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Conserved domains on  [gi|757596975|ref|WP_042844680|]
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MULTISPECIES: ferric ABC transporter ATP-binding protein [Providencia]

Protein Classification

ferric ABC transporter ATP-binding protein( domain architecture ID 11485344)

ferric ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex FbpABC and is responsible for coupling the energy of ATP hydrolysis to the import of Fe(3+) ions

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
1-346 0e+00

ferric ABC transporter ATP-binding protein;


:

Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 754.63  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHNFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDI 80
Cdd:PRK11432   1 MTQKNFVVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQRDI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 CMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:PRK11432  81 CMVFQSYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDA 240
Cdd:PRK11432 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRFMASFMGDA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 241 NIFPATLTHDSVNIFNYHLPRPAQLATD--NTEITVGVRPEAITLSLQGDDSQRCTVTHVAYMGPQYEVTVDWHGQSMLL 318
Cdd:PRK11432 241 NIFPATLSGDYVDIYGYRLPRPAAFAFNlpDGECTVGVRPEAITLSEQGEESQRCTIKHVAYMGPQYEVTVDWHGQELLL 320

                        330       340
                 ....*....|....*....|....*...
gi 757596975 319 QINATQLQPTVGENLYLQIHPYGMFILE 346
Cdd:PRK11432 321 QVNATQLQPDLGEHYYLEIHPYGMFLLA 348
 
Name Accession Description Interval E-value
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
1-346 0e+00

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 754.63  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHNFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDI 80
Cdd:PRK11432   1 MTQKNFVVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQRDI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 CMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:PRK11432  81 CMVFQSYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDA 240
Cdd:PRK11432 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRFMASFMGDA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 241 NIFPATLTHDSVNIFNYHLPRPAQLATD--NTEITVGVRPEAITLSLQGDDSQRCTVTHVAYMGPQYEVTVDWHGQSMLL 318
Cdd:PRK11432 241 NIFPATLSGDYVDIYGYRLPRPAAFAFNlpDGECTVGVRPEAITLSEQGEESQRCTIKHVAYMGPQYEVTVDWHGQELLL 320

                        330       340
                 ....*....|....*....|....*...
gi 757596975 319 QINATQLQPTVGENLYLQIHPYGMFILE 346
Cdd:PRK11432 321 QVNATQLQPDLGEHYYLEIHPYGMFLLA 348
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 6-346 0e+00

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 505.79  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   6 FVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQ 85
Cdd:COG3842    5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVGMVFQ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:COG3842   85 DYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEPLS 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDANIFPA 245
Cdd:COG3842  165 ALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEANLLPG 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 246 TLTH---DSVNIFNYHLPRPAQLA-TDNTEITVGVRPEAITLSLQGDDSQ-RCTVTHVAYMGPQYEVTVDW-HGQSMLLQ 319
Cdd:COG3842  245 TVLGdegGGVRTGGRTLEVPADAGlAAGGPVTVAIRPEDIRLSPEGPENGlPGTVEDVVFLGSHVRYRVRLgDGQELVVR 324

                        330       340
                 ....*....|....*....|....*...
gi 757596975 320 I-NATQLQPTVGENLYLQIHPYGMFILE 346
Cdd:COG3842  325 VpNRAALPLEPGDRVGLSWDPEDVVVLP 352
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 6-337 9.52e-127

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 367.05  E-value: 9.52e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    6 FVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQ 85
Cdd:TIGR03265   4 YLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRLPPQKRDYGIVFQ 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:TIGR03265  84 SYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLLDEPLS 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDANIFPA 245
Cdd:TIGR03265 164 ALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGEVNWLPG 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  246 T-LTHDSVNIFNYHLPRPAQLATDNTEITVGVRPEAITLSLQGDDSQR--CTVTHVAYMGPQYEVTV---DWHGQSMLLQ 319
Cdd:TIGR03265 244 TrGGGSRARVGGLTLACAPGLAQPGASVRLAVRPEDIRVSPAGNAANLllARVEDMEFLGAFYRLRLrleGLPGQALVAD 323

                         330       340
                  ....*....|....*....|.
gi 757596975  320 INATQLQPT---VGENLYLQI 337
Cdd:TIGR03265 324 VSASEVERLgirAGQPIWIEL 344
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 7-238 4.29e-124

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 355.78  E-value: 4.29e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQS 86
Cdd:cd03300    1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRPVNTVFQN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:cd03300   81 YALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 167 LDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMG 238
Cdd:cd03300  161 LDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
ABC_arch_GlcV NF040933
glucose ABC transporter ATP-binding protein GlcV;
7-311 1.15e-99

glucose ABC transporter ATP-binding protein GlcV;


Pssm-ID: 468866 [Multi-domain]  Cd Length: 357  Bit Score: 298.45  E-value: 1.15e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFG---TNTV-IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD--RSI---QQ 77
Cdd:NF040933   3 VRVENVTKIFKkgkKEVVaLDNVNLEIKSGEFFGILGPSGHGKTTFLRIIAGLEVPTDGEIYFDDKLVASpgKIIvppED 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RDICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:NF040933  83 RNIGMVFQNWALYPNMTVFDNIAFPLKIKKVPKDEIEKKVKEVAEILGISEVLDRYPRELSGGQQQRVALARALVKNPQV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFM 237
Cdd:NF040933 163 LLLDEPFSNLDARIRDSARALVKKIQRELKITTIIVSHDPADIFSLADRAGVINNGKFQQVGKPEEIYDNPANIFVARLI 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 238 GDANIFPATLTHDSVNIFN-YHLPRPAQLAtDNTEITVGVRPEAITLSLQGDDS-------QRCTVTHVAYMGPQYEVTV 309
Cdd:NF040933 243 GDINLLEGKVEEEGLVDGNdLKIPLPNPKL-EAGEVIIGIRPEDIDISESDMRLppgfvevGKGRVKVSSYAGGVFRVVV 321


                 ..
gi 757596975 310 DW 311
Cdd:NF040933 322 SP 323
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
22-310 8.28e-87

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 265.40  E-value: 8.28e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQSYALFPHMSLGDNVGY 101
Cdd:NF040840  16 LRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLPPEKRGIAYVYQNYMLFPHKTVFENIAF 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 102 GLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRE 181
Cdd:NF040840  96 GLKLRKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALDVQTRDELIREMKR 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 182 LQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDANIFPATLTHDSVNIFnyhlpr 261
Cdd:NF040840 176 WHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVGFENIIEGVAEKGGEGTI------ 249

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757596975 262 paqLATDNTEIT----------VGVRPEAITLSLQGDDSQ-----RCTVTHVAYMGPQYEVTVD 310
Cdd:NF040840 250 ---LDTGNIKIElpeekkgkvrIGIRPEDITISTEKVKTSarnefKGKVEEIEDLGPLVKLTLD 310
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 22-165 1.51e-53

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 173.22  E-value: 1.51e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMVFQSYALFPHMSLGDNV 99
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSlrKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  100 GYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVD----QISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRPVGerpgTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
9-215 1.90e-46

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 157.19  E-value: 1.90e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   9 LKNVTKRFGTNT----VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRD----- 79
Cdd:NF038007   4 MQNAEKCYITKTiktkVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVTNLSYSQKIilrre 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 -ICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVL 158
Cdd:NF038007  84 lIGYIFQSFNLIPHLSIFDNVALPLKYRGVAKKERIERVNQVLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPALL 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 159 LFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQsEAFAVSDMVLVMNKGKI 215
Cdd:NF038007 164 LADEPTGNLDSKNARAVLQQLKYINQK-GTTIIMVTHSD-EASTYGNRIINMKDGKL 218
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
15-200 1.47e-32

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 120.03  E-value: 1.47e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  15 RFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEdvtdrsiqqRDICMVFQSYAL---FP 91
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGG---------ARVAYVPQRSEVpdsLP 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  92 hMSLGDNVGYGL----KMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNL 167
Cdd:NF040873  72 -LTVRDLVAMGRwarrGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGL 150

                        170       180       190
                 ....*....|....*....|....*....|...
gi 757596975 168 DANLRRSMREKIRELQQQfNITSLYVTHDQSEA 200
Cdd:NF040873 151 DAESRERIIALLAEEHAR-GATVVVVTHDLELV 182
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
7-227 4.96e-27

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 112.14  E-value: 4.96e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSiQQRDICmvfQS 86
Cdd:NF033858   2 ARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADAR-HRRAVC---PR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YA---------LFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:NF033858  78 IAympqglgknLYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDL 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTH---DQSEAFavsDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:NF033858 158 LILDEPTTGVDPLSRRQFWELIDRIRAERPGMSVLVATaymEEAERF---DWLVAMDAGRVLATGTPAELLAR 227
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
7-227 2.44e-25

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 107.13  E-value: 2.44e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRD-ICMVFQ 85
Cdd:NF033858 267 IEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGDIATRRrVGYMSQ 346

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:NF033858 347 AFSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTS 426

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAfAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:NF033858 427 GVDPVARDMFWRLLIELSREDGVTIFISTHFMNEA-ERCDRISLMHAGRVLASDTPAALVAA 487
GguA NF040905
sugar ABC transporter ATP-binding protein;
8-214 2.52e-17

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 82.53  E-value: 2.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLeKPT---EGRMFIDGEDVTDRSI---QQRDIC 81
Cdd:NF040905   3 EMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGV-YPHgsyEGEILFDGEVCRFKDIrdsEALGIV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSYALFPHMSLGDNVgyglkMLGLPKA--------EIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALIL 153
Cdd:NF040905  82 IIHQELALIPYLSIAENI-----FLGNERAkrgvidwnETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSK 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 154 KPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGK 214
Cdd:NF040905 157 DVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGR 216
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
5-231 2.40e-15

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 75.93  E-value: 2.40e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   5 NFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVlRLVAGLEKPTEGR------MFIDGEDVTDRSIQQR 78
Cdd:NF000106  12 NAVEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRrpwrf*TWCANRRALRRTIG*H 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 DICMVFQSYALfphmSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVL 158
Cdd:NF000106  91 RPVR*GRRESF----SGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVL 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 159 LFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASR 231
Cdd:NF000106 167 YLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVGGR 238
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 31-196 4.45e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 54.69  E-value: 4.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    31 QGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMF-IDGEDVTDRSIQQRDICMVFQSYAlfphmslgdnvgyglkmlglp 109
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIyIDGEDILEEVLDQLLLIIVGGKKA--------------------- 59

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   110 kaeirkrvdealelvdlagfadrfvdQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIR-----ELQQ 184
Cdd:smart00382  60 --------------------------SGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrlllLLKS 113

                          170
                   ....*....|..
gi 757596975   185 QFNITSLYVTHD 196
Cdd:smart00382 114 EKNLTVILTTND 125
GguA NF040905
sugar ABC transporter ATP-binding protein;
21-163 3.12e-04

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 42.47  E-value: 3.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  21 VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLE--KPTEGRMFIDGEDVTDRSIQQ---RDICMVFQ---SYALfph 92
Cdd:NF040905 275 VVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGRSygRNISGTVFKDGKEVDVSTVSDaidAGLAYVTEdrkGYGL--- 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  93 mSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRF------VDQI----SGGQQQRVALARALILKPKVLLFDE 162
Cdd:NF040905 352 -NLIDDIKRNITLANLGKVSRRGVIDENEEIKVAEEYRKKMniktpsVFQKvgnlSGGNQQKVVLSKWLFTDPDVLILDE 430


                 .
gi 757596975 163 P 163
Cdd:NF040905 431 P 431
 
Name Accession Description Interval E-value
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
1-346 0e+00

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 754.63  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHNFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDI 80
Cdd:PRK11432   1 MTQKNFVVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQRDI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 CMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:PRK11432  81 CMVFQSYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDA 240
Cdd:PRK11432 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRFMASFMGDA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 241 NIFPATLTHDSVNIFNYHLPRPAQLATD--NTEITVGVRPEAITLSLQGDDSQRCTVTHVAYMGPQYEVTVDWHGQSMLL 318
Cdd:PRK11432 241 NIFPATLSGDYVDIYGYRLPRPAAFAFNlpDGECTVGVRPEAITLSEQGEESQRCTIKHVAYMGPQYEVTVDWHGQELLL 320

                        330       340
                 ....*....|....*....|....*...
gi 757596975 319 QINATQLQPTVGENLYLQIHPYGMFILE 346
Cdd:PRK11432 321 QVNATQLQPDLGEHYYLEIHPYGMFLLA 348
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 6-346 0e+00

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 505.79  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   6 FVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQ 85
Cdd:COG3842    5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVGMVFQ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:COG3842   85 DYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEPLS 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDANIFPA 245
Cdd:COG3842  165 ALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEANLLPG 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 246 TLTH---DSVNIFNYHLPRPAQLA-TDNTEITVGVRPEAITLSLQGDDSQ-RCTVTHVAYMGPQYEVTVDW-HGQSMLLQ 319
Cdd:COG3842  245 TVLGdegGGVRTGGRTLEVPADAGlAAGGPVTVAIRPEDIRLSPEGPENGlPGTVEDVVFLGSHVRYRVRLgDGQELVVR 324

                        330       340
                 ....*....|....*....|....*...
gi 757596975 320 I-NATQLQPTVGENLYLQIHPYGMFILE 346
Cdd:COG3842  325 VpNRAALPLEPGDRVGLSWDPEDVVVLP 352
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 7-339 1.87e-167

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 470.32  E-value: 1.87e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQS 86
Cdd:COG3839    4 LELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKDRNIAMVFQS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:COG3839   84 YALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDEPLSN 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 167 LDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGD--ANIFP 244
Cdd:COG3839  164 LDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEELYDRPANLFVAGFIGSppMNLLP 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 245 ATLTHDSVNIFNYHLPRPAQLAT-DNTEITVGVRPEAITLSLQGDDSQRCTVTHVAYMGPQYEVTVDWHGQSMLLQINAt 323
Cdd:COG3839  244 GTVEGGGVRLGGVRLPLPAALAAaAGGEVTLGIRPEHLRLADEGDGGLEATVEVVEPLGSETLVHVRLGGQELVARVPG- 322

                        330
                 ....*....|....*.
gi 757596975 324 QLQPTVGENLYLQIHP 339
Cdd:COG3839  323 DTRLRPGDTVRLAFDP 338
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 7-344 2.94e-145

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 413.77  E-value: 2.94e-145
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDV-TDRSIQQRDICMVFQ 85
Cdd:COG1118    3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLfTNLPPRERRVGFVFQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:COG1118   83 HYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEPFG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDANIFPA 245
Cdd:COG1118  163 ALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPATPFVARFLGCVNVLRG 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 246 TLTHDSVNIFNyhLPRPAQLATDNTEITVGVRPEAITLSLQGDDSQ--RCTVTHVAYMGPQYEVTV---DWHGQSMLLQI 320
Cdd:COG1118  243 RVIGGQLEADG--LTLPVAEPLPDGPAVAGVRPHDIEVSREPEGENtfPATVARVSELGPEVRVELkleDGEGQPLEAEV 320

                        330       340
                 ....*....|....*....|....*..
gi 757596975 321 N---ATQLQPTVGENLYLQIHPYGMFI 344
Cdd:COG1118  321 TkeaWAELGLAPGDPVYLRPRPARVFL 347
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1-291 4.67e-127

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 368.89  E-value: 4.67e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHNFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDI 80
Cdd:PRK09452   9 SSLSPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAENRHV 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 CMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:PRK09452  89 NTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDA 240
Cdd:PRK09452 169 DESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIGEI 248

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 241 NIFPATLT--HDSVNI--------FNYHLPRPAQLatdNTEITVGVRPEAITLSLQGDDSQ 291
Cdd:PRK09452 249 NIFDATVIerLDEQRVranvegreCNIYVNFAVEP---GQKLHVLLRPEDLRVEEINDDEH 306
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 6-337 9.52e-127

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 367.05  E-value: 9.52e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    6 FVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQ 85
Cdd:TIGR03265   4 YLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRLPPQKRDYGIVFQ 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:TIGR03265  84 SYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLLDEPLS 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDANIFPA 245
Cdd:TIGR03265 164 ALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGEVNWLPG 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  246 T-LTHDSVNIFNYHLPRPAQLATDNTEITVGVRPEAITLSLQGDDSQR--CTVTHVAYMGPQYEVTV---DWHGQSMLLQ 319
Cdd:TIGR03265 244 TrGGGSRARVGGLTLACAPGLAQPGASVRLAVRPEDIRVSPAGNAANLllARVEDMEFLGAFYRLRLrleGLPGQALVAD 323

                         330       340
                  ....*....|....*....|.
gi 757596975  320 INATQLQPT---VGENLYLQI 337
Cdd:TIGR03265 324 VSASEVERLgirAGQPIWIEL 344
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 7-238 4.29e-124

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 355.78  E-value: 4.29e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQS 86
Cdd:cd03300    1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRPVNTVFQN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:cd03300   81 YALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 167 LDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMG 238
Cdd:cd03300  161 LDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 7-219 8.73e-122

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 349.13  E-value: 8.73e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQS 86
Cdd:cd03259    1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPERRNIGMVFQD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:cd03259   81 YALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSA 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 757596975 167 LDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:cd03259  161 LDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
7-340 3.34e-118

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 345.68  E-value: 3.34e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT-VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQ 85
Cdd:PRK11650   4 LKLQAVRKSYDGKTqVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPADRDIAMVFQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:PRK11650  84 NYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFLFDEPLS 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDA--NIF 243
Cdd:PRK11650 164 NLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEVYEKPASTFVASFIGSPamNLL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 244 PATLT-HDSVNIFNYH--LPRPAQLATDNTE-ITVGVRPEAITLSlQGDDSQRCTVTHVAYMGPQYEVTVDWHGQSMLLQ 319
Cdd:PRK11650 244 DGRVSaDGAAFELAGGiaLPLGGGYRQYAGRkLTLGIRPEHIALS-SAEGGVPLTVDTVELLGADNLAHGRWGGQPLVVR 322

                        330       340
                 ....*....|....*....|....*.
gi 757596975 320 InATQLQPTVGENLYL-----QIHPY 340
Cdd:PRK11650 323 L-PHQERPAAGSTLWLhlpanQLHLF 347
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 7-239 8.40e-114

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 330.07  E-value: 8.40e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQS 86
Cdd:cd03296    3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQERNVGFVFQH 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKM----LGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDE 162
Cdd:cd03296   83 YALFRHMTVFDNVAFGLRVkprsERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDE 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 163 PLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGD 239
Cdd:cd03296  163 PFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSFLGE 239
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 7-219 2.90e-108

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 314.96  E-value: 2.90e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQS 86
Cdd:cd03301    1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKDRDIAMVFQN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:cd03301   81 YALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSN 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 757596975 167 LDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:cd03301  161 LDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
3a0106s01 TIGR00968
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
 7-242 2.96e-106

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]


Pssm-ID: 130041 [Multi-domain]  Cd Length: 237  Bit Score: 310.96  E-value: 2.96e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQS 86
Cdd:TIGR00968   1 IEIANISKRFGSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQPDSGRIRLNGQDATRVHARDRKIGFVFQH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   87 YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:TIGR00968  81 YALFKHLTVRDNIAFGLEIRKHPKAKIKARVEELLELVQLEGLGDRYPNQLSGGQRQRVALARALAVEPQVLLLDEPFGA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975  167 LDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDANI 242
Cdd:TIGR00968 161 LDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFVMSFLGEVNV 236
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 37-339 1.80e-105

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 312.12  E-value: 1.80e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   37 LLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKR 116
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPPHLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPRAEIKPR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  117 VDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHD 196
Cdd:TIGR01187  81 VLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITFVFVTHD 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  197 QSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDANIFPATLTH--DSVNIFNYHLPRPAQLATD-----N 269
Cdd:TIGR01187 161 QEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINVFEATVIErkSEQVVLAGVEGRRCDIYTDvpvekD 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975  270 TEITVGVRPEAITL----SLQGDDSQRCTVTHVAYMGPQYEVTVDW-HGQSMLLQI----NATQLQPTVGENLYLQIHP 339
Cdd:TIGR01187 241 QPLHVVLRPEKIVIeeedEANSSNAIIGHVIDITYLGMTLEVHVRLeTGQKVLVSEffneDDPHMSPSIGDRVGLTWHP 319
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
7-335 6.80e-102

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 303.93  E-value: 6.80e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQS 86
Cdd:PRK10851   3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVFQH 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLglPK------AEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:PRK10851  83 YALFRHMTVFDNIAFGLTVL--PRrerpnaAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDA 240
Cdd:PRK10851 161 DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFMGEV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 241 NIFPATLTHDSVNIFNYHLPRPAQLATDNtEITVGVRPEAITLSLQGddSQRC----TVTHVAYMGPQYEVTV---DWHG 313
Cdd:PRK10851 241 NRLQGTIRGGQFHVGAHRWPLGYTPAYQG-PVDLFLRPWEVDISRRT--SLDSplpvQVLEVSPKGHYWQLVVqplGWYN 317

                        330       340
                 ....*....|....*....|..
gi 757596975 314 QSMLLQINATQLQPTVGENLYL 335
Cdd:PRK10851 318 EPLTVVMHGDIDAPQRGERLFV 339
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-213 4.22e-100

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 295.85  E-value: 4.22e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHN-FVELKNVTKRF----GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSi 75
Cdd:COG1116    1 MSAAApALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPG- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  76 qqRDICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKP 155
Cdd:COG1116   80 --PDRGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDP 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 156 KVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKG 213
Cdd:COG1116  158 EVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVLSAR 215
ABC_arch_GlcV NF040933
glucose ABC transporter ATP-binding protein GlcV;
7-311 1.15e-99

glucose ABC transporter ATP-binding protein GlcV;


Pssm-ID: 468866 [Multi-domain]  Cd Length: 357  Bit Score: 298.45  E-value: 1.15e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFG---TNTV-IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD--RSI---QQ 77
Cdd:NF040933   3 VRVENVTKIFKkgkKEVVaLDNVNLEIKSGEFFGILGPSGHGKTTFLRIIAGLEVPTDGEIYFDDKLVASpgKIIvppED 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RDICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:NF040933  83 RNIGMVFQNWALYPNMTVFDNIAFPLKIKKVPKDEIEKKVKEVAEILGISEVLDRYPRELSGGQQQRVALARALVKNPQV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFM 237
Cdd:NF040933 163 LLLDEPFSNLDARIRDSARALVKKIQRELKITTIIVSHDPADIFSLADRAGVINNGKFQQVGKPEEIYDNPANIFVARLI 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 238 GDANIFPATLTHDSVNIFN-YHLPRPAQLAtDNTEITVGVRPEAITLSLQGDDS-------QRCTVTHVAYMGPQYEVTV 309
Cdd:NF040933 243 GDINLLEGKVEEEGLVDGNdLKIPLPNPKL-EAGEVIIGIRPEDIDISESDMRLppgfvevGKGRVKVSSYAGGVFRVVV 321


                 ..
gi 757596975 310 DW 311
Cdd:NF040933 322 SP 323
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
7-335 2.31e-94

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 285.58  E-value: 2.31e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQS 86
Cdd:PRK11607  20 LEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQRPINMMFQS 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:PRK11607 100 YALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGA 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 167 LDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDANIFPAT 246
Cdd:PRK11607 180 LDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGV 259

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 247 LTH---DSVNIFNYHLPRPAQLAT-----DNTEITVGVRPEAITLSLQ----GDDSQRCTVTHVAYMGpqyEVTVdWHGQ 314
Cdd:PRK11607 260 LKErqeDGLVIDSPGLVHPLKVDAdasvvDNVPVHVALRPEKIMLCEEppadGCNFAVGEVIHIAYLG---DLSI-YHVR 335

                        330       340       350
                 ....*....|....*....|....*....|
gi 757596975 315 SMLLQINATQLQ---------PTVGENLYL 335
Cdd:PRK11607 336 LKSGQMISAQLQnahryrkglPTWGDEVRL 365
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 8-238 2.56e-93

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 280.44  E-value: 2.56e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRF-GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMVF 84
Cdd:COG1125    3 EFENVTKRYpDGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRDLDPVElrRRIGYVI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDL--AGFADRFVDQISGGQQQRVALARALILKPKVLLFDE 162
Cdd:COG1125   83 QQIGLFPHMTVAENIATVPRLLGWDKERIRARVDELLELVGLdpEEYRDRYPHELSGGQQQRVGVARALAADPPILLMDE 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 163 PLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMG 238
Cdd:COG1125  163 PFGALDPITREQLQDELLRLQRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILANPANDFVADFVG 238
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
7-302 2.78e-93

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 282.69  E-value: 2.78e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQS 86
Cdd:PRK11000   4 VTLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAERGVGMVFQS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:PRK11000  84 YALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSN 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 167 LDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDA--NIFP 244
Cdd:PRK11000 164 LDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPANRFVAGFIGSPkmNFLP 243

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 245 ATLTH---DSVNI-----FNYHLPRPAQLATDNTEITVGVRPEAITLSLQGDDSQRCTVTHVAYMG 302
Cdd:PRK11000 244 VKVTAtaiEQVQVelpnrQQVWLPVEGRGVQVGANMSLGIRPEHLLPSDIADVTLEGEVQVVEQLG 309
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 7-215 5.24e-93

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 276.27  E-value: 5.24e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSiqqRDICM 82
Cdd:cd03293    1 LEVRNVSKTYGGGggavTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPG---PDRGY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDE 162
Cdd:cd03293   78 VFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDE 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 163 PLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNK--GKI 215
Cdd:cd03293  158 PFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLSArpGRI 212
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 5-224 2.63e-89

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 267.62  E-value: 2.63e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   5 NFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRD----- 79
Cdd:COG1127    4 PMIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELYelrrr 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 ICMVFQSYALFPHMSLGDNVGYGLKML-GLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVL 158
Cdd:COG1127   84 IGMLFQGGALFDSLTVFENVAFPLREHtDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPEIL 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 159 LFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:COG1127  164 LYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEEL 229
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 7-238 4.65e-87

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 262.24  E-value: 4.65e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF-GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMV 83
Cdd:cd03295    1 IEFENVTKRYgGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVElrRKIGYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDL--AGFADRFVDQISGGQQQRVALARALILKPKVLLFD 161
Cdd:cd03295   81 IQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLdpAEFADRYPHELSGGQQQRVGVARALAADPPLLLMD 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 162 EPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMG 238
Cdd:cd03295  161 EPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEFVG 237
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
22-310 8.28e-87

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 265.40  E-value: 8.28e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQSYALFPHMSLGDNVGY 101
Cdd:NF040840  16 LRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLPPEKRGIAYVYQNYMLFPHKTVFENIAF 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 102 GLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRE 181
Cdd:NF040840  96 GLKLRKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALDVQTRDELIREMKR 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 182 LQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDANIFPATLTHDSVNIFnyhlpr 261
Cdd:NF040840 176 WHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVGFENIIEGVAEKGGEGTI------ 249

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757596975 262 paqLATDNTEIT----------VGVRPEAITLSLQGDDSQ-----RCTVTHVAYMGPQYEVTVD 310
Cdd:NF040840 250 ---LDTGNIKIElpeekkgkvrIGIRPEDITISTEKVKTSarnefKGKVEEIEDLGPLVKLTLD 310
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 7-242 6.05e-84

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 253.80  E-value: 6.05e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGtNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQS 86
Cdd:cd03299    1 LKVENLSKDWK-EFKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEKRDISYVPQN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:cd03299   80 YALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSA 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 167 LDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDANI 242
Cdd:cd03299  160 LDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFLGFNNI 235
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 7-230 1.49e-82

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 250.30  E-value: 1.49e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ----QRDICM 82
Cdd:COG1126    2 IEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSKKDinklRRKVGM 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFPHMSLGDNVGYGL-KMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFD 161
Cdd:COG1126   82 VFQQFNLFPHLTVLENVTLAPiKVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLFD 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975 162 EPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPAS 230
Cdd:COG1126  162 EPTSALDPELVGEVLDVMRDLAKE-GMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFENPQH 229
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 7-228 1.29e-80

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 254.44  E-value: 1.29e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN-----TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ---- 77
Cdd:COG1123  261 LEVRNLSKRYPVRgkggvRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSlrel 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 -RDICMVFQ--SYALFPHMSLGDNVGYGLKMLG-LPKAEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARALI 152
Cdd:COG1123  341 rRRVQMVFQdpYSSLNPRMTVGDIIAEPLRLHGlLSRAERRERVAELLERVGLpPDLADRYPHELSGGQRQRVAIARALA 420

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:COG1123  421 LEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANP 496
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
7-227 7.58e-80

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 243.43  E-value: 7.58e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ-QRDICMVFQ 85
Cdd:COG1131    1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEvRRRIGYVPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:COG1131   81 EPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTS 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 166 NLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:COG1131  161 GLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKAR 221
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 7-224 1.46e-79

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 242.79  E-value: 1.46e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ-----RDIC 81
Cdd:cd03261    1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAElyrlrRRMG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSYALFPHMSLGDNVGYGLKMLG-LPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:cd03261   81 MLFQSGALFDSLTVFENVAFPLREHTrLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLY 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757596975 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:cd03261  161 DEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224
ProV COG4175
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 7-241 2.15e-79

