NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|754933827|ref|WP_042290605|]
View 

MULTISPECIES: class I ribonucleotide reductase maintenance protein YfaE [Citrobacter]

Protein Classification

ferredoxin-like diferric-tyrosyl radical cofactor maintenance protein YfaE( domain architecture ID 10793447)

ferredoxin-like diferric-tyrosyl radical cofactor maintenance protein YfaE is a 2Fe-2S ferredoxin involved in cofactor maintenance and assembly

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK10713 PRK10713
2Fe-2S ferredoxin-like protein;
1-84 1.89e-57

2Fe-2S ferredoxin-like protein;


:

Pssm-ID: 182668 [Multi-domain]  Cd Length: 84  Bit Score: 170.68  E-value: 1.89e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933827  1 MGRVTLRITGTQLLCQDEHPSLLAALESHNVEVEYQCREGYCGSCRIRLVAGQVDWLTEPLAFVQPDEILPCCCRAKGDI 80
Cdd:PRK10713  1 MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDI 80


                ....
gi 754933827 81 EIEM 84
Cdd:PRK10713 81 EIEM 84
 
Name Accession Description Interval E-value
PRK10713 PRK10713
2Fe-2S ferredoxin-like protein;
1-84 1.89e-57

2Fe-2S ferredoxin-like protein;


Pssm-ID: 182668 [Multi-domain]  Cd Length: 84  Bit Score: 170.68  E-value: 1.89e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933827  1 MGRVTLRITGTQLLCQDEHPSLLAALESHNVEVEYQCREGYCGSCRIRLVAGQVDWLTEPLAFVQPDEILPCCCRAKGDI 80
Cdd:PRK10713  1 MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDI 80


                ....
gi 754933827 81 EIEM 84
Cdd:PRK10713 81 EIEM 84
Fdx COG0633
Ferredoxin [Energy production and conversion];
1-84 6.85e-16

Ferredoxin [Energy production and conversion];


Pssm-ID: 440398 [Multi-domain]  Cd Length: 87  Bit Score: 65.64  E-value: 6.85e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933827  1 MGRVTLRITGTQLLCqDEHPSLLAALESHNVEVEYQCREGYCGSCRIRLVAGQVD-----WLTEPLafVQPDEILPCCCR 75
Cdd:COG0633   1 MPKVTFIPEGHTVEV-PAGESLLEAALRAGIDLPYSCRSGACGTCHVRVLEGEVDhreedALSDEE--RAAGSRLACQAR 77


                ....*....
gi 754933827 76 AKGDIEIEM 84
Cdd:COG0633  78 PTSDLVVEL 86
fer2 cd00207
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in ...
 17-83 5.24e-13

2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis and ferredoxins, which participate in redox chains (from bacteria to mammals). Fold is ismilar to thioredoxin.


Pssm-ID: 238126 [Multi-domain]  Cd Length: 84  Bit Score: 58.18  E-value: 5.24e-13
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933827 17 DEHPSLLAALESHNVEVEYQCREGYCGSCRIRLVAGQVDWLTEPLAF---VQPDEILPCCCRAKGDIEIE 83
Cdd:cd00207  15 PEGETLLDAAREAGIDIPYSCRAGACGTCKVEVVEGEVDQSDPSLLDeeeAEGGYVLACQTRVTDGLVIE 84
Fer2 pfam00111
2Fe-2S iron-sulfur cluster binding domain;
4-77 3.11e-09

2Fe-2S iron-sulfur cluster binding domain;


Pssm-ID: 395061 [Multi-domain]  Cd Length: 77  Bit Score: 48.67  E-value: 3.11e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754933827   4 VTLRITGTQLLCQDEHPSLLAALESHNVEVEYQCREGYCGSCRIRLVAGQVD---WLTEPLAFVQPDEILPCCCRAK 77
Cdd:pfam00111  1 VTINGKGVTIEVPDGETTLLDAAEEAGIDIPYSCRGGGCGTCAVKVLEGEDQsdqSFLEDDELAAGYVVLACQTYPK 77
 
Name Accession Description Interval E-value
PRK10713 PRK10713
2Fe-2S ferredoxin-like protein;
1-84 1.89e-57

