|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
7-842 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1609.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 7 EITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVY 86
Cdd:PRK05560 4 RIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAVY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 87 DTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNL 166
Cdd:PRK05560 84 DALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 167 LVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARA 246
Cdd:PRK05560 164 LVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMRAKA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 247 EVEADakTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQL 326
Cdd:PRK05560 244 EIEEI--KGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLYKHTQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 327 QVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEA 406
Cdd:PRK05560 322 QTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPAEA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 407 KAALIARpwdlgnvaamleragddaarpewlepefgvrdgqYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQIA 486
Cdd:PRK05560 402 KEGLMER----------------------------------FGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIA 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 487 ELLHILGSADRLMEVIREELELIRDQFGDARRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKG 566
Cdd:PRK05560 448 DLKDILASPERLLEIIKEELLEIKEKFGDPRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKG 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 567 KSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREYEEGVNV 646
Cdd:PRK05560 528 VSGAKTKEDDFVEHLFVASTHDTLLFFTNRGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYL 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 647 FMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATGVRGIKL 726
Cdd:PRK05560 608 FFATKNGTVKKTSLSEFSNIRSNGIIAINLDEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIKL 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 727 AGEDKVVSLIIPRGEGA-ILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITDAGTLV 805
Cdd:PRK05560 688 REGDEVVSMDVVREDSQeILTVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLI 767
|
810 820 830
....*....|....*....|....*....|....*..
gi 754933817 806 RTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEP 842
Cdd:PRK05560 768 RTRVSEISITGRNTQGVRLIRLDEGDKVVSVARVAEE 804
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-836 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1496.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 1 MSDL--AREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYH 78
Cdd:COG0188 1 MSDPppAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 79 PHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDV 158
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 159 MPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRG 238
Cdd:COG0188 161 LPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 239 KVYIRARAEVEaDAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLN 318
Cdd:COG0188 241 SIRVRAKAEIE-ELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLN 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 319 NLYSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIR 398
Cdd:COG0188 320 QLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIR 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 399 RAPTPAEAKAALIARpwdlgnvaamleragddaarpewlepefgvrdgqYYLTEQQAQAILDLRLQKLTGLEHEKLLDEY 478
Cdd:COG0188 400 ASKDPDEAKEALMER----------------------------------FGLSEIQAEAILDMRLRRLTGLEREKIEDEY 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 479 KELLEQIAELLHILGSADRLMEVIREELELIRDQFGDARRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYE 558
Cdd:COG0188 446 AELLKEIAELEDILASEERLLKIIKEELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYR 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 559 AQRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVR 638
Cdd:COG0188 526 AQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVK 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 639 EYEEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTA 718
Cdd:COG0188 606 EFDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTA 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 719 TGVRGIKLAGEDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMI 798
Cdd:COG0188 686 RGVRGIRLKEGDEVVGMAVVDEEDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLI 765
|
810 820 830
....*....|....*....|....*....|....*...
gi 754933817 799 TDAGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGL 836
Cdd:COG0188 766 TSSGQLIRTPVSDIRVTGRNTQGVRLIRLDEGDKVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
8-841 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1407.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 8 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYD 87
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 88 TIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLL 167
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 168 VNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAE 247
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 248 VEADAKtGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQ 327
Cdd:TIGR01063 241 IEEDSK-GREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQLQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 328 VSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEAK 407
Cdd:TIGR01063 320 VSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 408 AALIARpwdlgnvaamleragddaarpewlepefgvrdgqYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQIAE 487
Cdd:TIGR01063 400 TRLVER----------------------------------FSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIAD 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 488 LLHILGSADRLMEVIREELELIRDQFGDARRTEITAN-SADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKG 566
Cdd:TIGR01063 446 LEDILASEERVLEIIREELEEIKEQFGDPRRTEIVYDeSEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKG 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 567 KSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREYEEGVNV 646
Cdd:TIGR01063 526 VSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYL 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 647 FMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATGVRGIKL 726
Cdd:TIGR01063 606 FFATKNGVVKKTSLTEFSNIRSNGIIAIKLDDGDELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKL 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 727 AGEDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITDAGTLVR 806
Cdd:TIGR01063 686 KNEDFVVSLLVVSEESYLLIVTENGYGKRTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIR 765
|
810 820 830
....*....|....*....|....*....|....*
gi 754933817 807 TRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAE 841
Cdd:TIGR01063 766 TSVQDVSEQGRNTQGVRLIRLDEDDKLVSVSKVAK 800
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
30-507 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 727.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 30 VGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNF 109
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 110 GSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTE 189
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 190 VINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEADAktGRETIIVHEIPYQVN 269
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDE--GRNTIEITELPYQVN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 270 KARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHH-GQPKIMNLK 348
Cdd:cd00187 239 KAKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDPnGRPKKLNLK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 349 DIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAptpAEAKAALIARPWdlgnvaamlerag 428
Cdd:cd00187 319 EILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELE------------- 382
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 754933817 429 ddaarpewlepefgvrdgQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQIAELLHILGSADRLMEVIREELE 507
Cdd:cd00187 383 ------------------KLGFSEIQADAILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELD 443
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
11-499 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 669.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 11 VNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIV 90
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 91 RMAQPFSLRYMLVDGQGNFGSI-DGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVN 169
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 170 GSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINgrrgieeayrtGRGKVYIRARAEVE 249
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 250 adaktGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDES-DKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQV 328
Cdd:smart00434 230 -----DDNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQT 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 329 SFGINMVALH-HGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKAR-DRAHILEALAIALANIDPIIELIRRAPTPA-E 405
Cdd:smart00434 305 TFSINMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDLAkE 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 406 AKAALIARpwdlgnvaamleragddaarpewlepefgvrdgqYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQI 485
Cdd:smart00434 385 AKEKLMER----------------------------------FELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEI 430
|
490
....*....|....
