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Conserved domains on  [gi|757782245|ref|WP_043000829|]
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MULTISPECIES: ferredoxin-like protein [Citrobacter]

Protein Classification

ferredoxin-like protein YdhY( domain architecture ID 11484518)

ferredoxin-like protein YdhY is up-regulated by the oxygen-responsive transcription factor FNR under anaerobic conditions and repressed in the presence of nitrate or nitrite via the two-component systems NarXL and NarPQ, respectively

Gene Ontology:  GO:0046872|GO:0051539

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK09898 PRK09898
ferredoxin-like protein;
1-208 1.00e-129

ferredoxin-like protein;


:

Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 363.39  E-value: 1.00e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245   1 MNQVDRPLLDTGLTRLEFLRISGKGLAGLTIAPALLSLFGCKQEDIDSGTVGLISTPKGVLVTQRARCTGCHRCEISCTN 80
Cdd:PRK09898   1 MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  81 YNDGAVGTFFSRIKIHRHYFFGDKGPGSGGGLYGDLNYTPDTCRQCKDPQCMKVCPIGAITWSQEDGCIAVDHRRCIGCS 160
Cdd:PRK09898  81 FNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCS 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 757782245 161 ACTTACPWMMATVNTETKKSSKCVLCGECASACPTGALKIIEWKDITV 208
Cdd:PRK09898 161 ACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV 208
 
Name Accession Description Interval E-value
PRK09898 PRK09898
ferredoxin-like protein;
1-208 1.00e-129

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 363.39  E-value: 1.00e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245   1 MNQVDRPLLDTGLTRLEFLRISGKGLAGLTIAPALLSLFGCKQEDIDSGTVGLISTPKGVLVTQRARCTGCHRCEISCTN 80
Cdd:PRK09898   1 MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  81 YNDGAVGTFFSRIKIHRHYFFGDKGPGSGGGLYGDLNYTPDTCRQCKDPQCMKVCPIGAITWSQEDGCIAVDHRRCIGCS 160
Cdd:PRK09898  81 FNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCS 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 757782245 161 ACTTACPWMMATVNTETKKSSKCVLCGECASACPTGALKIIEWKDITV 208
Cdd:PRK09898 161 ACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV 208
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 61-201 1.09e-44

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 145.03  E-value: 1.09e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  61 LVTQRARCTGCHRCEISCTNYNDGAVGTFFSRIKIHRHYFfgdkgpgsggglygDLNYTPDTCRQCKDPQCMKVCPIGAI 140
Cdd:cd10550    1 LVVDPEKCTGCRTCELACSLKHEGVFNPSLSRIRVVRFEP--------------EGLDVPVVCRQCEDAPCVEACPVGAI 66

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757782245 141 TWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCG---ECASACPTGALKII 201
Cdd:cd10550   67 SRDEETGAVVVDEDKCIGCGMCVEACPFGAIRVDPETGKAIKCDLCGgdpACVKVCPTGALEFV 130
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 67-206 3.52e-34

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 120.05  E-value: 3.52e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  67 RCTGCHRCEISCTNYNDGAVGTFFSRIKIHRHYFFGDKgpgsggglygDLNYTPDTCRQCKDPQCMKVCPIGAItWSQED 146
Cdd:COG0437   14 KCIGCRACVVACKEENNLPVGVTWRRVRRYEEGEFPNV----------EWLFVPVLCNHCDDPPCVKVCPTGAT-YKRED 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757782245 147 GCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGE---------CASACPTGALKIIEWKDI 206
Cdd:COG0437   83 GIVLVDYDKCIGCRYCVAACPYGAPRFNPETGVVEKCTFCADrldegllpaCVEACPTGALVFGDLDDP 151
Fer4_11 pfam13247
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 115-198 9.11e-16

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 404184 [Multi-domain]  Cd Length: 99  Bit Score: 69.58  E-value: 9.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  115 DLNYTPDTCRQCKDPQCMKVCPIGAITWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGE------ 188
Cdd:pfam13247   2 DWLFFPEQCRHCLNPPCKASCPVGAIYKDEETGAVLLDEKTCRGWRECVSACPYNIPRYNDETGKAEKCDMCYDrveagl 81

                          90
                  ....*....|...
gi 757782245  189 ---CASACPTGAL 198
Cdd:pfam13247  82 lpaCVQTCPTGAM 94
sulfite_red_C TIGR02912
sulfite reductase, subunit C; Members of this protein family include the C subunit, one of ...
 135-197 7.35e-07

sulfite reductase, subunit C; Members of this protein family include the C subunit, one of three subunits, of the anaerobic sulfite reductase of Salmonella, and close homologs from various Clostridum species, where the three-gene neighborhood is preserved. Two such gene clusters are found in Clostridium perfringens, but it may be that these sets of genes correspond to the distinct assimilatory and dissimilatory forms as seen in Clostridium pasteurianum. Note that any one of these enzymes may have secondary substates such as NH2OH, SeO3(2-), and SO3(2-). Heterologous expression of the anaerobic sulfite reductase of Salmonella confers on Escherichia coli the ability to produce hydrogen sulfide gas from sulfite. [Central intermediary metabolism, Sulfur metabolism]


Pssm-ID: 131958 [Multi-domain]  Cd Length: 314  Bit Score: 48.32  E-value: 7.35e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757782245  135 CPIGAITWSQED-GCIAV-----DHRRCIGCSACTTACP----WMMATVNTET-KKSSKCVLCGECASACPTGA 197
Cdd:TIGR02912 144 CPNDCAKARMHDfGIIGMtepqyDADRCIGCGACVKVCKkkavGALSFENYKVvRDHSKCIGCGECVLKCPTGA 217
 
Name Accession Description Interval E-value
PRK09898 PRK09898
ferredoxin-like protein;
1-208 1.00e-129

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 363.39  E-value: 1.00e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245   1 MNQVDRPLLDTGLTRLEFLRISGKGLAGLTIAPALLSLFGCKQEDIDSGTVGLISTPKGVLVTQRARCTGCHRCEISCTN 80
Cdd:PRK09898   1 MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  81 YNDGAVGTFFSRIKIHRHYFFGDKGPGSGGGLYGDLNYTPDTCRQCKDPQCMKVCPIGAITWSQEDGCIAVDHRRCIGCS 160
Cdd:PRK09898  81 FNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCS 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 757782245 161 ACTTACPWMMATVNTETKKSSKCVLCGECASACPTGALKIIEWKDITV 208
Cdd:PRK09898 161 ACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV 208
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 61-201 1.09e-44

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 145.03  E-value: 1.09e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  61 LVTQRARCTGCHRCEISCTNYNDGAVGTFFSRIKIHRHYFfgdkgpgsggglygDLNYTPDTCRQCKDPQCMKVCPIGAI 140
Cdd:cd10550    1 LVVDPEKCTGCRTCELACSLKHEGVFNPSLSRIRVVRFEP--------------EGLDVPVVCRQCEDAPCVEACPVGAI 66

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757782245 141 TWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCG---ECASACPTGALKII 201
Cdd:cd10550   67 SRDEETGAVVVDEDKCIGCGMCVEACPFGAIRVDPETGKAIKCDLCGgdpACVKVCPTGALEFV 130
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 67-206 3.52e-34

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 120.05  E-value: 3.52e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  67 RCTGCHRCEISCTNYNDGAVGTFFSRIKIHRHYFFGDKgpgsggglygDLNYTPDTCRQCKDPQCMKVCPIGAItWSQED 146
Cdd:COG0437   14 KCIGCRACVVACKEENNLPVGVTWRRVRRYEEGEFPNV----------EWLFVPVLCNHCDDPPCVKVCPTGAT-YKRED 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757782245 147 GCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGE---------CASACPTGALKIIEWKDI 206
Cdd:COG0437   83 GIVLVDYDKCIGCRYCVAACPYGAPRFNPETGVVEKCTFCADrldegllpaCVEACPTGALVFGDLDDP 151
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 66-200 1.15e-29

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 106.70  E-value: 1.15e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  66 ARCTGCHRCEISCTNYNDGAVGTFFSRIKIHRhyffgdkgpgsggGLYGDLNYTPDTCRQCKDPQCMKVCPIGAItWSQE 145
Cdd:cd04410    6 DRCIGCGTCEVACKQEHGLRPGPDWSRIKVIE-------------GGGLERAFLPVSCMHCEDPPCVKACPTGAI-YKDE 71

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757782245 146 DGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGE---------CASACPTGALKI 200
Cdd:cd04410   72 DGIVLIDEDKCIGCGSCVEACPYGAIVFDPEPGKAVKCDLCGDrldeglepaCVKACPTGALTF 135
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 67-201 8.24e-29

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 104.57  E-value: 8.24e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  67 RCTGCHRCEISCTNYNDGAVGTFFSRIKIHRHYFFGDKGPGsggglygdlnYTPDTCRQCKDPQCMKVCPIGAITwSQED 146
Cdd:cd16371    8 RCIGCKACEIACKDKNDLPPGVNWRRVYEYEGGEFPEVFAY----------FLSMSCNHCENPACVKVCPTGAIT-KRED 76

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757782245 147 GCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLC------GE---CASACPTGALKII 201
Cdd:cd16371   77 GIVVVDQDKCIGCGYCVWACPYGAPQYNPETGKMDKCDMCvdrldeGEkpaCVAACPTRALDFG 140
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
66-202 1.35e-26

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 98.96  E-value: 1.35e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  66 ARCTGCHRCEISC-TNYNDGAVGTFFSRIKIHRHYFFgdkgpgsggglygdlnYTPDTCRQCKDPQCMKVCPIGAITwsQ 144
Cdd:COG1142   10 EKCIGCRTCEAACaVAHEGEEGEPFLPRIRVVRKAGV----------------SAPVQCRHCEDAPCAEVCPVGAIT--R 71

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757782245 145 EDGCIAVDHRRCIGCSACTTACPWMMATVNTET--KKSSKCVLCGE------CASACPTGALKIIE 202
Cdd:COG1142   72 DDGAVVVDEEKCIGCGLCVLACPFGAITMVGEKsrAVAVKCDLCGGreggpaCVEACPTGALRLVD 137
CooF_like cd10563
CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the ...
 65-201 1.13e-23

CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the iron-sulfur subunit of carbon monoxide dehydrogenase (CODH), found in anaerobic bacteria and archaea. Carbon monoxide dehydrogenase is a key enzyme for carbon monoxide (CO) metabolism, where CooF is the proposed mediator of electron transfer between CODH and the CO-induced hydrogenase, catalyzing the reaction that uses CO as a single carbon and energy source, and producing only H2 and CO2. The ion-sulfur subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons in the protein complex during reaction.


Pssm-ID: 319885 [Multi-domain]  Cd Length: 140  Bit Score: 91.55  E-value: 1.13e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  65 RARCTGCHRCEISCTNYNDGAVGTFF---------SRIKIHRhyffgdkgpgsggglyGDLNYTPDTCRQCKDPQCMKVC 135
Cdd:cd10563    6 EEKCLGCKLCEVACAVAHSKSKDLIKaklekerprPRIRVEE----------------SGGRSFPLQCRHCDEPPCVKAC 69

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757782245 136 PIGAITWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGE-----CASACPTGALKII 201
Cdd:cd10563   70 MSGAMHKDPETGIVIHDEEKCVGCWMCVMVCPYGAIRPDKERKVALKCDLCPDretpaCVEACPTGALVLE 140
PhsB_like cd10553
uncharacterized beta subfamily of DMSO Reductase similar to Desulfonauticus sp PhsB; This ...
 60-199 1.44e-23

uncharacterized beta subfamily of DMSO Reductase similar to Desulfonauticus sp PhsB; This family includes beta FeS subunits of anaerobic DMSO reductase (DMSOR) superfamily that have yet to be characterized. DMSOR consists of a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and the tungsten-containing formate dehydrogenase (FDH-T). Examples of heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319875 [Multi-domain]  Cd Length: 146  Bit Score: 91.27  E-value: 1.44e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  60 VLVTQRARCTGCHRCEISCTNYNDGAVGTFFSRIkihrhyfFGDKGPGSGGGLYGDLNYTPdtCRQCKDPQCMKVCPIGA 139
Cdd:cd10553    4 YLYHDSKRCIGCLACEVHCKVKNNLPVGPRLCRI-------FAVGPKMVGGKPRLKFVYMS--CFHCENPWCVKACPTGA 74

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757782245 140 ITWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGE---------CASACPTGALK 199
Cdd:cd10553   75 MQKREKDGIVYVDQELCIGCKACIEACPWGIPQWNPATGKVVKCDYCMDridqglkpaCVTGCTTHALS 143
PsrB cd10551
polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...
 67-198 5.97e-23

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.


Pssm-ID: 319873 [Multi-domain]  Cd Length: 185  Bit Score: 91.05  E-value: 5.97e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  67 RCTGCHRCEISCTNYNDGAVGTFFSRIKIHRHYFFGDKgpgsggglygDLNYTPDTCRQCKDPQCMKVCPIGAiTWSQED 146
Cdd:cd10551    7 KCIGCGACVVACKAENNVPPGVFRNRVLEYEVGEYPNV----------KRTFLPVLCNHCENPPCVKVCPTGA-TYKRED 75

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757782245 147 GCIAVDHRRCIGCSACTTACP------------WMMATVNTETKKSSKCVLCGE---------CASACPTGAL 198
Cdd:cd10551   76 GIVLVDYDKCIGCRYCMAACPygaryfnpeephEFGEVPVRPKGVVEKCTFCYHrldegllpaCVEACPTGAR 148
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 66-201 1.48e-22

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 88.86  E-value: 1.48e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  66 ARCTGCHRCEISC----TNYNDGAVGT----FFSRIKIHRHYFFGdkgpgsggglygdlnyTPDTCRQCKDPQCMKVCPI 137
Cdd:cd10554    7 DKCIGCRTCEVACaaahSGKGIFEAGTdglpFLPRLRVVKTGEVT----------------APVQCRQCEDAPCANVCPV 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 138 GAItwSQEDGCIAVDHRRCIGCSACTTACPW-----------MMATVNTETKKSSKCVLCGE------CASACPTGALKI 200
Cdd:cd10554   71 GAI--SQEDGVVQVDEERCIGCKLCVLACPFgaiemapttvpGVDWERGPRAVAVKCDLCAGreggpaCVEACPTKALTL 148


                 .
gi 757782245 201 I 201
Cdd:cd10554  149 V 149
FDH_beta_like cd16366
beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family ...
 67-199 9.31e-21

beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family contains beta FeS subunits of several dehydrogenases in the DMSO reductase superfamily, including formate dehydrogenase N (FDH-N), tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N is a major component of nitrate respiration of Escherichia coli; it catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate to a cytochrome. W-FDH contains a tungsten instead of molybdenum at the catalytic center and seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate.


Pssm-ID: 319888 [Multi-domain]  Cd Length: 156  Bit Score: 84.37  E-value: 9.31e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  67 RCTGCHRCEISCTNYND--GAVGTFFSRIKIHRH-----YFFGDKGPGSGGGLYGDLNYTPDTCRQCKDPQCMKVCPIGA 139
Cdd:cd16366    7 RCTGCRACQVACKQWNGlpAEKTEFTGSYQNPPDltahtWTLVRFYEVEKPGGDLSWLFRKDQCMHCTDAGCLAACPTGA 86

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757782245 140 ITwSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGE---------CASACPTGALK 199
Cdd:cd16366   87 II-RTETGTVVVDPETCIGCGYCVNACPFDIPRFDEETGRVAKCTLCYDrisnglqpaCVKTCPTGALT 154
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 66-199 1.22e-20

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 84.28  E-value: 1.22e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  66 ARCTGCHRCEISCTNYND-GAVGTFFS---------------RIKIHRHYffgdkgpgsGGGLYGDLNYTPDTCRQCKDP 129
Cdd:cd10562    6 SKCTACRGCQVACKQWNQlPAEKTPFTgsyqnppdltpntwtLIRFYEHE---------EDNGGIRWLFRKRQCMHCTDA 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757782245 130 QCMKVCPIGAITWSqEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGE---------CASACPTGALK 199
Cdd:cd10562   77 ACVKVCPTGALYKT-ENGAVVVDEDKCIGCGYCVAACPFDVPRYDETTNKITKCTLCFDriengmqpaCVKTCPTGALT 154
DMSOR_beta_like cd16374
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 67-206 1.27e-20

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319896 [Multi-domain]  Cd Length: 139  Bit Score: 83.48  E-value: 1.27e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  67 RCTGCHRCEISCTNYNDGAvgtffSRIKIHRhyffgdkgpgsggglYGDLNYTPDTCRQCKDPQCMKVCPIGAITwSQED 146
Cdd:cd16374    7 RCIGCRACEIACAREHSGK-----PRISVEV---------------VEDLASVPVRCRHCEDAPCMEVCPTGAIY-RDED 65

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757782245 147 GCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGE---------CASACPTGALKIIEWKDI 206
Cdd:cd16374   66 GAVLVDPDKCIGCGMCAMACPFGVPRFDPSLKVAVKCDLCIDrrregklpaCVEACPTGALKFGDIEEL 134
PRK14993 PRK14993
tetrathionate reductase subunit TtrB;
20-205 8.59e-20

tetrathionate reductase subunit TtrB;


Pssm-ID: 184955 [Multi-domain]  Cd Length: 244  Bit Score: 84.16  E-value: 8.59e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  20 RISGKGLAGLTIAPALLSLFGCKQEDIDSGTVGLISTPKGVLVTQRaRCTGCHRCEISCTNYNDGAVGTFFSRIkihRHY 99
Cdd:PRK14993   6 RQFLQQLGVLTAGASLVPLAEAKFPFSPERHEGSPRHRYAMLIDLR-RCIGCQSCTVSCTIENQTPQGAFRTTV---NQY 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 100 FFGDKGPGSGGGLYGdlnytPDTCRQCKDPQCMKVCPIGAiTWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKK 179
Cdd:PRK14993  82 QVQREGSQEVTNVLL-----PRLCNHCDNPPCVPVCPVQA-TFQREDGIVVVDNKRCVGCAYCVQACPYDARFINHETQT 155

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 757782245 180 SSKCVLCGE---------CASACPTGALKIIEWKD 205
Cdd:PRK14993 156 ADKCTFCVHrleagllpaCVESCVGGARIIGDIKD 190
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 67-201 2.13e-18

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 82.49  E-value: 2.13e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  67 RCTGCHRCEISCT-NYNDG----AVGTFFSRIKIHRHyffgdkgpgsggglygDLNYTPDTCRQCKDPQCMKVCPIGAIt 141
Cdd:PRK12769  11 QCLGCHACEIACVmAHNDEqhvlSQHHFHPRITVIKH----------------QQQRSAVTCHHCEDAPCARSCPNGAI- 73

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757782245 142 wSQEDGCIAVDHRRCIGCSACTTACPW-MMATVNTETKKSS------KCVLCGE------CASACPTGALKII 201
Cdd:PRK12769  74 -SHVDDSIQVNQQKCIGCKSCVVACPFgTMQIVLTPVAAGKvkatahKCDLCAGrengpaCVENCPADALQLV 145
FDH-N cd10558
The beta FeS subunit of formate dehydrogenase-N (FDH-N); This subfamily contains beta FeS ...
 66-207 7.00e-18

The beta FeS subunit of formate dehydrogenase-N (FDH-N); This subfamily contains beta FeS subunit of formate dehydrogenase-N (FDH-N), a member of the DMSO reductase family. FDH-N is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. Thus, FDH-N is a major component of nitrate respiration of Escherichia coli. This integral membrane enzyme forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups.


Pssm-ID: 319880 [Multi-domain]  Cd Length: 208  Bit Score: 78.20  E-value: 7.00e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  66 ARCTGCHRCEISCTNYND--GAVGTFFSRIKIHR----HYFFGDKGPGSGGGLYGDLNYTPDTCRQCKDPQCMKVCPIGA 139
Cdd:cd10558    7 SKCIGCKACQVACKEWNDlrAEVGHNVGTYQNPAdlspETWTLMKFREVEDNGKLEWLIRKDGCMHCADPGCLKACPSPG 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757782245 140 ITWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGE---------CASACPTGALKIIEWKDIT 207
Cdd:cd10558   87 AIVQYANGIVDFQSDKCIGCGYCIKGCPFDIPRISKDDNKMYKCTLCSDrvsvglepaCVKTCPTGALHFGTKEDML 163
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 61-206 1.32e-17

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 80.45  E-value: 1.32e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  61 LVTQRARCTGCHRCEISC-TNYNDGAVGTFFSRIKIHRHYFFGDkgpgsggglygdLNYTPDTCRQCKDPQCMKVCPIGA 139
Cdd:PRK12809   5 IAAEAAECIGCHACEIACaVAHNQENWPLSHSDFRPRIHVVGKG------------QAANPVACHHCNNAPCVTACPVNA 72

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757782245 140 ITWSQEDgcIAVDHRRCIGCSACTTACPW----MMATVntetkkSSKCVLCGE-------CASACPTGALKIIEWKDI 206
Cdd:PRK12809  73 LTFQSDS--VQLDEQKCIGCKRCAIACPFgvveMVDTI------AQKCDLCNQrssgtqaCIEVCPTQALRLMDDKGL 142
DMSOR_beta_like cd16369
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 67-198 1.78e-17

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319891 [Multi-domain]  Cd Length: 172  Bit Score: 76.27  E-value: 1.78e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  67 RCTGCHRCEISCTNyndgaVGTFFSRIKIHRHYFfgdkgpgsggGLYGDLNYTPDTCRQCKDPQCMKVCPIGAITWSQED 146
Cdd:cd16369   10 RCIGCRACVAACRE-----CGTHRGKSMIHVDYI----------DRGESTQTAPTVCMHCEDPTCAEVCPADAIKVTEDG 74

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757782245 147 GCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGE---------CASACPTGAL 198
Cdd:cd16369   75 VVQSALKPRCIGCSNCVNACPFGVPKYDEERNLMMKCDMCYDrtsvgkapmCASVCPSGAL 135
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 60-202 3.39e-17

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 74.29  E-value: 3.39e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  60 VLVTQRARCTGCHRCEISCTNyndgavgTFF-------SRIKIhrhyffgdkgpgsgggLYGDLNYTPDTCRQCKdpQCM 132
Cdd:cd16372    2 LLVTDPEKCIGCLQCEEACSK-------TFFkeedrekSCIRI----------------TETEGGYAINVCNQCG--ECI 56

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 133 KVCPIGAITWSQEdGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGECASACPTGALKIIE 202
Cdd:cd16372   57 DVCPTGAITRDAN-GVVMINKKLCVGCLMCVGFCPEGAMFKHEDYPEPFKCIACGICVKACPTGALELVE 125
FDH-O_like cd10560
beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes ...
 68-199 4.45e-17

beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes beta subunit of formate dehydrogenase family O (FDH-O), which is highly homologous to formate dehydrogenase N (FDH-N), a member of the DMSO reductase family. In E. coli three formate dehydrogenases are synthesized that are capable of oxidizing formate; Fdh-H, couples formate disproportionation to hydrogen and CO2, and is part of the cytoplasmically oriented formate hydrogenlyase complex, while FDH-N and FDH-O indicate their respective induction after growth with nitrate and oxygen. Little is known about FDH-O, although it shows formate oxidase activity during aerobic growth and is also synthesized during nitrate respiration, similar to FDH-N.


Pssm-ID: 319882 [Multi-domain]  Cd Length: 225  Bit Score: 76.27  E-value: 4.45e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  68 CTGCHRCEISCTNYND-GAVGTFFSRI----------KIHRHYFFGDKGPGSGGGLYGDLN---YTPDTCRQCKDPQCMK 133
Cdd:cd10560    9 CIGCKACEVACKQWNQlPADGYDFSGMsydntgdlsaSTWRHVKFIERPTEDGPANEGGDLqwlFMSDVCKHCTDAGCLE 88

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757782245 134 VCPIGAITWSqEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGE---------CASACPTGALK 199
Cdd:cd10560   89 ACPTGAIFRT-EFGTVYIQPDICNGCGYCVAACPFGVIDRNEETGRAHKCTLCYDrlkdglepaCAKACPTGSIQ 162
DMSOR_beta_like cd16367
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 60-199 7.79e-17

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319889 [Multi-domain]  Cd Length: 138  Bit Score: 73.50  E-value: 7.79e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  60 VLVTQRARCTGCHRCEISCTNYNDGA-----VGTFFSRIKIhrhyffgdkgpgsggglygdlnytPDTCRQCKDPQCMKV 134
Cdd:cd16367   13 LLVIDLDRCIRCDNCEKACADTHDGHsrldrNGLRFGNLLV------------------------PTACRHCVDPVCMIG 68

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 135 CPIGAITWSqEDGCIAVDHrRCIGCSACTTACPWMmatvNTETKKSSKCVLCGE-----CASACPTGALK 199
Cdd:cd16367   69 CPTGAIHRD-DGGEVVISD-ACCGCGNCASACPYG----AIQMVRAVKCDLCAGyagpaCVSACPTGAAI 132
TH_beta_N cd10552
N-terminal FeS domain of pyrogallol-phloroglucinol transhydroxylase (TH), beta subunit; This ...
 66-205 2.49e-16

N-terminal FeS domain of pyrogallol-phloroglucinol transhydroxylase (TH), beta subunit; This family includes the beta subunit of pyrogallol-phloroglucinol transhydroxylase (TH), a cytoplasmic molybdenum (Mo) enzyme from anaerobic microorganisms like Pelobacter acidigallici and Desulfitobacterium hafniense which catalyzes the conversion of pyrogallol to phloroglucinol, an important building block of plant polymers. TH belongs to the DMSO reductase (DMSOR) family; it is a heterodimer consisting of a large alpha catalytic subunit and a small beta FeS subunit. The beta subunit has two domains with the N-terminal domain containing three [4Fe-4S] centers and a seven-stranded, mainly antiparallel beta-barrel domain. In the anaerobic bacterium Pelobacter acidigallici, gallic acid, pyrogallol, phloroglucinol, or phloroglucinol carboxylic acid are fermented to three molecules of acetate (plus CO2), and TH is the key enzyme in the fermentation pathway, which converts pyrogallol to phloroglucinol in the absence of O2.


Pssm-ID: 319874 [Multi-domain]  Cd Length: 186  Bit Score: 73.51  E-value: 2.49e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  66 ARCTGCHRCEISCtnyNDGAVGTFFSRIK----IHRHYFFGDKGPGSGGGLYGDLNYTPDTCRQCKDPQCMKVCPIGAIT 141
Cdd:cd10552    6 AKCNGCYNCFLAC---KDEHVGNDWPGYAapqpRHGHFWMRILRRERGQYPKVDVAYLPVPCNHCDNAPCIKAAKDGAVY 82

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757782245 142 wSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCG----------ECASACPTGALKIIEWKD 205
Cdd:cd10552   83 -KRDDGIVIIDPEKAKGQKQLVDACPYGAIYWNEELQVPQKCTFCAhllddgwkepRCVQACPTGALRFGKLED 155
NarH_like cd16365
beta FeS subunits DMSOR NarH-like family; This subfamily contains beta FeS subunits of several ...
 67-194 7.98e-16

beta FeS subunits DMSOR NarH-like family; This subfamily contains beta FeS subunits of several DMSO reductase superfamily, including nitrate reductase A, ethylbenzene dehydrogenase and selenate reductase. DMSO Reductase (DMSOR) family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. . The beta subunits of DMSOR contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system. Nitrate reductase A contains three subunits (the catalytic subunit NarG, the catalytic subunit NarH with four [Fe-S] clusters, and integral membrane subunit NarI) and often forms a respiratory chain with the formate dehydrogenase via the lipid soluble quinol pool. Ethylbenzene dehydrogenase oxidizes the hydrocarbon ethylbenzene to (S)-1-phenylethanol. Selenate reductase catalyzes reduction of selenate to selenite in bacterial species that can obtain energy by respiring anaerobically with selenate as the terminal electron acceptor.


Pssm-ID: 319887 [Multi-domain]  Cd Length: 201  Bit Score: 72.61  E-value: 7.98e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  67 RCTGCHRCEISCTN---YNDGAVGTFFSRIKIHRHYFFGDKGPGSGGGLYGDLN---YTPDTCRQCKDPQCMKVCPIGAI 140
Cdd:cd16365   11 KCIGCQTCTVACKNawtYRKGQEYMWWNNVETKPGGGYPQDWEVKTIDNGGNTRfffYLQRLCNHCTNPACLAACPRGAI 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757782245 141 TWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLC---------GECASACP 194
Cdd:cd16365   91 YKREEDGIVLIDQKRCRGYRKCVEQCPYKKIYFNGLSRVSEKCIACyprieggdpTRCMSACV 153
Fer4_11 pfam13247
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 115-198 9.11e-16

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 404184 [Multi-domain]  Cd Length: 99  Bit Score: 69.58  E-value: 9.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  115 DLNYTPDTCRQCKDPQCMKVCPIGAITWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGE------ 188
Cdd:pfam13247   2 DWLFFPEQCRHCLNPPCKASCPVGAIYKDEETGAVLLDEKTCRGWRECVSACPYNIPRYNDETGKAEKCDMCYDrveagl 81

                          90
                  ....*....|...
gi 757782245  189 ---CASACPTGAL 198
Cdd:pfam13247  82 lpaCVQTCPTGAM 94
HybA_like cd10561
the FeS subunit of hydrogenase 2; This subfamily includes the beta-subunit of hydrogenase 2 ...
 67-199 2.79e-15

the FeS subunit of hydrogenase 2; This subfamily includes the beta-subunit of hydrogenase 2 (Hyd-2), an enzyme that catalyzes the reversible oxidation of H2 to protons and electrons. Hyd-2 is membrane-associated and forms an unusual heterotetrameric [NiFe]-hydrogenase in that it lacks the typical cytochrome b membrane anchor subunit that transfers electrons to the quinone pool. The electron transfer subunit of Hyd-2 (HybA) which is predicted to contain four iron-sulfur clusters, is essential for electron transfer from Hyd-2 to menaquinone/demethylmenaquinone (MQ/DMQ) to couple hydrogen oxidation to fumarate reduction.


Pssm-ID: 319883 [Multi-domain]  Cd Length: 196  Bit Score: 70.70  E-value: 2.79e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  67 RCTGCHRCEISCTNYND-GAVGTFFSRIKIHR----HYFFGDKGPGSGGGLYGDLNYTPDTCRQCKDPQCMKVCPIGAIT 141
Cdd:cd10561    8 RCIGCRACEVACKEWNGlPAEDTAFGPGWDNPrdlsAKTYTVIKRYEVETGGKGFVFVKRQCMHCLDPACVSACPVGALR 87

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757782245 142 wSQEDGCIAVDHRRCIGCSACTTACPWMMATV--NTETKKSSKCVLCGE---------CASACPTGALK 199
Cdd:cd10561   88 -KTPEGPVTYDEDKCIGCRYCMVACPFNIPKYewDSANPKIRKCTMCYDrlkegkqpaCVEACPTGALL 155
NarH_beta-like cd10557
beta subunit of nitrate reductase A (NarH) and similar proteins; This subfamily includes ...
 118-186 1.42e-14

beta subunit of nitrate reductase A (NarH) and similar proteins; This subfamily includes nitrate reductase A, a member of the DMSO reductase family. The respiratory nitrate reductase complex (NarGHI) from E. coli is a heterotrimer, with the catalytic subunit (NarG) with a molybdo-bis (molybdopterin guanine dinucleotide) cofactor and an [Fe-S] cluster, the electron transfer subunit (NarH) with four [Fe-S] clusters, and the integral membrane subunit (NarI) with two b-type hemes. Nitrate reductase A often forms a respiratory chain with the formate dehydrogenase via the lipid soluble quinol pool. Electron transfer from formate to nitrate is coupled to proton translocation across the cytoplasmic membrane generating proton motive force by a redox loop mechanism. Demethylmenaquinol (DMKH2) has been shown to be a good substrate for NarGHI in nitrate respiration in E. coli.


Pssm-ID: 319879 [Multi-domain]  Cd Length: 363  Bit Score: 71.24  E-value: 1.42e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757782245 118 YTPDTCRQCKDPQCMKVCPIGAITWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLC 186
Cdd:cd10557  174 YLPRICNHCLNPACVAACPSGAIYKREEDGIVLIDQDRCRGWRMCVSACPYKKVYYNWKTGKSEKCIFC 242
EBDH_beta cd10555
beta subunit of ethylbenzene-dehydrogenase (EBDH); This subfamily includes ethylbenzene ...
 118-194 2.95e-14

beta subunit of ethylbenzene-dehydrogenase (EBDH); This subfamily includes ethylbenzene dehydrogenase (EBDH, EC 1.17.99.2), a member of the DMSO reductase family. EBDH oxidizes the hydrocarbon ethylbenzene to (S)-1-phenylethanol. It is a heterotrimer, with the alpha subunit containing the catalytic center with a molybdenum held by two molybdopterin-guanine dinucleotides, the beta subunit containing four iron-sulfur clusters (the electron transfer subunit) and the gamma subunit containing a methionine and a lysine as axial heme ligands. During catalysis, electrons produced by substrate oxidation are transferred to a heme in the gamma subunit and then presumably to a separate cytochrome involved in nitrate respiration.


Pssm-ID: 319877 [Multi-domain]  Cd Length: 316  Bit Score: 70.02  E-value: 2.95e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 118 YTPDTCRQCKDPQCMKVCPIGAITWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLC------GE--- 188
Cdd:cd10555  128 YLPRICNHCTNPACLAACPRKAIYKREEDGIVLVDQDRCRGYRYCVEACPYKKIYFNPVEQKSEKCIFCypriekGVapa 207


                 ....*.
gi 757782245 189 CASACP 194
Cdd:cd10555  208 CARQCV 213
SER_beta cd10556
Beta subunit of selenate reductase; This subfamily includes beta FeS subunit of selenate ...
 118-194 1.10e-13

Beta subunit of selenate reductase; This subfamily includes beta FeS subunit of selenate reductase (SER), a member of the DMSO reductase family. SER catalyzes the reduction of selenate to selenite in bacterial species that can obtain energy by respiring anaerobically with selenate as the terminal electron acceptor. The enzyme comprises three subunits SerABC, forming a heterotrimer, with the catalytic component (alpha-subunit), iron-sulfur protein (beta-subunit) and monomeric b-type heme-containing gamma subunit. Beta subunit contains coordinating one [3Fe-4S] cluster and three [4Fe-4S] clusters and functions as electron carrier.


Pssm-ID: 319878 [Multi-domain]  Cd Length: 287  Bit Score: 67.87  E-value: 1.10e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 118 YTPDTCRQCKDPQCMKVCPIGAITWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLC---------GE 188
Cdd:cd10556  136 YLPRICNHCTYPACLAACPRKAIYKREEDGIVLIDQERCRGYRECVEACPYKKPMYNPTTRVSEKCIGCyprieegdqTQ 215


                 ....*.
gi 757782245 189 CASACP 194
Cdd:cd10556  216 CVSACI 221
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 62-202 1.52e-13

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 64.60  E-value: 1.52e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  62 VTQRARCTGCHRCEISCTNYNDGAVGTFFSRIKIHrhyffgdkgpgsgGGLYGDLNYTPDTCRQCKDPQCMKVCPIGAIT 141
Cdd:cd16370    5 VKDMERCIGCYSCMLACSRRVHKSASLSKSAIRVR-------------TRGGLEGGFTVVVCRACEDPPCAEACPTGALE 71

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757782245 142 wSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLCGECASACPTGALKIIE 202
Cdd:cd16370   72 -PRKGGGVVLDKEKCIGCGNCVKACIVGAIFWDEETNKPIICIHCGYCARYCPHDVLAMEE 131
PRK10882 PRK10882
hydrogenase 2 operon protein HybA;
14-197 1.33e-12

hydrogenase 2 operon protein HybA;


Pssm-ID: 236786 [Multi-domain]  Cd Length: 328  Bit Score: 65.08  E-value: 1.33e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  14 TRLEFLRISGKGLAGLTIAPALLSLFGCKQEDIDsGTVGLI--STpkgvlvtqraRCTGCHRCEISCTNYNDGAV----- 86
Cdd:PRK10882   2 NRRNFLKAASAGALLAGALPSVSHAAAENRPPIP-GALGMLydST----------LCVGCQACVTKCQEINFPERnpqge 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  87 ----------GTFFSRIKIHRhyffgDKGPGSGGGLYGDLNYTPDTCRQCKDPQCMKVCPIGAITWSQEDGCIAVDHRRC 156
Cdd:PRK10882  71 qtwdnpdklsPYTNNIIKVWK-----SGTGVNKDQEENGYAYIKKQCMHCVDPNCVSVCPVSALTKDPKTGIVHYDKDVC 145

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757782245 157 IGCSACTTACP-------WmmatvNTETKKSSKCVLCGE-------------CASACPTGA 197
Cdd:PRK10882 146 TGCRYCMVACPfnvpkydY-----NNPFGAIHKCELCNQkgverldkgglpgCVEVCPTGA 201
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 120-200 3.02e-12

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 61.26  E-value: 3.02e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 120 PDTCRQCKdpQCMKVCPIGAITWSQEDGCIA-------VDHRRCIGCSACTTACPWMMATVNTETKK---SSKCVLCGEC 189
Cdd:cd10549   39 EDKCVFCG--ACVEVCPTGAIELTPEGKEYVpkekeaeIDEEKCIGCGLCVKVCPVDAITLEDELEIvidKEKCIGCGIC 116

                         90
                 ....*....|.
gi 757782245 190 ASACPTGALKI 200
Cdd:cd10549  117 AEVCPVNAIKL 127
PRK10330 PRK10330
electron transport protein HydN;
66-198 4.16e-12

electron transport protein HydN;


Pssm-ID: 182382 [Multi-domain]  Cd Length: 181  Bit Score: 62.21  E-value: 4.16e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  66 ARCTGCHRCEISCT----NYNDGAV---GTFFSRIKIHRHYFFGdkgpgsggglygdlnyTPDTCRQCKDPQCMKVCPIG 138
Cdd:PRK10330  10 SKCIGCRTCEVACVvshqENQDCASltpETFLPRIHVIKGVNVS----------------TATVCRQCEDAPCANVCPNG 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 139 AItwSQEDGCIAVDHRRCIGCSACTTACPW---------------MMATVNTETKKSSKCVLCGE------CASACPTGA 197
Cdd:PRK10330  74 AI--SRDKGFVHVMQERCIGCKTCVVACPYgamevvvrpvirnsgAGLNVRAEKAEANKCDLCNHredgpaCMAACPTHA 151


                 .
gi 757782245 198 L 198
Cdd:PRK10330 152 L 152
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
123-200 1.29e-11

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 62.74  E-value: 1.29e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 123 CRQCKDPQCMKVCPIGAItwSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKK--SSKCVLCGECASACPTGALKI 200
Cdd:COG4624   62 CRCCVAISCIQVRGIIII--DKRGPSIIRDKEKCKNCYPCVRACPVKAIKVDDGKAEidEEKCISCGQCVAVCPFGAITE 139
DMSOR_beta_like cd16368
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 118-207 1.27e-10

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319890 [Multi-domain]  Cd Length: 200  Bit Score: 58.20  E-value: 1.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 118 YTPDTCRQCKDPQCMKVCPIGAITwSQEDGCIAVDHRRCIGCSACTTACPWMM----ATVNTETKKSS---------KCV 184
Cdd:cd16368   86 FIPRRCMHCDNPPCAKLCPFGAAR-KTPEGAVYIDDDLCFGGAKCRDVCPWHIpqrqAGVGIYLHLAPeyagggvmyKCD 164

                         90       100       110
                 ....*....|....*....|....*....|..
gi 757782245 185 LC------GE---CASACPTGALKIIEWKDIT 207
Cdd:cd16368  165 LCkdllaqGKppaCIEACPKGAQYFGPRKEMV 196
NarY COG1140
Nitrate reductase beta subunit [Energy production and conversion, Inorganic ion transport and ...
 118-186 1.30e-10

Nitrate reductase beta subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440755 [Multi-domain]  Cd Length: 485  Bit Score: 59.82  E-value: 1.30e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757782245 118 YTPDTCRQCKDPQCMKVCPIGAITWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETKKSSKCVLC 186
Cdd:COG1140  177 YLPRICEHCLNPACVASCPSGAIYKREEDGIVLVDQDKCRGWRMCVSGCPYKKVYFNWKTGKAEKCIFC 245
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
131-200 6.36e-10

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 56.99  E-value: 6.36e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757782245 131 CMKVCPIGAI--------TWSqedgcIAVDHRRCIGCSACTTACPwMMATVNTETKKSSKCVLCGECASACPTGALKI 200
Cdd:COG0348  184 CRYLCPYGAFqgllsdlsTLR-----VRYDRGDCIDCGLCVKVCP-MGIDIRKGEINQSECINCGRCIDACPKDAIRF 255
W-FDH cd10559
tungsten-containing formate dehydrogenase, small subunit; This subfamily contains beta subunit ...
 66-206 1.31e-09

tungsten-containing formate dehydrogenase, small subunit; This subfamily contains beta subunit of Tungsten-containing formate dehydrogenase (W-FDH), a member of the DMSO reductase family. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319881 [Multi-domain]  Cd Length: 200  Bit Score: 55.52  E-value: 1.31e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  66 ARCTGCHRCEISCTNYND--GAVGTF--------------FSRIKIHRhyffgdkgpGSGGGLYGDLNYTPDTCRQCKDP 129
Cdd:cd10559    7 TRCTACRGCQVACKQWNQlpAEQTKNtgshqnppdlsantYKLVRFNE---------VRNENGKPDWLFFPDQCRHCVTP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 130 QCMKVCPI--GAITWSQEDGCIAVDHRRCIGC-SACTTACPWMMATVNTETKKSSKCVLCGE---------CASACPTGA 197
Cdd:cd10559   78 PCKDAADMvpGAVIQDEATGAVVFTEKTAELDfDDVLSACPYNIPRKNEATGRIVKCDMCIDrvsnglqpaCVKACPTGA 157


                 ....*....
gi 757782245 198 LKIIEWKDI 206
Cdd:cd10559  158 MNFGDRDEM 166
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 155-200 2.48e-09

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 54.27  E-value: 2.48e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 757782245 155 RCIGCSACTTACPWMMATVNTETKKSSK--------CVLCGECASACPTGALKI 200
Cdd:PRK12387  39 QCIGCAACVNACPSNALTVETDLATGELawefnlgrCIFCGRCEEVCPTAAIKL 92
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
151-206 3.76e-08

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 48.57  E-value: 3.76e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757782245 151 VDHRRCIGCSACTTACPW-------MMATVNTEtkkssKCVLCGECASACPTGALKIIEWKDI 206
Cdd:COG2768    8 VDEEKCIGCGACVKVCPVgaisiedGKAVIDPE-----KCIGCGACIEVCPVGAIKIEWEEDE 65
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
120-167 4.76e-08

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 48.57  E-value: 4.76e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 757782245 120 PDTCRQCKdpQCMKVCPIGAItwSQEDGCIAVDHRRCIGCSACTTACP 167
Cdd:COG2768   10 EEKCIGCG--ACVKVCPVGAI--SIEDGKAVIDPEKCIGCGACIEVCP 53
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 120-208 5.22e-08

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 49.70  E-value: 5.22e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 120 PDTCRQCKDpqCMKVCPIGAITWSQEDG---CIAVDHRRCIGCSACTTACPWMMATVNTETKKS-----------SKCVL 185
Cdd:cd10549    5 PEKCIGCGI--CVKACPTDAIELGPNGAiarGPEIDEDKCVFCGACVEVCPTGAIELTPEGKEYvpkekeaeideEKCIG 82

                         90       100
                 ....*....|....*....|...
gi 757782245 186 CGECASACPTGALKIIEWKDITV 208
Cdd:cd10549   83 CGLCVKVCPVDAITLEDELEIVI 105
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
120-167 9.97e-08

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 51.40  E-value: 9.97e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 757782245 120 PDTCRQCKdpQCMKVCPIGAITWsQEDGCIAVDHRRCIGCSACTTACP 167
Cdd:COG1148  495 PEKCTGCG--RCVEVCPYGAISI-DEKGVAEVNPALCKGCGTCAAACP 539
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
151-198 3.86e-07

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 49.47  E-value: 3.86e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 757782245 151 VDHRRCIGCSACTTACPWMMATVNTETK---KSSKCVLCGECASACPTGAL 198
Cdd:COG1148  493 VDPEKCTGCGRCVEVCPYGAISIDEKGVaevNPALCKGCGTCAAACPSGAI 543
PRK08348 PRK08348
NADH-plastoquinone oxidoreductase subunit; Provisional
 147-200 4.17e-07

NADH-plastoquinone oxidoreductase subunit; Provisional


Pssm-ID: 181399 [Multi-domain]  Cd Length: 120  Bit Score: 47.14  E-value: 4.17e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 757782245 147 GCIAVDHRRCIGCSACTTACPWMMATVNTETKK----SSKCVLCGECASACPTGALKI 200
Cdd:PRK08348  35 GKILYDVDKCVGCRMCVTVCPAGVFVYLPEIRKvalwTGRCVFCGQCVDVCPTGALQM 92
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 149-200 5.03e-07

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 45.43  E-value: 5.03e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 757782245 149 IAVDHRRCIGCSACTTACPWMMATVNTETKK--SSKCVLCGECASACPTGALKI 200
Cdd:COG2221   10 PKIDEEKCIGCGLCVAVCPTGAISLDDGKLVidEEKCIGCGACIRVCPTGAIKG 63
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 120-167 5.65e-07

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 45.42  E-value: 5.65e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 757782245 120 PDTCRQCKDpqCMKVCPigAITWSQEDGCIAVDHRRCIGCSACTTACP 167
Cdd:COG4231   21 EDKCTGCGA--CVKVCP--ADAIEEGDGKAVIDPDLCIGCGSCVQVCP 64
sulfite_red_C TIGR02912
sulfite reductase, subunit C; Members of this protein family include the C subunit, one of ...
 135-197 7.35e-07

sulfite reductase, subunit C; Members of this protein family include the C subunit, one of three subunits, of the anaerobic sulfite reductase of Salmonella, and close homologs from various Clostridum species, where the three-gene neighborhood is preserved. Two such gene clusters are found in Clostridium perfringens, but it may be that these sets of genes correspond to the distinct assimilatory and dissimilatory forms as seen in Clostridium pasteurianum. Note that any one of these enzymes may have secondary substates such as NH2OH, SeO3(2-), and SO3(2-). Heterologous expression of the anaerobic sulfite reductase of Salmonella confers on Escherichia coli the ability to produce hydrogen sulfide gas from sulfite. [Central intermediary metabolism, Sulfur metabolism]


Pssm-ID: 131958 [Multi-domain]  Cd Length: 314  Bit Score: 48.32  E-value: 7.35e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757782245  135 CPIGAITWSQED-GCIAV-----DHRRCIGCSACTTACP----WMMATVNTET-KKSSKCVLCGECASACPTGA 197
Cdd:TIGR02912 144 CPNDCAKARMHDfGIIGMtepqyDADRCIGCGACVKVCKkkavGALSFENYKVvRDHSKCIGCGECVLKCPTGA 217
PRK13795 PRK13795
hypothetical protein; Provisional
 131-167 9.64e-07

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 48.45  E-value: 9.64e-07
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 757782245 131 CMKVCPIGAITWSQEDGCIAVDHRRCIGCSACTTACP 167
Cdd:PRK13795 589 CVGACPTGAIRIEEGKRKISVDEEKCIHCGKCTEVCP 625
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 149-202 1.35e-06

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 45.85  E-value: 1.35e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757782245 149 IAVDHRRCIGCSACTTACPWMMATVNTETKKS-------SKCVLCGECASACPTGALKIIE 202
Cdd:cd10549    1 LKYDPEKCIGCGICVKACPTDAIELGPNGAIArgpeideDKCVFCGACVEVCPTGAIELTP 61
NapF COG1145
Ferredoxin [Energy production and conversion];
120-167 2.20e-06

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 47.02  E-value: 2.20e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 757782245 120 PDTCRQCKdpQCMKVCPIGAITWSQEDGCIAVDHRRCIGCSACTTACP 167
Cdd:COG1145  181 AEKCIGCG--LCVKVCPTGAIRLKDGKPQIVVDPDKCIGCGACVKVCP 226
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 149-202 2.44e-06

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 43.54  E-value: 2.44e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 757782245 149 IAVDHRRCIGCSACTTACP-----WMMATVNTETKKSSKCVLCGECASACPTGALKIIE 202
Cdd:COG1146    3 PVIDTDKCIGCGACVEVCPvdvleLDEEGKKALVINPEECIGCGACELVCPVGAITVED 61
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
155-198 4.11e-06

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 45.26  E-value: 4.11e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 757782245 155 RCIGCSACTTACP----WMMATVNTETKKS--------SKCVLCGECASACPTGAL 198
Cdd:PRK05888  59 RCIACKLCAAICPadaiTIEAAEREDGRRRttrydinfGRCIFCGFCEEACPTDAI 114
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 67-168 4.31e-06

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 44.31  E-value: 4.31e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  67 RCTGCHRCEISCTnyndgavgtfFSRIKIHRHYFfgdkgpgSGGGLYGDLNYTPDTCRQCKDpqCMKVCPIGAITwSQED 146
Cdd:cd10549   41 KCVFCGACVEVCP----------TGAIELTPEGK-------EYVPKEKEAEIDEEKCIGCGL--CVKVCPVDAIT-LEDE 100

                         90       100
                 ....*....|....*....|..
gi 757782245 147 GCIAVDHRRCIGCSACTTACPW 168
Cdd:cd10549  101 LEIVIDKEKCIGCGICAEVCPV 122
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 149-204 5.20e-06

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 42.79  E-value: 5.20e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 757782245 149 IAVDHRRCIGCSACTTACPWMMATVNTETKKS---SKCVLCGECASACPTGALKIIEWK 204
Cdd:COG1149    6 PVIDEEKCIGCGLCVEVCPEGAIKLDDGGAPVvdpDLCTGCGACVGVCPTGAITLEERE 64
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 155-199 5.22e-06

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 43.94  E-value: 5.22e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 757782245  155 RCIGCSACTTACPWMMATVNTETKKS------------SKCVLCGECASACPTGALK 199
Cdd:TIGR01971  44 KCIGCTLCAAVCPADAIRVVPAEGEDgkrrlkfyeinfGRCIFCGLCEEACPTDAIV 100
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 120-167 5.40e-06

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 43.12  E-value: 5.40e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 757782245 120 PDTCRQCKdpQCMKVCPIGAITWSqEDGCIAVDHRRCIGCSACTTACP 167
Cdd:COG1144   29 EDKCIGCG--LCWIVCPDGAIRVD-DGKYYGIDYDYCKGCGICAEVCP 73
PRK08222 PRK08222
hydrogenase 4 subunit H; Validated
 152-208 6.35e-06

hydrogenase 4 subunit H; Validated


Pssm-ID: 181301 [Multi-domain]  Cd Length: 181  Bit Score: 44.74  E-value: 6.35e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757782245 152 DHRRCIGCSACTTACPWMMATVNTETKKSS--------KCVLCGECASACPTGALKIIEWKDITV 208
Cdd:PRK08222  36 MPSQCIACGACTCACPANALTIQTDDQQNSrtwqlylgRCIYCGRCEEVCPTRAIQLTNNFELTV 100
NapF COG1145
Ferredoxin [Energy production and conversion];
148-202 6.84e-06

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 45.48  E-value: 6.84e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757782245 148 CIAVDHRRCIGCSACTTACP---------WMMATVNTEtkkssKCVLCGECASACPTGALKIIE 202
Cdd:COG1145  176 KAVIDAEKCIGCGLCVKVCPtgairlkdgKPQIVVDPD-----KCIGCGACVKVCPVGAISLEP 234
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
131-201 7.17e-06

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 45.31  E-value: 7.17e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 131 CMKVCPIGAItwSQEDGCIAVDHRRCIGCSACTTACP------------WMMATVNTETKKSSK------CVLCGECASA 192
Cdd:PRK07118 147 CVAACPFDAI--HIENGLPVVDEDKCTGCGACVKACPrnvielipksarVFVACNSKDKGKAVKkvcevgCIGCGKCVKA 224


                 ....*....
gi 757782245 193 CPTGALKII 201
Cdd:PRK07118 225 CPAGAITME 233
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 120-167 7.65e-06

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 42.43  E-value: 7.65e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 757782245 120 PDTCRQCKdpQCMKVCPIGAITWSQEDG--CIAVDHRRCIGCSACTTACP 167
Cdd:COG1143    1 EDKCIGCG--LCVRVCPVDAITIEDGEPgkVYVIDPDKCIGCGLCVEVCP 48
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 151-202 8.58e-06

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 42.73  E-value: 8.58e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 151 VDHRRCIGCSACTTACP--------WMMATVNTEtkkssKCVLCGECASACPTGALKIIE 202
Cdd:COG1144   27 VDEDKCIGCGLCWIVCPdgairvddGKYYGIDYD-----YCKGCGICAEVCPVKAIEMVP 81
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 149-202 2.52e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 41.18  E-value: 2.52e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 757782245 149 IAVDHRRCIGCSACTTACPwmMATVNTETKK----SSKCVLCGECASACPTGALKIIE 202
Cdd:COG4231   17 YVIDEDKCTGCGACVKVCP--ADAIEEGDGKavidPDLCIGCGSCVQVCPVDAIKLEK 72
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 120-167 2.53e-05

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 40.87  E-value: 2.53e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 757782245 120 PDTCRQCKdpQCMKVCPIGAITWSqEDGCIAVDHRRCIGCSACTTACP 167
Cdd:COG1149   10 EEKCIGCG--LCVEVCPEGAIKLD-DGGAPVVDPDLCTGCGACVGVCP 54
napG PRK09476
quinol dehydrogenase periplasmic component; Provisional
 15-195 3.28e-05

quinol dehydrogenase periplasmic component; Provisional


Pssm-ID: 236534 [Multi-domain]  Cd Length: 254  Bit Score: 43.46  E-value: 3.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  15 RLEFLRISGKGLAGLTIAPALLSLFgCKQedidSGTVGLISTPKGVLVTQR--ARCTGCHRCEISCTnYNDGAVGTFFSR 92
Cdd:PRK09476  11 RRRFLRDVVRTAGGLAAVGVALGLQ-QQQ----ARASGVALRPPGALNENDflSACIRCGLCVQACP-YDTLKLATLASG 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245  93 IKIHRHYFfgdkgpgsggglygdlnyTPDT--CRQCKDPQCMKVCPIGA-------ITWSQEDGCIAVDHRRCIG----- 158
Cdd:PRK09476  85 LSAGTPYF------------------VARDipCEMCEDIPCVKACPSGAldrelvdIDDARMGLAVLVDQENCLNfqglr 146

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 757782245 159 CSACTTACPWMMATVNTETKK---------------SSKCVLCGECASACPT 195
Cdd:PRK09476 147 CDVCYRVCPLIDKAITLELERnertgkhafflptvhSDACTGCGKCEKACVL 198
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 155-200 3.83e-05

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 40.50  E-value: 3.83e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 757782245 155 RCIGCSACTTACP----WMMATVNTETKK--SSKCVLCGECASACPTGALKI 200
Cdd:COG1143    3 KCIGCGLCVRVCPvdaiTIEDGEPGKVYVidPDKCIGCGLCVEVCPTGAISM 54
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 156-201 5.86e-05

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 42.67  E-value: 5.86e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 757782245 156 CIGCSACTTACPW--------MMATVNTEtkkssKCVLCGECASACPTGALKII 201
Cdd:COG2878  139 CIGCGDCIKACPFdaivgaakGMHTVDED-----KCTGCGLCVEACPVDCIEMV 187
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 156-197 8.42e-05

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 39.05  E-value: 8.42e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 757782245  156 CIGCSACTTACP-----WMMATVNTETKK----SSKCVLCGECASACPTGA 197
Cdd:pfam12838   1 CIGCGACVAACPvgaitLDEVGEKKGTKTvvidPERCVGCGACVAVCPTGA 51
PRK14028 PRK14028
pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional
 151-201 9.15e-05

pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional


Pssm-ID: 172522 [Multi-domain]  Cd Length: 312  Bit Score: 42.29  E-value: 9.15e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757782245 151 VDHRRCIGCSACTTACP---WMMATVNTETKKSSK------------CVLCGECASACPTGALKII 201
Cdd:PRK14028 244 IDHSKCIMCRKCWLYCPddaIIEAWREAEGPRGRKfrmkmidfdyqyCKGCGVCAEVCPTGAIQMV 309
PRK08348 PRK08348
NADH-plastoquinone oxidoreductase subunit; Provisional
 116-167 1.22e-04

NADH-plastoquinone oxidoreductase subunit; Provisional


Pssm-ID: 181399 [Multi-domain]  Cd Length: 120  Bit Score: 40.20  E-value: 1.22e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 757782245 116 LNYTPDTCRQCKdpQCMKVCPIGAITWSQEDGCIAVDHRRCIGCSACTTACP 167
Cdd:PRK08348  37 ILYDVDKCVGCR--MCVTVCPAGVFVYLPEIRKVALWTGRCVFCGQCVDVCP 86
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
131-178 1.24e-04

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 39.93  E-value: 1.24e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 757782245 131 CMKVCPIGAItWSQEDGCIAVDHRRCIGCSACTTACPWMMATVNTETK 178
Cdd:PRK09623  59 CWKFCPEPAI-YIKEDGYVAIDYDYCKGCGICANECPTKAITMVKEEK 105
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 123-202 1.45e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 40.70  E-value: 1.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 123 CRQCKDpQCMKVCPIGAI---TWSQED---GCIAVDHRRCI------GCSACTTACPWMMATVNTETKK------SSKCV 184
Cdd:cd16373   55 CDLCCD-ACVEVCPTGALrplDLEEQKvkmGVAVIDKDRCLawqggtDCGVCVEACPTEAIAIVLEDDVlrpvvdEDKCV 133

                         90
                 ....*....|....*...
gi 757782245 185 LCGECASACPTGALKIIE 202
Cdd:cd16373  134 GCGLCEYVCPVEPPKAIV 151
PRK07569 PRK07569
bidirectional hydrogenase complex protein HoxU; Validated
 150-198 1.65e-04

bidirectional hydrogenase complex protein HoxU; Validated


Pssm-ID: 181037 [Multi-domain]  Cd Length: 234  Bit Score: 41.18  E-value: 1.65e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 757782245 150 AVDHRRCIGCSACTTAC-------PWMMATVNTETK----------KSSKCVLCGECASACPTGAL 198
Cdd:PRK07569 142 GIDHNRCVLCTRCVRVCdeiegahTWDVAGRGAKSRvitdlnqpwgTSETCTSCGKCVQACPTGAI 207
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 123-167 2.39e-04

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 41.40  E-value: 2.39e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 757782245 123 CRQCKdpQCMKVCPIGAITWSQEDGCIAVDHRRCIGCSACTTACP 167
Cdd:PRK12771 512 CFECD--NCYGACPQDAIIKLGPGRRYHFDYDKCTGCHICADVCP 554
PRK13795 PRK13795
hypothetical protein; Provisional
 155-194 3.03e-04

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 41.13  E-value: 3.03e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 757782245 155 RCIGCSACTTACPwmmatVNTETKKS---------SKCVLCGECASACP 194
Cdd:PRK13795 582 ECVGCGVCVGACP-----TGAIRIEEgkrkisvdeEKCIHCGKCTEVCP 625
ndhI CHL00014
NADH dehydrogenase subunit I
 155-202 3.48e-04

NADH dehydrogenase subunit I


Pssm-ID: 214334 [Multi-domain]  Cd Length: 167  Bit Score: 39.74  E-value: 3.48e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 757782245 155 RCIGCSACTTACPWMMATVNTETKKSSK-------------CVLCGECASACPTGALKIIE 202
Cdd:CHL00014  60 KCIACEVCVRVCPIDLPVVDWKLETDIRkkrllnysidfgvCIFCGNCVEYCPTNCLSMTE 120
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 116-167 4.34e-04

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 39.15  E-value: 4.34e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 757782245 116 LNYTPDTCRQCKDPqcmkvCPIGAITWSQEDGCIA---VDHRRCIGCSACTTACP 167
Cdd:cd10564   81 LALQGVECRSCQDA-----CPTQAIRFRPRLGGIAlpeLDADACTGCGACVSVCP 130
Fer4_9 pfam13187
4Fe-4S dicluster domain;
155-198 5.52e-04

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 36.76  E-value: 5.52e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 757782245  155 RCIGCSACTTACP---WMM---ATVNTETKKSSKCVLCGECASACPTGAL 198
Cdd:pfam13187   1 KCTGCGACVAACPagaIVPdlvGQTIRGDIAGLACIGCGACVDACPRGAI 50
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
119-202 6.20e-04

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 40.01  E-value: 6.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 119 TPDTCRQCKDPQCMKVCPIGAITWSQEDGCIAVDHRRCIGCSACttacpwmmatvntetkksSKCVLCGECASACPTGAL 198
Cdd:COG4624   47 ACSCCPRCCLCCCCCCRCCVAISCIQVRGIIIIDKRGPSIIRDK------------------EKCKNCYPCVRACPVKAI 108


                 ....
gi 757782245 199 KIIE 202
Cdd:COG4624  109 KVDD 112
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 148-194 7.87e-04

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 36.46  E-value: 7.87e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 757782245  148 CIAVDHRRCIGCSACTTACPWMMATVNTET---------KKSSKCVLCGECASACP 194
Cdd:pfam13237   1 KVVIDPDKCIGCGRCTAACPAGLTRVGAIVerlegeavrIGVWKCIGCGACVEACP 56
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
118-180 8.63e-04

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 39.28  E-value: 8.63e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757782245 118 YTPDTCRQCKDpqCMKVCPIGAITWSQEdgciaVDHRRCIGCSACTTACPWMMATVNTETKKS 180
Cdd:COG0348  207 YDRGDCIDCGL--CVKVCPMGIDIRKGE-----INQSECINCGRCIDACPKDAIRFSSRGEKT 262
QueG COG1600
Epoxyqueuosine reductase QueG (queuosine biosynthesis) [Translation, ribosomal structure and ...
 119-168 1.17e-03

Epoxyqueuosine reductase QueG (queuosine biosynthesis) [Translation, ribosomal structure and biogenesis]; Epoxyqueuosine reductase QueG (queuosine biosynthesis) is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441208 [Multi-domain]  Cd Length: 345  Bit Score: 39.03  E-value: 1.17e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757782245 119 TPDTCRQCKdpQCMKVCPIGAITwsqEDGciAVDHRRCI------------------------GCSACTTACPW 168
Cdd:COG1600  182 VEDHCGSCT--RCLDACPTGAIV---APY--VLDARRCIsyltielkgpipeelrpkmgnriyGCDDCQDVCPW 248
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 123-168 1.38e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 35.58  E-value: 1.38e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 757782245  123 CRQCKDpqCMKVCPIGAITWSQEDGC-----IAVDHRRCIGCSACTTACPW 168
Cdd:pfam12838   1 CIGCGA--CVAACPVGAITLDEVGEKkgtktVVIDPERCVGCGACVAVCPT 49
PRK13984 PRK13984
putative oxidoreductase; Provisional
 182-207 1.64e-03

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 38.59  E-value: 1.64e-03
                         10        20
                 ....*....|....*....|....*.
gi 757782245 182 KCVLCGECASACPTGALKIIEWKDIT 207
Cdd:PRK13984  46 KCIGCGTCSKICPTDAITMVEVPDLP 71
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 149-198 1.76e-03

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 37.62  E-value: 1.76e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 149 IAVDHRRCIGCSACTTAC---------PWMMATVNTETKKSSK---------CVLCGE--CASACPTGAL 198
Cdd:COG0437    8 MVIDLTKCIGCRACVVACkeennlpvgVTWRRVRRYEEGEFPNvewlfvpvlCNHCDDppCVKVCPTGAT 77
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 131-167 1.94e-03

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 38.05  E-value: 1.94e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 757782245 131 CMKVCPIGAITWSqEDGCIAVDHRRCIGCSACTTACP 167
Cdd:COG2878  145 CIKACPFDAIVGA-AKGMHTVDEDKCTGCGLCVEACP 180
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 168-208 2.27e-03

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 35.47  E-value: 2.27e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 757782245 168 WMMATVNTEtkkssKCVLCGECASACPTGALKIIEWKDITV 208
Cdd:COG1149    3 RKIPVIDEE-----KCIGCGLCVEVCPEGAIKLDDGGAPVV 38
PRK08493 PRK08493
NADH-quinone oxidoreductase subunit G;
180-198 2.57e-03

NADH-quinone oxidoreductase subunit G;


Pssm-ID: 236277 [Multi-domain]  Cd Length: 819  Bit Score: 38.15  E-value: 2.57e-03
                         10
                 ....*....|....*....
gi 757782245 180 SSKCVLCGECASACPTGAL 198
Cdd:PRK08493 203 TLDCSFCGECIAVCPVGAL 221
Fer4_9 pfam13187
4Fe-4S dicluster domain;
123-167 2.64e-03

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 34.84  E-value: 2.64e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 757782245  123 CRQCKDpqCMKVCPIGAITWSQEDGCIAVDHR--RCIGCSACTTACP 167
Cdd:pfam13187   2 CTGCGA--CVAACPAGAIVPDLVGQTIRGDIAglACIGCGACVDACP 46
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 120-167 3.03e-03

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 37.84  E-value: 3.03e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 757782245 120 PDTCRQckdpQCMKVCPI-----GAITWSQEDGCIAVDHRRCIGCSACTTACP 167
Cdd:COG1245   14 PKKCNY----ECIKYCPVnrtgkEAIEIDEDDGKPVISEELCIGCGICVKKCP 62
PRK08318 PRK08318
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;
151-195 3.17e-03

NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;


Pssm-ID: 236237 [Multi-domain]  Cd Length: 420  Bit Score: 37.62  E-value: 3.17e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 757782245 151 VDHRRCIGCSACTTAC--------PWMMATVNTETKKSSKCVLCGECASACPT 195
Cdd:PRK08318 339 IDQDKCIGCGRCYIACedtshqaiEWDEDGTRTPEVIEEECVGCNLCAHVCPV 391
PRK13795 PRK13795
hypothetical protein; Provisional
 178-202 3.46e-03

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 37.67  E-value: 3.46e-03
                         10        20
                 ....*....|....*....|....*
gi 757782245 178 KKSSKCVLCGECASACPTGALKIIE 202
Cdd:PRK13795 578 RRAAECVGCGVCVGACPTGAIRIEE 602
PsrB cd10551
polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...
 150-197 3.50e-03

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.


Pssm-ID: 319873 [Multi-domain]  Cd Length: 185  Bit Score: 36.74  E-value: 3.50e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757782245 150 AVDHRRCIGCSACTTAC------PWMMA-----TVNTETKKSSK-------CVLCGE--CASACPTGA 197
Cdd:cd10551    2 VIDLRKCIGCGACVVACkaennvPPGVFrnrvlEYEVGEYPNVKrtflpvlCNHCENppCVKVCPTGA 69
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 155-198 3.79e-03

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 35.69  E-value: 3.79e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 757782245  155 RCIGCSACTTACP--------WMMATVNTetkKSSKCVLCGECASACPTGAL 198
Cdd:TIGR00402  35 VCTRCGECASACEnnilqlgqQGQPTVEF---DNAECDFCGKCAEACPTNAF 83
ACS_1 cd01916
Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and ...
 154-201 3.81e-03

Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and methanogenic organisms and is responsible for the synthesis and breakdown of acetyl-CoA. ACS forms a heterotetramer with carbon monoxide dehydrogenase (CODH) consisting of two ACS and two CODH subunits. CODH reduces carbon dioxide to carbon monoxide and ACS then synthesizes acetyl-CoA from carbon monoxide, CoA, and a methyl group donated by another protein (CoFeSP). ACS has three structural domains, an N-terminal rossman fold domain with a helical region at its N-terminus which interacts with CODH, and two alpha + beta fold domains. A Ni-Fe-S center referred to as the A-cluster is located in the C-terminal domain. A large cavity exists between the three domains which may bind CoA.


Pssm-ID: 238897 [Multi-domain]  Cd Length: 731  Bit Score: 37.77  E-value: 3.81e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 757782245 154 RRCIGCSACTTACP-------WMMATVNTETKKSSK----CVLCGECASACPTGaLKII 201
Cdd:cd01916  365 AKCTDCGWCTRACPnslrikeAMEAAKEGDFSGLADlfdqCVGCGRCEQECPKE-IPII 422
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
120-167 4.06e-03

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 37.48  E-value: 4.06e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 757782245 120 PDTCRQckdpQCMKVCPIG-----AITWSQEDGCIAVDHRRCIGCSACTTACP 167
Cdd:PRK13409  14 PKKCNY----ECIKYCPVVrtgeeTIEIDEDDGKPVISEELCIGCGICVKKCP 62
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 151-202 4.38e-03

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 36.31  E-value: 4.38e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 757782245  151 VDHRRCIGCSACTTACPwMMATVNT----ETKKSSKCVLCGECASACPTGALKIIE 202
Cdd:TIGR01944 110 IDEDNCIGCTKCIQACP-VDAIVGAakamHTVIADECTGCDLCVEPCPTDCIEMIP 164
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 123-202 5.75e-03

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 35.68  E-value: 5.75e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782245 123 CRQCKDpqCMKVCPIGAITWSQE----------DGCIAvdhRRCIGCSACTTACPWMMATVNTETKK-------SSKCVL 185
Cdd:cd10564   47 CTFCGA--CAEACPEGALDPAREapwplraeigDSCLA---LQGVECRSCQDACPTQAIRFRPRLGGialpeldADACTG 121

                         90
                 ....*....|....*..
gi 757782245 186 CGECASACPTGALKIIE 202
Cdd:cd10564  122 CGACVSVCPVGAITLTP 138
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 154-199 6.46e-03

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 35.68  E-value: 6.46e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 757782245 154 RRCIGCSACTTACPWMM--------ATVNTETkksSKCVLCGECASACPTGALK 199
Cdd:cd10564   13 DLCTRCGDCVEACPEGIivrgdggfPELDFSR---GECTFCGACAEACPEGALD 63
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 120-167 6.62e-03

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 33.76  E-value: 6.62e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 757782245  120 PDTCRQCKDpqCMKVCP-----IGAITWSQEDGCIAVDHRRCIGCSACTTACP 167
Cdd:pfam13237   6 PDKCIGCGR--CTAACPagltrVGAIVERLEGEAVRIGVWKCIGCGACVEACP 56
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 182-204 9.26e-03

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 33.87  E-value: 9.26e-03
                         10        20
                 ....*....|....*....|...
gi 757782245 182 KCVLCGECASACPTGALKIIEWK 204
Cdd:COG2221   16 KCIGCGLCVAVCPTGAISLDDGK 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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