2Fe-2S ferredoxin-like protein;


Pssm-ID: 182668 [Multi-domain]  Cd Length: 84  Bit Score: 170.68  E-value: 1.89e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933827  1 MGRVTLRITGTQLLCQDEHPSLLAALESHNVEVEYQCREGYCGSCRIRLVAGQVDWLTEPLAFVQPDEILPCCCRAKGDI 80
Cdd:PRK10713  1 MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDI 80


                ....
gi 754933827 81 EIEM 84
Cdd:PRK10713 81 EIEM 84
Fdx COG0633
Ferredoxin [Energy production and conversion];
1-84 6.85e-16

Ferredoxin [Energy production and conversion];


Pssm-ID: 440398 [Multi-domain]  Cd Length: 87  Bit Score: 65.64  E-value: 6.85e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933827  1 MGRVTLRITGTQLLCqDEHPSLLAALESHNVEVEYQCREGYCGSCRIRLVAGQVD-----WLTEPLafVQPDEILPCCCR 75
Cdd:COG0633   1 MPKVTFIPEGHTVEV-PAGESLLEAALRAGIDLPYSCRSGACGTCHVRVLEGEVDhreedALSDEE--RAAGSRLACQAR 77


                ....*....
gi 754933827 76 AKGDIEIEM 84
Cdd:COG0633  78 PTSDLVVEL 86
fer2 cd00207
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in ...
 17-83 5.24e-13

2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis and ferredoxins, which participate in redox chains (from bacteria to mammals). Fold is ismilar to thioredoxin.


Pssm-ID: 238126 [Multi-domain]  Cd Length: 84  Bit Score: 58.18  E-value: 5.24e-13
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933827 17 DEHPSLLAALESHNVEVEYQCREGYCGSCRIRLVAGQVDWLTEPLAF---VQPDEILPCCCRAKGDIEIE 83
Cdd:cd00207  15 PEGETLLDAAREAGIDIPYSCRAGACGTCKVEVVEGEVDQSDPSLLDeeeAEGGYVLACQTRVTDGLVIE 84
PRK07609 PRK07609
CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated
 3-83 1.27e-12

CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated


Pssm-ID: 181058 [Multi-domain]  Cd Length: 339  Bit Score: 61.04  E-value: 1.27e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933827   3 RVTLRITGTQLLCQDEHPSLLAALeSHNVEVEYQCREGYCGSCRIRLVAGQVDWLTEPLAFVQPDE-----ILPCCCRAK 77
Cdd:PRK07609   4 QVTLQPSGRQFTAEPDETILDAAL-RQGIHLPYGCKNGACGSCKGRLLEGEVEQGPHQASALSGEEraageALTCCAKPL 82


                 ....*.
gi 754933827  78 GDIEIE 83
Cdd:PRK07609  83 SDLVLE 88
PRK10684 PRK10684
HCP oxidoreductase, NADH-dependent; Provisional
 21-83 2.34e-11

HCP oxidoreductase, NADH-dependent; Provisional


Pssm-ID: 236735 [Multi-domain]  Cd Length: 332  Bit Score: 57.41  E-value: 2.34e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754933827  21 SLLAALESHNVEVEYQCREGYCGSCRIRLVAGqvDWLTEPLAFVQPDEI-----LPCCCRAKGDIEIE 83
Cdd:PRK10684 267 TLLEALESNKVPVVAACRAGVCGCCKTKVVSG--EYTVSSTMTLTPAEIaqgyvLACSCHPQGDLVLA 332
Fer2 pfam00111
2Fe-2S iron-sulfur cluster binding domain;
4-77 3.11e-09

2Fe-2S iron-sulfur cluster binding domain;