gi 754933817 486 AELLHILGSADRLM 499
Cdd:smart00434 431 EDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
32-507 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 629.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 32 RALPDVRDGLKPVHRRVLYAMNVLGNDwNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGS 111
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFELLNL-DKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 112 -IDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEV 190
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 191 INGCLAYIDDEDISIegLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEAdaktgRETIIVHEIPYQVNK 270
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED-----RKTIVITELPYGVWT 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 271 ARLIEKIAELVKDKRVEGISALRDESDKdGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDI 350
Cdd:pfam00521 233 SDLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 351 ISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEAKAALIARpwdlgnvaamleragdd 430
Cdd:pfam00521 312 LKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE----------------- 374
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754933817 431 aarpewlepefgvrdgqyyLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQIAELLHILGSADRLMEVIREELE 507
Cdd:pfam00521 375 -------------------LSEIQADYLLDMRLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
7-842 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1609.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 7 EITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVY 86
Cdd:PRK05560 4 RIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAVY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 87 DTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNL 166
Cdd:PRK05560 84 DALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 167 LVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARA 246
Cdd:PRK05560 164 LVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMRAKA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 247 EVEADakTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQL 326
Cdd:PRK05560 244 EIEEI--KGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLYKHTQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 327 QVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEA 406
Cdd:PRK05560 322 QTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPAEA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 407 KAALIARpwdlgnvaamleragddaarpewlepefgvrdgqYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQIA 486
Cdd:PRK05560 402 KEGLMER----------------------------------FGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIA 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 487 ELLHILGSADRLMEVIREELELIRDQFGDARRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKG 566
Cdd:PRK05560 448 DLKDILASPERLLEIIKEELLEIKEKFGDPRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKG 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 567 KSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREYEEGVNV 646
Cdd:PRK05560 528 VSGAKTKEDDFVEHLFVASTHDTLLFFTNRGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYL 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 647 FMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATGVRGIKL 726
Cdd:PRK05560 608 FFATKNGTVKKTSLSEFSNIRSNGIIAINLDEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIKL 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 727 AGEDKVVSLIIPRGEGA-ILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITDAGTLV 805
Cdd:PRK05560 688 REGDEVVSMDVVREDSQeILTVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLI 767
|
810 820 830
....*....|....*....|....*....|....*..
gi 754933817 806 RTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEP 842
Cdd:PRK05560 768 RTRVSEISITGRNTQGVRLIRLDEGDKVVSVARVAEE 804
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-836 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1496.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 1 MSDL--AREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYH 78
Cdd:COG0188 1 MSDPppAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 79 PHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDV 158
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 159 MPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRG 238
Cdd:COG0188 161 LPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 239 KVYIRARAEVEaDAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLN 318
Cdd:COG0188 241 SIRVRAKAEIE-ELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLN 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 319 NLYSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIR 398
Cdd:COG0188 320 QLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIR 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 399 RAPTPAEAKAALIARpwdlgnvaamleragddaarpewlepefgvrdgqYYLTEQQAQAILDLRLQKLTGLEHEKLLDEY 478
Cdd:COG0188 400 ASKDPDEAKEALMER----------------------------------FGLSEIQAEAILDMRLRRLTGLEREKIEDEY 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 479 KELLEQIAELLHILGSADRLMEVIREELELIRDQFGDARRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYE 558
Cdd:COG0188 446 AELLKEIAELEDILASEERLLKIIKEELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYR 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 559 AQRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVR 638
Cdd:COG0188 526 AQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVK 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 639 EYEEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTA 718
Cdd:COG0188 606 EFDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTA 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 719 TGVRGIKLAGEDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMI 798
Cdd:COG0188 686 RGVRGIRLKEGDEVVGMAVVDEEDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLI 765
|
810 820 830
....*....|....*....|....*....|....*...
gi 754933817 799 TDAGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGL 836
Cdd:COG0188 766 TSSGQLIRTPVSDIRVTGRNTQGVRLIRLDEGDKVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
8-841 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1407.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 8 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYD 87
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 88 TIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLL 167
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 168 VNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAE 247
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 248 VEADAKtGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQ 327
Cdd:TIGR01063 241 IEEDSK-GREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQLQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 328 VSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEAK 407
Cdd:TIGR01063 320 VSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 408 AALIARpwdlgnvaamleragddaarpewlepefgvrdgqYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQIAE 487
Cdd:TIGR01063 400 TRLVER----------------------------------FSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIAD 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 488 LLHILGSADRLMEVIREELELIRDQFGDARRTEITAN-SADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKG 566
Cdd:TIGR01063 446 LEDILASEERVLEIIREELEEIKEQFGDPRRTEIVYDeSEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKG 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 567 KSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREYEEGVNV 646
Cdd:TIGR01063 526 VSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYL 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 647 FMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATGVRGIKL 726
Cdd:TIGR01063 606 FFATKNGVVKKTSLTEFSNIRSNGIIAIKLDDGDELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKL 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 727 AGEDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITDAGTLVR 806
Cdd:TIGR01063 686 KNEDFVVSLLVVSEESYLLIVTENGYGKRTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIR 765
|
810 820 830
....*....|....*....|....*....|....*
gi 754933817 807 TRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAE 841
Cdd:TIGR01063 766 TSVQDVSEQGRNTQGVRLIRLDEDDKLVSVSKVAK 800
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
1-771 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 863.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 1 MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH 80
Cdd:PRK05561 3 DMSMLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 81 GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP 160
Cdd:PRK05561 83 GDSSIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 161 TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPT-AAIINGRRGIEEAYRTGRGK 239
Cdd:PRK05561 163 ARFPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTgGEIITGRDGIRKAYETGRGS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 240 VYIRARAEVEaDAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDG-MRIVIEVKRDAVG-EVVL 317
Cdd:PRK05561 243 IRVRARWEIE-DLAGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENpVRIVIEPKSNRVDpEALM 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 318 NNLYSQTQLQVSFGINMVALH-HGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIEL 396
Cdd:PRK05561 322 NHLFATTDLESSYRVNMNAIGlDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRI 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 397 IRrapTPAEAKAALIARpwdlgnvaamleragddaarpewlepeFGvrdgqyyLTEQQAQAILDLRLQKLTGLEHEKLLD 476
Cdd:PRK05561 402 IR---ESDEPKANLMAR---------------------------FD-------LSEIQAEAILELRLRRLAKLEEIEIRK 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 477 EYKELLEQIAELLHILGSADRLMEVIREELELIRDQFGDARRTEITANSAD--INIEDLINQEDVVVTLSHQGYVKyqpl 554
Cdd:PRK05561 445 EQDELRKEIAELEAILASERKLRKLIKKELKADAKKFGDPRRTPIEEAEEAiaIDEEALIPDEPVTVVLSKKGWVR---- 520
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 555 tdyeaqRRGGKGKSAA--RIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEAsRGArGRPIVNLLPLEADERIT 632
Cdd:PRK05561 521 ------RAKGHSIDASglSFKEGDSLLFAFEARTTDKLLLFTSTGRVYSLPVHELPSA-RGD-GEPLTGLVDLAPGEEIV 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 633 AILPvreYEEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVR 712
Cdd:PRK05561 593 HVLA---FDPDQKLLLASSAGYGFVVTLEDLVARTRAGKAVINLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSELP 669
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754933817 713 AMGRtATGVRGIKL-AGEDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPT--KSRATQGV 771
Cdd:PRK05561 670 ELGK-GKGVKLINLpKDDDGLVDLRVLNPEDGLVLLTAGKRKLKLKPSELEKyrGKRARRGR 730
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
30-507 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 727.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 30 VGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNF 109
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 110 GSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTE 189
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 190 VINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEADAktGRETIIVHEIPYQVN 269
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDE--GRNTIEITELPYQVN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 270 KARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHH-GQPKIMNLK 348
Cdd:cd00187 239 KAKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDPnGRPKKLNLK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 349 DIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAptpAEAKAALIARPWdlgnvaamlerag 428
Cdd:cd00187 319 EILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELE------------- 382
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 754933817 429 ddaarpewlepefgvrdgQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQIAELLHILGSADRLMEVIREELE 507
Cdd:cd00187 383 ------------------KLGFSEIQADAILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELD 443
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
11-499 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 669.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 11 VNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIV 90
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 91 RMAQPFSLRYMLVDGQGNFGSI-DGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVN 169
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 170 GSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINgrrgieeayrtGRGKVYIRARAEVE 249
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 250 adaktGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDES-DKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQV 328
Cdd:smart00434 230 -----DDNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQT 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 329 SFGINMVALH-HGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKAR-DRAHILEALAIALANIDPIIELIRRAPTPA-E 405
Cdd:smart00434 305 TFSINMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDLAkE 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 406 AKAALIARpwdlgnvaamleragddaarpewlepefgvrdgqYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQI 485
Cdd:smart00434 385 AKEKLMER----------------------------------FELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEI 430
|
490
....*....|....
gi 754933817 486 AELLHILGSADRLM 499
Cdd:smart00434 431 EDLEKILASEEWLN 444
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
8-802 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 646.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 8 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYD 87
Cdd:PRK13979 13 IIKIPLEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSVYD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 88 TIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLL 167
Cdd:PRK13979 93 AMVILAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 168 VNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAE 247
Cdd:PRK13979 173 VNGAFGIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTKELMNYIKGPDLPTGGILIGKKSLLSAYETGEGKVTLRAKTK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 248 VEaDAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKR----VEGISALRDESDKDGMRIVIEVKRDA---VGEVVLNNL 320
Cdd:PRK13979 253 IE-KLENGRLGIVITEFPYRRNKAKLLQTISEMTADKKhskaLENISDIRDESDRNGIRAVIEFKKSAdedVAEKVLKYL 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 321 YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA 400
Cdd:PRK13979 332 YKKTDLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIKTIRSS 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 401 PTPAEAKAALIARpwdlgnvaamleragddaarpewlepeFGvrdgqyyLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE 480
Cdd:PRK13979 412 KSKKDASENLIEK---------------------------FG-------FTDEQAEAILELMLYRLTGLEIVAFEKEYKE 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 481 LLEQIAELLHILGSADRLMEVIREELELIRDQFGDARRTEITA--NSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYe 558
Cdd:PRK13979 458 LEKLIKKLTKILSSEKELLKVIKKELKEVKEKYGDERRTSIIEddEKAKIDVEELIVVEDVVITLSNEGFIKRIPLKSY- 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 559 aqRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPE---ASRGARGRPIVNLLPLEaDERITAIL 635
Cdd:PRK13979 537 --NRSNSNVEDIEYREGDFNKFLIQSNTKDTLLIFTDKGNMYQIKGINIPEfkwKEKGERLDEIIKGIDLE-SEKIIEAY 613
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 636 PVREYEEGVNVFMATASGTVKKTALTEFSRPRSAgIIAVNLNEGDELIGVDLTSGSDEVMLFSAAGKV-VRF--KEDAVR 712
Cdd:PRK13979 614 SIEDFTPQKDFIFITDSGGIKKTSLDKFVTNYTK-LMALKLKKGEKLIKVKLVDRTREEKFIKIKTKKgLSFtvEEPELE 692
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 713 AMGRTATGVRGIKLAGEDKVVSL-IIPRGEGAILTVTQNGYGKrtaadeyptksratqgvisIKVTERNGSVVGAVQVDD 791
Cdd:PRK13979 693 PVDRNIIGYQLFDLLPNDSIKKVdFCDNYEYKEFYVNINKKGI-------------------IKISDKDNKSSISVFTNS 753
|
810
....*....|.
gi 754933817 792 CDQIMMITDAG 802
Cdd:PRK13979 754 SKNLLIFSDEG 764
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
13-779 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 631.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 13 IEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRM 92
Cdd:TIGR01061 6 LEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYDAMVRM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 93 AQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSS 172
Cdd:TIGR01061 86 SQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLLINGAT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 173 GIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEADa 252
Cdd:TIGR01061 166 GIAAGYATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIRAKIEIEVN- 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 253 KTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGI 332
Cdd:TIGR01061 245 KNGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESDRNGIRIIIELKKDANAEKILNFLFKHTDLQINYNF 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 333 NMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEAKAALIA 412
Cdd:TIGR01061 325 NMVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKENLID 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 413 RpwdlgnvaamleragddaarpewlepefgvrdgqYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQIAELLHIL 492
Cdd:TIGR01061 405 N----------------------------------FKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQII 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 493 GSADRLMEVIREELELIRDQFGDARRTEI--TANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKGKsaa 570
Cdd:TIGR01061 451 ASEKARNKLLKKQLEEYKKQFAQQRRSQIedFINQIKINESELIENEDYYVLITKAGYIKRTSNRSFASSKYTDFGS--- 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 571 riKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREYE-EGVNVFMA 649
Cdd:TIGR01061 528 --KDDDILFAQTIANTTDQILIFTSLGNIINIPVHKLADIRWKDLGEHLSNKITFDENETIVFVGTMNEFDvDQPILVLA 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 650 TASGTVKKTALTEFS-RPRSAGIIAVNLNEGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATGVRGIKLAG 728
Cdd:TIGR01061 606 SKLGMVKRIELTELNiKRNSKATLCIKLKDKDHLISAFLQQKDKLICLVSDLGYALVFHTNEIPVVGAKAAGVKGMKLKE 685
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|.
gi 754933817 729 EDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTER 779
Cdd:TIGR01061 686 DDQVKSGVIFEANESLVLLTQRGSVKRLSISELVVTSRAATGKKLLPLKKK 736
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
32-507 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 629.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 32 RALPDVRDGLKPVHRRVLYAMNVLGNDwNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGS 111
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFELLNL-DKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 112 -IDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEV 190
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 191 INGCLAYIDDEDISIegLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEAdaktgRETIIVHEIPYQVNK 270
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED-----RKTIVITELPYGVWT 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 271 ARLIEKIAELVKDKRVEGISALRDESDKdGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDI 350
Cdd:pfam00521 233 SDLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 351 ISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEAKAALIARpwdlgnvaamleragdd 430
Cdd:pfam00521 312 LKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE----------------- 374
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754933817 431 aarpewlepefgvrdgqyyLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQIAELLHILGSADRLMEVIREELE 507
Cdd:pfam00521 375 -------------------LSEIQADYLLDMRLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
8-716 |
3.31e-170 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 511.76 E-value: 3.31e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 8 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYD 87
Cdd:TIGR01062 1 IENIDLGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 88 TIVRMAQPFSLRYMLVDGQGNFGSIDG-DSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNL 166
Cdd:TIGR01062 81 AMVLMAQPFSYRYPLVDGQGNWGAPDDpKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 167 LVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAA-IINGRRGIEEAYRTGRGKVYIRAR 245
Cdd:TIGR01062 161 LLNGTTGIAVGMATDIPPHNLHELADAALYLIDNPKAGLDDILNIVQGPDFPTEAeIIDKAEEIRKIYETGRGSFRMRAR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 246 AEVEADAktgretIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESD-KDGMRIVIEVKRDAVG-EVVLNNLYSQ 323
Cdd:TIGR01062 241 WKKEDGQ------IVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDhENPIRVVIVPRSNRVDpDIVMEHLFAT 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 324 TQLQVSFGINM--VALHHgQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAP 401
Cdd:TIGR01062 315 TDLEKSYRLNMnmIGLDN-VPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIREED 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 402 TPaeaKAALIARpwdlgnvaamleragddaarpewlepefgvrdgqYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKEL 481
Cdd:TIGR01062 394 EP---KTILMER----------------------------------FKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSEL 436
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 482 LEQIAELLHILGSADRLMEVIREELELIRDQFGDARRT-----EITANSADInieDLINQEDVVVTLSHQGYVKYQPLTD 556
Cdd:TIGR01062 437 EKERAILEKILKSERELNQLVKKEIQADATKYGLARRSsleerEEAKQVSEI---DMIPKEPVTIILSKMGWVRSAKGHD 513
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 557 YEAqrrggkgkSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEAsRGaRGRPIVNLLPLEADERITAILP 636
Cdd:TIGR01062 514 IDL--------STLKYKAGDSEKAIIEGKSNQKVVFIDSTGRSYALDPDNLPSA-RG-QGEPLTGKLLLPIGATITNILM 583
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 637 VREYEEgvnVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIG-VDLTSGSDEVMLFSAAGKVVRFKEDAVRAMG 715
Cdd:TIGR01062 584 YSPNQL---LLMASDAGYGFLCNFNDLIARNKAGKALINLPENASVIApLPVNGDSDMIAAITEAGRMLVFPIDDLPELS 660
|
.
gi 754933817 716 R 716
Cdd:TIGR01062 661 K 661
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
10-383 |
1.79e-68 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 239.61 E-value: 1.79e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 10 PVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLgNDWNkaYKKSARVVGDVIgKYHPHGDSAVYDTI 89
Cdd:PRK09631 1 MMDIKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSLFEM-HDGK--FHKVANVVGNTM-KYHPHGDASIYEAL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 90 VRMAQpfslRYMLVDGQGNFGSI-DGDSAAAMRYTEIRLAKIAHELMadLEKETVDFVDNYDGTEKIPDVMPTKIPNLLV 168
Cdd:PRK09631 77 VNLAN----KDLFIDKQGNFGNLfTGDPASAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPVILI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 169 NGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEglmehipgPDFPTAAIINgrrgiEEAYRTGRGKVYIRARAEv 248
Cdd:PRK09631 151 QGAEGIAVGMATKILPHNFNEILQAVKSELLGESFALY--------PDFPTGGIVD-----VSEYADGNGKVLVRAKIE- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 249 EADAKtgreTIIVHEIPYQVNKARLIEKIAELVKDKRVEgISALRDESdKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQV 328
Cdd:PRK09631 217 TKDEK----TIVIREIPFGTTTESLIASIEKAARKGKIK-ISSINDYT-AENVEIEIKLPRGVYASEVIEALYAYTDCEV 290
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 754933817 329 SFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRtiFELrkarDRAHILEAL 383
Cdd:PRK09631 291 SISVNLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKME--LEL----ERAKLLEKI 339
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
18-521 |
1.02e-52 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 198.30 E-value: 1.02e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 18 KSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDwnkAYKKSARVVGDVIgKYHPHGDSAVYDTIVRMAQpfs 97
Cdd:PRK12758 28 KNWFLDYASYVILERAVPHIEDGLKPVQRRILHSMKEMDDG---RYNKVANVVGHTM-QYHPHGDASIGDALVQLGQ--- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 98 lRYMLVDGQGNFGSI-DGDSAAAMRYTEIRLAKIAHELMadLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAV 176
Cdd:PRK12758 101 -KDLLIDTQGNWGNIlTGDGAAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIAV 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 177 GMATNIPPHNLTEVINGCLAYIDDEDISIEglmehipgPDFPTAAIIN------GRRGieeayrtgrGKVYIRARAEvEA 250
Cdd:PRK12758 178 GLSTKILPHNFNELIDASIAYLKGKEFKLY--------PDFPTGGIIDvsnyndGERG---------GRVRVRAKIE-KL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 251 DAKtgreTIIVHEIPYQVNKARLIEKIAEL-----VKDKRVEGISAlrdesdkDGMRIVIEVKRDAVGEVVLNNLYSQTQ 325
Cdd:PRK12758 240 DKK----TLVITEIPYGTTTSSLIDSILKAndkgkIKIKKVEDNTA-------ADVEILVHLAPGVSPDKTIDALYAFTD 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 326 LQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHI--LEALAIAlaniDPIIELIRRAPTP 403
Cdd:PRK12758 309 CEVSISPNACVIIDNKPHFLGVSDILRRSTDHTVSLLKQELEIRLSELEEQWHFasLEKIFIE----ERIYKEIEEAETW 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 404 AEAKAALIARpwdlgnvaamleragddaarpewLEPEFgvrdGQYY--LTEQQAQAILDLRLQKLTGLEHEKLLDEYKEL 481
Cdd:PRK12758 385 EAVIEAIDKG-----------------------LEPFK----KQFIreVTEDDIVRLTEIKIKRISKFDSDKADELIARL 437
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 754933817 482 LEQIAELLHILgsaDRLMEVIREELELIRDQFGDA--RRTEI 521
Cdd:PRK12758 438 EAEIAEVKHHL---AHLTDYAIAYFTNLKKKYGKGreRKTEI 476
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
12-351 |
1.96e-46 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 173.54 E-value: 1.96e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 12 NIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLgnDWNKAYKksarvVGDVIGK---YHPHGDSAVYDT 88
Cdd:PRK09630 3 DVSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTLFRM--DDGKMHK-----VANIAGRtmaLHPHGDAPIVEA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 89 IVRMAQpfslRYMLVDGQGNFGS-IDGDSAAAMRYTEIRLAKIAHELMadLEKETVDFVDNYDGTEKIPDVMPTKIPNLL 167
Cdd:PRK09630 76 LVVLAN----KGYLIDTQGNFGNpLTGDPHAAARYIEARLSPLAKEVL--FNTDLMTFHDSYDGREKEPDILPAKLPLLL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 168 VNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEglmehipgPDFPTAAIINGrrgieEAYRTGRGKVYIRARAE 247
Cdd:PRK09630 150 LHGVDGIAVGMTTKIFPHNFCELLEAQIAILNDQPFTLL--------PDFPSGGTMDA-----SEYQDGLGSITLRASID 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 248 VEADaktgrETIIVHEIPYQVNKARLIEKIAELVKdKRVEGISALRDESdKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQ 327
Cdd:PRK09630 217 IIND-----KTLLIKEICPSTTTETLIRSIENAAK-RGIIKIDSIQDFS-TDLPHIEIKLPKGIYAKDLLRPLFTHTECQ 289
|
330 340
....*....|....*....|....
gi 754933817 328 VSFGINMVALHHGQPKIMNLKDII 351
Cdd:PRK09630 290 VILTSRPTAIYQNKPVETSISEIL 313
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
22-397 |
2.82e-42 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 160.22 E-value: 2.82e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 22 LDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDV--IGkYHpHGDSAVYDTIVRMAQPFSLR 99
Cdd:PHA02592 17 LEYAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGVadLG-YH-HGETSAQDAGALMANTWNNN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 100 YMLVDGQGNFGSIDGDSAAAMRYTEIRLakiaHELMADLEKETvDFVDNYDGTEKIPDV--MPTkIPNLLVNGSSGIAVG 177
Cdd:PHA02592 95 IPLLDGQGNFGSRLVQKAAAARYIFARV----HDNFRKIYKDE-DLAPVHEDPEHIPPAfyLPI-IPMVLLNGVSGIATG 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 178 MATNIPPHNLTEVINGCLAYIDDEDISieglmehIPGPDFPtaaiinGRRGieEAYRTGRGKVYIRARAEVeadakTGRE 257
Cdd:PHA02592 169 YATNILPHSPKSVIKAVLAALNGKDIT-------EPKVQFP------EFKG--EVVEIEPGSYEIRGTYEL-----NGKT 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 258 TIIVHEIPYQVNKARLIEKIAELVKDKRVEGIsalrDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVAL 337
Cdd:PHA02592 229 KLHITEIPVKYDRETYVAVLDPLEEKGKIVSY----DDCTEDGFRFKVTLKREENEEATHEKIMKDFGLIERVSQNITVI 304
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754933817 338 H-HGQPKIM-NLKDIISAFVRHRREVVTRRTIFELRKARdrahilEALAIALANIDPIIELI 397
Cdd:PHA02592 305 NeNGKLKVYeNAEDLIRDFVEIRKTYVQKRIQYEIKETE------EAFDLALAKAEFIKRVI 360
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
32-483 |
2.35e-25 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 113.26 E-value: 2.35e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 32 RALPDVRDGLKPVHRRVLYAmnVLGNDWnKAYKKSARVVGDVI--GKYHpHGDSAVYDTIVRMAQPF--SLRYMLVDGQG 107
Cdd:PLN03128 673 RSIPSMVDGLKPSQRKVLFA--CFKRNL-KSEIKVAQLSGYVAehSAYH-HGEASLASTIIGMAQDFvgSNNINLLTPSG 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 108 NFGS--IDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNyDGTEKIPD-VMPTkIPNLLVNGSSGIAVGMATNIPP 184
Cdd:PLN03128 749 QFGTrlQGGKDAASARYIFTRLSPITRALFPKDDDVLLNYLNE-DGQSIEPEwYCPI-IPMVLVNGSEGIGTGWSTFIPN 826
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 185 HNLTEVINGCLAYIDDEDisieglmehiPGPDFPTAAIINGRrgIEEAYRTGRGKVYIRARAEveadaKTGRETIIVHEI 264
Cdd:PLN03128 827 YNPRDIIANIRRLLRGEE----------LEPMHPWYRGFKGT--ITEVSTSRSGSYTVTGIIE-----QIGDTTIRITEL 889
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 265 PYQV---NKARLIEKIAELVKDKRVEgISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGI-NMVALHH- 339
Cdd:PLN03128 890 PVRKwtqDYKEFLEALLTGTKKKEPE-IKDFKENHTDTTVHFTVTLSEEKMARALAEGLEKKFKLSTTISTsNMHLFDKd 968
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 340 GQPKIMNL-KDIISAFVRHR-------REVVTRRTIFELRKARDRAHILEALA---IALAN---IDPIIELIRR--APTP 403
Cdd:PLN03128 969 GKIKKYDSpEDILEEFFHLRldlyvkrKEVLLENLEYELKKLDNKARFILAVVkgeIVVNNrkrAELLAELEEKgfDKFP 1048
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 404 AEAKAALIARPWDLGNVAAMLERAGDDAARPEWlepEFGVRDGQYYLTEQQAQAILDLR---------LQKLTGLEH-EK 473
Cdd:PLN03128 1049 KTAKISETNVVGDRDGEASEEEEASDNELAKSY---DYLLGMPISSLTLEKVDELRAERakketeveeLKKTTPEDLwRK 1125
|
490
....*....|
gi 754933817 474 LLDEYKELLE 483
Cdd:PLN03128 1126 DLDAFEEALD 1135
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
32-523 |
3.95e-25 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 112.83 E-value: 3.95e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 32 RALPDVRDGLKPVHRRVLYAMnvlgndWNKAYKKSARVVgDVIG------KYHpHGDSAVYDTIVRMAQPF----SLRYM 101
Cdd:PTZ00108 680 RSIPSLVDGLKPGQRKILFAC------FKRNLKNEIKVA-QLSGyvsehsAYH-HGEQSLQQTIVGMAQNFvgsnNINLL 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 102 LVDGQgnFGS--IDGDSAAAMRYTEIRLAKIA----HElmADleketvDFVDNY---DGTEKIPD-VMPTkIPNLLVNGS 171
Cdd:PTZ00108 752 YPCGQ--FGSrlQGGKDHAAARYIFTKLSKITryifPE--ED------DPILDYledDGQSVEPFyYVPI-IPMVLVNGA 820
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 172 SGIAVGMATNIPPHNLTEVINGCLAYIDDEDisiegLMEHIPgpdfptaaiingrrgieeAYRTGRGKvyIRARAEVEAD 251
Cdd:PTZ00108 821 EGIGTGFSTSIPNYNPLDIIDNLRRRLNGEE-----VRPLVP------------------WYRGFKGT--IERNPKGKFI 875
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 252 AK-----TGRETIIVHEIPYQV---------NKARLIEKiaELVKDkrvegisaLRDESDKDGMRIVIEVKRDAVGEVVL 317
Cdd:PTZ00108 876 SKgiyekVPDGTVEITELPIGKwtedykeflESETLKEK--DVIVD--------YRDYSTANTVHFTVKLNDGVLEQWEE 945
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 318 NNLYSQTQLQVSFGI-NMVALHHGQ--PKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALA---------- 384
Cdd:PTZ00108 946 EGIEKVFKLKSTISTtNMVLFDENGkiKKYSDALDILKEFYLVRLDLYKKRKEYLLGKLERELARLSNKVrfikhvinge 1025
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 385 IALAN---IDPIIELIRRAPTP----AEAKAALIARPWDLGNvaamlerAGDDAARPEWLEPEFGVRDGQYYLteqqaqa 457
Cdd:PTZ00108 1026 LVITNakkKDLVKELKKLGYVRfkdiIKKKSEKITAEEEEGA-------EEDDEADDEDDEEELGAAVSYDYL------- 1091
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 458 iLDLRLQKLTgLEH-EKLLDEYKELLEQIAELLHIlgsadrlmEVI---REELELIRDQFGDARRTEITA 523
Cdd:PTZ00108 1092 -LSMPIWSLT-KEKvEKLNAELEKKEKELEKLKNT--------TPKdmwLEDLDKFEEALEEQEEVEEKE 1151
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
32-201 |
2.91e-14 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 77.60 E-value: 2.91e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 32 RALPDVRDGLKPVHRRVLYAmnvlgnDWNKAYKKSARV---VGDV--IGKYHpHGDSAVYDTIVRMAQPF----SLRYML 102
Cdd:PLN03237 698 RSIPSMVDGLKPGQRKILFC------SFKRNFVKEAKVaqlSGYVseHSAYH-HGEQSLASTIIGMAQDFvgsnNINLLL 770
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933817 103 VDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNyDGTEKIPD-VMPTkIPNLLVNGSSGIAVGMATN 181
Cdd:PLN03237 771 PNGQFGTRLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDYLNE-DGQSIEPTwYMPI-IPTVLVNGAEGIGTGWSTF 848
|
170 180
....*....|....*....|
gi 754933817 182 IPPHNLTEVINGCLAYIDDE 201
Cdd:PLN03237 849 IPNYNPRDIVANIRRLLNGE 868
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
692-737 |
1.40e-12 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 62.89 E-value: 1.40e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 754933817 692 DEVMLFSAAGKVVRFKEDAVRAMGRTATGVRGIKLAGEDKVVSLII 737
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLV 46
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
793-839 |
6.16e-11 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 58.27 E-value: 6.16e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 754933817 793 DQIMMITDAGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRV 839
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
744-790 |
1.70e-09 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 54.03 E-value: 1.70e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 754933817 744 ILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTErNGSVVGAVQVD 790
Cdd:pfam03989 3 LLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKE-GDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
588-638 |
7.15e-09 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 52.10 E-value: 7.15e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 754933817 588 DTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNllpLEADERITAILPVR 638
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGIN---LKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
538-585 |
1.04e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 51.72 E-value: 1.04e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 754933817 538 DVVVTLSHQGYVKYQPLTDYEAQRRGGKGKSAARIKEEDFIDRLLVAN 585
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
645-689 |
4.66e-06 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 44.40 E-value: 4.66e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 754933817 645 NVFMATASGTVKKTALTEFSRPR--SAGIIAVNLNEGDELIGVDLTS 689
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGrgAKGVKGINLKEGDKVVSVLVVN 48
|
|
| |
