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Conserved domains on  [gi|757782262|ref|WP_043000846|]
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MULTISPECIES: Fe-S cluster assembly scaffold SufA [Citrobacter]

Protein Classification

sufA family protein( domain architecture ID 10013260)

sufA family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
sufA PRK09504
iron-sulfur cluster assembly scaffold protein; Provisional
 1-122 1.38e-94

iron-sulfur cluster assembly scaffold protein; Provisional


:

Pssm-ID: 181915  Cd Length: 122  Bit Score: 267.37  E-value: 1.38e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262   1 MELHSGTFNPDDFAWRGLTLTPAAAAHIRELVAKQPGMLGVRLGVKQTGCAGFGYVLDTVSDPEKDDLLFEVEGAKLYVP 80
Cdd:PRK09504   1 MDMHSGTFNPDDFAWQGLTLTPAAAAHIRELMAKQPGMKGVRLGVKQTGCAGFGYVLDSVSEPDKDDLVFEHDGAKLFVP 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 757782262  81 LQAMPFIDGTEVDYVREGLNQLFKFHNPKAQNECGCGESFGV 122
Cdd:PRK09504  81 LQAMPFIDGTEVDYVREGLNQIFKFHNPKAQNECGCGESFGV 122
 
Name Accession Description Interval E-value
sufA PRK09504
iron-sulfur cluster assembly scaffold protein; Provisional
 1-122 1.38e-94

iron-sulfur cluster assembly scaffold protein; Provisional


Pssm-ID: 181915  Cd Length: 122  Bit Score: 267.37  E-value: 1.38e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262   1 MELHSGTFNPDDFAWRGLTLTPAAAAHIRELVAKQPGMLGVRLGVKQTGCAGFGYVLDTVSDPEKDDLLFEVEGAKLYVP 80
Cdd:PRK09504   1 MDMHSGTFNPDDFAWQGLTLTPAAAAHIRELMAKQPGMKGVRLGVKQTGCAGFGYVLDSVSEPDKDDLVFEHDGAKLFVP 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 757782262  81 LQAMPFIDGTEVDYVREGLNQLFKFHNPKAQNECGCGESFGV 122
Cdd:PRK09504  81 LQAMPFIDGTEVDYVREGLNQIFKFHNPKAQNECGCGESFGV 122
sufA_proteo TIGR01997
FeS assembly scaffold SufA; This model represents the SufA protein of the SUF system of ...
 17-122 3.85e-61

FeS assembly scaffold SufA; This model represents the SufA protein of the SUF system of iron-sulfur cluster biosynthesis. This system performs FeS biosynthesis even during oxidative stress and tends to be absent in obligate anaerobic and microaerophilic bacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 131052  Cd Length: 107  Bit Score: 182.34  E-value: 3.85e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262   17 GLTLTPAAAAHIRELVAKQPGMLGVRLGVKQTGCAGFGYVLDTVSDPEKDDLLFEVEGAKLYVPLQAMPFIDGTEVDYVR 96
Cdd:TIGR01997   2 VITLTDAAAIHIRELVAKRPEAVGIRLGVKKTGCAGMEYVLDLVSEPKKDDDLIEHDGAKVFVAPEAVLFILGTQVDFVR 81

                          90       100
                  ....*....|....*....|....*.
gi 757782262   97 EGLNQLFKFHNPKAQNECGCGESFGV 122
Cdd:TIGR01997  82 TTLRQGFKFNNPNATSACGCGESFEL 107
IscA COG0316
Fe-S cluster assembly iron-binding protein IscA [Posttranslational modification, protein ...
 17-122 8.17e-53

Fe-S cluster assembly iron-binding protein IscA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440085 [Multi-domain]  Cd Length: 107  Bit Score: 161.47  E-value: 8.17e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262  17 GLTLTPAAAAHIRELVAKQPG-MLGVRLGVKQTGCAGFGYVLDTVSDPEKDDLLFEVEGAKLYVPLQAMPFIDGTEVDYV 95
Cdd:COG0316    1 PITLTDAAAKRIKRLLAKEGNpGLGLRVGVKGGGCSGFSYGLDFDDEPNEDDLVFEQDGVKVVVDPKSLPYLDGTEIDYV 80

                         90       100
                 ....*....|....*....|....*..
gi 757782262  96 REGLNQLFKFHNPKAQNECGCGESFGV 122
Cdd:COG0316   81 EELLGSGFKFNNPNAKSSCGCGESFSV 107
Fe-S_biosyn pfam01521
Iron-sulphur cluster biosynthesis; This family is involved in iron-sulphur cluster ...
 18-118 3.96e-18

Iron-sulphur cluster biosynthesis; This family is involved in iron-sulphur cluster biosynthesis. Its members include proteins that are involved in nitrogen fixation such as the HesB and HesB-like proteins.


Pssm-ID: 426304  Cd Length: 111  Bit Score: 73.45  E-value: 3.96e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262   18 LTLTPAAAAHIRELVAKQPGMLgvRLGVKQTG-------CA-GFGYVLDTVSDP-EKDDLLFEVEGAKLYVPLQAMPFID 88
Cdd:pfam01521   3 ITITDAAAERLKKLLAGDKKEL--RLDVDDGGgpyskggCSiGGKFSLVLVDEPdPDYDEVIESNGGPIYVDSYSLPFLD 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 757782262   89 -GTEVDYVREGLNQLFKFHNPKAQNECGCGE 118
Cdd:pfam01521  81 eGLTLDFVEDLGTLGLKSDNGNLDGNVGCGD 111
 
Name Accession Description Interval E-value
sufA PRK09504
iron-sulfur cluster assembly scaffold protein; Provisional
 1-122 1.38e-94

iron-sulfur cluster assembly scaffold protein; Provisional


Pssm-ID: 181915  Cd Length: 122  Bit Score: 267.37  E-value: 1.38e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262   1 MELHSGTFNPDDFAWRGLTLTPAAAAHIRELVAKQPGMLGVRLGVKQTGCAGFGYVLDTVSDPEKDDLLFEVEGAKLYVP 80
Cdd:PRK09504   1 MDMHSGTFNPDDFAWQGLTLTPAAAAHIRELMAKQPGMKGVRLGVKQTGCAGFGYVLDSVSEPDKDDLVFEHDGAKLFVP 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 757782262  81 LQAMPFIDGTEVDYVREGLNQLFKFHNPKAQNECGCGESFGV 122
Cdd:PRK09504  81 LQAMPFIDGTEVDYVREGLNQIFKFHNPKAQNECGCGESFGV 122
sufA_proteo TIGR01997
FeS assembly scaffold SufA; This model represents the SufA protein of the SUF system of ...
 17-122 3.85e-61

FeS assembly scaffold SufA; This model represents the SufA protein of the SUF system of iron-sulfur cluster biosynthesis. This system performs FeS biosynthesis even during oxidative stress and tends to be absent in obligate anaerobic and microaerophilic bacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 131052  Cd Length: 107  Bit Score: 182.34  E-value: 3.85e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262   17 GLTLTPAAAAHIRELVAKQPGMLGVRLGVKQTGCAGFGYVLDTVSDPEKDDLLFEVEGAKLYVPLQAMPFIDGTEVDYVR 96
Cdd:TIGR01997   2 VITLTDAAAIHIRELVAKRPEAVGIRLGVKKTGCAGMEYVLDLVSEPKKDDDLIEHDGAKVFVAPEAVLFILGTQVDFVR 81

                          90       100
                  ....*....|....*....|....*.
gi 757782262   97 EGLNQLFKFHNPKAQNECGCGESFGV 122
Cdd:TIGR01997  82 TTLRQGFKFNNPNATSACGCGESFEL 107
IscA COG0316
Fe-S cluster assembly iron-binding protein IscA [Posttranslational modification, protein ...
 17-122 8.17e-53

Fe-S cluster assembly iron-binding protein IscA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440085 [Multi-domain]  Cd Length: 107  Bit Score: 161.47  E-value: 8.17e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262  17 GLTLTPAAAAHIRELVAKQPG-MLGVRLGVKQTGCAGFGYVLDTVSDPEKDDLLFEVEGAKLYVPLQAMPFIDGTEVDYV 95
Cdd:COG0316    1 PITLTDAAAKRIKRLLAKEGNpGLGLRVGVKGGGCSGFSYGLDFDDEPNEDDLVFEQDGVKVVVDPKSLPYLDGTEIDYV 80

                         90       100
                 ....*....|....*....|....*..
gi 757782262  96 REGLNQLFKFHNPKAQNECGCGESFGV 122
Cdd:COG0316   81 EELLGSGFKFNNPNAKSSCGCGESFSV 107
TIGR00049 TIGR00049
Iron-sulfur cluster assembly accessory protein; Proteins in this subfamily appear to be ...
 19-122 1.19e-45

Iron-sulfur cluster assembly accessory protein; Proteins in this subfamily appear to be associated with the process of FeS-cluster assembly. The HesB proteins are associated with the nif gene cluster and the Rhizobium gene IscN has been shown to be required for nitrogen fixation. Nitrogenase includes multiple FeS clusters and many genes for their assembly. The E. coli SufA protein is associated with SufS, a NifS homolog and SufD which are involved in the FeS cluster assembly of the FhnF protein. The Azotobacter protein IscA (homologs of which are also found in E.coli) is associated which IscS, another NifS homolog and IscU, a nifU homolog as well as other factors consistent with a role in FeS cluster chemistry. A homolog from Geobacter contains a selenocysteine in place of an otherwise invariant cysteine, further suggesting a role in redox chemistry. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 272875 [Multi-domain]  Cd Length: 105  Bit Score: 143.10  E-value: 1.19e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262   19 TLTPAAAAHIRELVAKQPGM-LGVRLGVKQTGCAGFGYVLDTVSDPEKDDLLFEVEGAKLYVPLQAMPFIDGTEVDYVRE 97
Cdd:TIGR00049   1 TLTDSAAKRIKALLAGEGEPnLGLRVGVKGGGCSGLQYGLEFDDEPNEDDEVFEQDGVKVVVDPKSLPYLDGSEIDYVEE 80

                          90       100
                  ....*....|....*....|....*
gi 757782262   98 GLNQLFKFHNPKAQNECGCGESFGV 122
Cdd:TIGR00049  81 LLGSGFTFTNPNAKGTCGCGKSFSV 105
IscA TIGR02011
iron-sulfur cluster assembly protein IscA; This model represents the IscA component of the ISC ...
 18-122 3.38e-40

iron-sulfur cluster assembly protein IscA; This model represents the IscA component of the ISC system for iron-sulfur cluster assembly. The ISC system consists of IscRASU, HscAB and an Isc-specific ferredoxin. IscA previously was believed to act as a scaffold and now is seen as an iron donor protein. This clade is limited to the proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 213674  Cd Length: 105  Bit Score: 129.56  E-value: 3.38e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262   18 LTLTPAAAAHIRELVAKQPGMLGVRLGVKQTGCAGFGYVLDTVSDPEKDDLLFEVEGAKLYVPLQAMPFIDGTEVDYVRE 97
Cdd:TIGR02011   1 ITLTDSAAARVNTFLANRGKGFGLRLGVKTSGCSGMAYVLEFVDEPTPDDIVFEDKGVKIVIDGKSLQYLDGTQLDFVKE 80

                          90       100
                  ....*....|....*....|....*
gi 757782262   98 GLNQLFKFHNPKAQNECGCGESFGV 122
Cdd:TIGR02011  81 GLNEGFKFTNPNVKDECGCGESFHV 105
iscA PRK09502
iron-sulfur cluster assembly protein IscA;
18-122 5.60e-35

iron-sulfur cluster assembly protein IscA;


Pssm-ID: 181914 [Multi-domain]  Cd Length: 107  Bit Score: 116.51  E-value: 5.60e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262  18 LTLTPAAAAHIRELVAKQPGMLGVRLGVKQTGCAGFGYVLDTVSDPEKDDLLFEVEGAKLYVPLQAMPFIDGTEVDYVRE 97
Cdd:PRK09502   3 ITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKE 82

                         90       100
                 ....*....|....*....|....*
gi 757782262  98 GLNQLFKFHNPKAQNECGCGESFGV 122
Cdd:PRK09502  83 GLNEGFKFTNPNVKDECGCGESFHV 107
Fe-S_biosyn pfam01521
Iron-sulphur cluster biosynthesis; This family is involved in iron-sulphur cluster ...
 18-118 3.96e-18

Iron-sulphur cluster biosynthesis; This family is involved in iron-sulphur cluster biosynthesis. Its members include proteins that are involved in nitrogen fixation such as the HesB and HesB-like proteins.