Pssm-ID: 395061 [Multi-domain]  Cd Length: 77  Bit Score: 48.67  E-value: 3.11e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754933827   4 VTLRITGTQLLCQDEHPSLLAALESHNVEVEYQCREGYCGSCRIRLVAGQVD---WLTEPLAFVQPDEILPCCCRAK 77
Cdd:pfam00111  1 VTINGKGVTIEVPDGETTLLDAAEEAGIDIPYSCRGGGCGTCAVKVLEGEDQsdqSFLEDDELAAGYVVLACQTYPK 77
PTZ00038 PTZ00038
ferredoxin; Provisional
 3-83 1.33e-08

ferredoxin; Provisional


Pssm-ID: 240237 [Multi-domain]  Cd Length: 191  Bit Score: 49.06  E-value: 1.33e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933827   3 RVTLRIT-GTQLLCQDEHPSLLAALESHNVEVEYQCREGYCGSCRIRLVAGQVDwlTEPLAFVQPDE-----ILPCCCRA 76
Cdd:PTZ00038  97 NITLQTPdGEKVIECDEDEYILDAAERQGVELPYSCRGGSCSTCAAKLLEGEVD--NEDQSYLDDEQlkkgyCLLCTCYP 174


                 ....*..
gi 754933827  77 KGDIEIE 83
Cdd:PTZ00038 175 KSDCTIE 181
COG3894 COG3894
Uncharacterized 2Fe-2S and 4Fe-4S clusters-containing protein, contains DUF4445 domain ...
 1-83 3.32e-08

Uncharacterized 2Fe-2S and 4Fe-4S clusters-containing protein, contains DUF4445 domain [Function unknown];


Pssm-ID: 443101 [Multi-domain]  Cd Length: 621  Bit Score: 48.65  E-value: 3.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933827   1 MGRVTLRITGTQLLCQ-DEHPSLLAALESHNVEVEYQCR-EGYCGSCRIRLVAGQVDWLTE-PLAFVQPDEI-----LPC 72
Cdd:COG3894    1 MPKVKVTFLPSGKRVEvEAGTTLLDAAREAGVDIDAPCGgRGTCGKCKVKVEEGEFSPVTEeERRLLSPEELaegyrLAC 80

                         90
                 ....*....|.
gi 754933827  73 CCRAKGDIEIE 83
Cdd:COG3894   81 QARVLGDLVVE 91
PRK05713 PRK05713
iron-sulfur-binding ferredoxin reductase;
22-83 1.58e-06

iron-sulfur-binding ferredoxin reductase;


Pssm-ID: 235575 [Multi-domain]  Cd Length: 312  Bit Score: 43.95  E-value: 1.58e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754933827  22 LLAALESHNVEVEYQCREGYCGSCRIRLVAGQV-DWLTEPLAFVQPDE--ILPCCCRAKGDIEIE 83
Cdd:PRK05713  19 LLDALNAAGVAVPYSCRAGSCHACLVRCLQGEPeDALPEALAAEKREQgwRLACQCRVVGDLRVE 83
PLN03136 PLN03136
Ferredoxin; Provisional
 2-83 1.43e-04

Ferredoxin; Provisional


Pssm-ID: 178681 [Multi-domain]  Cd Length: 148  Bit Score: 37.81  E-value: 1.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754933827   2 GRVTLRIT---------GTQLLCQDEHPSLLAALESHNVEVEYQCREGYCGSCRIRLVAGQVDWLTEplAFVQPDEI--- 69
Cdd:PLN03136  47 GRVTAMATykvkfitpeGEQEVECEEDVYVLDAAEEAGIDLPYSCRAGSCSSCAGKVVSGSIDQSDQ--SFLDDEQIseg 124

                         90
                 ....*....|....*.
gi 754933827  70 --LPCCCRAKGDIEIE 83
Cdd:PLN03136 125 yvLTCVAYPTSDVVIE 140
petF CHL00134
ferredoxin; Validated
 22-82 5.36e-04

ferredoxin; Validated


Pssm-ID: 177056 [Multi-domain]  Cd Length: 99  Bit Score: 35.47  E-value: 5.36e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 754933827 22 LLAALESHNVEVEYQCREGYCGSCRIRLVAGQVDwlTEPLAFVQPDEI-----LPCCCRAKGDIEI 82
Cdd:CHL00134 27 ILDAAEEQGIDLPYSCRAGACSTCAGKVTEGTVD--QSDQSFLDDDQLeagfvLTCVAYPTSDCTI 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH