|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05355 |
PRK05355 |
3-phosphoserine/phosphohydroxythreonine transaminase; |
1-362 |
0e+00 |
|
3-phosphoserine/phosphohydroxythreonine transaminase;
Pssm-ID: 235428 Cd Length: 360 Bit Score: 703.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 1 MSQVYNFSAGPAMLPVEVMRRAEQEFCNWQGLGVSVMEVSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAHF 80
Cdd:PRK05355 1 MMRVYNFSAGPAMLPEEVLEQAQQELLDWNGSGMSVMEISHRSKEFEAVAEEAEADLRELLNIPDNYKVLFLQGGASLQF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 81 ATIPMNLLGGKTTADYIVSGYWSESAAKEAAKYCKPNVIQIAEEkDGVVSLKPMSEWPLSDDAAYVHYCPNETIGGLALH 160
Cdd:PRK05355 81 AMVPMNLLGGGKKADYVDTGSWSKKAIKEAKKYGEVNVAASSED-DGFTYIPPLDEWQLSDDAAYVHYTSNETIDGTEFH 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 161 EEPDFpKDKIIVADYSSSILSKPIDVSRFGIIYAGAQKNIGPAGLTIVIIREDLLGKASPQTPSVFDYTLLAKHDSMFNT 240
Cdd:PRK05355 160 ELPDT-GDVPLVADMSSDILSRPIDVSKFGLIYAGAQKNIGPAGLTIVIVREDLLGRALPSIPSMLDYKTHADNDSMYNT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 241 PPTFAWYLSGMVFKWLKEQGGLQEMAKRNYEKSQLLYNAIDDSQFYINRVAVENRSWMNVPFQMQNPALDAKFIEEAKEQ 320
Cdd:PRK05355 239 PPTFAIYLAGLVFKWLKEQGGVAAMEKRNQEKAALLYDAIDSSDFYRNPVAPEDRSRMNVPFTLADEELDKKFLAEAKAA 318
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 757598829 321 GLLSLKGHKVAGGMRASIYNAMPLAGVQALVDFMADFERHNA 362
Cdd:PRK05355 319 GLVGLKGHRSVGGMRASIYNAMPLEGVQALVDFMKEFERRHG 360
|
|
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
2-361 |
0e+00 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 638.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 2 SQVYNFSAGPAMLPVEVMRRAEQEFCNWQGLGVSVMEVSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAHFA 81
Cdd:COG1932 1 MRVYNFSAGPAKLPEEVLEQAQAELLDWNGSGMSVMEMSHRSKPFKAIVEEAEADLRELLGIPDGYEVLFLQGGATAQFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 82 TIPMNLLGGKTTADYIVSGYWSESAAKEAAKYCKPNVIQIAEEkDGVVSLKPMSEWPLSDDAAYVHYCPNETIGGLALHE 161
Cdd:COG1932 81 MVPMNLLRGGKKADYLVTGEWSKKAIKEAKKYGEVNVVASSED-DNFGYIPKPEEWQLSPDADYVHYTSNETITGVEFHE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 162 EPDFPkDKIIVADYSSSILSKPIDVSRFGIIYAGAQKNIGPAGLTIVIIREDLLGKASPQTPSVFDYTLLAKHDSMFNTP 241
Cdd:COG1932 160 LPDVG-DVPLVADMSSDILSRPVDVSKFGLIYAGAQKNIGPAGLTVVIVRPDLLGRAERAIPSMLDYKTHADNDSMYNTP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 242 PTFAWYLSGMVFKWLKEQGGLQEMAKRNYEKSQLLYNAIDDSQFYINRVAVENRSWMNVPFQMQNPALDAKFIEEAKEQG 321
Cdd:COG1932 239 PTFAIYLAGLVLKWLKEQGGLAAMEKRNAEKAALLYDWIDASDFYTNPVDPEDRSRMNVTFDLADEELDAAFLAEAKAAG 318
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 757598829 322 LLSLKGHKVAGGMRASIYNAMPLAGVQALVDFMADFERHN 361
Cdd:COG1932 319 LVGLKGHRSVGGMRASIYNAMPLEGVEALVDFMDEFERRH 358
|
|
| PSAT_like |
cd00611 |
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP) ... |
5-359 |
0e+00 |
|
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as a dimer and catalyzes the conversion of phosphohydroxypyruvate to phosphoserine.
Pssm-ID: 99736 [Multi-domain] Cd Length: 355 Bit Score: 577.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 5 YNFSAGPAMLPVEVMRRAEQEFCNWQGLGVSVMEVSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAHFATIP 84
Cdd:cd00611 1 INFSAGPAALPEEVLEQAQKELLDFNGLGMSVMEMSHRSKDFEAIVNEAESDLRELLNIPDNYKVLFLQGGATGQFAAVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 85 MNLLGGKTTADYIVSGYWSESAAKEAAKYCKPNVIQIAEEKDGVVSLKPMSEWPLSDDAAYVHYCPNETIGGLALHEEPD 164
Cdd:cd00611 81 LNLLGDKGTADYVVTGAWSAKAAKEAKRYGGVVVIVAAKEEGKYTKIPDVETWDLAPDAAYVHYCSNETIHGVEFDEVPD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 165 FPkDKIIVADYSSSILSKPIDVSRFGIIYAGAQKNIGPAGLTIVIIREDLLGKASPQTPSVFDYTLLAKHDSMFNTPPTF 244
Cdd:cd00611 161 TG-GVPLVADMSSNILSRPIDVSKFGVIYAGAQKNLGPAGVTVVIVRKDLLGKARKITPSMLNYKTHADNNSLYNTPPTF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 245 AWYLSGMVFKWLKEQGGLQEMAKRNYEKSQLLYNAIDDSQ-FYINRVAVENRSWMNVPFQMQNPALDAKFIEEAKEQGLL 323
Cdd:cd00611 240 AIYMMGLVLKWLKEQGGVEAMEKRNRQKAQLLYDTIDNSNgFYRGPVDKRARSRMNVPFRLGKEELEKEFLKEAEAAGMI 319
|
330 340 350
....*....|....*....|....*....|....*.
gi 757598829 324 SLKGHKVAGGMRASIYNAMPLAGVQALVDFMADFER 359
Cdd:cd00611 320 GLKGHRSVGGIRASIYNALSLEGVQALADFMKEFQK 355
|
|
| serC_1 |
TIGR01364 |
phosphoserine aminotransferase; This model represents the common form of the phosphoserine ... |
12-361 |
0e+00 |
|
phosphoserine aminotransferase; This model represents the common form of the phosphoserine aminotransferase SerC. The phosphoserine aminotransferase of the archaeon Methanosarcina barkeri and putative phosphoserine aminotransferase of Mycobacterium tuberculosis are represented by separate models. All are members of the class V aminotransferases (pfam00266). [Amino acid biosynthesis, Serine family]
Pssm-ID: 130431 Cd Length: 349 Bit Score: 553.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 12 AMLPVEVMRRAEQEFCNWQGLGVSVMEVSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAHFATIPMNLLGGK 91
Cdd:TIGR01364 1 AALPEEVLEQAQKELLNFNGTGMSVMEISHRSKEFEAVANEAESDLRELLNIPDNYEVLFLQGGATGQFAAVPLNLLAEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 92 TTADYIVSGYWSESAAKEAAKYCKPNVIQIAEEKDgVVSLKPMSEWPLSDDAAYVHYCPNETIGGLALHEEPDFpKDKII 171
Cdd:TIGR01364 81 KVADYIVTGAWSKKAAKEAKKYGVVNVVASGKEGN-YTKIPDPSTWEISEDAAYVHYCANETIHGVEFRELPDV-KNAPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 172 VADYSSSILSKPIDVSRFGIIYAGAQKNIGPAGLTIVIIREDLLGKASPQTPSVFDYTLLAKHDSMFNTPPTFAWYLSGM 251
Cdd:TIGR01364 159 VADMSSNILSRPIDVSKFGLIYAGAQKNIGPAGLTVVIVRKDLLGRASRITPSMLNYKIHAENDSMYNTPPTFAIYVSGL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 252 VFKWLKEQGGLQEMAKRNYEKSQLLYNAIDDSQ-FYINRVAVENRSWMNVPFQMQNPALDAKFIEEAKEQGLLSLKGHKV 330
Cdd:TIGR01364 239 VFKWLKEQGGVKAIEKRNQAKAQLLYDTIDNSNgFYRNPVDPRNRSRMNVVFTLGNEELEKRFLKEAEERGLVSLKGHRS 318
|
330 340 350
....*....|....*....|....*....|.
gi 757598829 331 AGGMRASIYNAMPLAGVQALVDFMADFERHN 361
Cdd:TIGR01364 319 VGGMRASIYNAMPLEGVQALVDFMKEFQKKH 349
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
4-350 |
1.81e-76 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 239.84 E-value: 1.81e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 4 VYNFSAGPAMLPVEVMRRAEQEFCNWQGLGVSvmEVSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAhFATI 83
Cdd:pfam00266 1 IYLDSAATTQKPQEVLDAIQEYYTDYNGNVHR--GVHTLGKEATQAYEEAREKVAEFINAPSNDEIIFTSGTTEA-INLV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 84 PMNL---LGGKTTADYIVSGYWSES-AAKEAAKYCKPNVIQIAEEKDGVVSLKPMsEWPLSDDAAYVHYCPNETIGGlAL 159
Cdd:pfam00266 78 ALSLgrsLKPGDEIVITEMEHHANLvPWQELAKRTGARVRVLPLDEDGLLDLDEL-EKLITPKTKLVAITHVSNVTG-TI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 160 HEEPDFPK-----DKIIVADYSSSILSKPIDVSRFGI--IYAGAQKNIGPAGLTIVIIREDLLGKASP--------QTPS 224
Cdd:pfam00266 156 QPVPEIGKlahqyGALVLVDAAQAIGHRPIDVQKLGVdfLAFSGHKLYGPTGIGVLYGRRDLLEKMPPllggggmiETVS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 225 vFDYTLLAKHDSMFN--TPPTFAWYLSGMVFKWLKEqGGLQEMAKRNYEKSQLLYNAIDDSQFYINRVAVENRSWMNVPF 302
Cdd:pfam00266 236 -LQESTFADAPWKFEagTPNIAGIIGLGAALEYLSE-IGLEAIEKHEHELAQYLYERLLSLPGIRLYGPERRASIISFNF 313
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 757598829 303 QMQNPALDAKFIEEAK---EQG----LLSLKGHKVAGGMRASIYNAMPLAGVQAL 350
Cdd:pfam00266 314 KGVHPHDVATLLDESGiavRSGhhcaQPLMVRLGLGGTVRASFYIYNTQEDVDRL 368
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05355 |
PRK05355 |
3-phosphoserine/phosphohydroxythreonine transaminase; |
1-362 |
0e+00 |
|
3-phosphoserine/phosphohydroxythreonine transaminase;
Pssm-ID: 235428 Cd Length: 360 Bit Score: 703.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 1 MSQVYNFSAGPAMLPVEVMRRAEQEFCNWQGLGVSVMEVSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAHF 80
Cdd:PRK05355 1 MMRVYNFSAGPAMLPEEVLEQAQQELLDWNGSGMSVMEISHRSKEFEAVAEEAEADLRELLNIPDNYKVLFLQGGASLQF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 81 ATIPMNLLGGKTTADYIVSGYWSESAAKEAAKYCKPNVIQIAEEkDGVVSLKPMSEWPLSDDAAYVHYCPNETIGGLALH 160
Cdd:PRK05355 81 AMVPMNLLGGGKKADYVDTGSWSKKAIKEAKKYGEVNVAASSED-DGFTYIPPLDEWQLSDDAAYVHYTSNETIDGTEFH 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 161 EEPDFpKDKIIVADYSSSILSKPIDVSRFGIIYAGAQKNIGPAGLTIVIIREDLLGKASPQTPSVFDYTLLAKHDSMFNT 240
Cdd:PRK05355 160 ELPDT-GDVPLVADMSSDILSRPIDVSKFGLIYAGAQKNIGPAGLTIVIVREDLLGRALPSIPSMLDYKTHADNDSMYNT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 241 PPTFAWYLSGMVFKWLKEQGGLQEMAKRNYEKSQLLYNAIDDSQFYINRVAVENRSWMNVPFQMQNPALDAKFIEEAKEQ 320
Cdd:PRK05355 239 PPTFAIYLAGLVFKWLKEQGGVAAMEKRNQEKAALLYDAIDSSDFYRNPVAPEDRSRMNVPFTLADEELDKKFLAEAKAA 318
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 757598829 321 GLLSLKGHKVAGGMRASIYNAMPLAGVQALVDFMADFERHNA 362
Cdd:PRK05355 319 GLVGLKGHRSVGGMRASIYNAMPLEGVQALVDFMKEFERRHG 360
|
|
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
2-361 |
0e+00 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 638.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 2 SQVYNFSAGPAMLPVEVMRRAEQEFCNWQGLGVSVMEVSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAHFA 81
Cdd:COG1932 1 MRVYNFSAGPAKLPEEVLEQAQAELLDWNGSGMSVMEMSHRSKPFKAIVEEAEADLRELLGIPDGYEVLFLQGGATAQFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 82 TIPMNLLGGKTTADYIVSGYWSESAAKEAAKYCKPNVIQIAEEkDGVVSLKPMSEWPLSDDAAYVHYCPNETIGGLALHE 161
Cdd:COG1932 81 MVPMNLLRGGKKADYLVTGEWSKKAIKEAKKYGEVNVVASSED-DNFGYIPKPEEWQLSPDADYVHYTSNETITGVEFHE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 162 EPDFPkDKIIVADYSSSILSKPIDVSRFGIIYAGAQKNIGPAGLTIVIIREDLLGKASPQTPSVFDYTLLAKHDSMFNTP 241
Cdd:COG1932 160 LPDVG-DVPLVADMSSDILSRPVDVSKFGLIYAGAQKNIGPAGLTVVIVRPDLLGRAERAIPSMLDYKTHADNDSMYNTP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 242 PTFAWYLSGMVFKWLKEQGGLQEMAKRNYEKSQLLYNAIDDSQFYINRVAVENRSWMNVPFQMQNPALDAKFIEEAKEQG 321
Cdd:COG1932 239 PTFAIYLAGLVLKWLKEQGGLAAMEKRNAEKAALLYDWIDASDFYTNPVDPEDRSRMNVTFDLADEELDAAFLAEAKAAG 318
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 757598829 322 LLSLKGHKVAGGMRASIYNAMPLAGVQALVDFMADFERHN 361
Cdd:COG1932 319 LVGLKGHRSVGGMRASIYNAMPLEGVEALVDFMDEFERRH 358
|
|
| PSAT_like |
cd00611 |
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP) ... |
5-359 |
0e+00 |
|
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as a dimer and catalyzes the conversion of phosphohydroxypyruvate to phosphoserine.
Pssm-ID: 99736 [Multi-domain] Cd Length: 355 Bit Score: 577.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 5 YNFSAGPAMLPVEVMRRAEQEFCNWQGLGVSVMEVSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAHFATIP 84
Cdd:cd00611 1 INFSAGPAALPEEVLEQAQKELLDFNGLGMSVMEMSHRSKDFEAIVNEAESDLRELLNIPDNYKVLFLQGGATGQFAAVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 85 MNLLGGKTTADYIVSGYWSESAAKEAAKYCKPNVIQIAEEKDGVVSLKPMSEWPLSDDAAYVHYCPNETIGGLALHEEPD 164
Cdd:cd00611 81 LNLLGDKGTADYVVTGAWSAKAAKEAKRYGGVVVIVAAKEEGKYTKIPDVETWDLAPDAAYVHYCSNETIHGVEFDEVPD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 165 FPkDKIIVADYSSSILSKPIDVSRFGIIYAGAQKNIGPAGLTIVIIREDLLGKASPQTPSVFDYTLLAKHDSMFNTPPTF 244
Cdd:cd00611 161 TG-GVPLVADMSSNILSRPIDVSKFGVIYAGAQKNLGPAGVTVVIVRKDLLGKARKITPSMLNYKTHADNNSLYNTPPTF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 245 AWYLSGMVFKWLKEQGGLQEMAKRNYEKSQLLYNAIDDSQ-FYINRVAVENRSWMNVPFQMQNPALDAKFIEEAKEQGLL 323
Cdd:cd00611 240 AIYMMGLVLKWLKEQGGVEAMEKRNRQKAQLLYDTIDNSNgFYRGPVDKRARSRMNVPFRLGKEELEKEFLKEAEAAGMI 319
|
330 340 350
....*....|....*....|....*....|....*.
gi 757598829 324 SLKGHKVAGGMRASIYNAMPLAGVQALVDFMADFER 359
Cdd:cd00611 320 GLKGHRSVGGIRASIYNALSLEGVQALADFMKEFQK 355
|
|
| serC_1 |
TIGR01364 |
phosphoserine aminotransferase; This model represents the common form of the phosphoserine ... |
12-361 |
0e+00 |
|
phosphoserine aminotransferase; This model represents the common form of the phosphoserine aminotransferase SerC. The phosphoserine aminotransferase of the archaeon Methanosarcina barkeri and putative phosphoserine aminotransferase of Mycobacterium tuberculosis are represented by separate models. All are members of the class V aminotransferases (pfam00266). [Amino acid biosynthesis, Serine family]
Pssm-ID: 130431 Cd Length: 349 Bit Score: 553.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 12 AMLPVEVMRRAEQEFCNWQGLGVSVMEVSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAHFATIPMNLLGGK 91
Cdd:TIGR01364 1 AALPEEVLEQAQKELLNFNGTGMSVMEISHRSKEFEAVANEAESDLRELLNIPDNYEVLFLQGGATGQFAAVPLNLLAEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 92 TTADYIVSGYWSESAAKEAAKYCKPNVIQIAEEKDgVVSLKPMSEWPLSDDAAYVHYCPNETIGGLALHEEPDFpKDKII 171
Cdd:TIGR01364 81 KVADYIVTGAWSKKAAKEAKKYGVVNVVASGKEGN-YTKIPDPSTWEISEDAAYVHYCANETIHGVEFRELPDV-KNAPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 172 VADYSSSILSKPIDVSRFGIIYAGAQKNIGPAGLTIVIIREDLLGKASPQTPSVFDYTLLAKHDSMFNTPPTFAWYLSGM 251
Cdd:TIGR01364 159 VADMSSNILSRPIDVSKFGLIYAGAQKNIGPAGLTVVIVRKDLLGRASRITPSMLNYKIHAENDSMYNTPPTFAIYVSGL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 252 VFKWLKEQGGLQEMAKRNYEKSQLLYNAIDDSQ-FYINRVAVENRSWMNVPFQMQNPALDAKFIEEAKEQGLLSLKGHKV 330
Cdd:TIGR01364 239 VFKWLKEQGGVKAIEKRNQAKAQLLYDTIDNSNgFYRNPVDPRNRSRMNVVFTLGNEELEKRFLKEAEERGLVSLKGHRS 318
|
330 340 350
....*....|....*....|....*....|.
gi 757598829 331 AGGMRASIYNAMPLAGVQALVDFMADFERHN 361
Cdd:TIGR01364 319 VGGMRASIYNAMPLEGVQALVDFMKEFQKKH 349
|
|
| PLN02452 |
PLN02452 |
phosphoserine transaminase |
4-362 |
0e+00 |
|
phosphoserine transaminase
Pssm-ID: 178071 Cd Length: 365 Bit Score: 512.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 4 VYNFSAGPAMLPVEVMRRAEQEFCNWQGLGVSVMEVSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAHFATI 83
Cdd:PLN02452 8 VFNFSAGPATLPANVLAKAQAELYNWEGSGMSVMEMSHRGKEFLSIIQKAEADLRELLDIPDNYEVLFLQGGASTQFAAI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 84 PMNLLGGKTTADYIVSGYWSESAAKEAAKYCKPNVIqiAEEKD-GVVSLKPMSEWPLSDDAAYVHYCPNETIGGLALHEE 162
Cdd:PLN02452 88 PLNLCKPGDKADFVVTGSWSKKAAKEAKKYCKTNVI--ASGKDeKYTKIPSVSEWELTPDAKFVHICANETIHGVEFKDY 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 163 PDFPkDKIIVADYSSSILSKPIDVSRFGIIYAGAQKNIGPAGLTIVIIREDLLGKASPQTPSVFDYTLLAKHDSMFNTPP 242
Cdd:PLN02452 166 PDVG-NVPLVADMSSNFLSKPVDVSKYGVIYAGAQKNVGPSGVTIVIIRKDLIGNARPITPGMLDYKIHAENDSLYNTPP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 243 TFAWYLSGMVFKWLKEQGGLQEMAKRNYEKSQLLYNAIDDSQ-FYINRVAVENRSWMNVPFQMQNPALDAKFIEEAKEQG 321
Cdd:PLN02452 245 CFGIYMCGLVFEDLLAQGGLKAMEKRNIRKADLLYDAIDESNgFYVCPVEKSVRSLMNVPFTLGGSELEAEFVKEAAKAG 324
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 757598829 322 LLSLKGHKVAGGMRASIYNAMPLAGVQALVDFMADFERHNA 362
Cdd:PLN02452 325 MVQLKGHRSVGGMRASIYNAMPLAGVEKLVAFMKDFQAKHA 365
|
|
| PRK12462 |
PRK12462 |
phosphoserine aminotransferase; Provisional |
6-362 |
4.56e-117 |
|
phosphoserine aminotransferase; Provisional
Pssm-ID: 183540 Cd Length: 364 Bit Score: 343.72 E-value: 4.56e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 6 NFSAGPAMLPVEVMRRAEQEFCNWQGLGVSVMEVSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAHFATIPM 85
Cdd:PRK12462 7 NFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAEADLRDLLGIPDEYGVVFLQGGSSLQFSMIPM 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 86 NLLGGKTT-ADYIVSGYWSESAAKEAAKYCKPNVIQiAEEKDGVVSLKPMSEWPLSDDAAYVHYCPNETIGGLALHEEPD 164
Cdd:PRK12462 87 NFSRPGAAaPEYVTTGYWSRKAIGEASRVAAMRVVW-DGAASGYRTLPSLAELDWDARAPFRHYVSNETVEGLQFPDAAG 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 165 FPkDKIIVADYSSSILSKPIDVSRFGIIYAGAQKNIGPAGLTIVIIREDLLGKASPQTPSVFDYTLLAKHDSMFNTPPTF 244
Cdd:PRK12462 166 LP-DSPLIADMSSDFMSRPFDVEAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNTPPVF 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 245 AWYLSGMVFKWLKEQ-GGLQEMAKRNYEKSQLLYNAIDDS-QFYINRVAVENRSWMNVPFQMQNPALDAKFIEEAKEQGL 322
Cdd:PRK12462 245 AIYVMALVLRWIRDEiGGVHAMRDINARKAAMLYATLDALnEVIDCHAHRAARSTMNVAFRFRQPRLDTLFKEQSTEAGF 324
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 757598829 323 LSLKGHKVAGGMRASIYNAMPLAGVQALVDFMADFERHNA 362
Cdd:PRK12462 325 CGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFAIRHA 364
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
4-350 |
1.81e-76 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 239.84 E-value: 1.81e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 4 VYNFSAGPAMLPVEVMRRAEQEFCNWQGLGVSvmEVSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAhFATI 83
Cdd:pfam00266 1 IYLDSAATTQKPQEVLDAIQEYYTDYNGNVHR--GVHTLGKEATQAYEEAREKVAEFINAPSNDEIIFTSGTTEA-INLV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 84 PMNL---LGGKTTADYIVSGYWSES-AAKEAAKYCKPNVIQIAEEKDGVVSLKPMsEWPLSDDAAYVHYCPNETIGGlAL 159
Cdd:pfam00266 78 ALSLgrsLKPGDEIVITEMEHHANLvPWQELAKRTGARVRVLPLDEDGLLDLDEL-EKLITPKTKLVAITHVSNVTG-TI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 160 HEEPDFPK-----DKIIVADYSSSILSKPIDVSRFGI--IYAGAQKNIGPAGLTIVIIREDLLGKASP--------QTPS 224
Cdd:pfam00266 156 QPVPEIGKlahqyGALVLVDAAQAIGHRPIDVQKLGVdfLAFSGHKLYGPTGIGVLYGRRDLLEKMPPllggggmiETVS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 225 vFDYTLLAKHDSMFN--TPPTFAWYLSGMVFKWLKEqGGLQEMAKRNYEKSQLLYNAIDDSQFYINRVAVENRSWMNVPF 302
Cdd:pfam00266 236 -LQESTFADAPWKFEagTPNIAGIIGLGAALEYLSE-IGLEAIEKHEHELAQYLYERLLSLPGIRLYGPERRASIISFNF 313
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 757598829 303 QMQNPALDAKFIEEAK---EQG----LLSLKGHKVAGGMRASIYNAMPLAGVQAL 350
Cdd:pfam00266 314 KGVHPHDVATLLDESGiavRSGhhcaQPLMVRLGLGGTVRASFYIYNTQEDVDRL 368
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
50-211 |
1.10e-20 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 87.82 E-value: 1.10e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 50 AKEAEQNLRDLLNvPSNYKILFCHGGARAhFATIPMNLLGGKTTADYIVSGYWSESAAKEAAKYCKPNVIQIAEEKDGVV 129
Cdd:cd01494 2 LEELEEKLARLLQ-PGNDKAVFVPSGTGA-NEAALLALLGPGDEVIVDANGHGSRYWVAAELAGAKPVPVPVDDAGYGGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 130 SLKPMSEWPLSDDAAYVHYCPNETIGGL--ALHE--EPDFPKDKIIVADYSSSILSKP-----IDVSRFGIIYAGAQKNI 200
Cdd:cd01494 80 DVAILEELKAKPNVALIVITPNTTSGGVlvPLKEirKIAKEYGILLLVDAASAGGASPapgvlIPEGGADVVTFSLHKNL 159
|
170
....*....|.
gi 757598829 201 GPAGLTIVIIR 211
Cdd:cd01494 160 GGEGGGVVIVK 170
|
|
| AGAT_like |
cd06451 |
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate ... |
7-332 |
2.74e-12 |
|
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), serine-glyoxylate aminotransferase (SGAT), and 3-hydroxykynurenine transaminase (HKT). AGAT is a homodimeric protein, which catalyses the transamination of glyoxylate to glycine, and SGAT converts serine and glyoxylate to hydroxypyruvate and glycine. HKT catalyzes the PLP-dependent transamination of 3-hydroxykynurenine, a potentially toxic metabolite of the kynurenine pathway.
Pssm-ID: 99744 [Multi-domain] Cd Length: 356 Bit Score: 66.93 E-value: 2.74e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 7 FSAGPAMLPVEVMrraeqefcnwQGLGVSVMevSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAHFATIpMN 86
Cdd:cd06451 3 LIPGPSNVPPRVL----------KAMNRPML--GHRSPEFLALMDEILEGLRYVFQTENGLTFLLSGSGTGAMEAAL-SN 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 87 LL--GGKTTAdyIVSGYWSESAAKEAAKYcKPNVIQIAEEKDGVVSLKPMSEWPLSDDAAYVHYCPNETIGGlALHEEPD 164
Cdd:cd06451 70 LLepGDKVLV--GVNGVFGDRWADMAERY-GADVDVVEKPWGEAVSPEEIAEALEQHDIKAVTLTHNETSTG-VLNPLEG 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 165 FPK-----DKIIVADYSSSILSKPIDVSRFGI--IYAGAQKNIG-PAGLTIVIIREDLLGKASPQTPSV---FDYTLLAK 233
Cdd:cd06451 146 IGAlakkhDALLIVDAVSSLGGEPFRMDEWGVdvAYTGSQKALGaPPGLGPIAFSERALERIKKKTKPKgfyFDLLLLLK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 234 H----DSMFNTPPTFAWYLSGMVFKWLKEQgGLQEMAKRNYEKSQLLYNAIDDSQFyinRVAVENRSWMN-VPFQMQNPA 308
Cdd:cd06451 226 YwgegYSYPHTPPVNLLYALREALDLILEE-GLENRWARHRRLAKALREGLEALGL---KLLAKPELRSPtVTAVLVPEG 301
|
330 340
....*....|....*....|....*..
gi 757598829 309 LDAK-FIEEAKEQGLLSLKG--HKVAG 332
Cdd:cd06451 302 VDGDeVVRRLMKRYNIEIAGglGPTAG 328
|
|
| PRK03080 |
PRK03080 |
phosphoserine transaminase; |
6-278 |
1.37e-07 |
|
phosphoserine transaminase;
Pssm-ID: 235103 Cd Length: 378 Bit Score: 52.88 E-value: 1.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 6 NFSAGPAmlpveVMRRAEQefcnWQGLGVSVMEVSHRGKEFVEVAKEAEQNLRDLLNVPSNYKILFCHGGARAHFATIPM 85
Cdd:PRK03080 15 RFSSGPC-----KKRPGWQ----LEALADALLGRSHRQKPVKALLKRVIEGTRELLSLPEGYEVGIVPGSDTGAWEMALW 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 86 NLLGGKtTADYIVSGYWSE---SAAKEAAKYCKPNVIQiAEEkdGvvSLKPMSEWPLSDDAAYVHycpNETIGGLALhee 162
Cdd:PRK03080 86 SLLGAR-RVDHLAWESFGSkwaTDVVKQLKLEDPRVLE-ADY--G--SLPDLSAVDFDRDVVFTW---NGTTTGVRV--- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757598829 163 PDF---PKDK--IIVADYSSSILSKPIDVSRFGIIYAGAQKNIG-PAGLTIVII------REDLLGKASPqTPSVFDYTL 230
Cdd:PRK03080 154 PVArwiGADRegLTICDATSAAFALPLDWSKLDVYTFSWQKVLGgEGGHGMAILspraveRLESYTPARP-IPKFFRLTK 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 757598829 231 LAK------HDSMFNTPP--TFAWYLSGMvfKWLKEQGGLQEMAKRNYEKSQLLYN 278
Cdd:PRK03080 233 GGKaiensfKGQTINTPSmlTVEDYLDQL--DWANSIGGLDALIARTAANASVLYD 286
|
|
| |