Pssm-ID: 426304  Cd Length: 111  Bit Score: 73.45  E-value: 3.96e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262   18 LTLTPAAAAHIRELVAKQPGMLgvRLGVKQTG-------CA-GFGYVLDTVSDP-EKDDLLFEVEGAKLYVPLQAMPFID 88
Cdd:pfam01521   3 ITITDAAAERLKKLLAGDKKEL--RLDVDDGGgpyskggCSiGGKFSLVLVDEPdPDYDEVIESNGGPIYVDSYSLPFLD 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 757782262   89 -GTEVDYVREGLNQLFKFHNPKAQNECGCGE 118
Cdd:pfam01521  81 eGLTLDFVEDLGTLGLKSDNGNLDGNVGCGD 111
PLN03082 PLN03082
Iron-sulfur cluster assembly; Provisional
 20-122 1.45e-16

Iron-sulfur cluster assembly; Provisional


Pssm-ID: 215564  Cd Length: 163  Bit Score: 71.11  E-value: 1.45e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262  20 LTPAAAAHIRELVAKQPGMLG--VRLGVKQTGCAGFGYVLDTVSDPEKDDLLFEVEGAKLYVPLQAMPFIDGTEVDYVRE 97
Cdd:PLN03082  57 MTDNCIRRLKELQTSEPSAEDkmLRLSVETGGCSGFQYVFELDDKTNSDDRVFEKDGVKLVVDNISYDFVKGATVDYVEE 136

                         90       100
                 ....*....|....*....|....*.
gi 757782262  98 GLNQLFKFH-NPKAQNECGCGESFGV 122
Cdd:PLN03082 137 LIRSAFVVStNPSAVGGCSCKSSFMV 162
PRK13623 PRK13623
iron-sulfur cluster insertion protein ErpA; Provisional
 18-122 7.40e-15

iron-sulfur cluster insertion protein ErpA; Provisional


Pssm-ID: 184186  Cd Length: 115  Bit Score: 65.33  E-value: 7.40e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262  18 LTLTPAAAAHIRELVAKQPGM-LGVRLGVKQTGCAGF--GYVLD-TVSDpekDDLLFEVEGAKLYVPLQAMPFIDGTEVD 93
Cdd:PRK13623  10 LVFTDAAAAKVKELIEEEGNPdLKLRVYITGGGCSGFqyGFTFDeQVNE---DDTTIEKQGVTLVVDPMSLQYLVGAEVD 86

                         90       100       110
                 ....*....|....*....|....*....|
gi 757782262  94 YvREGLN-QLFKFHNPKAQNECGCGESFGV 122
Cdd:PRK13623  87 Y-TEGLEgSRFVIKNPNAKTTCGCGSSFSI 115
PRK11190 PRK11190
iron-sulfur cluster biogenesis protein NfuA;
18-110 5.94e-05

iron-sulfur cluster biogenesis protein NfuA;


Pssm-ID: 183027 [Multi-domain]  Cd Length: 192  Bit Score: 40.38  E-value: 5.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782262  18 LTLTPAAAAHIRELVAKQPGMLGVRLGVKQTGCA----GFGYV-LDTVsdpEKDDLLFEVEGAKLYVPLQAMPFIDGTEV 92
Cdd:PRK11190   2 ITISDAAQAHFAKLLANQEEGTQIRVFVINPGTPnaecGVSYCpPDAV---EATDTELKFDGFSAYVDELSAPFLEDAEI 78

                         90       100
                 ....*....|....*....|
gi 757782262  93 DYVREGL-NQL-FKFHNPKA 110
Cdd:PRK11190  79 DFVTDQLgSQLtLKAPNAKM 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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