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443334 [Multi-domain]  Cd Length: 389  Bit Score: 247.71  E-value: 2.15e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN-----------------------TV-IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGR 62
Cdd:COG4175    4 IEVRNLYKIFGKRperalklldqgkskdeilektgqTVgVNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPTAGE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  63 MFIDGEDVTD------RSIQQRDICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQ 136
Cdd:COG4175   84 VLIDGEDITKlskkelRELRRKKMSMVFQHFALLPHRTVLENVAFGLEIQGVPKAERRERAREALELVGLAGWEDSYPDE 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 137 ISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIM 216
Cdd:COG4175  164 LSGGMQQRVGLARALATDPDILLMDEAFSALDPLIRREMQDELLELQAKLKKTIVFITHDLDEALRLGDRIAIMKDGRIV 243

                        250       260
                 ....*....|....*....|....*
gi 757596975 217 QLGSPQELYRQPASRFMASFMGDAN 241
Cdd:COG4175  244 QIGTPEEILTNPANDYVADFVEDVD 268
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 7-228 2.23e-78

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 239.54  E-value: 2.23e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF-GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMV 83
Cdd:COG1122    1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRElrRKVGLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQS--YALFpHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFD 161
Cdd:COG1122   81 FQNpdDQLF-APTVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLD 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 162 EPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:COG1122  160 EPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDY 225
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 7-214 1.30e-77

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 235.54  E-value: 1.30e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD----RSIQQRDICM 82
Cdd:cd03229    1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDledeLPPLRRRIGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFPHMSLGDNVGYGLkmlglpkaeirkrvdealelvdlagfadrfvdqiSGGQQQRVALARALILKPKVLLFDE 162
Cdd:cd03229   81 VFQDFALFPHLTVLENIALGL----------------------------------SGGQQQRVALARALAMDPDVLLLDE 126

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 757596975 163 PLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGK 214
Cdd:cd03229  127 PTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 7-215 1.29e-75

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 232.00  E-value: 1.29e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRD--- 79
Cdd:cd03255    1 IELKNLSKTYGGGgekvQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAafr 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 ---ICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPK 156
Cdd:cd03255   81 rrhIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975 157 VLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAvSDMVLVMNKGKI 215
Cdd:cd03255  161 IILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEY-ADRIIELRDGKI 218
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 7-239 1.35e-75

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 233.69  E-value: 1.35e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN-----------------------TV-IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGR 62
Cdd:cd03294    1 IKIKGLYKIFGKNpqkafkllakgkskeeilkktgqTVgVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  63 MFIDGEDVTD------RSIQQRDICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQ 136
Cdd:cd03294   81 VLIDGQDIAAmsrkelRELRRKKISMVFQSFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 137 ISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIM 216
Cdd:cd03294  161 LSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLV 240

                        250       260
                 ....*....|....*....|...
gi 757596975 217 QLGSPQELYRQPASRFMASFMGD 239
Cdd:cd03294  241 QVGTPEEILTNPANDYVREFFRG 263
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
7-215 5.61e-74

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 228.00  E-value: 5.61e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRD--- 79
Cdd:COG1136    5 LELRNLTKSYGTGegevTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELArlr 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 ---ICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPK 156
Cdd:COG1136   85 rrhIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRPK 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975 157 VLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQsEAFAVSDMVLVMNKGKI 215
Cdd:COG1136  165 LILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDP-ELAARADRVIRLRDGRI 222
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 7-230 5.71e-73

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 226.22  E-value: 5.71e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGT----NTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDI 80
Cdd:COG1124    2 LEVRNLSVSYGQggrrVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAfrRRV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 CMVFQSY--ALFPHMSLGDNVGYGLKMLGLPkaEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:COG1124   82 QMVFQDPyaSLHPRHTVDRILAEPLRIHGLP--DREERIAELLEQVGLpPSFLDRYPHQLSGGQRQRVAIARALILEPEL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPAS 230
Cdd:COG1124  160 LLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGPKH 232
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 11-337 3.01e-72

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 228.06  E-value: 3.01e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  11 NVTKRFGTNTVidDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRS------IQQRDICMVF 84
Cdd:COG4148    6 DFRLRRGGFTL--DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDSArgiflpPHRRRIGYVF 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMSLGDNVGYGLKMLglPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPL 164
Cdd:COG4148   84 QEARLFPHLSVRGNLLYGRKRA--PRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 165 SNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDANIFP 244
Cdd:COG4148  162 AALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPDLLPLAGGEEAGSVLE 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 245 ATLT-HDSvnifNYHLPR----------PAQLATDNTEITVGVRPEAITLSLQ--GDDSQR----CTVTHV-AYMGPQYE 306
Cdd:COG4148  242 ATVAaHDP----DYGLTRlalgggrlwvPRLDLPPGTRVRVRIRARDVSLALEppEGSSILnilpGRVVEIePADGGQVL 317

                        330       340       350
                 ....*....|....*....|....*....|....
gi 757596975 307 VTVDWHGQSMLLQI---NATQLQPTVGENLYLQI 337
Cdd:COG4148  318 VRLDLGGQTLLARItrrSADELGLAPGQTVYAQI 351
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 7-228 4.79e-72

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 223.61  E-value: 4.79e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRS-----IQQ 77
Cdd:cd03258    2 IELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSgkelrKAR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RDICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:cd03258   82 RRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKV 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:cd03258  162 LLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFANP 232
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 7-215 1.02e-71

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 222.02  E-value: 1.02e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ----QRDICM 82
Cdd:cd03262    1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNinelRQKVGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFPHMSLGDNVGYGL-KMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFD 161
Cdd:cd03262   81 VFQQFNLFPHLTVLENITLAPiKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFD 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 757596975 162 EPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:cd03262  161 EPTSALDPELVGEVLDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFMDDGRI 213
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
8-238 1.57e-71

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 221.94  E-value: 1.57e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVidDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQSY 87
Cdd:COG3840    3 RLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAERPVSMLFQEN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  88 ALFPHMSLGDNVGYGLKmlglPK----AEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEP 163
Cdd:COG3840   81 NLFPHLTVAQNIGLGLR----PGlkltAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEP 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 164 LSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMG 238
Cdd:COG3840  157 FSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYLG 231
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
7-236 3.93e-71

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 224.57  E-value: 3.93e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ----- 77
Cdd:COG1135    2 IELENLSKTFPTKggpvTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERElraar 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RDICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:COG1135   82 RKIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPKV 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASF 236
Cdd:COG1135  162 LLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFANPQSELTRRF 240
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 8-214 1.26e-70

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 218.88  E-value: 1.26e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNT--VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMV 83
Cdd:cd03225    1 ELKNLSFSYPDGArpALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKElrRKVGLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQsyalFP-HMSLGDNVG----YGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVL 158
Cdd:cd03225   81 FQ----NPdDQFFGPTVEeevaFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDIL 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 159 LFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGK 214
Cdd:cd03225  157 LLDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
7-215 2.85e-69

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 216.07  E-value: 2.85e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN-TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD---RSIQQ--RDI 80
Cdd:COG2884    2 IRFENVSKRYPGGrEALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRlkrREIPYlrRRI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 CMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:COG2884   82 GVVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLA 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 161 DEPLSNLDanlrRSMREKIRELQQQFN---ITSLYVTHDQSeafAVSDM---VLVMNKGKI 215
Cdd:COG2884  162 DEPTGNLD----PETSWEIMELLEEINrrgTTVLIATHDLE---LVDRMpkrVLELEDGRL 215
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
7-237 8.29e-69

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 215.34  E-value: 8.29e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDI----CM 82
Cdd:PRK09493   2 IEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERLIrqeaGM 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFPHMSLGDNVGYG-LKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFD 161
Cdd:PRK09493  82 VFQQFYLFPHLTALENVMFGpLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFD 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 162 EPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFM 237
Cdd:PRK09493 162 EPTSALDPELRHEVLKVMQDLAEE-GMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQEFL 236
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 7-224 1.51e-67

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 212.60  E-value: 1.51e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMVF 84
Cdd:COG1120    2 LEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRElaRRIAYVP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMSLGDNVGYG----LKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:COG1120   82 QEPPAPFGLTVRELVALGryphLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLL 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757596975 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:COG1120  162 DEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEV 225
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 7-219 1.83e-65

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 206.59  E-value: 1.83e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF----GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD-----RSIQQ 77
Cdd:cd03257    2 LEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKlsrrlRKIRR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RDICMVFQSY--ALFPHMSLGDNVGYGLKMLGLP--KAEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARALI 152
Cdd:cd03257   82 KEIQMVFQDPmsSLNPRMTIGEQIAEPLRIHGKLskKEARKEAVLLLLVGVGLpEEVLNRYPHELSGGQRQRVAIARALA 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:cd03257  162 LNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 8-223 2.31e-65

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 205.41  E-value: 2.31e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKP---TEGRMFIDGEDVTDRSIQQRDICMVF 84
Cdd:COG4136    3 SLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLLNGRRLTALPAEQRRIGILF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMSLGDNVGYGLKMlGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPL 164
Cdd:COG4136   83 QDDLLFPHLSVGENLAFALPP-TIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPF 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975 165 SNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVsdmvlvmnkGKIMQLGSPQE 223
Cdd:COG4136  162 SKLDAALRAQFREFVFEQIRQRGIPALLVTHDEEDAPAA---------GRVLDLGNWQH 211
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 14-219 4.39e-65

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 204.84  E-value: 4.39e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  14 KRFGTNTVidDLSLSIPqGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSI------QQRDICMVFQSY 87
Cdd:cd03297    8 KRLPDFTL--KIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKkinlppQQRKIGLVFQQY 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  88 ALFPHMSLGDNVGYGLKmlGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNL 167
Cdd:cd03297   85 ALFPHLNVRENLAFGLK--RKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSAL 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 757596975 168 DANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:cd03297  163 DRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 8-227 6.12e-65

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 205.48  E-value: 6.12e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ-QRDICMVFQS 86
Cdd:COG4555    3 EVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREaRRQIGVLPDE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:COG4555   83 RGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNG 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 167 LDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:COG4555  163 LDVMARRLLREILRALKKE-GKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREE 222
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
8-208 2.44e-64

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 204.71  E-value: 2.44e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFG----TNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT----DRSIqqrd 79
Cdd:COG4525    5 TVRHVSVRYPgggqPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTgpgaDRGV---- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 icmVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLL 159
Cdd:COG4525   81 ---VFQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLL 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 757596975 160 FDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEA-FAVSDMVL 208
Cdd:COG4525  158 MDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVEEAlFLATRLVV 207
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 7-227 3.15e-64

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 204.59  E-value: 3.15e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRF--GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRS----IQQRdI 80
Cdd:TIGR04520   1 IEVENVSFSYpeSEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLDEEnlweIRKK-V 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   81 CMVFQSyalfPhmslgDN----------VGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARA 150
Cdd:TIGR04520  80 GMVFQN----P-----DNqfvgatveddVAFGLENLGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGV 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975  151 LILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAfAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:TIGR04520 151 LAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEA-VLADRVIVMNKGKIVAEGTPREIFSQ 226
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 7-224 5.47e-64

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 202.41  E-value: 5.47e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEK-----PTEGRMFIDGEDVTDRSIQ----Q 77
Cdd:cd03260    1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDlipgaPDEGEVLLDGKDIYDLDVDvlelR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RDICMVFQSYALFPhMSLGDNVGYGLKMLG-LPKAEIRKRVDEALELVDLAG-FADR-FVDQISGGQQQRVALARALILK 154
Cdd:cd03260   81 RRVGMVFQKPNPFP-GSIYDNVAYGLRLHGiKLKEELDERVEEALRKAALWDeVKDRlHALGLSGGQQQRLCLARALANE 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 155 PKVLLFDEPLSNLDANLRRSMREKIRELQQQfnITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:cd03260  160 PEVLLLDEPTSALDPISTAKIEELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 1-229 2.37e-63

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 204.20  E-value: 2.37e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHNFVELKNVTKRF---------GTNTV--IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGED 69
Cdd:COG4608    2 AMAEPLLEVRDLKKHFpvrgglfgrTVGVVkaVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  70 VTDRSIQQ-----RDICMVFQ-SYA-LFPHMSLGDNVGYGLKMLGL-PKAEIRKRVDEALELVDL-AGFADRFVDQISGG 140
Cdd:COG4608   82 ITGLSGRElrplrRRMQMVFQdPYAsLNPRMTVGDIIAEPLRIHGLaSKAERRERVAELLELVGLrPEHADRYPHEFSGG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 141 QQQRVALARALILKPKVLLFDEPLSNLDAnlrrSMREKI----RELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIM 216
Cdd:COG4608  162 QRQRIGIARALALNPKLIVCDEPVSALDV----SIQAQVlnllEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIV 237

                        250
                 ....*....|...
gi 757596975 217 QLGSPQELYRQPA 229
Cdd:COG4608  238 EIAPRDELYARPL 250
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 8-229 2.59e-63

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 201.81  E-value: 2.59e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRS---IQQRDICMVF 84
Cdd:COG0411    6 EVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPphrIARLGIARTF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMSLGDNV----------GYGLKMLGLPK-----AEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALAR 149
Cdd:COG0411   86 QNPRLFPELTVLENVlvaaharlgrGLLAALLRLPRarreeREARERAEELLERVGLADRADEPAGNLSYGQQRRLEIAR 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 150 ALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPA 229
Cdd:COG0411  166 ALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTPAEVRADPR 245
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 7-224 3.67e-63

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 201.05  E-value: 3.67e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF-GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT---DRSIQQ--RDI 80
Cdd:COG3638    3 LELRNLSKRYpGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTalrGRALRRlrRRI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 CMVFQSYALFPHMSLGDNV-----GY--GLK-MLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALI 152
Cdd:COG3638   83 GMIFQQFNLVPRLSVLTNVlagrlGRtsTWRsLLGLFPPEDRERALEALERVGLADKAYQRADQLSGGQQQRVAIARALV 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 153 LKPKVLLFDEPLSNLD-ANLRRSMREkIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:COG3638  163 QEPKLILADEPVASLDpKTARQVMDL-LRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGRVVFDGPPAEL 234
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 7-224 8.72e-62

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 196.82  E-value: 8.72e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ-QRDICMVFQ 85
Cdd:cd03265    1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREvRRRIGIVFQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:cd03265   81 DLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTI 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975 166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:cd03265  161 GLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 9-215 2.47e-61

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 196.82  E-value: 2.47e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   9 LKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDrsiQQRDICMVFQSYA 88
Cdd:PRK11247  15 LNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAE---AREDTRLMFQDAR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  89 LFPHMSLGDNVGYGLKmlglpkAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLD 168
Cdd:PRK11247  92 LLPWKKVIDNVGLGLK------GQWRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALD 165

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 757596975 169 ANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:PRK11247 166 ALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
ectoine_ehuA TIGR03005
ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ...
 7-237 4.34e-61

ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding protein of a conserved four gene ABC transporter operon found next to ectoine unilization operons and ectoine biosynthesis operons. Ectoine is a compatible solute that protects enzymes from high osmolarity. It is released by some species in response to hypoosmotic shock, and it is taken up by a number of bacteria as a compatible solute or for consumption. This family shows strong sequence similiarity to a number of amino acid ABC transporter ATP-binding proteins.


Pssm-ID: 132050 [Multi-domain]  Cd Length: 252  Bit Score: 196.20  E-value: 4.34e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD-------------- 72
Cdd:TIGR03005   1 VRFSDVTKRFGILTVLDGLNFSVAAGEKVALIGPSGSGKSTILRILMTLEPIDEGQIQVEGEQLYHmpgrngplvpadek 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   73 --RSIQQRdICMVFQSYALFPHMSLGDNVGYG-LKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALAR 149
Cdd:TIGR03005  81 hlRQMRNK-IGMVFQSFNLFPHKTVLDNVTEApVLVLGMARAEAEKRAMELLDMVGLADKADHMPAQLSGGQQQRVAIAR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  150 ALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPA 229
Cdd:TIGR03005 160 ALAMRPKVMLFDEVTSALDPELVGEVLNVIRRLASEHDLTMLLVTHEMGFAREFADRVCFFDKGRIVEQGKPDEIFRQPK 239


                  ....*...
gi 757596975  230 SRFMASFM 237
Cdd:TIGR03005 240 EERTREFL 247
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 7-230 6.24e-61

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 203.21  E-value: 6.24e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF--GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPT---EGRMFIDGEDVTDRSIQQR--D 79
Cdd:COG1123    5 LEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEALRgrR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 ICMVFQS--YALFPhMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:COG1123   85 IGMVFQDpmTQLNP-VTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDL 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPAS 230
Cdd:COG1123  164 LIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQA 236
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-229 1.94e-60

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 194.15  E-value: 1.94e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHNFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ---- 76
Cdd:COG1121    1 MMMMPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRRigyv 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  77 -QRdicmvFQSYALFPhMSLGDNVGYGL----KMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARAL 151
Cdd:COG1121   81 pQR-----AEVDWDFP-ITVRDVVLMGRygrrGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARAL 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKImQLGSPQELYRQPA 229
Cdd:COG1121  155 AQDPDLLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDRVLLLNRGLV-AHGPPEEVLTPEN 230
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 8-224 2.40e-60

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 193.55  E-value: 2.40e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNT-VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSI-----QQRDIC 81
Cdd:cd03256    2 EVENLSKTYPNGKkALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGkalrqLRRQIG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSYALFPHMSLGDNVGYGL--------KMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALIL 153
Cdd:cd03256   82 MIFQQFNLIERLSVLENVLSGRlgrrstwrSLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALMQ 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 154 KPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:cd03256  162 QPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAEL 232
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 7-235 5.64e-60

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 196.18  E-value: 5.64e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ----- 77
Cdd:PRK11153   2 IELKNISKVFPQGgrtiHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKElrkar 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RDICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:PRK11153  82 RQIGMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP----ASRFM 233
Cdd:PRK11153 162 LLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHPkhplTREFI 241


                 ..
gi 757596975 234 AS 235
Cdd:PRK11153 242 QS 243
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 7-228 5.85e-59

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 191.51  E-value: 5.85e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTNT-----VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT-DRSIQQRDI 80
Cdd:TIGR04521   1 IKLKNVSYIYQPGTpfekkALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITaKKKKKLKDL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   81 C----MVFQsyalFPHMSL-----GDNVGYGLKMLGLPKAEIRKRVDEALELVDL-AGFADR--FvdQISGGQQQRVALA 148
Cdd:TIGR04521  81 RkkvgLVFQ----FPEHQLfeetvYKDIAFGPKNLGLSEEEAEERVKEALELVGLdEEYLERspF--ELSGGQMRRVAIA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:TIGR04521 155 GVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSDV 234
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 7-229 7.58e-59

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 192.58  E-value: 7.58e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKP---TEGRMFIDGEDVTD------R 73
Cdd:COG0444    2 LEVRNLKVYFPTRrgvvKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLLKlsekelR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  74 SIQQRDICMVFQ-SY-ALFPHMSLGDNVGYGLKM-LGLPKAEIRKRVDEALELVDL---AGFADRFVDQISGGQQQRVAL 147
Cdd:COG0444   82 KIRGREIQMIFQdPMtSLNPVMTVGDQIAEPLRIhGGLSKAEARERAIELLERVGLpdpERRLDRYPHELSGGMRQRVMI 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 148 ARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:COG0444  162 ARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELFEN 241


                 ..
gi 757596975 228 PA 229
Cdd:COG0444  242 PR 243
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 8-229 1.83e-58

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 188.80  E-value: 1.83e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQR---DICMVF 84
Cdd:cd03219    2 EVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIarlGIGRTF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMSLGDNV--------GYGLKMLGLPK--AEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILK 154
Cdd:cd03219   82 QIPRLFPELTVLENVmvaaqartGSGLLLARARReeREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATD 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 155 PKVLLFDEPLSNLDANLRRSMREKIRELqQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPA 229
Cdd:cd03219  162 PKLLLLDEPAAGLNPEETEELAELIREL-RERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRNNPR 235
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 7-215 1.91e-58

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 186.45  E-value: 1.91e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ-QRDICMVFQ 85
Cdd:cd03230    1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEvKRRIGYLPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYglkmlglpkaeirkrvdealelvdlagfadrfvdqiSGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:cd03230   81 EPSLYENLTVRENLKL------------------------------------SGGMKQRLALAQALLHDPELLILDEPTS 124

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 757596975 166 NLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:cd03230  125 GLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 7-219 5.24e-58

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 187.91  E-value: 5.24e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDG------EDVTDRSIQQ--R 78
Cdd:PRK11124   3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGnhfdfsKTPSDKAIRElrR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 DICMVFQSYALFPHMSLGDN-VGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:PRK11124  83 NVGMVFQQYNLWPHLTVQQNlIEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQV 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:PRK11124 163 LLFDEPTAALDPEITAQIVSIIRELAET-GITQVIVTHEVEVARKTASRVVYMENGHIVEQG 223
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
7-237 2.34e-57

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 185.99  E-value: 2.34e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGE------DVTDRSIQQ--R 78
Cdd:COG4161    3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHqfdfsqKPSEKAIRLlrQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 DICMVFQSYALFPHMSLGDN-VGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:COG4161   83 KVGMVFQQYNLWPHLTVMENlIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSpQELYRQPASRFMASFM 237
Cdd:COG4161  163 LLFDEPTAALDPEITAQVVEIIRELSQT-GITQVIVTHEVEFARKVASQVVYMEKGRIIEQGD-ASHFTQPQTEAFAHYL 240
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
8-215 3.04e-56

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 181.94  E-value: 3.04e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMVFQ 85
Cdd:COG4619    2 ELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEwrRQVAYVPQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPhMSLGDNVGYGLKMLGLPKAeiRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPL 164
Cdd:COG4619   82 EPALWG-GTVRDNLPFPFQLRERKFD--RERALELLERLGLpPDILDKPVERLSGGERQRLALIRALLLQPDVLLLDEPT 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 757596975 165 SNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:COG4619  159 SALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 8-219 8.24e-56

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 179.94  E-value: 8.24e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMVFQ 85
Cdd:cd03214    1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKElaRKIAYVPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 syalfphmslgdnvgyglkmlglpkaeirkrvdeALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:cd03214   81 ----------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTS 126

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 757596975 166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:cd03214  127 HLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 7-214 3.99e-55

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 179.37  E-value: 3.99e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTNTVI-DDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT---DRSIQQ--RDI 80
Cdd:TIGR02673   2 IEFHNVSKAYPGGVAAlHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNrlrGRQLPLlrRRI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   81 CMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:TIGR02673  82 GVVFQDFRLLPDRTVYENVALPLEVRGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLA 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 757596975  161 DEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGK 214
Cdd:TIGR02673 162 DEPTGNLDPDLSERILDLLKRLNKR-GTTVIVATHDLSLVDRVAHRVIILDDGR 214
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 7-224 1.68e-54

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 178.08  E-value: 1.68e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFG--TNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDV-TDRSIQQRDICMV 83
Cdd:cd03263    1 LQIRNLTKTYKkgTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIrTDRKAARQSLGYC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEP 163
Cdd:cd03263   81 PQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEP 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 164 LSNLDANLRRSMREKIRELQQQFNItsLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:cd03263  161 TSGLDPASRRAIWDLILEVRKGRSI--ILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQEL 219
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
7-235 7.43e-54

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 177.69  E-value: 7.43e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVtdRSIQQRD------- 79
Cdd:COG4598    9 LEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEI--RLKPDRDgelvpad 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 ----------ICMVFQSYALFPHMSLGDNVGYG-LKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALA 148
Cdd:COG4598   87 rrqlqrirtrLGMVFQSFNLWSHMTVLENVIEApVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAAIA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNiTSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:COG4598  167 RALAMEPEVMLFDEPTSALDPELVGEVLKVMRDLAEEGR-TMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGNP 245

                        250
                 ....*....|.
gi 757596975 229 AS----RFMAS 235
Cdd:COG4598  246 KSerlrQFLSS 256
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 8-217 7.74e-54

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 176.18  E-value: 7.74e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDrsiQQRDICMVFQSY 87
Cdd:cd03235    1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEK---ERKRIGYVPQRR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  88 AL---FPhMSLGDNVGYGL----KMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:cd03235   78 SIdrdFP-ISVRDVVLMGLyghkGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLL 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 161 DEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQ 217
Cdd:cd03235  157 DEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLLNRTVVAS 212
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 7-215 1.36e-53

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 175.29  E-value: 1.36e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTV-IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD---RSIQ--QRDI 80
Cdd:cd03292    1 IEFINVTKTYPNGTAaLDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDlrgRAIPylRRKI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 CMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:cd03292   81 GVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIA 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 161 DEPLSNLDANLRRsmreKIRELQQQFN---ITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:cd03292  161 DEPTGNLDPDTTW----EIMNLLKKINkagTTVVVATHAKELVDTTRHRVIALERGKL 214
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 22-165 1.51e-53

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 173.22  E-value: 1.51e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMVFQSYALFPHMSLGDNV 99
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSlrKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  100 GYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVD----QISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRPVGerpgTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 7-225 2.15e-53

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 175.95  E-value: 2.15e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTNT-VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD---RSIQQ--RDI 80
Cdd:TIGR02315   2 LEVENLSKVYPNGKqALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKlrgKKLRKlrRRI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   81 CMVFQSYALFPHMSLGDNVGYGL--------KMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALI 152
Cdd:TIGR02315  82 GMIFQHYNLIERLTVLENVLHGRlgykptwrSLLGRFSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIARALA 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975  153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELY 225
Cdd:TIGR02315 162 QQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSELD 234
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 11-286 5.27e-53

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 178.38  E-value: 5.27e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   11 NVTKRFGTNTVidDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDR------SIQQRDICMVF 84
Cdd:TIGR02142   4 RFSKRLGDFSL--DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSrkgiflPPEKRRIGYVF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   85 QSYALFPHMSLGDNVGYGLKMLGLPKAEIRKrvDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPL 164
Cdd:TIGR02142  82 QEARLFPHLSVRGNLRYGMKRARPSERRISF--ERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  165 SNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFM----ASFMGDA 240
Cdd:TIGR02142 160 AALDDPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPWLaredQGSLIEG 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 757596975  241 NIFPAT----LTHDSVNifNYHLPRPAQLATDNTEITVGVRPEAITLSLQ 286
Cdd:TIGR02142 240 VVAEHDqhygLTALRLG--GGHLWVPENLGPTGARLRLRVPARDVSLALQ 287
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 22-219 9.39e-53

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 173.81  E-value: 9.39e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT----DRSIqqrdicmVFQSYALFPHMSLGD 97
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITepgpDRMV-------VFQNYSLLPWLTVRE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   98 NVGYGLK--MLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSM 175
Cdd:TIGR01184  74 NIALAVDrvLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNL 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 757596975  176 REKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:TIGR01184 154 QEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIG 197
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 7-235 1.08e-52

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 174.99  E-value: 1.08e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTN---------TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT--DRSI 75
Cdd:TIGR02769   3 LEVRDVTHTYRTGglfgakqraPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYqlDRKQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   76 Q---QRDICMVFQ-SYALF-PHMSLGDNVGYGLK-MLGLPKAEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALA 148
Cdd:TIGR02769  83 RrafRRDVQLVFQdSPSAVnPRMTVRQIIGEPLRhLTSLDESEQKARIAELLDMVGLrSEDADKLPRQLSGGQLQRINIA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL--YR 226
Cdd:TIGR02769 163 RALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQLlsFK 242


                  ....*....
gi 757596975  227 QPASRFMAS 235
Cdd:TIGR02769 243 HPAGRNLQS 251
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 7-219 2.12e-52

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 172.08  E-value: 2.12e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSiqQRDICMVFQS 86
Cdd:cd03269    1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAA--RNRIGYLPEE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:cd03269   79 RGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSG 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 757596975 167 LDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:cd03269  159 LDPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
12-242 2.15e-52

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 177.92  E-value: 2.15e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  12 VTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD------RSIQQRDICMVFQ 85
Cdd:PRK10070  34 ILEKTGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKisdaelREVRRKKIAMVFQ 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:PRK10070 114 SFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFS 193

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGDANI 242
Cdd:PRK10070 194 ALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDI 270
cbiO PRK13650
energy-coupling factor transporter ATPase;
5-225 3.82e-52

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 173.76  E-value: 3.82e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   5 NFVELKNVTKRFGTNT---VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSI--QQRD 79
Cdd:PRK13650   3 NIIEVKNLTFKYKEDQekyTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVwdIRHK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 ICMVFQSY-ALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVL 158
Cdd:PRK13650  83 IGMVFQNPdNQFVGATVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKII 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 159 LFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAfAVSDMVLVMNKGKIMQLGSPQELY 225
Cdd:PRK13650 163 ILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPRELF 228
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 8-214 4.11e-52

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 169.73  E-value: 4.11e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDicmvfqsy 87
Cdd:cd00267    1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELR-------- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  88 alfphmslgDNVGYglkmlglpkaeirkrvdealelvdlagfadrfVDQISGGQQQRVALARALILKPKVLLFDEPLSNL 167
Cdd:cd00267   73 ---------RRIGY--------------------------------VPQLSGGQRQRVALARALLLNPDLLLLDEPTSGL 111

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 757596975 168 DANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGK 214
Cdd:cd00267  112 DPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 7-224 1.69e-51

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 181.57  E-value: 1.69e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT--VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICM 82
Cdd:COG2274  474 IELENVSFRYPGDSppVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASlrRQIGV 553

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFpHMSLGDNVgyglkMLGLPKAEIrKRVDEALELVDLAGFADRFVD-----------QISGGQQQRVALARAL 151
Cdd:COG2274  554 VLQDVFLF-SGTIRENI-----TLGDPDATD-EEIIEAARLAGLHDFIEALPMgydtvvgeggsNLSGGQRQRLAIARAL 626

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSeAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:COG2274  627 LRNPRILILDEATSALDAETEAIILENLRRLLK--GRTVIIIAHRLS-TIRLADRIIVLDKGRIVEDGTHEEL 696
3a0107s01c2 TIGR00972
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ...
 7-231 2.68e-51

phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]


Pssm-ID: 273372 [Multi-domain]  Cd Length: 247  Bit Score: 170.55  E-value: 2.68e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLR-------LVAGLEkpTEGRMFIDGEDVTDRSIQ--- 76
Cdd:TIGR00972   2 IEIENLNLFYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRslnrmndLVPGVR--IEGKVLFDGQDIYDKKIDvve 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   77 -QRDICMVFQSYALFPhMSLGDNVGYGLKMLGL-PKAEIRKRVDEALELVDL-AGFADRFVDQ---ISGGQQQRVALARA 150
Cdd:TIGR00972  80 lRRRVGMVFQKPNPFP-MSIYDNIAYGPRLHGIkDKKELDEIVEESLKKAALwDEVKDRLHDSalgLSGGQQQRLCIARA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  151 LILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNItsLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPAS 230
Cdd:TIGR00972 159 LAVEPEVLLLDEPTSALDPIATGKIEELIQELKKKYTI--VIVTHNMQQAARISDRTAFFYDGELVEYGPTEQIFTNPKE 236


                  .
gi 757596975  231 R 231
Cdd:TIGR00972 237 K 237
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 7-219 4.21e-51

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 168.83  E-value: 4.21e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVidDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQS 86
Cdd:cd03298    1 VRLDKIRFSYGEQPM--HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADRPVSMLFQE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:cd03298   79 NNLFAHLTVEQNVGLGLSPGLKLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAA 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 757596975 167 LDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:cd03298  159 LDPALRAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 7-217 8.34e-51

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 168.77  E-value: 8.34e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQR---- 78
Cdd:COG4181    9 IELRGLTKTVGTGagelTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARarlr 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 --DICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAeiRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPK 156
Cdd:COG4181   89 arHVGFVFQSFQLLPTLTALENVMLPLELAGRRDA--RARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEPA 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 157 VLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAfAVSDMVLVMNKGKIMQ 217
Cdd:COG4181  167 ILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALA-ARCDRVLRLRAGRLVE 226
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 7-228 1.05e-50

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 169.45  E-value: 1.05e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLR-------LVAGLEkpTEGRMFIDGEDVTDRSIQQ-- 77
Cdd:COG1117   12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRclnrmndLIPGAR--VEGEILLDGEDIYDPDVDVve 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 --RDICMVFQSYALFPhMSLGDNVGYGLKMLGL-PKAEIRKRVDEALELVDL----------AGFAdrfvdqISGGQQQR 144
Cdd:COG1117   90 lrRRVGMVFQKPNPFP-KSIYDNVAYGLRLHGIkSKSELDEIVEESLRKAALwdevkdrlkkSALG------LSGGQQQR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 145 VALARALILKPKVLLFDEPLSNLD--ANLRrsMREKIRELQQQFNItsLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQ 222
Cdd:COG1117  163 LCIARALAVEPEVLLMDEPTSALDpiSTAK--IEELILELKKDYTI--VIVTHNMQQAARVSDYTAFFYLGELVEFGPTE 238


                 ....*.
gi 757596975 223 ELYRQP 228
Cdd:COG1117  239 QIFTNP 244
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
10-247 1.48e-50

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 169.48  E-value: 1.48e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  10 KNVTKRFGT---------NTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT--DRSIQ-- 76
Cdd:PRK10419   7 SGLSHHYAHgglsgkhqhQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAklNRAQRka 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  77 -QRDICMVFQSY--ALFPHMSLGDNVGYGLK-MLGLPKAEIRKRVDEALELVDLA-GFADRFVDQISGGQQQRVALARAL 151
Cdd:PRK10419  87 fRRDIQMVFQDSisAVNPRKTVREIIREPLRhLLSLDKAERLARASEMLRAVDLDdSVLDKRPPQLSGGQLQRVCLARAL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQS--EAFAvsDMVLVMNKGKIM--QLGSPQELYRQ 227
Cdd:PRK10419 167 AVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRlvERFC--QRVMVMDNGQIVetQPVGDKLTFSS 244

                        250       260
                 ....*....|....*....|
gi 757596975 228 PASRFMASFMGDAniFPATL 247
Cdd:PRK10419 245 PAGRVLQNAVLPA--FPVRR 262
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
8-217 1.62e-50

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 168.72  E-value: 1.62e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQrdiCMVFQSY 87
Cdd:PRK11248   3 QISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER---GVVFQNE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  88 ALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNL 167
Cdd:PRK11248  80 GLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGAL 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 757596975 168 DANLRRSMREKIRELQQQFNITSLYVTHDQSEA-FAVSDMVLVM-NKGKIMQ 217
Cdd:PRK11248 160 DAFTREQMQTLLLKLWQETGKQVLLITHDIEEAvFMATELVLLSpGPGRVVE 211
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 14-228 1.95e-50

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 175.64  E-value: 1.95e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  14 KRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTT----VLRLVaglekPTEGRMFIDGEDVTDRSIQQ-----RDICMVF 84
Cdd:COG4172  294 RTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTlglaLLRLI-----PSEGEIRFDGQDLDGLSRRAlrplrRRMQVVF 368

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QS-YA-LFPHMSLGDNVGYGLKML--GLPKAEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARALILKPKVLL 159
Cdd:COG4172  369 QDpFGsLSPRMTVGQIIAEGLRVHgpGLSAAERRARVAEALEEVGLdPAARHRYPHEFSGGQRQRIAIARALILEPKLLV 448

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 160 FDEPLSNLDanlrRSMREKI----RELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:COG4172  449 LDEPTSALD----VSVQAQIldllRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAP 517
cbiO PRK13637
energy-coupling factor transporter ATPase;
22-227 1.97e-50

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 169.84  E-value: 1.97e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDI----CMVFQ--SYALFPHMSL 95
Cdd:PRK13637  23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVKLSDIrkkvGLVFQypEYQLFEETIE 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  96 GDnVGYGLKMLGLPKAEIRKRVDEALELV--DLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRR 173
Cdd:PRK13637 103 KD-IAFGPINLGLSEEEIENRVKRAMNIVglDYEDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRD 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 757596975 174 SMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:PRK13637 182 EILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFKE 235
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 7-203 3.05e-50

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 166.50  E-value: 3.05e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ-QRDICMVFQ 85
Cdd:COG4133    3 LEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDyRRRLAYLGH 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRkrVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:COG4133   83 ADGLKPELTVRENLRFWAALYGLRADREA--IDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFT 160

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 757596975 166 NLDANLRRSMREKIRELQQQFNITsLYVTHDQSEAFAV 203
Cdd:COG4133  161 ALDAAGVALLAELIAAHLARGGAV-LLTTHQPLELAAA 197
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 7-239 7.29e-50

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 166.85  E-value: 7.29e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFI-DGEDVTDRSI--QQRDI--- 80
Cdd:PRK11264   4 IEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVgDITIDTARSLsqQKGLIrql 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 ----CMVFQSYALFPHMSLGDNVGYG-LKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKP 155
Cdd:PRK11264  84 rqhvGFVFQNFNLFPHRTVLENIIEGpVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRP 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 156 KVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELY---RQPASR- 231
Cdd:PRK11264 164 EVILFDEPTSALDPELVGEVLNTIRQLAQE-KRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFadpQQPRTRq 242


                 ....*...
gi 757596975 232 FMASFMGD 239
Cdd:PRK11264 243 FLEKFLLQ 250
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 7-215 1.37e-49

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 165.08  E-value: 1.37e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQS 86
Cdd:cd03268    1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEALRRIGALIEA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLGLPKaeirKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:cd03268   81 PGFYPNLTARENLRLLARLLGIRK----KRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNG 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 757596975 167 LDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:cd03268  157 LDPDGIKELRELILSLRDQ-GITVLISSHLLSEIQKVADRIGIINKGKL 204
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 7-231 1.34e-48

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 163.10  E-value: 1.34e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQR---DICMV 83
Cdd:cd03218    1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRarlGIGYL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEP 163
Cdd:cd03218   81 PQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEP 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 164 LSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASR 231
Cdd:cd03218  161 FAGVDPIAVQDIQKIIKILKDR-GIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANELVR 227
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 7-227 1.60e-48

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 164.90  E-value: 1.60e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ-------Rd 79
Cdd:COG4152    2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPEDRRRigylpeeR- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 icmvfqsyALFPHMSLGDNVGY--GLKmlGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:COG4152   81 --------GLYPKMKVGEQLVYlaRLK--GLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPEL 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 158 LLFDEPLSNLD---ANLrrsMREKIRELQQQfNITSLYVTH--DQSEAFAvsDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:COG4152  151 LILDEPFSGLDpvnVEL---LKDVIRELAAK-GTTVIFSSHqmELVEELC--DRIVIINKGRKVLSGSVDEIRRQ 219
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
3-227 1.83e-48

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 164.42  E-value: 1.83e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   3 QHNFVELKNVTKRFGTNT--VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--R 78
Cdd:PRK13635   2 KEEIIRVEHISFRYPDAAtyALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWDvrR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 DICMVFQSY-ALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:PRK13635  82 QVGMVFQNPdNQFVGATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDI 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAfAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:PRK13635 162 IILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEA-AQADRVIVMNKGEILEEGTPEEIFKS 230
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 7-219 1.19e-47

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 160.23  E-value: 1.19e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT----VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ-QRDIC 81
Cdd:cd03266    2 ITADALTKRFRDVKktvqAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAEaRRRLG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFD 161
Cdd:cd03266   82 FVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLD 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 162 EPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:cd03266  162 EPTTGLDVMATRALREFIRQLRAL-GKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 8-224 2.48e-47

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 159.52  E-value: 2.48e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQR---DICMVF 84
Cdd:cd03224    2 EVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERaraGIGYVP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMSLGDNvgygLKM--LGLPKAEIRKRVDEALELV-DLAGFADRFVDQISGGQQQRVALARALILKPKVLLFD 161
Cdd:cd03224   82 EGRRIFPELTVEEN----LLLgaYARRRAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLD 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 162 EPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:cd03224  158 EPSEGLAPKIVEEIFEAIRELRDE-GVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAEL 219
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 7-219 3.54e-47

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 158.90  E-value: 3.54e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGsMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRD-ICMVFQ 85
Cdd:cd03264    1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRrIGYLPQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:cd03264   80 EFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTA 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 757596975 166 NLDANLRRSMREKIRELQQqfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:cd03264  160 GLDPEERIRFRNLLSELGE--DRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
9-215 1.90e-46

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 157.19  E-value: 1.90e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   9 LKNVTKRFGTNT----VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRD----- 79
Cdd:NF038007   4 MQNAEKCYITKTiktkVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVTNLSYSQKIilrre 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 -ICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVL 158
Cdd:NF038007  84 lIGYIFQSFNLIPHLSIFDNVALPLKYRGVAKKERIERVNQVLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPALL 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 159 LFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQsEAFAVSDMVLVMNKGKI 215
Cdd:NF038007 164 LADEPTGNLDSKNARAVLQQLKYINQK-GTTIIMVTHSD-EASTYGNRIINMKDGKL 218
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
7-227 2.20e-46

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 165.72  E-value: 2.20e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT-VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMV 83
Cdd:COG1132  340 IEFENVSFSYPGDRpVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESlrRQIGVV 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSYALFpHMSLGDNVGYglkmlGLPKAEiRKRVDEALELVDLAGFADRFVD-----------QISGGQQQRVALARALI 152
Cdd:COG1132  420 PQDTFLF-SGTIRENIRY-----GRPDAT-DEEVEEAAKAAQAHEFIEALPDgydtvvgergvNLSGGQRQRIAIARALL 492

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQS---EAfavsDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:COG1132  493 KDPPILILDEATSALDTETEALIQEALERLMK--GRTTIVIAHRLStirNA----DRILVLDDGRIVEQGTHEELLAR 564
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
26-230 4.60e-46

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 156.67  E-value: 4.60e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  26 SLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQSYALFPHMSLGDNVGYGLKM 105
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNP 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 106 lGLP-KAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQ 184
Cdd:PRK10771  99 -GLKlNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQVCQ 177

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 757596975 185 QFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPAS 230
Cdd:PRK10771 178 ERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELLSGKAS 223
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 7-214 5.76e-46

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 154.08  E-value: 5.76e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT--VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD---RSIQQRdIC 81
Cdd:cd03228    1 IEFKNVSFSYPGRPkpVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDldlESLRKN-IA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSYALFpHMSLGDNVgyglkmlglpkaeirkrvdealelvdlagfadrfvdqISGGQQQRVALARALILKPKVLLFD 161
Cdd:cd03228   80 YVPQDPFLF-SGTIRENI-------------------------------------LSGGQRQRIAIARALLRDPPILILD 121

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 757596975 162 EPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSEAfAVSDMVLVMNKGK 214
Cdd:cd03228  122 EATSALDPETEALILEALRALAK--GKTVIVIAHRLSTI-RDADRIIVLDDGR 171
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 26-219 9.87e-46

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 155.02  E-value: 9.87e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   26 SLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQSYALFPHMSLGDNVGYGLKM 105
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLAPYQRPVSMLFQENNLFAHLTVRQNIGLGLHP 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  106 LGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQ 185
Cdd:TIGR01277  98 GLKLNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQLCSE 177

                         170       180       190
                  ....*....|....*....|....*....|....
gi 757596975  186 FNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:TIGR01277 178 RQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 7-227 1.26e-45

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 163.39  E-value: 1.26e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF-GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QRDICMV 83
Cdd:COG4988  337 IELEDVSFSYpGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPAswRRQIAWV 416

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSYALFpHMSLGDNVgyglkMLGLPKAEiRKRVDEALELVDLAGFADRFVDQI-----------SGGQQQRVALARALI 152
Cdd:COG4988  417 PQNPYLF-AGTIRENL-----RLGRPDAS-DEELEAALEAAGLDEFVAALPDGLdtplgeggrglSGGQAQRLALARALL 489

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSEAfAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:COG4988  490 RDAPLLLLDEPTAHLDAETEAEILQALRRLAK--GRTVILITHRLALL-AQADRILVLDDGRIVEQGTHEELLAK 561
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 9-197 1.54e-45

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 154.31  E-value: 1.54e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    9 LKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD------RSIQQRDICM 82
Cdd:TIGR03608   1 LKNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPlnskkaSKFRREKLGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   83 VFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDE 162
Cdd:TIGR03608  81 LFQNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADE 160

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 757596975  163 PLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQ 197
Cdd:TIGR03608 161 PTGSLDPKNRDEVLDLLLELNDE-GKTIIIVTHDP 194
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 7-224 9.23e-45

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 154.38  E-value: 9.23e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGT--NTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICM 82
Cdd:PRK13632   8 IKVENVSFSYPNseNNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKEirKKIGI 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSY-ALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFD 161
Cdd:PRK13632  88 IFQNPdNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFD 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 162 EPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFaVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:PRK13632 168 ESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKLIAQGKPKEI 229
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 7-228 9.82e-45

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 153.84  E-value: 9.82e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGL-----EKPTEGRMFIDGEDVTDRSIQ----Q 77
Cdd:PRK14267   5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLlelneEARVEGEVRLFGRNIYSPDVDpievR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RDICMVFQSYALFPHMSLGDNVGYGLKMLGL--PKAEIRKRVDEALELVDL-AGFADRFVD---QISGGQQQRVALARAL 151
Cdd:PRK14267  85 REVGMVFQYPNPFPHLTIYDNVAIGVKLNGLvkSKKELDERVEWALKKAALwDEVKDRLNDypsNLSGGQRQRLVIARAL 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNItsLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK14267 165 AMKPKILLMDEPTANIDPVGTAKIEELLFELKKEYTI--VLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENP 239
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 1-225 3.32e-44

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 152.98  E-value: 3.32e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHNFVELKNVTKRFGTNT--VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ-- 76
Cdd:PRK13648   2 EDKNSIIVFKNVSFQYQSDAsfTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEkl 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  77 QRDICMVFQS-YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKP 155
Cdd:PRK13648  82 RKHIGIVFQNpDNQFVGSIVKYDVAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNP 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 156 KVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAfAVSDMVLVMNKGKIMQLGSPQELY 225
Cdd:PRK13648 162 SVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEA-MEADHVIVMNKGTVYKEGTPTEIF 230
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 7-229 4.63e-44

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 159.16  E-value: 4.63e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF--GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICM 82
Cdd:COG4987  334 LELEDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDlrRRIAV 413

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFpHMSLGDNVgyglkMLGLPKA---EIRkrvdEALELVDLAGFADRFVD-----------QISGGQQQRVALA 148
Cdd:COG4987  414 VPQRPHLF-DTTLRENL-----RLARPDAtdeELW----AALERVGLGDWLAALPDgldtwlgeggrRLSGGERRRLALA 483

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSEAFAVsDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:COG4987  484 RALLRDAPILLLDEPTEGLDAATEQALLADLLEALA--GRTVLLITHRLAGLERM-DRILVLEDGRIVEQGTHEELLAQN 560


                 .
gi 757596975 229 A 229
Cdd:COG4987  561 G 561
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
1-231 1.39e-43

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 151.46  E-value: 1.39e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHNFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--- 77
Cdd:PRK11831   2 QSVANLVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRlyt 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 --RDICMVFQSYALFPHMSLGDNVGYGLK-MLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILK 154
Cdd:PRK11831  82 vrKRMSMLFQSGALFTDMNVFDNVAYPLReHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALE 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 155 PKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASR 231
Cdd:PRK11831 162 PDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANPDPR 238
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 7-224 1.97e-43

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 150.23  E-value: 1.97e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMVF 84
Cdd:COG4604    2 IEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRElaKRLAILR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMSLGDNVGYGL----KmlGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:COG4604   82 QENHINSRLTVRELVAFGRfpysK--GRLTAEDREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVLL 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757596975 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:COG4604  160 DEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEI 223
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 8-231 2.50e-43

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 149.79  E-value: 2.50e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQR---DIcmvf 84
Cdd:COG1137    5 EAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHKRarlGI---- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 qSY-----ALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLL 159
Cdd:COG1137   81 -GYlpqeaSIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFIL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 160 FDEPLSNLD----ANLRRSmrekIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASR 231
Cdd:COG1137  160 LDEPFAGVDpiavADIQKI----IRHLKER-GIGVLITDHNVRETLGICDRAYIISEGKVLAEGTPEEILNNPLVR 230
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 8-229 2.63e-43

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 149.36  E-value: 2.63e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQR---DICMVF 84
Cdd:COG0410    5 EVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIarlGIGYVP 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMSLGDNvgygLKM---LGLPKAEIRKRVDEALELV-DLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:COG0410   85 EGRRIFPSLTVEEN----LLLgayARRDRAEVRADLERVYELFpRLKERRRQRAGTLSGGEQQMLAIGRALMSRPKLLLL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975 161 DEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPA 229
Cdd:COG0410  161 DEPSLGLAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELLADPE 228
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
3-240 6.00e-43

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 149.35  E-value: 6.00e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   3 QHNFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDV-----TDRSIQQ 77
Cdd:PRK10619   2 SENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTInlvrdKDGQLKV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RD----------ICMVFQSYALFPHMSLGDNVGYG-LKMLGLPKAEIRKRVDEALELVDLAGFA-DRFVDQISGGQQQRV 145
Cdd:PRK10619  82 ADknqlrllrtrLTMVFQHFNLWSHMTVLENVMEApIQVLGLSKQEARERAVKYLAKVGIDERAqGKYPVHLSGGQQQRV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 146 ALARALILKPKVLLFDEPLSNLDANLrrsMREKIRELQQ--QFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQE 223
Cdd:PRK10619 162 SIARALAMEPEVLLFDEPTSALDPEL---VGEVLRIMQQlaEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQ 238

                        250
                 ....*....|....*..
gi 757596975 224 LYRQPASRFMASFMGDA 240
Cdd:PRK10619 239 LFGNPQSPRLQQFLKGS 255
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 22-228 7.53e-43

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 150.89  E-value: 7.53e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT--DRSIQQ---RDICMVFQS-YA-LFPHMS 94
Cdd:PRK11308  31 LDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLkaDPEAQKllrQKIQIVFQNpYGsLNPRKK 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  95 LGDNVGYGLKM-LGLPKAEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLR 172
Cdd:PRK11308 111 VGQILEEPLLInTSLSAAERREKALAMMAKVGLrPEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQ 190

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 173 RSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK11308 191 AQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNNP 246
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 5-228 8.24e-43

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 148.91  E-value: 8.24e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   5 NFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGL-----EKPTEGRMFIDGEDV--TDRSIQQ 77
Cdd:PRK14247   2 NKIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDIfkMDVIELR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RDICMVFQSYALFPHMSLGDNVGYGLKM--LGLPKAEIRKRVDEALELVDL-AGFADRF---VDQISGGQQQRVALARAL 151
Cdd:PRK14247  82 RRVQMVFQIPNPIPNLSIFENVALGLKLnrLVKSKKELQERVRWALEKAQLwDEVKDRLdapAGKLSGGQQQRLCIARAL 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNItsLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK14247 162 AFQPEVLLADEPTANLDPENTAKIESLFLELKKDMTI--VLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNP 236
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
8-228 9.35e-43

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 148.83  E-value: 9.35e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNT---------VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQR 78
Cdd:COG4167    6 EVRNLSKTFKYRTglfrrqqfeAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLEYGDYKYR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 --DICMVFQ--SYALFPHMSLGdnvgyglKMLGLP--------KAEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRV 145
Cdd:COG4167   86 ckHIRMIFQdpNTSLNPRLNIG-------QILEEPlrlntdltAEEREERIFATLRLVGLlPEHANFYPHMLSSGQKQRV 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 146 ALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELY 225
Cdd:COG4167  159 ALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEVF 238


                 ...
gi 757596975 226 RQP 228
Cdd:COG4167  239 ANP 241
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
6-210 1.02e-42

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 154.41  E-value: 1.02e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   6 FVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSI---QQRDICM 82
Cdd:COG1129    4 LLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPrdaQAAGIAI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFPHMSLGDNV--GYGLKMLGL-PKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLL 159
Cdd:COG1129   84 IHQELNLVPNLSVAENIflGREPRRGGLiDWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRDARVLI 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 757596975 160 FDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVM 210
Cdd:COG1129  164 LDEPTASLTEREVERLFRIIRRLKAQ-GVAIIYISHRLDEVFEIADRVTVL 213
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
5-227 1.23e-42

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 149.08  E-value: 1.23e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   5 NFVELKNVTKRFGTN------TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRS---- 74
Cdd:PRK13633   3 EMIKCKNVSYKYESNeestekLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEEnlwd 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  75 IQQRdICMVFQSyalfPHMSL-----GDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALAR 149
Cdd:PRK13633  83 IRNK-AGMVFQN----PDNQIvativEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAG 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 150 ALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAfAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:PRK13633 158 ILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEA-VEADRIIVMDSGKVVMEGTPKEIFKE 234
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 7-215 2.07e-42

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 144.88  E-value: 2.07e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSiqqrdicmvfqs 86
Cdd:cd03216    1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFAS------------ 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 yalfphmslgdnvgyglkmlglPKAEIRKRVdealelvdlagfadRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:cd03216   69 ----------------------PRDARRAGI--------------AMVYQLSVGERQMVEIARALARNARLLILDEPTAA 112

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 757596975 167 LDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:cd03216  113 LTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRV 160
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
8-223 1.05e-41

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 146.03  E-value: 1.05e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICM-VF-Q 85
Cdd:COG4559    3 EAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELARRRaVLpQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYAL-FPhMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALI-------LKPKV 157
Cdd:COG4559   83 HSSLaFP-FTVEEVVALGRAPHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAqlwepvdGGPRW 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 158 LLFDEPLSNLD-ANLRRSMReKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQE 223
Cdd:COG4559  162 LFLDEPTSALDlAHQHAVLR-LARQLARR-GGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEE 226
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 8-215 1.61e-41

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 143.94  E-value: 1.61e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNT-VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSiQQRDICMVFQS 86
Cdd:cd03226    1 RIENISFSYKKGTeILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKE-RRKSIGYVMQD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 --YALFPHmSLGDNVGYGLKMLGLPKAEIRkrvdEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPL 164
Cdd:cd03226   80 vdYQLFTD-SVREELLLGLKELDAGNEQAE----TVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPT 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 757596975 165 SNLDanlRRSMR---EKIRELQQQFNiTSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:cd03226  155 SGLD---YKNMErvgELIRELAAQGK-AVIVITHDYEFLAKVCDRVLLLANGAI 204
cbiO PRK13642
energy-coupling factor transporter ATPase;
4-225 1.69e-41

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 146.01  E-value: 1.69e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   4 HNFVELKNVTKRFGTNTVIDDL---SLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QR 78
Cdd:PRK13642   2 NKILEVENLVFKYEKESDVNQLngvSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWnlRR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 DICMVFQSY-ALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:PRK13642  82 KIGMVFQNPdNQFVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEI 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAfAVSDMVLVMNKGKIMQLGSPQELY 225
Cdd:PRK13642 162 IILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEA-ASSDRILVMKAGEIIKEAAPSELF 228
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 8-223 1.74e-41

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 145.30  E-value: 1.74e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDicmvfQSY 87
Cdd:PRK13548   4 EARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELA-----RRR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  88 ALFP-HMSLG------DNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALI------LK 154
Cdd:PRK13548  79 AVLPqHSSLSfpftveEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdGP 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 155 PKVLLFDEPLSNLDanLR---RSMReKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQE 223
Cdd:PRK13548 159 PRWLLLDEPTSALD--LAhqhHVLR-LARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAE 227
cbiO PRK13640
energy-coupling factor transporter ATPase;
5-228 2.05e-41

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 146.10  E-value: 2.05e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   5 NFVELKNVTKRF--GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKP---TEGRMFIDGEDVTDRSIQQ-R 78
Cdd:PRK13640   4 NIVEFKHVSFTYpdSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPddnPNSKITVDGITLTAKTVWDiR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 D-ICMVFQSY-ALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPK 156
Cdd:PRK13640  84 EkVGIVFQNPdNQFVGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPK 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 157 VLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAfAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK13640 164 IIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEIFSKV 234
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 22-228 6.53e-41

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 146.00  E-value: 6.53e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQR-----DICMVFQS--YALFPHMS 94
Cdd:PRK15079  37 VDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWravrsDIQMIFQDplASLNPRMT 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  95 LGDNVGYGLKML--GLPKAEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANL 171
Cdd:PRK15079 117 IGEIIAEPLRTYhpKLSRQEVKDRVKAMMLKVGLlPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSI 196

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 172 RRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK15079 197 QAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNP 253
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 7-227 9.51e-41

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 142.75  E-value: 9.51e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFG--TNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICM 82
Cdd:cd03251    1 VEFKNVTFRYPgdGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASlrRQIGL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFpHMSLGDNVGYglkmlGLPKAEiRKRVDEALELVDLAGFADRFVD-----------QISGGQQQRVALARAL 151
Cdd:cd03251   81 VSQDVFLF-NDTVAENIAY-----GRPGAT-REEVEEAARAANAHEFIMELPEgydtvigergvKLSGGQRQRIAIARAL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSeAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:cd03251  154 LKDPPILILDEATSALDTESERLVQAALERLMK--NRTTFVIAHRLS-TIENADRIVVLEDGKIVERGTHEELLAQ 226
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 6-224 1.33e-40

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 142.92  E-value: 1.33e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   6 FVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEG-RMFI-----DGEDVTDrsIQQRd 79
Cdd:COG1119    3 LLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLfgerrGGEDVWE--LRKR- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 ICMVfqSYALF----PHMSLGDNVGYGL-KMLGL---PKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARAL 151
Cdd:COG1119   80 IGLV--SPALQlrfpRDETVLDVVLSGFfDSIGLyrePTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARAL 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:COG1119  158 VKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEV 230
LolD_lipo_ex TIGR02211
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...
 10-215 2.82e-40

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 131266 [Multi-domain]  Cd Length: 221  Bit Score: 141.33  E-value: 2.82e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   10 KNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDV-----TDRS-IQQRD 79
Cdd:TIGR02211   5 ENLGKRYQEGkldtRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVLFNGQSLsklssNERAkLRNKK 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   80 ICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLL 159
Cdd:TIGR02211  85 LGFIYQFHHLLPDFTALENVAMPLLIGKKSVKEAKERAYEMLEKVGLEHRINHRPSELSGGERQRVAIARALVNQPSLVL 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975  160 FDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAfAVSDMVLVMNKGKI 215
Cdd:TIGR02211 165 ADEPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLELA-KKLDRVLEMKDGQL 219
heterocyst_DevA TIGR02982
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ...
 7-215 4.31e-40

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.


Pssm-ID: 274374 [Multi-domain]  Cd Length: 220  Bit Score: 140.54  E-value: 4.31e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTNT----VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDV---TDRSIQQ-- 77
Cdd:TIGR02982   2 ISIRNLNHYYGHGSlrkqVLFDINLEINPGEIVILTGPSGSGKTTLLTLIGGLRSVQEGSLKVLGQELhgaSKKQLVQlr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   78 RDICMVFQSYALFPHMSLGDNVGYGLKML-GLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPK 156
Cdd:TIGR02982  82 RRIGYIFQAHNLLGFLTARQNVQMALELQpNLSYQEARERARAMLEAVGLGDHLNYYPHNLSGGQKQRVAIARALVHHPK 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975  157 VLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDqSEAFAVSDMVLVMNKGKI 215
Cdd:TIGR02982 162 LVLADEPTAALDSKSGRDVVELMQKLAKEQGCTILMVTHD-NRILDVADRILQMEDGKL 219
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 7-224 4.43e-40

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 141.21  E-value: 4.43e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTkrFGTNT---VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVtdRSIQQ----RD 79
Cdd:cd03253    1 IEFENVT--FAYDPgrpVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDI--REVTLdslrRA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 ICMVFQSYALFpHMSLGDNVGYGlkMLGLPKAEIRkrvdEALELVDLAGFADRFVDQ-----------ISGGQQQRVALA 148
Cdd:cd03253   77 IGVVPQDTVLF-NDTIGYNIRYG--RPDATDEEVI----EAAKAAQIHDKIMRFPDGydtivgerglkLSGGEKQRVAIA 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSEAfAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:cd03253  150 RAILKNPPILLLDEATSALDTHTEREIQAALRDVSK--GRTTIVIAHRLSTI-VNADKIIVLKDGRIVERGTHEEL 222
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 1-229 8.82e-40

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 147.14  E-value: 8.82e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHNFVELKNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKT----TVLRLVAGLEKPTEGRMFIDGEDVTD 72
Cdd:COG4172    1 MMSMPLLSVEDLSVAFGQGggtvEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  73 ------RSIQQRDICMVFQ--SYALFPHMSLGDNVGYGLKM-LGLPKAEIRKRVDEALELV---DLAGFADRFVDQISGG 140
Cdd:COG4172   81 lserelRRIRGNRIAMIFQepMTSLNPLHTIGKQIAEVLRLhRGLSGAAARARALELLERVgipDPERRLDAYPHQLSGG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 141 QQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDqseaFAV----SDMVLVMNKGKIM 216
Cdd:COG4172  161 QRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHD----LGVvrrfADRVAVMRQGEIV 236

                        250
                 ....*....|...
gi 757596975 217 QLGSPQELYRQPA 229
Cdd:COG4172  237 EQGPTAELFAAPQ 249
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 7-214 8.84e-39

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 144.01  E-value: 8.84e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSiqQRD-----IC 81
Cdd:COG3845    6 LELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRS--PRDaialgIG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSYALFPHMSLGDNVGYGL---KMLGLPKAEIRKRVDEALEL----VDLagfaDRFVDQISGGQQQRVALARALILK 154
Cdd:COG3845   84 MVHQHFMLVPNLTVAENIVLGLeptKGGRLDRKAARARIRELSERygldVDP----DAKVEDLSVGEQQRVEILKALYRG 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 155 PKVLLFDEPLSNLD--------ANLRRsMREKirelqqqfNITSLYVTHDQSEAFAVSDMVLVMNKGK 214
Cdd:COG3845  160 ARILILDEPTAVLTpqeadelfEILRR-LAAE--------GKSIIFITHKLREVMAIADRVTVLRRGK 218
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
7-223 1.38e-38

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 137.84  E-value: 1.38e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQrdicmVFQS 86
Cdd:PRK11231   3 LRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQ-----LARR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFP--HM-----SLGDNVGYG----LKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKP 155
Cdd:PRK11231  78 LALLPqhHLtpegiTVRELVAYGrspwLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDT 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 156 KVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQE 223
Cdd:PRK11231 158 PVVLLDEPTTYLDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEE 224
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 7-229 1.89e-38

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 138.23  E-value: 1.89e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT-----VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIdGEDVTDRSIQQRD-- 79
Cdd:PRK13634   3 ITFQKVEHRYQYKTpferrALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTI-GERVITAGKKNKKlk 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 -----ICMVFQ--SYALFPHMSLGDnVGYGLKMLGLPKAEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARAL 151
Cdd:PRK13634  82 plrkkVGIVFQfpEHQLFEETVEKD-ICFGPMNFGVSEEDAKQKAREMIELVGLpEELLARSPFELSGGQMRRVAIAGVL 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPA 229
Cdd:PRK13634 161 AMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPD 238
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
7-224 3.49e-38

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 138.01  E-value: 3.49e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRD-ICMVFQ 85
Cdd:PRK13537   8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQrVGVVPQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:PRK13537  88 FDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTT 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975 166 NLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:PRK13537 168 GLDPQARHLMWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHAL 225
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 8-234 5.74e-38

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 135.35  E-value: 5.74e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQR---DICMVF 84
Cdd:TIGR03410   2 EVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERaraGIAYVP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   85 QSYALFPHMSLGDNVGYGLKmlGLPKAEiRKRVDEALELVD-LAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEP 163
Cdd:TIGR03410  82 QGREIFPRLTVEENLLTGLA--ALPRRS-RKIPDEIYELFPvLKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEP 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975  164 LSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMA 234
Cdd:TIGR03410 159 TEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDELDEDKVRRYLA 229
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 8-215 1.53e-37

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 132.34  E-value: 1.53e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFG--TNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTdrsiqqrdicmvfq 85
Cdd:cd03246    2 EVENVSFRYPgaEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADIS-------------- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALfphMSLGDNVGYglkmlgLPKaeirkrvDEALelvdlagFADRFVDQI-SGGQQQRVALARALILKPKVLLFDEPL 164
Cdd:cd03246   68 QWDP---NELGDHVGY------LPQ-------DDEL-------FSGSIAENIlSGGQRQRLGLARALYGNPRILVLDEPN 124

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 757596975 165 SNLDANLRRSMREKIRELQQQfNITSLYVTHdQSEAFAVSDMVLVMNKGKI 215
Cdd:cd03246  125 SHLDVEGERALNQAIAALKAA-GATRIVIAH-RPETLASADRILVLEDGRV 173
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
 10-231 1.53e-37

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 134.71  E-value: 1.53e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   10 KNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQR---DICMVFQS 86
Cdd:TIGR04406   5 ENLIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDITHLPMHERarlGIGYLPQE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   87 YALFPHMSLGDNVGYGLKMLG-LPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:TIGR04406  85 ASIFRKLTVEENIMAVLEIRKdLDRAEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKFILLDEPFA 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975  166 NLDANLRRSMREKIRELqQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASR 231
Cdd:TIGR04406 165 GVDPIAVGDIKKIIKHL-KERGIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPAEIVANEKVR 229
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 6-283 2.03e-37

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 138.44  E-value: 2.03e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   6 FVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMV 83
Cdd:PRK09536   3 MIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAasRRVASV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSYALFPHMSLGDNVGYG----LKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLL 159
Cdd:PRK09536  83 PQDTSLSFEFDVRQVVEMGrtphRSRFDTWTETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 160 FDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRfmASFmgD 239
Cdd:PRK09536 163 LDEPTASLDINHQVRTLELVRRLVDD-GKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTADTLR--AAF--D 237

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 757596975 240 ANIF----PATlthDSVNIFNYHLPRPAQLATDNTEITVGVRPEAITL 283
Cdd:PRK09536 238 ARTAvgtdPAT---GAPTVTPLPDPDRTEAAADTRVHVVGGGQPAARA 282
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 7-227 3.21e-37

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 133.82  E-value: 3.21e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGT---NTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDIC 81
Cdd:cd03249    1 IEFKNVSFRYPSrpdVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWlrSQIG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSYALFPhMSLGDNVGYglkmlGLPKAEiRKRVDEALELVDLAGFADRFVD-----------QISGGQQQRVALARA 150
Cdd:cd03249   81 LVSQEPVLFD-GTIAENIRY-----GKPDAT-DEEVEEAAKKANIHDFIMSLPDgydtlvgergsQLSGGQKQRIAIARA 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 151 LILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSeAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:cd03249  154 LLRNPKILLLDEATSALDAESEKLVQEALDRAMK--GRTTIVIAHRLS-TIRNADLIAVLQNGQVVEQGTHDELMAQ 227
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 21-237 4.45e-37

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 134.02  E-value: 4.45e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  21 VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGE------DV--TDRSIQQRDICMVFQSYALFPH 92
Cdd:PRK14246  25 ILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKvlyfgkDIfqIDAIKLRKEVGMVFQQPNPFPH 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  93 MSLGDNVGYGLKMLGLP-KAEIRKRVDEALELVDL-AGFADRF---VDQISGGQQQRVALARALILKPKVLLFDEPLSNL 167
Cdd:PRK14246 105 LSIYDNIAYPLKSHGIKeKREIKKIVEECLRKVGLwKEVYDRLnspASQLSGGQQQRLTIARALALKPKVLLMDEPTSMI 184

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 168 DANLRRSMREKIRELQQQfnITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFM 237
Cdd:PRK14246 185 DIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEKYV 252
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 9-216 8.16e-37

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 132.46  E-value: 8.16e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   9 LKNVTKR-FGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ-QRDICMVF-Q 85
Cdd:cd03267   23 LKSLFKRkYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRRKKfLRRIGVVFgQ 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:cd03267  103 KTQLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTI 182

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 757596975 166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIM 216
Cdd:cd03267  183 GLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLL 233
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 7-215 1.22e-36

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 131.56  E-value: 1.22e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF--GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT--DRSIQQRDICM 82
Cdd:cd03245    3 IEFRNVSFSYpnQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRqlDPADLRRNIGY 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFpHMSLGDNVgyglkMLGLPKAEIRkRVDEALELVDLAGFA-------DRFV----DQISGGQQQRVALARAL 151
Cdd:cd03245   83 VPQDVTLF-YGTLRDNI-----TLGAPLADDE-RILRAAELAGVTDFVnkhpnglDLQIgergRGLSGGQRQAVALARAL 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfnITSLYVTHDQSeAFAVSDMVLVMNKGKI 215
Cdd:cd03245  156 LNDPPILLLDEPTSAMDMNSEERLKERLRQLLGD--KTLIIITHRPS-LLDLVDRIIVMDSGRI 216
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 5-225 1.32e-36

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 133.43  E-value: 1.32e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   5 NFVELKNVTKRFGTNT-VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGE--DVTDRSIQQ--RD 79
Cdd:PRK13636   4 YILKVEELNYNYSDGThALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKpiDYSRKGLMKlrES 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 ICMVFQS--YALFPhMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:PRK13636  84 VGMVFQDpdNQLFS-ASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKV 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELY 225
Cdd:PRK13636 163 LVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF 230
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 7-228 1.32e-36

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 133.28  E-value: 1.32e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT-VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT-DRS--IQQRD-IC 81
Cdd:PRK13639   2 LETRDLKYSYPDGTeALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKyDKKslLEVRKtVG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSY--ALF-PhmSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVL 158
Cdd:PRK13639  82 IVFQNPddQLFaP--TVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEII 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 159 LFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK13639 160 VLDEPTSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDI 228
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 1-199 1.42e-36

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 131.76  E-value: 1.42e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHNFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT----DRSIQ 76
Cdd:PRK10247   2 QENSPLLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDIStlkpEIYRQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  77 QRDICmvFQSYALFphmslGDNVGYGLKmlgLPkAEIR-KRVDEALELVDLAGFA------DRFVDQISGGQQQRVALAR 149
Cdd:PRK10247  82 QVSYC--AQTPTLF-----GDTVYDNLI---FP-WQIRnQQPDPAIFLDDLERFAlpdtilTKNIAELSGGEKQRISLIR 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 757596975 150 ALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSE 199
Cdd:PRK10247 151 NLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDE 200
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
11-231 1.54e-36

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 135.00  E-value: 1.54e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  11 NVTKRFGTNTVidDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRS------IQQRDICMVF 84
Cdd:PRK11144   5 NFKQQLGDLCL--TVNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEkgiclpPEKRRIGYVF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMSLGDNVGYGLKmlglpkaeiRKRVDEALELVDLAGFA---DRFVDQISGGQQQRVALARALILKPKVLLFD 161
Cdd:PRK11144  83 QDARLFPHYKVRGNLRYGMA---------KSMVAQFDKIVALLGIEpllDRYPGSLSGGEKQRVAIGRALLTAPELLLMD 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 162 EPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASR 231
Cdd:PRK11144 154 EPLASLDLPRKRELLPYLERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWASSAMR 223
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 7-228 4.84e-36

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 131.31  E-value: 4.84e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGL-----EKPTEGRMFIDGEDVTDRSIQ----Q 77
Cdd:PRK14258   8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMnelesEVRVEGRVEFFNQNIYERRVNlnrlR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RDICMVFQSYALFPhMSLGDNVGYGLKMLGL-PKAEIRKRVDEALELVDLAGFADRFVDQ----ISGGQQQRVALARALI 152
Cdd:PRK14258  88 RQVSMVHPKPNLFP-MSVYDNVAYGVKIVGWrPKLEIDDIVESALKDADLWDEIKHKIHKsaldLSGGQQQRLCIARALA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVM--NKGKIMQL---GSPQELYRQ 227
Cdd:PRK14258 167 VKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFkgNENRIGQLvefGLTKKIFNS 246


                 .
gi 757596975 228 P 228
Cdd:PRK14258 247 P 247
nickel_nikD TIGR02770
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...
 22-230 5.42e-36

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131817 [Multi-domain]  Cd Length: 230  Bit Score: 130.18  E-value: 5.42e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKP----TEGRMFIDGEDVTDRSIQQRDICMVFQS--YALFPHMSL 95
Cdd:TIGR02770   2 VQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPgltqTSGEILLDGRPLLPLSIRGRHIATIMQNprTAFNPLFTM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   96 GDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFA---DRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLR 172
Cdd:TIGR02770  82 GNHAIETLRSLGKLSKQARALILEALEAVGLPDPEevlKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDLDVVNQ 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975  173 RSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPAS 230
Cdd:TIGR02770 162 ARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKH 219
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
7-215 7.83e-36

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 129.61  E-value: 7.83e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF-GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT---DRSIQ--QRDI 80
Cdd:PRK10908   2 IRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITrlkNREVPflRRQI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 CMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:PRK10908  82 GMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLA 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 161 DEPLSNLDANLrrsmREKIRELQQQFN---ITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:PRK10908 162 DEPTGNLDDAL----SEGILRLFEEFNrvgVTVLMATHDIGLISRRSYRMLTLSDGHL 215
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 5-224 1.93e-35

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 129.86  E-value: 1.93e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   5 NFVELKNVTKRFGTNT-VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QRDIC 81
Cdd:PRK13647   3 NIIEVEDLHFRYKDGTkALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKwvRSKVG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSY--ALFPhMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLL 159
Cdd:PRK13647  83 LVFQDPddQVFS-STVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIV 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 160 FDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:PRK13647 162 LDEPMAYLDPRGQETLMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLL 225
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
15-225 3.00e-35

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 129.36  E-value: 3.00e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  15 RFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGE--DVTDRSIQ--QRDICMVFQ--SYA 88
Cdd:PRK13638  10 RYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKplDYSKRGLLalRQQVATVFQdpEQQ 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  89 LFpHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLD 168
Cdd:PRK13638  90 IF-YTDIDSDIAFSLRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLD 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 169 ANLRRSMREKIRELQQQFNITSLyVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELY 225
Cdd:PRK13638 169 PAGRTQMIAIIRRIVAQGNHVII-SSHDIDLIYEISDAVYVLRQGQILTHGAPGEVF 224
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 22-224 4.06e-35

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 130.21  E-value: 4.06e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ-QRDICMVF-QSYALFPHMSLGDNv 99
Cdd:COG4586   38 VDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGYVPFKRRKEfARRIGVVFgQRSQLWWDLPAIDS- 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 100 gygLKML----GLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSM 175
Cdd:COG4586  117 ---FRLLkaiyRIPDAEYKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAI 193

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 757596975 176 REKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:COG4586  194 REFLKEYNRERGTTILLTSHDMDDIEALCDRVIVIDHGRIIYDGSLEEL 242
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 4-223 5.72e-35

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 134.99  E-value: 5.72e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    4 HNFVELKNVTKRF--GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT--DRSIQQRD 79
Cdd:TIGR03375 461 QGEIEFRNVSFAYpgQETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRqiDPADLRRN 540

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   80 ICMVFQSYALFpHMSLGDNVgyglkMLGLPKAEirkrvDEA-LELVDLAGfADRFVDQ---------------ISGGQQQ 143
Cdd:TIGR03375 541 IGYVPQDPRLF-YGTLRDNI-----ALGAPYAD-----DEEiLRAAELAG-VTEFVRRhpdgldmqigergrsLSGGQRQ 608

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  144 RVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSeAFAVSDMVLVMNKGKIMQLGSPQE 223
Cdd:TIGR03375 609 AVALARALLRDPPILLLDEPTSAMDNRSEERFKDRLKRWLA--GKTLVLVTHRTS-LLDLVDRIIVMDNGRIVADGPKDQ 685
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 7-210 6.45e-35

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 133.57  E-value: 6.45e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRF-GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT--DRSIQQRDICMV 83
Cdd:TIGR02857 322 LEFSGVSVAYpGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLAdaDADSWRDQIAWV 401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   84 FQSYALFPHmSLGDNVGYGLKmlGLPKAEIRkrvdEALELVDLAGFA-------DRFVDQ----ISGGQQQRVALARALI 152
Cdd:TIGR02857 402 PQHPFLFAG-TIAENIRLARP--DASDAEIR----EALERAGLDEFVaalpqglDTPIGEggagLSGGQAQRLALARAFL 474

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975  153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSEAfAVSDMVLVM 210
Cdd:TIGR02857 475 RDAPLLLLDEPTAHLDAETEAEVLEALRALAQ--GRTVLLVTHRLALA-ALADRIVVL 529
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 7-219 1.06e-34

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 126.49  E-value: 1.06e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF----------------------GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMF 64
Cdd:cd03220    1 IELENVSKSYptykggssslkklgilgrkgevGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  65 IDGedvtdrsiqqRDICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQR 144
Cdd:cd03220   81 VRG----------RVSSLLGLGGGFNPELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKAR 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 145 VALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNiTSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:cd03220  151 LAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGK-TVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
cbiO PRK13644
energy-coupling factor transporter ATPase;
7-233 1.11e-34

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 128.18  E-value: 1.11e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT-VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ---RDICM 82
Cdd:PRK13644   2 IRLENVSYSYPDGTpALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLQgirKLVGI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQS-YALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFD 161
Cdd:PRK13644  82 VFQNpETQFVGRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFD 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 162 EPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEaFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFM 233
Cdd:PRK13644 162 EVTSMLDPDSGIAVLERIKKLHEK-GKTIVYITHNLEE-LHDADRIIVMDRGKIVLEGEPENVLSDVSLQTL 231
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 1-227 1.47e-34

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 126.73  E-value: 1.47e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHnfVELKNVTKRF----------------------GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKP 58
Cdd:COG1134    1 MSSM--IEVENVSKSYrlyhepsrslkelllrrrrtrrEEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEP 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  59 TEGRMFIDGEdVTdrsiqqrdicmvfqsyALF-------PHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFAD 131
Cdd:COG1134   79 TSGRVEVNGR-VS----------------ALLelgagfhPELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFID 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 132 RFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMN 211
Cdd:COG1134  142 QPVKTYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRES-GRTVIFVSHSMGAVRRLCDRAIWLE 220

                        250
                 ....*....|....*....
gi 757596975 212 KGKIMQLGSPQE---LYRQ 227
Cdd:COG1134  221 KGRLVMDGDPEEviaAYEA 239
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 8-240 2.01e-34

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 126.64  E-value: 2.01e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDV---TDRSIQQRDICMVF 84
Cdd:PRK11300   7 SVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIeglPGHQIARMGVVRTF 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMS------------LGDNVGYGL-KMLGLPKAEiRKRVDEA---LELVDLAGFADRFVDQISGGQQQRVALA 148
Cdd:PRK11300  87 QHVRLFREMTvienllvaqhqqLKTGLFSGLlKTPAFRRAE-SEALDRAatwLERVGLLEHANRQAGNLAYGQQRRLEIA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK11300 166 RCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIRNNP 245

                        250
                 ....*....|..
gi 757596975 229 asRFMASFMGDA 240
Cdd:PRK11300 246 --DVIKAYLGEA 255
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 7-211 8.26e-34

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 125.28  E-value: 8.26e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLR-------LVAGLEkpTEGRMFIDGEDVTDRSIQ--- 76
Cdd:PRK14243  11 LRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRcfnrlndLIPGFR--VEGKVTFHGKNLYAPDVDpve 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  77 -QRDICMVFQSYALFPHmSLGDNVGYGLKMLGLpKAEIRKRVDEALELvdlAGFADRFVDQI-------SGGQQQRVALA 148
Cdd:PRK14243  89 vRRRIGMVFQKPNPFPK-SIYDNIAYGARINGY-KGDMDELVERSLRQ---AALWDEVKDKLkqsglslSGGQQQRLCIA 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNItsLYVTHDQSEAFAVSDMVLVMN 211
Cdd:PRK14243 164 RAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQYTI--IIVTHNMQQAARVSDMTAFFN 224
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 7-228 1.04e-33

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 125.69  E-value: 1.04e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT-VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMV 83
Cdd:PRK13652   4 IETRDLCYSYSGSKeALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREvrKFVGLV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSY--ALFPhMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFD 161
Cdd:PRK13652  84 FQNPddQIFS-PTVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLD 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 162 EPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK13652 163 EPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 7-227 1.27e-33

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 129.92  E-value: 1.27e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRF-----GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFI----DGEDVTDRSIQQ 77
Cdd:TIGR03269 280 IKVRNVSKRYisvdrGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVrvgdEWVDMTKPGPDG 359

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   78 RD-----ICMVFQSYALFPHMSLGDNVGYGLKmLGLPKaEIRKRvdEALELVDLAGFA--------DRFVDQISGGQQQR 144
Cdd:TIGR03269 360 RGrakryIGILHQEYDLYPHRTVLDNLTEAIG-LELPD-ELARM--KAVITLKMVGFDeekaeeilDKYPDELSEGERHR 435

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  145 VALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:TIGR03269 436 VALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEI 515


                  ...
gi 757596975  225 YRQ 227
Cdd:TIGR03269 516 VEE 518
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
7-224 2.39e-33

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 126.10  E-value: 2.39e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRS-IQQRDICMVFQ 85
Cdd:PRK13536  42 IDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARArLARARIGVVPQ 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDN-VGYGlKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPL 164
Cdd:PRK13536 122 FDNLDLEFTVRENlLVFG-RYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPT 200

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 165 SNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:PRK13536 201 TGLDPHARHLIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHAL 259
NHLM_micro_ABC2 TIGR03797
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ...
 7-228 2.87e-33

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274789 [Multi-domain]  Cd Length: 686  Bit Score: 130.08  E-value: 2.87e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTNT--VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QRDICM 82
Cdd:TIGR03797 452 IEVDRVTFRYRPDGplILDDVSLQIEPGEFVAIVGPSGSGKSTLLRLLLGFETPESGSVFYDGQDLAGLDVQavRRQLGV 531

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   83 VFQSYALFPHmSLGDNVGYGLKMlglpkaeirkRVDEALELVDLAGFAD----------RFVDQ----ISGGQQQRVALA 148
Cdd:TIGR03797 532 VLQNGRLMSG-SIFENIAGGAPL----------TLDEAWEAARMAGLAEdirampmgmhTVISEgggtLSGGQRQRLLIA 600

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRELqqqfNITSLYVTHDQS---EAfavsDMVLVMNKGKIMQLGSPQELY 225
Cdd:TIGR03797 601 RALVRKPRILLFDEATSALDNRTQAIVSESLERL----KVTRIVIAHRLStirNA----DRIYVLDAGRVVQQGTYDELM 672


                  ...
gi 757596975  226 RQP 228
Cdd:TIGR03797 673 ARE 675
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
15-200 1.47e-32

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 120.03  E-value: 1.47e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  15 RFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEdvtdrsiqqRDICMVFQSYAL---FP 91
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGG---------ARVAYVPQRSEVpdsLP 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  92 hMSLGDNVGYGL----KMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNL 167
Cdd:NF040873  72 -LTVRDLVAMGRwarrGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGL 150

                        170       180       190
                 ....*....|....*....|....*....|...
gi 757596975 168 DANLRRSMREKIRELQQQfNITSLYVTHDQSEA 200
Cdd:NF040873 151 DAESRERIIALLAEEHAR-GATVVVVTHDLELV 182
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
7-240 1.59e-32

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 122.21  E-value: 1.59e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT---------VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT--DRSI 75
Cdd:PRK15112   5 LEVRNLSKTFRYRTgwfrrqtveAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHfgDYSY 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  76 QQRDICMVFQ--SYALFPHMSLGDNVGYGLKM-LGLPKAEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARAL 151
Cdd:PRK15112  85 RSQRIRMIFQdpSTSLNPRQRISQILDFPLRLnTDLEPEQREKQIIETLRQVGLlPDHASYYPHMLAPGQKQRLGLARAL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP--- 228
Cdd:PRK15112 165 ILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLASPlhe 244

                        250
                 ....*....|...
gi 757596975 229 -ASRFMASFMGDA 240
Cdd:PRK15112 245 lTKRLIAGHFGEA 257
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 6-224 1.72e-32

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 120.79  E-value: 1.72e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   6 FVELKNVTKRF-GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICM 82
Cdd:cd03254    2 EIEFENVNFSYdEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSlrSMIGV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFPHmSLGDNVgyglkMLGLPKAEiRKRVDEALELVDlagfADRFVDQ---------------ISGGQQQRVAL 147
Cdd:cd03254   82 VLQDTFLFSG-TIMENI-----RLGRPNAT-DEEVIEAAKEAG----AHDFIMKlpngydtvlgenggnLSQGERQLLAI 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 148 ARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSeAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:cd03254  151 ARAMLRDPKILILDEATSNIDTETEKLIQEALEKLMK--GRTSIIIAHRLS-TIKNADKILVLDDGKIIEEGTHDEL 224
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 7-227 5.05e-32

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 119.90  E-value: 5.05e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT--VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDV--TDRSIQQRDICM 82
Cdd:cd03252    1 ITFEHVRFRYKPDGpvILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLalADPAWLRRQVGV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFpHMSLGDNVGyglkmLGLPKAEIRkRVDEALELVDLAGFADRF---VDQI--------SGGQQQRVALARAL 151
Cdd:cd03252   81 VLQENVLF-NRSIRDNIA-----LADPGMSME-RVIEAAKLAGAHDFISELpegYDTIvgeqgaglSGGQRQRIAIARAL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSeAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:cd03252  154 IHNPRILIFDEATSALDYESEHAIMRNMHDICA--GRTVIIIAHRLS-TVKNADRIIVMEKGRIVEQGSHDELLAE 226
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 11-239 1.96e-31

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 119.43  E-value: 1.96e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  11 NVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--------QRDICM 82
Cdd:PRK14271  26 NLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVLLGGRSIFnyrdvlefRRRVGM 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFPhMSLGDNVGYGLKMLGL-PKAEIRKRVDEALELVDL-AGFADRFVD---QISGGQQQRVALARALILKPKV 157
Cdd:PRK14271 106 LFQRPNPFP-MSIMDNVLAGVRAHKLvPRKEFRGVAQARLTEVGLwDAVKDRLSDspfRLSGGQQQLLCLARTLAVNPEV 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQfnITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP----ASRFM 233
Cdd:PRK14271 185 LLLDEPTSALDPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPkhaeTARYV 262


                 ....*.
gi 757596975 234 ASFMGD 239
Cdd:PRK14271 263 AGLSGD 268
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 7-229 4.87e-31

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 119.57  E-value: 4.87e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT-----VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFI---------DGEDVTD 72
Cdd:PRK13631  22 LRVKNLYCVFDEKQenelvALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVgdiyigdkkNNHELIT 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  73 RSIQQ---------RDICMVFQ--SYALFPHmSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDL-AGFADRFVDQISGG 140
Cdd:PRK13631 102 NPYSKkiknfkelrRRVSMVFQfpEYQLFKD-TIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLdDSYLERSPFGLSGG 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 141 QQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGS 220
Cdd:PRK13631 181 QKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKAN-NKTVFVITHTMEHVLEVADEVIVMDKGKILKTGT 259


                 ....*....
gi 757596975 221 PQELYRQPA 229
Cdd:PRK13631 260 PYEIFTDQH 268
type_I_sec_HlyB TIGR01846
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ...
 7-227 9.00e-31

type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273831 [Multi-domain]  Cd Length: 694  Bit Score: 122.93  E-value: 9.00e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTNT--VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDV--TDRSIQQRDICM 82
Cdd:TIGR01846 456 ITFENIRFRYAPDSpeVLSNLNLDIKPGEFIGIVGPSGSGKSTLTKLLQRLYTPQHGQVLVDGVDLaiADPAWLRRQMGV 535

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   83 VFQSYALFPHmSLGDNVGygLKMLGLPKAEIR--KRVDEALELVDL--AGFADRFVDQ---ISGGQQQRVALARALILKP 155
Cdd:TIGR01846 536 VLQENVLFSR-SIRDNIA--LCNPGAPFEHVIhaAKLAGAHDFISElpQGYNTEVGEKganLSGGQRQRIAIARALVGNP 612

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975  156 KVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSeAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:TIGR01846 613 RILIFDEATSALDYESEALIMRNMREICR--GRTVIIIAHRLS-TVRACDRIIVLEKGQIAESGRHEELLAL 681
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
7-224 1.43e-30

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 116.65  E-value: 1.43e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGL---EKPTEGRMFIDGEDVTDRSIQQRDI--- 80
Cdd:PRK09984   5 IRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgDKSAGSHIELLGRTVQREGRLARDIrks 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 ----CMVFQSYALFPHMSLGDNVGYGlkMLGLP----------KAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVA 146
Cdd:PRK09984  85 rantGYIFQQFNLVNRLSVLENVLIG--ALGSTpfwrtcfswfTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVA 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 147 LARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:PRK09984 163 IARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQF 240
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 7-231 7.26e-30

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 114.49  E-value: 7.26e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGL-----EKPTEGRMFIDGEDV----TDRSIQQ 77
Cdd:PRK14239   6 LQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndlnpEVTITGSIVYNGHNIysprTDTVDLR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RDICMVFQSYALFPhMSLGDNVGYGLKMLGLPKAEIrkrVDEALElVDLAGFA------DRFVDQ---ISGGQQQRVALA 148
Cdd:PRK14239  86 KEIGMVFQQPNPFP-MSIYENVVYGLRLKGIKDKQV---LDEAVE-KSLKGASiwdevkDRLHDSalgLSGGQQQRVCIA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFniTSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK14239 161 RVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDY--TMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFMNP 238


                 ...
gi 757596975 229 ASR 231
Cdd:PRK14239 239 KHK 241
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 7-215 1.58e-29

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 111.75  E-value: 1.58e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRfgtnTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRD---ICMV 83
Cdd:cd03215    5 LEVRGLSVK----GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAIragIAYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 ---FQSYALFPHMSLGDNvgyglkmLGLPkaeirkrvdealelvdlagfadrfvDQISGGQQQRVALARALILKPKVLLF 160
Cdd:cd03215   81 pedRKREGLVLDLSVAEN-------IALS-------------------------SLLSGGNQQKVVLARWLARDPRVLIL 128

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 161 DEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:cd03215  129 DEPTRGVDVGAKAEIYRLIRELADA-GKAVLLISSELDELLGLCDRILVMYEGRI 182
cbiO PRK13649
energy-coupling factor transporter ATPase;
7-227 1.83e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 114.07  E-value: 1.83e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVID-----DLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRS----IQQ 77
Cdd:PRK13649   3 INLQNVSYTYQAGTPFEgralfDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSknkdIKQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 --RDICMVFQ--SYALFPHMSLGDnVGYGLKMLGLPKAEIRKRVDEALELVdlaGFADRFVDQ----ISGGQQQRVALAR 149
Cdd:PRK13649  83 irKKVGLVFQfpESQLFEETVLKD-VAFGPQNFGVSQEEAEALAREKLALV---GISESLFEKnpfeLSGGQMRRVAIAG 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 150 ALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:PRK13649 159 ILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQS-GMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQD 235
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
21-196 2.33e-29

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 112.60  E-value: 2.33e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  21 VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRS------IQQRDICMVFQSYALFPHMS 94
Cdd:PRK11629  24 VLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSsaakaeLRNQKLGFIYQFHHLLPDFT 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  95 LGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRS 174
Cdd:PRK11629 104 ALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADS 183

                        170       180
                 ....*....|....*....|..
gi 757596975 175 MREKIRELQQQFNITSLYVTHD 196
Cdd:PRK11629 184 IFQLLGELNRLQGTAFLVVTHD 205
cbiO PRK13646
energy-coupling factor transporter ATPase;
22-227 3.10e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 113.72  E-value: 3.10e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD-------RSIQQRdICMVFQsyalFPHMS 94
Cdd:PRK13646  23 IHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHktkdkyiRPVRKR-IGMVFQ----FPESQ 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  95 L-GDNVG----YGLKMLGLPKAEIRkrvDEALELVDLAGFADRFVD----QISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:PRK13646  98 LfEDTVEreiiFGPKNFKMNLDEVK---NYAHRLLMDLGFSRDVMSqspfQMSGGQMRKIAIVSILAMNPDIIVLDEPTA 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:PRK13646 175 GLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKD 236
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
8-230 9.29e-29

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 116.75  E-value: 9.29e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRF----GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD------RSIQQ 77
Cdd:PRK10535   6 ELKDIRRSYpsgeEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATldadalAQLRR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RDICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:PRK10535  86 EHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQV 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNiTSLYVTHDQSEAfAVSDMVLVMNKGKIMQlGSPQELYRQPAS 230
Cdd:PRK10535 166 ILADEPTGALDSHSGEEVMAILHQLRDRGH-TVIIVTHDPQVA-AQAERVIEIRDGEIVR-NPPAQEKVNVAG 235
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 7-228 1.52e-28

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 116.36  E-value: 1.52e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGT---NTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT--DRSIQQRDIC 81
Cdd:TIGR00958 479 IEFQDVSFSYPNrpdVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVqyDHHYLHRQVA 558

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   82 MVFQSYALFPHmSLGDNVGYGLKMLglPKAEIRKRVDEAlelvdlagFADRFV---------------DQISGGQQQRVA 146
Cdd:TIGR00958 559 LVGQEPVLFSG-SVRENIAYGLTDT--PDEEIMAAAKAA--------NAHDFImefpngydtevgekgSQLSGGQKQRIA 627

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  147 LARALILKPKVLLFDEPLSNLDANLRRSmrekIRELQQQFNITSLYVTHDQSEAfAVSDMVLVMNKGKIMQLGSPQELYR 226
Cdd:TIGR00958 628 IARALVRKPRVLILDEATSALDAECEQL----LQESRSRASRTVLLIAHRLSTV-ERADQILVLKKGSVVEMGTHKQLME 702


                  ..
gi 757596975  227 QP 228
Cdd:TIGR00958 703 DQ 704
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 7-227 1.63e-28

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 116.07  E-value: 1.63e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVtkRFGTN---TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVtdRSIQQ----RD 79
Cdd:COG5265  358 VRFENV--SFGYDperPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDI--RDVTQaslrAA 433

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 ICMVFQSYALFpHMSLGDNVGYGlkMLGLPKAEIRkrvdEALELVDLAGFADRFVDQI-----------SGGQQQRVALA 148
Cdd:COG5265  434 IGIVPQDTVLF-NDTIAYNIAYG--RPDASEEEVE----AAARAAQIHDFIESLPDGYdtrvgerglklSGGEKQRVAIA 506

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQS---EAfavsDMVLVMNKGKIMQLGSPQELY 225
Cdd:COG5265  507 RTLLKNPPILIFDEATSALDSRTERAIQAALREVAR--GRTTLVIAHRLStivDA----DEILVLEAGRIVERGTHAELL 580


                 ..
gi 757596975 226 RQ 227
Cdd:COG5265  581 AQ 582
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 17-223 2.41e-28

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 115.23  E-value: 2.41e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  17 GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT--DRSIQQRDICMVFQSYALFPHmS 94
Cdd:COG4618  343 SKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSqwDREELGRHIGYLPQDVELFDG-T 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  95 LGDNVGyglkMLGLPKAEirkRVDEALELVDLAGFADRFVD-----------QISGGQQQRVALARALILKPKVLLFDEP 163
Cdd:COG4618  422 IAENIA----RFGDADPE---KVVAAAKLAGVHEMILRLPDgydtrigeggaRLSGGQRQRIGLARALYGDPRLVVLDEP 494

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 164 LSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSeAFAVSDMVLVMNKGKIMQLGSPQE 223
Cdd:COG4618  495 NSNLDDEGEAALAAAIRALKAR-GATVVVITHRPS-LLAAVDKLLVLRDGRVQAFGPRDE 552
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 10-224 2.91e-28

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 109.98  E-value: 2.91e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  10 KNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQR---DICMVFQS 86
Cdd:PRK10895   7 KNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARarrGIGYLPQE 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGLKMLGLPKAEIRK-RVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:PRK10895  87 ASIFRRLSVYDNLMAVLQIRDDLSAEQREdRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFA 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975 166 NLDANLRRSMREKIRELqQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:PRK10895 167 GVDPISVIDIKRIIEHL-RDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEI 224
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 5-236 3.26e-28

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 110.20  E-value: 3.26e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   5 NFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGrmfidgedVTDRSIQQRdICMVF 84
Cdd:PRK09544   3 SLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEG--------VIKRNGKLR-IGYVP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMSLgdNVGYGLKML-GLPKAEIRKrvdeALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEP 163
Cdd:PRK09544  74 QKLYLDTTLPL--TVNRFLRLRpGTKKEDILP----ALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLDEP 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 164 LSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNkGKIMQLGSPQELYRQPasRFMASF 236
Cdd:PRK09544 148 TQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEVLCLN-HHICCSGTPEVVSLHP--EFISMF 217
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 21-219 3.27e-28

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 109.28  E-value: 3.27e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  21 VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGL---EKPTEGRMFIDGEDVtDRSIQQRDICMVFQSYALFPHMSLGD 97
Cdd:cd03234   22 ILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRvegGGTTSGQILFNGQPR-KPDQFQKCVAYVRQDDILLPGLTVRE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  98 NVGYGLKMLG---LPKAEIRKRV-DEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRR 173
Cdd:cd03234  101 TLTYTAILRLprkSSDAIRKKRVeDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFTAL 180

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 757596975 174 SMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:cd03234  181 NLVSTLSQLARRNRIVILTIHQPRSDLFRLFDRILLLSSGEIVYSG 226
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 7-223 6.42e-28

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 110.56  E-value: 6.42e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT-----VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRM---FIDGED--------- 69
Cdd:PRK13651   3 IKVKNIVKIFNKKLptelkALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewiFKDEKNkkktkekek 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  70 -VTDRSIQ-------------QRDICMVFQ--SYALFPHMSLGDnVGYGLKMLGLPKAEIRKRVDEALELVDL-AGFADR 132
Cdd:PRK13651  83 vLEKLVIQktrfkkikkikeiRRRVGVVFQfaEYQLFEQTIEKD-IIFGPVSMGVSKEEAKKRAAKYIELVGLdESYLQR 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 133 FVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNK 212
Cdd:PRK13651 162 SPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDLDNVLEWTKRTIFFKD 240

                        250
                 ....*....|.
gi 757596975 213 GKIMQLGSPQE 223
Cdd:PRK13651 241 GKIIKDGDTYD 251
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 8-170 6.47e-28

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 107.83  E-value: 6.47e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDV-TDRSIQQRDICMVFQS 86
Cdd:TIGR01189   2 AARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLaEQRDEPHENILYLGHL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   87 YALFPHMSLGDNVGYGLKMLGlpkaEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:TIGR01189  82 PGLKPELSALENLHFWAAIHG----GAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTA 157


                  ....
gi 757596975  167 LDAN 170
Cdd:TIGR01189 158 LDKA 161
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
10-224 7.53e-28

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 109.69  E-value: 7.53e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  10 KNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMVFQSY 87
Cdd:PRK10253  11 EQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEvaRRIGLLAQNA 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  88 ALFPHMSLGDNVGYG----LKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEP 163
Cdd:PRK10253  91 TTPGDITVQELVARGryphQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEP 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 164 LSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:PRK10253 171 TTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEI 231
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 9-196 7.58e-28

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 113.62  E-value: 7.58e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   9 LKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGeDVTdrsiqqrdICMVFQSYA 88
Cdd:COG0488    1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPK-GLR--------IGYLPQEPP 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  89 LFPHMSLGDNVGYGLKMLGLPKAEIRK-------------RVDEALELVD--------------LAGF------ADRFVD 135
Cdd:COG0488   72 LDDDLTVLDTVLDGDAELRALEAELEEleaklaepdedleRLAELQEEFEalggweaearaeeiLSGLgfpeedLDRPVS 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 136 QISGGQQQRVALARALILKPKVLLFDEPLSNLDANlrrsMREKIRELQQQFNITSLYVTHD 196
Cdd:COG0488  152 ELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLE----SIEWLEEFLKNYPGTVLVVSHD 208
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 1-200 8.49e-28

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 108.33  E-value: 8.49e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHNFVELKNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ 76
Cdd:PRK10584   1 MPAENIVEVHHLKKSVGQGehelSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  77 QR------DICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARA 150
Cdd:PRK10584  81 ARaklrakHVGFVFQSFMLIPTLNALENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARA 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 757596975 151 LILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEA 200
Cdd:PRK10584 161 FNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLA 210
cbiO PRK13643
energy-coupling factor transporter ATPase;
24-227 9.43e-28

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 109.82  E-value: 9.43e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  24 DLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ------RDICMVFQ--SYALFPHMSL 95
Cdd:PRK13643  24 DIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKeikpvrKKVGVVFQfpESQLFEETVL 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  96 GDnVGYGLKMLGLPKAEIRKRVDEALELVDLAG-FADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRS 174
Cdd:PRK13643 104 KD-VAFGPQNFGIPKEKAEKIAAEKLEMVGLADeFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKARIE 182

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 757596975 175 MReKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:PRK13643 183 MM-QLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQE 234
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 7-236 1.55e-27

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 112.59  E-value: 1.55e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLE--KPTEGRM--------------------- 63
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDqyEPTSGRIiyhvalcekcgyverpskvge 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   64 ---------------FIDGEDVTDRSIQQRDICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAG 128
Cdd:TIGR03269  81 pcpvcggtlepeevdFWNLSDKLRRRIRKRIAIMLQRTFALYGDDTVLDNVLEALEEIGYEGKEAVGRAVDLIEMVQLSH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  129 FADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVL 208
Cdd:TIGR03269 161 RITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKAI 240

                         250       260
                  ....*....|....*....|....*...
gi 757596975  209 VMNKGKIMQLGSPQELyrqpASRFMASF 236
Cdd:TIGR03269 241 WLENGEIKEEGTPDEV----VAVFMEGV 264
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
9-228 1.70e-27

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 108.72  E-value: 1.70e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   9 LKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QRDICMVFQS 86
Cdd:PRK10575  14 LRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKafARKVAYLPQQ 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YALFPHMSLGDNVGYGL----KMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDE 162
Cdd:PRK10575  94 LPAAEGMTVRELVAIGRypwhGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDE 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 163 PLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK10575 174 PTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGE 239
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 20-222 1.91e-27

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 112.59  E-value: 1.91e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  20 TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFI-DGEDvtdrsiqqrdicMVF---QSYalFPHMSL 95
Cdd:COG4178  377 PLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARpAGAR------------VLFlpqRPY--LPLGTL 442

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  96 GDNVGYGLKMLGLPKAEIRkrvdEALELVDLAGFADRFvDQI-------SGGQQQRVALARALILKPKVLLFDEPLSNLD 168
Cdd:COG4178  443 REALLYPATAEAFSDAELR----EALEAVGLGHLAERL-DEEadwdqvlSLGEQQRLAFARLLLHKPDWLFLDEATSALD 517

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 757596975 169 ANLRRSMREKIRElqQQFNITSLYVTHdQSEAFAVSDMVLVMNKGKIMQLGSPQ 222
Cdd:COG4178  518 EENEAALYQLLRE--ELPGTTVISVGH-RSTLAAFHDRVLELTGDGSWQLLPAE 568
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 7-215 3.09e-27

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 111.70  E-value: 3.09e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIdGEDVTdrsI----QQRDicm 82
Cdd:COG0488  316 LELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETVK---IgyfdQHQE--- 388

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 vfqsyALFPHMSLGDNVGYGLKmlGLPKAEIRKRvdealelvdLAGF------ADRFVDQISGGQQQRVALARALILKPK 156
Cdd:COG0488  389 -----ELDPDKTVLDELRDGAP--GGTEQEVRGY---------LGRFlfsgddAFKPVGVLSGGEKARLALAKLLLSPPN 452

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 157 VLLFDEPLSNLDANlrrsMREKIRELQQQFNITSLYVTHDqsEAF--AVSDMVLVMNKGKI 215
Cdd:COG0488  453 VLLLDEPTNHLDIE----TLEALEEALDDFPGTVLLVSHD--RYFldRVATRILEFEDGGV 507
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 22-237 3.76e-27

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 112.26  E-value: 3.76e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDV---TDRSIQ--QRDICMVFQS-YA-LFPHMS 94
Cdd:PRK10261 340 VEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIdtlSPGKLQalRRDIQFIFQDpYAsLDPRQT 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  95 LGDNVGYGLKMLGLPKAE-IRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLR 172
Cdd:PRK10261 420 VGDSIMEPLRVHGLLPGKaAAARVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIR 499

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 173 RSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFM 237
Cdd:PRK10261 500 GQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLM 564
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 7-214 4.51e-27

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 104.07  E-value: 4.51e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGedvtdrsiqqrdicmvfqs 86
Cdd:cd03221    1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGS------------------- 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 yalfphmslGDNVGYglkmlglpkaeirkrvdealelvdlagfadrfVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
Cdd:cd03221   62 ---------TVKIGY--------------------------------FEQLSGGEKMRLALAKLLLENPNLLLLDEPTNH 100

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 757596975 167 LDANlrrsMREKIRELQQQFNITSLYVTHDQseAF--AVSDMVLVMNKGK 214
Cdd:cd03221  101 LDLE----SIEALEEALKEYPGTVILVSHDR--YFldQVATKIIELEDGK 144
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 3-196 4.52e-27

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 111.30  E-value: 4.52e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    3 QHNFVELKNVTKRF-GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT--DRSIQQRD 79
Cdd:TIGR02868 331 GKPTLELRDLSAGYpGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSslDQDEVRRR 410

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   80 ICMVFQSYALFpHMSLGDNVgyglkMLGLPKA---EIRkrvdEALELVDLAGFADRFVD-----------QISGGQQQRV 145
Cdd:TIGR02868 411 VSVCAQDAHLF-DTTVRENL-----RLARPDAtdeELW----AALERVGLADWLRALPDgldtvlgeggaRLSGGERQRL 480

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 757596975  146 ALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFniTSLYVTHD 196
Cdd:TIGR02868 481 ALARALLADAPILLLDEPTEHLDAETADELLEDLLAALSGR--TVVLITHH 529
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
7-227 4.96e-27

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 112.14  E-value: 4.96e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSiQQRDICmvfQS 86
Cdd:NF033858   2 ARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADAR-HRRAVC---PR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  87 YA---------LFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:NF033858  78 IAympqglgknLYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDL 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTH---DQSEAFavsDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:NF033858 158 LILDEPTTGVDPLSRRQFWELIDRIRAERPGMSVLVATaymEEAERF---DWLVAMDAGRVLATGTPAELLAR 227
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 8-224 5.12e-27

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 106.69  E-value: 5.12e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEK--PTEGRMFIDGEDVTDRSIQQR---DICM 82
Cdd:COG0396    2 EIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKyeVTSGSILLDGEDILELSPDERaraGIFL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFPHMSLGD--NVGYGLKMLGLPKA-EIRKRVDEALELVDLA-GFADRFVDQ-ISGGQQQRVALARALILKPKV 157
Cdd:COG0396   82 AFQYPVEIPGVSVSNflRTALNARRGEELSArEFLKLLKEKMKELGLDeDFLDRYVNEgFSGGEKKRNEILQMLLLEPKL 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQS-EAFAVSDMVLVMNKGKIMQLGSPqEL 224
Cdd:COG0396  162 AILDETDSGLDIDALRIVAEGVNKLRSP-DRGILIITHYQRiLDYIKPDFVHVLVDGRIVKSGGK-EL 227
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
7-237 7.37e-27

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 111.21  E-value: 7.37e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF-GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QRDICMV 83
Cdd:PRK13657 335 VEFDDVSFSYdNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRAslRRNIAVV 414

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSYALFpHMSLGDNVgyglkMLGLPKA---EIRkrvdEALELVDLAGFADRFVD-----------QISGGQQQRVALAR 149
Cdd:PRK13657 415 FQDAGLF-NRSIEDNI-----RVGRPDAtdeEMR----AAAERAQAHDFIERKPDgydtvvgergrQLSGGERQRLAIAR 484

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 150 ALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQS---EAfavsDMVLVMNKGKIMQLGSPQELYr 226
Cdd:PRK13657 485 ALLKDPPILILDEATSALDVETEAKVKAALDELMK--GRTTFIIAHRLStvrNA----DRILVFDNGRVVESGSFDELV- 557

                        250
                 ....*....|....*
gi 757596975 227 QPASRFM----ASFM 237
Cdd:PRK13657 558 ARGGRFAallrAQGM 572
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
8-215 1.46e-26

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 109.72  E-value: 1.46e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRfgtnTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ---RDICMV- 83
Cdd:COG1129  258 EVEGLSVG----GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRDairAGIAYVp 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 --FQSYALFPHMSLGDNVGYG-LKMLG----LPKAEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARALILKP 155
Cdd:COG1129  334 edRKGEGLVLDLSIRENITLAsLDRLSrgglLDRRRERALAEEYIKRLRIkTPSPEQPVGNLSGGNQQKVVLAKWLATDP 413

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 156 KVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:COG1129  414 KVLILDEPTRGIDVGAKAEIYRLIRELAAE-GKAVIVISSELPELLGLSDRILVMREGRI 472
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 7-215 1.83e-26

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 103.78  E-value: 1.83e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTnTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGL--EKPTEGRMFIDGEDVTDRSIQQRdICMVF 84
Cdd:cd03213   11 VTVKSSPSKSGK-QLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRrtGLGVSGEVLINGRPLDKRSFRKI-IGYVP 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMSLGDNVGYGLKMLGlpkaeirkrvdealelvdlagfadrfvdqISGGQQQRVALARALILKPKVLLFDEPL 164
Cdd:cd03213   89 QDDILHPTLTVRETLMFAAKLRG-----------------------------LSGGERKRVSIALELVSNPSLLFLDEPT 139

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 757596975 165 SNLDANLRRSMREKIRELQQQfNITSLYVTHD-QSEAFAVSDMVLVMNKGKI 215
Cdd:cd03213  140 SGLDSSSALQVMSLLRRLADT-GRTIICSIHQpSSEIFELFDKLLLLSQGRV 190
cbiO PRK13641
energy-coupling factor transporter ATPase;
7-228 1.89e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 106.45  E-value: 1.89e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTV-----IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT----DRSIQ- 76
Cdd:PRK13641   3 IKFENVDYIYSPGTPmekkgLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITpetgNKNLKk 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  77 -QRDICMVFQsyalFPHMSLGDN-----VGYGLKMLGLPKAEIRkrvDEALELVDLAGFADRFVD----QISGGQQQRVA 146
Cdd:PRK13641  83 lRKKVSLVFQ----FPEAQLFENtvlkdVEFGPKNFGFSEDEAK---EKALKWLKKVGLSEDLISkspfELSGGQMRRVA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 147 LARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNiTSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYR 226
Cdd:PRK13641 156 IAGVMAYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQKAGH-TVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFS 234


                 ..
gi 757596975 227 QP 228
Cdd:PRK13641 235 DK 236
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 17-232 2.23e-26

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 109.41  E-value: 2.23e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  17 GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTT----VLRLVAglekpTEGRMFIDGEDVTDRSIQQ-----RDICMVFQ-- 85
Cdd:PRK15134 297 DHNVVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLIN-----SQGEIWFDGQPLHNLNRRQllpvrHRIQVVFQdp 371

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKM--LGLPKAEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARALILKPKVLLFDE 162
Cdd:PRK15134 372 NSSLNPRLNVLQIIEEGLRVhqPTLSAAQREQQVIAVMEEVGLdPETRHRYPAEFSGGQRQRIAIARALILKPSLIILDE 451

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 163 PLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRF 232
Cdd:PRK15134 452 PTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEY 521
cbiO PRK13645
energy-coupling factor transporter ATPase;
9-225 6.33e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 105.09  E-value: 6.33e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   9 LKNVTKRFGTNT-----VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIdGEDVTDRSIQQ------ 77
Cdd:PRK13645   9 LDNVSYTYAKKTpfefkALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIV-GDYAIPANLKKikevkr 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 --RDICMVFQ--SYALFPHmSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLA-GFADRFVDQISGGQQQRVALARALI 152
Cdd:PRK13645  88 lrKEIGLVFQfpEYQLFQE-TIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLPeDYVKRSPFELSGGQKRRVALAGIIA 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELY 225
Cdd:PRK13645 167 MDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIF 239
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 7-215 9.81e-26

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 102.93  E-value: 9.81e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNT---VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT--DRSIQQRDIC 81
Cdd:cd03248   12 VKFQNVTFAYPTRPdtlVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISqyEHKYLHSKVS 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSYALFPHmSLGDNVGYGLKmlGLPKAEIRKRVDEALELVDLAGFADRFVD-------QISGGQQQRVALARALILK 154
Cdd:cd03248   92 LVGQEPVLFAR-SLQDNIAYGLQ--SCSFECVKEAAQKAHAHSFISELASGYDTevgekgsQLSGGQKQRVAIARALIRN 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 155 PKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSeAFAVSDMVLVMNKGKI 215
Cdd:cd03248  169 PQVLILDEATSALDAESEQQVQQALYDWPE--RRTVLVIAHRLS-TVERADQILVLDGGRI 226
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 25-228 1.16e-25

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 107.62  E-value: 1.16e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  25 LSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLeKPTEGRMFIDGEDVTDRSIQQ--RDICMVFQSYALFpHMSLGDNVgyg 102
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTSLLNALLGF-LPYQGSLKINGIELRELDPESwrKHLSWVGQNPQLP-HGTLRDNV--- 443

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 103 lkMLGLPKAEiRKRVDEALELVDLAGFADRFV--------DQ---ISGGQQQRVALARALILKPKVLLFDEPLSNLDANL 171
Cdd:PRK11174 444 --LLGNPDAS-DEQLQQALENAWVSEFLPLLPqgldtpigDQaagLSVGQAQRLALARALLQPCQLLLLDEPTASLDAHS 520

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 172 -RRSMREKIRELQQQfniTSLYVTHdQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK11174 521 eQLVMQALNAASRRQ---TTLMVTH-QLEDLAQWDQIWVMQDGQIVQQGDYAELSQAG 574
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 8-214 1.42e-25

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 106.94  E-value: 1.42e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLeKPT---EGRMFIDGEDVTDRSI---QQRDIC 81
Cdd:PRK13549   7 EMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGV-YPHgtyEGEIIFEGEELQASNIrdtERAGIA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSYALFPHMSLGDNVgyglkMLGlpkAEIRK-----------RVDEALELVDLAGFADRFVDQISGGQQQRVALARA 150
Cdd:PRK13549  86 IIHQELALVKELSVLENI-----FLG---NEITPggimdydamylRAQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKA 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757596975 151 LILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGK 214
Cdd:PRK13549 158 LNKQARLLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGR 220
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 7-224 1.56e-25

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 107.52  E-value: 1.56e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTNT-VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT--DRSIQQRDICMV 83
Cdd:TIGR01193 474 IVINDVSYSYGYGSnILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKdiDRHTLRQFINYL 553

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   84 FQSYALFPHmSLGDNVGYGLKmlglPKAEIRKrVDEALELVDLA--------GFADRFVDQ---ISGGQQQRVALARALI 152
Cdd:TIGR01193 554 PQEPYIFSG-SILENLLLGAK----ENVSQDE-IWAACEIAEIKddienmplGYQTELSEEgssISGGQKQRIALARALL 627

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975  153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfniTSLYVTHDQSEAfAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:TIGR01193 628 TDSKVLILDESTSNLDTITEKKIVNNLLNLQDK---TIIFVAHRLSVA-KQSDKIIVLDHGKIIEQGSHDEL 695
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
7-227 2.44e-25

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 107.13  E-value: 2.44e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRD-ICMVFQ 85
Cdd:NF033858 267 IEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGDIATRRrVGYMSQ 346

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:NF033858 347 AFSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTS 426

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAfAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:NF033858 427 GVDPVARDMFWRLLIELSREDGVTIFISTHFMNEA-ERCDRISLMHAGRVLASDTPAALVAA 487
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 8-170 5.50e-25

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 100.26  E-value: 5.50e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTdrsiQQRDIcmVFQSY 87
Cdd:cd03231    2 EADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLD----FQRDS--IARGL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  88 ALFPHMSlgdnvgyGLKMLGLPKAEIR--------KRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLL 159
Cdd:cd03231   76 LYLGHAP-------GIKTTLSVLENLRfwhadhsdEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWI 148

                        170
                 ....*....|.
gi 757596975 160 FDEPLSNLDAN 170
Cdd:cd03231  149 LDEPTTALDKA 159
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 7-196 5.74e-25

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 105.40  E-value: 5.74e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIdGEDVTDRSI-QQRDicmvfq 85
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETVKLAYVdQSRD------ 395

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   86 syALFPHMSLGDNVGYGLKMLGLPKAEIRKRVdealeLVDLAGF--AD--RFVDQISGGQQQRVALARALILKPKVLLFD 161
Cdd:TIGR03719 396 --ALDPNKTVWEEISGGLDIIKLGKREIPSRA-----YVGRFNFkgSDqqKKVGQLSGGERNRVHLAKTLKSGGNVLLLD 468

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 757596975  162 EPLSNLDANLRRSMREKIRElqqqFNITSLYVTHD 196
Cdd:TIGR03719 469 EPTNDLDVETLRALEEALLN----FAGCAVVISHD 499
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 17-219 3.81e-24

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 103.20  E-value: 3.81e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   17 GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT--DRSIQQRDICMVFQSYALFPHmS 94
Cdd:TIGR01842 329 GKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKqwDRETFGKHIGYLPQDVELFPG-T 407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   95 LGDNVGyglKMLGLPKAEirkRVDEALELVD----LAGFADRFVDQI-------SGGQQQRVALARALILKPKVLLFDEP 163
Cdd:TIGR01842 408 VAENIA---RFGENADPE---KIIEAAKLAGvhelILRLPDGYDTVIgpggatlSGGQRQRIALARALYGDPKLVVLDEP 481

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975  164 LSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSeAFAVSDMVLVMNKGKIMQLG 219
Cdd:TIGR01842 482 NSNLDEEGEQALANAIKALKAR-GITVVVITHRPS-LLGCVDKILVLQDGRIARFG 535
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 7-219 3.93e-24

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 97.00  E-value: 3.93e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN--TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRD-ICMV 83
Cdd:cd03247    1 LSINNVSFSYPEQeqQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKALSSlISVL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSYALFpHMSLGDNVGyglkmlglpkaeirkrvdealelvdlagfadrfvDQISGGQQQRVALARALILKPKVLLFDEP 163
Cdd:cd03247   81 NQRPYLF-DTTLRNNLG----------------------------------RRFSGGERQRLALARILLQDAPIVLLDEP 125

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 164 LSNLDANLRRSMREKIreLQQQFNITSLYVTHDQSeAFAVSDMVLVMNKGKIMQLG 219
Cdd:cd03247  126 TVGLDPITERQLLSLI--FEVLKDKTLIWITHHLT-GIEHMDKILFLENGKIIMQG 178
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 8-170 4.56e-24

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 97.64  E-value: 4.56e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRS-------IQQRDi 80
Cdd:PRK13539   4 EGEDLACVRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDvaeachyLGHRN- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 cmvfqsyALFPHMSLGDNVGYGLKMLGLPKAEIrkrvDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:PRK13539  83 -------AMKPALTVAENLEFWAAFLGGEELDI----AAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWIL 151

                        170
                 ....*....|
gi 757596975 161 DEPLSNLDAN 170
Cdd:PRK13539 152 DEPTAALDAA 161
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
7-227 7.83e-24

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 102.40  E-value: 7.83e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF-GTNT-VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QRDICM 82
Cdd:PRK11176 342 IEFRNVTFTYpGKEVpALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTLAslRNQVAL 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFpHMSLGDNVGYGLKmlglpKAEIRKRVDEALELVDLAGFADRF---VDQI--------SGGQQQRVALARAL 151
Cdd:PRK11176 422 VSQNVHLF-NDTIANNIAYART-----EQYSREQIEEAARMAYAMDFINKMdngLDTVigengvllSGGQRQRIAIARAL 495

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSeAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:PRK11176 496 LRDSPILILDEATSALDTESERAIQAALDELQK--NRTSLVIAHRLS-TIEKADEILVVEDGEIVERGTHAELLAQ 568
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 7-214 8.88e-24

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 101.83  E-value: 8.88e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGL--EKPTEGRMFIDGEDVTDRSI---QQRDIC 81
Cdd:TIGR02633   2 LEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVypHGTWDGEIYWSGSPLKASNIrdtERAGIV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   82 MVFQSYALFPHMSLGDNVGYG----LKMLGLPKAEIRKRVDEALELVDLAGFAD-RFVDQISGGQQQRVALARALILKPK 156
Cdd:TIGR02633  82 IIHQELTLVPELSVAENIFLGneitLPGGRMAYNAMYLRAKNLLRELQLDADNVtRPVGDYGGGQQQLVEIAKALNKQAR 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975  157 VLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGK 214
Cdd:TIGR02633 162 LLILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQ 218
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 8-227 9.40e-24

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 96.83  E-value: 9.40e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLE--KPTEGRMFIDGEDVTDRSIQQR---DICM 82
Cdd:cd03217    2 EIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEILFKGEDITDLPPEERarlGIFL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFPHMSLGDNVGYglkmlglpkaeirkrVDEalelvdlaGFadrfvdqiSGGQQQRVALARALILKPKVLLFDE 162
Cdd:cd03217   82 AFQYPPEIPGVKNADFLRY---------------VNE--------GF--------SGGEKKRNEILQLLLLEPDLAILDE 130

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 163 PLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEA-FAVSDMVLVMNKGKIMQLGsPQELYRQ 227
Cdd:cd03217  131 PDSGLDIDALRLVAEVINKLREE-GKSVLIITHYQRLLdYIKPDRVHVLYDGRIVKSG-DKELALE 194
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
6-170 1.08e-23

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 96.80  E-value: 1.08e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   6 FVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTdrsiQQRDicmVFQ 85
Cdd:PRK13538   1 MLEARNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIR----RQRD---EYH 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALF--------PHMSLGDNVGYGLKMLGLPKAEirkRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKV 157
Cdd:PRK13538  74 QDLLYlghqpgikTELTALENLRFYQRLHGPGDDE---ALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPL 150

                        170
                 ....*....|...
gi 757596975 158 LLFDEPLSNLDAN 170
Cdd:PRK13538 151 WILDEPFTAIDKQ 163
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 7-224 1.38e-23

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 101.44  E-value: 1.38e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF--GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ-RD-ICM 82
Cdd:PRK11160 339 LTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAAlRQaISV 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFPHmSLGDNVgyglkMLGLPKAeIRKRVDEALELVDLAGFAD-------------RfvdQISGGQQQRVALAR 149
Cdd:PRK11160 419 VSQRVHLFSA-TLRDNL-----LLAAPNA-SDEALIEVLQQVGLEKLLEddkglnawlgeggR---QLSGGEQRRLGIAR 488

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 150 ALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHdQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:PRK11160 489 ALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQ--NKTVLMITH-RLTGLEQFDRICVMDNGQIIEQGTHQEL 560
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 8-213 1.53e-23

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 96.73  E-value: 1.53e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRF------GTN-TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFID-GEDVTD------R 73
Cdd:COG4778    6 EVENLSKTFtlhlqgGKRlPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRhDGGWVDlaqaspR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  74 SI---QQRDICMVFQsyalF----PHMSLGDNVGYGLKMLGLPKAEIRKRVDEAL-------ELVDL--AGFadrfvdqi 137
Cdd:COG4778   86 EIlalRRRTIGYVSQ----FlrviPRVSALDVVAEPLLERGVDREEARARARELLarlnlpeRLWDLppATF-------- 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 138 SGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKG 213
Cdd:COG4778  154 SGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRVVDVTPF 228
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 8-229 1.71e-23

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 99.03  E-value: 1.71e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKT-TVLRLVAGLEKP--TEGRMFIDGEDVTD------RS 74
Cdd:PRK09473  14 DVKDLRVTFSTPdgdvTAVNDLNFSLRAGETLGIVGESGSGKSqTAFALMGLLAANgrIGGSATFNGREILNlpekelNK 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  75 IQQRDICMVFQS--YALFPHMSLGDNVGYGLkML--GLPKAEIRKRVDEALELVDLAGFADR---FVDQISGGQQQRVAL 147
Cdd:PRK09473  94 LRAEQISMIFQDpmTSLNPYMRVGEQLMEVL-MLhkGMSKAEAFEESVRMLDAVKMPEARKRmkmYPHEFSGGMRQRVMI 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 148 ARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:PRK09473 173 AMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQ 252


                 ..
gi 757596975 228 PA 229
Cdd:PRK09473 253 PS 254
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
6-214 2.54e-23

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 100.37  E-value: 2.54e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   6 FVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIqqRD-----I 80
Cdd:PRK11288   4 YLSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFAST--TAalaagV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 CMVFQSYALFPHMSLGDNVgyglkMLG-LP-------KAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALI 152
Cdd:PRK11288  82 AIIYQELHLVPEMTVAENL-----YLGqLPhkggivnRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALA 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 153 LKPKVLLFDEPLSNLdanlrrSMREK------IRELQQQFNITsLYVTHDQSEAFAVSDMVLVMNKGK 214
Cdd:PRK11288 157 RNARVIAFDEPTSSL------SAREIeqlfrvIRELRAEGRVI-LYVSHRMEEIFALCDAITVFKDGR 217
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
12-219 5.85e-23

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 96.49  E-value: 5.85e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  12 VTKRFGtNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDvTDRSIQQRDICMVFQSYAL-- 89
Cdd:PRK15056  14 VTWRNG-HTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQP-TRQALQKNLVAYVPQSEEVdw 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  90 -FPHMsLGDNVGYG----LKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPL 164
Cdd:PRK15056  92 sFPVL-VEDVVMMGryghMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPF 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 165 SNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVlVMNKGKIMQLG 219
Cdd:PRK15056 171 TGVDVKTEARIISLLRELRDE-GKTMLVSTHNLGSVTEFCDYT-VMVKGTVLASG 223
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
7-216 7.85e-23

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 95.33  E-value: 7.85e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTD---RSIQQRDICMV 83
Cdd:PRK11614   6 LSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDwqtAKIMREAVAIV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSYALFPHMSLGDNvgygLKMLGL--PKAEIRKRVDEALELvdLAGFADRFVDQ---ISGGQQQRVALARALILKPKVL 158
Cdd:PRK11614  86 PEGRRVFSRMTVEEN----LAMGGFfaERDQFQERIKWVYEL--FPRLHERRIQRagtMSGGEQQMLAIGRALMSQPRLL 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 159 LFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIM 216
Cdd:PRK11614 160 LLDEPSLGLAPIIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHVV 216
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 18-229 1.42e-22

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 98.24  E-value: 1.42e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  18 TNTVIDDLSLSIPQGSMVTLLGPSGCGKT----TVLRLvagLEKP----TEGRMFIDGEDV------TDRSIQQRDICMV 83
Cdd:PRK15134  21 VRTVVNDVSLQIEAGETLALVGESGSGKSvtalSILRL---LPSPpvvyPSGDIRFHGESLlhaseqTLRGVRGNKIAMI 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSyalfPHMSLgdNVGYGL-KML--------GLPKAEIRKRVDEALELVDLAGFADRFVD---QISGGQQQRVALARAL 151
Cdd:PRK15134  98 FQE----PMVSL--NPLHTLeKQLyevlslhrGMRREAARGEILNCLDRVGIRQAAKRLTDyphQLSGGERQRVMIAMAL 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPA 229
Cdd:PRK15134 172 LTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSAPT 249
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 22-228 1.72e-22

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 95.96  E-value: 1.72e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGL----EKPTEGRMFIDGEDVTDRSIQQR------DICMVFQS--YAL 89
Cdd:PRK11022  23 VDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLidypGRVMAEKLEFNGQDLQRISEKERrnlvgaEVAMIFQDpmTSL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  90 FPHMSLGDNVGYGLKM-LGLPKAEIRKRVDEALELV---DLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
Cdd:PRK11022 103 NPCYTVGFQIMEAIKVhQGGNKKTRRQRAIDLLNQVgipDPASRLDVYPHQLSGGMSQRVMIAMAIACRPKLLIADEPTT 182

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK11022 183 ALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRAP 245
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 22-274 3.01e-22

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 97.62  E-value: 3.01e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKT----TVLRLV--AGLEKPTEG-------RMFIDGEDVTD---RSIQQRDICMVFQ 85
Cdd:PRK10261  32 VRNLSFSLQRGETLAIVGESGSGKSvtalALMRLLeqAGGLVQCDKmllrrrsRQVIELSEQSAaqmRHVRGADMAMIFQ 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 S--YALFPHMSLGDNVGYGLKM-LGLPKAEIRKRVDEALELV---DLAGFADRFVDQISGGQQQRVALARALILKPKVLL 159
Cdd:PRK10261 112 EpmTSLNPVFTVGEQIAESIRLhQGASREEAMVEAKRMLDQVripEAQTILSRYPHQLSGGMRQRVMIAMALSCRPAVLI 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 160 FDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMASFMGD 239
Cdd:PRK10261 192 ADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAPQHPYTRALLAA 271

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 757596975 240 ANIFPATLTHDSVNIFNY-HLPRPAQLATDNTEITV 274
Cdd:PRK10261 272 VPQLGAMKGLDYPRRFPLiSLEHPAKQEPPIEQDTV 307
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 8-216 3.27e-22

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 97.02  E-value: 3.27e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVT-KRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVF-- 84
Cdd:COG3845  259 EVENLSvRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRERRRLGVAyi 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 ----QSYALFPHMSLGDNV---GYGLKMLG----LPKAEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARALI 152
Cdd:COG3845  339 pedrLGRGLVPDMSVAENLilgRYRRPPFSrggfLDRKAIRAFAEELIEEFDVrTPGPDTPARSLSGGNQQKVILARELS 418

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757596975 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIM 216
Cdd:COG3845  419 RDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDA-GAAVLLISEDLDEILALSDRIAVMYEGRIV 481
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 10-227 3.73e-22

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 93.84  E-value: 3.73e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  10 KNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSI------QQR----- 78
Cdd:PRK11701  10 RGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDLyalseaERRrllrt 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 DICMVFQSYA--LFPHMSLGDNVGYGLKMLGLPK-AEIRKRVDEALELVDLAgfADRFVDQ---ISGGQQQRVALARALI 152
Cdd:PRK11701  90 EWGFVHQHPRdgLRMQVSAGGNIGERLMAVGARHyGDIRATAGDWLERVEID--AARIDDLpttFSGGMQQRLQIARNLV 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG-------SPQELY 225
Cdd:PRK11701 168 THPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESGltdqvldDPQHPY 247


                 ..
gi 757596975 226 RQ 227
Cdd:PRK11701 248 TQ 249
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 7-214 2.76e-21

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 90.22  E-value: 2.76e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVT-----KRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEdvtdrsiqqrdIC 81
Cdd:cd03250    1 ISVEDASftwdsGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS-----------IA 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSYALFPhMSLGDNVGYGLKMlglpkaeIRKRVDEALE----LVDLAGFADRfvDQ---------ISGGQQQRVALA 148
Cdd:cd03250   70 YVSQEPWIQN-GTIRENILFGKPF-------DEERYEKVIKacalEPDLEILPDG--DLteigekginLSGGQKQRISLA 139

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 149 RALILKPKVLLFDEPLSNLDANLRRSMREK-IRELQQQfNITSLYVTHdQSEAFAVSDMVLVMNKGK 214
Cdd:cd03250  140 RAVYSDADIYLLDDPLSAVDAHVGRHIFENcILGLLLN-NKTRILVTH-QLQLLPHADQIVVLDNGR 204
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 7-177 5.19e-21

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 94.03  E-value: 5.19e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIdGEDVT----DrsiQQRDicm 82
Cdd:PRK11819 325 IEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETVKlayvD---QSRD--- 397

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 vfqsyALFPHMSLGDNVGYGLKMLGLPKAEIRKRvdealelvdlaGFADRF----------VDQISGGQQQRVALARALI 152
Cdd:PRK11819 398 -----ALDPNKTVWEEISGGLDIIKVGNREIPSR-----------AYVGRFnfkggdqqkkVGVLSGGERNRLHLAKTLK 461

                        170       180
                 ....*....|....*....|....*
gi 757596975 153 LKPKVLLFDEPLSNLDANLRRSMRE 177
Cdd:PRK11819 462 QGGNVLLLDEPTNDLDVETLRALEE 486
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 21-185 6.21e-21

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 89.24  E-value: 6.21e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  21 VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDV-TDRSIQQRDICMVFQSYALFPHMSLGDNV 99
Cdd:PRK13540  16 LLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIkKDLCTYQKQLCFVGHRSGINPYLTLRENC 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 100 GYGLKMlglpkAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKI 179
Cdd:PRK13540  96 LYDIHF-----SPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITKI 170


                 ....*.
gi 757596975 180 RELQQQ 185
Cdd:PRK13540 171 QEHRAK 176
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 7-221 6.61e-21

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 89.48  E-value: 6.61e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF--GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTV----LRLVagleKPTEGRMFIDGEDVTDRSIQQ--R 78
Cdd:cd03244    3 IEFKNVSLRYrpNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLllalFRLV----ELSSGSILIDGVDISKIGLHDlrS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 DICMVFQSYALFPhmslgdnvgyglkmlglpkAEIRKRVD-----------EALELVDLAGFADRFVDQI---------- 137
Cdd:cd03244   79 RISIIPQDPVLFS-------------------GTIRSNLDpfgeysdeelwQALERVGLKEFVESLPGGLdtvveeggen 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 138 -SGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRElqqQF-NITSLYVTHdQSEAFAVSDMVLVMNKGKI 215
Cdd:cd03244  140 lSVGQRQLLCLARALLRKSKILVLDEATASVDPETDALIQKTIRE---AFkDCTVLTIAH-RLDTIIDSDRILVLDKGRV 215


                 ....*.
gi 757596975 216 MQLGSP 221
Cdd:cd03244  216 VEFDSP 221
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 8-217 1.13e-20

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 88.86  E-value: 1.13e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDgedVTDRSIQQRdicmvfqsy 87
Cdd:COG2401   32 EAFGVELRVVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTPVAGCVD---VPDNQFGRE--------- 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  88 alfphMSLGDNVGyglkmlglpkaeIRKRVDEALELVDLAGFAD-----RFVDQISGGQQQRVALARALILKPKVLLFDE 162
Cdd:COG2401  100 -----ASLIDAIG------------RKGDFKDAVELLNAVGLSDavlwlRRFKELSTGQKFRFRLALLLAERPKLLVIDE 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 163 PLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQS-EAFAVSDMVLVMNKGKIMQ 217
Cdd:COG2401  163 FCSHLDRQTAKRVARNLQKLARRAGITLVVATHHYDvIDDLQPDLLIFVGYGGVPE 218
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
7-224 1.73e-20

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 92.47  E-value: 1.73e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGT-NTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QRDICMV 83
Cdd:PRK10790 341 IDIDNVSFAYRDdNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSvlRQGVAMV 420

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSYALFPHmSLGDNVgyglkMLGLPKAEirKRVDEALELVDLAGFADRFVDQI-----------SGGQQQRVALARALI 152
Cdd:PRK10790 421 QQDPVVLAD-TFLANV-----TLGRDISE--EQVWQALETVQLAELARSLPDGLytplgeqgnnlSVGQKQLLALARVLV 492

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfniTSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:PRK10790 493 QTPQILILDEATANIDSGTEQAIQQALAAVREH---TTLVVIAHRLSTIVEADTILVLHRGQAVEQGTHQQL 561
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 3-224 1.78e-20

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 92.42  E-value: 1.78e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    3 QHNFVELKNVTKRfGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVL-----RLVAGLEKptEGRMFIDGEDVTDRSIQQ 77
Cdd:TIGR00955  23 LVSRLRGCFCRER-PRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMnalafRSPKGVKG--SGSVLLNGMPIDAKEMRA 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   78 RDiCMVFQSYALFPHMSLGDNVGYG--LKM-LGLPKAEIRKRVDEALELVDLAGFAD------RFVDQISGGQQQRVALA 148
Cdd:TIGR00955 100 IS-AYVQQDDLFIPTLTVREHLMFQahLRMpRRVTKKEKRERVDEVLQALGLRKCANtrigvpGRVKGLSGGERKRLAFA 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975  149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:TIGR00955 179 SELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILMAEGRVAYLGSPDQA 254
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 7-221 2.29e-20

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 92.77  E-value: 2.29e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975     7 VELKNVTKRFGT--NTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDV-TDRSIQQRDICMV 83
Cdd:TIGR01257  929 VCVKNLVKIFEPsgRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIeTNLDAVRQSLGMC 1008

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    84 FQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEP 163
Cdd:TIGR01257 1009 PQHNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEP 1088

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975   164 LSNLDANLRRSMREKIreLQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSP 221
Cdd:TIGR01257 1089 TSGVDPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTP 1144
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
6-233 2.66e-20

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 91.77  E-value: 2.66e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   6 FVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGED---VTDRSIQQRDICM 82
Cdd:PRK09700   5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINynkLDHKLAAQLGIGI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFPHMSLGDNVGYGL----KMLGLPK---AEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKP 155
Cdd:PRK09700  85 IYQELSVIDELTVLENLYIGRhltkKVCGVNIidwREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDA 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 156 KVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFM 233
Cdd:PRK09700 165 KVIIMDEPTSSLTNKEVDYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDVSNDDIVRLM 241
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 7-212 6.77e-20

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 85.28  E-value: 6.77e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTV-IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGL--------EKPTEGRMFIdgedvtdrsIQQ 77
Cdd:cd03223    1 IELENLSLATPDGRVlLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLwpwgsgriGMPEGEDLLF---------LPQ 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  78 RdicmvfqSYalFPHMSLGDNVGYGLKmlglpkaeirkrvdealelvdlagfadrfvDQISGGQQQRVALARALILKPKV 157
Cdd:cd03223   72 R-------PY--LPLGTLREQLIYPWD------------------------------DVLSGGEQQRLAFARLLLHKPKF 112

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 158 LLFDEPLSNLDANLRRSMREKIRELQqqfnITSLYVTHDQS-EAFAvsDMVLVMNK 212
Cdd:cd03223  113 VFLDEATSALDEESEDRLYQLLKELG----ITVISVGHRPSlWKFH--DRVLDLDG 162
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 3-221 1.24e-19

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 85.54  E-value: 1.24e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   3 QHNFVELKNVTKRFGTN--TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QR 78
Cdd:cd03369    3 EHGEIEVENLSVRYAPDlpPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEdlRS 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 DICMVFQSYALFphmslgdnvgyglkmlglpKAEIRKRVDEALELVDLAGFADRFV----DQISGGQQQRVALARALILK 154
Cdd:cd03369   83 SLTIIPQDPTLF-------------------SGTIRSNLDPFDEYSDEEIYGALRVseggLNLSQGQRQLLCLARALLKR 143

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 155 PKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHdQSEAFAVSDMVLVMNKGKIMQLGSP 221
Cdd:cd03369  144 PRVLVLDEATASIDYATDALIQKTIREEFT--NSTILTIAH-RLRTIIDYDKILVMDAGEVKEYDHP 207
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 8-215 1.55e-19

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 89.22  E-value: 1.55e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNT---VIDDLSLSIPQGSMVTLLGPSGCGKT-TVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ---RDI 80
Cdd:PRK13549 261 EVRNLTAWDPVNPhikRVDDVSFSLRRGEILGIAGLVGAGRTeLVQCLFGAYPGRWEGEIFIDGKPVKIRNPQQaiaQGI 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  81 CMVFQS---YALFPHMSLGDNVgyglKMLGLPKAEIRKRVDEALELVDLAGFADRF----------VDQISGGQQQRVAL 147
Cdd:PRK13549 341 AMVPEDrkrDGIVPVMGVGKNI----TLAALDRFTGGSRIDDAAELKTILESIQRLkvktaspelaIARLSGGNQQKAVL 416

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 148 ARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:PRK13549 417 AKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQ-GVAIIVISSELPEVLGLSDRVLVMHEGKL 483
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 24-215 1.72e-19

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 89.34  E-value: 1.72e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  24 DLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQR-DICMVF-----QSYALFPHMSLGD 97
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQRlARGLVYlpedrQSSGLYLDAPLAW 360

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  98 NV-GYGLKMLGL---PKAE--IRKRVDEALElVDLAGfADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANL 171
Cdd:PRK15439 361 NVcALTHNRRGFwikPAREnaVLERYRRALN-IKFNH-AEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSA 438

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 757596975 172 RRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:PRK15439 439 RNDIYQLIRSIAAQ-NVAVLFISSDLEEIEQMADRVLVMHQGEI 481
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 10-210 1.93e-19

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 86.27  E-value: 1.93e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  10 KNVTKRFGTNTvIDDLSLSIPQGSMVT-LLGPSGCGKTTVLRLVAGLEKPTEGRMfiDGEDVTDrsiqqrDICMVFQSYA 88
Cdd:cd03236    4 DEPVHRYGPNS-FKLHRLPVPREGQVLgLVGPNGIGKSTALKILAGKLKPNLGKF--DDPPDWD------EILDEFRGSE 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  89 L---FPHMsLGDNVGYGLK---MLGLPKA------EIRKRVDE--ALELV----DLAGFADRFVDQISGGQQQRVALARA 150
Cdd:cd03236   75 LqnyFTKL-LEGDVKVIVKpqyVDLIPKAvkgkvgELLKKKDErgKLDELvdqlELRHVLDRNIDQLSGGELQRVAIAAA 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 151 LILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITsLYVTHDQSEAFAVSDMVLVM 210
Cdd:cd03236  154 LARDADFYFFDEPSSYLDIKQRLNAARLIRELAEDDNYV-LVVEHDLAVLDYLSDYIHCL 212
hmuV PRK13547
heme ABC transporter ATP-binding protein;
19-229 1.96e-19

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 86.80  E-value: 1.96e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  19 NTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAG-LEKPTE-------GRMFIDGED---VTDRSIQQRDICMVFQSY 87
Cdd:PRK13547  14 RAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGdLTGGGAprgarvtGDVTLNGEPlaaIDAPRLARLRAVLPQAAQ 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  88 ALFPhMSLGDNVGYG----LKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARAL---------ILK 154
Cdd:PRK13547  94 PAFA-FSAREIVLLGryphARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLaqlwpphdaAQP 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 155 PKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRqPA 229
Cdd:PRK13547 173 PRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADVLT-PA 246
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 11-227 2.86e-19

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 85.65  E-value: 2.86e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   11 NVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ-----------RD 79
Cdd:TIGR02323   8 GLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRSGAELELYQlseaerrrlmrTE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   80 ICMVFQSYA--LFPHMSLGDNVGYGLKMLGLPK-AEIRKRVDEALELVDL-AGFADRFVDQISGGQQQRVALARALILKP 155
Cdd:TIGR02323  88 WGFVHQNPRdgLRMRVSAGANIGERLMAIGARHyGNIRATAQDWLEEVEIdPTRIDDLPRAFSGGMQQRLQIARNLVTRP 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975  156 KVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG-------SPQELYRQ 227
Cdd:TIGR02323 168 RLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESGltdqvldDPQHPYTQ 246
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 22-231 4.43e-19

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 85.14  E-value: 4.43e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKP----TEGRMFIDGEDVTDRSIQQRDICMVFQS--YALFPHMSL 95
Cdd:PRK10418  19 VHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAgvrqTAGRVLLDGKPVAPCALRGRKIATIMQNprSAFNPLHTM 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  96 GDNVGYGLKMLGLPKAEirKRVDEALELVDLAG---FADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLR 172
Cdd:PRK10418  99 HTHARETCLALGKPADD--ATLTAALEAVGLENaarVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLDVVAQ 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975 173 RSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASR 231
Cdd:PRK10418 177 ARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHA 235
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 8-215 4.64e-19

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 87.96  E-value: 4.64e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    8 ELKNVTKRFGTNTVI---DDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGL-EKPTEGRMFIDGEDVTDRSIQQ---RDI 80
Cdd:TIGR02633 259 EARNLTCWDVINPHRkrvDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAyPGKFEGNVFINGKPVDIRNPAQairAGI 338

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   81 CMVFQS---YALFPHMSLGDNVgyglKMLGLPKAEIRKRVDEALELVDLAGFADRF----------VDQISGGQQQRVAL 147
Cdd:TIGR02633 339 AMVPEDrkrHGIVPILGVGKNI----TLSVLKSFCFKMRIDAAAELQIIGSAIQRLkvktaspflpIGRLSGGNQQKAVL 414

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975  148 ARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:TIGR02633 415 AKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQE-GVAIIVVSSELAEVLGLSDRVLVIGEGKL 481
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
21-168 7.91e-19

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 83.74  E-value: 7.91e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  21 VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTdRSIQQRDICMVFQSYALFPHMSLGDNVG 100
Cdd:PRK13543  26 VFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTAT-RGDRSRFMAYLGHLPGLKADLSTLENLH 104

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975 101 YglkMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARaLILKPKVL-LFDEPLSNLD 168
Cdd:PRK13543 105 F---LCGLHGRRAKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALAR-LWLSPAPLwLLDEPYANLD 169
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 5-215 1.02e-18

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 83.08  E-value: 1.02e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   5 NFVELKNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPT---EGRMFIDGEDVTD-RSIQ 76
Cdd:cd03233    2 STLSWRNISFTTGKGrskiPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEfAEKY 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  77 QRDICMVFQSYALFPHMSLGDNVGYGLKMLGlpkaeirkrvdealelvdlagfaDRFVDQISGGQQQRVALARALILKPK 156
Cdd:cd03233   82 PGEIIYVSEEDVHFPTLTVRETLDFALRCKG-----------------------NEFVRGISGGERKRVSIAEALVSRAS 138

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 157 VLLFDEPLSNLDANLRRSMREKIRELQQQFNIT---SLYVTHDqsEAFAVSDMVLVMNKGKI 215
Cdd:cd03233  139 VLCWDNSTRGLDSSTALEILKCIRTMADVLKTTtfvSLYQASD--EIYDLFDKVLVLYEGRQ 198
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 22-237 1.77e-18

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 86.92  E-value: 1.77e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLR-LVAGLEKpTEGRMFIDGEdvtdrsiqqrdICMVFQSyALFPHMSLGDNVg 100
Cdd:TIGR00957  654 LNGITFSIPEGALVAVVGQVGCGKSSLLSaLLAEMDK-VEGHVHMKGS-----------VAYVPQQ-AWIQNDSLRENI- 719

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   101 yglkMLGLPKAEIR-KRVDEALELV---------DLAGFADRFVDqISGGQQQRVALARALILKPKVLLFDEPLSNLDAN 170
Cdd:TIGR00957  720 ----LFGKALNEKYyQQVLEACALLpdleilpsgDRTEIGEKGVN-LSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAH 794

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975   171 LRRSMREKIRELQQQF-NITSLYVTHDQSEAFAVsDMVLVMNKGKIMQLGSPQELYRQPASrfMASFM 237
Cdd:TIGR00957  795 VGKHIFEHVIGPEGVLkNKTRILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQRDGA--FAEFL 859
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 25-223 6.73e-18

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 81.81  E-value: 6.73e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  25 LSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEkPTEGRMFIDGEDVTDRSIQQ--RDICM------------VFQSYALf 90
Cdd:COG4138   15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLNGRPLSDWSAAElaRHRAYlsqqqsppfampVFQYLAL- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  91 pHMSLGdnvgyglkmlgLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALI-------LKPKVLLFDEP 163
Cdd:COG4138   93 -HQPAG-----------ASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLqvwptinPEGQLLLLDEP 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 164 LSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQE 223
Cdd:COG4138  161 MNSLDVAQQAALDRLLRELCQQ-GITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAE 219
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 7-218 7.19e-18

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 84.64  E-value: 7.19e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTV-IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QRDICMV 83
Cdd:PRK10522 323 LELRNVTFAYQDNGFsVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEdyRKLFSAV 402

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSYALFPHMsLGDNvgyglkmlGLPKAEirKRVD---EALELVDLAGFAD-RFVD-QISGGQQQRVALARALILKPKVL 158
Cdd:PRK10522 403 FTDFHLFDQL-LGPE--------GKPANP--ALVEkwlERLKMAHKLELEDgRISNlKLSKGQKKRLALLLALAEERDIL 471

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 159 LFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSeAFAVSDMVLVMNKGKIMQL 218
Cdd:PRK10522 472 LLDEWAADQDPHFRREFYQVLLPLLQEMGKTIFAISHDDH-YFIHADRLLEMRNGQLSEL 530
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 25-215 1.46e-17

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 83.69  E-value: 1.46e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  25 LSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ-RD-ICMVFQSYALFPHmslgdnvgyg 102
Cdd:COG4615  351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTADNREAyRQlFSAVFSDFHLFDR---------- 420

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 103 lkMLGLPKAEIRKRVDEALELVDLAG---FAD-RFVD-QISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSM-R 176
Cdd:COG4615  421 --LLGLDGEADPARARELLERLELDHkvsVEDgRFSTtDLSQGQRKRLALLVALLEDRPILVFDEWAADQDPEFRRVFyT 498

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 757596975 177 EKIRELQQQfNITSLYVTHDQSeAFAVSDMVLVMNKGKI 215
Cdd:COG4615  499 ELLPELKAR-GKTVIAISHDDR-YFDLADRVLKMDYGKL 535
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 7-224 2.47e-17

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 82.79  E-value: 2.47e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRS---IQQRDICMV 83
Cdd:PRK15439  12 LCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTpakAHQLGIYLV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  84 FQSYALFPHMSLGDNVgyglkMLGLPKAEIRKRVDEAL--EL---VDL---AG---FADrfvdqisggqQQRVALARALI 152
Cdd:PRK15439  92 PQEPLLFPNLSVKENI-----LFGLPKRQASMQKMKQLlaALgcqLDLdssAGsleVAD----------RQIVEILRGLM 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:PRK15439 157 RDSRILILDEPTASLTPAETERLFSRIRELLAQ-GVGIVFISHKLPEIRQLADRISVMRDGTIALSGKTADL 227
GguA NF040905
sugar ABC transporter ATP-binding protein;
8-214 2.52e-17

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 82.53  E-value: 2.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLeKPT---EGRMFIDGEDVTDRSI---QQRDIC 81
Cdd:NF040905   3 EMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGV-YPHgsyEGEILFDGEVCRFKDIrdsEALGIV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSYALFPHMSLGDNVgyglkMLGLPKA--------EIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALIL 153
Cdd:NF040905  82 IIHQELALIPYLSIAENI-----FLGNERAkrgvidwnETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSK 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 154 KPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGK 214
Cdd:NF040905 157 DVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGR 216
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 9-196 3.13e-17

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 82.68  E-value: 3.13e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    9 LKNVTKRFGTN-TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPtegrmfIDGEDVTDRSIQqrdICMVFQSY 87
Cdd:TIGR03719   7 MNRVSKVVPPKkEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKD------FNGEARPQPGIK---VGYLPQEP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   88 ALFPHMSLGDNVGYGLK--------------MLGLPKAEIRKRVDEALEL---------------VDLAGFA------DR 132
Cdd:TIGR03719  78 QLDPTKTVRENVEEGVAeikdaldrfneisaKYAEPDADFDKLAAEQAELqeiidaadawdldsqLEIAMDAlrcppwDA 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975  133 FVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDAnlrrsmrEKIRELQQ---QFNITSLYVTHD 196
Cdd:TIGR03719 158 DVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDA-------ESVAWLERhlqEYPGTVVAVTHD 217
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 21-198 3.29e-17

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 82.49  E-value: 3.29e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   21 VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGL--------EKPTEGRMFIdgedvtdrsIQQRdicmvfqsyalfPH 92
Cdd:TIGR00954 467 LIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELwpvyggrlTKPAKGKLFY---------VPQR------------PY 525

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   93 MSLG---DNVGY-----GLKMLGLPKAEIRKrvdeALELVDLAGFADR---------FVDQISGGQQQRVALARALILKP 155
Cdd:TIGR00954 526 MTLGtlrDQIIYpdsseDMKRRGLSDKDLEQ----ILDNVQLTHILEReggwsavqdWMDVLSGGEKQRIAMARLFYHKP 601

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 757596975  156 KVLLFDEPLSNLDANlrrsMREKIRELQQQFNITSLYVTHDQS 198
Cdd:TIGR00954 602 QFAILDECTSAVSVD----VEGYMYRLCREFGITLFSVSHRKS 640
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 23-235 3.75e-17

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 79.76  E-value: 3.75e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  23 DDLSLSIPQGS-----MVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVtdrSIQQRDICMVFQS--YALFphMSL 95
Cdd:cd03237   11 GEFTLEVEGGSiseseVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTV---SYKPQYIKADYEGtvRDLL--SSI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  96 GDNVGYGLKMlglpKAEIRKrvdeALELVDLAgfaDRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSM 175
Cdd:cd03237   86 TKDFYTHPYF----KTEIAK----PLQIEQIL---DREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMA 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 176 REKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMN--KGKIMQLGSPQELyRQPASRFMAS 235
Cdd:cd03237  155 SKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIVFEgePSVNGVANPPQSL-RSGMNRFLKN 215
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 5-224 3.95e-17

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 82.75  E-value: 3.95e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975     5 NFVELKNVTKRF-GTNT-VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDrsiqqrDICM 82
Cdd:TIGR01257 1936 DILRLNELTKVYsGTSSpAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILT------NISD 2009

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    83 VFQSYALFPHMSLGDNVGYGLKML-------GLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKP 155
Cdd:TIGR01257 2010 VHQNMGYCPQFDAIDDLLTGREHLylyarlrGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCP 2089

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975   156 KVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLyVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:TIGR01257 2090 PLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVL-TSHSMEECEALCTRLAIMVKGAFQCLGTIQHL 2157
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 8-207 7.79e-17

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 81.37  E-value: 7.79e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 EL-KNVTKRFGTNTVidDL-SLSIPQGSMVT-LLGPSGCGKTTVLRLVAGLEKPTEGRmfIDGEDVTDRSIQQrdicmvF 84
Cdd:COG1245   74 ELeEDPVHRYGENGF--RLyGLPVPKKGKVTgILGPNGIGKSTALKILSGELKPNLGD--YDEEPSWDEVLKR------F 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMS-LGDN----------VGYGLKMLG------LPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVAL 147
Cdd:COG1245  144 RGTELQDYFKkLANGeikvahkpqyVDLIPKVFKgtvrelLEKVDERGKLDELAEKLGLENILDRDISELSGGELQRVAI 223

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 148 ARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDqseaFAVSDMV 207
Cdd:COG1245  224 AAALLRDADFYFFDEPSSYLDIYQRLNVARLIRELAEE-GKYVLVVEHD----LAILDYL 278
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 1-220 9.07e-17

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 78.53  E-value: 9.07e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   1 MTQHNFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLE--KPTEGRMFIDGEDVTDRSIQQR 78
Cdd:CHL00131   2 NKNKPILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPayKILEGDILFKGESILDLEPEER 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 D---ICMVFQSYALFPHMSLGD--NVGYG--LKMLGLPKA---EIRKRVDEALELVDL-AGFADRFVDQ-ISGGQQQRVA 146
Cdd:CHL00131  82 AhlgIFLAFQYPIEIPGVSNADflRLAYNskRKFQGLPELdplEFLEIINEKLKLVGMdPSFLSRNVNEgFSGGEKKRNE 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 147 LARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNiTSLYVTHDQS-EAFAVSDMVLVMNKGKIMQLGS 220
Cdd:CHL00131 162 ILQMALLDSELAILDETDSGLDIDALKIIAEGINKLMTSEN-SIILITHYQRlLDYIKPDYVHVMQNGKIIKTGD 235
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
8-218 1.98e-16

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 80.21  E-value: 1.98e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRfgTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRS---IQQRDICMVF 84
Cdd:PRK09700 267 EVRNVTSR--DRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSpldAVKKGMAYIT 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSY---ALFPHMSLGDNV---------GYGLKMLGLPKAEIRKRVDEALELVDLAGFA-DRFVDQISGGQQQRVALARAL 151
Cdd:PRK09700 345 ESRrdnGFFPNFSIAQNMaisrslkdgGYKGAMGLFHEVDEQRTAENQRELLALKCHSvNQNITELSGGNQQKVLISKWL 424

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQL 218
Cdd:PRK09700 425 CCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADD-GKVILMVSSELPEIITVCDRIAVFCEGRLTQI 490
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 25-228 4.14e-16

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 76.90  E-value: 4.14e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  25 LSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLeKPTEGRMFIDGEDVTDRSI------------QQRD-ICM-VFQSYALf 90
Cdd:PRK03695  15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPLEAWSAaelarhraylsqQQTPpFAMpVFQYLTL- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  91 phmSLGDnvgyglkmlGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALI-----LKP--KVLLFDEP 163
Cdd:PRK03695  93 ---HQPD---------KTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLqvwpdINPagQLLLLDEP 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 164 LSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK03695 161 MNSLDVAQQAALDRLLSELCQQ-GIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPE 224
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
8-207 7.03e-16

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 78.70  E-value: 7.03e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 EL-KNVTKRFGTNTVidDL-SLSIPQGSMVT-LLGPSGCGKTTVLRLVAGLEKPTEGRMFIDG--EDVTDR--------- 73
Cdd:PRK13409  74 ELeEEPVHRYGVNGF--KLyGLPIPKEGKVTgILGPNGIGKTTAVKILSGELIPNLGDYEEEPswDEVLKRfrgtelqny 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  74 --SIQQRDICMVF--QSYALFPhMSLGDNVGYGLKmlglpKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALAR 149
Cdd:PRK13409 152 fkKLYNGEIKVVHkpQYVDLIP-KVFKGKVRELLK-----KVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIAA 225

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 150 ALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDqseaFAVSDMV 207
Cdd:PRK13409 226 ALLRDADFYFFDEPTSYLDIRQRLNVARLIRELAE--GKYVLVVEHD----LAVLDYL 277
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 7-198 1.92e-15

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 77.76  E-value: 1.92e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVtkRFGTNTVID-----DLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFI-DGEDVTDRSIQ--QR 78
Cdd:PTZ00265  383 IQFKNV--RFHYDTRKDveiykDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIInDSHNLKDINLKwwRS 460

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   79 DICMVFQSYALFPHmSLGDNVGYGLKML---------------------------------------------GLPKAEI 113
Cdd:PTZ00265  461 KIGVVSQDPLLFSN-SIKNNIKYSLYSLkdlealsnyynedgndsqenknkrnscrakcagdlndmsnttdsnELIEMRK 539

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  114 RKRVDEALELVD----------LAGFADRF-------VDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMR 176
Cdd:PTZ00265  540 NYQTIKDSEVVDvskkvlihdfVSALPDKYetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQ 619

                         250       260
                  ....*....|....*....|..
gi 757596975  177 EKIRELQQQFNITSLYVTHDQS 198
Cdd:PTZ00265  620 KTINNLKGNENRITIIIAHRLS 641
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
5-231 2.40e-15

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 75.93  E-value: 2.40e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   5 NFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVlRLVAGLEKPTEGR------MFIDGEDVTDRSIQQR 78
Cdd:NF000106  12 NAVEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRrpwrf*TWCANRRALRRTIG*H 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 DICMVFQSYALfphmSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVL 158
Cdd:NF000106  91 RPVR*GRRESF----SGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVL 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 159 LFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASR 231
Cdd:NF000106 167 YLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVGGR 238
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 9-196 7.38e-15

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 75.54  E-value: 7.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   9 LKNVTKRFGTNTVI-DDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDgEDVTdrsiqqrdICMVFQSY 87
Cdd:PRK11819   9 MNRVSKVVPPKKQIlKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPA-PGIK--------VGYLPQEP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  88 ALFPHMSLGDNVGYGLK--------------MLGLPKAEIRKRVDEALEL---------------VDLAGFA------DR 132
Cdd:PRK11819  80 QLDPEKTVRENVEEGVAevkaaldrfneiyaAYAEPDADFDALAAEQGELqeiidaadawdldsqLEIAMDAlrcppwDA 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 133 FVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDAnlrrsmrEKIRELQQ---QFNITSLYVTHD 196
Cdd:PRK11819 160 KVTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDA-------ESVAWLEQflhDYPGTVVAVTHD 219
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 8-214 8.26e-15

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 75.04  E-value: 8.26e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVT---DRSIQQRDICMVF 84
Cdd:PRK10762   6 QLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTfngPKSSQEAGIGIIH 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYALFPHMSLGDNVGYGL----KMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLF 160
Cdd:PRK10762  86 QELNLIPQLTIAENIFLGRefvnRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIM 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 757596975 161 DEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGK 214
Cdd:PRK10762 166 DEPTDALTDTETESLFRVIRELKSQ-GRGIVYISHRLKEIFEICDDVTVFRDGQ 218
PLN03211 PLN03211
ABC transporter G-25; Provisional
 11-219 1.91e-14

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 74.15  E-value: 1.91e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  11 NVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPT--EGRMFIDGEDVTDRSIqqRDICMVFQSYA 88
Cdd:PLN03211  73 DETRQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNnfTGTILANNRKPTKQIL--KRTGFVTQDDI 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  89 LFPHMSLGDNVGYgLKMLGLPKAEIRK-RVDEALELVDLAGFA--------DRFVDQISGGQQQRVALARALILKPKVLL 159
Cdd:PLN03211 151 LYPHLTVRETLVF-CSLLRLPKSLTKQeKILVAESVISELGLTkcentiigNSFIRGISGGERKRVSIAHEMLINPSLLI 229

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 160 FDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:PLN03211 230 LDEPTSGLDATAAYRLVLTLGSLAQKGKTIVTSMHQPSSRVYQMFDSVLVLSEGRCLFFG 289
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 22-215 2.61e-14

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 73.50  E-value: 2.61e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQR-DICMVFQSY-----ALFPHMSL 95
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGlANGIVYISEdrkrdGLVLGMSV 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  96 GDNVGygLKMLG-LPKAEIRKRVDEALELVDlaGFADRF------VDQI----SGGQQQRVALARALILKPKVLLFDEPL 164
Cdd:PRK10762 348 KENMS--LTALRyFSRAGGSLKHADEQQAVS--DFIRLFniktpsMEQAigllSGGNQQKVAIARGLMTRPKVLILDEPT 423

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 757596975 165 SNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:PRK10762 424 RGVDVGAKKEIYQLINQFKAE-GLSIILVSSEMPEVLGMSDRILVMHEGRI 473
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 7-227 5.11e-14

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 73.44  E-value: 5.11e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975     7 VELKNVTKRF--GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QRDICM 82
Cdd:TIGR00957 1285 VEFRNYCLRYreDLDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHdlRFKITI 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    83 VFQSYALFP---HMSLGDNVGYGlkmlglpkaeiRKRVDEALELVDLAGFADRFVDQI-----------SGGQQQRVALA 148
Cdd:TIGR00957 1365 IPQDPVLFSgslRMNLDPFSQYS-----------DEEVWWALELAHLKTFVSALPDKLdhecaeggenlSVGQRQLVCLA 1433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRelqQQF-NITSLYVTHDQSEAFAVSdMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:TIGR00957 1434 RALLRKTKILVLDEATAAVDLETDNLIQSTIR---TQFeDCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNLLQQ 1509
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
7-236 8.49e-14

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 71.37  E-value: 8.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN----TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKP----TEGRMFIDGEDVTDRSIQQR 78
Cdd:PRK15093   4 LDIRNLTIEFKTSdgwvKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDnwrvTADRMRFDDIDLLRLSPRER 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 ------DICMVFQ--SYALFPHMSLGDNV-----GYGLKMLGLPKAEIRKRvdEALELVDLAGFADR------FVDQISG 139
Cdd:PRK15093  84 rklvghNVSMIFQepQSCLDPSERVGRQLmqnipGWTYKGRWWQRFGWRKR--RAIELLHRVGIKDHkdamrsFPYELTE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 140 GQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:PRK15093 162 GECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETA 241

                        250       260
                 ....*....|....*....|....
gi 757596975 220 SPQEL-------YRQPASRFMASF 236
Cdd:PRK15093 242 PSKELvttphhpYTQALIRAIPDF 265
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
26-215 1.02e-13

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 71.87  E-value: 1.02e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  26 SLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRS----IQQRdicMVF-----QSYALFPHMSLG 96
Cdd:PRK11288 273 SFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSprdaIRAG---IMLcpedrKAEGIIPVHSVA 349

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  97 DNVGYGLKMLGLPKAEIRKRVDEAlelvdlaGFADRFVDQ--------------ISGGQQQRVALARALILKPKVLLFDE 162
Cdd:PRK11288 350 DNINISARRHHLRAGCLINNRWEA-------ENADRFIRSlniktpsreqlimnLSGGNQQKAILGRWLSEDMKVILLDE 422

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 757596975 163 PLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:PRK11288 423 PTRGIDVGAKHEIYNVIYELAAQ-GVAVLFVSSDLPEVLGVADRIVVMREGRI 474
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 7-224 1.61e-13

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 69.88  E-value: 1.61e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF--GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTV----LRLVAglekpTEGRMFIDGEDVTDRSIQQ--R 78
Cdd:cd03289    3 MTVKDLTAKYteGGNAVLENISFSISPGQRVGLLGRTGSGKSTLlsafLRLLN-----TEGDIQIDGVSWNSVPLQKwrK 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 DICMVFQSYALFPHmSLGDNVG-YGlkmlGLPKAEIRKRVDEalelVDLAGFADRFVDQI-----------SGGQQQRVA 146
Cdd:cd03289   78 AFGVIPQKVFIFSG-TFRKNLDpYG----KWSDEEIWKVAEE----VGLKSVIEQFPGQLdfvlvdggcvlSHGHKQLMC 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 147 LARALILKPKVLLFDEPLSNLDANLRRSMRekiRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:cd03289  149 LARSVLSKAKILLLDEPSAHLDPITYQVIR---KTLKQAFADCTVILSEHRIEAMLECQRFLVIEENKVRQYDSIQKL 223
PLN03130 PLN03130
ABC transporter C family member; Provisional
 24-224 1.70e-13

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 71.69  E-value: 1.70e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   24 DLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGlEKPTegrmfidgedVTDRSIQQR-DICMVFQSYALFpHMSLGDNVgyg 102
Cdd:PLN03130  635 NINLDVPVGSLVAIVGSTGEGKTSLISAMLG-ELPP----------RSDASVVIRgTVAYVPQVSWIF-NATVRDNI--- 699

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  103 lkMLGLPKAEIR--KRVDEA-----LELV---DLAGFADRFVDqISGGQQQRVALARALILKPKVLLFDEPLSNLDANLR 172
Cdd:PLN03130  700 --LFGSPFDPERyeRAIDVTalqhdLDLLpggDLTEIGERGVN-ISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVG 776

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 757596975  173 RSMREKI--RELQQQfniTSLYVThDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:PLN03130  777 RQVFDKCikDELRGK---TRVLVT-NQLHFLSQVDRIILVHEGMIKEEGTYEEL 826
PLN03232 PLN03232
ABC transporter C family member; Provisional
 7-241 1.94e-13

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 71.55  E-value: 1.94e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRF--GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QRDICM 82
Cdd:PLN03232 1235 IKFEDVHLRYrpGLPPVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTdlRRVLSI 1314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   83 VFQSYALFphmslGDNVGYGLKML------GLPKAEIRKRVDEALELVDLAGFADRFV--DQISGGQQQRVALARALILK 154
Cdd:PLN03232 1315 IPQSPVLF-----SGTVRFNIDPFsehndaDLWEALERAHIKDVIDRNPFGLDAEVSEggENFSVGQRQLLSLARALLRR 1389

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  155 PKVLLFDEPLSNLDANLRRSMREKIRElqqQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRF-- 232
Cdd:PLN03232 1390 SKILVLDEATASVDVRTDSLIQRTIRE---EFKSCTMLVIAHRLNTIIDCDKILVLSSGQVLEYDSPQELLSRDTSAFfr 1466


                  ....*....
gi 757596975  233 MASFMGDAN 241
Cdd:PLN03232 1467 MVHSTGPAN 1475
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 22-213 2.00e-13

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 68.51  E-value: 2.00e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDICMVFQ-SYALFPHMSLGDNVG 100
Cdd:cd03290   17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRYSvAYAAQKPWLLNATVE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 101 YGLkMLGLPKAEIR-KRVDEALEL---VDLAGFAD------RFVDqISGGQQQRVALARALILKPKVLLFDEPLSNLDAN 170
Cdd:cd03290   97 ENI-TFGSPFNKQRyKAVTDACSLqpdIDLLPFGDqteigeRGIN-LSGGQRQRICVARALYQNTNIVFLDDPFSALDIH 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 757596975 171 LRRS-MREKIRELQQQFNITSLYVTHdQSEAFAVSDMVLVMNKG 213
Cdd:cd03290  175 LSDHlMQEGILKFLQDDKRTLVLVTH-KLQYLPHADWIIAMKDG 217
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
18-228 2.61e-13

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 70.51  E-value: 2.61e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  18 TNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QRDICMVFQSYALFPHmSL 95
Cdd:PRK10789 327 DHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDswRSRLAVVSQTPFLFSD-TV 405

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  96 GDNVGyglkmLGLPKAEiRKRVDEALELVDL--------AGF----ADRFVdQISGGQQQRVALARALILKPKVLLFDEP 163
Cdd:PRK10789 406 ANNIA-----LGRPDAT-QQEIEHVARLASVhddilrlpQGYdtevGERGV-MLSGGQKQRISIARALLLNAEILILDDA 478

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 164 LSNLDANLRRSMREKIRELQQQFniTSLYVTHDQSeAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:PRK10789 479 LSAVDGRTEHQILHNLRQWGEGR--TVIISAHRLS-ALTEASEILVMQHGHIAQRGNHDQLAQQS 540
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 22-227 2.91e-13

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 70.69  E-value: 2.91e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEdvtdrsiqqrdICMVFQSYALFPHMSLGDNVGY 101
Cdd:PRK13545  40 LNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGS-----------AALIAISSGLNGQLTGIENIEL 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 102 GLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRE 181
Cdd:PRK13545 109 KGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLDKMNE 188

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 757596975 182 LQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL---YRQ 227
Cdd:PRK13545 189 FKEQ-GKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVvdhYDE 236
PLN03232 PLN03232
ABC transporter C family member; Provisional
 18-226 5.73e-13

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 70.00  E-value: 5.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   18 TNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEgrmfidgedvtdrsiqqrDICMVFQ-SYALFPHMS-- 94
Cdd:PLN03232  629 SKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAE------------------TSSVVIRgSVAYVPQVSwi 690

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   95 ----LGDNVGYGLKmlgLPKAEIRKRVD-----EALELV---DLAGFADRFVDqISGGQQQRVALARALILKPKVLLFDE 162
Cdd:PLN03232  691 fnatVRENILFGSD---FESERYWRAIDvtalqHDLDLLpgrDLTEIGERGVN-ISGGQKQRVSMARAVYSNSDIYIFDD 766

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975  163 PLSNLDANLRRSMREKI--RELQQQfniTSLYVThDQSEAFAVSDMVLVMNKGKIMQLGSPQELYR 226
Cdd:PLN03232  767 PLSALDAHVAHQVFDSCmkDELKGK---TRVLVT-NQLHFLPLMDRIILVSEGMIKEEGTFAELSK 828
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 8-196 8.83e-13

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 69.21  E-value: 8.83e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   8 ELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMfidgedvtdRSIQQRDICMvFQSY 87
Cdd:PRK11147 321 EMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRI---------HCGTKLEVAY-FDQH 390

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  88 --ALFPHMSLGDNVGYGlkmlglpKAEI----RKRvdEALelvdlaGFADRF----------VDQISGGQQQRVALARaL 151
Cdd:PRK11147 391 raELDPEKTVMDNLAEG-------KQEVmvngRPR--HVL------GYLQDFlfhpkramtpVKALSGGERNRLLLAR-L 454

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 757596975 152 ILKPKVLL-FDEPLSNLDAnlrrSMREKIRELQQQFNITSLYVTHD 196
Cdd:PRK11147 455 FLKPSNLLiLDEPTNDLDV----ETLELLEELLDSYQGTVLLVSHD 496
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 9-245 9.40e-13

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 69.55  E-value: 9.40e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975     9 LKNVTKRF--GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKpTEGRMFIDGEDVTDRSIQQ--RDICMVF 84
Cdd:TIGR01271 1220 VQGLTAKYteAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGVSWNSVTLQTwrKAFGVIP 1298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    85 QSYALF---------PHMSLGDNvgyglkmlglpkaEIRKRVDEalelVDLAGFADRFVDQ-----------ISGGQQQR 144
Cdd:TIGR01271 1299 QKVFIFsgtfrknldPYEQWSDE-------------EIWKVAEE----VGLKSVIEQFPDKldfvlvdggyvLSNGHKQL 1361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   145 VALARALILKPKVLLFDEPLSNLDANLRRSMRekiRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:TIGR01271 1362 MCLARSILSKAKILLLDEPSAHLDPVTLQIIR---KTLKQSFSNCTVILSEHRVEALLECQQFLVIEGSSVKQYDSIQKL 1438

                          250       260
                   ....*....|....*....|...
gi 757596975   225 YRQpASRFMASF--MGDANIFPA 245
Cdd:TIGR01271 1439 LNE-TSLFKQAMsaADRLKLFPL 1460
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
21-228 1.29e-12

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 67.62  E-value: 1.29e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  21 VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKP----TEGRMFIDGEDVTDRSIQQR------DICMVFQ--SYA 88
Cdd:COG4170   22 AVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDnwhvTADRFRWNGIDLLKLSPRERrkiigrEIAMIFQepSSC 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  89 LFPHMSLGDNVgyglkMLGLPKAEI----------RKRvdEALELVDLAGFADR------FVDQISGGQQQRVALARALI 152
Cdd:COG4170  102 LDPSAKIGDQL-----IEAIPSWTFkgkwwqrfkwRKK--RAIELLHRVGIKDHkdimnsYPHELTEGECQKVMIAMAIA 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757596975 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQP 228
Cdd:COG4170  175 NQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVESGPTEQILKSP 250
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 61-211 1.62e-12

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 68.90  E-value: 1.62e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   61 GRMFIDGEDVTDRSIQQ-RDI-CMVFQSYALFpHMSLGDNVGYGlkmlglPKAEIRKRVDEALELVDLAGFADRFVDQ-- 136
Cdd:PTZ00265 1277 GKILLDGVDICDYNLKDlRNLfSIVSQEPMLF-NMSIYENIKFG------KEDATREDVKRACKFAAIDEFIESLPNKyd 1349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  137 ---------ISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHdQSEAFAVSDMV 207
Cdd:PTZ00265 1350 tnvgpygksLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAH-RIASIKRSDKI 1428


                  ....
gi 757596975  208 LVMN 211
Cdd:PTZ00265 1429 VVFN 1432
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
7-219 2.97e-12

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 65.99  E-value: 2.97e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRF--------------------GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFID 66
Cdd:PRK13546   5 VNIKNVTKEYriyrtnkermkdalipkhknKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRN 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  67 GEdvtdrsiqqrdICMVFQSYALFPHMSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVA 146
Cdd:PRK13546  85 GE-----------VSVIAISAGLSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLG 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975 147 LARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLG 219
Cdd:PRK13546 154 FSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEQ-NKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYG 225
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
7-196 3.63e-12

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 67.14  E-value: 3.63e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGtntvidDLSLS-----IPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDgEDVTDRSiQ--QRD 79
Cdd:PRK13409 341 VEYPDLTKKLG------DFSLEveggeIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE-LKISYKP-QyiKPD 412

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  80 ICMVFQSYAlfphMSLGDNVG---YglkmlglpKAEIRKRvdeaLELVDLagfADRFVDQISGGQQQRVALARALILKPK 156
Cdd:PRK13409 413 YDGTVEDLL----RSITDDLGssyY--------KSEIIKP----LQLERL---LDKNVKDLSGGELQRVAIAACLSRDAD 473

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 757596975 157 VLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHD 196
Cdd:PRK13409 474 LYLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHD 513
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 29-241 5.64e-12

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 63.36  E-value: 5.64e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  29 IPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTdrsiqqrdicmvfqsyalfphmslgdnvgyglkmlgl 108
Cdd:cd03222   22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGITPV------------------------------------- 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 109 pkaeirkrvdealelvdlagFADRFVDqISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNI 188
Cdd:cd03222   65 --------------------YKPQYID-LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKK 123

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 189 TSLYVTHDQSEAFAVSDMVLVM--NKGKIMQLGSPQELyRQPASRFMASFMGDAN 241
Cdd:cd03222  124 TALVVEHDLAVLDYLSDRIHVFegEPGVYGIASQPKGT-REGINRFLRGYLITFR 177
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 9-214 5.96e-12

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 66.29  E-value: 5.96e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   9 LKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ---RDICMVFQ 85
Cdd:PRK10982   1 MSNISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEaleNGISMVHQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  86 SYALFPHMSLGDNV---GYGLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQISGGQQQRVALARALILKPKVLLFDE 162
Cdd:PRK10982  81 ELNLVLQRSVMDNMwlgRYPTKGMFVDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDE 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 757596975 163 PLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGK 214
Cdd:PRK10982 161 PTSSLTEKEVNHLFTIIRKLKER-GCGIVYISHKMEEIFQLCDEITILRDGQ 211
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 20-223 6.81e-12

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 66.67  E-value: 6.81e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    20 TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVA----GLEKPTEGRMFIDGEDVTDRSIQQR-DICMVFQSYALFPHMS 94
Cdd:TIGR00956   75 DILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIAsntdGFHIGVEGVITYDGITPEEIKKHYRgDVVYNAETDVHFPHLT 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    95 LGDNVGYGLKM-------LGLPKAEIRKRVDEalelVDLAGFA----------DRFVDQISGGQQQRVALARALILKPKV 157
Cdd:TIGR00956  155 VGETLDFAARCktpqnrpDGVSREEYAKHIAD----VYMATYGlshtrntkvgNDFVRGVSGGERKRVSIAEASLGGAKI 230

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   158 LLFDEPLSNLDANlrrSMREKIRELQQQFNI--TSLYVTHDQS--EAFAVSDMVLVMNKGKIMQLGSPQE 223
Cdd:TIGR00956  231 QCWDNATRGLDSA---TALEFIRALKTSANIldTTPLVAIYQCsqDAYELFDKVIVLYEGYQIYFGPADK 297
TOBE_2 pfam08402
TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the ...
 274-345 9.37e-12

TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the C-terminal strand of each domain is supplied by the partner. Probably involved in the recognition of small ligands such as molybdenum and sulphate. Found in ABC transporters immediately after the ATPase domain. In this family a strong RPE motif is found at the presumed N-terminus of the domain.


Pssm-ID: 462465 [Multi-domain]  Cd Length: 73  Bit Score: 59.94  E-value: 9.37e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757596975  274 VGVRPEAITLSlQGDDSQRCTVTHVAYMGPQYEVTVDWHGQSMLL--QINATQLQPTVGENLYLQIHPYGMFIL 345
Cdd:pfam08402   1 LAIRPEKIRLA-AAANGLSGTVTDVEYLGDHTRYHVELAGGEELVvrVPNAHARPPAPGDRVGLGWDPEDAHVL 73
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 7-196 1.37e-11

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 65.58  E-value: 1.37e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGtntvidDLSLSIPQGSM-----VTLLGPSGCGKTTVLRLVAGLEKPTEGRMFidgEDVTdrsI----Q- 76
Cdd:COG1245  342 VEYPDLTKSYG------GFSLEVEGGEIregevLGIVGPNGIGKTTFAKILAGVLKPDEGEVD---EDLK---IsykpQy 409

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  77 -QRDICMVFQSYalfphmsLGDNVG--YGLKMLglpKAEIRKRvdeaLELVDLAgfaDRFVDQISGGQQQRVALARALIL 153
Cdd:COG1245  410 iSPDYDGTVEEF-------LRSANTddFGSSYY---KTEIIKP----LGLEKLL---DKNVKDLSGGELQRVAIAACLSR 472

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 757596975 154 KPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHD 196
Cdd:COG1245  473 DADLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDHD 515
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 19-172 9.41e-11

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 60.27  E-value: 9.41e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  19 NTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIdgedvtdRSIQQRDICMVFQSYalfphmsLGDN 98
Cdd:PRK13541  13 QKNLFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYY-------KNCNINNIAKPYCTY-------IGHN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  99 VGYGLKMLGLPKAEIRKRVDEALELVD-------LAGFADRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANL 171
Cdd:PRK13541  79 LGLKLEMTVFENLKFWSEIYNSAETLYaaihyfkLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKEN 158


                 .
gi 757596975 172 R 172
Cdd:PRK13541 159 R 159
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 16-198 1.23e-10

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 62.66  E-value: 1.23e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  16 FGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRsIQQ---RDIC-MVF------- 84
Cdd:PRK11147  13 FSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIVAR-LQQdppRNVEgTVYdfvaegi 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 --QSYALFPHMSLGDNVG--YGLKMLG-LPKAEIR----------KRVDEALELVDLAgfADRFVDQISGGQQQRVALAR 149
Cdd:PRK11147  92 eeQAEYLKRYHDISHLVEtdPSEKNLNeLAKLQEQldhhnlwqleNRINEVLAQLGLD--PDAALSSLSGGWLRKAALGR 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 757596975 150 ALILKPKVLLFDEPLSNLDAnlrrsmrEKIRELQQ---QFNITSLYVTHDQS 198
Cdd:PRK11147 170 ALVSNPDVLLLDEPTNHLDI-------ETIEWLEGflkTFQGSIIFISHDRS 214
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 5-196 2.16e-10

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 61.83  E-value: 2.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   5 NFVELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRM------------------FID 66
Cdd:PRK15064 318 NALEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVkwsenanigyyaqdhaydFEN 397

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  67 GEDVTDRSIQQR----DICMVfqsyalfpHMSLGdnvgyglKMLgLPKAEIRKRvdealelvdlagfadrfVDQISGGQQ 142
Cdd:PRK15064 398 DLTLFDWMSQWRqegdDEQAV--------RGTLG-------RLL-FSQDDIKKS-----------------VKVLSGGEK 444

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975 143 QRVALARALILKPKVLLFDEPLSNLDanlrrsMrEKIRELQ---QQFNITSLYVTHD 196
Cdd:PRK15064 445 GRMLFGKLMMQKPNVLVMDEPTNHMD------M-ESIESLNmalEKYEGTLIFVSHD 494
PTZ00243 PTZ00243
ABC transporter; Provisional
 24-235 3.61e-10

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 61.33  E-value: 3.61e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   24 DLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFidgedvtdrsiQQRDICMVFQSyALFPHMSLGDNVGYGl 103
Cdd:PTZ00243  678 DVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVW-----------AERSIAYVPQQ-AWIMNATVRGNILFF- 744

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  104 kmlglpKAEIRKRVDEALEL----VDLAGFADRFVDQI-------SGGQQQRVALARALILKPKVLLFDEPLSNLDANL- 171
Cdd:PTZ00243  745 ------DEEDAARLADAVRVsqleADLAQLGGGLETEIgekgvnlSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVg 818

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757596975  172 RRSMREKIreLQQQFNITSLYVTHdQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRFMAS 235
Cdd:PTZ00243  819 ERVVEECF--LGALAGKTRVLATH-QVHVVPRADYVVALGDGRVEFSGSSADFMRTSLYATLAA 879
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 19-238 6.34e-10

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 59.10  E-value: 6.34e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  19 NTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEdvtdrsiqqrdICMVFQSYALFPHmSLGDN 98
Cdd:cd03291   50 APVLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR-----------ISFSSQFSWIMPG-TIKEN 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  99 VgyglkMLGLPKAEIR-KRVDEALEL-VDLAGFADRfvDQI---------SGGQQQRVALARALILKPKVLLFDEPLSNL 167
Cdd:cd03291  118 I-----IFGVSYDEYRyKSVVKACQLeEDITKFPEK--DNTvlgeggitlSGGQRARISLARAVYKDADLYLLDSPFGYL 190

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757596975 168 DANLRRSMREK-IRELQQqfNITSLYVThDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQPASrFMASFMG 238
Cdd:cd03291  191 DVFTEKEIFEScVCKLMA--NKTRILVT-SKMEHLKKADKILILHEGSSYFYGTFSELQSLRPD-FSSKLMG 258
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 7-200 1.01e-09

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 59.64  E-value: 1.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGlEKPTE--------GRMFIDGEDVTDrsIQQR 78
Cdd:PRK10938 261 IVLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG-DHPQGysndltlfGRRRGSGETIWD--IKKH 337

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  79 dICMVFQSYalfpHM-----SLGDNV---GYgLKMLGLPKAEIRKRVDEALELVDLAGFADRFVDQ----ISGGQQQRVA 146
Cdd:PRK10938 338 -IGYVSSSL----HLdyrvsTSVRNVilsGF-FDSIGIYQAVSDRQQKLAQQWLDILGIDKRTADApfhsLSWGQQRLAL 411

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 757596975 147 LARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEA 200
Cdd:PRK10938 412 IVRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLISEGETQLLFVSHHAEDA 465
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 21-224 2.42e-09

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 58.77  E-value: 2.42e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    21 VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEdvtdrsiqqrdICMVFQSYALFPHmSLGDNVg 100
Cdd:TIGR01271  441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGR-----------ISFSPQTSWIMPG-TIKDNI- 507

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   101 yglkMLGLPKAEIRKR-VDEALEL-VDLAGFADRfvDQI---------SGGQQQRVALARALILKPKVLLFDEPLSNLDA 169
Cdd:TIGR01271  508 ----IFGLSYDEYRYTsVIKACQLeEDIALFPEK--DKTvlgeggitlSGGQRARISLARAVYKDADLYLLDSPFTHLDV 581

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 757596975   170 NLRRSMREKIReLQQQFNITSLYVThDQSEAFAVSDMVLVMNKGKIMQLGSPQEL 224
Cdd:TIGR01271  582 VTEKEIFESCL-CKLMSNKTRILVT-SKLEHLKKADKILLLHEGVCYFYGTFSEL 634
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 7-213 3.03e-09

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 56.10  E-value: 3.03e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRfgtntVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKP--TEGRMFIDGedvtdrsiQQRDICmvF 84
Cdd:cd03232   13 VPVKGGKRQ-----LLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKTAgvITGEILING--------RPLDKN--F 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  85 QSYalfphmslgdnVGYGLKM-LGLPKAEIRkrvdEALEL-VDLAGfadrfvdqISGGQQQRVALARALILKPKVLLFDE 162
Cdd:cd03232   78 QRS-----------TGYVEQQdVHSPNLTVR----EALRFsALLRG--------LSVEQRKRLTIGVELAAKPSILFLDE 134

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 757596975 163 PLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEA-FAVSDMVLVMNKG 213
Cdd:cd03232  135 PTSGLDSQAAYNIVRFLKKLADS-GQAILCTIHQPSASiFEKFDRLLLLKRG 185
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 31-196 4.45e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 54.69  E-value: 4.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    31 QGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMF-IDGEDVTDRSIQQRDICMVFQSYAlfphmslgdnvgyglkmlglp 109
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIyIDGEDILEEVLDQLLLIIVGGKKA--------------------- 59

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   110 kaeirkrvdealelvdlagfadrfvdQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIR-----ELQQ 184
Cdd:smart00382  60 --------------------------SGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrlllLLKS 113

                          170
                   ....*....|..
gi 757596975   185 QFNITSLYVTHD 196
Cdd:smart00382 114 EKNLTVILTTND 125
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 32-182 4.48e-09

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 58.20  E-value: 4.48e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    32 GSMVTLLGPSGCGKTTVL-----RLVAGLekPTEGRMFIDGE--DVT-DRSI---QQRDI---------CMVFQSYALFP 91
Cdd:TIGR00956  789 GTLTALMGASGAGKTTLLnvlaeRVTTGV--ITGGDRLVNGRplDSSfQRSIgyvQQQDLhlptstvreSLRFSAYLRQP 866

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    92 HmslgdnvgyglkmlGLPKAEIRKRVDEALELVDLAGFADRFVDQISGG----QQQRVALARALILKPKVLLF-DEPLSN 166
Cdd:TIGR00956  867 K--------------SVSKSEKMEYVEEVIKLLEMESYADAVVGVPGEGlnveQRKRLTIGVELVAKPKLLLFlDEPTSG 932

                          170
                   ....*....|....*.
gi 757596975   167 LDANLRRSMREKIREL 182
Cdd:TIGR00956  933 LDSQTAWSICKLMRKL 948
PLN03073 PLN03073
ABC transporter F family; Provisional
 17-215 4.51e-09

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 57.95  E-value: 4.51e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  17 GTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMF--------------IDGEDVTDRSIQQRDICm 82
Cdd:PLN03073 520 GGPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFrsakvrmavfsqhhVDGLDLSSNPLLYMMRC- 598

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 vfqsyalFPhmslgdnvgyglkmlGLPKAEIRKRvdeaLELVDLAG-FADRFVDQISGGQQQRVALARALILKPKVLLFD 161
Cdd:PLN03073 599 -------FP---------------GVPEQKLRAH----LGSFGVTGnLALQPMYTLSGGQKSRVAFAKITFKKPHILLLD 652

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 757596975 162 EPLSNLDANLRRSMREKIRELQQQFnitsLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:PLN03073 653 EPSNHLDLDAVEALIQGLVLFQGGV----LMVSHDEHLISGSVDELWVVSEGKV 702
PLN03130 PLN03130
ABC transporter C family member; Provisional
 7-241 1.12e-08

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 56.67  E-value: 1.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975    7 VELKNVTKRFGTN--TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QRDICM 82
Cdd:PLN03130 1238 IKFEDVVLRYRPElpPVLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMdlRKVLGI 1317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   83 VFQSYALFphmslGDNVGYGLKmlglPKAEiRKRVD--EALELVDLAGFADRFV-----------DQISGGQQQRVALAR 149
Cdd:PLN03130 1318 IPQAPVLF-----SGTVRFNLD----PFNE-HNDADlwESLERAHLKDVIRRNSlgldaevseagENFSVGQRQLLSLAR 1387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  150 ALILKPKVLLFDEPLSNL----DANLRRSMREKIRelqqqfNITSLYVTHdQSEAFAVSDMVLVMNKGKIMQLGSPQELY 225
Cdd:PLN03130 1388 ALLRRSKILVLDEATAAVdvrtDALIQKTIREEFK------SCTMLIIAH-RLNTIIDCDRILVLDAGRVVEFDTPENLL 1460

                         250
                  ....*....|....*...
gi 757596975  226 RQPASRF--MASFMGDAN 241
Cdd:PLN03130 1461 SNEGSAFskMVQSTGAAN 1478
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 9-227 1.45e-08

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 56.33  E-value: 1.45e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   9 LKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMfidgedvtdrsiqqrdicmvfqsyA 88
Cdd:PRK10636 315 MEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEI------------------------G 370

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  89 LFPHMSLGDNVGYGLKMLGL---PKAEIRKRVDEALE--LVD-LAGFA---DRFVD---QISGGQQQRVALARALILKPK 156
Cdd:PRK10636 371 LAKGIKLGYFAQHQLEFLRAdesPLQHLARLAPQELEqkLRDyLGGFGfqgDKVTEetrRFSGGEKARLVLALIVWQRPN 450

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757596975 157 VLLFDEPLSNLDANLRRSMREKIRElqqqFNITSLYVTHDQSEAFAVSDMVLVMNKGKIMQLGSPQELYRQ 227
Cdd:PRK10636 451 LLLLDEPTNHLDLDMRQALTEALID----FEGALVVVSHDRHLLRSTTDDLYLVHDGKVEPFDGDLEDYQQ 517
PLN03073 PLN03073
ABC transporter F family; Provisional
 7-168 3.67e-08

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 54.87  E-value: 3.67e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVA-----GLEK--------------PTEGRMFIDG 67
Cdd:PLN03073 178 IHMENFSISVGGRDLIVDASVTLAFGRHYGLVGRNGTGKTTFLRYMAmhaidGIPKncqilhveqevvgdDTTALQCVLN 257

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  68 EDVTDRSIQQRDICMVFQSYALFPHMSLGDnvGYGLKMLGLPKAEIRKRVDEA---LELVD-----------LAGFA--- 130
Cdd:PLN03073 258 TDIERTQLLEEEAQLVAQQRELEFETETGK--GKGANKDGVDKDAVSQRLEEIykrLELIDaytaearaasiLAGLSftp 335

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 757596975 131 ---DRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLD 168
Cdd:PLN03073 336 emqVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLD 376
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 22-196 5.04e-08

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 51.94  E-value: 5.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  22 IDDLSLSIPQGSMVTLLGPSGCGKTTVLRlvAGLEKPTEgRMFIDGEDVTDRSIqqrdICMVFQSYALFphmslgdNVGY 101
Cdd:cd03238   11 LQNLDVSIPLNVLVVVTGVSGSGKSTLVN--EGLYASGK-ARLISFLPKFSRNK----LIFIDQLQFLI-------DVGL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 102 GLKMLGlpkaeirkrvdealelvdlagfadRFVDQISGGQQQRVALARALI--LKPKVLLFDEPLSNLDANLRRSMREKI 179
Cdd:cd03238   77 GYLTLG------------------------QKLSTLSGGELQRVKLASELFsePPGTLFILDEPSTGLHQQDINQLLEVI 132

                        170
                 ....*....|....*..
gi 757596975 180 RELQQQFNiTSLYVTHD 196
Cdd:cd03238  133 KGLIDLGN-TVILIEHN 148
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 11-196 8.29e-08

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 53.74  E-value: 8.29e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  11 NVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDG--------------ED--VTDRS 74
Cdd:PRK15064   6 NITMQFGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDPnerlgklrqdqfafEEftVLDTV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  75 I----------QQRDicmvfQSYALfPHMSLGDnvgyGLKMLGLP---------KAEIRkrvdeALELVDLAGFADRF-- 133
Cdd:PRK15064  86 ImghtelwevkQERD-----RIYAL-PEMSEED----GMKVADLEvkfaemdgyTAEAR-----AGELLLGVGIPEEQhy 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 134 --VDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANlrrsmreKIRELQQ---QFNITSLYVTHD 196
Cdd:PRK15064 151 glMSEVAPGWKLRVLLAQALFSNPDILLLDEPTNNLDIN-------TIRWLEDvlnERNSTMIIISHD 211
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 35-196 2.05e-07

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 50.68  E-value: 2.05e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  35 VTLL-GPSGCGKTTVLRLVaglekptegrmfidgedvtdrsiqqrdicmvfqSYALFPHMSLGDNVGYGL-KMLGlpKAE 112
Cdd:cd03240   24 LTLIvGQNGAGKTTIIEAL---------------------------------KYALTGELPPNSKGGAHDpKLIR--EGE 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 113 IRKRVDEALELV-----------------------DLAGFADRFVDQISGGQQQ------RVALARALILKPKVLLFDEP 163
Cdd:cd03240   69 VRAQVKLAFENAngkkytitrslailenvifchqgESNWPLLDMRGRCSGGEKVlasliiRLALAETFGSNCGILALDEP 148

                        170       180       190
                 ....*....|....*....|....*....|....
gi 757596975 164 LSNLDA-NLRRSMREKIRELQQQFNITSLYVTHD 196
Cdd:cd03240  149 TTNLDEeNIEESLAEIIEERKSQKNFQLIVITHD 182
PLN03140 PLN03140
ABC transporter G family member; Provisional
 32-169 2.81e-07

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 52.54  E-value: 2.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   32 GSMVTLLGPSGCGKTTVLRLVAGLEKP--TEGRMFIDG----EDVTDR---SIQQRDIcmvfQSyalfPHMSLGDNVGYG 102
Cdd:PLN03140  906 GVLTALMGVSGAGKTTLMDVLAGRKTGgyIEGDIRISGfpkkQETFARisgYCEQNDI----HS----PQVTVRESLIYS 977

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975  103 lKMLGLPKaEIRKR-----VDEALELVDLAGFADRFV-----DQISGGQQQRVALARALILKPKVLLFDEPLSNLDA 169
Cdd:PLN03140  978 -AFLRLPK-EVSKEekmmfVDEVMELVELDNLKDAIVglpgvTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDA 1052
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 7-219 4.78e-07

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 50.17  E-value: 4.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLE--KPTEGRMFIDGEDVTDRSIQQR---DIC 81
Cdd:PRK09580   2 LSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLELSPEDRageGIF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  82 MVFQSYALFPHMS----LGDNVGYGLKMLG---LPKAEIRKRVDEALELVDL-AGFADRFVDQ-ISGGQQQRVALARALI 152
Cdd:PRK09580  82 MAFQYPVEIPGVSnqffLQTALNAVRSYRGqepLDRFDFQDLMEEKIALLKMpEDLLTRSVNVgFSGGEKKRNDILQMAV 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757596975 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQS-EAFAVSDMVLVMNKGKIMQLG 219
Cdd:PRK09580 162 LEPELCILDESDSGLDIDALKIVADGVNSLRDG-KRSFIIVTHYQRiLDYIKPDYVHVLYQGRIVKSG 228
PTZ00243 PTZ00243
ABC transporter; Provisional
 15-232 3.01e-06

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 49.01  E-value: 3.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   15 RFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQ--RDICMVFQSYALFPH 92
Cdd:PTZ00243 1319 REGLPLVLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLRElrRQFSMIPQDPVLFDG 1398

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   93 mSLGDNVGyglKMLGLPKAEirkrVDEALELVDL--------AGFADRFVD---QISGGQQQRVALARALILK-PKVLLF 160
Cdd:PTZ00243 1399 -TVRQNVD---PFLEASSAE----VWAALELVGLrervasesEGIDSRVLEggsNYSVGQRQLMCMARALLKKgSGFILM 1470

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757596975  161 DEPLSNLDANLRRSMREKIRELQQQFN-ITSLYVTHdqseAFAVSDMVLVMNKGKIMQLGSPQELYRQPASRF 232
Cdd:PTZ00243 1471 DEATANIDPALDRQIQATVMSAFSAYTvITIAHRLH----TVAQYDKIIVMDHGAVAEMGSPRELVMNRQSIF 1539
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 137-215 6.58e-06

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 47.80  E-value: 6.58e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757596975 137 ISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDMVLVMNKGKI 215
Cdd:PRK10982 392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKK-DKGIIIISSEMPELLGITDRILVMSNGLV 469
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 7-239 1.54e-05

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 45.67  E-value: 1.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975   7 VELKNVTKRFGTN--TVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQ--QRDICM 82
Cdd:cd03288   20 IKIHDLCVRYENNlkPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHtlRSRLSI 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  83 VFQSYALFphmslGDNVGYGLKmlglPKAEIR-KRVDEALELVDLA-------GFADRFV----DQISGGQQQRVALARA 150
Cdd:cd03288  100 ILQDPILF-----SGSIRFNLD----PECKCTdDRLWEALEIAQLKnmvkslpGGLDAVVteggENFSVGQRQLFCLARA 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975 151 LILKPKVLLFDEPLSNLDANLRRSMREKIreLQQQFNITSLYVTHDQSEAFAvSDMVLVMNKGKIMQLGSPQELYRQPAS 230
Cdd:cd03288  171 FVRKSSILIMDEATASIDMATENILQKVV--MTAFADRTVVTIAHRVSTILD-ADLVLVLSRGILVECDTPENLLAQEDG 247


                 ....*....
gi 757596975 231 RFMASFMGD 239
Cdd:cd03288  248 VFASLVRTD 256
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 14-197 2.47e-05

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 43.89  E-value: 2.47e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  14 KRFGTNtvIDDLSLSIPQGSMVTLLGPSGCGKTTVLR---LVAGLEKPTEGRmfidgedvtdRSIQQRdicmvfqsyalf 90
Cdd:cd03227    5 GRFPSY--FVPNDVTFGEGSLTIITGPNGSGKSTILDaigLALGGAQSATRR----------RSGVKA------------ 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  91 phmslGDNVGYglkmlglpkaeirkrvdEALELVdlagfadRFVDQISGGQQQRVALARALIL---KPKVL-LFDEPLSN 166
Cdd:cd03227   61 -----GCIVAA-----------------VSAELI-------FTRLQLSGGEKELSALALILALaslKPRPLyILDEIDRG 111

                        170       180       190
                 ....*....|....*....|....*....|.
gi 757596975 167 LDANLRRSMREKIRELQQQFNITsLYVTHDQ 197
Cdd:cd03227  112 LDPRDGQALAEAILEHLVKGAQV-IVITHLP 141
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 15-168 2.81e-05

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 45.93  E-value: 2.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  15 RFGTNTVIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGlEKPTEGRMF--------------------------IDGe 68
Cdd:PRK10636  10 RRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKN-EISADGGSYtfpgnwqlawvnqetpalpqpaleyvIDG- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  69 dvtDRSIQQRDICMvfqsyalfpHMSLGDNVGYGL-----KMLGLPKAEIRKRvdeALELVDLAGFA----DRFVDQISG 139
Cdd:PRK10636  88 ---DREYRQLEAQL---------HDANERNDGHAIatihgKLDAIDAWTIRSR---AASLLHGLGFSneqlERPVSDFSG 152

                        170       180
                 ....*....|....*....|....*....
gi 757596975 140 GQQQRVALARALILKPKVLLFDEPLSNLD 168
Cdd:PRK10636 153 GWRMRLNLAQALICRSDLLLLDEPTNHLD 181
GguA NF040905
sugar ABC transporter ATP-binding protein;
21-163 3.12e-04

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 42.47  E-value: 3.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  21 VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAGLE--KPTEGRMFIDGEDVTDRSIQQ---RDICMVFQ---SYALfph 92
Cdd:NF040905 275 VVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGRSygRNISGTVFKDGKEVDVSTVSDaidAGLAYVTEdrkGYGL--- 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757596975  93 mSLGDNVGYGLKMLGLPKAEIRKRVDEALELVDLAGFADRF------VDQI----SGGQQQRVALARALILKPKVLLFDE 162
Cdd:NF040905 352 -NLIDDIKRNITLANLGKVSRRGVIDENEEIKVAEEYRKKMniktpsVFQKvgnlSGGNQQKVVLSKWLFTDPDVLILDE 430


                 .
gi 757596975 163 P 163
Cdd:NF040905 431 P 431
COG1373 COG1373
Predicted ATPase, AAA+ superfamily [General function prediction only];
21-87 7.13e-04

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440984 [Multi-domain]  Cd Length: 405  Bit Score: 41.08  E-value: 7.13e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757596975  21 VIDDLSLSIPQGSMVTLLGPSGCGKTTVLRLVAgleKPTEGRMFIDGEDVTDRSIQQRDICMVFQSY 87
Cdd:COG1373    9 ILDKLLKLLDNRKAVVITGPRQVGKTTLLKQLA---KELENILYINLDDPRLRALAEEDPDDLLEAL 72
aroK PRK00131
shikimate kinase; Reviewed
 31-78 9.75e-04

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 39.40  E-value: 9.75e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 757596975  31 QGSMVTLLGPSGCGKTTVLRLVA---GLEkptegrmFIDgedvTDRSIQQR 78
Cdd:PRK00131   3 KGPNIVLIGFMGAGKSTIGRLLAkrlGYD-------FID----TDHLIEAR 42
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 131-185 1.29e-03

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 40.38  E-value: 1.29e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 757596975 131 DRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQ 185
Cdd:PRK10938 130 DRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLASLHQS 184
OB_MalK pfam17912
MalK OB fold domain; This entry corresponds to one of two OB-fold domains found in the MalK ...
 241-281 3.65e-03

MalK OB fold domain; This entry corresponds to one of two OB-fold domains found in the MalK transport protein.


Pssm-ID: 465563 [Multi-domain]  Cd Length: 53  Bit Score: 35.25  E-value: 3.65e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 757596975  241 NIFPATLTHDSVNIFNYH----LPRPAQLAT---DNTEITVGVRPEAI 281
Cdd:pfam17912   6 NFLPATVVEDGLLVLGGGvtlpLPEGQVLALklyVGKEVILGIRPEHI 53
AAA_14 pfam13173
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 35-80 3.98e-03

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 463799 [Multi-domain]  Cd Length: 128  Bit Score: 36.80  E-value: 3.98e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 757596975   35 VTLLGPSGCGKTTVLRLVAGLEKPTEGRMFIDGEDVTDRSIQQRDI 80
Cdd:pfam13173   5 LVITGPRQVGKTTLLLQLIKELLPPENILYINLDDPRLLKLADFEL 50
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 35-78 5.28e-03

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 37.03  E-value: 5.28e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 757596975  35 VTLLGPSGCGKTTVLRLVA---GLEkptegrmFIDgedvTDRSIQQR 78
Cdd:COG0703    1 IVLIGMMGAGKSTVGRLLAkrlGLP-------FVD----TDAEIEER 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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