGIQGKGGVFV 163

                        170
                 ....*....|....*
gi 754692813 166 SRMEGSYSAVVGLPL 180
Cdd:PRK00078 164 EEINGCYYNVVGLPL 178
PRK14366 PRK14366
Maf-like protein; Provisional
 9-183 8.65e-44

Maf-like protein; Provisional


Pssm-ID: 237691  Cd Length: 195  Bit Score: 144.56  E-value: 8.65e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   9 LYLASGSPRRHELLTQLGYR-FEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALpVLGADTIVVLGDRVLEK 87
Cdd:PRK14366   7 LILASSSKQRLALLEQIGVVpGEIVSPDIDESPLKKELPKDYSIRMAKEKAEKVQSLRPDKF-VLGADTVVCCGRRILLK 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  88 PSDLLDAKDMLEALSGKVHQVMTAVALATPE-RCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFVS 166
Cdd:PRK14366  86 AETEEQAEEYLELLSGRRHRVYTSVCLYTPGgKLHIRSVVTVVKFKRLSKQEIKYYIASGEWKGKAGGCNIQGLAGKFVL 165

                        170
                 ....*....|....*..
gi 754692813 167 RMEGSYSAVVGLPLLET 183
Cdd:PRK14366 166 SINGSYSSIIGLPLHET 182
PRK14361 PRK14361
Maf-like protein; Provisional
 11-180 6.01e-42

Maf-like protein; Provisional


Pssm-ID: 172837  Cd Length: 187  Bit Score: 139.68  E-value: 6.01e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  11 LASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQdYVCRLARDKAMAGLACAPTALpVLGADTIVVLGDRVLEKPSD 90
Cdd:PRK14361   3 LASGSPRRRELLENLGVPFQVVVSGEAEDSTETDPAR-LAAELALLKARAVARLHPDAV-VIAADTVVALGGVLLAKPAD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  91 LLDAKDMLEALSGKVHQVMTAVALATPERCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFVSRMEG 170
Cdd:PRK14361  81 EAENEAFLRVLSGRTHQVYTGVAVLSRGTEQVGVERTDVTFRALTAAEISFYARSGEGLDKAGGYGIQGVGMALVSRVEG 160

                        170
                 ....*....|
gi 754692813 171 SYSAVVGLPL 180
Cdd:PRK14361 161 DYSNVVGFPL 170
PRK14363 PRK14363
Maf-like protein; Provisional
 8-180 1.59e-39

Maf-like protein; Provisional


Pssm-ID: 184647  Cd Length: 204  Bit Score: 133.87  E-value: 1.59e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   8 QLYLASGSPRRHELLTQLGYRFEVLRLDVPEqrEEGEKAQDYVCRLARDKAMAGLACAPTA-LPVLGADTIVVLGDRVLE 86
Cdd:PRK14363   2 RIILASSSPRRRQLMELLGIEFEVEKPDVEE--EFLESPEETVRELSLRKAEWVFKKRKEEeILVIGSDTVVVLDGNILG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  87 KPSDLLDAKDMLEALSGKVHQVMTAVALATPERCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFVS 166
Cdd:PRK14363  80 KPESLEEAKGMLKKLSGRWHVVYTGVAFVSSETKDVIVSSTKVRFRELPESVIDYYVEKYRPLDKAGAYGIQDFAAVFVE 159

                        170
                 ....*....|....
gi 754692813 167 RMEGSYSAVVGLPL 180
Cdd:PRK14363 160 KIEGDFFTVVGFPL 173
PRK14365 PRK14365
Maf-like protein; Provisional
 8-180 4.89e-35

Maf-like protein; Provisional


Pssm-ID: 237690  Cd Length: 197  Bit Score: 122.24  E-value: 4.89e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   8 QLYLASGSPRRHELLTQL-GYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALpVLGADTIVVLGDRVLE 86
Cdd:PRK14365   3 RIILASASPRRKELLKQLiGDNFLVYPSSYEEPPQPGLDPEELLLKHSLEKARDVAKHFDSGI-IISADTSVFCNGEVLG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  87 KPSDLLDAKDMLEALSGKVHQVMTAVALATPE--RCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKF 164
Cdd:PRK14365  82 KPASPENAEEMLEKLSGRKFLVITGLTVLDLDsgKEISEIESTDVWMTELSREQILAYVRTGEPLDKAGAFAIQGKGAVL 161

                        170
                 ....*....|....*.
gi 754692813 165 VSRMEGSYSAVVGLPL 180
Cdd:PRK14365 162 VEKIEGDFFNVVGLPL 177
Maf_Ham1 cd00985
Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum ...
 9-134 1.43e-33

Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, such as hypoxanthine/xanthine NTP, but not standard nucleotides.


Pssm-ID: 238485  Cd Length: 131  Bit Score: 116.06  E-value: 1.43e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   9 LYLASGSPRRHELLTQLG-YRFEVLRLDVPEQREEGEkAQDYVCRLARDKAMAGLACAPTAlPVLGADTIVVLGDRVLEK 87
Cdd:cd00985    1 LILASGSPRRLEELKQIGgIEFEVLPSDIDETGLKGE-PEDTVEELALLKARAVAERLPDA-PVIADDTGLVVDGRPGGK 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 754692813  88 PSDLLDAKDMLEALSGKVHQVMTAVALATPE-RCDVRLVTTNV--AFRKL 134
Cdd:cd00985   79 PARFAEALEMLRGLSGRTAEFVTAVALVDPDgKIITFEGETEGkiALRKL 128
PRK04056 PRK04056
septum formation inhibitor Maf;
8-178 1.00e-24

septum formation inhibitor Maf;


Pssm-ID: 179732  Cd Length: 180  Bit Score: 95.03  E-value: 1.00e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   8 QLYLASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAMAGLACAPTALPVLGADTIVVLGDRVLEK 87
Cdd:PRK04056   1 MIILASSSSTRANLLKEAGIEFEQKSLDFDEESIKKTSPKEFVYLAVKGKLEQFLKKYGNECNLLVADSVVSCGNKILRK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  88 PSDLLDAKDMLEALSGKVHQVMTAVALATPERCDVRLVTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYGIQGIAGKFVSR 167
Cdd:PRK04056  81 AKDKEEAREMLKLQSGNEISVLTCMILKSPEKEWLDLSVTTYRFKKFDEDDLEKYLESGLWQGKAGACMVEGFHKKYIKS 160

                        170
                 ....*....|.
gi 754692813 168 MEGSYSAVVGL 178
Cdd:PRK04056 161 VSGNESTAMGL 171
PRK02478 PRK02478
Maf-like protein; Reviewed
 7-181 2.46e-23

Maf-like protein; Reviewed


Pssm-ID: 167380  Cd Length: 199  Bit Score: 91.72  E-value: 2.46e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   7 PQLYLASGSPRRHELLTQLGYRFEVLRLDVPEQ------REEGEKAQDYVCRLARDKAMAGLACAPTALpVLGADTIVVL 80
Cdd:PRK02478   3 VKLILASKSPFRRALLENAGLEFSAAAADIDERaveaplEESGATPEDVALVLAEAKAIDVSERFPGAL-VIGCDQTMSL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  81 GDRVLEKPSDLLDAKDMLEALSGKVHQVMTAVALATPERCDVRLVTT-NVAFRKLDEAEIEAYWQ-TGEpcdKA----GA 154
Cdd:PRK02478  82 GDEVFHKPKDMEEARRHLQKLSGKTHQLNSAVVLVRDGKVLWRHVSIaHMTMRDLDAGFIGRHLArVGE---KAlssvGA 158

                        170       180
                 ....*....|....*....|....*..
gi 754692813 155 YGIQGIAGKFVSRMEGSYSAVVGLPLL 181
Cdd:PRK02478 159 YQLEGEGIQLFEKIEGDYFTILGLPLL 185
PRK02141 PRK02141
Maf-like protein; Reviewed
 1-181 6.93e-23

Maf-like protein; Reviewed


Pssm-ID: 235009  Cd Length: 207  Bit Score: 90.97  E-value: 6.93e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813   1 MNKNNEPQLYLASGSPRRHELLTQLGYRFEVLRLDVPEQREEGEKAQDYVCRLARDKAM--AGLACAPTALPVLGADTIV 78
Cdd:PRK02141   3 DTVCRPPRLILASSSRYRRELLERLRLPFDVVSPDIDETPLAGETPAATALRLAAAKARavAATIDAPPGALVIGSDQVA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754692813  79 VLGDRVLEKPSDLLDAKDMLEALSGKVHQVMTAVALATPERCDVRL--VTTNVAFRKLDEAEIEAYWQTGEPCDKAGAYG 156
Cdd:PRK02141  83 TFDGLQIGKPGTHERALAQLQAMRGRTVEFHSALCLYDSRTGETQSedVVTRVRFRTLTDAELDAYLRAETPYDVAGSAK 162

                        170       180
                 ....*....|....*....|....*.
gi 754692813 157 IQGIAGKFVSRMEGS-YSAVVGLPLL 181
Cdd:PRK02141 163 SEGLGIALLDAIDSDdPTALVGLPLI 188
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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